#pathology test for cancer

[pinkybuttons]

mutuals. friends and relations. can everyone cast a 10,000 explosion attack on genetic health queensland pls. thank you.

[vaidyaslaboratory]

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[agilusdiagnosticsseo]

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[evildilf2]

Hey guys, my friend Ayiko recently got diagnosed with colon cancer and needs help paying for his cancer treatments.

“*grey freeze frame* i’m sure you’re wondering how i got here—and for those of you who don’t know, i’m Ayiko, a 22 year old queer artist and musician. I’ve always been a creative, from theatre to a film major. My dream is to keep creating, to keep telling stories, to keep sharing my art with the world and with your help i’ll be able to continue with what i love, with my passions. On the night of February the 6th, what was thought to be a routine doctor visit for severe stomach pain turned into an in-patient hospital stay. A CT-Scan revealed the source of the pain was from a rare telescoping and entanglement of the intestines, known as Intussusception. After a successful colonoscopy relieved the pain, it also revealed a lump that was removed during the procedure. Further testing by the pathology department discovered that not only was the lump cancerous but there were additional tumors that were inaccessible without open surgery. The cancer had grown into 5cm tumors and had spread to some lymph nodes. On February the 17th i went under the knife(or in this case a laser) for a robotic colectomy to remove the remaining cancer. There was very little risk in it spreading and it was one of the least aggressive cancer of its type(Neuroendocrine Tumor of the Gastrointestinal Tract). After the surgery, i will be unable to lift more than 10 lbs or walk for long periods of time, which has left me unemployed. Now in post-recovery, i gently ask the community to rally behind my family and i as we face the financial burdens of hospital bills. As a first generation immigrant i am also aware of the family back home that my parents have to look after too(in fact my father is going to visit Uganda in less than a week). That’s why we would greatly appreciate donations of any amount, as i continue my recovery and face the possibility of chemotherapy. Just sharing the link can go a long way. Thanks for reading!” -Ayiko @pretty-roach

Currently donations are at 1.2k out of a 20k goal- any & all help is appreciated, please reblog to circulate.

[brf-rumortrackinganon]

Rumortracking Anon, here’s my take vis a vis Hazno(fill-in-the-blank) on the broad timeline of BP’s announcement that KCIII has cancer. We were told that cancer was discovered during KCIII’s benign prostate surgery, and that it was “in a different part” of his body. It’s quite common for undiagnosed malignancies to be discovered in this way (a good thing). It could be in another part of the genitourinary system (eg, the bladder), was detected via scope through that organ system, and biopsied. It could be hematological and have been detected via bloodwork. We just don’t know. However, as with all suspected cancers, it would have to be confirmed by pathology testing, which usually takes 7-10 days, depending on which tests are required. 

IMHO, KCIII and Camilla were informed of the potential cancer immediately after the prostate surgery was completed, and then William and Anne (at least) were informed soon thereafter. They all still had to wait for over a week for pathological confirmation, during which time they kept it 100% private. Once they had confirmation, and a treatment plan/schedule was finalized, only then did BP make an official public announcement - necessary because KCIII would be immunocompromised from treatment (whether chemotherapy, radiation, or immunotherapy) and would have to cancel public appearances.

They waited to tell H in California until just a few minutes before BP released the public announcement. That way, he (ie, Meghan) had zero time to leak the news to Scooby Doo the press. In other words, H found out 7-10 days AFTER KCIII, Camilla, William, and Anne (and others as well) knew. Even on the very slight chance that H/MM wouldn’t have leaked (as if lol), H still would’ve hopped on a plane to London pronto, alerting the press anyway that something was amiss.

Harry truly has been PNG’d by the BRF. He’s out of the royal loop, totally ostracized. Never again will they be able to trust him - with anything - and he did it completely to himself. No family secrets, no intimate family holidays, no impromptu meetings with KCIII or William, they don’t even trust him to stay overnight at a royal residence anymore…“go to a hotel, Harold.” Where’s Shakespeare when one needs him? Imagine the play (a history? a tragedy? a comedy? all three?) he could write of this royal saga! It would have to be in 3-15 parts, though.

