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A new treatment combining ReCET and semaglutide could eliminate the need for insulin in type 2 diabetes, with 86% of participants in a study no longer requiring insulin therapy. The treatment was safe and well-tolerated, and further trials are planned to confirm these results.
Groundbreaking research presented at UEG Week 2024 introduces a promising new treatment approach for type 2 diabetes (T2D) that has the potential to greatly reduce or even eliminate the need for insulin therapy.
This innovative approach, which combines a novel procedure known as ReCET (Re-Cellularization via Electroporation Therapy) with semaglutide, resulted in the elimination of insulin therapy for 86% of patients.
Globally, T2D affects 422 million people... While insulin therapy is commonly used to manage blood sugar levels in T2D patients, it can result in side effects... and further complicate diabetes management. [Note: Also very importantly it's fucking bankrupting people who need it!!] A need therefore exists for alternative treatment strategies.
Study Design and Outcomes
The first-in-human study included 14 participants aged 28 to 75 years, with body mass indices ranging from 24 to 40 kg/m². Each participant underwent the ReCET procedure under deep sedation, a treatment intended to improve the body’s sensitivity to its own insulin. Following the procedure, participants adhered to a two-week isocaloric liquid diet, after which semaglutide was gradually titrated up to 1mg/week.
Remarkably, at the 6- and 12-month follow-up, 86% of participants (12 out of 14) no longer required insulin therapy, and this success continued through the 24-month follow-up. In these cases, all patients maintained glycaemic control, with HbA1c levels remaining below 7.5%.
Tolerability and Safety
The maximum dose of semaglutide was well-tolerated by 93% of participants, one individual could not increase to the maximum dose due to nausea. All patients successfully completed the ReCET procedure, and no serious adverse effects were reported.
Dr Celine Busch, lead author of the study, commented, “These findings are very encouraging, suggesting that ReCET is a safe and feasible procedure that, when combined with semaglutide, can effectively eliminate the need for insulin therapy.”
“Unlike drug therapy, which requires daily medication adherence, ReCET is compliance-free [meaning: you don't have to take it every day], addressing the critical issue of ongoing patient adherence in the management of T2D. In addition, the treatment is disease-modifying: it improves the patient’s sensitivity to their own (endogenous) insulin, tackling the root cause of the disease, as opposed to currently available drug therapies, that are at best disease-controlling.”
Looking ahead, the researchers plan to conduct larger randomized controlled trials to further validate these findings. Dr. Busch added, “We are currently conducting the EMINENT-2 trial with the same inclusion and exclusion criteria and administration of semaglutide, but with either a sham procedure or ReCET. This study will also include mechanistic assessments to evaluate the underlying mechanism of ReCET.”
-via SciTechDaily, October 17, 2024
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Note: If it works even half as well as suggested, this could free so many people from the burden of the ongoing ridiculous cost of insulin. Pharma companies that make insulin can go choke (hopefully).
#would be super interested to hear from people with expertise in the area about how this sounds#obviously it's a small sample size#but they're going to do more trials#and LOOK at that effectiveness rate#insulin#diabetes#healthcare#medicine#diabetic#type 2 diabetes#public health#medical news#good news#hope
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It's annoying when people see how much CPD has dropped and cry that it's because of the timeslot. It has been in the timeslot for a decade..... so
Yeah I'd say the discrepancy between live numbers for shows like Med and Fire (or other 8/9pm shows) compared to PD should factor in time slot.
But you can't deny PD has fallen when comparing it with itself over the years, in the same time slot. The ratings are all listed online. And again, the fall in ratings includes factors like the decline of network TV, natural falloff of audiences, competition, and changing mediums for entertainment. But if we're looking at external factors, it's only fair to look at internal as well for why people aren't sticking around anymore or are choosing other shows- the writing is weaker, the procedural cases are weaker, and the cast has lost major pieces over the years.
#anon ask#last ratings question for a while#unless there's an interesting new talking point to hit on
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He is hidden in the howling void. He is hidden within the tempest. He has braved the storm And the darkness And the pain. And He whispered to the vessel. All this time He whispered And delighted And seduced, And the vessel did obey, For none shall be more mighty And none shall be more wise Than the King Himself.
And the Lord of Time Was blind And vain And knew nothing.
