#plasma clot

[biology-geology-beaches-india]

TSRNOSS. Page 191.

[dreams-and-honor]

[thecooleraveragejamm]

love that when i went to donate blood it clotted 3 minutes in, yet when I go to donate plasma it was perfectly fine

[literaryvein-reblogs]

Words to describe blood without saying crimson or blood?

Blood—the fluid that circulates in the heart, arteries, capillaries, and veins of a vertebrate animal carrying nourishment and oxygen to and bringing away waste products from all parts of the body

Arterial - relating to or being the bright red blood present in most arteries that has been oxygenated in lungs or gills

Body fluid - a fluid or fluid secretion (such as blood, lymph, saliva, semen, or urine) of the body

Carmine - a vivid red

Cerise - a moderate red

Claret - a dark purplish red

Clot - a coagulated mass produced by clotting of blood

Cruor - obsolete: the clotted portion of coagulated blood

Ensanguine - to make bloody; crimson

Geranium - a vivid or strong red

Gore - blood, especially: clotted blood

Hematic - of, relating to, or containing blood

Hematoid - resembling blood

Hemoglobin - an iron-containing respiratory pigment of vertebrate red blood cells that consists of a globin composed of four subunits each of which is linked to a heme molecule, that functions in oxygen transport to the tissues after conversion to oxygenated form in the gills or lungs, and that assists in carbon dioxide transport back to the gills or lungs after surrender of its oxygen

Hemoid - resembling blood

Ichor - a thin watery or blood-tinged discharge

Incarnadine - bloodred

Juices - the natural fluids of an animal body

Maroon - a dark red

Plasma - the fluid part of blood, lymph, or milk as distinguished from suspended material

Puce - a dark red

Ruddle - red ocher (i.e., a red earthy hematite used as a pigment)

Russet - a reddish brown

Sanguine - bloodred; consisting of or relating to blood

Scarlet - any of various bright reds

Vermilion - any of various red pigments

Word Lists ⚜ Blood ⚜ Exsanguination ⚜ On Blood ⚜ Writing Resources PDFs

[ratatouillewastakendammit]

HEAR ME OUT 😭 toga!reader who grew up with katsuki and izuku, she was always insecure about her quirk bc ppl told her liking gore was weird etc and ofc kats bullied her bc of that… until she grew older, realised how much her quirk can do, joined league of villains alongside dabi… maybe dabi takes a liking to her ^^ and he understands the need for revenge all too well… 🙂‍↔️ THATS ABOUT ALL I HAVE RN!

Wait this is so fun!! I usually try to keep the readers quirk undefined because I know some people want to insert their own but tbh I loveeee gory quirks and stuff

I'll Kill 'Em, You Hide the Body

Pairing: Dabi x Reader

Warnings: language, slightly suggestive, bullying, violence, blood (ofc), also it's been a while since I've written less dialogue heavy stuff so let me know if you have any critiques!

Word Count: 2.1k

Dabi had never been a fan of Toga.

The blonde was nothing short of psychotic, which he usually didn't mind by itself. Still, she possessed an undeniable creepiness about her that had him keeping as much as possible.

Seeing that she had wormed her way into his room to jab him for blood once may or may not have exemplified his dislike.

You on the other hand?

It was interesting how you and the blonde shared similar quirks, powers of seperate sides of the same coin with minor differences on how you used them.

It was even more interesting, however, with how much different the two of you actually were.

He remembered how you acted when you had first been introduced to the League, quiet and eyes glued to the floor, words slurred from the subtle way you tried to keep your mouth closed as you spoke. Still, your efforts seemed to be in vain, the soft whites of your sharpened canines becoming revealed the second you had joined them for a meal.

In all honesty, Dabi had thought it was dumb, how insecure you were of your quirk. He had seen mutant-quirk holders with features much more abhorrent than your barely noticeable fangs.

Spinner, the giant lizard man working along with you both was an easy example.

Shigaraki had accepted you, seemingly already knowledgeable of whatever powers you possessed when Giran had brought you to the hideout, leaving everyone else in the dark.

And while the others hadn't seemed to mind, accepting your soft spoken demeanor and mystery with open arms, Dabi wasn't exactly elated to have another weakling on the team.

How the hell would he be able to trust that you wouldn't fuck up if he didn't know what you could do?

So when Shigaraki had assigned you to his group for a mission, he had scoffed, grumbling about how you were just going to get yourself killed.

You, however, had been quite the surprise.

Drawing a small knife from your boot, you slid the blade over your palm, the metal leaving a thin line of scarlet behind. He watched as the liquid pooled over your fingers before rising in the air, leaving your skin clean and untouched.

He watched, cerulean eyes wide as he took in the horrific beauty you possessed.

Blood continued to slip from your cut, each drop falling upward to amalgamate into your dreadful creation, a vine of vermilion that trailed around a group of your opponents.

When a squeeze of your fist, the ruby liquid clotted together, wrapping around the men and pulling them together into a makeshift prison. The blood, now miraculously hardened, poked at their skin, pulling at their own plasma until it was also under your control.

You used your other hand, careful not to mix the substances, before forming the material into a scythe. If one listened hard enough, they could hear the edge of the blade slicing through the air, just as deadly and graceful as its wielder.

It was almost poetic, the way you cut through your foes with the innards of their comrades.

By the end of it, a gory havoc had exploded through the room, you, just as untouched and pristine as before all of it, standing in the middle of it.

Beckoning a finger forward, you drew your own blood back toward you, the fluid snaking back under your skin and gluing the cut back together.

Toga had been absolutely obsessed with you from that moment on, hanging off your shoulder and chatting your ear off whenever you would let her.

Surprisingly, you didn't exactly seem to mind, expression holding nothing was silent contentment, the way one may look at a younger sibling or apprentice.

