#have some magnesium glycinate supplements

[mashriqiyyah]

i wanna kill myself.. life's so hard

No. You Don't!

All you want is to live a life different than the one you're living rn.

And yes... it's hard...but this is a vulnerable moment. It'll pass. And you'll know you so badly wanted to live. Please dm me if you're a sister. Be patient with yourself and your situation...❤️‍🩹🤍

May Allah heal you and grant you better 🌷

[funnuraba]

I've been compiling a list of weird or embarrassing warning signs of ME/CFS or Long Covid. Perhaps you have noticed these in yourself, but they've seemed too minor, confusing or embarrassing to ask about or look up. In any case, I've gathered these from online posts, so you'll never know which, if any, have happened to me, which I think is a very clever move on my part. Okay I did start complaining near the end, but I added some helpful solutions you may purchase, which I had to figure out on my own.

Actually I'm gonna lead with the absolute weirdest one, because it's a sign of the initial acute Covid infection that can be hard to detect now. I've only seen a post about this once, but a bunch of people agreed with it and said it happened to them:

If the skin on the soles of your feet is suddenly super thick and dry, that is associated with the initial 'Vid infection. I don't know how long this is supposed to last, but it was vouched for by several accounts I felt were trustworthy. I had to look up "Covid feet soles" on Twitter to check for this, forgetting that Twitter search now just randomly shows you posts with only one word that you entered, and I didn't find the post I remembered but I am not going back in there.

Extremely ridged and brittle fingernails (apparently this is showing up a lot on beauty subreddits and such)

Shrinking or vanished half-moons on the fingernails (I don't know if the level of shrinking is random, or related to severity/length of time)

Thinning hair/balding: seems to follow the usual pattern of your dominant hormone, so estrogen-heavy people get thinning hair, particularly along the center of the scalp, and testosterone-heavy people get receding hairlines and bald spots. There's no single pattern that everyone with ME gets. (Although ME is much more common in AFAB people.)

Incontinence that's not associated with age or childbirth, etc. In this case it's due to nerve damage, not weakening muscles.

Pins and needles, or sharp shooting pains in your fingers and toes: this is called neuropathy and it's also a sign of nerve damage. (I got a ton of this and thought I might be pre-diabetic, because that's all that came up when I searched! I asked doctors about this and they just went "oh 😐 " so I exercised a bunch and probably made myself much sicker XD. Anyway magnesium supplements helped a lot with this! You need a magnesium complex that includes magnesium glycinate, because other types are really hard for the body to absorb.)

Sudden acid reflux and heavy gas, loss of tolerance for foods you could once eat: this is associated with aging, but if it's really really bad? Like remember a year or so ago,when suddenly everyone was posting about how their tummy hurt and they were being really brave about it, and it kind of came out of nowhere and had never been a meme before? Almost like it was sort of new for this to be so very widespread? Yeah, Covid can fuck your system up real bad, and this is a common comorbidity of ME called gastroparesis. Basically your stomach muscles are as weak and slow as your other muscles, so your food sits in there for way too long. It often comes with Mast Cell Activation Syndrome, which is bad news and means a ton of new sensitivities, to food and other things. MCAS goes along with a lot of other unexplained body syndromes that doctors don't really "get" or care about.

Being super itchy in one spot for no reason: this is a histamine dump. MCAS again. I'll admit to this one too. A couple of years ago, my lower legs started getting super itchy after showers, and I would pour on the lotion, over and over, and it would do nothing. "What the heck has happened to my skin?" I would wonder. It was histamines, roaming wildly through my body from the hot water and standing up for too long!! The standard ME advice for histamine stuff is:

10mg Loratidine 2x daily (I've just discovered that this can fuck up your stomach and a bunch of other stuff though; see this Twitter thread for alternate antihistamines)

20mg Famotidine 2x

Quercetin daily (I'm doing 1000mg a day)

Some kind of Cromolyn thing. I take a NasalCrom spray a couple times a day, because my sinuses swell up when I lie down (?), which I have to do all the time now. Lol.

