#sspe treatment

[fidicusraredisease]

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Treatment For SSPE, Subacute Sclerosing Panencephalitis, Dowson Disease | Homeopathy Treatment Cure Relief | Rare Orphan Unique Disease | Dr. Bharadwaz

Speciality Clinic

Fidicus Rare Disease

highest success with homeopathy

Any Disease | Any Patient | Any Stage

About Video : "Exploring SSPE treatment options? Dive into the debate between conventional medicine's limitations and homeopathy's promises. Discover how conventional treatments for SSPE often fall short, leading to symptoms' persistence. Contrastingly, homeopathy's holistic approach and personalized remedies offer potential advantages, aiming for long-term relief. Uncover the pros and cons to make informed health decisions!"

[patientselftesting6732]

Genetic Factors and Single Subsegmental Pulmonary Embolism Risk

Pulmonary embolism (PE) is a potentially life-threatening condition characterized by the obstruction of pulmonary arteries by blood clots. While PE can affect various segments of the pulmonary vasculature, single subsegmental pulmonary embolism (SSPE) has garnered increasing attention due to its unique clinical features and management challenges. In this blog post, we delve into the genetic factors influencing SSPE risk and their implications for patient care and management.

Understanding Single Subsegmental Pulmonary Embolism (SSPE)

SSPE refers to the presence of a blood clot in a single subsegmental branch of the pulmonary artery, typically detected through imaging studies such as computed tomography pulmonary angiography (CTPA). Unlike larger pulmonary emboli that may cause significant hemodynamic compromise, SSPEs are often smaller and may exhibit varying clinical presentations, ranging from asymptomatic to mild respiratory symptoms.

Genetic Factors and SSPE Risk

Recent research has shed light on the role of genetic factors in predisposing individuals to venous thromboembolism (VTE), including pulmonary embolism. VTE encompasses deep vein thrombosis (DVT) and PE, with genetic predispositions contributing to thrombus formation and propagation. Several key genetic factors are implicated in SSPE risk:

Factor V Leiden Mutation

The Factor V Leiden mutation is one of the most well-known genetic risk factors for VTE, including PE. This mutation involves a change in the Factor V protein, leading to increased resistance to inactivation by protein C, a natural anticoagulant. Individuals carrying one or two copies of the Factor V Leiden mutation have a higher risk of developing thrombotic events, including SSPE.

Prothrombin Gene Mutation (G20210A)

The prothrombin gene mutation, specifically the G20210A variant, is another genetic factor associated with increased VTE risk. This mutation results in elevated levels of prothrombin, a key protein in the coagulation cascade. The combination of Factor V Leiden and prothrombin gene mutations further amplifies the thrombotic risk, including SSPE occurrence.

MTHFR Gene Polymorphisms

Methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms, particularly the C677T and A1298C variants, have been linked to altered homocysteine levels and thrombotic events. Elevated homocysteine levels are associated with endothelial dysfunction and increased clotting tendency, contributing to VTE risk, including SSPE.

Clinical Implications and Management Strategies

Understanding the genetic factors influencing SSPE risk is crucial for risk stratification, diagnosis, and management of affected individuals. Genetic testing may be considered in patients with unprovoked or recurrent VTE events, especially in younger individuals or those with a family history of thrombotic disorders. Identifying specific genetic mutations allows for personalized risk assessment and tailored anticoagulation strategies.

Anticoagulation Therapy

Anticoagulation remains the cornerstone of SSPE management, aimed at preventing clot propagation and recurrent thrombotic events. The choice of anticoagulant agents, such as direct oral anticoagulants (DOACs) or vitamin K antagonists (VKAs), depends on individual patient factors, including genetic profile, comorbidities, and bleeding risk.

Lifestyle Modifications and Follow-Up

In addition to pharmacological therapy, lifestyle modifications such as maintaining a healthy weight, regular physical activity, and smoking cessation are essential in reducing VTE recurrence risk. Regular follow-up evaluations, including imaging studies and laboratory monitoring, help assess treatment efficacy and identify potential complications.

Genetic Insights for SSPE Management with PatientSelfTesting

In conclusion, genetic factors play a significant role in single subsegmental pulmonary embolism risk, influencing thrombotic propensity and treatment outcomes. Incorporating genetic testing into clinical practice allows for personalized risk assessment and optimized management strategies for SSPE patients.

