#this sounds interesting
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I can boop myself?????
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New Oscar Isaac project alert with the creators behind Severance and All Quiet on the Western Front! ❤️
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#this sounds interesting#thinky thoughts#gen x annoyed with all the rest of you t shirt#the Orville is an amazing show BTW#American Dad has gotten beautifully philosophical#let me watch my trash shows in peace#because people hate Seth MacFarlane but he's a sweetheart
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Did you hear about procreate coming out with another app? procreate Dream.
👀
👃🏻
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Me interested.
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Tofu Anon:
-The True World War-
Sagau!Genshin: Our Grace ^.^
My Fictional Universe: No, our highness. ^.^*
Mama Tofu: I think the (bleep) not. ^_^
Hold on a minute-
"The True World War" 👀
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#writing#writer things#writeblr#meme#aaahh#writing meme#heeeellpppp#id in alt text#can't continue being in progress if the foundation isn't sound anymore#this is about static house as something new and more interesting just came to me abd makes more sense too but aah to rework it all#i must i feel i must#it's happened with others too of course but stilll
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A new treatment combining ReCET and semaglutide could eliminate the need for insulin in type 2 diabetes, with 86% of participants in a study no longer requiring insulin therapy. The treatment was safe and well-tolerated, and further trials are planned to confirm these results.
Groundbreaking research presented at UEG Week 2024 introduces a promising new treatment approach for type 2 diabetes (T2D) that has the potential to greatly reduce or even eliminate the need for insulin therapy.
This innovative approach, which combines a novel procedure known as ReCET (Re-Cellularization via Electroporation Therapy) with semaglutide, resulted in the elimination of insulin therapy for 86% of patients.
Globally, T2D affects 422 million people... While insulin therapy is commonly used to manage blood sugar levels in T2D patients, it can result in side effects... and further complicate diabetes management. [Note: Also very importantly it's fucking bankrupting people who need it!!] A need therefore exists for alternative treatment strategies.
Study Design and Outcomes
The first-in-human study included 14 participants aged 28 to 75 years, with body mass indices ranging from 24 to 40 kg/m². Each participant underwent the ReCET procedure under deep sedation, a treatment intended to improve the body’s sensitivity to its own insulin. Following the procedure, participants adhered to a two-week isocaloric liquid diet, after which semaglutide was gradually titrated up to 1mg/week.
Remarkably, at the 6- and 12-month follow-up, 86% of participants (12 out of 14) no longer required insulin therapy, and this success continued through the 24-month follow-up. In these cases, all patients maintained glycaemic control, with HbA1c levels remaining below 7.5%.
Tolerability and Safety
The maximum dose of semaglutide was well-tolerated by 93% of participants, one individual could not increase to the maximum dose due to nausea. All patients successfully completed the ReCET procedure, and no serious adverse effects were reported.
Dr Celine Busch, lead author of the study, commented, “These findings are very encouraging, suggesting that ReCET is a safe and feasible procedure that, when combined with semaglutide, can effectively eliminate the need for insulin therapy.”
“Unlike drug therapy, which requires daily medication adherence, ReCET is compliance-free [meaning: you don't have to take it every day], addressing the critical issue of ongoing patient adherence in the management of T2D. In addition, the treatment is disease-modifying: it improves the patient’s sensitivity to their own (endogenous) insulin, tackling the root cause of the disease, as opposed to currently available drug therapies, that are at best disease-controlling.”
Looking ahead, the researchers plan to conduct larger randomized controlled trials to further validate these findings. Dr. Busch added, “We are currently conducting the EMINENT-2 trial with the same inclusion and exclusion criteria and administration of semaglutide, but with either a sham procedure or ReCET. This study will also include mechanistic assessments to evaluate the underlying mechanism of ReCET.”
-via SciTechDaily, October 17, 2024
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Note: If it works even half as well as suggested, this could free so many people from the burden of the ongoing ridiculous cost of insulin. Pharma companies that make insulin can go choke (hopefully).