Anyway, your sinuses can swell up when you lie down, did you know that? At first it would just happen sometimes, and I would be like why am I suffocating? That's so crazy haha. So I got these things called nasal cones that keep your nasal passages open, and they're just a little bit too big so they slide out all the time, and it's really annoying but other than that they worked. (My brand is Max-Air, the Sinus Relief line.) Then I got reinfected this year, and now my sinuses swell up constantly when I'm lying down. Hence the Cromolyn spray so I can breathe :)

The soft tissues in your face are collapsing: I think this is also an issue for me because it's not like the cones are reaching right up into my sinuses and un-swelling them, right? Anyway other people have reported some really serious issues with eyelids and noses, etc.

Your mouth and nose no longer produce moisture: okay so I got this too, and as a result I must use Ayr brand saline nasal gel multiple times a day, or else it feels like I'm suffocating. I'm pretty sure this Sjogren's Syndrome, another common comorbidity. For me it was one of the first signs something was wrong, circa 2020. Again, I thought pre-diabetes and asked multiple doctors for input and they went "iunno 😐". For the mouth, Xylimelts are your only real choice; don't bother with anything else when it gets to this level. You keep a Xylimelt in your mouth, 24/7, stuck to your teeth, or else you experience the intense, maddening distress of a totally dry mouth. If either of those solutions wears off during the night: don't worry! You'll wake up!!! Don't worry about choking on the Xylimelt, though, it's very safe.

Skin stuff: Dark, flaky patches of skin on the torso, long dark lines around the neck, pruny fingers, skin randomly splitting like paper cuts, chilblains, nails peeling off, other weird stuff.

Swollen genitals: settle down.

[polyabathtub]

Apropos of absolutely nothing (my dash losing its collective shit about the Panthers victory celebrations, me repeatedly seeing videos and going “lol that man is most certainly not drunk”), here’s some info on how one might be able to tell that someone is taking MDMA (aka Molly, ecstasy). The common term for this is rolling*.

Disclaimer: I do not actually know what specific people may or may not have taken, I’m just providing some useful information for my fellow fic writers (fic stands for fiction!) should they decide to write fiction inspired by some of the amazing content we saw last week.

I have heart problems so have never been able to take it myself—but I’m friends with a lot of burners**, and have been blessed with the opportunity to participate in MDMA-fueled cuddle piles. It’s a good time but it can also be dangerous, and it doesn’t mix well with a lot of common medications (particularly antidepressants).

MDMA is a party drug. It makes things like pretty lights and textures more interesting. If you’ve seen “Someone Great” on Netflix, Jenny getting super into textures is a pretty good representation (it’s also one of my favorite movies, but be warned you WILL cry). I couldn’t find a gif within 0.2 seconds of searching so you don’t get one, sorry.

MDMA causes muscle clenching. Taking magnesium helps (magnesium threonate for the brain, magnesium glycinate or bisglycinate are also good for muscle spasms, not too tough on digestion and cheaper). It’s also rough on the brain. Taking something like NAC can reduce risk, but in general MDMA isn’t something that’s safe to do frequently, even if you have a good source and you’re testing your drugs before taking them. I’m not an expert on safe use so I’m not going to give specific recs here, but the people I know who take it research heavily and pregame with supplements.

The other thing that’s key—electrolytes. MDMA messes with electrolyte homeostasis, so it’s important to stay hydrated, and that hydration should be more than just water. If I were, say, a professional athlete celebrating a championship win with Molly, I would probably carry around a bottle of something like pedialyte to sip from (though my personal preference would be a sports-oriented sugar containing supplement like Skratch or LMNT).

MDMA removes your inhibitions to physical contact, particularly with people you’re already positively oriented towards. So, slow dancing with your teammates? Absently groping your teammate’s chest while half paying attention? Literally hanging off of whoever is next to you all night? Molly.

MDMA wrecks pupil reflexes, so anyone taking it who is outside of their natural environment (a dark room with interesting lights) is easily recognizable by their absolutely massive pupils. Or squinting like hell when they hit bright lights***.

MDMA keeps you from sleeping until it wears off. The high lasts 3-6 hours but it’ll probably keep you awake until the morning. Also, when it wears off it often causes molly blues, which might last for a few minutes or hours or sometimes up to a couple of days. Essentially, MDMA floods the brain with serotonin, and when it wears off, it can take some time for things to re-equilibrate.

My point here: I really think there’s a lot of fanfic potential in certain Panthers (Barky) trying this thing for the first time and having an amazing night and then suddenly feeling some big “oh god now that I’ve won it, who do I become?” feelings that <player of your choice> then helps them through.