Dabi, on the other hand, had only grown increasingly obsessed with figuring you out.

To say you grew up isolated was an understatement.

When your quirk had first been revealed, your parents had been happy, albeit a bit taken aback by the initial grimness of it, hopeful for the unwritten future of success you had waiting.

Blood bending had quite the potential, after all.

Similarly, your friends had been enamored by the creations of your ability, eyes wide in childish wonder as you made inanimate creatures float around the classroom, one of your favorite tricks.

Your life had started to end the first day you passed out in class.

It had been a small turtledove that time, red as rubies and small enough to fit in your hand. The avian organism flying over your head was the last thing you remembered before the world went black.

Filled with panic, your parents had rushed you to the nearest urgent care, voices laced with tension as they explained the situation, even as you woke up. The doctor had done numerous tests, each more exhausting than the last.

A few days passed, filled with fear and anticipation at each time you would faint without an explanation.

'Extremely low iron' was the first thing written on the report, letters big and angry. Still, those that followed were so much worse.

The notion of having to consume some form of blood, not only to sustain your quirk, but to keep you alive, left your family in shambles.

Each of your friends began to trickle away after the news as well, most scared by the rumor that you were secretly a vampire started by some blond a few grades below you. Bakugou was his name, that of which you had learned a few days later as the bullying continued.

Whispers lined the hallway as you walked past, each hushed syllable and scowl following you like a disease.

"She'll eat you if you let her too close."

"I heard she picks people off the streets and drains 'em."

The love for gore and scary movies you had definitely didn't help your case.

Regardless, back then, you would've easily watched some romantic comedy instead of your favorite slasher film, if only it could be done with friends by your side, giggling at the dreamy love interest and cheesy lines.

And despite your desperate yearning for companionship, maybe you would've been fine if it was left at plain isolation.

The worst of it started when Bakugou convinced some of his friends to break into your locker. They had taken your lunch box and dumped the contents out in the nearest trashcan before stuffing it back in, all of which you being completely oblivious to.

When you opened your lunchbox expecting the usual sandwich and bag of chips, your eyes had doubled in horror when they met the dead bird cradled within instead.

Home could have easily been a sanctuary for you, but it soon became just as depressing as school.

Thankfully, your doctor had been able to give you meager rations of the blood donations the local hospital received weekly. Still, you began to dread each time your parents went out to pick it up from the pharmacy.

They would hand you the bag to put in the freezer, fingers barely gripping the plastic like it was a dead animal.

As far as you knew, it very well could've been.

Their complaints ran through your ears constantly, vivid descriptions of the revolted looks the nurses would give him, followed by the scattered glances of pity they might get from other parents at the store.

Once, your mother had to excuse herself from the table, silently gagging at the ruby liquid in your cup. Soon it became a regular occurrence, both leaving in disgust until you were left to eat your meals alone, food cold and room silent.

A few years inched by before they pushed you away as well, lending you money for a small apartment on the other side of town, as far away from them as possible.

By the time you turned eighteen, they had cut you off completely, giving you just enough time for all that sadness and insecurity to meld into hate.

Joining the League was the first thing you did after moving out.

Surprisingly, it hadn't taken a long time at all for Dabi to take a liking to you, the quiet admiration stemming from his initial awe at your power, regardless of how much he didn't want to admit it.

Taunting you soon becomes his favorite activity. You were unexpectedly hard to fluster, but the way your eyes would flit to the ground in embarrassment made it deliciously worth it.

Regardless, the soft blood lust burning in your eyes whenever he would push your buttons too far had his pants tightening.

It was hard to decide which reaction he liked better.

Those were the reactions he was digging for tonight, arms crossed as he leaned on your door frame, smirking at the way you had mindlessly left the entryway to your room unlocked.

It was like you were practically begging him to come in.

He had learned of your past a few hours ago from Kurogiri, the dark mass of mist and fog easily digging out the information.

The knowledge had pissed him off, sure. In all honesty, he would've happily added another U.A. brat to his kill-list, especially once he recognized Bakugou's name, the idiot being in the same class as his darling little brother.

Still, Dabi had enough self respect to consult you first.

Or, at least, he had convinced himself it was 'consulting.' Whether or not it was more accurately 'annoying you until you did something worth the regret' was none of his concern.

And it was all the more motivation if he could worm his way into your good graces.

He definitely wouldn't mind letting you play damsel if it meant winning your affection in the end.

Maybe it was the mention of that blond twerps name, or maybe that of your parents, which had your fingers curling around your pencil, your line of sight glued to the paper in front of you.

"Get out. I'm working," you said without looking up.

"You know, fucking someone up would make you feel a lot better than writing in a diary." He walked over to where you were sitting, a smirk pulling on the corner of his lips. A hand slipped over your shoulder as he bent down, the warmth of his skin kissing your own as he whispered, "Or I know some other ways of relieving stress if you want help."

You scoffed, ignoring the heat building in your cheeks at the insinuation. "Are you always this annoying?"

"Only for you, doll."

Dabi was quite the flirt, and while you were quite masterful at hiding your own attraction to the man, each amorous comment had your defenses faltering.

"I just don't know how you can let that shit fly." His touch slid lower, hands snaking low enough to rest on your thighs, his breath tickling your ear. "If it was me, they would be six feet under right now."

"You really think I don't want to?" The heels of your chair slid across the wooden floor in an unpleasant screech, your pencil slamming against the desk as you stood and turned to face him. "I think about it all the fucking time! I just..." You swallowed. "There's no coming back from that... I don't know if I can."

Silence met your unwilling confession, clashing with the pit of embarrassment growing in your stomach. An attempt to hide from the scrutiny of his stare, you moved over to sit on your bed, resting your face in your hands as the stillness enveloped you.

"Then let me do it for you."

You looked up. "What?"