#would be super interested to hear from people with expertise in the area about how this sounds#obviously it's a small sample size#but they're going to do more trials#and LOOK at that effectiveness rate#insulin#diabetes#healthcare#medicine#diabetic#type 2 diabetes#public health#medical news#good news#hope
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Sex positivity is also about not calling Ace people prude and using virgin as an insult 👍 hope that helps
#sex positivity is also respecting sex lives that dont look like yours#or lack thereof#and insulting people by saying they dont fuck make you sound stupid <3#im sorry i just cant take people who use their sex lives as a flex seriously its just not my thing!#like yea having lots of kinky sex is cool but not having sex and not being interested by sex is also cool#one is not better than the other the human experience is just very varied and diverse#its normal you wont understand everyone your brain isnt even made to comprehend how many human there are in the world#but we should all have spaces to navigate our sex lives as we wish even if that means interacting with sex as a subject as little as possibl
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... does this mean that whimsun has mini-boss type battle?? like every time u fight them, it's feels like mod "every mob is sans", but on steroids w/out steroids (yes, at the same time)?????
I drew more of them! They are so silly
And for anyone who might be interested, This is sort of an AU of mine that I like to call FragileTale!
The premise is similar to underswap tbh, but instead of reversing the characters' roles it actually reverses each one's status
So, everybody that is strong, becomes weak
And everybody weak, becomes stronger
And the name of the au, fragiletale, is based on that - since most of the monsters would become weak
And the LV mechanic changes a bit as well, bc since in the original game we start as LV 1; in here the human starts already at LV 19. It starts being the threat that the human can be to the monsters But, As long as the human decides to become friends and help others, their Violence Points will decrease - since they will start learning how to be kind
But anyways this is a cooking idea yet!! Thx you for your time!❤️🩹
#reblog#this sounds interesting#au based on game mechanic yoooooo#i wanna know more 👁👁#👁👁👁👁👁👁👁👁#undertale au
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Dc x Dp Prompt #6
“I’m a twin”, Damian said one night. He could feel the narrowed eyes of his family drilling holes on his back in disbelief. Not that he could blame them. Damian had never so much as implied being raised with a companion, much less a sibling.
“I had a brother”. Damian paused to recollect himself. He had not said his brother’s name out loud in over 8 years.
“His name was… Danyal”. Damian hated the way his voice wavered, but he could not help it. Danyal was everything to him, his other half. Their heart beat as one and when one heart stopped beating, the other one died with it. At least until his family put his heart on metaphorical life support without ever realizing.
“Where is he now?” His father asked, voice filled with knowing grief and a hint of betrayal. It had in fact been 6 years since Damian first showed up on his doorstep.
“Up there”. All eyes shifted towards the specific star he was pointing to. ��Right before he died, he promised me he’d guide me from the stars. Unfortunately, the stars are not visible in Gotham, so my brother is unable to be of much help unless I leave the city.”
“Your brother is Polaris, the North Star?” Tim questioned warily, most likely in attempts to not offend him. Damian was aware of how stupid it sounded, but Danyal had promised, and his brother never broke his promises.
