#NHS Blood and Transplant

[insidecroydon]

Millwall and the Co-op Bank back Donate Breaks blood scheme

Supplies of blood for life-saving transfusions in NHS trauma centres across England remain under Amber alert, with more O-negative and black-heritage donors urgently needed. Amber alert: stocks of donated blood in key groups have not recovered since the summer cyber attack This has prompted the NHS to start a campaign, partnering leading commercial organisations, ranging from the Co-operative…

[cilginfizikcilervbi]

İnsanlara İlk Kez Yapay Kan Aktarıldı

İnsanlara İlk Kez Yapay Kan Aktarıldı Nadir hastalıklarla mücadele etmeyi amaçlayan dünyanın ilk denemesinde laboratuvarda üretilen kan insanlara aktarıldı. İngiltere’deki araştırmacıların kan bozuklukları ve nadir kan türleri olan insanlar için tedaviyi önemli ölçüde iyileştirebileceğini söylediği dönüm noktası niteliğindeki bir klinik çalışmada, bir laboratuvarda üretilen kan ilk kez…

[louisferrignojr]

there's just so much here and i can't find the original post and anyway i don't want to go off at OP so i'm making my own post:

FIRST THINGS FIRST, doctors and medical professional are sworn in by The Hippocratic Oath - this is from an article dated in 2001, and under normal circumstances I'd look for something more recent but for the sake of this post, since Evan Buckley was born in 1992, it'll suffice. (and i'm not going to sit here and examine the limitations and criticisms okay. you can read the article if you're interested.)

the point is no medical professional would approve of a procedure that puts an infant child through immense pain in order to harvest bone marrow and treat another child, no matter how sick that older child would be. i'm not sure why I even need to back up my claims for this because it's just a logical fact that no doctor would inflict pain of that level, even if the parents of said infant brought him to the doctor and said they want to put their child through this procedure. quite frankly, they'd have social services called because doctors are mandatory reporters.

which brings me to the second point: to think that the buckley parents would inflict pain of that level on their infant child is fucking bizarre, or that they would not tend to their fussy baby. there's literally nothing in canon to suggest that buck wasn't taken care of as a baby. even if his parents were emotionally absent and neglectful and let maddie step up to provide the comfort a child needs. i mean. it's a fucking reach.

so how is the procedure done? -> link from the NHS website which very plainly explains stem cells are harvested from the placenta and umbilical cord to treat cancers, immune deficiencies, and genetic disorders.

Baby bred to provide stem cells for sister (2000)

Placental blood as a source of hematopoietic stem cells for transplantation into unrelated recipients (1996)

i can't find anything earlier than 1996 but quite frankly i don't think i have to. that's only 4 years before buck was born. i think it'll suffice.

tl;dr this is the dumbest take i have seen and i think a very quick 5-minute google search disproves OP's "headcanon" so i'm gonna go ahead and take that bet for 0 dollars. there's 0 % chance that happened.

y'all gotta stop coming up with scenarios that put buck through worse things that canon already has because it's giving woobification. because it's not bad enough that his first experience that pain = love was at 5 years old which is very transparently depicted in canon. what the fuck is wrong with y'all.

and i'm not even gonna touch upon the reblogger's tags about how buck is "predisposed" to "subbing" for.. this.. reason.. of all things... because i see bad BDSM takes every day on this godforsaken website anyway.

[the-magnusinstitute]

All staff and visitors,

To show support for the NHS, we are running a blood donation event at 12:00 today in the library. Please sign up on our website at least three hours beforehand so we know how many people to expect, and consider donating to the NHS Blood and Transplant Charity Fund.

All blood must be sourced directly from your body! Our police liaison Tim will be on duty for the entire four hour event and you will be prosecuted!

[if-you-got-a-heart-at-all]

nhs blood and transplant have sent me a google maps link to where my donated blood is now.. in case i want to visit i guess???

[head-post]

Hackers publish NHS patients’ data after “demanding ransom”

The data from the ransomware virus attack allegedly hit the web weeks after a cyberattack halted operations and tests at major London hospitals, The Guardian reported.