"I said," Dabi slowly crept over to you, gaze locked on your own. "Let me do it for you."

The way each syllable was enunciated with cruel ardor left you shivering, your skin prickling in goosebumps as the heat radiating off his body swept closer.

"I'll make sure to leave enough pieces behind to drain, if you want."

It was almost as if he could hear the blood thrumming through your veins, your quirk begging for the violent, venegeful release that you were being promised.

That annoyingly excitable muscle in his chest jumped at the way you looked at him, eyes dancing with a mixture of desire and ferocity.

Eventually, you gave your answer, quiet, but certain.

"Okay."

[macgyvermedical]

https://youtu.be/rUFRVEpvcA0?si=i38s_Z_rjpaifxRA.

Have you seen this video? It's from "The Fall" 03. 01 If you can't see this.

I want to ask that what do you think about this scene. Are medical teams realy like this in hospitals? Are they using right drugs in this scene? How they can know what is wrong with them. Also, can you explain about these drugs that they are using.

I could have sworn I'd done this before, but I couldn't find it, so here goes:

It's really accurate. The protocols are a little different in the US than in Northern Ireland, but everything really checks out. Hospitals do have teams dedicated to traumas (they might be specifically dedicated to trauma that day or just assigned to trauma that day along with their other rooms depending on how much trauma an emergency department typically gets).

They're doing a bunch of different things to determine what is wrong with him. For one, they know that he was shot twice because the paramedics (and likely someone at the scene) said so. Note that they check that is accurate by turning him over and seeing if there are any other holes in him.

There's a lot of blood involved so they can assume blood loss, even if there's no way to really quantify it.

They know his heart is working correctly because they are both hearing sounds 1 and 2 (the "lub" and "dub" sounds normally heard in a healthy heart) and he is on a heart monitor (which is recording the electrical activity in his heart). They also know his blood pressure is too low to measure (and then later they can only get the top number).

They do an ultrasound of his lungs to make sure there are no pneumothoracies. They notice he isn't breathing well likely by listening to and counting his breaths. They know the intubation went in the right place (the lungs instead of the esophagus) because they listen to both lungs and are getting CO2 out of the tube.

We don't see a whole lot else directly done in the trauma bay, but they do notice in surgery that he's bleeding from his spleen just by looking and feeling.

As for the drugs: They picked the drugs before he got there because they're all standard drugs to use a trauma or code situation. So they just have them all ready to go.

Saline: a mix of water and salt that helps increase blood volume due to dehydration or blood loss

Tranexemic Acid: A drug that helps blood clot

Ketamine: a dissociative anesthetic (used because unlike other anesthetics it typically doesn't cause problems with breathing)

Sux (suxamethonium): a paralytic drug used in intubations and general anesthesia

Phenylephrine and ephedrine: drugs that makes blood vessels smaller which increases blood pressure

Atropine: drug that increases heart rate during a code

Epi (epinephrine): a drug used both to make blood vessels smaller to increase blood pressure and to change a bad heart rhythm into a better one during a code

Glycopyrrolate: a drug used to dry up secretions before intubation

FFP (fresh frozen plasma): a blood product full of clotting factors which helps blood clot

Platelets: another blood product that contains another thing that helps blood clot

[oceanlipgloss]

MEAT SHOP

BEELZEBUB.

+ warnings: dark themes, erotic hues, graphic descriptions of horror and gore, inclusion of vore, strong language.

+ female mc, feminine pronouns.

No restaurant could ever dream of offering such buttery meat—never to be sold in any boucherie.

A precise percentage of fat. A measured amount of muscle. The perfect mix of flavours. Raw flesh softened into dough between his bloody teeth. Dead cells trickled down his smiling lips in strawberry streaks.

Her bones cracked like candy in his mouth, but she didn’t taste sweet.

A once-in-a-lifetime blend. Not flavoured like heaven. Paradise isn’t even a good thing, now is it?

Fuck, how long he had been waiting!

So close. He was so close! And yet, he was losing his fucking mind. Though God had created him a ravenous madman, sanity was still slipping through his feverish fingers and down his trembling hands. Like oil and grease.

There was no time to cut the cake. No time, no time, no time. None at all! None whatsoever. He had to rip a bite out of her.

No, no, no, no.

Hold it.

This is an only chance. Jackpot. A once-in-a-lifetime meal, remember? Even if it wasn’t a full course, lunch, breakfast, or so much as a snack.

He can never indulge in this grade of meat anymore.

Somewhere, in an insignificant corner of his scattering mind, the thought made him sad. What a shame it is for such exquisite food to never be enjoyed again.

Later, later. As for now!

Should he swallow her whole or rip flesh and bone apart first? Choke down meat or savour flavour? Lick blood or drink plasma?

In the end, he didn’t take the time to peel smooth skin back like he would have done with chocolate wrappers.

He couldn’t do it.

Not too long ago he had sent her an invitation into his bathtub. Locked up her hot body between his legs. With every kiss fabric melted off.

What a dirty human. He could smell the fucking arousal on her.

Dumb, clueless bitch.

Everything had to be just right. He did not want to miss the burst of even one particular cell. He hadn’t wanted to risk watering down the palate. So there were no flowers. There was no water. Nothing. Just pristine enamel. And him. It was empty.

His lips had kissed her shoulder softly.

And then his teeth had bitten down.

Gentle.

Hard.

Harder still.

He had torn away a piece of her.

What do humans say?

Oh, but of course.

‘Bon apetit!’

The tub overflowed with blood. Fetid burgundy burst under his weight and pooled onto the bathroom floor.

No difference between candied cherries and blood clots. Ligaments and tendons. Flecks of flesh and bits of bone. Broken fingers and curled toes. Cartilage that’s hard, but much softer than stone. He devoured them all, polished stains off glossy marble.

