#MD-65

[roostro]

This flight is brought to you by McDonnell-Douglas

McDonnell-Douglas

"We got acquired by Boeing, so we could take over their Engineering & Safety and cut corners"

[trashygayspooder]

WAITING IN LOBBY!!!!

Jsgejsgejsbwgejsjsgdjsbshekafakanafysksngeusienejalanshismsbeislwnfucktrumpflaminghotcheetosguineapigswontshutupstarryslytherienyouremissingoutlol!!!

SOOOOOO FUCKING EXCITED EEK!!!

46k people, 12 minutes

Got the plush babies and the guinea pigs to keep me company

If Cyn dies meh whole family will know, cause you're gonna be able to hear me in Australia

[oddlittlestories]

Do I NEED to rewatch all of s1-4 + “Wilson” to understand it through the lens of Wilson / Spencer’s recent post on 97 seconds

before continuing on in HH:Reprise

in order to make sure I nail his & House’s portrayal in HH:Reprise?

No, no I don’t.

I don’t.

I do not.

This is NOT in the spirit of the “make it finished” > “make it better” poll

[the-mighty-e]

Last Marionetta drawing before 65 releases!!

I did the background with, like, 0 effort, I didn't want to do it at all 😭😭😭

IT HAS NO DEPTH LOOK AT THE CARPET AAA 😭 I hate detailed background

But drawing drunk eepy Julia cuddling on Sahed's lap was the highlight of it all and I'd do it again a million times

My next Marionetta drawing will be about ep 65 I'm sure

I'm also doing sum md drawings so I'll be back with that too my beloved md fans

[covid-safer-hotties]

Also preserved in our archive

Since older adults have been more severely affected by acute COVID-19, researchers have hypothesized that older adults may have worse long COVID symptoms as well. But according to new research published in the Annals of Neurology, an official journal of the American Neurological Association, Northwestern Medicine researchers found on an average of 10 months after COVID-19 onset, younger (ages 18-44) and middle-aged (ages 45-64) adults had worse neurologic symptoms of long COVID than adults 65 and older. Symptoms included headache, numbness and tingling, problems with smell and taste, blurred vision, depression, anxiety, insomnia, fatigue and a decrease in cognitive function. These symptoms occurred regardless of if the patient had mild or severe COVID-19 infections.

“While deaths from COVID-19 continue to decrease, people still get repetitive infections with the virus and may develop long COVID along the way,” said Igor Koralnik, MD, chief of neuroinfectious diseases and global neurology at Northwestern Medicine, who oversees the Neuro COVID-19 Clinic and is the co-director of the Northwestern Medicine Comprehensive COVID-19 Center. “Long COVID is causing an alteration in patients’ quality of life. Despite vaccinations and boosters, about 30 percent of COVID patients develop some long COVID symptoms. These findings have an immense public health impact, given that long COVID significantly contributes to the leading global burden of disability and disease caused by the neurological disorders.”

STUDY HIGHLIGHTS

· The study included the first 1,300 patients at the Northwestern Medicine Neuro COVID-19 Clinic with neurologic long COVID symptoms between May 2020 and March 2023.

· Among those patients, 200 had been previously hospitalized for severe COVID-19 pneumonia while the rest had mild initial COVID-19 symptoms and never required hospitalization.

· The study is a first-of-its-kind to look at the neurologic symptoms of long COVID over an adult lifespan.

· The goal was to determine if the neurologic symptoms of long COVID affect adults differently based on their age group.

“The impact of long COVID is causing disproportionate morbidity and disability in younger adults in their prime who provide much of the workforce, productivity and innovation in our society,” Dr. Koralnik said. “This may have a negative impact on the economy and cause additional burden on the health care system. This study highlights the importance that people of all ages suffering from Long COVID should be provided with the necessary treatment and rehabilitation services to alleviate their symptoms and improve their quality of life.”

To date, the Neuro COVID-19 Clinic has treated more than 2800 long-haulers from 44 states. For more information, visit nm.org and to schedule an appointment, please call 312.695.7950.

Studly link: onlinelibrary.wiley.com/doi/10.1002/ana.27128

[yumeka-sxf]

There were two panels related to Spy x Family at Anime Expo this year, with the first on Day 1 being Toho Animation's panel featuring both Spy x Family and Kaiju No.8.

The panel started with the SxF portion, with the special guests being the series director, Kazuhiro Furuhashi, and the CODE: White director, Takashi Katagiri. They also had the six SxF ThreeZero figures on the stage with them 😀

The MC asked them some questions, like what their favorite scenes were from their respective works and who their favorite character is. They also showed behind-the-scenes footage of both the Loid/Fiona tennis match in season 1, and Yor's fight scene against Type F in the movie. We got to see both of these scenes in rough animatic sketch form and then in line art form, which was pretty cool (it wasn't clear if photo/video was prohibited at this panel, but I didn't want to risk it by being caught blatantly recording these exclusive clips, lol). Then they showed off some of Anya's unused outfits from the movie.

