#polycaprolactone

[acumenresearchandconsulting]

The Polycaprolactone Market Size accounted for USD 482.6 Million in 2022 and is estimated to achieve a market size of USD 1,327.6 Million by 2032 growing at a CAGR of 10.7% from 2023 to 2032.

[harshnews]

Polycaprolactone (PCL) Market Size, Share, Trends, Opportunities, Key Drivers and Growth Prospectus

"Global Polycaprolactone (PCL) Market' – Industry Trends and Forecast to 2029

Global Polycaprolactone (PCL) Market, By Form (Pellets, Nanosphere, and Microsphere), Production Method (Ring Opening Polymerization and Polycondensation of Carboxylic Acid), Application (Thermoplastic Polyurethane and Healthcare) – Industry Trends and Forecast to 2031.

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**Segments**

- **Application:** In terms of application, the PCL market can be segmented into healthcare, automotive, textiles, packaging, and others. The healthcare segment is expected to dominate the market due to the growing use of Polycaprolactone in the production of medical devices, drug delivery systems, and tissue engineering applications. The automotive segment is also anticipated to witness significant growth as PCL is used in the production of lightweight components, reducing fuel consumption and emissions.

- **End-Use Industry:** Based on end-use industry, the PCL market can be segmented into pharmaceutical, automotive, construction, and others. The pharmaceutical industry is a major consumer of PCL owing to its biocompatibility and biodegradable properties, making it ideal for medical applications. The automotive industry is also a key end-use industry for PCL due to its usage in manufacturing parts, components, and coatings.

- **Region:** Geographically, the global PCL market can be segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America is expected to dominate the market due to the presence of key players and technological advancements in the region. The Asia Pacific region is also projected to experience substantial growth attributed to the increasing demand for PCL in various industries such as healthcare, automotive, and packaging.

**Market Players**

- Corbion - Perstorp

The key players in the Polycaprolactone (PCL) market include Corbion and Perstorp. Corbion is a leading supplier of biobased products, including PCL, catering to various industries such as healthcare and packaging. Perstorp is another prominent player known for its high-quality PCL products used in medical applications and other sectors. These market players are focusing on research and development activities to innovate new products and expand their market presence.

https://www.databridgemarketresearch.com/reports/global-polycaprolactone-pcl-marketThe Polycaprolactone (PCL) market is poised for significant growth across various segments and regions. In terms of applications, the healthcare segment stands out as a key driver for market expansion. The increasing utilization of PCL in the production of medical devices, drug delivery systems, and tissue engineering applications is propelling the growth of this segment. Additionally, the automotive sector is expected to witness substantial growth due to the lightweight nature of components produced using PCL, which aids in reducing fuel consumption and emissions. Moreover, PCL finds its application in textiles, packaging, and other industries, further diversifying its market reach.

When considering end-use industries, pharmaceuticals emerge as the largest consumer of PCL. The biocompatibility and biodegradable properties of PCL make it a preferred choice for medical applications within the pharmaceutical sector. Furthermore, the automotive industry also significantly contributes to the demand for PCL, utilizing it in the manufacturing of various parts, components, and coatings, thus driving growth in this particular segment. The construction sector and other industries also play a role in the uptake of PCL for diverse applications.

From a regional perspective, North America is expected to lead the global PCL market due to the presence of key market players and advancements in technology within the region. The well-established healthcare and automotive industries in North America further boost the demand for PCL in various applications. The Asia Pacific region is also set for substantial growth in the PCL market, driven by the increasing demand across industries such as healthcare, automotive, and packaging. The region's rapid industrialization and economic development are contributing to the rising adoption of PCL in different sectors.

Corbion and Perstorp emerge as prominent players in the PCL market, known for their high-quality products catering to diverse industries. Corbion's expertise in biobased products, including PCL, positions them as a key supplier to sectors like healthcare and packaging. Perstorp, on the other hand, is recognized for**Segments**

Global Polycaprolactone (PCL) Market, By Form (Pellets, Nanosphere, and Microsphere), Production Method (Ring Opening Polymerization and Polycondensation of Carboxylic Acid), Application (Thermoplastic Polyurethane and Healthcare) – Industry Trends and Forecast to 2031.

In the PCL market, various segments play a crucial role in driving growth and market expansion. The application segment is diverse, including healthcare, automotive, textiles, packaging, and others. The healthcare sector is anticipated to lead the market, fueled by the increasing use of PCL in medical devices, drug delivery systems, and tissue engineering applications. Similarly, the automotive segment is expected to experience significant growth due to the utilization of PCL in lightweight components, contributing to reduced fuel consumption and emissions. Moreover, the versatility of PCL extends to industries like textiles, packaging, and more, further expanding its market reach.

When analyzing the end-use industry segmentation, pharmaceuticals emerge as a major consumer of PCL, primarily due to its biocompatibility and biodegradable nature, making it ideal for medical applications. The automotive industry also plays a significant role in driving the demand for PCL, utilizing it in the manufacturing of parts, components, and coatings. Additionally, sectors such as construction and others contribute to the diverse applications of PCL, further enhancing its market presence across various industries.

From a regional perspective, North America is poised to dominate the global PCL

Key points covered in the report: -

The pivotal aspect considered in the global Polycaprolactone (PCL) Market report consists of the major competitors functioning in the global market.

The report includes profiles of companies with prominent positions in the global market.

The sales, corporate strategies and technical capabilities of key manufacturers are also mentioned in the report.

The driving factors for the growth of the global Polycaprolactone (PCL) Market are thoroughly explained along with in-depth descriptions of the industry end users.

The report also elucidates important application segments of the global market to readers/users.

This report performs a SWOT analysis of the market. In the final section, the report recalls the sentiments and perspectives of industry-prepared and trained experts.