No crime scene or slaughterhouse could have compared.

His smile shone. He felt a little bit empty. Was it regret? Well, it’s too late! Such pleasure is worth every regret in the world. His guts ached in longing under his grimy nails. So good, though not yet full.

How he wanted more!

He adored the putrid pain, the harmonious flavour, the very gore.

So little remained of her...she couldn’t even be called a corpse.

No more. Not in any meat shop.

Once was not enough.

With trembling fingertips and a strange, twisted love, he stroked the girl’s skull.

Oh, you stupid little human, you.

If only there were more of you.

+tag: @/kanatashinkaifr does a gory jumpscare sound good to u? :P

+notes: Beel is very much thriller material. There is a cold-blooded, unstable part of him. A true gluttony incarnate—lusting for flesh, eating all there is, leaving nothing behind. No matter what resides in his heart and who the victim is, he's a devil and his sin continues to rule him. Even if he does manage to resist eating MC, his desire to devour her is a flame that still burns. Inspired by the in-game screenshots in this post.

This, my people, was a dark pleasure to write. Blood and meat, dear peeps ( ͡° ͜ʖ ͡°) I want to write more stuff like this in the future. I kid you not, I almost felt free for a minute. *Rubbing hands like a villain fly* hail horror, hail gore!

+ MASTERLIST

+ AO3 POST

©𝙤𝙘𝙚𝙖𝙣𝙡𝙞𝙥𝙜𝙡𝙤𝙨𝙨

[the-most-humble-blog]

𝘋𝘦𝘦𝘱 𝘏𝘪𝘷𝘦 𝘋𝘦𝘴𝘴𝘦𝘳𝘵 𝘋𝘦𝘭𝘪𝘨𝘩𝘵𝘴 – 𝘚𝘸𝘦𝘦𝘵 𝘏𝘰𝘳𝘳𝘰𝘳𝘴 𝘧𝘳𝘰𝘮 𝘛𝘩𝘦 𝘞𝘢𝘴𝘵𝘦𝘴!

(For the uninitiated, Warhammer 40K is set in a bleak, dystopian sci-fi future where humanity is crammed into massive hive cities, layered slums stretching miles into the sky. In the depths of these urban hellscapes, food is scarce, and the poor will eat anything—no matter how questionable. The following menu is from a hive-level eatery that specializes in desserts for those whose moral and digestive limits are flexible.)

☠ 𝙎𝙬𝙚𝙚𝙩 𝙍𝙚𝙜𝙧𝙚𝙩𝙨: 𝘼 𝙏𝙖𝙨𝙩𝙚 𝙊𝙛 𝙏𝙝𝙚 𝙋𝙞𝙩 ☠

1. Blood Pudding Pops – 6 Throne Gelt

🩸 "Like a plasma wound... but sweeter!" Nothing beats the crunch of frozen, clotted hemoviscera on a stick! This grim classic is made from recycled nutrient-rich blood collected from underhive meat pits (source unconfirmed, but best not to ask). Flash-frozen and dipped in a glossy sump-oil chocolate shell to lock in that just-slaughtered freshness. If yours still pulsates, congratulations—it’s extra fresh!

2. Rotberry Tarts – 5 Throne Gelt

🍓 "Fermented to perfection! (And legally not a biohazard.)" What’s that tang? Why, it’s our signature "wildly unregulated" fermentation process! We take overripe underhive berries—those resistant to most pesticides and mildly radioactive—and let them stew in their own juices until they develop that fizzy, borderline-alcoholic texture. Each tart is guaranteed to contain at least one hallucinogenic mold spore, so prepare for a spiritual experience or severe gastric distress—whichever comes first!

3. Bone Marrow Gelato – 7 Throne Gelt

🍦 "Creamy, dreamy, and questionably sourced!" Rich, indulgent, and packed with mystery marrow! Our gelato starts with a hearty extraction from bones we “acquire” from reliable vendors—whether they were volunteers or not is above our pay grade. Blended with vat-grown pseudo-milk and synthetic sugar, this treat has a delightfully gamey aftertaste and may come with "bonus memories" from its former owner! Some customers report experiencing strange, unfamiliar dreams after consuming—don’t worry, it’s just a side effect!

4. Nutrient Sludge Trifle – 8 Throne Gelt

🥄 "Corpse-starch meets luxury!" For those who wish to eat like the working-class masses, but fancier! We start with three layers of reconstituted corpse-starch (yes, the same protein-dense ration used to feed the Imperium’s least fortunate). Then, we drizzle it with a questionable "synthetic vanilla" syrup, pile on expired sump-milk custard, and top it off with candied cockroach wings for an extra crunch. The result? A deceptively sweet sludge that reminds you where you belong in the hive’s food chain.

5. Glowspore Éclair – 9 Throne Gelt

🌟 "It lights up! So will you!" A flaky, deep-fried chitin-crust pastry stuffed with bioengineered luminescent fungal cream that grows deep within the toxic runoff caverns. Not only does it glow in the dark (fun for kids!)—it’ll make you glow, too! Some lucky customers have reported seeing their veins light up through their skin. Others have found it difficult to sleep after eating due to the spores taking root in their bloodstream. Either way, it’s a treat to remember!

6. Hive Queen’s Egg Custard – 12 Throne Gelt

🐜 "The egg is... a surprise." Our creamiest custard, infused with nutrient-dense excretions from hive-born arthropods. The best part? Every serving comes with a mystery egg tucked inside. It could be a delightful, protein-rich yolk, or it could be a fertilized larva just waiting to hatch inside your gut! Either way, it’s the gift that keeps on giving.