“Yes. Danyal is with the stars now, just as he always wanted”
#dc x dp#dp x dc#dpxdc fanfic#dc x dp prompt#dp x dc prompt#dc x dp crossover#dp x dc crossover#ghost king danny#demon twin au#danyal al ghul#batpham#they are not in Gotham at the time of this conversation#I’m thinking they’re visiting the Kent’s on their farm but tbh as long as the stars are visible it can be anywhere#Danny did in fact reincarnate as Polaris#sort of#Polaris is more of a title the Realms gave him the day he was crowned#he is the star meant to guide them through a new era#or something like that#But Damian does look up at the stars for guidance whenever he sees them#and before he knows it he’s accidentally begun praying to Danny#it’s his coping mechanism for being unable to speak about him to anyone#but back to Danny - he regained the memories of his time as Danyal Al Ghul when he died in that portal and became a halfa#well it was more he regained the memories of ALL his previous lives but his most recent one holds a special place in his heart#if only because he knows his brother is still alive on whatever earth he was born on#as bad as it sounds Danny can’t wait until he gets to reunite with Damian#he hopes Damian forgives him for not guiding him though#fun fact! Danny was once known as the god Dan-El in one of his previous lives#he’s ALSO the reincarnation of the Greek Titan Astraeus (and he’s pretty sure Dani is his daughter Astraea)#his previous lives are all so interesting (he still can’t believe he was raised an assassin or that he was a god in multiple lives)#but in all honesty it’s even weirder feeling so old and so young at the same time
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i love when words fit right. seize was always supposed to be that word, and so was jester. tuesday isn't quite right but thursday should be thursday, that's a good word for it. daisy has the perfect shape to it, almost like you're laughing when you say it; and tulip is correct most of the time. while keynote is fun to say, it's super wrong - i think they have to change the label for that one. but fox is spot-on.
most words are just, like, good enough, even if what they are describing is lovely. the night sky is a fine term for it but it isn't perfect the way november is the correct term for that month.
it's not just in english because in spanish the phrase eso si que es is correct, it should be that. sometimes other languages are also better than the english words, like how blue is sloped too far downwards but azul is perfect and hangs in the air like glitter. while butterfly is sweet, i think probably papillion is more correct, although for some butterflies féileacán is much better. year is fine but bliain is better. sometimes multiple languages got it right though, like how jueves and Πέμπτη are also the right names for thursday. maybe we as a species are just really good at naming thursdays.
and if we were really bored and had a moment and a picnic to split we could all sit down for a moment and sort out all the words that exist and find all the perfect words in every language. i would show you that while i like the word tree (it makes you smile to say it), i think arbor is correct. you could teach me from your language what words fit the right way, and that would be very exciting (exciting is not correct, it's just fine).
i think probably this is what was happening at the tower of babel, before the languages all got shifted across the world and smudged by the hand of god. by the way, hand isn't quite right, but i do like that the word god is only 3 letters, and that it is shaped like it is reflecting into itself, and that it kind of makes your mouth move into an echoing chapel when you cluck it. but the word god could also fit really well with a coathanger, and i can't explain that. i think donut has (weirdly) the same shape as a toothbrush, but we really got bagel right and i am really grateful for that.
grateful is close, but not like thunder. hopefully one day i am going to figure out how to shape the way i love my friends into a little ceramic (ceramic is very good, almost perfect) pot and when they hold it they can feel the weight of my care for them. they can put a plant in there. maybe a daisy.
#warm up#writeblr.#i am not going to personally comment on the pineapple debate#some things are too big for me.#maybe we could have everything on earth choose their own names.#wouldn't that be fun#it is a creative writing exercise. okay. ily#''why only these languages?'' ..... bc i dont know every language#sorry :(#PLEASE leave me comments about what words u think are correct. i love learning them#btw! this isn't saying these are the most BEAUTIFUL words for it... just the words that are the most CORRECT#like i quite like the word ''keynote'' as mentioned. it's got a lot of fun sounds in it.#but it is not CORRECT.#''gloaming''' is interesting and fun and poetic but it is NOT correct . evening is MORE correct#but less beautiful.#does that make sense?
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Reading (listening to, as Homer intended) the Iliad making me go oh. Ohhh. I should have done this before I read Gideon the Ninth. I get it now.
Particularly thinking now about the tidbit that in early drafts, our beloved gray-eyed Necromancer Warden of the Sixth House was named Diomedes Sextus. For Diomedes, king of Argos, young, brave, noble, heroic. Favorite fighter of Athena, bestest friend of Odysseus. And, notably, fought gods and—well he didn’t win exactly. But he got them good.
And specifically, he fought and wounded Aphrodite; Aphrodite, who is also called Cytherea.