The cyberattack targeted Synnovis, a private pathology firm that analyses blood tests for Guy’s and St Thomas’ NHS Foundation Trust (GSTT) and King’s College Trust, on June 3, forcing the capital’s hospitals to cancel nearly 1,600 operations and outpatient appointments.

On Friday, NHS England said that “it has learnt that last night a group of cyber criminals published data they claim belongs to Synnovis and was stolen in this attack. We realise how distressing this event can be for many people. We are taking it very seriously.”

In the attack, hackers from the criminal group Qilin infiltrated Synnovis’ IT system and locked the computer system, encrypting its files to extort fees to regain access. The trusts had contracts totalling just under £1.1bn with Synnovis to provide services vital to the smooth running of the NHS.

Qilin published 104 files, each containing 3.7GB of data, on the messaging platform. The message ended with an image of the Synnovis logo, a description of the company and a link to its website. The Guardian was unable to confirm the contents of the message, but the BBC reported on Friday that the data included patient names, dates of birth, NHS numbers and descriptions of blood tests, although it is not known whether test results were also leaked.

Vulnerability of the UK healthcare sector

NHS England said it is currently analysing the data with the National Cyber Security Centre and other partners to confirm whether the data was taken from Synnovis systems and what information it contained.

Typically, the release of stolen data by ransomware gangs indicates that Synnovis has not made payment – usually demanded in the cryptocurrency bitcoin – for decrypting its systems or deleting stolen files.

Don Smith, vice president of threat research at Secureworks, a cybersecurity firm, said the attack highlighted the vulnerability of the healthcare sector, as huge data sets make it a prime target. The Qilin attack follows the hacking of NHS Dumfries and Galloway health board, which resulted in the theft of patient data. He also added:

“It follows closely in the wake of attacks on the NHS in Dumfries and Galloway and underlines that this sector, which is incredibly rich in data, must be protected.”

Since the hack began, seven hospitals run by two NHS trusts have experienced major disruption, including the cancellation or postponement of planned operations. Between June 3 and 9, two major London trusts postponed 832 surgical procedures, including cancer and organ transplants.

The disruptions affected Guy’s, St Thomas’ and King’s College, as well as the Evelina children’s hospital, Royal Brompton, the Harefield specialist heart and lung hospitals and the Princess Royal hospital in Orpington.

Read more HERE

[alwaysahiccupandastrid]

Rowling didn't say anything wrong though. There are various medical concerns that take place when a transitioned person donates blood. Stop making everything a fucking issue about everything and misinterpreting people. You so called woke left minded thick headed liberals are so far off in the head, not even a slap could bring you back from whatever deluded fantasy you're living in

Hey friend! Thanks for your polite and dignified reply - you’re truly showing me that the far right aren’t rude, unkind or anything negative right now. You’ve definitely convinced me with your kind words.

Seriously though… it’s bold of you to assume that donated blood isn’t thoroughly checked for ANY illnesses, diseases etc. before it’s given to a patient. They literally test EVERY bag of blood to be safe. So these so called “medical concerns” you have regarding trans people donating is unfounded.

From the NHS blood and transplant website:

Have a nice day, and remember:

[worldofmedicine]

Blood Supply Disruption in England After Cyber Attack

Blood supplies in England continue to be impacted by a June ransomware attack on Synnovis, an NHS pathology services provider. The attack disrupted IT systems, affecting hospitals’ ability to conduct blood tests, leading to a shortage of O-type blood. In response, NHS Blood and Transplant (NHSBT) issued an “amber alert” in July, urging hospitals to limit O-type blood usage to essential…

[drgauravkharya]

Dr. Gaurav Kharya: Leading Pediatric Oncologist and Bone Marrow Transplant Specialist in Delhi

Dr. Gaurav Kharya, is an internationally renowned Pediatric Hematologist and Oncologist, known for his expertise in bone marrow transplantation (BMT) and cell and gene therapy. With over 20 years of experience, Dr. Kharya has revolutionized the treatment of pediatric cancer and blood disorders in India, offering hope to patients with complex conditions such as leukemia, sickle cell anemia, thalassemia, and aplastic anemia.