The experts also evaluate the export/import policies that might propel the growth of the Global Polycaprolactone (PCL) Market.

The Global Polycaprolactone (PCL) Market report provides valuable information for policymakers, investors, stakeholders, service providers, producers, suppliers, and organizations operating in the industry and looking to purchase this research document.

Table of Content:

Part 01: Executive Summary

Part 02: Scope of the Report

Part 03: Global Polycaprolactone (PCL) Market Landscape

Part 04: Global Polycaprolactone (PCL) Market Sizing

Part 05: Global Polycaprolactone (PCL) Market Segmentation by Product

Part 06: Five Forces Analysis

Part 07: Customer Landscape

Part 08: Geographic Landscape

Part 09: Decision Framework

Part 10: Drivers and Challenges

Part 11: Market Trends

Part 12: Vendor Landscape

Part 13: Vendor Analysis

The investment made in the study would provide you access to information such as:

Polycaprolactone (PCL) Market [Global – Broken-down into regions]

Regional level split [North America, Europe, Asia Pacific, South America, Middle East & Africa]

Country-wise Market Size Split [of important countries with major market share]

Market Share and Revenue/Sales by leading players

Market Trends – Emerging Technologies/products/start-ups, PESTEL Analysis, SWOT Analysis, Porter’s Five Forces, etc.

Market Size

Market Size by application/industry verticals

Market Projections/Forecast

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[cosmicanger]

Emir Šehanović, Synthetic Attraction. Recontextualized art installation for Cu29 gallery (2023), originally presented at Space O+A Art Event – Tokyo, Japan. Polycaprolactone, artificial flowers, PVC fabric, neon tubes and aluminium pipes. Dimensions: 250cm x 130cm x 130cm

[materialsscienceandengineering]

Researchers use architected auxetics to achieve 300 times more flexibility in new 3D printing design

There are young children celebrating the holidays this year with their families, thanks to the 3D-printed medical devices created in the lab of Georgia Tech researcher Scott Hollister. For more than 10 years, Hollister and his collaborators have developed lifesaving, patient-specific airway splints for babies with rare birth defects. These personalized Airway Support Devices are made of a biocompatible polyester called polycaprolactone (PCL), which has the advantage of being approved by the Food and Drug Administration. Researchers use selective laser sintering to heat the powdered polyester, which binds together as a solid structure. Devices made of PCL have a great safety record when implanted into patients. Unfortunately, PCL has the disadvantage of having relatively stiff and linear mechanical properties, which means this promising biomaterial has yet to be applied functionally to some other critical biomedical needs, such as soft tissue engineering. How do you make a firm thermoplastic into something flexible, and possibly capable of growing with the patient? Hollister's lab has figured out how.

Read more.

[livglam06]

Thread Lift Treatment Cost in Bangalore

Thread lift is a minimally invasive cosmetic procedure that offers a subtle but visible lift to sagging skin, often referred to as the “lunchtime facelift.” It’s gaining popularity in cities like Bangalore for its quick recovery time and natural-looking results.

In Bangalore, the cost of a thread lift treatment generally ranges from ₹25,000 to ₹1,00,000, depending on several factors. The price varies based on the number of threads used, the area being treated (face, neck, or jawline), the clinic’s reputation, and the experience of the dermatologist or plastic surgeon.

Types of threads also influence pricing. PDO (Polydioxanone), PLLA (Poly-L-Lactic Acid), and PCL (Polycaprolactone) are commonly used, with PCL being the most long-lasting and often more expensive. A basic mid-face thread lift may start at ₹30,000, while a full-face lift with premium threads could cost upwards of ₹80,000 or more.

It's essential to consult with a certified and experienced practitioner to determine the right approach for your skin type and aesthetic goals. Most clinics in Bangalore offer free consultations, and some may also include aftercare services in the treatment package.

Overall, while the cost can vary, Bangalore offers competitive pricing for thread lifts without compromising on quality, especially when compared to international standards.

[vishvajit123]

Global Wound Closure Strips Market by Type, Featuring Market Size, Segmental Breakdown, Regional Insights, Company Share Analysis, Leading Player Profiles, and Forecast from 2025 to 2035

Industry Outlook for Wound Closure Strips Market

The global wound closure strips market reached USD 257.23 million in 2024 and is projected to hit USD 478.26 million by 2035, expanding at a compound annual growth rate (CAGR) of approximately 7.65% from 2025 to 2035. This market includes advanced medical devices focused on securing surgical sites and managing minor wounds without sutures or staples. These adhesive strips are designed to align skin edges and enhance the healing process, often resulting in less visible scars. They are widely used by healthcare professionals to close surgical incisions and minor lacerations.

Wound closure strips come in various materials such as polyester, nylon, and nonwoven fabrics, all incorporating hypoallergenic adhesives. The increasing demand for non-invasive treatment options, driven by rising healthcare needs globally, is significantly fueling the growth of this market.

Get free sample Research Report - https://www.metatechinsights.com/request-sample/2224

Biodegradable Materials Boosting Eco-Friendly Product Development

The development of biodegradable wound closure strips is transforming the market landscape. Materials like polylactic acid (PLA) and polycaprolactone (PCL) are being utilized to produce eco-conscious wound care products that naturally decompose, minimizing environmental impact. These strips not only offer sustainability benefits but also support rapid wound recovery and reduce infection risks. According to research by the National Institutes of Health (NIH), the integration of biodegradable materials is expected to lead to improved patient outcomes and meet the growing demand for sustainable healthcare solutions.

