#siteman cancer center

[partisan-by-default]

A small clinical trial shows promising results for patients with triple-negative breast cancer who received an investigational vaccine designed to prevent recurrence of tumors. Conducted at Washington University School of Medicine in St. Louis with a therapy designed by WashU Medicine researchers, the trial is the first to report results for this type of vaccine — known as a neoantigen DNA vaccine — for breast cancer patients.

The study, which found the vaccine to be well-tolerated and to stimulate the immune system, is available Nov. 14 in the journal Genome Medicine.

The phase I clinical trial — conducted at Siteman Cancer Center, based at Barnes-Jewish Hospital and WashU Medicine — involved 18 patients diagnosed with triple-negative breast cancer that was not metastatic, meaning it had not spread to other organs. Each patient received the standard of care and three doses of a personalized vaccine tailored to home in on key mutations in their specific tumor and train immune cells to recognize and attack any cells bearing these mutations.

Following treatment, 14 of 18 patients showed immune responses to the vaccine and, after three years, 16 patients remained cancer-free. While the early-stage trial was designed to evaluate safety of the vaccine and did not include a control group to determine efficacy, the researchers analyzed historical data from patients with triple-negative breast cancer treated with the standard of care only. In that group, on average, about half of patients remained cancer-free at three years post-treatment.

Vaccines are good science. Here is just another example of how well they work..

[justjibberjabber]

they tell me i’m good as new...

I started writing this a few weeks ago, but as I say further on in the post – life moves forward sometimes at a crushing speed, and we don’t always have the luxury of time and space to process, comprehend, and do all the things we want to do. So anyway, it’s coming to you a couple weeks late.

Today I realized that it still hurts to talk about it.

It somehow came up in conversation at work, and although I spoke about it briefly and generally, it prepared me to talk more deeply about it on the phone the next day to the representative from Imerman’s Angels – a cancer support group that will match me, a cancer survivor, with someone who is newly diagnosed with the same type of cancer that I went through.

Of course, once our phone call was over, the day rushed on – things to do, places to go, chores to be done. It wasn’t until the quiet of night, when my body lay still and the air lay silent, that my thoughts began to churn.

I thought about all the details. All the things and events, big and small, in Cambodia. It was like watching a movie – meeting my host family for the first time in the temple, with the monks chanting in their saffron robes and the thick air pressing in on us. Fussing with my mosquito net every night while getting up to go to the bathroom, trying to quietly sneak my window open just to catch a bit of the cooler night air. Being led around my host grandpa’s living room as he pointed at pictures of his wife and daughter, and all I could say was “seh-ahd-nah” – very beautiful. Muddy puddles in the market, my language teacher’s pink lipstick, jackfruit in the backyard. Squeezing my lips together during cistern baths so as not to drink the water, chickens darting through the house, skin sticky all the time with sweat and bug spray and sunscreen. The constant, crushing pain, angst, of having left behind my loved ones in America, as if my heart were a wet dish rag being rung out repeatedly, until there was nothing left. Making the mistake of getting a SIM card for my phone, making home both more and less accessible. Calling my parents to wake them up at 2 am, sobbing hysterically that I couldn’t be apart like this from the ones I loved and that I would be home soon. Waiting all weekend in a hotel in Phnom Penh where the showers were cold, the bed had ants, and time seemed to completely halt its relentless march forward. I walked to Central Market, I did yoga in my room, I ate a Domino’s pizza. And still, my reunion felt so far away. My heart lay feeble in my chest, but hope at last it did have.

A six-hour flight to Seoul. A sixteen-hour flight to Detroit. A quick hop in a rickety plane to St. Louis.