At PatientSelfTesting, we recognize the importance of genetic insights in pulmonary embolism management, offering advanced genetic testing solutions to healthcare providers and patients. Partner with PatientSelfTesting to leverage genetic knowledge and improve outcomes in SSPE and venous thromboembolism care.

[alicesara611]

Inosine Pranobex Market Forecast: 5-Year Outlook By 2023 to 2028

The global inosine pranobex market is expected to reach US$ 234.5 million by 2028, growing at a CAGR of 2.2%. The growth of the market is attributed to the increasing prevalence of respiratory diseases, such as chronic obstructive pulmonary disease (COPD), asthma, and influenza. Inosine pranobex is a drug that has been shown to be effective in the treatment of these diseases.

Inosine pranobex (IP) is an antiviral and immunomodulatory drug used to treat a variety of viral infections, including subacute sclerosing panencephalitis (SSPE), herpes simplex virus (HSV), human immunodeficiency virus (HIV), human papillomavirus (HPV), influenza, and acute respiratory infections. IP is available in tablet and syrup form.

Discover Our Expert Analysis with Our Sample Report! https://absolutemarketresearch.com/Global-Inosine-Pranobex-Market/2037/request-sample

Inosine Pranobex is an antiviral medication used to treat respiratory infections, including the common cold and the flu. It is also used to prevent respiratory infections in people who are at high risk. Inosine Pranobex is not a cure for the common cold or the flu, but it can help to shorten the duration of the illness and reduce the severity of symptoms.

Key Takeaways:

The global inosine pranobex market is expected to reach US$ 234.5 million by 2028, growing at a CAGR of 2.2%.

The market is driven by the increasing prevalence of viral infections and the growing demand for immunomodulators.

Asia Pacific is expected to be the fastest-growing regional market, due to the large and growing population and the rising prevalence of viral infections.

The tablets segment is expected to be the largest segment of the market, due to their ease of use and convenience.

Regional Outlook:

North America: The North American inosine pranobex market is expected to grow at a CAGR of 1.5% from 2023 to 2028.

Europe: The European inosine pranobex market is expected to grow at a CAGR of 2.0% from 2023 to 2028.

Asia Pacific: The Asia Pacific inosine pranobex market is expected to grow at a CAGR of 3.0% from 2023 to 2028.

South and Central America: The South and Central American inosine pranobex market is expected to grow at a CAGR of 2.5% from 2023 to 2028.

Key Players:

Newport Pharmaceuticals

Gedeon Richter

Mochida

Sanofi-Aventis

Yung Shin

Sigma-Tau

Polfarmex

Sanfer

Meprofarm

Novell Pharmaceutical

Aflofarm

Market Segmentation:

The inosine pranobex market is segmented by type, application, and geography.

Type:

Tablets

Syrup

Application:

Immunomodulation

Antiviral applications

Others

Geography:

North America

Europe

Asia Pacific

South and Central America

[itsdoctorhouse]

Paternity

CC: Diplopia, night terrors ongoing 3 weeks, and a myoclonic jerk

Dx: Subacute sclerosing panencephalitis (SSPE)

Diplopia:

aka double vision: the perception of two images instead of a single object

Common causes usually stem from issues with the eyes, muscles and nerves controlling the eyes, and the brain.

Night terrors:

As mentioned in the episode, there are two leading causes for onset teenage night terrors: PTSD and sexual abuse.

Personally I think there isn’t much reason for the patient to have experienced night terrors beyond the initial stages of SSPE causing changes in emotional behavior and personality.

Myoclonic jerk:

Brief, involuntary twitching of some muscles; generally in healthy persons it can be seen right before falling asleep (aka a hypnic jerk).

The patient presents it even though he’s not asleep or tired.

Multiple sclerosis (MS):

In the episode:

After testing some CSF, because of a buildup and blockage, they find high levels of IgG and assume multiple sclerosis, but find no evidence of lesions. A good assumption because over 80% of patients with MS show oligoclonal bands with high IgG.

Since the patients symptoms have only begun 3 weeks previously they determine it’s rapidly progressive MS.

They can’t definitively diagnose MS, because there are no specific tests for it. Generally doctors have to rule out every other possibility before they can confirm. What’s mentioned in the episode is waiting 6 months to confirm, most likely to see progression of symptoms as well as ruling out differentials.