Rising Popularity of Cosmetic Procedures Fuels Demand for Scar-Minimizing Strips

With the surge in cosmetic and reconstructive procedures, the need for wound closure strips that reduce scarring has increased significantly. Patients undergoing surgeries such as plastic or skin resurfacing prioritize aesthetics, making scar-reducing strips an ideal solution. These strips help optimize healing while improving post-procedural cosmetic outcomes. Research by the NIH highlights that concerns about scarring post-cosmetic surgery are driving adoption of advanced wound closure products that deliver both functionality and improved aesthetics.

High Costs Hindering Access in Cost-Sensitive Regions

Despite their benefits, the high cost of specialized wound closure strips limits their adoption in regions with constrained healthcare budgets. This poses a significant barrier to market penetration in low-income and developing countries, where cheaper traditional wound care methods are often preferred. The World Health Organization (WHO) emphasizes that financial constraints in these regions restrict access to modern wound care technologies, including advanced adhesive strips.

Customizable Strips for Sensitive Skin Driving Innovation

Innovations in patient-specific wound closure strips are opening new market opportunities. Traditional adhesive strips may not be suitable for individuals with sensitive or aging skin, pediatric patients, or those with dermatological issues. The development of customizable strips using hypoallergenic materials and adjustable adhesion levels ensures comfort and effective healing. These patient-centric solutions are gaining popularity, contributing to better recovery outcomes and higher satisfaction rates. As demand grows for personalized medical care, the adoption of customizable strips continues to expand across diverse patient groups.

Chronic Wound Care Segment Creating New Growth Opportunities

The increasing prevalence of chronic wounds such as diabetic foot ulcers, pressure ulcers, and venous leg ulcers has led to rising demand for wound closure strips tailored for long-term wound management. These strips offer high adhesion, effective moisture control, and scarring prevention. NIH data reveals that chronic wounds affect over 6.5 million individuals in the United States, highlighting the urgent need for effective wound closure technologies. The chronic wound care segment presents a lucrative opportunity for manufacturers to expand their product portfolios and address this growing healthcare challenge.

Expert Insight on Market Trends

Dr. Patricia Lee, Senior Dermatologist at the Cleveland Clinic, emphasized the evolution of wound closure strips: “The evolution of wound closure strips has been remarkable in terms of material innovation, providing enhanced adhesion, breathability, and comfort for patients. These strips are not only effective for simple wounds but are also being adapted for use in more complex applications such as post-surgical care. Their ability to promote faster healing with minimal scarring is driving their increasing adoption in wound care practices.”

Type Analysis of Wound Closure Strips Market

The market is segmented by type into single-use strips, reusable strips, and others. Single-use wound closure strips dominate the market due to their high adoption in hospitals, clinics, and emergency care settings. These strips are favored for their ease of use, hygienic benefits, and reduced risk of cross-contamination. Their disposable nature eliminates the need for sterilization, saving time and resources while ensuring patient safety.

Read Full Research Report https://www.metatechinsights.com/industry-insights/wound-closure-strips-market-2224

Material Analysis Highlights Nonwoven Fabrics as Market Leader

By material, the market is categorized into polyester, nylon, nonwoven fabrics, and others. Nonwoven fabric-based strips currently lead the market due to their superior flexibility, breathability, and comfort. These properties make them ideal for surgical applications, particularly on sensitive skin. Their ability to conform to wound contours and provide a secure seal enhances the healing process and makes them a preferred choice among healthcare professionals.

Regional Insights into Wound Closure Strips Market

North America holds the largest share of the wound closure strips market, driven by a high volume of surgical procedures, increasing traumatic injuries, and growing demand for advanced wound management technologies. Established healthcare infrastructure, high medical expenditure, and favorable reimbursement policies contribute to the region's market dominance. The presence of leading medical device manufacturers and continuous product innovation further accelerates growth.

The Asia Pacific region is experiencing rapid market expansion due to a rising number of surgeries, increasing incidence of chronic wounds, and healthcare infrastructure improvements. Markets in China, India, and Japan are particularly witnessing increased adoption of minimally invasive procedures and scar-minimizing strips. Government investments in wound care and growing public awareness are also fueling regional market growth.

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Competitive Landscape and Key Developments

The wound closure strips market features strong competition among top players such as 3M Company, Johnson & Johnson, Smith & Nephew plc, Medtronic plc, and B. Braun Melsungen AG. These companies focus on product innovation, strategic collaborations, and the development of biodegradable and scar-reducing solutions to meet evolving patient needs.

Additional contributors like Molnlycke Health Care AB, Cardinal Health Inc., and Medline Industries LP are expanding distribution networks in emerging markets. Companies such as Dynarex Corporation, Integra LifeSciences Corporation, and BSN Medical GmbH are investing heavily in research and development to introduce next-generation wound care solutions. The competitive dynamics are driven by mergers, acquisitions, and new product launches aimed at expanding market share and driving technological advancements.

In September 2024, Sylke, a silk-based surgical dressing developed by Dr. John Mofid, received the Allure Best of Beauty Breakthrough Award. This product enhances patient comfort, improves scar appearance, and reduces skin irritation compared to traditional dressings, reflecting the ongoing innovation within the wound closure strips market.

[medoja]

Biodegradable Implants: The Role of Sustainable Biomaterials in Surgery

In recent years, the medical field has been shifting toward more sustainable and patient-friendly solutions. One area that’s gaining momentum is the use of biodegradable implants, made possible by innovations in sustainable biomaterials. These implants are designed to naturally break down and be absorbed by the body over time, eliminating the need for removal surgeries and reducing medical waste.

What Are Biodegradable Implants?

Biodegradable implants are medical devices made from bio-based materials that gradually dissolve in the body after fulfilling their purpose. Commonly used in orthopedic surgeries, sutures, and drug delivery systems, these implants offer a safer and more sustainable alternative to traditional metal or plastic implants.