Home. I was finally home. My plane was landing, and St. Louis had never looked so beautiful. My mom was there with a peanut butter and jelly sandwich. My old standard. I went to the bathroom, and when I came back I found my Mom sitting in an airport chair gazing at the floor. She looked so small. Just three weeks before we had been in the same place saying goodbye – I had clutched my sister-in-law’s hand in the parking lot, wet my dad’s gray pocket t-shirt with my tears, hugged them all one by one, and then hugged them all again. I had been so distraught going through security that even the TSA agents were kind to me. As my Mom sat there with her hands in her lap, clearly overwhelmed, I hated myself for having put my family through this. But overjoyed we were to be together again. Things were back to the way they were supposed to be.

The following weeks were so immensely happy, such tranquility and peace in my heart, euphoric. I was home with my loved ones where I knew I belonged. I felt a calm that I had never felt. I watched sunrises and sunsets in the place where I grew up. I took walks down the road and let the clouds roll over me. The front porch invited me in, and I sat and looked outward onto memories of childhood spent in the front yard. Every breath was deep and meaningful, sweet inside my lungs. A dark weight had been lifted from my chest, and my heart soared. I cried unabashedly at the balloon fest; I looked over at my Mom and told her through my tears how happy I was to be home. I felt so secure, so safe; I had made the right decision. I was on cloud nine; I was high. And yet every one of these is such a poor description of the profound peace and happiness I felt.

“All three spots actually came back positive for something called papillary thyroid carcinoma.”

Everything shattered. I came hurtling down through miles of clouds and sunshine and happy memories and soft blankets of security and crashed in a doctor’s office where suddenly the walls were too white, the people too stiff, the lights too blinding, the floor beneath me hard as stone.

In two seconds, my emotional gears, which had been cranking out some incredibly transcendent feelings for a few weeks, lurched and screeched and came to a grinding halt to turn production in the opposite direction.

I felt small and fragile, like a child. I sat on a bench outside the hospital with my Mom, the September heat around us, and curled under her arm to cry. The days that came brought fear, sleeplessness, anxiety, depression, despair. I felt sick the night before surgery, then undisguised terror being wheeled back to the OR.

I survived.

I spent the next four days in the hospital, my parents sleeping in chairs next to me. I woke up at odd times through the night in pain. My Mom sat next to me at 2 am, as if things were normal, as I colored postcards for the friends I had made in Cambodia and listened to my John Mayer Pandora station in an attempt to get Eve 6’s “Heart in a Blender” out of my head. It must have been on the OR’s playlist during my induction or extubation.

It sounds weird, but sometimes when life gets really crazy, there’s a part of me that wants to go back to those four days in the hospital, JP drains in my neck and all. My time there, those days and nights that melted unrecognizably into each other, was oddly comforting to me – my parents right there; Clay visiting me every morning and every night around his work schedule, taking me for shaky walks up and down the hallway; my Mom adjusting my pillows or helping me to the bathroom. Psychologists might call it regression.

I went back to work five weeks later, sooner than I was ready. And just like that, life moved on, leaving me hustling to catch up emotionally. A couple courses of high dose radiation, a tiny blue pill every morning forty minutes before breakfast, and they tell me I’m good as new.

I haven’t thought this deeply in a long time about how the scar on my neck all started, how it all began. There are so many details, so many emotions, so many moments both weak and strong, that are impossible to portray in a blog post. Impossible to convey at all, really. I don’t know why I want so badly to be understood.

But I learned today that it still hurts, and it still brings unrestrained tears if I give it too much of my time.

It probably will always hurt. At least a little bit.

[bpod-bpod]

No Two Alike

For more than a century, scientists have been trying to understand what drives cancer. Today, we know that it’s a disease underpinned by genetic changes (mutations) that cause cells to grow out of control, eventually forming a tumour. Highly sensitive DNA sequencing technology means that we can now look in depth at the mutations in ever smaller pieces from individual tumours – and the more we discover, the more complicated it gets. These images are visual representations of detailed DNA sequencing of small pieces of individual bowel tumours, with groups of cells (clones) carrying particular patterns of mutations highlighted in different colours. The results show that no two cancers are the same, and that there’s huge variation in how these clones grow and the mutations within them. This means that each patient needs a personalised approach to treatment, rather than one-size-fits-all therapy, in order to get the best outcome.