***

All of this tracks and makes sense to me. I do agree that Harry was called at the last possible moment. Another anon and I were discussing earlier tonight the speculation that Meghan was leaking to Scobie/other reporters about the Queen’s illness and her death before the family was ready, and the family was later made fully aware. So in that case, it is completely believable that the BRF waited until just before the news dropped to avoid the same scenario. Could you imagine the panic that would have been if someone other than the official BP spokesperson announced the King had cancer? I mean, there was plenty of panic when it was under BP’s control.

And you’ve just reminded me of something - Charles ended up stayiing an extra day at the hospital. I think he was originally meant to leave Saturday/Sunday, but instead he left on Monday. At the time, I had thought Charles delayed his departure so as to distract the gathered media so Kate could leave unnoticed. Now, however, I wonder if the extra day was so his doctors and care team could do some additional testing.

And really, who needs Shakespeare when South Park is available? 🤣🤣

[sweetlikehoneystingslikeabee]

If it's possible to request all the riddlers I was wondering if we could have their reaction to their s/o breast cancer scare? (Totally not me projecting)

Thanks of you do this!

❤️ anon

"Breast Cancer scare" Riddler party x Reader

First of all, I want to thank you for having patience with me on an ask that's much more personal. Second, I'm hoping by you saying scare that everything was all good? I had to get extra scans a few years back on something sketchy and I was PETRIFIED the entire time waiting for results.

TW: Cancer

Gotham

He's not going to freak out. Nope! Absolutely not. Freaking out is a thing that is not helpful to a situation like this and you don't need ANY additional stress. You notice he's stimming a lot more the past few days... His leg won't stop shaking and bouncing when he sits. He knows what cancer does to the body, he's seen it first hand. How it ravages.

This can lead to a potentially morbid road where he's trying to tell you as much about it as possible. Because if he informs you, it won't be as scary because you'll be expecting it. You'll both be prepared. The way to get this on a better route for the both of you is to have him explain the tissue scans and testing. He can tell you the entire pathology process of it. He holds your hand going through it and it seems to help.

He's going to be reviewing the scans and any results himself after they give you the medical okay. This is in fact to the annoyance of all your doctors, thank you for asking. Edward rationalizes it- No, he's not an expert but he's probably smarter than all of them put together and he knows what to look for. He just... He just wants to see for himself that there's nothing abnormal.

60s

Uncharacteristically quiet. There's no wit or jokes to be made about something like this. Mentally he runs into all the possibilities of results, treatment, how he's going to help you pay for anything you might need. What the future might hold for the two of you. For an instant, he thinks about a world without you and it's enough to feel his heart breaking.

There's these instances where you can see his normally well-kept self slipping. His hair not brushed into place. His clothing is messy and not tucked in. Holding your hand too tightly as you're called in by the doctor or the technician. Pacing for your return. Then you're back and the waiting begins. The worst part.

Then everything is okay. Results came back negative and you're completely fine. A nervous laugh. He makes a joke about your "marvelous, magnificent mammaries" being safe and sound. His insane cackle fills the air. Then he falters for a moment. Sways as though he's faint. You can see the tension physically break over his shoulders. You're alright. That's all that matters.

Capullo

That's a joke... right? It's not funny. Why would you tell him that? You know how serious that is? How is he supposed to focus on ANYTHING now? Everything is getting put on hold until you've been through testing and given the okay. Because OBVIOUSLY you're going to be okay.

Some people remark him as a vain man- which is true. There's an instance when it seems as though it could be positive for cancer. Additional testing or delays, what have you. He gets down to his knees and hugs your legs. Calmly, he tells you he's not leaving, no matter what. He'll love you if your hair all falls out, if your breasts have to be removed. None of that will change how he feels about you. He needs you to hear him say it.

As the negative results come in... He's smoothing back his hair and speaking too quickly. Good. It's good, you know? He quotes Princess Bride, “There's a shortage of perfect breasts in this world. It would be a pity to damage yours.” Ignore the way his hands are shaking HE'S FINE.

BTAS

What do you need? It's the first thing that falls from his mouth. What can he give you or do for you that will help in this time? Rationally speaking, he's not only trying to help you, he's trying to keep himself busy doing things for you as to not focus on the possibilities. He'll clean for you and cook for you and shop for you- Just tell him, sweetheart, and he's going to do it for you.