*for an example of “rolling” in a sentence, see this quote from my recent fic wie viel:

Leon briefly regretted not wearing a hat, or maybe sunglasses, which were fairly effective as a disguise but tended to make people assume he was already rolling—the man wasn’t acting like he’d recognized him, though.

That fic relies on Leon showing up to a private party with a ton of cash (because he’s leaving open the option of buying drugs and also isn’t sure how expensive the party will be) and keeping his face bare (so people won’t assume he’s already set for the night). This conveniently enables the misunderstanding that drives the rest of the plot.

**burners: people who go to Burning Man. This is not a euphemism but it probably could be. If you aren’t sure if any of your friends are burners, don’t worry—they’ll tell you! (I say this with affection, but it is exactly like when your childhood friends got back from summer camp and wouldn’t shut up about it for weeks)

***yes I am thinking of a specific photo of a specific 2-way cat

[lestbian]

do you have migraines or headaches, and are you poor, have shitty/no insurance, doctors who won't listen to you, or just don't want to waste hundreds of dollars on an appointment? well, i went to a neurologist and received this piece of paper which i probably paid way too much for, so you can have it for free.

American Headache Society Complementary and Integrative Medicine Section: Patient Education Kit for Migraine (Recommended Supplements for Migraine Prevention) <- link

the supplements may or may not work, but either way this should save you time and money. you can buy these supplements at most drug stores or online.

below the cut i'm adding a transcript of the pdf in case the link breaks.

stuff my doctor told me:

i should take magnesium glycinate, riboflavin, and CoQ10

magnesium glycinate should be taken at bedtime

didn't recommend feverfew for me, can't remember why

if these supplements don't help, the next step is prescription meds which include Nortriptyline, Topamax, or Emgality

Nortriptyline is an anti-depressant, if you're already on an anti-depressant then don't take this

Topamax is an anti-seizure med also used to prevent migraines. it can make birth control pills less effective

Emgality is administered once a month with a self-administered shot (something like an epi pen). this is what my doctor recommended I take if the supplements don't work. it specifically targets the migraine receptor, so it has very few side effects

PDF transcript:

AHS Complementary and Integrative Medicine Section: Patient Education Kit for Migraine

Recommended Supplements for Migraine Prevention Dietary supplements are commonly used for the prevention of migraine. The recommended supplements have all been studied and found to be effective in the prevention of migraine. If you are pregnant or have other medical conditions, please check with your physician about whether you should take these.

Magnesium

Mechanism: Important in energy production, muscle and nerve function, and may play a role in cortical spreading depression, which is an underlying migraine mechanism.

Evidence: Two large randomized controlled trials found magnesium to be beneficial for migraine prevention.

Dose: 600mg per day. Some people prefer to start at a lower dose to ensure tolerability. Formulations include magnesium oxide, magnesium sulfate, magnesium citrate (better absorbed than oxide or sulfate), and magnesium glycinate (less likely to cause diarrhea than other formulations)

Side effects: May cause soft stools or diarrhea, but could help constipation.

Riboflavin (Vitamin B2)

Mechanism: Involved in mitochondrial energy production, which may play a role in migraine

Evidence: Five clinical trials, including one large randomized controlled trial, have shown positive effect on migraine.

Dose: 400mg per day

Side effects: Turns urine bright yellow/orange and may cause diarrhea.

Feverfew

Mechanism: Parthenolide, the active ingredient, may prevent migraine through its vascular smooth relaxation and anti-inflammatory properties.

Evidence: Four out of six studies showed benefit for migraine prevention

Dose: 50-300mg twice daily

Side effects: Nausea, bloating, and mouth ulcers. Feverfew can cause uterine contractions and is not recommended during pregnancy.

Coenzyme Q10 (CoQ10)

Mechanism: Involved in energy production and helps maintain mitochondrial integrity.

Evidence: Two randomized controlled trials showed benefit over placebo.

Dose: 300mg daily (can be split into 150mg twice a day)

Side effects: Insomnia, fatigue, nausea, or diarrhea.

Other Supplements Butterbur demonstrated benefit for migraine in two large randomized controlled studies; however; preparations may contain pyrrolizidine alkaloids which are toxic to the liver. Due to safety concerns, butterbur was removed from the market in Europe and is currently not recommended. Melatonin and the combination of folic acid/B6/B12 have mixed results for migraine prevention.