There is the Toymaker, the God of Games. There is Trickster, the God of Traps. There is Maestro, the God of Music. There is Reprobate, the God of Spite. There is the Mara, the God of Beasts. And the Threefold Deity Of Malice, and Mischief, and Misery. There are Gods of Skin and Shame and Secrets. There is Incensor, the God of Disaster, And Her children called Doubt and Dread.
And standing on high Is the Mother And Father And Other of them all: For the God of all Gods Has returned. And His names are many.
His name has been Set And Seth And Sithifer. And His One True Name Forevermore Is Sutekh.
Sutekh is the God of Death And by His hand All creation shall fall Into dust And ashes And ruin.
#Doctor Who#doctor who spoilers#The Legend of Ruby Sunday#holy shit what an episode#apparently the ratings sucked but my neurons have never been so engaged#I love this new Pantheon mythology they're bringing to the show#this season has been so good#love to see some actual fantasy in my science fantasy#magic and myths and gods and cosmic horror#I am RIVETED. I am so so so interested in this new worldbuilding.
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It's midnight so I'm gonna ramble again but about animation/cartoons as a whole included with my lack of knowledge about the industry
A few weeks ago, I remember watching some video about Cartoon Network or something and the guy doing the essay mentioned something like "With the rise of streaming and online as a whole, there is a loss of connection with parents and their kids because back then, you could watch the same cartoon with your kids and recognize who that is". They absolutely did not say those exact words but something along the lines of it, and it's stuck to me for days because it's true! Like I don't think kids nowadays have that kind of connection other than theatrical kids movies, which sucks I think moments like these are precious to have.
Another thing is that I think people kind of underestimate how popular cartoon/2d/3d shows are with adults? Especially young adults because the people who grew up with like, 1990s-2010s shows are probably mostly grown adults now. Probably the best recent example of this is Adventure time and how (I think) big Fionna and Cake is. Like I could go on Twitter and be spoiled hell and back on the newest episodes LOL. How about Owl House and Infinity Train? Bluuey too?? I don't know, but with the writers strike and how swept under the rug animation is, especially on streaming, it just kind of sucks where the current state of animation is right now for everyone as a whole
#quick one (compared to my other rambles LMAOOO)#but yeah it kinda sucks. like after fionna and cake. what else am i gonna be looking forward to?#like back in 2015 or something. i had so many shows to look forward to for airing#gravity falls. adventure time. steven universe. star vs. mirabug (unfortunately)#maybe ive grown up and i dont keep in touch anymore but now the only show i have to look forward to is fionna and cake. but then what?#any new shows are just gonna get shut down after season 1-2 (INSIDE JOBBB I WONT FORGET YOU)#and old shows getting reboots are either gonna suck (fairly odd parents) or have no chance at all of being picked up again (INFINITY TRAINN#in exchange of easy to access shows and the loss of tv. the industry has gone haywire with new shows#in hopes to get that one hit show. and it sucks w the rate of how many of these r coming out#many of the shows are left under the rubble if they dont get enough interest. even those that r popular OWL HOUSE#sorry i rambled in here too :skull: but it makes me sad bc i love cartoons so much#etc#diary
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I've been on an Elder Scrolls binge lately, I'm literally doing like 9 concurrent playthroughs across 6 games and idk what kind of virus I got where I'm this adhd/autistic about a series that won't get a sequel for another decade (and will likely be mid as hell if Starfield is anything to go by)
#made it out of the sewers yesterday in Arena and then quit when I got to Hammerfell#then switched over to Daggerfall and made like 5 ladies & did a few Mages' Guild quests on my Argonian before switching over to Battlespire#and I made a Dunmer archer lady and I went through the first 2 levels before switching over to Morrowind#where I made an Orsimer lady who exclusively attacks via punches#and then I went over to Oblivion and all my saves got deleted for some reason so I started literally 6 new files:#Argonian assasin lady#female Altmer archer that uses summons to draw aggro#male Bosmer that uses a warhammer that I made even shorter than normal with console commands#female Orsimer mage#male Redguard pugilist#female Khajiit that I tried really hard to make look like my daughter#but the Oblivion character creator was not cooperating with me#and then today I booted up Skyrim (Nolvus) and fucked around with that modlist#hell I even booted up ESO yesterday but I honestly lost interest because the MMO format doesn't appeal to me#but I do want to experience everything I can eventually since TES6 isn't dropping for another 17 years at this rate#and if it does miraculously release in our lifetime it'll be incredibly mediocre so it'll take another few years for modders to fix it#I'm so fucking close to emulating an N-Gage and playing Shadowkey
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Hey any chance people would be interested in commissions?