He will drop you off for any and all appointments but he won't stay by himself waiting. He can't. He can't stay in that place and imagine- Imagine the results. Think about what's happening to you in there even though it's standard procedures. He'll confirm about how long everything will take and be back just before you're out. He brought you lunch, your favorite :)

He finally looks tired when you're given a clean bill of health. He's been running himself ragged for this. It's what he wanted to do, but that doesn't make it less exhausting. He confirms that you're okay and then goes to sleep for almost ten hours straight.

Telltale games

Potentially the most level-headed about it. On the surface. He blinks when you tell him. He rattles off statistics about how much more likely it is you'll receive a benign diagnosis. It can come off cold but it's all an emotional defense mechanism for him.

This doesn't stop him from attending any and all appointments you're going to need for confirmation. They aren't letting him in the room, of course, but he doesn't leave the imaging center. He doesn't leave the doctors office. He sits there with a book when they tell him you'll be a while. He... can't leave you alone with this. He needs to know how it was when you come out- if you're okay.

When everything is alright he'll act as if he was never worried in the first place. See? He told you. Were you worried? Don't worry, that's what he's good at is keeping YOU grounded. It's not like if something happened to you he'd burn the world down or anything.

Arkham games

He attempts to act as though he's not freaking out about it. These things happen. No matter what, the two of you will figure it out. You'll get the results and... Whatever happens happens. Nothing can be changed now. That's just logical.

Later on, maybe even months later, you'll find plans he had developed that involved so much abduction of the top cancer researchers in the world into one laboratory space. Their entire lives, potential blackmail he could use, bribery- All of it was for you. He spiraled himself into the worst possible scenario and what he was going to have to do to make you better.

When you tell him officially that everything is in the clear, he asks if you're sure. You see his shoulders relax and he actually gets up to hug you. No smart ass response. No quips. Just a sigh.

Batman 2022/Nashton

When you tell him about the possibility, he's going through several phases of upset at one time. Denial, then anger, then depression- At some point he will lock himself into a room to have a full blown panic attack. This isn't on you. He does WANT to know something this important. It's just his emotional coping mechanisms are still horrendous and he doesn't know how to handle this. How to handle the mere idea he could lose you and there's nothing he can do.

If there is a service where you have to refresh to see results after testing, he's going to be refreshing every ten minutes on the side. If the results are even a day later than they said, he's calling. You, his lover, NEEDS to know! HE needs to know! Right now!

He does tear up when he realizes you're going to be okay. For once, it's happy tears, he's just so relieved. When you go to bed that night, he's going to big spoon you and stick like velcro.

BTAA

No, no! That's not- Listen, sweetheart, you can't get sick like that. You just can't. Because that would mean you're not okay. And if you're not okay, he's not okay! Okay? So let's just talk about this. From the top, tell him why your doctors have it in their numbskulls that you could have cancer. He's pacing back and forth. Okay. You'll get the tests. And then... he'll figure this out. You point out he's not the doctor and he waves his hand.

Gets very testy with the office when they get your appointments mixed up. He is on the phone and he is going to make someone regret their mistakes. Don't they know how important this is? How vital it is that this process goes as smoothly as possible so you can get what it is you need? Does he need to come down there and talk to a supervisor? Because he fucking will and- Yes, babe, he's fine but they can't just treat you like this!

Bundle of anxiety until the results come back. There's so much to unpack here and most of it boils down to cancer being an incredible unknown factor he has no control over. For him, that's terrifying. What if he lost you? Even after he knows everything is okay, please just let him hold you.

[houseofbrat]

Oh, look, a medical doctor in the US questioning the party line regarding KP’s timeline regarding Kate's health updates!

And the Daily Mail oh so conveniently lobbed his comments in with Christopher Bouzy of all people.

Jonathan Reiner, a medical doctor with internal medicine and cardiology certifications, who teaches at George Washington University is no slouch and no dummy. He also has no skin in the game regarding the British royal family and any of their fandoms!

And what was it that Rebecca quoted him as saying?