At the end, they showed this original illustration by Kyoji Asano, made specifically for this event 😁

And that was it for the SxF part of the panel before they moved on to Kaiju No.8...and to be honest, it kinda overshadowed the SxF part, mostly because it featured two of the main Kaiju No.8 voice actors, one of which was extremely hilarious and charismatic. Plus there were a lot more segments compared to the SxF part. The interview with the guests seemed longer, they did three live voice overs, showed a pre-recorded special message from the band that performs the Kaiju No.8 opening, and then they took a group photo with the audience (and maybe something else that I'm forgetting). It seemed like the SxF part took up about 35% of the panel's time while Kaiju No.8 took up 65%. Not sure why it felt so unbalanced, but it was still fun.

Next was the panel on Day 3 for Production IG and their related studios WIT and Signal MD. Heads of each studio were there, including George Wada from WIT. Photo/video wasn't allowed once the panel started, but it basically consisted of an interview with the different guests, then trailers/teasers for their upcoming projects, then a Q&A session.

WIT is the studio that makes SxF, so I was hoping for any news about season 3, specifically if WIT would be more involved with it than they were with season 2. For those who don't know, season 1 of SxF was made by both WIT Studio and Cloverworks. But when they decided to make both season 2 and the movie in 2023, they split up the work, with WIT focusing on the movie while Cloverworks did pretty much all the work on season 2 (which is why the animation in season 1 and season 2 looks a bit different). According to this tweet, the official staff listing for season 3 is the same as season 2, meaning WIT will once again have little involvement. But despite this, they had a slide during the presentation with the season 3 promo image (preceded by the CODE: White teaser trailer, which made the crowd go wild - glad there were lots of SxF fans in the audience!) George Wada also said in regards to season 3 that they're "working hard on it."

I wanted to confirm during the Q&A if WIT would again take a backseat during season 3's production as well, but unfortunately the panel only had a few minutes left when it was close to my turn, and then they opted to pick a few random people in line for their last questions (which I thought was kind of unfair). Guess we'll just have to wait and see if anything changes with that staff listing once we get closer to season 3's release.

Overall, while Takuya Eguchi's appearance at last year's AX was more fun, it was still cool to attend this year's SxF-related panels as well. Hopefully season 3 will either be airing or close to being released at next year's AX, so we'll have even more SxF events!

[audiart]

Hi I'm Audi! I draw a lot. Interests: TADC, Murder Drones, RWBY, Animaniacs/Looney Tunes, The Magnus Archives, Dreamworks Trolls. Drawing is just a hobby of mine, so thank you for your patience. See below for FAQ, Emote server link, etc.

Animaniacs Emote server: https://discord.gg/Ma4tJSsvkf Been making some silly Animaniacs emotes in my free time! There are about 65 in this server + room for more later. Enjoy! FAQ:

╚═ What is MD Post Series?

Literally just my headcanons for what happens after Episode 8! The tag for it is #MD Post Series.

╚═ Do you take commissions? That depends on the request. Please send me a message so we can discuss further! Here is my pricing and TOS.

╚═ Can you draw my OC? In a commission, sure!

╚═ Any story plans? Nope, just yelling my headcanons into the void for now.

╚═ Any boundaries? None personally. I am OK with gore, NSFW, angst, violence, etc. Just be sure it is tagged/TW'd appropriately, as not everyone is OK with that content. I'd also like to see, so please tag me lol

╚═ Can we create fanart/fics/content? Can we dub or fancam? Yes of course, go wild!! Please tag me; I'd love to see all of it!

╚═ Is NSFW allowed? So long as it's marked appropriately. Also tag me I wanna see 👀💕

╚═ Can I ship the characters, self-ships, or OC x Canon? Do whatever u want?? idc Personally, I'm a Nuzi, Nuziv, EnVy, and Full Company shipper.

╚═ Fanfic recs?

Ad Astra Per Aspera https://archiveofourown.org/series/3677698 THE series of all times I adore the ping communication between Solver drones and the way everyone is written, the character development with Nori and Khan and so many little details.

The Brightest Candle Burns the Quickest https://archiveofourown.org/works/59797198 Yuri Vuzi slow burn enemies to lovers save me,,,

Kenosis https://archiveofourown.org/works/48450220 The holy grail of V character study. PLEASE PLEASEEE READ IT.

[shamebats]

House MD is 5% about the medical mysteries, 30% about the drama and 65% about getting to watch girls & women get a proper diagnosis because the doctor didn't think "it's just stress/anxiety/hormones" was a good enough answer

[dragonagitator]

So many of the newer House MD fans are shocked by House's casual racist, sexist, homophobic, etc. remarks and microagressions, and all I can think is... did y'all forget that House is literally a Baby Boomer?

I know that you are seeing a 45-year-old man on your screen, but you should not expect Xennial values and behaviors from that man because the show is 20 years old. House was born in 1959. He would be 65 now.

So yeah, next time House shocks you by saying something offensive or making a joke that really didn't age well, just think "okay boomer" and move on. No need to twist yourself up in knots trying to analyze or explain it away -- his generation was just Like That.