Just most of the oc requests have been scenes, when I was asking for characters for practice.😅
#fairly oddparents#fairly oddparents a new wish#ace attorney#phineas and ferb#milo murphys law#my little pony#mlp#clowncore#kidcore#honestly willing to draw a lot#I’ll have rates up tomorrow if theirs interest?#commission#art commisions
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What people are are saying happened at today's UAP/UFO Congressional hearing: ALIENS ARE REAL AND WE'VE GOT 'EM
What actually happened at today's UAP/UFO Congressional hearing: A former intelligence official, under oath, stated that he has interviewed people who have claimed to work on secret UFO recovery programs.
Also, he turned in evidence that was already declassified and signed off by the Pentagon.
And he was joined by 2 Navy pilots who, also while under oath, gave testimony to their experiences with UAP. One of the pilots was David Fravor who witnessed the famous "tic tac" ufo.
#ufos#the big thing is that congress is giving time and attention to the topic#but nothing brand new was revealed#also the Fed raised interest rates for the 12th time in a little over a year#ufology
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goodmorning whiskey!!!!!!!!!! um. here is some more parahumans stuff for u........ i'm not. including any of the specific power classifications stuff bc there r PAGES of like. tinker ideas. tinker subclasses. ways to write interesting tinkers. common types of powers. ways to generate tinker powers. etc. for pretty much every category on here. that would be insane to send u. there aren't any Major spoilers in the docs afaik. but the ones that are there r like. big end-of-novel payoff. so. if u want i can send those over!! otherwise. idk. if theres anything that strikes u for the greats (auugh. going 2 be so normal over them btw have i mentioned this??) or just in general power wise. or honestly other worldbuilding there's so much. yeah. lmk & i'll scrounge around for u? ur worm sourcer............. anyway CATKISS.GIF hope ur having a good mornign!!!! sharing my matcha with u <333333
RUBS MY GAY LITTLE HANDS TOGETHER LIKE A FLY. OUHGHHHGH I HAVE IDEAS FOR THE GREATS ALREADY. OUUWHHHHH THANK U ROS THANK U IM GOING 2 BE THINKING ABOUT THEM ALL DAY!!!!! how many classifications do parahumans typically have??? how many is too many??? bc i have three different ideas for strider but idk if i wanna just pile them all on him at once yk?? i know some of them have two classifications w different powers but would three different powers be too much??? the thoughts are thunking rn......
#all three of them would be like. low rated powers so he wouldnt be super op but is three too much????#hes a mover for sure but i also have ideas for stranger and striker powers for him and i cant decide!!!!#i am skimming thru each of the classification pages on the wiki and Yeah Holy Shit!!! thats a lot!!!!#its so fujcking. interesting. ily worm power system <3#new haven wards
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Hey y'all, possibly one of those questions with a ridiculously obvious answer, but can iron-deficiency anemia make you super tired? And if so, how do you fix that? (I got blood test results back but haven't talked to my doctor yet. He'll probably put me on iron supplements or something but I am so tired right now)
#the person behind the yarn#medical mention#blood mention#my ferritin level is 3#which I don't quite have context for but it always makes me laugh when my numbers are comically low#like. 3???? 3 feels like way too low a number to be used in a medical context#iron sat percentage is 8%. do I know what that means? not really!#is 8 also comically low to me? definitely!#it's like the opposite comedic effect of nurses doing the intake triage stuff at the doctor's office#my heart rate always gets an interesting reaction with new nurses#because I'm sitting there looking totally calm and my resting heart rate is like...140s#I always immediately tell them that this is not unusual to me#but it ALWAYS gets a double take with new nurses
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#personal#internets#at this rate I've unfollowed both of the kinda.. 'controvercial' blogs I've been following#since there was a good chunk of actually good takes about how bad media is now and society and braindead internet 'activists' that-#-had it too good in their western countries and NEEDED to invent the reason to bully and excile people#could honestly resonate with it despite some other posts causing genuine pain. but mostly about terribly handled media#like you know that thing when corporations do terrible ass rep to pretend that they care for minorities#or artificially fabricate online backlash against their new actors to show investors that people show interest for their product because-#-of all the clicks on their article?#like discussion of this kind sorta keeps me sober#as a person with BPD I get contaminated by opinions VERY easily and as an autist I will believe everything if it is put together 'logically#that's why I HAVE to be exposed to every possible opinion so I am forced to make out my own rather than being swayed anywhere#but at this point those blog became kinda.. bad? like they don't just have 'opinions' but they hate just to hate#but now my dashboard and recs are full of exclusively things I can fully agree with and I am scared that it will rot my brain#like.. emotions are always the same. where is the 'wait WHAT' effect? where is anger? where is self-reflection?#but ALSO I realized that 'those' blogs are no better than those western 'warriors' I despise and they become narrow-minded too in the end#they advertise themselves as 'open to debate' only to always sway debate into trying to win and not into actually discovering the truth#I cannot trust any side because they're all narrow-minded and hostile but I cannot trust people without any side because-#-they're fence-sitters without morals that side with the winner#is there a secret third thing? like is there a way to not take a side but to still HAVE ideals and opinions?#my problem is that if I am not exposed to people that trash everything I value I forget why AM I valuing [a thing] to BEGIN with#and that won't do will it
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preemptively sorry for how fucking long this is it is YOUR FAULTT THOUGH!!!! large bowl of seeds for u. it is almost 2am sorry.