7. Flayfruit Pudding – 10 Throne Gelt

🍮 "It peels back more than just your hunger!" This smooth, syrupy pudding is made from the ultra-rare Flayfruit, a mutated underhive plant known for its flesh-stripping enzymes. The flavor is a glorious mix of citrus, acid, and mild pain, and it burns just enough to let you know it’s working. Side effects include "accidental loss of soft tissue", and long-term consumers may experience spontaneous shedding of fingernails or lips. Pairs well with bone broth... if you still have bones left.

8. Ration Bar Tiramisu – 11 Throne Gelt

☕ "For the discerning scummer!" We start with old, expired Imperial Guard ration bars (the ones even they won’t eat) and soften them by soaking them in strong recaf mixed with sumpwater runoff. Then, we layer it with synthetic sump-milk foam and dust the top with a blend of carbon shavings and machine oil for that "authentic hive-flavor." The result? A tiramisu that makes you question your life choices.

9. Maggot Mousse – 6 Throne Gelt

🪱 "You didn't hear that squish." Whipped to perfection using the natural movement of hive maggots, this silky, protein-packed mousse is served chilled to slow their metabolism just enough to keep them from escaping before consumption. Be sure to chew carefully—some of them have been known to reactivate upon swallowing.

10. Emperor’s Mercy Pudding – 15 Throne Gelt

👑 "A dessert so good, it just might be your last!" The pinnacle of our menu: a thick, velvety pudding infused with underhive amasec and just a whisper of "unregulated chemical agents." Every batch is slightly different, meaning some experience a blissful, euphoric high, while others experience cardiac arrest within minutes. It’s the perfect dessert for those who wish to leave this world on a high note! No refunds, no liability.

🔹𝗗𝗜𝗦𝗖𝗢𝗨𝗡𝗧 𝗦𝗣𝗘𝗖𝗜𝗔𝗟🔹

🦠 "𝙁𝙚𝙖𝙨𝙩 𝙖𝙩 𝙔𝙤𝙪𝙧 𝙊𝙬𝙣 𝙍𝙞𝙨𝙠" 𝘽𝙪𝙛𝙛𝙚𝙩 – 30 Throne Gelt

Unlimited access to all menu items (if your digestive system survives the experience!)

Complimentary gut parasite removal (if the doc’s sober enough to operate!)

🎭 𝙏𝙝𝙚 𝙃𝙞𝙫𝙚 𝙈𝙤𝙩𝙩𝙤:

"Sweetness is fleeting. The horror is forever."

🍽 Bon appétit, scummers! 🍽

🔥 REBLOG If you want more!🔥

[covid-safer-hotties]

The Push for Off-Label Rx to Treat Long Covid

Also preserved in our archive

By Tinker Ready

Charlie McCone, a San Francisco marketing specialist, developed long COVID in 2020. Before he recovered, he developed another acute case of COVID, and in 2021 his long COVID worsened. He’s been sick with fatigue and shortness of breath since then, spending many hours of every day in bed.

Only one drug helped his shortness of breath, he said. But doctor after doctor refused to prescribe that drug, Plavix, approved by the US Food and Drug Administration (FDA) to prevent blood clots.

McCone began asking for it after doing his own research and learning it showed promise. When he finally found a doctor to authorize a prescription, McCone said, he began to breathe easier again.

McCone, now an advocate for long COVID sufferers as part of the Patient-Led Research Collaborative, a group of researchers and patients with long COVID, felt he had to take alternative steps. With no federally approved treatments for the millions of Americans who have experienced long COVID, some patients and doctors are turning to off-label drugs to manage the condition . But patients say it is not always easy to get a doctor to prescribe them. And in some cases, insurance will not cover the drugs, ruling them experimental.

In the case of Plavix, Stellenbosch University researchers in South Africa have published results of a blood plasma analysis that found patients with long COVID had microclots — and Plavix may help relieve them.

McCone and others are asking doctors to learn about and use off-label drugs that show evidence of helping long COVID symptoms. Among them: Low-dose naltrexone for fatigue Nicotine patches for fatigue Rapamycin for immune function Triptans for headaches Beta-blockers for postural orthostatic tachycardia syndrome, dizziness Paxlovid for viral persistence Plavix and other blood thinners for blood clots

“We don't believe any of these drugs are going to cure patients, but [using them off-label] can be the difference between a patient holding onto their job,” McCone said. “There could be a patient going from being stuck in a dark room to being able to socialize and enjoy their day. This can be difference of a parent being able to take care of their children.”

Not every doctor is going to be comfortable prescribing Plavix, McCone said. But there is some solid evidence to support the idea that low-risk drugs like it can bring long COVID patients a lot of relief, he said.

The Argument for More Aggressive Off-Label Prescribing Julia Moore Vogel, PhD, senior program director at the Scripps Research in La Jolla, California, was co-author on a paper published last month in Cell calling for a stronger push for long COVID treatments. The paper noted that “as patients await evidence-based care, many engage in self-experimentation on the edges of medical science.”

Moore Vogel and others say people don’t need to experiment. They can use safe, existing treatments if they know about them and a doctor agrees a prescription is warranted. She would like to see more professional medical groups do more continuing education on long COVID so doctors can learn about the best off-label options.

Groups like the American Academy of Physical Medicine and Rehabilitation have come up with a guideline on how to treat cardiac, respiratory, and other symptoms in patients with long COVID. But Moore Vogel thinks primary care doctors should take the lead.

“Part of what we're saying is a lot of it falls on the primary care physicians at this point because people are waiting so long to get into those subspecialties,” she said.

She would like to see recommendations for the primary care providers boiled down in simple terms about what is known about first-line, off-label therapies that have emerged.

Sterling Ransone, MD, a family physician in coastal Virginia, agrees that primary care specialists need to be educated on how to detect and treat long COVID.

He says he sees about one long COVID case a week, and sometimes his patients don’t know they have it. Patients will come in a month after symptoms, and he will ask them if they were sick and have tested for COVID.