Written by Kat Arney

Image adapted from work by Ha X. Dang and colleagues

The Alvin J. Siteman Comprehensive Cancer Center, Washington University in St. Louis, St. Louis, MO, USA

Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)

Published in Science Advances, June 2020

You can also follow BPoD on Instagram, Twitter and Facebook

[bs8925]

First round of #taxol #chemosucks #chemo round 5 #cancerstrong #cancersurvivor #cancer2020 #cancerwarrior #tpnbreastcancer #triplenegativebreastcancer #breadtcancerawareness #youngcancer #cancerunder40 #triplenegative (at Siteman Cancer Center) https://www.instagram.com/p/CIY9m9qjJTv/?igshid=jatzxtdi8ynw

[investmart007]

Washington University News: Gift allows Siteman Cancer Center to establish resiliency program for nurses

New Post has been published on https://is.gd/o659or

Washington University News: Gift allows Siteman Cancer Center to establish resiliency program for nurses

ST LOUIS, MO – A $500,000 donation to Washington University School of Medicine in St. Louis will be used to provide resiliency training for nurses at Siteman Cancer Center at Barnes-Jewish Hospital and the School of Medicine.  The program will be aimed at improving care for them and, ultimately, their patients.

The gift establishes the Josh Gottheil Memorial Endowment for the Promotion of Resiliency, which will support symposia and other programs to teach nurses scientifically proven methods for maintaining good mental and emotional health so they may continue caring for patients with empathy and understanding.

_____

SOURCE: news provided by SOURCE.WUSTL.EDU on July 11, 2018

[emilysuessbtsm-blog]

Just the Facts

Repost from Facebook in case you don’t get updates there: 1. We are home from another 6-week checkup at Siteman Cancer Center in St. Louis. 2. My platelets are up from 51 last week to 64 this week. So they’re finally climbing again instead of tanking. 3. My platelet count has to reach 100 before I can take next my chemo round, but the oncologist sent me home with the pills and told me they’ll…

[alwaysfirst]

According to a study, sugar metabolism is common in cancer

Aug 20, 2022 19:12 IST Washington , August 20 (AF): For more than a century, cancer cell metabolism has been regarded as a puzzle. Recent research from Washington University in St. Louis suggests that it may not be an anomaly after all. On August 15, the study was published in Molecular Cell. Glucose, a common sugar present in the diet, is one of the most important nutrients in the body. It is consumed at an alarming rate by cancer cells. At first glance, this seems fair because cancer cells must synthesise a variety of substances. Because cancer spreads rapidly, each cell must replicate every component within it. But there's a catch. Cancer cells do not make good use of glucose. Instead of collecting every ounce of energy possible from glucose, they squander the vast majority of it. Gary Patti, the Michael and Tana Powell Professor of Chemistry in Arts & Sciences, as well as genetics and medicine at the School of Medicine, noted that for cells to receive the greatest energy from glucose, its transformation products must be moved into mitochondria. Patti, who works at the Siteman Cancer Center at Barnes-Jewish Hospital and the School of Medicine, is the present study's senior author. The metabolism is anticipated to follow certain biochemical rules. Patti described her fascination with the many causes malignancies may be allowed to ruin people. However, the data presented here reveal that cancer cells do follow established guidelines. Overflowing The smallest compartments within cells known as mitochondria are sometimes referred to as the cell's power plants or powerhouses. They maintain stringent restrictions over what comes and goes. To set the stage, in the 1920s, a prominent scientist named Otto Warburg made the first discovery of tumour wastefulness. He argued that cancer cells had damaged mitochondria as a solution to the mystery of why more energy isn't produced from glucose. We now know that this is false. According to Patti, most tumours feature functioning and active mitochondria. However, this does not explain why cancer cells metabolise so little of the glucose they consume in mitochondria, which is a vexing and long-standing mystery. According to Patti, what has confused experts is the thought that cancer cells chose not to metabolise glucose in their mitochondria. The theory has repeatedly circulated that cancer cells want to use glucose inefficiently, either because of Warburg's original thought or because it occurs so frequently. There are several reasons why cancer cells could choose to squander their glucose. Patti and his colleagues argue that these arguments may not be necessary. Finally, scientists may be mistaken about how unusual cancer metabolism is. Cancer cells aggressively metabolise glucose in their mitochondria because they truly want to. According to Patti, nearly all of the glucose that cancer cells are unable to consume ends up in mitochondria. However, as glucose consumption increases, the pace at which glucose-derived molecules are delivered into mitochondria cannot keep up. In other words, cancer cells only squander glucose because mitochondrial transport is excessively slow. Consider a bathtub faucet that is leaking at a pace that exceeds the capacity of the drain. Eventually, the water rushes onto the floor. This metabolic paradigm is not completely novel. According to Patti, most cells prefer oxidising glucose in their mitochondria to excreting it as waste. "Our data suggest that cancer cells are prevalent." They appear to follow biochemical processes that are comparable to those of other cells. Saturated The Patti team's accomplishment was made possible by the powerful method known as metabolomics. According to Patti, "great developments in the field of metabolomics and mass spectrometry have occurred in the previous ten years." "We are already at a point where we can even test substances in single cells." Metabolomics and stable isotope tracers were used in this study. Researchers were able to tag various components of glucose and monitor them inside cells while also measuring the pace at which chemicals entered mitochondria or were expelled from cells. When scientists realised that cancer cells were outpacing or getting saturated with the typical fuel transport routes, they made this finding. (AF) Read the full article