More on Marburg MS s7e08 “Small Sacrifices”

MS is a chronic central nervous system disease in which the myelin sheath and nerve axons in the brain are destroyed. It’s referred to as a demyelinating disease. The damage disrupts the ability to transmit signals which can result in a slew of signs and symptoms.

The three main characteristics are the formation of lesions/plaques in the CNS, inflammation and the destruction of myelin sheaths of neurons

Other specific symptoms usually include diplopia, blindness in one eye, muscle weakness, and trouble with sensation or coordination.

Some pathognomonic signs include:

Internuclear ophthalmoplegia (INO): an impairment in the lateral conjugate gaze, meaning that when both eyes are looking toward one side the affected eye cannot properly adduct (move toward the center). Caused bye a lesion in the medial longitudinal fasciculus (part in the brainstem).

To put it simply, if the right eye is affected, the patient should be able to look to the right, and cross their eyes, but upon looking to the left, the right eye won’t be able to move to the midline.

Positive Romberg’s sign: when the patient sways or falls with their eyes closed. It demonstrates a loss of postural control and proprioception (perception and awareness of one’s body) in the absence of visual input.

Positive Lhermitte’s sign: paresthesia/an electrical shock that passes down the back of the neck and spine, usually brought upon by bending the head forwards towards the chest.

Progression usually occurs as episodes of worsening lasting days to months, followed by improvement (relapsing episodes).

Subacute sclerosing panencephalitis (SSPE):

Early in the episode Cameron admits to not having taken a full history or family history which really would have solved the case a hell of a lot sooner, given his birth mother was the cause of the patients issues.

tbf, it was the whole point of the episode to focus on determining paternity, which, given all the daddy issues on the show is a good setup.

Then again, the patient is a 16 year old lacrosse player, and he figured out he was adopted at a much younger age, 10 if I remember right, just from having a cleft chin. Talk about selective blindness on the team.

aka Dawson disease

SSPE is a super rare complication from measles wherein there is chronic progressive brain inflammation caused by the mutated virus.

Patients generally have history of a primary measles infection in infancy (where the birth mother was not vaccinated and thus could not pass along the proper antibodies to protect the infant for up to 6 months), followed by an asymptomatic period that can last up to 27 years. Afterwards neurological deterioration ensues with behavioral changes, myoclonic seizures, visual disturbances, ataxia, and ultimately death.

Anti-measles IgG appears to increase as the disease progresses

There is no definitive cure, but if it is diagnosed in the first stage of the disease oral isoprinosine and intraventricular interferon alfa could help, it varies patient to patient. And the only accepted treatment are purely supportive: anticonvulsants.

Should not be confused with acute disseminated encephalomyelitis (ADEM), which can also be caused by the measles virus.

Another demyelinating disease, it is a rare autoimmune disease with acute inflammation of the brain and spinal cord.

Often triggered by a viral infection or specific non-routine vaccinations.

Very closely resembles symptoms of MS except for usually occurring in children and marked with rapid fever.

[morganmcjiggleson]

When you’ve been infected by the measles virus it stays in your brain, and can re-emerge years later in the form of something called subacute sclerosing panencephalitis or SSPE. No one knows why or how it happens, but it can reawaken and causes an immune response that leads to seizures, coma and death. There’s no treatment and no one has been known to survive it.

VACCINATE YA KIDS FFS

[bookpiofficial]

Movement Disorder Early in the Presentation of Two Children with Subacute Sclerosing Pan-Encephalitis | Chapter 09 | Innovations in Medicine and Medical Research Vol. 1

Subacute sclerosing panencephalitis (SSPE) is a progressive degenerative disease caused by measles infection with overall poor prognosis in spite multiple modalities of treatment. The course of the disease is characterized by progressive neurological decline in the form of behavioral and personality changes followed by a stage of characteristic periodic myoclonic spasms followed by a stage of quadriplegia movement disorder, vegetative state and frequently early death. Here we report two cases with atypical presentation of early rather than late movement disorder during illness and the unusual association of central precocious puberty preceding the course of illness in one of the cases.

Author(s) Details

Hanin Al-Gethami Neuro-Science Center, King Fahd Medical City, Riyadh, Saudi Arabia

Mohammad Talal Alrifai Pediatric Neurology Division, Department of Pediatrics, King Abdullah Specialist Children Hospital, King Abdulaziz Medical City, Riyadh, Saudi Arabia.