[eternal-echoes]

“To be fair, critics are correct that it is an oversimplification to speak of a "male brain" versus a "female brain." A close examination reveals extensive overlap in the structures and functions of the brains of men and women. Like their bodies, the brains of males and females have much in common, and much that is distinct.(32) Therefore, rather than speaking of a male or female brain, it is more precise to speak of the brain of a male or female. It is the person who is sexually dimorphic, not one's brain itself.

However, there are also profound sexual differences in the brain.(33) Whereas males have a greater number of white matter connections running from the front to the rear of their brain, women have more connections between the two hemispheres.(34) High levels of fetal testosterone results in a smaller corpus collosum in brains of men, which serves to transmit information from one side of the brain to the other.(35)

When performing identical activities, different regions of the brain are activated, based upon one's sex. For example, a specific region of the left brain is activated during speech for males, whereas women experience activation in different regions on both sides of the brain.(36) This explains why men take longer to recover speech following a stroke.(37) It also explains why a man might become mute after being injured on the left side of his head, whereas a woman struck in the same location is likely to keep on talking!(38)”

-Jason Evert, Male, Female, or Other: A Catholic Guide to Understanding Gender

—

Work cited:

32) Cf. M. Hines, "Sex-Related Variation in Human Behavior and the Brain," Trends in Cognitive Science 14:10 (2010), 448-56; M. Hines, "Gender Development and the Human Brain," Annual Review of Neuroscience 34 (2011), 69-88; McCarthy, Sex and the Developing Brain; Marianne J. Legato, MD, ed., Principles of Gender-Specific Medicine: Gender in the Genomic Era, 3rd ed. (Amsterdam: Academic Press, 2017).

33) Cf. Larry Cahill, "His Brain, Her Brain," Scientific American (October 1, 2012).

34) Cf. M. Ingalhalikar et al., "Sex Differences in the Structural Connectome of the Human Brain," Proceedings of the National Academy of Sciences of The United States of America 11:2 (2003), 823-828; Larry Cahill, "Fundamental Sex Difference in Human Brain Architecture," Proceedings of the National Academy of Sciences of the United States of America 111:2 (2014): 577-578.

35) Cf. Glezerman, Gender Medicine, 64.

36) Cf. B. Shaywitz, et al. "Sex Differences in the Functional Organization of the Brain for Language," Nature 373 (2004), 607-609.

37) Cf. D. Kent et al., "Sex-Based Differences in response to Recombinant Tissue Plasminogen Activator in Acute Ischemic Stroke," Stroke 36 (2005), 62-65.

38) Cf. B. and A. Pease, Why Men Don't Listen & Women Can't Read Maps, 65.

—

For more recommended resources on gender dysphoria, click here.

[thequiver]

Who is.... Ralph Dibny | The Elongated Man? - A Reading Guide

Ralph Dibny is a powered superhero from DC Comics first introduced in 1960. Ralph gains his ability to stretch his body to comic proportions as a result of his chronic ingestion of what is basically an essential oil. Ralph's hero work is largely based out of Opal City (which is kind of a stand-in for Baltimore, MD). Ralph is best known for his membership with the Justice League of America, Justice League Europe, and the Croatoans. Ralph is a devoted husband to his wife Sue, has his own exhibit at the Flash Museum, and is one of, if not the best detective in detective comics!

A selection of my favorite Ralph Dibny comics can be found in chronological order under the cut If you're interested in a full list of Ralph's appearances, please dm me and I'm happy to send you scans of a of my handwritten list!

The Flash (1959) #112, 115, 119, 124, 130, 134, 138 Detective Comics (1937) #328-345 Justice League of America (1960) #51 The Flash (1959) #206, 208, 210, 212 Justice League of America (1960) #100, 102, 105-106, 109-114, 116-121, 128-129, 131-134 Detective Comics (1937) #465-466, 468 Justice League of America (1960) #142-143 The Flash (1959) #252-253 Justice League of America (1960) #159-160, 210-212 (flashbacks), 161-168, 179, 181-183, 186-188 Detective Comics (1937) #500D The Flash (1959) #296 Justice League of America (1960) #189-191 The Brave and the Bold (1955) #177 Justice League of America (1960) #197-200 The Flash (1959) #323-325, 327-329 Justice League of America (1960) #226-227, Annual 2 (1984), 233-239 The Flash (1959) #341, 349 DC Retroactive: JLA - The 80's (2011) #1 <- chronologically this is where the story goes even if the issue is from 2011 Secret Origins (1986) #30

From here we really enter into Ralph's Justice League Europe era, so I'm separating the out a little bit

Justice League International (1987) #24 Justice League Europe (1989) #1-9 The Flash (1987) #35 Justice League Europe (1989) #10, 13-19, Annual 1, 20-21 The Flash (1987) #48-49 Justice League Europe (1989) #25-29 Justice League America (1989) #54 Justice League Europe (1989) #30 Justice League America (1989) #55 Justice League Europe (1989) # Annual 2, 31-33 Justice League America (1989) #58 Justice League Europe (1989) #34-35 Justice League Quarterly (1990) #6 Justice League America (1989) #60 Justice League Europe (1989) #36 Elongated Man (1992) #1-4 Justice League Europe (1989) #37-40 Green Lantern (1990) #25 (set during JLE #40) Justice League Europe (1989) #41-42, Annual 3, 43-503 Justice League Quarterly (1990) #9