SO. there are. two ways to assign the prime defenders powers etc. the first way is just, like, categorize their existing powersets within the prt framework, & the second is to give them entirely new abilities based on the way worm works. delightfully, all the powers they Do have work really well for the most part, so even that doesn't require a ton of shuffling.
categorizing their pre-existing powers:
wiwi-- breaker w/ a shaker subclass. neither of them rated very high, but that's already a rare and versatile enough combination!!
dakota-- brute babeeeey!!! brute/mover its so straightforward. hell yeah babey. i don't know what he'll end up looking like post-heart removal & stuff but my guess is that'll end up looking more like a mover/striker.
vyncent-- now THIS one gave me trouble. i... hm. to say this without talking about stuff that i don't think has come up much already, (hey!! you're at that clockblocker pov! directly related to what flechette says!) i'd call him a grab-bag cape, irt the greats at least. post-greats-- again, i don't know what his powerset will look like after this arc! but if he's going all in w/ the fire magic, that would for sure be some striker shit! :]]]
giving them new powers... man i'm reining myself in so hard from five more paragraphs on Why exactly i'm saying all this.
wiwi still breaker for sure, maybe breaker-master, maybe master-stranger. yknow. powers are fluid, the prt categories are pretty rigid. i... don't know. enough about his situation yet to be clearer than that vague idea yet-- i really like the idea of him just. ditching his body & using a noncorporeal form but he still has to keep an eye on his body i think that's great. the noncorporeal form would b able to change its visibility but still b limited by proximity to the body. & fluctuating energy shit powered by fluctuating amounts of recent-death in the area, maybe probably also limited in that it's only accessible in his breaker form.... also i think u will appreciate this style note from the [UNNAMED PARAHUMANS TTRPG] i'm referencing a lot here.
dakota--in this situation he probably would not. have that mechanical heart and shit. he' would still be a mover/thinker-- thinker rating is for faster mental processing + senses imminent pain for the people in his immediate vicinity. not danger, just pain; it immediately registers ambiently & can be generally traced back to whoever it is. no he can't turn it off ever, it manifests as feeling a similar level of pain, yes it works on himself. + mover-- he can fucking fly. no super strength, just very fast flight & the general "won't splat himself flying into something" capabilities, which meshes well w/ the faster processing & reflexes. i'm split on how exactly this would work mechanically but i will NOT go into that now. i am also not going into the 15k discussion in my brain on why dakota 'notoriously bad at thinking about things' cole would be a thinker but u gotta trust the process ok??
vyncent-- trump!!!! somehow this is the only straightforward one to me? he can copy powers at the full strength or ability level of the original for an unspecified amount of time that's usually 1-30 minutes by touching the cape. crucially, he doesn't have any edge on how to use these powers + can easily misuse or become extremely overwhelmed by them. he's easily the most powerful out of the three of them <33
ashe-- ashe is NOT HERE currently and also it's 1:30 am so i gotta go fucking sleep soon BUT they would be a master. easy. :o) they can make some lil guys n do stuff with them!!!!
in general these are pretty fucking cracked abilities, all of them would b oosely above a seven or so in a number rating once they're really settled in their powers-- this is mostly because i'm assuming that they would still be heirs-apparent to the prime force equivalent, which would b the triumvirate :]] anyway. good lord. this is like the cliff notes edition of what i've been thinking and scribbling in the notes app for the past several hours. sorry if it's fucking incomprehensible. gn!!! <333
AAAAAH FUCK YESSSSSS OKAY OKAY OKAY my response is probably going to be equally as long. so it's fine. oooouh buddy.