He was among conspiracy theorists who spread a CNN clip, which has now been viewed millions of times, in which a doctor claimed that Kate's statement did not make 'medical sense'. Asked how cancer could be found after surgery, Jonathan Reiner said: 'With all respect to the Royal Family, that kind of press release doesn't make a lot of medical sense.' The professor of medicine at George Washington University said such operations are preceded by extensive CAT scans and MRIs, adding it was 'very likely' the surgical team knew of the cancer prior to operating.

Ah, yes, only "conspiracy theorists" would listen to a doctor saying that Kensington Palace's timeline makes no sense. Because apparently in the world according to KP, Kate had "planned abdominal surgery" on 16 January 2024, but the doctors would not know about non-cancerous fistulas or bowel obstructions before they cut her open? Kate had "planned abdominal surgery" and all the normal planning such as CT scan or MRIs were never completed in the planning stages??

According to Rebecca's article, we should ALL dismiss the critiques of KP/Kate's timeline because there is no way they would have suspected cancer until weeks later.

That's what Kensington Palace apparently wants everyone to think.

Did you miss CNN's segment with Jonathan Reiner, MD? Do you want to see it yourself? Well you can, courtesy of the TV archive.

Part A

Part B

Part C

Part D ~ this is the part that gets quoted in Rebecca's piece

Part E

Part F

Part G

This is the part of Kate's statement that Dr. Reiner is critiquing:

In January, I underwent major abdominal surgery in London and at the time, it was thought that my condition was non-cancerous. The surgery was successful. However, tests after the operation found cancer had been present. My medical team therefore advised that I should undergo a course of preventative chemotherapy and I am now in the early stages of that treatment. “This of course came as a huge shock, and William and I have been doing everything we can to process and manage this privately for the sake of our young family.

Doctors would have briefed Kate about the possibility of any cancer prior to any "planned abdominal surgery." Saying it was "a huge shock" to a cardiologist--who says that "doesn't make a lot of medical sense"--as Kate's statement reads to other medical doctors as if proper planning wasn't done. Kate's medical team would have informed her about the possibility of finding cancer not just before anything was sent to the pathology lab but before the surgery even took place. So...is it really that Kate was not informed by her medical team about this possibility or was Kate's surgery not planned?

KP keeps being real cagey about that surgery, and it doesn't make them look good. It's already known amongst the media that Kate has known about this cancer diagnosis since January, even though they didn't tell the public about it. Kate is using the excuse that she could only tell the public now due to the alleged possibility of mean kids at Lambrook, which I sincerely doubt because the world heard about their grandfather having cancer just a few weeks ago and I have yet to see a story with accusations about mean kids at Lambrook bullying George, Charlotte, and Louis over this.

Someone ain't being truthful about this situation, and I don't think it's Jonathan Reiner.

[halizumab]

Is your name a combination of Hal (infinite jest + Zum (burzum) + mAb (monoclonal antibody)

i’ve actually never read infinite jest! i work in pathology/laboratory medicine and i’ve always loved monoclonal antibodies; immunotherapy is super cool but the naming convention for them is comically absurd (cue commercial for asgfhsskfjsjjmumab that Cures your Everything). part of my job when evaluating cancer is to do immunohistochemical testing on the tissue to see if the person would respond well to targeted therapy with mAbs (pembrolizumab, trastuzumab, etc) & relay that info to their doctors so they can get the treatment they need.

so i was like damn i need a url that’s completely nonsensical and impossible to pronounce. “hali” is an abbreviation of my given name so it works well as a nickname on tumblr and discord and such :)

[atlas-of-a-human-soul]

Hi, I just wanted to ask how you and your dad are doing? Hope all is well and you are both getting better.

Dad is out of the hospital, but we are still waiting for the pathology report to see if it's indeed a 2nd cancer or not. I'm scheduled for surgery in early January, so we will see. During preop tests I managed to get an asthma diagnosis now too, and they require I get blood transfusions around the time of the surgery due to severe anemia, so 😅. I'm working for a little while longer, just to take care of some last minute stuff with patients, since I'm essentially abandoning them for a month, but after that I'm off most of January for the surgery and recovery period.

How did you spend the holidays? What are your plans for new years? Anything exciting?

Also, have you been following the Luigi Mangione case? It's giving my brain an itch I can't quite scratch and as many others I am invested, even halfway across the world 🤣 if you are, let me know your thoughts! Same goes to anyone else willing to discuss the alleged charges he's been slapped with!