How Sustainable Biomaterials Make a Difference

Sustainable biomaterials are derived from renewable sources like polylactic acid (PLA), polycaprolactone (PCL), and natural polymers such as collagen and chitosan. These materials are biocompatible, meaning they interact safely with human tissue, and they biodegrade naturally, reducing long-term risks and environmental impact.

The use of eco-friendly materials in healthcare is not just about sustainability; it also improves patient outcomes. Since biodegradable implants eliminate the need for follow-up removal procedures, they reduce the risk of infection, lower healthcare costs, and enhance recovery times.

Advantages of Biodegradable Implants in Surgery

Improved Patient Comfort: Lightweight and body-compatible, biodegradable implants adapt better to patient physiology.

Minimized Need for Secondary Surgery: Once their job is done, these implants dissolve, eliminating the need for removal.

Reduced Risk of Infection: Less invasive procedures mean lower chances of post-surgical complications.

Environmental Benefits: Less reliance on permanent, synthetic materials leads to a reduction in medical and plastic waste.

Current Applications in the Medical Field

Biodegradable implants are being used in a wide range of medical specialties:

Orthopedics: Screws, pins, and plates that support healing bones.

Cardiology: Biodegradable stents that naturally dissolve after restoring blood flow.

Suturing Materials: Threads that naturally break down post-healing.

Drug Delivery Systems: Implants that release medication over time and then dissolve.

The Future of Sustainable Biomaterials in Medicine

With advancements in biomedical engineering, researchers are continually exploring new eco-conscious medical solutions. The future holds promise for smart biodegradable implants that not only dissolve but also monitor healing and adapt to changes in the body.

Final Thoughts

As the demand for sustainable healthcare solutions grows, biodegradable implants made from sustainable biomaterials are paving the way for a safer, greener medical industry. These innovations represent a powerful combination of patient care and environmental responsibility, proving that medicine can be both high-tech and eco-friendly.

By embracing biodegradable solutions, we’re not just healing bodies—we’re also helping to heal the planet.

[anviduby]

Bone Regeneration Market Growth Driven by Advancements in Biomaterials, Stem Cell Therapy, and 3D Printing

The global bone regeneration market is experiencing remarkable growth, fueled by significant advancements in biomaterials, stem cell therapy, and 3D printing. As the prevalence of bone-related disorders such as osteoporosis, fractures, and bone defects rises, the demand for innovative and effective bone regeneration solutions continues to increase. In parallel, the bone densitometer market is expanding due to the growing need for precise bone density assessment, further driving advancements in regenerative treatments.

Advancements in Biomaterials Enhancing Bone Regeneration

Biomaterials play a crucial role in bone regeneration, providing the necessary scaffolding to support bone growth and healing. Over the years, researchers have developed advanced biomaterials that mimic the natural extracellular matrix, promoting faster and more efficient bone healing. Some of the most promising materials include:

Bioceramics: These include calcium phosphate-based materials such as hydroxyapatite and tricalcium phosphate, which closely resemble the mineral composition of natural bone, making them highly effective in bone grafting procedures.

Biodegradable Polymers: Materials such as polylactic acid (PLA) and polycaprolactone (PCL) are widely used in scaffolds as they provide temporary support and degrade over time as new bone forms.

Bioactive Glass: This innovative material has been shown to stimulate bone cell activity and promote regeneration by releasing beneficial ions into the surrounding tissue.

The continuous improvements in biomaterials have led to better biocompatibility, enhanced mechanical properties, and increased effectiveness in treating bone defects.

Stem Cell Therapy: A Breakthrough in Bone Regeneration

Stem cell therapy is emerging as a game-changing technology in bone regeneration. Mesenchymal stem cells (MSCs), derived from sources such as bone marrow, adipose tissue, and umbilical cord blood, have demonstrated the ability to differentiate into osteoblasts, the cells responsible for bone formation. Stem cell-based approaches offer several advantages, including:

Faster Healing: Stem cells accelerate the bone repair process by directly contributing to new bone formation and releasing growth factors that enhance tissue regeneration.

Reduced Risk of Rejection: Since stem cells can be harvested from the patient’s own body (autologous transplantation), the likelihood of immune rejection is significantly minimized.

Minimally Invasive Procedures: Advances in stem cell therapy have led to less invasive techniques for delivering cells to the affected area, reducing recovery time and post-surgical complications.

Despite its potential, challenges such as scalability, ethical concerns, and regulatory approvals need to be addressed for stem cell therapy to become a mainstream treatment in bone regeneration.

3D Printing Revolutionizing Bone Reconstruction

3D printing technology is reshaping the landscape of bone regeneration by enabling the production of patient-specific bone grafts and implants. With the ability to create highly customized and complex structures, 3D printing offers numerous benefits, including:

Personalized Implants: Using patient imaging data, 3D printers can produce implants that perfectly match the size, shape, and structure of the missing bone, leading to better integration and functionality.

Enhanced Biocompatibility: Advanced 3D printing techniques allow the incorporation of bioactive materials and growth factors, improving the body’s natural healing response.

Cost-Effective Solutions: Traditional bone grafting methods can be expensive and time-consuming. 3D printing streamlines the process, reducing costs and improving accessibility to cutting-edge treatments.

With ongoing research and technological refinements, 3D printing is expected to further revolutionize bone regeneration, making treatments more effective and widely available.

Market Outlook and Future Trends

The bone regeneration market is poised for substantial growth, driven by an aging population, increasing incidences of bone disorders, and continuous advancements in regenerative medicine. Companies and research institutions are investing heavily in R&D to develop next-generation biomaterials, enhance stem cell therapies, and refine 3D printing technologies.