Dr. Gaurav Kharya's Medical Expertise

Dr. Kharya specializes in haploidentical bone marrow transplants,

a procedure used when a 100% HLA match is not available, making it accessible to a wide range of patients. His pioneering work in this area has made him a sought-after expert, particularly for children with blood disorders who lack fully matched donors. He has successfully performed more than 1,000 bone marrow transplants, including over 100 for patients with sickle cell disease (SCD)—the highest by any doctor in India.

Advanced pediatric cancer treatment

As the Clinical Lead at the Center for Bone Marrow Transplant and Cellular Therapy at Apollo Hospitals in New Delhi, Dr. Kharya offers advanced treatment options for pediatric patients. His approach includes cutting-edge therapies like CAR T-cell therapy and gene manipulation, giving children with aggressive cancers and hemoglobinopathies a chance of long-term remission.

Dr. Kharya's international training at prestigious institutions,

including The Great North Children's Hospital in the UK and Imperial College Healthcare NHS Trust in London, has shaped his world-class expertise. He continually brings the latest advancements in pediatric oncology and bone marrow transplantation to his practice in India.

Specialization in Haploidentical Transplants

Dr. Gaurav Kharya is a leading advocate for haploidentical transplants, where the donor is a half-match, usually a family member. Thanks to technological advances, this form of transplant has become increasingly successful, especially for children with diseases like Thalassemia and sickle cell anemia. Dr. Kharya’s work in this field has brought hope to families who previously faced limited treatment options.

Conditions Treated by Dr. Gaurav Kharya

Dr. Kharya treats a wide range of pediatric cancers and hematological conditions, including:

Acute lymphoblastic leukemia (ALL).

Acute Myeloid Leukemia (AML)

Non-Hodgkin's lymphoma

Sickle cell anemia

Thalassemia

Aplastic anemia

Primary Immunodeficiency Disorders

His holistic approach ensures that each child receives personalized care, from diagnosis to treatment and post-transplant recovery.

Achievements and contributions to medical research

Dr. Kharya is not only a skilled clinician but also an active contributor to medical research. He has published extensively on bone marrow transplantation and cell therapy, particularly in the development of new treatment protocols for pediatric cancer and blood disorders. His work in gene therapy and immunotherapy is paving the way for groundbreaking treatments that are set to transform the future of cancer care in India.

Personalized care and patient support

Dr. Kharya emphasizes compassionate care, guiding families through the often-complex process of bone marrow transplantation. He works closely with his team of specialists to ensure that every patient receives the highest level of care, from pre-transplant conditioning to post-transplant recovery.

Families under his care benefit from his dedication to patient education and support. Dr. Kharya ensures that parents understand the intricacies of their child’s treatment plan, including the risks, benefits, and necessary precautions post-transplant.

A Visionary Leader in Pediatric Oncology

Dr. Gaurav Kharya’s vision is to make advanced treatment options like bone marrow transplantation and CAR T-cell therapy accessible to all children in need. Through his work at Apollo Hospitals and Cellogen Therapeutics, he continues to push the boundaries of pediatric cancer care, giving hope to countless families.

[myserendipities]