Justice League International Take 2 through to Zero Hour

Justice League Task Force (1993) #1 Justice League International (1993) #51, Annual 4, 53-57 Justice League Task Force (1993) #10-12 Justice League America (1989) #89 Justice League Task Force (1993) #13 Justice League International (1993) #65 Justice League Task Force (1993) #14 Justice League International (1993) #66-67 Justice League America (1989) #92 Justice League Task Force (1993) #16 Justice League International (1993) #68 Zero Hour: Crisis in Time (1994) #1, 3

Post Zero Hour through to 52. This period of comics contains the highly controversial Identity Crisis, which centers around the death of Ralph's wife, Sue.

Starman (1994) #56, 61-63, 65, 67-68, 70-73, 75, 80 Doom Patrol (2001) #4-6 Formerly Known as the Justice League (2003) #1-6 Identity Crisis (2004) #1-7 52 (2006) #1-2, 4-5, 7-8, 11-13, 18, 21, 24-25, 27, 31-33, 39, 41-42, 52

After 52, Ralph comes back as a ghost for a few issues and later as a black lantern during Blackest Night but tbh I didn't enjoy those much at all so they're not included

[rjzimmerman]

From what I can read online without a paywall block, US medical schools are moving in the direction of requiring or offering courses on climate change. I'm copying this directly from my Duck Duck Go search results:

The number of medical schools in the United States that include climate change in their curriculum has been increasing, with 65% of MD-granting schools requiring or offering courses on the topic in 2022.  A survey by the Association of American Medical Colleges (AAMC) found that the percentage of medical schools with climate change in their curriculum increased from 27% in 2019–2020 to 55% in 2021–2022, and then to 65% in 2022. 

Excerpt from this EcoWatch story:

A network of universities across Europe has launched an initiative to train medical students on climate change-related illnesses as well as provide education on more sustainable healthcare.

The initiative includes 25 universities that have formed the European Network on Climate & Health Education (ENCHE), which will incorporate climate change education into the existing curriculum. The goal is to better prepare students to treat humans facing health disparities linked to climate change as well as to improve the sustainability of the healthcare system.

“From the spread of infectious diseases to increasingly deadly heatwaves, the health impacts of climate change are becoming ever more dangerous,” Iain McInnes, co-chair of ENCHE and vice principal and Head of College of Medical, Veterinary and Life Sciences at the University of Glasgow, said in a statement. “As educators, it is our responsibility to ensure that the next generation of doctors, health professionals and medical leaders have the skills they need to face these challenges and can provide patients with the best care possible.”

The network will be led by the University of Glasgow and supported by the World Health Organization (WHO), and universities from Belgium, France, Germany, Ireland, Italy, Poland, Portugal, Slovenia, Sweden, Spain, Switzerland and the UK will be involved in ENCHE.

Other health organizations, part of the Sustainable Markets Initiative Health Systems Task Force, will provide additional support to ENCHE. The network will serve as a regional hub for the Global Consortium on Climate and Health Education (GCCHE) at the Columbia University Mailman School of Public Health, with GCCHE providing collaboration and expert support for the initiative.

ENCHE has a goal to train 10,000 or more medical students on treating climate change health impacts in the first three years of the program. According to the University of Glasgow, there is not a consistent curriculum in medical schools that teaches on the links between climate change and health impacts.

This training could help save many more lives, as human health becomes increasingly vulnerable to the impacts of climate change. According to the WHO, about 99% of humans globally are exposed to air quality below WHO standards, while more than 7 million people die from air pollution-related health impacts. Rising heat is another concern, with heat-related deaths expected to triple by 2050 in a business-as-usual scenario. 

[paperanddice]

Eleinomae

Known as marsh nymphs, eleinomae are quite cruel fey. Despite their moniker, they are often found in rivers and similar bodies of water as well as marshes. They are quite a bit more dangerous than the naiads that they share an environment type with, able to bond with larger bodies of water than naiads, and will bully their weaker sisters when they have the opportunity. They will also use the reputation of naiads as more benevolent and friendly to prey on further victims, luring in those who don't recognize the different kinds of fey. Using illusions and charms, they seduce travellers and lead them to their death, working with natural creatures, drawing the victim into water deeper and rougher than they can handle, or using their knives if they must to ensure that their new toy is added to their collection.

Most eleinomae have a graveyard of sorts, a place where the many bodies they've collected float among fields of water lilies. These bodies are the eleinomae's favorites, those who were an entertaining capture, or were particularly beautiful. If you follow the sound of mysterious singing in the marshes, you may find an eleinomae's graveyard as she sings to the dead, though doing so may be the last thing you ever do. These graveyards are often guarded by charmed allies or beasts the eleinomae has persuaded, and she will fight furiously to kill anyone who intrudes upon this territory.