Moreover, the integration of artificial intelligence (AI) and digital health solutions is expected to further optimize bone regeneration procedures, enabling better diagnosis, treatment planning, and patient monitoring. As these technologies continue to evolve, the bone regeneration market will witness significant expansion, providing patients with more efficient, minimally invasive, and highly effective treatment options.

Conclusion

The convergence of biomaterials, stem cell therapy, and 3D printing is revolutionizing the bone regeneration market. These cutting-edge advancements are improving patient outcomes, reducing recovery times, and offering innovative solutions for bone repair and reconstruction. With continued research and technological progress, the future of bone regeneration looks promising, offering hope to millions of individuals suffering from bone-related ailments worldwide.

[sunaleisocial]

Engineers develop a better way to deliver long-lasting drugs

New Post has been published on https://sunalei.org/news/engineers-develop-a-better-way-to-deliver-long-lasting-drugs/

Engineers develop a better way to deliver long-lasting drugs

MIT engineers have devised a new way to deliver certain drugs in higher doses with less pain, by injecting them as a suspension of tiny crystals. Once under the skin, the crystals assemble into a drug “depot” that could last for months or years, eliminating the need for frequent drug injections.

This approach could prove useful for delivering long-lasting contraceptives or other drugs that need to be given for extended periods of time. Because the drugs are dispersed in a suspension before injection, they can be administered through a narrow needle that is easier for patients to tolerate.

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“We showed that we can have very controlled, sustained delivery, likely for multiple months and even years through a small needle,” says Giovanni Traverso, an associate professor of mechanical engineering at MIT, a gastroenterologist at Brigham and Women’s Hospital (BWH), an associate member of the Broad Institute, and the senior author of the study.

The lead authors of the paper, which appears today in Nature Chemical Engineering, are former MIT and BWH postdoc Vivian Feig, who is now an assistant professor of mechanical engineering at Stanford University; MIT graduate student Sanghyun Park; and Pier Rivano, a former visiting research scholar in Traverso’s lab.

Easier injections

This project began as part of an effort funded by the Gates Foundation to expand contraceptive options, particularly in developing nations.

“The overarching goal is to give women access to a lot of different formats for contraception that are easy to administer, compatible with being used in the developing world, and have a range of different timeframes of durations of action,” Feig says. “In our particular project, we were interested in trying to combine the benefits of long-acting implants with the ease of self-administrable injectables.”

There are marketed injectable suspensions available in the United States and other countries, but these drugs are dispersed throughout the tissue after injection, so they only work for about three months. Other injectable products have been developed that can form longer-lasting depots under the skin, but these typically require the addition of precipitating polymers that can make up 23 to 98 percent of the solution by weight, which can make the drug more difficult to inject.

The MIT and BWH team wanted to create a formulation that could be injected through a small-gauge needle and last for at least six months and up to two years. They began working with a contraceptive drug called levonorgestrel, a hydrophobic molecule that can form crystals. The team discovered that suspending these crystals in a particular organic solvent caused the crystals to assemble into a highly compact implant after injection. Because this depot could form without needing large amounts of polymer, the drug formulation could still be easily injected through a narrow-gauge needle.

The solvent, benzyl benzoate, is biocompatible and has been previously used as an additive to injectable drugs. The team found that the solvent’s poor ability to mix with biological fluids is what allows the solid drug crystals to self-assemble into a depot under the skin after injection.

“The solvent is critical because it allows you to inject the fluid through a small needle, but once in place, the crystals self-assemble into a drug depot,” Traverso says.

By altering the density of the depot, the researchers can tune the rate at which the drug molecules are released into the body. In this study, the researchers showed they could change the density by adding small amounts of a polymer such as polycaprolactone, a biodegradable polyester.

“By incorporating a very small amount of polymers — less than 1.6 percent by weight — we can modulate the drug release rate, extending its duration while maintaining injectability. This demonstrates the tunability of our system, which can be engineered to accommodate a broader range of contraceptive needs as well as tailored dosing regimens for other therapeutic applications,” Park says.

Stable drug depots

The researchers tested their approach by injecting the drug solution subcutaneously in rats and showed that the drug depots could remain stable and release drug gradually for three months. After the three-month study ended, about 85 percent of the drug remained in the depots, suggesting that they could continue releasing the drugs for a much longer period of time.

“We anticipate that the depots could last for more than a year, based on our post-analysis of preclinical data. Follow-up studies are underway to further validate their efficacy beyond this initial proof-of-concept,” Park says.

Once the drug depots form, they are compact enough to be retrievable, allowing for surgical removal if treatment needs to be halted before the drug is fully released.

This approach could also lend itself to delivering drugs to treat neuropsychiatric conditions as well as HIV and tuberculosis, the researchers say. They are now moving toward assessing its translation to humans by conducting advanced preclinical studies to evaluate self-assembly in a more clinically relevant skin environment. “This is a very simple system in that it’s basically a solvent, the drug, and then you can add a little bit of bioresorbable polymer. Now we’re considering which indications do we go after: Is it contraception? Is it others? These are some of the things that we’re starting to look into as part of the next steps toward translation to humans,” Traverso says.

The research was funded, in part, by the Gates Foundation, the Karl van Tassel Career Development Professorship, the MIT Department of Mechanical Engineering, a Schmidt Science Fellows postdoctoral fellowship, the Rhodes Trust, a Takeda Fellowship, a Warren M. Rohsenow Fellowship, and a Kwangjeong Educational Foundation Fellowship.

[marketingreportz]

Bio-based Resins Market - Forecast(2025 - 2031)

Bio-Based Resin Overview

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COVID Impact

The sudden outbreak of coronavirus pandemic has hit the packaging industry hard, as during the month from March to June in 2020 almost every country was in the lockdown mode owing to which, e-commerce companies have also stopped their services for months. So, with the decline in packaging sector the bio-based resin market has also restrained.