I KNOW WHAT BREAKER MEANS NOW !!! I dontttt think ive learned shaker yet. breaker is like.... breaking the laws of physics/shifting planes or whatever. PERFECT for william hell yes. for putting them actually in worm world ... ughhhh breaker/master william is REALLY cool. I havwnt learned stranger yet but i think he would develop a complex over being classified as stranger <3 (like how weld doesn't like that he's classified as a brute even though that's not exactly what it means, he just doesn't like the word) . GODDDD just thinking abt putting pd boys in worm is fucking me up haven't they been through enough. I want to see them all in a fit of despair. william ditching his body is SO good I miss when he would do that, also the powers being limited by how far away he is AND THE AMOUNT OF RECENT DEATH IN THE AREA. holy shit. that's so fucking good . im sure he would not overthink at all the fact that he is stronger when more people around him have died . I'm sure he'd do awesome in the leviathan fight for sure for sure .
DAKOTA BRUTE <3 DAKOTA BRUTE/MOVER I LOVE THIS A LOTTTTTT hellbyes. awesome. it's so perfect for him <3 worm world I'm SURPRISED u didn't stick with brute for him. eyes emoji. I trust your judgement but now i am Thinking... Hmm..... YOU BRING INTO QUESTION something I have been thinking about. and I'm going to probably get derailed a little here but stay with me. how the way powers manifest directly relate to the trigger event. because for a WHILE before we learned taylors I was like "OH i bet the powers are going to be directly related to what traumatic thing happened to them" and then we learn about taylor and grue and a couple more and I kind of lost that theory because while you can. technically draw relations between their powers and their events it seemed like too much of a stretch to do . HOWEVER now my thinking has changed AGAIN and I think the powers ARE related to specific trigger events but it's not as straightforward as "oh something scary happened to you with bugs so now you have bug powers" I think it's gonna be more complicated than that. WHICH. THE WAY THIS RELATES. BACK ON TOPIC NOW. to DAKOTA . assuming his trigger event is still he and katori falling off the building I think it's AWESOME that his powers would manifest as FLIGHT for one. and the fucking. pain sense thing. fuck me up. dakota extreme hero complex cole would be so fucked up by a power where he ambiently senses pain from the people around him at all times and cannot turn it off. I'm sure he would feel so normal about being around william chronic pain wisp 24/7. also I can SO CLEARLY imagine how this power specifically would lead to him getting super overwhelmed in chaotic situations like he does in canon. and just fucking. bolt out of there because it's too much. again. he'd have such a wonderful time in the leviathan fight
I AM AT CLOCKBLOCKER POV !!!! actually technically I'm on kid win pov now but I haven't finished his chapter yet. vyncent grab bag cape..... yeah... I think it would be EXTREMELY funny imagining the PRT in pd world trying 2 classify vyncent like. what the fuck does this kid do . what do we do with him. hes got other guys in his head that give him powers. is he a master??? no he can't fucking control them. is he a striker??? only SOMETIMES. is he a blaster?? AGAIN ONLY SOMETIMES. cannot classify him bitch!!!!!!!! giving him worm powers though.. UGH. being able to touch someone and COMPLETELY copy their powers but only for a short period of time???? I fucking love that a lot. he WOULD be the most powerful out of them!!! I can hear taylors inner analysis dialogue about him now and it's very similar to the clockblocker "DONT LET HIM.TOUCH YOU" panic. loooove imagining this playing off of the rest of pd,,, i know there was AT LEAST one time where he had william sort of transfer some of his ghost powers for a minute? I think it was during the lich fight in the theatre but i just remember vycnent floating and going intangible and NOT KNOWING how to control it or anything. loveeee that. in world dynamics I feel like vyncent would be a late addition to their team (instead of coming from another world maybe he just. had his trigger event happen way later than the other two..or something.) and not trusting them as much at first/being REALLY shaky using either of their powers but after a while being really comfortable in a fight with using either Williams or dakotas powers in a fight. Just like. imagining the fluidity of how they'd work together in a tense situation assuming they're not being complete dumbasses <3333 UGH it's really good