"The discovery of a new blood group, MAL, has solved a 50-year-old mystery. Researchers from NHS Blood and Transplant (Bristol), NHSBT's International Blood Group Reference Laboratory (IBGRL) and the University of Bristol identified the genetic background of the previously known but mysterious AnWj blood group antigen. The findings allow identification and treatment of rare patients lacking this blood group. Some people can lack this blood group due to the effect of illness, but the rare inherited form of the AnWj-negative phenotype has only been found in a handful of individuals—though due to this discovery it will now be easier to find others in the future. If people who are AnWj-negative receive AnWj-positive blood they could have a transfusion reaction, and this research allows development of new genotyping tests for detecting such rare individuals and reducing the risk of transfusion-associated complications. The AnWj antigen—an antigen is a surface marker—was discovered in 1972 but its genetic background was unknown until now. The new research, published in Blood, establishes a new blood group system (MAL), the 47th ever to be discovered, as home to the AnWj antigen. The research team established that AnWj is carried on the Mal protein. More than 99.9% of people are AnWj-positive, and such individuals were shown to express full-length Mal protein on their red cells, which was not present on the cells of AnWj-negative individuals. The team identified homozygous deletions in the MAL gene associated with the inherited AnWj-negative phenotype. The most common reason for being AnWj-negative is due to suffering from a hematological disorder or some types of cancer which suppress antigen expression. Only a very small number of people are AnWj-negative due to a genetic cause. There were five genetically AnWj negative individuals in the study including a family of Arab-Israelis. The blood tested included a sample given by a lady in 2015 who was the first AnWj negative person to be discovered in the 1970s. "There is so much work that goes into proving that a gene does actually encode a blood group antigen, but it is what we are passionate about, making these discoveries for the benefit of rare patients around the world. "Now genotyping tests can be designed to identify genetically AnWj-negative patients and donors. Such tests can be added to the existing genotyping platforms." source: https://medicalxpress.com/news/2024-09-blood-group.html

[insidecroydon]

'Perfect storm' forces NHS to repeat appeal for blood donors

The NHS has repeated its emergency appeal for blood donors to come forward, especially across London, as stocks of blood have fallen to unprecedentedly low levels. Book now: the NHS needs blood donors to come forward urgently The fall in stocks is due to what the NHS describes as “a perfect storm” of increased demand of O-type blood from hospitals following the recent cyber attack which has…

[puravibenamastes-blog]

Cientistas descobrem novo sistema de grupo sanguíneo

Uma equipe de cientistas britânicos descobriu um novo sistema de grupo sanguíneo raro: o MAL (que vem da proteína de mielina e linfócitos). A descoberta, liderada por pesquisadores da autoridade de saúde do Reino Unido NHS Blood and Transplant com auxílio da Universidade de Bristol, resolveu um mistério de 52 anos em torno da origem genética do antígeno AnWj. Leia mais (09/25/2024 – 07h00) Artigo…

[news4trafford]

Organ Donation Week - almost 11k lives in saved through organ donation

This Organ Donation Week (23– 29 September) NHS Blood and Transplant is celebrating the fact that the NHS Organ Donor Register has been helping to save lives for 30 years through the gift of organ donation – with more than 2.6 million people in the North West declaring their willingness to donate their organs after death. Since the creation of the NHS Organ Donor Register in 1994, more than…

[notiziariofinanziario]

Identificato un nuovo gruppo sanguigno

I ricercatori erano sulle tracce del nuovo gruppo sanguigno da oltre mezzo secolo, da quando fu trovata una donna misteriosamente priva della molecola che è presente sulla superficie dei globuli rossi della quasi totalità delle persone. La scoperta dell'origine genetica di questa condizione, porta a 47 il numero dei sistemi di gruppi sanguigni noti finora (tra cui i celebri sistemi ABO e Rh) e apre la strada a trasfusioni di sangue più sicure. Le possibili conseguenze future I risultati di questa ricerca permetteranno infatti di sviluppare nuovi test genetici per rilevare quei rari pazienti che sono AnWj-negativi, riducendo così il rischio di complicazioni associate alla trasfusione. La maggior parte delle persone AnWj-negative deve la loro condizione a malattie ematologiche o a particolari forme di tumore che sopprimono l'espressione dell'antigene normalmente presente sulla proteina Mal. Solo un numero molto esiguo di persone è AnWj-negativo per una causa genetica. I ricercatori l'hanno scoperta esaminando non solo il sangue della paziente identificata nel 1972, ma anche quello dei membri di una famiglia arabo-israeliana con cinque individui AnWj-negativi. Per ciascuna persona è stato sequenziato l'intero esoma, ovvero il Dna che codifica proteine. Dai risultati è emerso che i rari casi genetici di negatività all'antigene AnWj sono dovuti a delezioni di sequenze di Dna in entrambe le copie del gene Mal.Lo studio "rappresenta un enorme risultato e il culmine di un lungo lavoro di squadra, per stabilire finalmente questo nuovo sistema di gruppi sanguigni ed essere in grado di offrire la migliore assistenza a pazienti rari ma importanti - commenta la prima autrice dello studio, Louise Tilley del Nhs Blood and Transplant di Bristol -. Il lavoro è stato difficile perché i casi genetici sono molto rari. Non avremmo raggiunto questo obiettivo senza il sequenziamento dell'esoma, perché il gene che abbiamo identificato non era un candidato ovvio e si sa poco della proteina Mal nei globuli rossi". Read the full article