Report Coverage

The report: “Bio-Based Resin Market — Forecast (2021–2026)”, by IndustryARC, covers an in-depth analysis of the following segments of the bio-based resin market.

By Product Type — Biodegradables (Starch-based, Cellulose Derivatives, Polyvinyl Alcohol, Bio Epoxy Resins, Polylactic acid (PLA), Polyglycolic acid (PGA), Polycaprolactone (PCL), Polyhydroxybutyrate (PHB), Polybutylene Succinate (PBS), Polyhydroxyalkanoates (PHA), Polyanhydrides and Others) and Non-biodegradables (Biopolyethylene Terephthalate (PET), Biopolyethylene, Biopolyamides, Biopolyols and Polyurethane, Biopolytrimethylene Terephthalate (PTT), Bio-Polypropylene (PP) and Others).

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By End Use Industry — Packaging, Aviation, Construction (Residential, Commercial, Industrial, Infrastructure), Automotive (Passenger Cars, Light Commercial Vehicle, Heavy Commercial Vehicle), Food & Beverage, Agriculture, Healthcare, Household and Consumer Goods and Others.

By Geography — North America (U.S., Canada, and Mexico), Europe (U.K., Germany, Italy, France, Spain, Netherlands, Russia, Belgium, and Rest of Europe), Asia Pacific (China, Japan, India, South Korea, ANZ, Indonesia, Taiwan, Malaysia, and Rest of Asia Pacific), South America (Brazil, Argentina, Colombia, Chile, and Rest of South America) and RoW (Middle East and Africa).

Key Takeaways

Asia-Pacific dominates the bio-based resin market owing to increasing demand from end use industries such as packaging, construction and others.

The growing demand for bio-based resin for stable timber construction, is likely to aid in the market growth of bio-based resin.

The emergence of bio-based resin as an alternative for petroleum-derived polymers is expected to drive the market for bio-based resin in the upcoming years.

Higher cost of biobased resin will create hurdles for the bio-based resin in the near future.

For more details on this report — Request for Sample

Bio-Based Resin Market Segment Analysis — By Product Type

Biodegradable segment held the largest share in the Bio-Based Resin market in the year 2020 and is expected to grow at a CAGR of 5.6% during the forecast period. Biodegradable resins are ideal for producing disposable packaging materials. They are capable of playing a key role in sustainable plastic production. Products based on biodegradable plastics are often reflected as savior products as, shifting to these materials helps to lessen carbon dioxide, greenhouse gas emission levels, energy of manufacturing, and amount of waste produced and create opportunity for new plastic industries. However, they are heavier than the petroleum-based polymers. While they will never completely eliminate the problem of plastic waste (since they are not suitable for all product applications), biodegradables can nevertheless be an important tactic in reducing pollution and waste in some instances.

Bio-Based Resin Market Segment Analysis — By Application

Packaging sector has been the primary market for Bio-Based Resin in the year 2020 and is expected to grow at a CAGR of 4.5% during the forecast period. Bio-polyethylene terephthalate, polylactic acid (PLA) and others are driving the packaging production and market demand for biobased resin. Polylactic Acid (PLA) are primarily used in the food, industrial, and medical industries. PLA originates from renewable sources as a result of eco-friendly fermentation and degrades into non-toxic content.

In addition, lignin as an organic polymer increases the barrier properties of finished products, especially against UV rays. Whereas, according to information provided by World Packaging Organization (WPO), the turnover of global packaging industry is more than $500 billion in the year 2019 and is expected to grow more in the upcoming years. Hence with the increase in market growth of packaging industry, the bio-based resin market is expected to grow.

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Bio-Based Resin Market Segment Analysis — By Geography

APAC dominated the Bio-Based Resin market in the year 2020 holding share of 41% during the forecast period. China and India are the major countries in this region, owing to the great demand automotive, packaging and other industries. Bio-based resin are used in automotive sector for manufacturing of non-structural interior components, including wood trim, seat fillers, seat backs, headliners, interior panels, dashboards and thermoacoustic insulation.

So, with the growing manufacturing of automotive around the world the demand for bio-based resin is expected to grow in this sector. According to the OICA’s (International Organization of Motor Vehicle Manufacturers), sales statistics, the automotive production in Asia/Oceania/Middle East region has increased by 1.34% from 2015 to 2019. However, China was the largest producer of automotive in the world, while India was the 5th largest of automotive in the year 2019. Hence, with the growing demand for automotive will eventually led to the market growth the bio-based resin during the forecast period.

Bio-Based Resin Market Drivers

Emergence of Electric Vehicle

Bio-based resin already have a major demand in the automotive sector, mainly for interior products. But with the emergence electric vehicles, the bio-based resin market is expected to grow, while the growing potential demand for electric vehicle will eventually boost the demand for bio-based resin in electric vehicles. However according to the IEA’s Global EV outlook 2020, the global electric car stock has increased by 2.1 million in the year 2019, as compared with 2018. So, with the growing demand for electric vehicles around the world, the bio-based resin market will also drive.

Alternative for Petroleum-Based Products

Exploration and expansion of new chemical/material substitutes is critical in reducing mankind’s dependence on fossil fuel energy in the face of a potential fossil fuel crisis. Whereas bio-based resins (such as PHA, PLA, starch, protein, chitin, chitosan, and PBS) are some of the substitute for petroleum-based products. Furthermore, bio-based polymers are still new, though, they are in continuous development. Hence with the upcoming years the bio-based resin tends to increase.