[myhealingera]

Two weeks after this photo was taken, I received a phone call that nobody ever wants to receive.

I was dealing with a slew of health issues: an inability to lose weight, hair loss, swollen lymph nodes, fatigue so intense that getting out of bed felt like a miracle, and severe brain fog. My joints were in so much pain that I found myself using a heating pad for most of the day.

I consulted my aunt, who is a pediatrician, and she reviewed my recent blood work. She observed that my TSH levels were consistently borderline high, often surpassing the normal threshold. Encouraged by her insight, I visited my OBGYN and shared my symptoms. She ordered hormone testing and referred me to a rheumatologist, given that lupus runs in my family. The results indicated elevated TSH, DHEA, and C-reactive protein levels.

I then saw a remarkable rheumatologist who conducted over 120 tests. All came back normal except for my thyroid antibodies, and I was diagnosed with arthritis in my hands. Around this time, my neck began to swell, feeling as though something was stuck in my throat. My primary care physician scheduled an ultrasound, which revealed swelling in my neck and a lymph node, and identified a nodule or "ectopic" tissue.

Returning to my primary care doctor, I was told my lab results were normal and advised to follow up in a year, despite continuing to experience swollen lymph nodes and being told that the neck nodule was unrelated to the swelling. At this point had been to urgent care 3 times, completed 3 rounds of steroids, a z-pack, and tested negative for mono, Covid, and strep.

Despite my tendency to avoid conflict, something felt off, and I knew I wasn't okay.

I requested a referral to an endocrinologist, which I received, but they couldn't see me until after Christmas. Not wanting to wait, I found another endocrinologist who could see me on Halloween. At my first appointment, I was diagnosed with Hashimoto’s thyroiditis and hypothyroidism. She ordered a biopsy "to be safe," emphasizing that a finding warrants investigation. Even at the hospital for my biopsy, the PA questioned its necessity given my primary care's advice to wait a year.

On 12/22, my endocrinologist informed me that the biopsy results were suspicious for thyroid carcinoma. I returned on 1/5 to discuss the findings.

They had sent my sample for Afirma testing, a genetic test for medullary thyroid cancer, due to the unusual results and the aggressive nature of the potential cancer.

I was then referred to an ENT, who suspected the nodule might actually be a lymph node. A CT scan confirmed this suspicion, revealing a lymph node suspicious for thyroid cancer, yet with no nodules on my thyroid itself.

The decision was made to remove the lymph node, with intraoperative pathology consultation to decide whether to also remove the thyroid.

On 2/24, the lymph node was removed, but pathology was indeterminate, leading to the decision not to remove the thyroid.

The following week, I was informed that my results had been sent to a larger university hospital for further analysis and a second opinion, an ominous sign according to my ENT.

Ultimately, it was confirmed as papillary thyroid cancer that had begun to metastasize to the lymph nodes, indicating occult thyroid cancer, typically undetected until it spreads to the lymph nodes. Likely, there are microcarcinomas on my thyroid undetectable by imaging. Thus, another surgery is required.

My complete thyroidectomy is scheduled for 4/24.

Honestly, none of this truly sank in until I received a call from the hospital's oncology department to schedule a radiation consultation for post-surgery RAI treatment.

It’s been an incredibly tough start to the year, to say the least.

[boobblog]

I've had a couple of really good days. I got my drains out finally and can do people things again, like bend and twist, and breathe. The pain is still there from the mastectomy, but that's is manageable. I've been trying to explain it to Luke, because it literally takes my breath away. It's like millions of electrical fires snapping all across my chest. It's especially bad after I've done literally anything.

I vacuumed the other day, (don't worry, the vacuum is light) and wanted to die. I was so out of breath and sweating, it made me realize that although I still look "good," I have such a long road ahead of me. I'm not really excited about it. In fact, if I think about it for too long I get mad all over again.

In the next 2 weeks I have a chemo class, pre op testing at the hospital, dr. appts with my gynecologist and plastic surgeon, my port placement surgery then 2 days later my total hysterectomy. I feel like I've been run over and then eaten and spit out already. I'm so grateful that everything is moving quickly, and it's all because I've pushed for it to happen this way. Remember that unhealthy sense of urgency I mentioned, well these are the results.