[appro880]

Innovations in Medicine...

[glassstreetclinic]

Major Medical Centers

Major Medical Center Essendon are medical facilities with extensive clinical expertise. These hospitals represent the most comprehensive and advanced sites of health care in the United States. While many are similar in size and scope, they vary in the type of services they offer, ownership, and structure. In some cases, a Medical Center is both a hospital and a research and academic institution. Listed below are some of the most prominent major medical centers. Read on for more information.

A Medical Center is a facility where physicians and other healthcare professionals are trained. The facilities at a Medical Center are similar to those of a clinic, offering basic primary care. The difference is in the type of medical services they offer. For example, a hospital provides specialty care that is not available at a medical center. A clinic is more focused on primary care and offers less advanced treatments. A Medical Centre will be more focused on treatment and prevention, whereas a Medical Center will provide diagnostic services.

A Medical Center offers specialized care and is often a complex of several hospital and clinics. It can also be an incubator for medical research and education. Some Medical Centers include a medical school in the same complex. However, other institutions are closely associated and may not be referred to as a Medical Center. There are many types of Medical Centers, and the best one for you is the one that provides the most advanced care. And a medical center can offer both emergency care and specialized care.

A Medical Center can be anything from a hospital or clinic to a medical center. The majority of medical centers are not hospitals. Instead, they include specialized clinics and hospitals. Some centers are research institutions or incubators. The Texas Medical Corporation is a prime example. It is a campus that covers seventeen city blocks. It includes the Barnes-Jewish Hospital and the Alvin J. Siteman Cancer Center. In addition, it includes the Washington University School of Medicine and St. Louis College of Pharmacy.

Major medical centers provide many different kinds of medical care. In fact, a Medical Center may have multiple hospitals and clinics specializing in one or more areas of medicine. It is also a major incubator for medical innovation and educational activities. TMC innovation will bring together the most innovative innovators in the field of medicine with the most cutting-edge technologies and therapies to advance medical research. These innovative efforts will improve the quality of life for all patients.

A Medical Center is a hospital or clinic that offers a range of medical services. It may contain multiple hospitals and clinics in one complex. A Medical Center also has a medical school. A Medical School is a place where doctors and researchers work together. A Medical School is a key part of a Medical Community. Its primary function is to provide access to health care. Its name is often the same as a Hospital.