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Bio-Based Resin Market Challenges

Higher Cost of Bio-Based Resin

Bio-based resin are generally two or three times more expensive than the major conventional plastics such as PE or PET, and their production is plagued by low yields and being expensive. At current technologies it cost nearly 50% more than the traditional petroleum products. These prices may come down in the near future, as technologies improve and source material access becomes cheaper to produce. Hence even being biodegradable and good for environment, the biobased resin cost is making difficult for the manufacturers to survive. This could restrain the market growth of bio-based resin.

Bio-Based Resin Market Landscape

Technology launches, acquisitions and R&D activities are key strategies adopted by players in the Bio-Based Resin market. Major players in the Bio-Based Resin Market are Absecon Mill, Agri-Fibers Inc, Archer Daniel Midland, Ashland Performance Material, BASF SE, Braskem, Cargill Nature Work, Cereplast, Dowdupont, Etech Surf, John Deere, among others.

Acquisitions/Technology Launches

In January 2019, PolyOne Corporation, a premier global provider of specialized polymer materials, services and solutions, has completed the acquisition of Fiber-Line, a global leader in customized engineered fibers and composite materials for $120 million.

In January 2019, Archer Daniels Midland Company has successfully completed its $ US 1.84 (€1.544) billion acquisition of Neovia, creating a global leader in value-added products and solutions for both production and companion animals.

Relevant Reports

Bio-based Platform Chemicals Market — Industry Analysis, Market Size, Share, Trends, Application Analysis, Growth And Forecast 2019–2024

Report Code: CMR 43954

Bio-plastics Market — Forecast(2021–2026)

Report Code: CMR 0846

For more Chemicals and Materials related reports, please click here

[kaneinstitute]

The Art of Rejuvenation: Thread Lift as a Revolutionary Facelift Alternative

Aging is an inevitable process that brings about changes in skin elasticity, texture, and overall appearance. While traditional facelift surgery has long been a solution for reversing signs of aging, many individuals are now opting for minimally invasive alternatives. Among these, the thread lift stands out as a highly effective and less intrusive cosmetic procedure that provides a youthful and lifted appearance with minimal downtime. https://medium.com/@itskaneinstitute.com/thread-lift-a-non-surgical-facelift-for-youthful-skin-e7293bc4c7b3/

Understanding the Thread Lift Procedure

A thread lift is a non-surgical cosmetic treatment designed to lift and tighten sagging skin using biodegradable, medical-grade sutures. Unlike traditional facelifts, which involve significant incisions and recovery time, a thread lift offers a minimally invasive approach by placing dissolvable threads beneath the skin to provide immediate lift and long-term collagen stimulation.

The procedure is typically performed on areas prone to sagging, such as:

The mid-face and cheeks

Jowls and jawline

Eyebrows

Neck

Nasolabial folds

The results are subtle but effective, creating a naturally youthful look without the drastic transformation associated with surgery.

How Thread Lifts Work

The procedure begins with a consultation, during which a cosmetic professional assesses the patient’s skin condition and determines the best treatment plan. On the day of the procedure, a local anesthetic is applied to ensure comfort. The practitioner then inserts fine, biodegradable threads under the skin using a small needle or cannula. These threads act as a support structure, lifting the skin while stimulating collagen production. Over time, as the threads dissolve, new collagen continues to provide firmness and elasticity, prolonging the effects of the treatment.

Common materials used for thread lifts include:

Polydioxanone (PDO): Stimulates collagen production and naturally dissolves within 6 months.

Polylactic Acid (PLA): Promotes skin renewal and has longer-lasting effects than PDO threads.

Polycaprolactone (PCL): The most durable thread material, lasting up to two years.

Benefits of a Thread Lift

1. Minimally Invasive and Quick Recovery

Unlike traditional facelifts that require general anesthesia, extensive incisions, and weeks of recovery, a thread lift is performed under local anesthesia and requires minimal downtime. Most patients resume daily activities within 24 to 48 hours.

2. Natural-Looking Enhancement

Thread lifts provide a gentle lift rather than an exaggerated tightening effect, ensuring a refreshed and youthful look while maintaining natural facial expressions.

3. Collagen Stimulation for Long-Term Benefits

One of the most significant advantages of a thread lift is its ability to promote collagen production. As the threads dissolve, they leave behind a firmer, more elastic skin structure that continues to improve over time.

4. Cost-Effective Alternative to Surgery

While traditional facelifts can be expensive, thread lifts are a more affordable option with impressive results. Although not permanent, they provide a worthwhile middle ground between injectables and surgical facelifts.

5. Low Risk and Fewer Complications

Since thread lifts do not require extensive incisions, the risks of scarring, infection, and anesthesia-related complications are significantly reduced.

Ideal Candidates for Thread Lifts

Thread lifts are ideal for individuals who experience mild to moderate sagging in their skin and want a non-surgical solution. The best candidates include:

Individuals between the ages of 30 and 55.

Those who want to improve facial contours without undergoing surgery.

People looking for subtle yet effective facial rejuvenation.

Patients who prefer minimal downtime and quick recovery.

However, those with severe skin laxity or excess loose skin may require a traditional facelift for optimal results.

The Thread Lift Process: Step-by-Step

1. Consultation and Planning

A licensed practitioner evaluates the patient’s skin, discusses expectations, and customizes the thread placement plan based on the patient’s facial structure.

2. Pre-Treatment Preparation

The treatment area is cleaned, and a local anesthetic is applied to numb the skin, ensuring a comfortable procedure.

3. Insertion of Threads

Using a fine needle or cannula, the practitioner carefully places the threads under the skin in a specific pattern to create a lifting effect. Once positioned, the threads are gently adjusted to achieve the desired lift.

4. Immediate Results and Healing

The results are visible immediately, with continued improvement over the following weeks as collagen production increases.

5. Aftercare and Recovery

Patients are advised to avoid excessive facial movements, sleeping on their sides, and strenuous physical activities for the first few days to ensure proper healing.