AAAASHE ASHE ASHE IM SOOO SO GLAD YOU INCLUDED ASHE IN THIS I miss him.so much every day. from what I know so far master involves having/making/controlling some sort of minion (cannot think of a better word than that rn) AND I THINK THATS REALLYYYY perfect for ashe. i assume he would actually work pretty closely to canon in that his limitation would be the book? or if he doesn't have the book maybe his limitation would be a) having only a few different types of things he could summon (the big hand, the water fairy, duck etc) and/or b) only being able to control them.for a short amount of time after they're summoned so he has to be quick about dismissing them. can't keep the demon hand around for too long or it might start picking things up and throwing them at random. putting teammates in danger bc he can't control it anymore etc etc. alsooooooo in clockblocker pov they VERY briefly mentioned the possibility of having secondary trigger events (?!!!!?!?!) and you know I locked onto that SO FUCKING HARD. ashe being born with powers and then his secondary trigger event being his mom's death <3 im.NOT even going to attempt to talk about how the trickster would work in worm world/if it would even exist in this setting bc i don't know enough about the types of powers and things yet..but just know. I am keeping this in the back of my mind "this is a fun surprise tool that will help us later" style
#also side note but can i say. thw whole time i was reading the leviathan fight a persistent thought in the back of my mind was#“man i really wish they had a cape here who could control water- THEY NEED TIDE... THEY NEED TIDE SO BAD”#so like..really normal about putting prime defenders SPECIFICALLY in the leviathan fight. teehee (<< most diabolical laugh youve ever heard#I HAVE A LOT MORE THOUGHTS ABOUT WILLIAM TOO BUT..HMMMMMMMMM DONT THINK I CAN SAY SOME OD THEM YET#EXTREMELY interested 2 see whether ur thoughts on specifically him and dakota#will change after both the training arc and certain other events <3#hehehehehehehee#GOD I CANNOT STOP IMAGINING. PD IN WORM.WORLD. they would suffer so fucking badly man.#william wisp guilt complex about his powers turned up to 200#HAVING A LOT OF THOUGHTS ABOUT ASHE ALSOOOOO . AS ALWAYS#now that i know more abt power classes i am VERY confidently going to put mark down as a tinker/striker.#with the tinker rating being SLIGHTLY higher than striker bc he uses the things he makes to amplify his naturally weaker striker powers.#tiiiiiide im thinkingggg would be. whats the elemental one.#not breaker bc thats specifically about breaking physics and i dont think that works for him.#is it shaker?????? i dknt think ive learned shaker yet.#U ARE MORE EQUIPPED AT THIS THAN ME whats tide. tide would also for sure be a case 53 right. i havent exactly learned what that means yet#but im assuming its the whole artifically giving people powers thing and. thats tide baby. idk if clones would work in worm world#so maybe its him and his regular siblings all being specifically given elemental powers#so they could work together as some super crazy powerful team. and then. that Doesnt happen <3#(idk if u have listened to the tide oneshot yet but. its good. if you ignore dodgeboy)#ANYWAY. i should start getting ready for work now. im having so many thoughts about this norlw#hollyyyyyy shit#infected my brain with worms (pun intended)#asks#friends!!!#intertexts#wormposting#jrwi pd#<< only tagging so i can find this later when i learn more and can properly yell about it#new haven wards
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the absolute rabbit hole that is looking into the COL/housing/wage crisis in the US...
#wasted yet another 3 hours of company time on graphs and metrics and cyringsobbing#'250k is the new 100k' how about you explode. the median individual wage is still 50 fkn K dude.#and you can be in the top 75th/90th percentile and STILL you cant afford a house rn. what are we doing man...#all started with my parents sending my brother and i a stupid nyt calculator about housing vs renting affordability#as if the reason renting beinthe less expensive investment isnt directly due to the explosion of housing prices and fuckoff interest rates#'oooh interest rates were higher in the 80s ooh' well wouldnt you know it the avg cost of a house was still reasonable compared to wage!!#now we're looking at ratios similar to the fkn 2006/7 bubble as a new norm. and not a bubbke#*bubble
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Parasite (1982)
"That thing on your stomach..."
"A new strain of parasite. I deserve it, in a way. I created it."
"For the Merchants? Why?"
"I thought for the government. They're so mixed up with the Merchants now, they work for one another. This 'thing', as you call it, is growing. It's dormant now but it will soon grow larger... and kill me."