I was diagnosed in September. It is the beginning of December now and all I will have to do next year is chemo. After that it's port removal and reconstructive surgery. But the cancer treatment will be coming to an end.

That's the hope anyway. I got my pathology results from the mastectomy. All clear margins, and she even said I'm cancer free. It was such an enormous weight lifted off my shoulders. The thing living and growing inside my body, attacking me and making me sick is out. I was overcome with emotion. I wasn't expecting to hear that. If I'm cancer free then why am I still doing ALLLLLLLL these things? I know the answer to that, but telling someone they are cancer free and then telling them to celebrate feels insulting when they can barely make it up the stairs in the hospital parking garage.

My breast surgeon followed up her statement about me celebrating with, "oh, it says here that your right breast had a cluster of cancer cells as well, it's a good thing we took them both!"

Hold the fuck on! I've had 79575675035 imaging tests ran, some of them were even repeated, how was this missed? Why was it not sent for mammoprint testing? How do we KNOW that it's the same as the boob bandit in the left breast? Did we get clear margins on it?

WHAT THE FUCK DOES THIS CHANGE?

The answer is, I don't know, and they don't seem worried about it, so the only choice I have is to trust them. I do. But, now, theres a tiny voice in the back of my mind telling me that this has to change something. The one thing I keep thinking is that because my cancer is so aggressive and walking around like it's got an invisibility cloak, it will come back, somewhere else. Just because I'm having a hysterectomy and will be on hormone blockers for 5 years, doesn't eliminate the other areas in my body producing the hormones that caused my cancer.

I should have gone to medical school, damnit.

I am consumed with all the horrific prognoses I've gotten. Arthritis, menopause, weak bones, blah blah blah.... In my mind, I'm still young and fun. In reality, my body is not able to keep up.

Sometimes I dream about when I was still dancing. How I was so in tune with my body that I could do all the things with my eyes closed. In my dreams, my body is still mine. It doesn't feel like that anymore.

I feels like I lost something, something I never knew how to keep, or that it could even be taken from me.

I think I'm just unsettled. My soul is tired, if that makes sense. I spend the majority of my time, hiding how I truly feel. My boy is in online school and home with us, so he sees everything, and apparently I'm an excellent actress, because this fool was just going about life like I have my shit together enough to handle his foolishness and teenager tendencies.

I lost my shit with him. To be fair, I tried having a feeling circle. You know, like in The New Girl. I even had a feeling stick, which was a ruler I found. But I started the feeling circle and I guess my feelings were still too strong to try and have a calm discussion about priorities and helping mom out more. I lost it. I wasn't yelling. We don't yell in our home.

But, I was saying, "I have cancer....", I just kept saying that, it's like I was caught up in a hamster wheel, just repeating it. Partly because I needed him to realize how serious this shit is, but mostly because saying it out loud to my son, made it sink in.

Still, today, it doesn't feel real. Also, why in the hell is it NOW that my hair is the healthiest it's ever been? That's pretty shitty Gods. But whatever. I'm alive, right. That's what everyone says anyway. It just doesn't feel like I'm living.

I have been reading though. Alot. It makes me want to write fiction books. I am able to lose myself in these stories. The room around me fades away and it's like I'm in the room with the characters, watching as everything happens in front me. It's such a personal and special experience. And because of the type of books I'm reading, sometimes it's kind of SPICY....(that last part MUST be read in Stefan's voice from SNL).

But did you know, not everyone is able to have images in their minds like that? Luke cannot imagine moving images in his head, and has a hard time visualizing things based on a description. It has something to do with our brains. However, he says when I write, he can. Maybe he is just being nice, but maybe I write things in a different way, a way that other neurodivergents can participate in. That's a fun thing to think about.

Maybe I can try that out here too. Chemo starts 1/14. I'll have 4 rounds 3 weeks apart that last 4 hours each time. That'll give me soooo much time to write. Maybe.

I haven't done much soul searching lately. It's been nice to turn my brain off. After our family meeting, Killian got his shit together and is back to being the best human on the planet, so I've just been allowing myself to feel safe and peaceful, for the time being. So, no big revelations this time. For the moment, I'm enjoying not crying.