Inspired by the Tome of Beasts 1, another of its murderous, beautiful women. This post came out a week ago on my Patreon. If you want to get access to all my monster conversions early, as well as access to my premade adventures and other material I’m working on, consider backing me there!

Pathfinder 2e

Eleinomae Creature 5 Medium, Amphibious, Fey, Nymph, Water Perception +11 Languages Common, Elven, Fey, Thalassic Skills Acrobatics +13, Deception +15, Diplomacy +13, Intimidation +13, Performance +15 Str +1, Dex +4, Con +3, Int +2, Wis +2, Cha +4 Aquatic Empathy The eleinomae can ask questions of, receive answers from, and use the Diplomacy skill with animals and plants that have the amphibious or aquatic trait. Items dagger, reed net (×3) AC 23; Fort +14, Ref +15, Will +15 HP 65; Weaknesses cold iron 5 River Dependent An eleinomae is bonded to a river or a section of marshland. If she is more than 300 feet away from it for 24 hours or more, she gains the weak adjustments until she returns. She can perform a 24-hour ritual to bond herself to a new body of water. Speed 25 feet, swim 25 feet Melee dagger +13 (agile, finesse, poison), Damage 1d4+5 piercing plus 1d6 poison Primal Innate Spells DC 23 ; 5th illusory scene; 4th mirage, suggestion (×3); 1st charm (×3); cantrips (3rd) figment, light Reed Net [1 action] Requirements The eleinomae is holding a reed net in two hands; Effect The eleinomae hurls her net to hamper a foe. She makes a ranged Strike (with a +13 modifier) against a Medium or smaller creature within 20 feet. On a hit, the target is flat-footed, takes a –10‑foot circumstance penalty to its Speeds, and is stupified 1. On a critical hit, the creature is instead restrained and stupified 3. The DC to Escape the net is 19. A creature adjacent to the target can Interact with the net to remove it from the target. Reed Walk The eleinomae isn't impeded by difficult terrain caused by undergrowth and water.

13th Age

Eleinomae 3rd level spoiler [humanoid] Initiative: +9 Poisoned Dagger Slice +8 vs. AC – 7 damage. Natural Even Hit: 6 poison damage. R: Reed Net +8 vs. PD (one nearby enemy) – 4 damage and the target takes a -1 penalty to MD (save ends). Natural 14+: The target is stuck and takes a -2 penalty to MD (save ends both). R: Charming Words +8 vs. MD (one nearby enemy) – The target can’t attack the eleinomae (save ends). This effect ends if the eleinomae attacks the target. Natural 14+: The target makes a single basic attack against a target within its range of the eleinomae’s choice. Natural 18+: The save to end the charming words effect is now hard (16+). Limited Use: 2/battle, can’t be used if an enemy is under the effects of this attack. Swimmer. Unfortunate End: If at any point there is only one player remaining in the battle, and they are under the effect of the eleinomae’s charming words, the encounter ends with a campaign failure as that character is brought under the eleinomae’s sway and can’t fight anymore. AC 18 PD 14 MD 17 HP 42

[most-screwed-by-writers-tourney]

Already got a list of the ships for the ULTIMATE fucked up ship tournament done. Hopefully will start it in two weeks or so. This is a list of the ships:

1. The Darkling and Alina, The Grisha Trilogy

2. Batman and The Riddler, The Batman 2022

3. stu and billy from scream

4. Vriska and Terezifrom homestuck

5. light and l from death note

6. Dirk Strider and Jake English from Homestuck,

7. Vio and Shadow Link from the Four Swords manga

8. Emilio Murkmere x Tobias Schenien from Ghost Eyes

9. Oswald x Ed from Gotham

10. Anna Croft/ Yu Junghyeok (orv)

11. Dimitri/Edelgard - Fire Emblem Three Houses

12. Will Graham and Hannibal, Hannibal

13. yoonbum x sangwoo, killing stalking

14. Starscream and Megatron, from the Transformers franchise

15. Mukuro Ikusaba/Junko Enoshima from Dangan Ronpa

16. Ladd Russo and Lua Klein from Baccano!

17. Daida and Miranjo from Ousama Ranking

18. Shizuo and Izaya from Durarara!!

19. theresa x otto, honkai impact

20. dorian x fem! inquisitor, dragon age

21. renee x huey from baccano

22. nanami x touga, revolutionary girl Utena

23. madoka and homura, puella magi madoka magica

24. (Ronan Lynch x Joseph Kavinksy) - The Raven Cycle

25. Seishirou and Subaru from Tokyo Babylon/X

26. Misaki/Satou, Welcome to the NHK

27. Bakugou and Deku (My Hero Academia)

28. Akito and Shigure, Fruits Basket

29. House and Wilson, House MD

30. Scarlet and Chase, I’m the Grim Reaper

31. Jong-woo and Moon-jo, Strangers from Hell

32. Moon-young and Gang-tae, It’s Okay to Not Be Okay

33. Medea and Helio, Your Throne

34. Celty and Shinra, Durarara

35. Akira and Ryo, Devilman

36. Yoshino and Kirishima, Raise wa Tanin Ga ii

37. Chateau and Ryang-ha, Love of Kill

38. Satoko and Shinpei, Hotaru no Yomeiri

39. Clarice and Hannibal, Silence of the Lambs

40. He Yan and Fu Shenxing, Who is the Prey

41. Cain/Owen from Promise of Wizard / Mahoyaku

42. Texas/Lappland from Arknights.

43. Jeongmin and Siyun, Dreaming Freedom

44. Han Chae-ah and Park Yunsu, Trapped

45. akane kurashiki/junpei tenmyouji from zero escape

46. Juri/Shiori (from Revolutionary Girl Utena)

47. Jackie/Shauna, Yellowjackets)

48. Cassandra/Rapunzel from the Tangled series

49. Damien and Elena from vampire diaries

50. Kristoph/Phoenix, Ace Attorney

51. Juice and Chibs, Sons of Anarchy

52. Utena/Anthy from the anime Revolutionary Girl Utena.

53. Cutthroat x Swindler, from Akudama Drive.

54. Yuno Gasai x Yukkiteru Amano from Mirai Nikki

55. Sal/Syakesan x Wadanohara from Wadanohara and the Great Blue Sea.

56. Jeremy and the SQUIP, Be More Chill

57. Ian Grimm and Poppy Li, Mythic Quest

58. Lestat de Lioncourt and Louis De Pointe du Lac, Interview with the Vampire

59. fuuma and kamui from clamp's x/1999

60. Victor and Eli, Vicious

61. Elisabeth and Der Tod, Elisabeth

62. Rudolf and Der Tod, Elisabeth

63. Veronica Sawyer and J.D, Heathers

64. Akechi Goro × Persona 5 protagonist (Akira Kurusu/Ren Amamiya)

65. Hondomachi and Fukuda, ID: Invaded

66. Harley Quinn and the Joker, DC

67. Christine and Erik, Phantom of the Opera

68. Lisa Reisert and Jackson Rippner, Red Eye

69. Valeta and Reinhart, I Failed to Oust the Villain

70. Light Yagami and Misa Amane, Death Note

71. Sumire and Hakubo, Toilet Bound Hanako Kun

72. Mika Harima and Seiji Yagiri, Durarara!!

73. Emma Wilson and Yohan Lee, My Deepest Secret

74. Sarah and Jareth, Labyrinth

75. Addie LaRue and Luc, The Invisible Life of Addie LaRue

76. Ja Yoon and The Nobleman, The Witch, Part One: Subversion

77. Makima and Denji, Chainsaw Man

78. Kyoko and Katsuya, Fruits Basket

79. Mrs. De Winter and Maxim, Rebecca

80. Mutsuki Tooru and Urie Kuku, Tokyo Ghoul

81. Victor and Elizabeth, The Dark Descent of Elizabeth Frankenstein

82. Constanta, Magdalena, and Alexei and Dracula, A Dowry of Blood

83. Ha-im and Geunhu, Never Ending Darling

84. Frank Cotton & Julia Cotton - Hellraiser (1987)

85. Yuki Cross & Kaname Kuran, Vampire Knight

86. Johann and Sasha, The Double Agent

87. Sian and Yul, Secret Alliance

88. Charlize and Dylan, The Taming of the Tyrant

89. Lin and Dosung, 340 Days

90. Makishima Shougo & Shinya Kougami from PSYCHOPASS.

91. Charlotte Willmore x Lizzie Wells, from The Perfection (2018).

92. “Hikaru”/Yoshiki from The Summer hikaru Died,

93. Dolph Laserhawk x Alex Taylor from Captain Laserhawk

94. Dolph Laserhawk x Rayman from Captain Laserhawk: A Blood Dragon Remix

95. Yuuji Itadori x Mahito from Jujitsu Kaisen

96. (luo binghe x shen qingqiu) from scum villain's self saving system.