Reference: Rajapakse T, Pringsheim T. Nutraceuticals in migraine: A summary of existing guidelines for use. Headache. 2016;56(4).

[meditating-dog-lover]

Things to work on (2024)

1. Continue health goals I achieved this year and build on them (focus on gut health, posture, meet with PT often and to improve some strength and flexibility, etc...). I did a great job this year and I want to continue it!

2. Intermittent fasting 16-8 + walking and supplements.

3. Focus on mental health improvement (ACT focus). I need to work on anxiety, shame, and emotional regulation (and dealing with my mom). Unfortunately, I had a traumatic experience in my last therapy session and had to quit, and am scared of going back to therapy. Magnesium glycinate also helps with anxiety. Another thing that helps is being in touch with your inner child (this has helped me in the past and I'm working on being more in touch as time goes on). More on the last point later.

4. Continue progressing at work, doing more experiments, getting more experience beyond my lab, and looking into being eventually promoted. This is one of my more serious goals.

5. Continue to deposit money to my 401ks, IRA, house savings, and emergency savings, learn how to invest that money, start building credit, and look into real estate and gold investing. This is also one of my more serious goals.

6. Heal any health anxiety and trauma I have (this is trauma-related and not health-related since I did a great job on my physical health this year). I need to stop being anxious whenever I go see doctors and I should take my own health into my own hands.

7. This is more of a physical goal but look into improving my style (and confidence). I always hated clothes and makeup for some reason, so I need to work on this and am even considering meeting with a stylist for some help with this. I already do my hair, nails, eyebrows, skin treatment, teeth whitening, but I hate clothes, makeup, and accessories for some reason. Also keep exercising to stay lean and be able to fit into nice clothes. Looking into colors and styles that flatter me is a good start. I want to get comfortable with clothes and style to the point where I can confidently wear a swimsuit in public (I haven't swam in 5 years and I would love to do it again).

8. Look into hobbies. Inner childhood channeling can help here since I had a lot of hobbies growing up.

9. Read books!!!

10. Get in touch with your inner childhood! I'm on vacation in Cyprus right now and it reminds me of the Middle East from when I lived there as a child in the late 90s early 2000s (without the overwhelming complexities it has now). So if I gain any positive flashbacks from my child while I'm here, I'll write them down.

11. Do more self-care and fun stuff (if this means walking, taking a break, journaling, going to a spa, etc...). I work hard and need to relax and reward my hard work. I am going to do a skin treatment before I travel. I'll think of a list of things that I can do that fall under this category. Sometimes I feel like I don't need these, but once I really do give myself a special treatment I cannot stop thanking myself for doing so. Even if it costs a lot of money, it can be worth it.

12. Continue doing activism (even though this can be very distressing and I will need to learn some emotional regulation here, it's hard to emotionally regulate during a genocide happening right now).

13. Meet with a holistic doctor to address my eczema once and for all.

14. Work on my posture and muscle tightness/flexibility. I have poor posture and it's worth working on it now at a young age before it's too late. I'm going to get a pillow and mattress for my bed, work on my posture at my desk in work, stretch and if needed, get massages.

15. Learn to develop feelings of love and start believing you deserve to be loved. I have a hard time developing feelings for others. If anything my attraction to anyone has been physical lust rather than unconditional love. Again this is another inner childhood thing I want to work on because as a child I used to love unconditionally.

16. Getting rid of any feelings of shame I have. I've been raised to be ashamed and to always be "perfect". My parents were strict and judgemental in this case, despite them being good parents overall. This gets to the point where I feel like I need to hide in a corner whenever I make a mistake and start yelling at myself for being a failure. This will be hard, but it will work out in the end by hook or by crook. This is a self confidence issue. It's also hard knowing I live with my mom who can be super judgy. But I need to address this problem.

Add more if needed...

[nehasharma14]

The Science Behind Magnesium Glycinate for Sleep

Sleep is a fundamental aspect of our overall health and well-being, yet many people struggle with sleep disorders and insomnia. The search for natural remedies to improve sleep quality has led to the exploration of various supplements, including magnesium glycinate. In this comprehensive guide, we will delve into the science behind magnesium glycinate for sleep and explore its potential benefits and mechanisms of action.