[queeniecook]

Life update -

So, on May 24th I'm supposed to go down two and a half hours to another city and have surgery. It started out as a half removal of my thyroid but after looking at my patient portal, it looks like it's going to be a full. I'm only 36. Everything removed will be sent off to pathology (which is standard procedure) for testing to make sure there isn't any cancer. If it's a full removal, I'll have to spend the night in the hospital because it's a shock to your body kind of. Your thyroid is responsible for a lot of things. Thankfully, there is a thyroid replacement drug.

Now, I am only taking off two days from work after this. O_O. They recommend a week. We are short staffed and plus I kind of can't afford it, unless I use all my vacation time. Plus it's my weekend to do books. I'm not sure how my body is going to handle this. Then I go back down on the 30th for post op. Simba has an appointment for his kidneys June 1st.

I also have been keeping this all from my Mom, who is in the care center here and has battled depression, anxiety, bipolar disorder. Yeah. I'm going to have to tell her and I don't know how.

On top of it, my insurance is only going to cover some of all this. Ugh. Plus gas money.

I needed to vent. Prayers, good vibes etc please. Thank you.

[agilusdiagnosticsseo]

Pathology Services At Home

Experience the convenience of pathology services at home with agilus diagnostics centre.We bring top tier diagnostic services right to your doorstep ensuring accurate and timely results with out the hassle of visiting a clinic.Our trained professionals are equipped to handle all your diagnostic needs in the comfort of your home.In addition to pathology we also offer comprehensive health check-up at home packages.Regular health check-ups are essential for maintaining your well being and agilus diagnostics centre makes it easier than ever.Our expert team ensures a thorough examination providing you with detailed reports and personalized health advice. Choose agilus diagnostics centre for reliable pathology services at home and convenient health check-up at home solutions.

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[pellaeas]

oops my Unwrapping appointment is tomorrow. but i got my pathology results (still no breast cancer) and pulled out the ones from March to reveal that i am down 230g on the right and 236g on the left total, making me really optimistic about symmetry. Impressive how close that is given that my second surgeon never knew how much was removed the first time that made me assymmetrical. IIRC i attempted a water displacement breast volume test once and ended up somewhere around 250-260ml ea so... I should be pretty close to what i was imagining. if i am remembering my water measurement right then theres basically no way i could still be too booby

[expertacademicassignmenthelp]

The Physiology Of The Liver

The liver is a vital organ responsible for numerous functions including metabolism, immunity, digestion, detoxification, and vitamin storage. It weighs around 2% of an adult’s body weight and is unique due to its dual blood supply from the portal vein (75%) and the hepatic artery (25%).

Cellular Structure

The liver’s functional unit is the lobule, which is hexagonal in shape. Each corner of the hexagon has a portal triad consisting of the portal vein, hepatic artery, and bile duct. The lobule is composed mainly of hepatocytes, which have distinct apical and basolateral membranes. Hepatocytes are categorized into three zones based on their function and blood supply:

Zone I (periportal region): Closest to the blood supply, involved in oxidative metabolism (e.g., gluconeogenesis, bile formation).

Zone II (pericentral region): Sits between Zones I and III.

Zone III: Farthest from the blood supply, primarily involved in detoxification and biotransformation.

Blood and bile flow in opposite directions within the liver. The space of Disse, between the hepatocytes and the sinusoidal lumen, contains Kupffer cells (macrophages) and Ito cells (fat-storing stellate cells).

Development

The liver develops from endodermal cells of the foregut as the hepatic diverticulum around the fourth week of embryonic development. It undergoes complex differentiation influenced by various pathways (e.g., Wnt/β-catenin, FGF). By the sixth week, the liver participates in hematopoiesis, and hepatocytes begin bile production by the 12th week.

Organ Systems and Functions

The liver interacts with multiple body systems:

Digestive and Metabolic Roles: Aids in digestion, stores fat-soluble vitamins, and handles cholesterol.

Hematological Functions: Produces clotting factors and proteins.

Detoxification: Metabolizes drugs and other xenobiotics through phase I (oxidation, reduction, hydrolysis) and phase II (conjugation) reactions.

Bilirubin Metabolism: Converts heme to unconjugated bilirubin, then conjugates it for excretion.