“I literally had a patient tell me, ‘Is that still a thing?’” he said.

He suggests doctors add long COVID to the list of conditions they rule out when presented with confounding symptoms.

“What we need to do is make sure we always ask about the potential for long COVID with this myriad of symptoms,” Ransone said.

He prescribes off-label medication after doing research, if a patient asks for it, he said.

“If it's somebody I know well and they've got questions about something, I'll absolutely sit down and talk with them and tell them the research that I've done,” he said. “I mean, you know, from a physician standpoint, above all, do no harm, right?”

Once patients and doctors decide to try something, they need to get insurance approval. Some of the medicines are denied insurance coverage and are expensive, Ransone said.

“We have to go through prior authorization processes, and that's just another hurdle these folks unfortunately have to jump over,” he said.

One reason patient advocates say off-label medications are key is that clinical trials take too long, McCone said. Many trials of long COVID treatments are underway, but none have led to conclusive findings that have identified effective standardized treatments for the condition. As a result, the FDA has not approved any standard long COVID treatments in the same way treatments for other viral conditions and diseases have received approval and are widely used.

Patient Advocacy by Patients McCone is a patient representative to the National Institutes of Health’s RECOVER-TLC research program, which met this summer to launch a series of clinical trials. He said the organization is making progress, but results from the clinical trials aren’t expected until 2028 — a long time for patients with long COVID to wait.

He noted the upcoming trial of low-dose rapamycin, which researchers hope will address some of the immune or infection-related dysfunction that drives long COVID.

After McCone spent hours in bed for more than a year, he can now work at the computer for about 2 hours a day. His shortness of breath improved after he started taking Plavix.

“That's up from about 30 minutes. I can leave the house occasionally, once to twice a week, depending on the week,” he said.

McCone and others are calling for better continuing education for doctors about long COVID for doctors and more publicly available information to help patients know what drugs are already out there and might benefit them.

“Read the research, provide some low-risk treatment options to your patients, and let your patient decide,” he advised doctors. “I don't think this is asking you too much. This is a health crisis that's impacting every aspect of society.”

[dark-side-blog3]

You ever think about how the effects on the body that Purple Haze's virus has can lead to over a ton of body horror imagery in a Pannacotta Fugo route?

I do indeed.

++++++++++++++

While Fugo is very fearful of his stand, and he tries his best to keep it repressed, he does have moments even he can't get out of without its help. He tries to avoid those moments as much as possible, as the rabid apparition could kill its owner easily; Fugo is not immune to the virus he creates with his stand. Should his manifestation turn towards him in ire, Fugo needs to act fast to repress the spirit again, before buboes of phlegm swell his throat, cutting off air while splatters of blood and plasma erupt from a rash of blisters on his skin, the torn flesh melting and merging with itself as it gets covered in new blisters, each layer covering itself in torn shreds of skin from the previous layer that only emerged seconds before.

If Fugo is unlucky enough to be "saved" by a healer stand before he dies, after suppressing the stand, his skin will carry the scars, stretching and straining under the evergrowing disease under his skin. The disease never left, always mutating at an incredibly fast rate inside of himself.

In mere hours, his body is bloated, and cumbersome, unable to lift parts of himself off the ground and instead dragging them behind, tearing gently at the skin that gets raked over the concrete, oozing viscous strings of colgulated blood and dotted with white, shaving-foam consistency pus. His face is obscured under bulging, beating bulbs of flesh, with thin blue veins visibly trailing clots of blood through his body like threading a bead on a string slowly, and with great difficulty as his cancerous arteries lead back into each other, enough times that some of his- at one time- extremities turn a sickly necrotic purple and black.

You'd barely recognize the shambling mound of flesh as Fugo if it weren't for the fact you'd seen him get attacked by his stand after trying to deter it from you.

And if it weren't for the fact you'd seen birds and dogs die from the same disease as he got close to them, you'd be tempted to offer comfort to the former man. Despite lasting this long with the disease unable to kill him, it seems he's still a carrier for the original death Purple Haze entails.

You'd been running from him for hours now-- though he's not particularly fast, his persistence despite what must be agony is what keeps you moving. Resting in any place for too long will only let him close the distance. The blisters and swelling have no doubt gotten to his brain, killing whatever could have been left in him, causing him to act irrationally and chase you in the open, undeterred by pain, threats, bribes, empty promises, or gunfire. He's not Fugo anymore, unable to call upon his Stand, or even understand his old name (and you've tried to use it to escape before, attempting bargaining with the creature). He's just... A monster. Determined to follow you wherever you go, until it can absorb you with bubbling stomach acid, or infect and fuse with your melted, blistering, corpse.

[the-dye-stained-socialite]

i was thinking about elias and their Scary Powers earlier and i actually came up with a neat little connection about why Elias has problems stopping their heart-reading

their power is based on this text^ but with some additions and dofferences. specifically, the power is made innate, not from a stave

so! the red court is linked to blood! elias, notably, has hemophilia! they might have been a carrier on the Surface with only a small degree of the symptoms, but mixing their blood with the waters of the Persephone now means they have full-blown hemophilia, meaning their blood doesn't clot (plasma problems!).

so i think they can't stop their heart-reading because it works like blood, and their blood doesn't clot, thus this won't stop naturally until it has reached the end

or until they get hit with the Discordance. Ice was used historically to help stop bleeding with hemophilia, and getting hit by Ice Magic would put an end to the bleeding

[literaryvein-reblogs]

Writing Notes: The Human Body

A Quick & Simplified Guide: Blood

What does the Blood do?

Carries oxygen to our cells

Transports hormones (messenger molecules in the body) & other vital chemicals

Carries away waste

Transports immune system agents that track down and kill dangerous invaders

Makes sure oxygen gets to the parts of the body that need it most (such as your leg muscles while you’re running)

Helps to regulate your body temperature, so you don’t get too cold or too hot

Haemoglobin

A hero protein with a dark desire for something extremely dangerous: carbon monoxide.