A Medical Center is similar to a hospital in some ways. A Medical Center can provide various medical services. Some major medical centers include specialized clinics and hospitals. Some centers are incubators for medical innovation and education. For example, a TMC Innovations Institute helps companies take their products from the bench to the bed. The TMC innovation Institute is the only one of its kind in the world. This is an important step for a growing healthcare system to continue to be successful.

In addition to hospitals, Medical Centers can offer many specialized services. The most common type of Medical Centers are hospitals, clinics, and universities. They are also the sites of research, education, and medical care. While the latter provides more comprehensive care, they do not provide all of these services. The TMC Innovation Institute is the ideal place to create new therapies and innovations. This is where medical centers come into play. They can be the hub for the medical industry.

The TMC Innovation Institutes are a key component of the TMC. These innovative and technologically advanced healthcare institutions will work together to develop new technologies and develop new medical procedures. Some of the institutes at TMC Innovations include biotech, genetics, and psychiatrics. These programs are designed to help the TMC become a leading global player in life science. The TMC is one of the most comprehensive and successful health care systems in the world.

[essaynook]

So many diseases can be prevented if you assess your risk factors and consult yo

So many diseases can be prevented if you assess your risk factors and consult yo

So many diseases can be prevented if you assess your risk factors and consult your medical professional early on. Visit the Washington University School of Medicine’s Siteman Cancer Center website (Direct Link: https://siteman.wustl.edu/prevention/ydr/?ScreenControl=YDRGeneral&ScreenName=YDRHome.htm) to assess your risk of the following diseases: Cancer Diabetes Heart…

[alwaysfirst]

Researchers find blood test shows neurotoxic complications of CAR-T cell therapy

Sep 02, 2022 00:07 IST Washington , September 2 (AF): The treatment of various tumours has been transformed by cell-based immunotherapy, often known as CAR-T cell therapy. In order to target and combat specific forms of leukaemia and lymphoma, the treatment employs genetically engineered T cells. While it has the potential to cure cancer in certain individuals who would otherwise pass away from the disease, it also carries the danger of a number of adverse effects, some of which can be fatal and disrupt brain function. The findings of the study were published in the journal JAMA Oncology. A new study from Washington University School of Medicine in St. Louis suggests a simple blood test -- administered before CAR-T cell treatment is initiated -- may identify which patients are predisposed to developing neurotoxic side effects in the days and weeks after CAR-T cell therapy. Analyzing blood samples from patients before, during and after CAR-T cell therapy, the researchers found that levels of a protein called neurofilament light chain (NfL) are higher in patients who go on to develop neurotoxic complications. High levels of the protein are present even before therapy begins, and those levels remain elevated throughout treatment and up to a month afterward. The research could help doctors anticipate these life-threatening side effects and allow them to begin giving treatments that can reduce the neurotoxic effects early during a patient's treatment. It also opens the door to developing ways to prevent the side effects or reduce their risk before CAR-T cell therapy begins. "Our study suggests that some patients receiving CAR-T cell therapy have previously undetected damage to neurons present at baseline, before we even begin preparing them for this treatment," said lead author Omar H. Butt, MD, PhD, an instructor in medicine who treats patients at Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine. "We don't know the origin of this damage, but it appears to predispose them to developing neurotoxic complications. If we understand who is at risk of these complications, we can take early steps to prevent it or reduce the severity." A general marker of damage to neurons, the NfL protein has been used to measure or monitor the severity of several neurologic diseases, including Alzheimer's disease and multiple sclerosis. "Measures of NfL in the blood are being used as a way to evaluate the effectiveness of potential new therapies for multiple sclerosis," said co-senior author Beau M. Ances, MD, PhD, the Daniel J. Brennan Professor of Neurology. "We plan to continue our studies to find the origin of neuronal damage in these cancer patients. This is a unique collaboration that was possible at Washington University because we have some of the top experts in CAR-T cell therapy and leading expertise in neurodegenerative diseases. It presents a great opportunity to bridge gaps and bring these fields together to try to solve a vexing problem and help patients." The study was relatively small, involving 30 patients treated at Siteman Cancer Center and Case Comprehensive Cancer Center at Case Western Reserve University in Cleveland. The baseline levels of NfL could distinguish patients who did not develop neurotoxic side effects from those who developed any degree of such side effects. The researchers plan to continue analyzing data from more patients to see if a larger sample size will allow them to identify patients at risk of mild, moderate or severe complications. The complications vary widely across individuals, and can include anything from difficulty concentrating, memory problems, confusion, difficulty reading, and headaches to seizures, strokes and brain swelling. Doctors manage these complications mainly with high-dose steroids and sometimes with immune modulating treatments that attempt to reduce inflammation. It is extremely helpful to know who is at risk of the most dangerous side effects since these therapies can, unfortunately, blunt the anti-cancer effect of the CAR-T cells, and doctors would prefer to avoid using them whenever possible. Another mystery is that the elevated NfL levels are present beforehand and remain mostly stable even as some patients develop and then recover from neurotoxic side effects. This suggests that NfL levels indicate something is wrong but don't reflect whatever is taking place to cause the patients' complications. "We're just seeing the tip of the iceberg in terms of the actual disease process, and that's where many of our future studies are going," Butt said. "We're trying to get a better sense of what is causing these changes to begin with. And in later stages, even after symptoms have resolved, we still see these elevated NfL levels." Added co-senior author Armin Ghobadi, MD, an associate professor of medicine and clinical director of the Center for Gene and Cellular Immunotherapy at Washington University School of Medicine and Siteman Cancer Center: "We have a study ongoing at Siteman to see if, in fact, these patients continue to have subtle symptoms in terms of cognitive changes or deficits that persist long term." (AF) Read the full article