Hormonal and Protein Synthesis: Involved in thyroid hormone activation and synthesis of nearly all plasma proteins.

Related Testing

Liver function tests (LFTs), including ALT, AST, bilirubin, alkaline phosphatase, and gamma-glutamyl transpeptidase (GGT), help assess liver health. Imaging techniques like ultrasound, CT, and MRI are also employed to identify liver abnormalities.

Pathophysiology

Cirrhosis results from chronic liver injury (e.g., due to alcoholism, hepatitis B and C), leading to fibrosis and necrosis. It causes symptoms like portal hypertension, coagulopathy, and jaundice. Hepatitis viruses (A, B, C, D, E), autoimmune diseases (e.g., primary biliary cholangitis), and metabolic conditions (e.g., non-alcoholic fatty liver disease) also contribute to liver pathology.

Clinical Significance

Understanding liver physiology helps manage conditions like viral hepatitis, alcoholic liver disease, benign liver lesions, and liver cancers. Early detection through appropriate testing and management strategies is essential for preventing end-stage liver disease and improving patient outcomes

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[lastlycoris]

re: breast cancer ai, is the testing that would need to be done to make sure it's an accurate result invasive or expensive or both?

It seems I jumped the gun when I reblogged that article. Despite them using a mammogram on the post's images, this AI innovation is for pathology, not radiology. I was talking about computer-aided detection for mammography, but this is a different beast entirely.

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So some background, DCIS is known as ductal carcinoma in situ and is a pre-cancerous or a non-invasive cancerous lesion of the breast, depending on who you ask. Approximately 1/3 of people who have this develop actual breaat cancer aka it leaves the duct and start invading other things. So to make sure cancer doesn't develop, people are often recommended to excise it or even get a mastectomy - the removal of the whole breast - to treat it.

But doesn't that sound a little extreme when 67% of people may not even develop it?

I mean, look at prostate cancer, where urologists watch and wait to see if cancer will progress using labs, imaging, and occasionally biopsy. Because by the time you are diagnosed with prostate cancer, you're more likely to die from something else like a heart attack, old age, etc than from the cancer itself because it tends to grow so slowly. And getting a preemptive removal of the prostate - prostatectomy - has a lot of unwanted consequences including urinary incontinence and erectile dysfunction.

Wouldn't it be nice then if we could figure out what forms of DCIS would turn into full-blown cancer and what sort would behave more like prostate cancer?

Well, we do have some tech in the works, I believe, in the form of RNA sequencing, where you look at the cancer's genetic profile to see if it will go bad quickly. But RNA sequencing is expensive, and I don't believe it's common place yet.

And that's what the MIT research comes in. They are stating they can predict the behavior of DCIS, whether it'll act good or bad, by taking tissue samples of past known DCIS (and already having documented their behavior if they turned into cancer or not and how fast they do), using a chromatin stain to create slides, and feeding them into an AI to generate a predictive model that could tell from a tissue slide how DCIS will behave based on the model.

Staining and creating slides is cheaper than doing RNA sequencing according to the article ( I do not have the numbers on hand, but it seems like it'd be right), so this is a big deal as it both is cheaper for the patient and may allow a patient to avoid unneeded surgery.

Of course, the model needs to be validated to see if it works in practice, but it sounds promising.

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As for what I was taking about erroneously, it's called computer-aided detection, and it analyzes mammogram images.

The CAD software can detect areas that are suspicious on a mammogram and alert a radiologist to them. The problem is that it can mark areas that may seem suspicious to the computer but seems normal to the mammographer. But what does a mammographer do with that information then?

The normal workflow of mammography is that you find a suspicious lesion on screening mammogram, ask the patient to come back to take diagnostic / magnified / compression images aka the breast getting smooshed views (more cost and discomfort), and if it's still suspicious with additional views you do a biopsy (invasive).

If the CAD is wrong but you test, you have done unnecessary imaging or worse even an unnecessary biopsy.

But if you the mammographer say that the CAD is wrong when it's right, you just missed cancer and put yourself in a very tight spot if they run the CAD software on your images.

To answer your question from what I was referring to, yes, the testing to confirm all the findings that the CAD points out would add a lot of unnecessary tests and biopsies for the patient.