If carbon monoxide is around, haemoglobin will pack it in, like passengers jammed together on a rush-hour train, while leaving the oxygen standing on the platform.

This is why carbon monoxide kills people – because they don’t get enough oxygen travelling around their body.

4 Components of Blood

Red blood cells

44% of your blood

One teaspoon of human blood contains about 25 billion red blood cells.

They all have one job: to deliver oxygen.

They ship it around the body using haemoglobin.

Each red blood cell lives for about four months.

In that time, it will be shot around your body about 150,000 times, logging about 100 miles of travel before it’s too battered to go on.

Mostly because of 100 billion dead red blood cells that you have to get rid of every day, feces is brown.

White blood cells

Less than 1% of your blood

These cells are a vital part of your immune system.

They are critical for fighting off infections.

Platelets

Less than 1% of your blood

One of the main jobs of platelets is to manage blood clotting.

Let’s say you accidentally graze your elbow on a wall. You might think: Ouch, but it’s not so bad. Your platelets will not be so relaxed. Millions will instantly cluster round the wound (well, scratch). At the same time, a protein in your blood will transform into a tougher protein called fibrin. The platelets and the fibrin get together to form a plug, which seals up the wound and becomes a scab. This (a) stops you leaking, and (b) is virtually impossible not to pick (but do try not to).

Plasma

A bit over 50% of your blood

Plasma is 90% water, but it also contains some vital things, including proteins that help blood to clot.

Source ⚜ More: Writing Notes & References Blood ⚜ Blood Alcohol Level ⚜ Exsanguination ⚜ Injuries ⚜ Wounds

[kvotheunkvothe]

today not ONLY had hemoglobin sufficient to donate, but could do POWER RED!! (that's where they take about 2x the red blood cells but give back all the plasma and platelets. super cold going back in). not had HGB good enough for that in years, so I'm super happy to switch over to that! partly because it's useful in hospitals, but partly also cuz the one prior time I felt back to normal way faster with a lot of fluids returned (even though, again, I must stress it comes back in COLD).

the place was packed and they also were SLOWLY getting through people. and just while I was there, one person needed a proloooonged lie down, and another had to take a break in the middle because I guess she felt faint? bizarre. anyway, there's just the one power red machine, and luckily the guy before me was about done when I'm coming in. the lady managing the machine for me seemed a bit flustered and uncertain of how to run it, so there was kind of a lot of people gathering around to discuss error codes and things. afterwards she took out my needle and yelped when there was a spurt of blood, yelling "I NEED HELP" like twice because no one paid attention the first time (she'd called it a few times by then because all of her questions about the machine). while I'm just holding my arm up and putting pressure going "it's okay, it's just blood," while they get it off the bed... aaand some of the equipment... aaaaand the floor... okay it was kind of a BIG blood spurt. the lady even flinched when she checked to see if I was clotting, which I was, so it was mostly funny

[darkeagleruins]

Americans Are Being Poisoned

“Suppliers have been caught using a special product known as meat glue to stick together scraps of meat”

Meat glue, also known as transglutaminase, is legal in all 50 states.

It is used in about eight million pounds of meat every year in America

“The hidden ingredient that’s making you sick”

“I've just got some, fine diced beef and my special enzyme. I'm just gonna mix it up a bit.

Why have we got the masks on?

This is dangerous. See that? Don't breathe that in.

This powder is transglutanamase enzyme, otherwise known as meat glue. Meat glues come in a number of forms, some produced by cultivating bacteria, the others, the primary ingredient comes from the blood plasma of pigs and cattle, specifically the coagulant which causes blood to clot. Ours uncooked is easy to spot the difference, but cooked is another story. Okay.

(SEE VIDEO FOR IMAGES)

Meat glue one is on the right, and the real McCoy is on the left.

And it's not just beef. Pork, lamb, fish, and chicken are all stuck back together using this glue.

If this food is sold or represented as a solid piece of steak and you cook it rare, you're really leaving yourself open, um, to get food poisoning. And chances are, unless you're a vegetarian, you're eating it on a regular basis.”

[vague-humanoid]

Just a few days before our interview, Jill’s (Ed: not her real name) immunologist sent her to the hospital to rule out pulmonary embolism, which happens when a blood clot gets stuck in an artery of the lung. In Jill’s case it would be a Long COVID symptom amongst many others she had been battling over the last year: including swelling around the tissue of her heart, memory deficits, sudden heart-rate surges, fatigue and abnormal kidney test results.

By that point, she’d had COVID four times, despite taking stringent precautions. She was born with a primary immune deficiency. And, without a fully functioning immune system she needs weekly injections of human immunoglobulins from plasma donations. A very small viral load can make her sick and she’s at a much higher risk of severe outcomes from COVID than most people.

“Every time I catch it, it adds new layers to my disabilities,” she says. “COVID is slowly killing me.” Her haematologist believes the past COVID infections have further damaged her immune system. She is looking at a possible lupus diagnosis.

Her voice is raspy and soft over the phone. She pauses when I ask how she is doing.

“Well, I got COVID,” she says. “Again.”

At the hospital appointment several nurses were not wearing their masks properly, and one kept pulling it down to talk with Jill, who had to remove hers to get her lungs checked. As someone who is very isolated with her family — everyone works and goes to school from home — Jill believes that the appointment led to her most recent infection.

She’s always been careful with her health but in the past, she worked in the school system. By 2020 she moved to a remote position and at that time still had many options for safely connecting with those around her and she could attend health-care appointments without concern. About a year ago, nearly all restrictions were lifted in Alberta and that’s when she got her first COVID infection.

