#the dopamine hit is too good

[yarodrags]

"I went to monsieur rossignol's night classes in 1760."

Monsieur Rossignol, pour quoi tu ne chantes pas?

A group of the two of them here

Very inspired by art noveau :D thought process behind the art here

Couldnt decide which version I liked better so here are both

There's no way aziraphales wings would be well groomed in heaven

[bigcats-birds-and-books]

Books of 2024: A SHINING by Jon Fosse.

Reading this next! It's a shortie (to the tune of seventy-four (74) pages), and the whole thing appears to be one (1) unbroken paragraph, but, hey: at least there's punctuation, I guess? It's about a guy who's driving directionlessly, gets out of the car at a forest, and wanders around on foot as it starts to snow, and when he inevitably gets lost, he meets some weird glowing....entity. The jacket copy calls this "strange, haunting, and dreamlike," which. yeah. I'm here for that. Will report back on how this goes!

[zaacoy]

SOMEONE ELSE ON TWT HAS MADE A TANG OUTFIT IN ANIMAL CROSSING TOO I MADE ONE LIKE A MONTH AGO AND HAVE BEEN WEARING IT SINCE THERE IS SOMEONE ELSE WHO IS THE SAME KIND OF INSANE AS ME YIPPPEEEEE YIPPPPPPEEEEE !!!! !!

[k-phoenix]

hello! i would love to hear the rant about PET scans :3

Holy shit so okay I'm in the train for the next 20 minutes, and I _know_ that's not enough time to get into all of it, but I could rant about this for hours, so. Maybe we cap this at 20 minutes. [20 minutes later] Okay so I wrote a huge wall of very boring text that barely started getting into it, so let me provide way less detail, actually:

It is massively expensive. A PET scanner costs a lot. And it's not a one time purchase, and then you can do scans, no, you wish. You also need some very expensive equipment to create radioactive tracers (which are what is used to do a PET scan) on site, because that stuff needs to be created fresh (under an hour) before every scan. To create the tracers is ALSO incredibly expensive. A single PET scan costs multiple thousands.

This also means that PET research makes use of as few participants as possible. A study with 15 participants is considered big. You simply cannot infer from 15 participants to the whole population. This also means that, statistically, it is highly likely that you don't find an effect even though it exists - meaning if your PET study looks for the effect of A on B, it is highly likely that it will find that A has no effect on B even though it does - simply because you didn't have enough participants (if this explanation doesn't make sense, let me know, and I can explain in detail)

This, together means, that an absolutely absurd amount of money is used for research that, by design, will not find results, because to find results, they would need more participants and even more money.

Because scientific publishing is a shitshow at the moment, research that doesn't find results very rarely gets published, especially not if you can't even be sure whether the result is right. So absurd amounts of money put into research that doesn't even get published.

And I haven't even talked about the results they did find and issues with them. Don't ask me to explain those. Don't tempt me to put hours into writing a multiple page essay that nobody will read.

So, in conclusion: PET is an absolutely amazing feat of engineering that is magnificent in detecting cancer and with it we could learn so. Much. More about the brain and how it works. But to do that, a lot of the basic organisation of how we do science would first need to change. Many labs would have to collaborate and be okay with making the collected data openly available, so appropriate sample sizes (=numbers of participants in a study) can even be achieved (Here's a paper on that). That probably won't happen, though.

Now, obligatory note: one of the professors who taught me about PET is a man who wrote an extremely controversial paper about exactly this stuff, despite also using PET in his research. If you like niche drama in science, look into this paper and all the articles that are responding to it.

[rainyjackalope]

I'm ngl I love posting new art here bc I love the attention so much. I'm like a dog that brought something into a room full of people and they're all praising me for my very good job and my tail is wagging so hard

[farawayfromdryland]

here's the thing. it used to be that you could take a bad book and make a pretty decent movie, or even a very good movie. or you take a good book and make, also, a good movie, just beware the decrying hoards of readers with expectations. now, nowadays...well

[prideandpen]

Seriously though nothing drives me crazy quite like making a perfect joke and the person I'm talking to simply liking it and not responding. Like where is his commitment to the bit! Who gave him the right to ignore me when I'm being hilarious in response to something he said!

[cuberry]

me when i’m running out of posts to make to farm interaction so i go for the low hanging fruit that is dunking on Blizzard and spew a bunch of bullshit that isn’t fact checked and has 0 source for most of it

The constant rolling disaster that is Overwatch's game development aside, what really perplexes me about how Blizzard is handling the broader franchise is their continual insistence that a canon narrative exists in spite of their equally continual refusal to tell anyone what it is.

Like, okay, the events of the games aren't canon. Fair enough: the games are multiplayer-only, and you can't account for player actions.

Oh, and the animated short films aren't canon either – they're properly understood as in-universe propaganda, not depictions of actual events. That's a little high concept for you guys, but fine.

But surely the comics are canon, right? Well, no; some of the comics (we're not telling you which ones) were canon at one point, but the writing team has decided to go in a different direction.

My dudes, what is left? The weird Source Filmmaker porn? Is that canon? Well, apparently it's at least as canon as anything else!

[savage-rhi]

Fuchsia 🫂

[suckfaggot]

it's official I'm addicted to alcohol. again.

[burningcomputerpersona]

person: *shows even the slightest hint of interest in music that I enjoy*

me: ah yes a new victim muhahahaha

[malachitezmeyka]

Save me happy brain chemicals

[mainfaggot]

I wish I didn't tell one of my close friends that I cut. she really didnt get it when I told her about it

[earanie]

I need a dopamine hit like yesterday but I don't know how to get it ughhhhh this is the worst

[iamthepulta]

look at my sexy new horse that's going to beat the pants off the Galloping Competition Community

I'm playing this game out of spite because when I was 14 it was heavily pay-to-play with in-game pass purchases (or I couldn't figure stuff out) so now I am playing this free game and I'm going to take over purebred Appaloosas because I feel like it.