What is Magnesium Glycinate?

Magnesium glycinate, also known as magnesium bisglycinate, is a form of magnesium that is bonded with glycine, an amino acid. This unique combination allows for better absorption and bioavailability in the body compared to other forms of magnesium supplements. Magnesium is an essential mineral involved in numerous biochemical processes within the body, including muscle and nerve function, blood glucose control, and energy production. It is also crucial for regulating the sleep-wake cycle.

The Connection Between Magnesium and Sleep

Research has shown a strong connection between magnesium levels in the body and sleep quality. Magnesium plays a vital role in the function of the parasympathetic nervous system, which is responsible for relaxation and promoting a sense of calm. Additionally, magnesium regulates the production of melatonin, a hormone that controls the sleep-wake cycle.

How Magnesium Glycinate Affects Sleep

Relaxation and Stress Reduction: Magnesium glycinate helps relax both the muscles and the mind. Glycine, one of the components of magnesium glycinate, is an inhibitory neurotransmitter that has a calming effect on the central nervous system. This relaxation can ease anxiety and reduce stress, making it easier to fall asleep.

Melatonin Regulation: As mentioned earlier, magnesium is involved in the production of melatonin, the hormone that regulates sleep. Adequate magnesium levels are essential for the body's natural melatonin production, which helps maintain a healthy sleep-wake cycle.

Muscle Relaxation: Magnesium plays a crucial role in muscle function, and its deficiency can lead to muscle cramps and discomfort. By ensuring adequate magnesium levels, magnesium glycinate can help prevent nighttime muscle cramps and promote physical relaxation.

GABA Enhancement: Glycine, found in magnesium glycinate, can also enhance the activity of gamma-aminobutyric acid (GABA), another inhibitory neurotransmitter. GABA helps reduce neuronal excitability, leading to a sense of tranquility and better sleep.

Clinical Evidence

Several studies have examined the impact of magnesium supplementation, including magnesium glycinate, on sleep quality. One randomized, placebo-controlled trial published in the Journal of Research in Medical Sciences found that magnesium supplementation significantly improved sleep duration, sleep efficiency, and sleep onset latency in elderly individuals with insomnia.

Another study published in the journal Nutrients demonstrated that magnesium supplementation improved subjective measures of sleep quality, including sleep time, sleep efficiency, and sleep onset latency, in adults with poor sleep quality.

Dosage and Safety

The recommended dosage of magnesium glycinate for sleep can vary depending on individual needs and circumstances. Generally, a dose of 200-400 mg of magnesium glycinate or three capsules before bedtime is often recommended. However, it's essential to consult with a healthcare professional before starting any new supplement regimen, as individual requirements may differ.

Magnesium glycinate is considered safe for most people when taken at appropriate doses. Side effects are rare but may include gastrointestinal upset in some individuals. People with kidney disorders should consult their healthcare provider before taking magnesium supplements.

Conclusion

Magnesium glycinate is a promising natural remedy for improving sleep quality and managing sleep-related issues. Its unique combination of magnesium and glycine offers potential benefits for relaxation, melatonin regulation, muscle relaxation, and GABA enhancement. While scientific evidence supports its use, it is essential to consult with a healthcare professional to determine the appropriate dosage and ensure it is suitable for your specific needs. Incorporating magnesium glycinate into a comprehensive sleep hygiene routine may be a valuable step towards achieving restful and rejuvenating sleep.

[jim-fetter-illustrations]

We Humans aren't designed to live forever, but we can live longer than we do!

Most “anti-aging” supplements that many popular websites and books recommend do NOT slow down your aging process, they mostly benefit your health as you get older, and you are still ageing at the same rate you always have.

These are substances like vitamin A, vitamin E, coenzyme Q10, lipoic acid, B-vitamins, calcium, omega-3 fatty acids, zinc, multivitamins, curcumin, EGCG, nicotinamide riboside (NR), mushroom extracts and many more are great supplements but they won't slow down your aging!

This means many touted “anti-aging” supplements are nothing more than antioxidants, which do improve your health as you age, like vitamin A, vitamin E, coenzyme Q10, lipoic acid and so on. But they don’t slow down aging. Some antioxidants can even accelerate aging, like lipoic acid or vitamin A and vitamin E.