[tradmais]

Dispositivo vestível de imagem cerebral mede atividade no cérebro de bebêsDestacando como os bebês respondem em situações do mundo real. Uma nova tecnologia que usa ondas de luz para medir a atividade no cérebro de bebês forneceu o quadro mais completo até o momento de funções como audição, visão e processamento cognitivo fora de um scanner cerebral convencional, em um novo estudo liderado por pesquisadores da UCL e Birkbeck. O capacete de imagem cerebral vestível encontrou atividade inesperada no córtex pré-frontal, uma área do cérebro que processa emoções em resposta a estímulos sociais, parecendo confirmar que os bebês começam a processar o que está acontecendo com eles em situações sociais já aos cinco meses de idade. 31 minutos atrás Nova abordagem do modelo de difusão resolve o problema da proporção de aspectoImagens estranhas de IA logo se tornarão coisa do passado. O novo método dos cientistas da computação da Rice University para gerar imagens com modelos de difusão pré-treinados, uma classe de modelos de IA generativos que "aprendem" adicionando camada após camada de ruído aleatório às imagens em que são treinados e, então, geram novas imagens removendo o ruído adicionado, pode ajudar a resolver o problema da proporção de aspecto. 31 minutos atrás Novo sistema de grupo sanguíneo descobertoEla resolve um mistério de 50 anos. Pesquisadores do NHS Blood and Transplant (Bristol), do International Blood Group Reference Laboratory (IBGRL) do NHSBT e da University of Bristol descobriram um novo sistema de grupo sanguíneo - MAL. O fenótipo herdado do grupo sanguíneo AnWj-negativo é causado pela homozigose para deleção no MAL, codificando a proteína mielina e linfócito. 31 minutos atrás Pequeno buraco negro oculto é encontrado em sistema binário incomumNo sistema binário G3425. Recentemente, cientistas chineses usaram métodos de velocidade radial e astrometria para descobrir um promissor buraco negro de lacuna de massa no sistema binário G3425. Ele tem uma massa de cerca de 3,6 vezes a do Sol, que pode variar de 3,1 a 4,4 vezes a do Sol. Como nenhuma luz vem de mais nada no sistema, esse companheiro escuro deve ser um buraco negro, com sua massa na faixa de "lacuna de massa". 31 minutos atrás Buracos negros supermassivos podem matar de fome suas galáxias hospedeirasEsta galáxia está essencialmente "morta". Usando o Telescópio Espacial James Webb da NASA/ESA, astrônomos confirmaram que buracos negros supermassivos podem matar de fome suas galáxias hospedeiras quando ficam sem combustível para formar novas estrelas. Uma equipe internacional, incluindo a Universidade de Cambridge, observou uma galáxia similar em tamanho à Via Láctea de cerca de dois bilhões de anos após o Big Bang. Esta galáxia tem um buraco negro supermassivo em seu centro, mas está "morta" porque parou de fazer novas estrelas. 31 minutos atrás O mecanismo por trás da organização espacial do DNA Em mamíferos, os embriões iniciais têm uma maneira única de organizar seus genes perto da lâmina nuclear, mas o processo ainda precisa ser totalmente compreendido. Cientistas do Kind Group descobriram novos detalhes sobre a organização do DNA em células embrionárias iniciais. Logo após a fertilização, cada célula pode se transformar em qualquer tipo de célula. Os pesquisadores estudaram como o DNA é organizado explicitamente durante esses estágios iniciais críticos do desenvolvimento. 31 minutos atrás Novas proteínas regulam membranas celularesO complexo do canal iônico desencadeia a mistura de lipídios. Cientistas do Instituto de Ciências Integradas de Células e Materiais da Universidade de Kyoto descobriram como as células controlam a distribuição de fosfolipídios em suas membranas. Esses lipídios, essenciais para a estabilidade celular, geralmente são espalhados de forma desigual e podem mudar rapidamente em resposta a sinais, um processo conhecido como embaralhamento de fosfolipídios.