Ahmed Al-Rumayyan Pediatric Neurology Division, Department of Pediatrics, King Abdullah Specialist Children Hospital, King Abdulaziz Medical City, Riyadh, Saudi Arabia.

Waleed Al-Tuwaijri Pediatric Neurology Division, Department of Pediatrics, King Abdullah Specialist Children Hospital, King Abdulaziz Medical City, Riyadh, Saudi Arabia.

Duaa Ba-Armah Pediatric Neurology Division, Department of Pediatrics, King Abdullah Specialist Children Hospital, King Abdulaziz Medical City, Riyadh, Saudi Arabia.

View Volume: http://bp.bookpi.org/index.php/bpi/catalog/book/139

[doyouthatknow]

Subacute sclerosing panencephalitis, diagnosis and treatment methods

Subacute sclerosing panencephalitis, diagnosis and treatment methods

What is subacute sclerosing panencephalitis? What are the symptoms of this disease? What Is Subacute Sclerosing Panencephalitis?

Subacute sclerosing panencephalitis SSPE is briefly referred to as. The central nervous system caused by the measles virus, is a viral infection progressive. Is a brain disorder that is caused by the measles virus. This condition is a fatal virus.

After experiencing…

[n8n3n3-blog]

Subacute sclerosing panencephalitis (SSPE)/ Dawson Disease Neurological Case Review Diagnosis Treatment No Cure but managed with Antiviral therapy(ribavirin,amantadine), Interferon(oral isoprinosine),anticonvulsants, palliative care(nursing and nasogastric feeding). Know More

[fidicusraredisease]

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What is SSPE? or Subacute Sclerosing Panencephalitis or Dowson Disease - Homeopathy | Treatment Cure Relief | Rare Orphan Unique Disease | Dr. Bharadwaz

Speciality Clinic

Fidicus Rare Disease

highest success with homeopathy

Any Disease | Any Patient | Any Stage

About Video : In this video, we explore Subacute Sclerosing Panencephalitis (SSPE), a rare but fatal brain disorder. Learn how SSPE develops as a complication of the measles virus, typically appearing years after the initial infection. We discuss its symptoms, which include behavioral changes, motor dysfunction, and seizures, and highlight the importance of early diagnosis and vaccination in prevention. Join us to understand the medical complexities and the critical need for awareness about SSPE.

[fidicusraredisease]

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Precautions, neglect Complications SSPE, Subacute Sclerosing Panencephalitis | Treatment Cure Relief | Rare Orphan Unique Disease | Dr. Bharadwaz

Speciality Clinic

Fidicus Rare Disease

highest success with homeopathy

Any Disease | Any Patient | Any Stage

About Video : Diving into SSPE, let's navigate through essential precautions and prognosis means what happens when you neglect this disease. Explore crucial steps to safeguard against SSPE, understanding the disease's trajectory and potential outcomes. Gain insights into preventive measures, prognosis factors, and proactive approaches for managing this challenging condition. Empower yourself with knowledge for a better understanding of SSPE's journey.

[fidicusraredisease]

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3rd and 4th stage symptoms of SSPE or Subacute Sclerosing Panencephalitis . | Homeopathy | Treatment Cure Rare Orphan Unique Disease

Fidicus Homeopathy offers a safe, effective, and affordable treatment for complications of SSPE (Subacute Sclerosing Panencephalitis). Our personalized remedies work to relieve symptoms, prevent progression, and aim to cure the root cause, providing hope and improved quality of life for patients.

Dr. Bharadwaz | Rare Orphan unique Disease | Health & Fitness | Homeopathy, Medicine & Surgery | Clinical Research

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[fidicusraredisease]

Call : +917997101303 | Whatsapp : https://wa.me/917997101505 | Website : https://fidicus.com

Second stage symptoms of SSPE or Subacute Sclerosing Panencephalitis . | Homeopathy | Treatment Cure Rare Orphan Unique Disease

Fidicus Homeopathy offers a safe, effective, and affordable treatment for complications of SSPE (Subacute Sclerosing Panencephalitis). Our personalized remedies work to relieve symptoms, prevent progression, and aim to cure the root cause, providing hope and improved quality of life for patients.