Ya see,... We human beings aren't supposed to live forever so we have an aging process which triggers (kicks in) at a certain age, and it's downhill from there on. We have a built in fail point, just like automobiles do, so they can keep selling us cars forever.

Ya wanna know what does slow down your ageing process, and they SLOW DOWN not stop it..........

1. "Fisetin", a natural ingredient found in vegetables and fruits, especially in strawberries. Fisetin is mostly known for its senolytic activity, meaning it can clear away senescent cells, ..... zombie cells literally that have done their job biologically but reuse to die off, and are still hanging around sponging off of other healthy cells, like many of our political leaders do.

2. Alpha-ketoglutarate (the calcium form)

Alpha-ketoglutarate (AKG) is a substance that naturally occurs in our bodies. When we get older, the levels of AKG decline. Most studies show in mice that they live 14% longer than mice that didn't take Alpha-ketoglutarate (AKG).

3. Microdosed lithium

Lithium is a mineral found in nature. It seeps from rocks into water, including drinking water, like natural spring water.

Various studies show the more amount of lithium in the drinking water the longer people have been living in that area, and had less neurodegenerative diseases like Alzheimer’s.

So the further you are from the city the better off health wise you are.

Can you see the stars at night,...... if not your still to close to the city!

4. Glycine

Glycine is an amino acid that occurs naturally in our body. When we age, glycine levels decline.

Glycine has many functions in the body. It improves the epigenome (the machinery that determines which genes are switched on or off, a process that goes increasingly awry when we get older). Glycine especially improves the epigenome of mitochondria, the power plants of our cells.

5. Pterostilbene

Pterostilbene is the better brother of the famous anti-aging substance resveratrol.

Resveratrol has long been hyped as a longevity substance. However, it unfortunately did not live up to that hype. Studies showed disappointing results when it came to resveratrol extending lifespan.

6. Malate or malic acid

Malate, also called malic acid, is found in apples, and in our own bodies.

Malate is an important substance in the mitochondria. In fact, malate is a component of the Krebs cycle, which consists of various substances that are chemically modified to provide the energy that keeps all cells going.

7. Magnesium

Magnesium is an indispensable mineral for the body to function properly.

Magnesium helps innumerable enzymes in our body to function properly. Cells shuttle magnesium in and out to propagate nerve signals and to generate muscle impulses, including the beatings of our heart.

Magnesium also sticks to our DNA, stabilizing our DNA, protecting it against damage. Increasing DNA damage is one of the reasons why we get older.

8. Glucosamine (the sulfate form)

Most people know glucosamine as a substance to reduce wear and tear of cartilage and to improve joint health.

Few people know that glucosamine can also extend lifespan in different organisms, including mice.

Studies show that glucosamine is one of the few supplements associated with reduced mortality in humans, and also reduced risk of cardiovascular disease in humans.

9. Hyaluronic acid

Hyaluronic acid is an important component of the skin. But hyaluronic acid (HA) surrounds and embeds many other cells in the body than just the skin cells.

The older we get, the less hyaluronic acid there is in the body. A 70-year-old has only about 19 percent of the amount of hyaluronic acid of a young person.

Studies show that hyaluronic acid, taken orally, can improve skin appearance by reducing wrinkles, improving moisturization of the skin and increasing skin radiance. It can also improve osteoarthritis, which makes sense given joints and cartilage contain a lot of hyaluronic acid.

10. Ginger

Ginger is a well-known spice. But it’s not just any spice, it's THE SPICE for longevity.

Many scientific studies demonstrated multiple beneficial health effects of ginger, like reducing inflammation and protecting cells against damage.

Ginger has been found to extend lifespan in simple organisms, like fruit flies.

Ginger can improve type 2 diabetes and inflammation in humans.

11. Rhodiola rosea

Rhodiola rosea is a very interesting plant that grows in the northern regions of Europa and Asia.

Rhodiola rosea has been used for centuries as an adaptogen, a substance that can improve resilience against both physiological stress and mental stress.

Rhodiola can also improve nerve regeneration.

Studies in humans show that Rhodiola rosea can improve memory, concentration and can reduce fatigue.

12. L-theanine

Theanine is a substance found in green tea, and is one of the reasons why green tea is healthy.

Theanine has been shown to extend lifespan in simple organisms.

Theanine has been associated with healthier blood vessels, and could reduce blood pressure and even obesity.