[mrunalnerkarblog]

Personalized Gene Therapy Treatments for Cancer Market : Quantitative Market Analysis, Current and Future Trends

Gene therapy involves insertion of genetic material into cells of the patients to provide them a new function or to restore the missing or inappropriate functioning of the cells due to cancer or gene mutations. Scientists have created personalized medicines that are used to learn about a person’s genetic makeup and untangle the biologic nature of the patient’s cancerous cells for carrying out such therapies. Depending on the type of therapy, personalized gene therapy treatments for cancer market is differentiated into two segments which are as follows:

Targeted treatments

Pharmacogenomics

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On the basis of application, the personalized gene therapy treatments for cancer market is analyzed into:

Breast Cancer

Leukemia

Head & Neck Cancer

Prostate Cancer

Pancreatic Cancer

Leukemia Cancer

Melanoma

Ovarian Cancer

Brain Cancer

Colorectal Cancer

Lung Cancer

Liver Cancer

Bladder Cancer

Lymphoma

 Personalized Gene Therapy Treatments for Cancer Market Potential Applications

Targeted treatments are focused on cancer specific genes, tissues or the protein environment that contribute towards the cancer survival and growth. Researchers identify new targeted cells and develop and test new drugs and medications for such targets as per patient needs. In targeted treatments, the tumor cells themselves are targeted to cure cancer. Breast cancer, gastrointestinal stromal tumor, colorectal cancer, kidney cancer, melanoma, lung cancer, brain cancer, multiple myeloma, certain childhood cancers and lymphoma, and leukemia are the common types of cancers for which targeted treatments are applied.

Pharmacogenomics, on the other hand, affect the processes occurring in the body and drug responses. The difference in the processes influences the safety and efficacy of a drug. The basic principle behind the treatment is to activate the immune system cells that could attack and destroy the cancerous cells. Moreover, in this case, if the patients’ body does not respond to a medication, the drugs stay in the blood stream for longer period of time and may cause severe side effects. Therefore, this type of treatment carries a risk of reaction of drug from person to person, providing targeted treatment a preference over pharmacogenomics.