And then of course Tamsyn Muir said she decided to change his name so she could make the Sex Pal joke.
Palamedes is a less heroic, less fondly remembered character in the Trojan War, but according to Plato, he unrelatedly invented both number and the alphabet, so you keep that connection to scholarship even if that’s not the first association with him. More interestingly, imo, there’s also an Arthurian Knight of the Round Table named Palamedes, best known for his unrequited love for Isolde (and his apparent ultimately gracious acceptance of her choosing Tristan).
I think this is actually a super interesting shift in thematic naming focus: from favored-of-Athena, fought-gods-and-wounded-them to unrequited heterosexual love, but didn’t act like a dick about it.
Also y’know. Sex Pal
#I also wonder when this happened because there’s the shared ‘am’ sound in Camilla and Palamedes that Muir pointed out#That she was going for with her necromancer-cavalier pairs#Abigail and Magnus have an ag/ga element; Cainabeth Abella and Naberius all have ‘ab’ before they became Coronabeth and Ianthe#Which is super interesting itself. Coronabeth an Naberius retained that connection while Ianthe did not#Muir talks about how she was going for that naming theme then ultimately decoded to kinda drop it#But Palamades and Camilla get to share that syllable sound. Because they are on the same wavelength and they love each other#The Locked Tomb#Gideon the Ninth
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Stay hopeful, stay kind, dear Halsin.
#ozusart#bg3#baldur's gate 3#bg3 halsin#baldurs gate 3#halsin#oak father preserve me#hes so beautiful im actually so devastated#look at hinm#i love him so much#hes so beautiful#hes so babygirl#i hope he knows in every save i will always choose him that sounds so cringe but i am doomed to have him as my special interest
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the dialogue choices in this game should be more diabolical
#i love akechi but i sometimes i wish you could bully him like no matter which dialogue u pick it sounds like ur flirting back w him#“i'm going to be completely honest with you. i've always hated you” why can't u say smt unserious back#like “sorry i have a snatched waist and correct opinions on everything.” or like “ur loss lmao”#hate playing darts with this bitch bc i play on a steamdeck and i don't have a fucking gyroscope so like#it's trying to replicate how the joycons or pro controller would throw AND ITS SUCKS SO BAD#like i just see akechi get a hat trick every single fucking time with three bulls in a row and meanwhile im struggling to line the thing up#and then after u finish he's like “hmm i see. that's an interesting way to play it” WHAT THE FUCK THERES LITERALLY NO STRATEGY HERE SMARTAS#I JUST MISSED. IM NOT STRATEGIZING. THERES NOTHING “INTERESTING” ABOUT IT.#i hate going to penguin snipers so much i hope i can get this stupid game on switch so i can actually rank up akechi's baton pass#and not waste like 1000 yen every night bc i refuse to not let a party member be on rank 3#akechi fuck yourself why can't we play 501 like we do with everyone else. why do u have to make everything abt this stupid rivalry#im gonna kms i hate akeci and i hate darts#persona 5#persona 5 royal#p5#p5r#goro akechi#ren amamiya#akira kurusu#shuake#akeshu#lotus draws
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People sorting ao3 solely by stats and only clicking on fics with a certain amount of kudos or comments, you will not survive the winter, nor the summer, nor at all, *brings out knife,* run
#ao3#fanfiction#because if everyone thinks like that then so many fics that might be great get buried and fall into the void#someone has to read it with no hits or kudos#not to mention sometimes people just have wildly different tastes so you don't know unless you look at it yourself#i put a bunch of exclusion filters and then go by summary and tags and open all the ones that sound interesting to me#if they're bad well easy enough to move on#but lotta good ones hidden in there with not a comment in sight and i must change that#knife tw#?#tw knife mention
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"as seen on booktok" "booktok sensation" "popular on booktok" "booktok author"
#it's my dealbreaker#i'll be like oh this sounds interesting- no nvm#why does every bookstore have a separate booktok section now. we're in hell#books#leanne speaks
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