#parasite#1982#blood tw#horror imagery#video nasty#horror film#charles band#alan j. adler#michael shoob#frank levering#robert glaudini#demi moore#james davidson#luca bercovici#al fann#tom villard#scott thomson#cherie currie#vivian blaine#james cavan#cheryl smith#pretty meh post apocalyptic horror which would probably have been entirely forgotten to the mists of time if it wasn't for the double#whammy of having been classed a video nasty by the bbfc (which granted every film on that list some measure of immortality) and for being#an early leading role for Demi Moore (how much do you wanna bet it isn't on her CV tho...). actually it isn't without interest for its own#merits: the vaguely sketched in details of this post apocalyptic society (some time later‚ which is always most interesting‚ to see how ppl#have adapted and evolved to a new normal) and the shady implications of whatever the Merchants are‚ that stuff is all genuinely very#intriguing. the main thrust‚ tho‚ the parasite stuff‚ that's somehow less stupid (and much less clever and much less original). Moore is#fine‚ nothing more (potentially controversial take? i don't rate her as an actor) and the rest of the cast is nothing to write home about#the fx are sometimes goofy and sometimes gore splattered ingenuity; the final act contains some real gruesome body horror#oh and as the poster subtly suggests‚ this was shot for 3d so expect much pointing into the camera and stuff jumping up
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how are people scared of bats :(
#theres a lot of misinformation about bats and it makes me sad :(#like did you guys know that despite bats being known for having rabies only 0.5% of bats actually do#and bats dont bite...not even vampire bats do#tho it is more reasonable to be afraid of vampire bats as the rabies rate is 10% and they do drink blood#but they only live in central and south america and mainly go after cows#and when bats swoop down at you theyre actually just eating the bugs that are trying to bite you#bats are actually really good for the environment too#if there werent any bats a lot of really good fruit wouldnt be able to grow#no bats? no mango banana guava avovados or tequila#and reduced amount of rice citrus strawberries coffee chocolate and cotton#people also study bats' echolocation to find new innovative ways to help blind people#and bats arent affected by many deadly diseases and they have a very low risk of cancer and their dna is similar to humans#this means that bats could possibly be the key to curing cancer as well as slowing down the progression of aging#and by that i mean that it could delay the symptoms of getting older#such as aches and pains memory issues risk of certain diseases and physical changes#idrc about changes in appearance that much but its interesting#anyways
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jesus christttt im not surprised at all to hear that the knuckles series focuses on wade and other human characters a lot i saw this coming a mile away with how almost all the news we were getting before the trailer came out was about the human characters/actors and not about knuckles (or sonic or tails or any other animated characters) but the fact that somebody calculated how many minutes of screentime knuckles has and it came out as LESS THAN HALF OF THE ENTIRE SERIES' RUNTIME when the series is NAMED after him is ridiculous. after this show comes out wade will likely have more screentime and overall plot relevance in the entire scu than tails does. did they actually think wade is a popular enough character for people to be down with this. what the fuck
#was gonna pirate the series but at this rate i might not watch it at all LMAO or at the very least only watch the parts with team sonic#because my interest in this series is dropping every second and i already wasnt very interested in it.#and i love knuckles so you know theyre doing something wrong if knuckles getting his own series isnt interesting me#the thing about wade is i dont even hate the idea of human characters. i dont think its bad for human characters to be present#and i dont think its bad for them to be involved in the plot and have relationships with the existing sonic characters#i personally didnt mind the wedding subplot in the second movie and i know a lot of people hated it#but. it becomes a problem when the random humans are overshadowing the characters people are actually here to see#like the show is literally called knuckles and all the marketing focuses on knuckles but its mostly about wade. allegedly.#and . i wouldnt have minded knuckles having a human costar. but again. they should be getting equal or less focus not more.#and also. its fucking wade who cares about wade enough to want this. would have been more forgiving if it was maddie or jojo or something#because i actually care about those characters. and also theyre not cops#for a moment i was willing to believe that the complaints about wade having way more screentime than knuckles#were a little exaggerated since a lot of people just get mad when the human characters have any screentime at all#but then i saw the article showing that knuckles really did show up for less than half the show and i was like Ummm. What#sorry for being so negative lately#its just that every new piece of info we get about upcoming scu projects has me like that reaction image of the guy holding a cigarette#like WHAT ARE THEY DOINGGGGGGG
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