Esse processo é crucial para funções como coagulação sanguínea e remoção de resíduos. 3 horas atrás Estudo revela fatos sobre a puberdade adolescente na era do geloAvaliação da puberdade em jovens europeus do Paleolítico Superior. Novas pesquisas mostram que os adolescentes da Era Glacial de 25.000 anos atrás passaram pela puberdade de forma muito parecida com os adolescentes de hoje. Um estudo de 13 humanos antigos com idades entre 10 e 20 anos, publicado no Journal of Human Evolution, encontrou marcadores ósseos que revelaram estágios da puberdade. Liderados por April Nowell da UVic, os pesquisadores usaram técnicas desenvolvidas por Mary Lewis para examinar o crescimento dos dentes e dos ossos. 3 horas atrás Dietas ricas em gordura e açúcar durante a gravidez aumentam os riscos futuros para a saúde dos bebêsDieta materna rica em gordura afeta o coração fetal em estudo com primatas. Bebês nascidos de mães obesas têm mais probabilidade de desenvolver problemas cardíacos e diabetes quando adultos. Pesquisas no Journal of Physiology mostram que uma dieta rica em gordura e açúcar durante a gravidez interrompe um hormônio tireoidiano essencial no coração fetal, impactando seu desenvolvimento. Mesmo com pesos médios ao nascer, esses bebês podem se tornar resistentes à insulina mais tarde, aumentando o risco de doenças cardíacas e diabetes. 3 horas atrás Nova técnica torna satélite de órbita baixa mais barato e simples de projetarUma simples mudança pode tornar os satélites em órbita baixa da Terra de alta capacidade Pesquisadores da Princeton Engineering e da Yang Ming Chiao Tung University em Taiwan inventaram uma técnica que permite que antenas de satélite de órbita baixa gerenciem sinais para vários usuários ao mesmo tempo, reduzindo drasticamente o hardware necessário. A estratégia se baseia em uma técnica comum para fortalecer as comunicações posicionando conjuntos de antenas para direcionar um feixe de ondas de rádio precisamente onde ele é necessário. 2 dias atrás Um deslizamento de terra causou um mega-tsunami na GroenlândiaIsso fez a Terra vibrar por nove dias Um deslizamento de terra em uma parte remota da Groenlândia causou um mega-tsunami que se deslocou para frente e para trás através de um fiorde por nove dias, gerando vibrações por toda a Terra, de acordo com um novo estudo envolvendo pesquisadores da UCL. O estudo concluiu que esse movimento de água foi a causa de um misterioso sinal sísmico global que durou nove dias e intrigou os sismólogos em setembro de 2023. 2 dias atrás Transformando simulação de ondas com o software TMATSOLVER Um novo pacote de software desenvolvido por pesquisadores da Macquarie University pode modelar com precisão a maneira como as ondas - som, água ou luz - são espalhadas quando encontram configurações complexas de partículas. Isso melhorará muito a capacidade de projetar rapidamente metamateriais - materiais artificiais interessantes usados ​​para amplificar, bloquear ou desviar ondas. 2 dias atrás

[medisaglik]

Yeni Kan Grubu MAL: Nadir Hastalara Umut Olacak Keşif!

Yeni Bir Çığır: MAL Kan Grubu Keşfi 50 Yıllık Araştırmanın Kazanımı İngiltere’deki kan grubu araştırmalarında çarpıcı bir gelişme yaşandı. Araştırmacılar, 50 yıllık yoğun çalışmalar sonucunda yeni bir kan grubu olan MAL kan grubunu keşfetti. Bu buluş, sağlık sisteminde önemli bir yere sahip olacak gibi görünüyor. NHS Blood and Transplant, Bristol Üniversitesi ve NHSBT Uluslararası Kan Grubu…