97. Heaven Official's Blessing. Ships He Xuan and Shi Qingxuan.

98. Ives and Boyd from Ravenous 1999

99. Eve and Vilanelle, Killing Eve

100. Sephiroth/Cloud (FF7 Compilation)

101. Clary and Jace from the Mortal Instruments

102. Rika Sasaki/Yoshiyuki Terada, Cardcaptor Sakura,

103. Veralidaine Sarrasri/Numair Salmalín, from the Immortals Quartet

104. Eli/Oskar, Let the Right One In (2008).

105. Lavan Firestorm/Kalira, Brightly Burning

106. Lapis/Jasper (Steven Universe

107. PearlescentMoon/SMajor, the Life Series

108. Christine/Erik (Phantom Takarazuka)

109. The Brain/Julia (Animaniacs 2020)

110. Sterek, Teen Wolf

111. Jonathan Sims/Elias Bouchard, The Magnus Archives

112. Fyodor and Nikolai, Bungo Stray Dogs

113. Beatrice and Battler, Beabato, from "Umineko”

114. Father Paul/Riley Flynn; Midnight Mass

115. Edward Teach/Izzy Hands; Our Flag Means Death;

116. Batman/Joker

117. Cesare Borgia/Lucrezia Borgia - The Borgias

118. Dean/Sam Winchester from Supernatural

119. Vegas/Pete (Kinnporsche: The Series)

120. Hitori Uzune and Nanaki Kazuaki from Hatoful Boyfriends.

121. Lanze/Bluepool and Anan from Beauty and the Beasts

122. Blade and Dan Heng from Honkai Star Rail

123. Spike and Buffy, Buffy the Vampire Slayer

124. Isaac and Finn, I’m Dating a Psychopath

125. Lenore and Annabelle, Nevermore

126. Estelle and Khalid, From a Knight to a Lady

127. Layla and Matthias, Cry or Better Yet Beg

128. Hyuna and Luka, Alien Stage

129. Karuto and Lily, Dear my Living Dead

130. Andrew and Ashley Graves, Coffin of Andy and Leyley

131. Lydia Deetz/Beetlejuice, Beetlejuice

132. Harrow and gideon from gideon the ninth/Locked Tomb

133. Cathy x Heathcliff (Wuthering Heights)

134. Felix x Ollie (Saltburn)

135. Grace Chastity x Max Jaegerman, Nerdy Prudes Must Die

136. Mikoto and Haijin, Tsuiraku JK to Haijin Kyoushi

137. Eucenielle and Tes, I Hold the Tyrant’s Heart

138. Claire and Balt, The East Wind of the Altas

139. Usui and Misaki, Maid Sama

140. Sebastian Michaelis and Ciel Phantomhive, Black Butler

141. Dabi x Hawks from My Hero Academia

142. Alice “Daisy” Tonner/Basira Hussain, The Magnus Archives

143. Naruto and Sasuke, from Naruto

144. Byleth Eisner / Jeritza von Hrym from fire emblem three houses

145. Akira x keisuke from togainu no chi (nitro+chiral game)

146. Lucy Gray Baird and Coriolanus Snow, The Ballad of Songbirds and Snakes

147. Elias and Chise, The Ancient Magus Bride

148. Gendo and Yui Ikari, Neon Genesis Evangelion

149. Punpun and Aiko, Goodnight Punpun

150. Sang-hyun and Tae-ju, Thirst

151. Hawa and Adam, The Guy Upstairs

152. Satoru Fujnuma and Gaku Yashiro, Erased

153. Root and Sameen Shaw, Person of Interest

154. The Doctor and the master, Doctor Who

155. Juliette and Warner, Shatter Me

156. Ich and Mrs Danvers, Rebecca das Musical

157. Kokichi Ouma and Shuichi Saihara, Danganronpa V3

158. Roxy and Velma, Chicago

159. Griffith and Guts, Berserk

160. Creed and Train, Black Cat

161. Torso and Mutsuki, Tokyo ghoul

162. Vash and Knives, Trigun

163. Sweeney Tod and Mrs Lovett, Sweeney Tod

164. Kuroi and Mashiro, Thou Dhall Not Die

165. Amy and Nick, Gone Girl

166. India and Charlie Stoker, Stoker

167. Pig and Runt, Disco Pigs

168. Anakin and Padme, Star Wars

169. Chloe and Kairos, I Shall Kill That Sweet Devil

170. Jung and Seol, Cheese in the Trap

171. Anthy and Akio Ohtori, Revolutionary Girl Utena

172. Feyre and Rhysand, A Court of Thrones and Roses

173. Lelouch and Suzaku, Code Geass

174. Mikiya and Shiki, Garden of Sinners

175. Gatsby and Daisy, The Great Gatsby

176. Ivan and Till, Alien Stage

177. Sylar and Elle Bishop, Heroes

178. Helena and Demetrius, A Midsummer Night’s Dream

179. V and Rika, Mystic Messenger

180. Yukari and George, Paradise Kiss

[socialoutsider1a]

Robert Sean Leonard is from Westwood, New Jersey in the United States and his full name is actually Robert Lawrence Leonard. He's also been acting since 1981. He was born on February 28, 1969 and he's 55 years old. RSL is mostly famous for his roles in the 1989 movie, Dead Poets Society and as James Wilson in House MD. He is an actor who acts in TV and mostly theater, having even won a Tony Award.

Hugh Laurie is from Blackbird Levys, Oxfordshire in the UK and his full name is James Hugh Calum Laurie. He's been acting since 1981. He was born on June 11, 1959 and he's 65 years old. In addition to being an actor, HL is also a comedian, writer and musician, having first gained recognition in the UK as a member of the comedy double act, Fry and Laurie with his best friend, Stephen Fry. The two men have also worked together on various projects during the 1980s and 1990s, examples being the sketch comedy series, "A Bit of Fry and Laurie", the TV adaptation of "Jeeves and Wooster". From 1986 to 1989, HL appeared in three series of the period comedy series, "Blackadder". In the UK, he's famous for his work as a member of Fry and Laurie as well as Blackadder while in the U.S., HL is best known for playing Dr. Gregory House on "House MD". He's also won three Golden Globes.

Even though there's a seven year age gap betwen House and Wilson, in real life, HL is ten years older than RSL.