Dr. Bharadwaz | Rare Orphan unique Disease | Health & Fitness | Homeopathy, Medicine & Surgery | Clinical Research

Dawsonsencephalitis #SSPE #Subacutesclerosingpanencephalitis #Measles

DrBharadwaz #Helseform #Fidicus #Clingenious

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Speciality Clinic Fidicus Rare Disease highest success with homeopathy Any Disease | Any Patient | Any Stage

[fidicusraredisease]

Call : +917997101303 | Whatsapp : https://wa.me/917997101505 | Website : https://fidicus.com

First stage symptoms of SSPE or Subacute Sclerosing Panencephalitis . | Homeopathy | Treatment Cure Rare Orphan Unique Disease

Fidicus Homeopathy offers a safe, effective, and affordable treatment for complications of SSPE (Subacute Sclerosing Panencephalitis). Our personalized remedies work to relieve symptoms, prevent progression, and aim to cure the root cause, providing hope and improved quality of life for patients.

Dr. Bharadwaz | Rare Orphan unique Disease | Health & Fitness | Homeopathy, Medicine & Surgery | Clinical Research

Dawsonsencephalitis #SSPE #Subacutesclerosingpanencephalitis #Measles

DrBharadwaz #Helseform #Fidicus #Clingenious

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[fidicusraredisease]

Call : +917997101303 | Whatsapp : https://wa.me/917997101505 | Website : https://fidicus.com

Signs and Symptoms of SSPE or Subacute Sclerosing Panencephalitis . | Homeopathy | Treatment Cure Rare Orphan Unique Disease

Fidicus Homeopathy offers a safe, effective, and affordable treatment for complications of SSPE (Subacute Sclerosing Panencephalitis). Our personalized remedies work to relieve symptoms, prevent progression, and aim to cure the root cause, providing hope and improved quality of life for patients.

Dr. Bharadwaz | Rare Orphan unique Disease | Health & Fitness | Homeopathy, Medicine & Surgery | Clinical Research

Dawsonsencephalitis #SSPE #Subacutesclerosingpanencephalitis #Measles

DrBharadwaz #Helseform #Fidicus #Clingenious

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[fidicusraredisease]

Call : +917997101303 | Whatsapp : https://wa.me/917997101505 | Website : https://fidicus.com

Complications of SSPE or Subacute Sclerosing Panencephalitis . | Homeopathy | Treatment Cure Rare Orphan Unique Disease

Fidicus Homeopathy offers a safe, effective, and affordable treatment for complications of SSPE (Subacute Sclerosing Panencephalitis). Our personalized remedies work to relieve symptoms, prevent progression, and aim to cure the root cause, providing hope and improved quality of life for patients.

Dr. Bharadwaz | Rare Orphan unique Disease | Health & Fitness | Homeopathy, Medicine & Surgery | Clinical Research

Dawsonsencephalitis #SSPE #Subacutesclerosingpanencephalitis #Measles

DrBharadwaz #Helseform #Fidicus #Clingenious

ClingeniousHealth #HelseformFitness #FidicusHomeopathy #ClingeniousResearch

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[fidicusraredisease]

Call : +917997101303 | Whatsapp : https://wa.me/917997101505 | Website : https://fidicus.com

Signs and Symptoms of SSPE or Subacute Sclerosing Panencephalitis . | Homeopathy | Treatment Cure Rare Orphan Unique Disease

Fidicus Homeopathy offers a safe, effective, and affordable treatment for complications of SSPE (Subacute Sclerosing Panencephalitis). Our personalized remedies work to relieve symptoms, prevent progression, and aim to cure the root cause, providing hope and improved quality of life for patients.

Dr. Bharadwaz | Rare Orphan unique Disease | Health & Fitness | Homeopathy, Medicine & Surgery | Clinical Research

#Dawsonsencephalitis #SSPE #Subacutesclerosingpanencephalitis #Measles

#DrBharadwaz #Helseform #Fidicus #Clingenious

#ClingeniousHealth #HelseformFitness #FidicusHomeopathy #ClingeniousResearch

#FidicusRareDisease #RareDiseaase #OrphanDisease #UniqueDisease

#Treatment #Cure #Prevent #Relieve

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Speciality Clinic Fidicus Rare Disease highest success with homeopathy Any Disease | Any Patient | Any Stage