Three years in, nearly everyone she knows has moved on including — most bafflingly to her — many of the medical professionals she sees. But, Jill says, moving on is not a privilege afforded to people like her.

Recently, PCR testing became inaccessible to health-care providers, who, in the past, were able to test regularly. And while Alberta Health Services (AHS) still requires masks, any health-care settings outside AHS can make their own rules. So, once masking was no longer mandated in public settings, many dropped requirements — this includes many of the specialists seeing immunocompromised people, including those Jill now sees due to Long COVID.

“The variants have been left to run rampant and I have really become more and more scared,” she says.

“Governments are saying: Oh we can re-open because we have all these tools. But they are not available to the immunocompromised population. So, the monoclonal antibodies are no longer effective against the current variants. Because the variants are so immune-based, the vaccines were never particularly effective for immunocompromised people because of the nature of our immune systems.”

As well, Jill says that there are many contraindicated drugs that cannot be taken with Paxlovid, the drug which is used to treat COVID patients in specific circumstances. According to Health Canada, Paxlovid “is used in adults to treat mild to moderate coronavirus disease 2019 (COVID-19) in patients who have a positive result from a severe acute respiratory syndrome Coronavirus 2 viral test and who have a high risk of getting severe COVID-19, including hospitalization or death.”

She still takes the vaccines with hopes they will help, and while she believes Paxlovid is saving her life with this current infection, she says it is not a guarantee against more Long COVID symptoms. And, for the infection prior to the current one, the drug was not available due to a kidney infection caused by the virus.

“I have to access my medication, my health care. And by people not masking around me, I have no way to protect myself,” she says. “If you don’t want to wear masks as a society then you are going to leave the immunocompromised people behind.” And she says many high risk people are not able to work from home, or have their kids in online classes or maybe struggle to afford masks or air purifiers — many social and financial issues make individual protections far more challenging or impossible. She is currently in a court battle with her ex.

“He wants increased access, in-person school and group extracurricular activities. All things that put me at higher risk of infection,” says Jill.

Recently, she went to her cardiologist to find that no patients or staff were masking.

“I really realize now I have to be my own advocate,” she says.

She has to constantly think ahead. So, she now calls beforehand to see if the appointment can be done remotely or if the staff can mask. She’s also decided to start carrying around a laminated sheet that explains her medical condition as it is often something she needs to repeat at each appointment or in the emergency room. 

Like many others, she’s found ways to navigate her way around a harrowing array of risks. And yet, even with all these precautions, she can not control the actions of others which can directly affect her health.

Holly (Ed: not her real name), is retired and lives in a small community just outside Edmonton. She’s currently thinking about her next visit to her doctor, who hasn’t been taking precautions from the beginning.

“It’s exhausting always trying to get around how there is no protection for us anymore,” she says. “I’m thinking why am I made to feel crazy when my own doctor won’t wear a mask? Won’t acknowledge that it’s airborne?”

But the worst part, she claims, was that he minimized the effects of COVID, saying it was rarely an issue and only affects a certain demographic. Holly does not believe that is true, but regardless it is of little comfort when her husband, who’s in his 70s, has chronic health complications.

“I think patients are rightfully concerned, particularly when they go in for health care,” says physician Neeja Bakshi. “I think the medical community should be doing whatever we can to protect those who are coming in.”

It’s true, she says, that hospitals are no longer overwhelmed, and fewer people are dying; there is less of an acute emergency. But COVID is still circulating, people are still dying, and Long COVID (aka post COVID-19 condition) should be on everyone’s radar.

Recently, the World Health Organization announced an end to the global health emergency. But it also said earlier that “one in 10 infections result in post COVID-19 condition suggesting that hundreds of millions of people will need longer term care.”

COVID can cause organ damage — particularly affecting the heart, kidneys, skin. Plus, there’s risk of brain and immune damage, along with increased risks for cancer and autoimmune disease.

And, while no one knows yet how long that damage could persist, a study published in the Journal of the Royal Society of Medicine says 59 per cent of Long COVID patients had organ damage a year later.

In 2022, Bakshi started a Long COVID clinic at her health facility Park Integrative Health, treating patients from across Canada. Every week she completes upwards of 20 disability forms for people who need to take time off work due to the debilitating effects of Long COVID.

While certain health complications make Long COVID more likely, anyone can be affected regardless of the severity of their infection or the state of their health. The indiscriminate nature of COVID is one of the things that’s been most shocking to Bakshi. She’s treated a number of elite athletes who went from performing at a professional level to struggling to have enough energy to brush their teeth.

Many patients struggle with stigma not just from medical professionals but from family, friends and employers. It’s an invisible illness, says Bakshi, so patients may look fine and are often misdiagnosed as something psychosomatic.

“I’m immersed in the world. But I don’t feel like you can deny it exists. And I think it’s a bit of ignorance on the medical community’s part if they say they don’t know anything about Long COVID. There are very specific disease patterns and symptoms,” says Bakshi.

There is also a lack of support. The most proven management strategy for Long COVID or even any COVID infection is recovery and rest, says Bakshi. But that’s not possible for many people. Initially, in 2020, there was forced rest through quarantine periods, but that time off has become shorter, as employers don’t have to pay for employees to be off at all.

“We are not a society that is built on support. We’ve already set ourselves up to fail from a recovery perspective,” says Bakshi.

Jill has found validation in Bakshi’s clinic as one of her patients. But that experience stands out amongst a sea of specialists who have given up on precautions.

“Instead of recommending upgraded masks, air cleaners and UV, or working from home, immunologists that manage my condition recommend wearing a mask if you want and enjoying your life—as short as that may be. I am not sure if this is complacency, or giving up… Either way, education and change need to happen or far too many valuable lives will be lost and disabled unnecessarily,” says Jill.

Savvy AF.  Blunt AF.  Edmonton AF.