[covid-safer-hotties]

Also preserved in our archive (Daily updates!)

There've been a lot of studies showing vitamin D deficiency in people with mild to severe covid cases. A new meta-analysis probes into the possible connections and effects of vitamin D during acute covid infections.

By Dr. Liji Thomas, MD

New study suggests vitamin D supplementation may lower ICU and intubation rates in COVID-19 patients, with greater benefits seen in older and severe cases.

The impact of vitamin D on the progression of COVID-19 remains uncertain. A recent meta-analysis in Nutrients reviewed studies on vitamin D supplementation in COVID-19 patients to assess its effectiveness in reducing disease severity across various health metrics.

Why is vitamin D important? Vitamin D is essential for bone health, but its influence extends far beyond, as its receptor is present in all nucleated human cells. This receptor regulates nearly 4% of human genes, impacting many physiological processes, including cancer development, muscle function, cardiovascular health, glucose balance, and immune response to infections and autoimmune reactions.

With the onset of the SARS-CoV-2 pandemic, there was significant interest in whether vitamin D could reduce the severity or spread of COVID-19. Vitamin D plays a role in immunity by lowering the release of pro-inflammatory cytokines, boosting antimicrobial peptides, supporting epithelial barriers, and modulating T-cell activity—mechanisms that may help prevent the severe hyperinflammation associated with critical COVID-19 cases and high mortality.

This study investigates the protective effects of vitamin D supplementation during COVID-19, used alongside standard treatments like glucocorticoids, anticoagulants, and antivirals, as recommended in current care guidelines.

About the study The researchers included 21 randomized controlled trials (RCTs) and eight analytical studies in the meta-analysis. Of these, mortality rates were examined in 19 RCTs and seven analytical studies, intensive care unit (ICU) admissions in 14 and five, respectively, intubation rates in nine and three, respectively, and the length of hospital stay (LOS) only in RCTs.

Vitamin D dosage varied considerably between studies, both in intervention and control groups.

Vitamin D and ICU admissions In the randomized controlled trials (RCTs), vitamin D supplementation demonstrated a stronger protective effect at higher doses compared to lower doses. Specifically, higher doses were associated with a 63% reduction in ICU admission rates compared to lower doses.

ICU admissions decreased by 57% among patients aged 65 or older and by 44% among those under 65. Patients with severe disease did not show a significant response to vitamin D, while those with non-severe disease experienced 33% fewer ICU admissions.

Intubation rates Intubation rates fell by 50% in RCTs. The lack of effect in analytical studies may have been because they were carried out only in non-severe older COVID-19 patients and were limited in number.

The tendency towards significance strengthens the hypothesis of the benefit of vitamin D in reducing the need for intubation during COVID-19.

Mortality rates Mortality rates showed significant differences in the vitamin D supplementation group but only in analytical studies, with a fall of 55%. This might indicate a tendency to bias in analytical studies.

Despite the overall lack of significance, age-stratified analysis of the RCTs showed a 42% reduction in mortality in older patients but not those <65 years. The authors suggested that the overall analysis might have failed to reveal these more granular effects.

Another interesting effect was that vitamin D supplementation had a more marked mortality-reducing impact in the early months of the pandemic, up to May 2020, than later on.

Finally, the most ill patients had a 50% mortality reduction benefit, but not the less severely ill patients. Thus, mortality analyses in the RCTs present a complex picture, with significant protective effects observable in some subgroups but not in the overall analysis.

LOS Among non-severe COVID-19 patients, vitamin D supplementation was associated with a -0.95-day difference in hospital length of stay. Potential benefits could exist in other groups, but this awaits validation from future research.

The variations between studies should be interpreted as accounting for the forms of vitamin D in use, such as calcifediol or cholecalciferol.

The latter is faster-acting than the former, which may make a difference in acute severe COVID-19, especially as evidence indicates that active vitamin D is used up in the acute response to the infection.

However, broad differences were noted across the studies, including baseline vitamin D levels, dosages, and duration of symptoms before vitamin D supplementation. Still, the findings agree with some previous analyses, with a more nuanced conclusion.

Conclusions The findings do indicate that vitamin D supplementation could be of benefit in COVID-19 treatment, reducing ICU admissions, mortality, and intubation requirements. All studies showed fewer ICU admissions in the intervention group.

“The differing effects based on age, disease severity, and possibly baseline vitamin D status highlight the need for a nuanced approach to vitamin D supplementation in COVID-19 management.”

The greatest effect seems to be in reducing ICU admissions. Still, with differences in the evidence across various patient subgroups and for different outcomes, there is a need for larger trials with a better design that adjusts for baseline vitamin D levels and uses standardized dosages and regimens, as well as compensating for patient characteristics.

Journal reference: Sartini, M., Puente, F. D., Carbone, A., et al. (2024). The Effect of Vitamin D Supplementation Post COVID-19 Infection and Related Outcomes: A Systematic Review and Meta-Analysis. Nutrients. doi: doi.org/10.3390/nu16223794. www.mdpi.com/2072-6643/16/22/3794.