Personalized gene therapy treatments for cancer market involves evaluation of the developed drugs through clinical trials. Government support and funding and the advantages of personalized gene therapy over other treatment options such as chemotherapy and surgery are the major factors which are projected to drive growth of personalized gene therapy treatments for cancer market. For instance, the U.S. government has set up the MD Anderson Cancer Center Sheikh Khalifa Bin Zayed Al Nahyan Institute for Personalized Cancer Therapy in Texas to support preclinical research and clinical trials for targeted therapy for particular genes. Such government initiatives are encouraging researchers to develop more effective personalized gene therapy treatments for different types of cancer, thus boosting growth of the cancer personalized gene therapy treatments market. However, high costs associated with these treatments and the unavailability of personalized gene therapy treatment for some types of cancers is the major factor that is projected to restrain growth of the personalized gene therapy treatments for cancer market.

Geographically, the personalized gene therapy treatments for cancer market has been analyzed into North America, Europe, Asia Pacific, Latin America, Middle East, and Africa. The major players in the customized gene therapy treatments for cancer market include Amgen, Inc., SynerGene Therapeutics, Inc., Chengdu Shi Endor Biological Engineering Technology Co., Ltd., Cold Genesys, Inc., Takara Bio, Inc., Bellicum Pharmaceuticals, Inc., Ziopharm Oncology, Inc., OncoSec Medical, Inc., Sevion Therapeutics, Inc., and Burzynski Clinic.

Key Developments

Major government bodies and NGOs are focused on supporting R&D in personalized gene therapies for cancer. For instance, in August 2019, The National Cancer Institute of the National Institutes of Health (US) awarded Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis with a US$ 15 million grant in a research to investigate the genetic changes that cause acute myeloid leukemia.

Similarly, in August 2019, The Leukemia & Lymphoma Society (LLS) increased pediatric cancer research funding through US$ 50 million Children’s Initiative by adding 20 new grants valued at over US$ 13.8 million to its 2019 portfolio. The LLS aims for the treatment of leukemia & lymphoma patients with multiple targeted therapies simultaneously at up to 200 clinical sites worldwide.

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Major institutes are focused on R&D of novel approaches in personalized gene therapies for cancer. For instance, in August 2019, researchers from the Institute of Cancer Research, London, reported use of Artificial Intelligence and Machine Learning to identity five new subtypes of breast cancer. The development reported in the journal NPJ Breast Cancer is expected to aid in development of personalized diagnostics and gene therapies.

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[appro880]

Don’t Ever Limit Your Abilities to Just Sports and Entertainment. There’s a Whole World Out there Beyond Those Two Pursuits...

[lomanstravels]

Cancer Treatment Day #8

Siteman Cancer Center, a part of BJC Hospital (Barnes/Jewish/Children’s) is an amalgam of many hospitals including a Christian in there someplace. Believe they actually went with BJCC for a time. Anyway, this is also tied in closely with Washington University on the other end of Forest Park. 

In the Radiation Oncology Department they wall display showing their history which dates back to 1931.

It’s amazing to think that the process started almost 100 years ago. The initial blast of radiation, while targeting the tumor, also negatively affected neighboring healthy tissue and organs. Special lead plates and cones were developed but not 100% effective. It wasn’t until later in the 1950′s that the use of the Cyclotron began.

Invented by Ernest Lawrence at UC Berkeley in the 1930′s, it is a type of particle accelerator. It accelerates charged particles out from a vacuum chamber and held in a spiral pattern by a magnetic field. Lawrence was awarded the Nobel Prize in Physics in 1939 for his invention.

[elemexecomigo]

More therapy dogs return to Siteman Cancer Center - fox2now.com

More therapy dogs return to Siteman Cancer Center  fox2now.com from "dogs" - Google News https://ift.tt/3xMhioJ via IFTTT