Potential Risks and Side Effects

While thread lifts are generally safe, some minor side effects may occur, including:

Mild swelling and bruising

Temporary discomfort at the insertion sites

Rare cases of infection or thread visibility under the skin

Slight asymmetry, which typically resolves as the skin settles

Choosing a skilled and experienced practitioner minimizes these risks and enhances the safety and effectiveness of the procedure.

Comparing Thread Lifts with Traditional Facelifts

FeatureThread LiftTraditional FaceliftInvasivenessMinimally invasiveSurgical procedureRecovery Time1-3 daysSeveral weeksLongevity12-24 months5-10 yearsCostMore affordableExpensiveAnesthesiaLocal anesthesiaGeneral anesthesiaRisk FactorLowHigher risk of complications

Frequently Asked Questions

1. How long do thread lift results last?

Results typically last between 12 to 24 months, depending on the type of threads used and the individual’s collagen production.

2. Is a thread lift painful?

The procedure is performed under local anesthesia, minimizing discomfort. Some patients may experience mild soreness afterward, which usually subsides within a few days.

3. Can I combine a thread lift with other treatments?

Yes! Many patients combine thread lifts with Botox, dermal fillers, and laser treatments for enhanced rejuvenation.

4. Are there any restrictions after the procedure?

Patients should avoid excessive facial expressions, heavy lifting, and pressure on the treated area for a few days. Sleeping on the back is recommended to prevent unnecessary strain on the threads.

5. When will I see full results?

While an immediate lift is visible, optimal results appear over 2 to 3 months as collagen production enhances the skin’s firmness.

Thread lifts are a groundbreaking advancement in non-surgical facial rejuvenation. Offering a natural-looking lift, minimal downtime, and collagen stimulation for long-term skin health, they are an excellent choice for individuals seeking a refreshed appearance without the risks of surgery.

If you’re considering a thread lift, consulting a qualified professional will ensure the best results tailored to your facial structure and aesthetic goals. With its ability to deliver both immediate and lasting improvements, the thread lift continues to gain popularity as a preferred solution for age-defying beauty.

[kavinrathinam]

Everything You Need To Know About Gouri Injection

GOURI has an innovative liquid PCL (polycaprolactone) formula that spreads evenly across the entire face to work in harmony with our body's natural processes. It effectively smooths fine lines and wrinkles while restoring skin elasticity, resulting in rejuvenated skin that is clearly firmer and suppler.

Advantages Of GOURI

People in their 30s, 40s, and beyond who want to treat skin laxity or other signs of aging can benefit from GOURI. This collagen biostimulator works by naturally increasing the production of collagen, thereby effectively combating: Reduce Fine Lines and Wrinkles .

How is GOURI Carried Out?

Our aestheticians will evaluate your suitability during a comprehensive pre-treatment consultation prior to your GOURI treatment.

This customized skin assessment guarantees that the GOURI treatment is appropriate for your particular skin requirements. There are two different ways to administer GOURI: Using the 5-Point Injection Method, GOURI injection is injected into five bio-stimulatory points on each side of the face.

The Cannula Technique, which is preferred, is safer and less invasive and only requires two injection points on each side of the face. Our aesthetic doctors prefer to use the GOURI Cannula Technique because it minimizes side effects like swelling, bruising, and inflammation that are common with the 5-point Technique.

However, the GOURI Cannula Technique requires more precision and skill. A small cannula with a blunt tip is used in place of a standard needle in the Cannula Technique. A fine needle is used to create an entry point in the skin, which the cannula is inserted through to insert GOURI into your skin.

A layer of numbing cream will also be gently applied to your face prior to the treatment to ensure maximum comfort and minimize any potential discomfort.

[datastring]

Polycaprolactone Diol Market set to hit $354.5 million by 2035

Industry revenue for Polycaprolactone Diol is estimated to rise to $354.5 million by 2035 from $165.0 million of 2024. The revenue growth of market players is expected to average at 7.2% annually for the period 2024 to 2035.

Polycaprolactone Diol is critical across several key applications including polyester polyols production, biomedical sector, polyurethane production and cosmetics & skincare. The report unwinds growth & revenue expansion opportunities at Polycaprolactone Diol’s Grade Type, Applications, Manufacturing Process, Molecular Weight and End-Use Industry including industry revenue forecast.

Industry Leadership and Competitive Landscape

The Polycaprolactone Diol market is characterized by intense competition, with a number of leading players such as Perstorp Holding AB, BASF SE, Sigma-Aldrich Co. LLC, Daicel Corporation, Mitsubishi Chemical Corporation, Shenzhen Polymtek Biomaterial Co. Ltd, Corbion NV, Polysciences Inc, ., Evonik Industries AG, Esun, Invista and Ashland Global Holdings Inc.

Detailed Analysis - https://datastringconsulting.com/industry-analysis/polycaprolactone-diol-market-research-report

The Polycaprolactone Diol market is projected to expand substantially, driven by increasing demand in pharmaceutical sector and innovative applications in biomedical engineering. This growth is expected to be further supported by Industry trends like Environmental Sustainable Solutions in Coatings.

Moreover, the key opportunities, such as untapped potential in biomedical fields, technological advancements in polyurethane industry and striding into the asian markets, are anticipated to create revenue pockets in major demand hubs including U.S., Germany, China, Japan and South Korea.

Regional Shifts and Evolving Supply Chains

North America and Europe are the two most active and leading regions in the market. With challenges like high production cost and environmental concerns, Polycaprolactone Diol market’s supply chain from raw material procurement / polymer synthesis / processing & compounding to end-use industry is expected to evolve & expand further; and industry players will make strategic advancement in emerging markets including Brazil, India and South Africa for revenue diversification and TAM expansion.

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