Theanine has shown to reduce neurodegeneration and protect neurons in the body.

13. Nicotinamide mononucleotide (NMN)

Nicotinamide mononucleotide (NMN) is needed to make NAD+.

NAD+ is a very important substance in the cells. It provides energy for cells and is also a cofactor for proteins that repair and maintain our epigenome and our DNA.

NMN improves metabolism and reduces inflammation.

In conclusion I can say I've studied anti-aging for decades and many anti-aging supplements are based on outdated insights and don’t have any or just very little science backing up their claims.

Also, they do not contain substances that have been shown to act on aging mechanisms.

I personally have been taking 5 of these 13 supplements for a decade, so I should outlive your grandchildren, Lol

I would say if you just took one of these 13 it should be L-Glycine, because Glycine is like the switch that turns on the light in the room, and if the switch doesn't work nothing else gets what it need to illuminate you.

Ginger being a close second to take, which both are fairly cheap in cost to get pharmaceutical grade supplements, and remember only pharmaceutical grade supplements are worth a damn, because Choosing a pharmaceutical-grade supplement is the only way to know for sure that you're giving your body the highest, purest, and most bioavailable form of an ingredient possible, so if it doesn't say "pharmaceutical-grade" on the label, it isn't!!

As Spock from Star Trek would say "Live Long And Prosper", and you do that by knowing how!

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[draintheblood]

Hey!! I’m so sorry about the insomnia thing. I struggled BAD with this for about a year (not continuously thank goodness). It was onset insomnia where I wouldn’t fall asleep until 6-7am. I was exhausted, scared, and desperate.

I’ll relay what ended up helping me. First it’s important to know that my insomnia was a product of extreme anxiety about sleep and exhaustion itself, so all the tips out there about “sleep hygiene” and having a bedtime routine or evening meditation , etc actually made my insomnia worse, because it caused me to obsess too much over the mere concept of sleep and make too big a fuss over the whole process - what should be a natural, easy process when you’re feeling tired, right? Ha, wrong. Brain said no we’re staying awake EXTRA long now.

I relied instead more on distraction, and on reframing the importance I was putting on sleep. All the advice says “stay off your phone!” to get better sleep, but for me having my phone accessible in bed was a godsend to distract me when I would lie down and feel the anxiety and spiraling thought patterns kick up. I’d browse tumblr, or pinterest, read fanfic, and watch ASMR videos - anything that could help keep my mind occupied and not focused on the duality of feeling both exhausted and hyper-awake. This was big for managing it in the moment. Reading a book was also a great thing to do although sometimes hard because it would require turning on the light or sitting up in bed, which frequently felt like too much.

There’s lots of research out there that yells about the “danger” of not getting enough sleep. This definitely contributed to my anxiety. Our bodies are adaptable and resilient. Getting in touch with that deep trust and knowledge is difficult ( esp when the body doesn’t seem to be *cooperating*) but ultimately can make the experience less acutely frightening. Also! There’s research emerging that says that a) we NEED less sleep than we think and b) we often sleep more than we estimate and c) even if you’re lying in bed quietly but awake all night, you’re still getting some valuable rest-induced benefits! That last one was a massive positive discovery and helped me accept my body and mind in the moment and release the intensity of my need for control over how they were both behaving.

Other things that definitely helped over time (not immediately in most cases - it’s okay if it takes a few days or weeks, remember that): magnesium glycinate supplements and magnesium topical lotion/spray before bed, l-theanine throughout the day and evening, phosphatidylserine before bed, getting unfiltered bright morning sunlight each day, using a white noise machine and eye mask. I also found sleep-specific edibles to be really helpful, although I know you mentioned those didn’t work so well for you. It’s highly variable based on formula. I used Kiva brand and that might not be available in your area. They helped take the edge off at night so I couldn’t even get anxious in the first place which is why they worked - so anything similar for you would be a good starting point idea (not alcohol tho - that one screws with your ability to sleep).

Last major thing that helped me was another mindset based shift: I thought about all the days I survived already on slim-to-none sleep, all the things I accomplished and the moments of enjoyment I still was able to have despite the lack of rest and underlying exhaustion. And I reminded myself that I was still capable of living life even without lots of sleep (helps to really think about the times you’ve deliberately chosen to skip out on sleep for really special or fun reasons too! Those count! Those are evidence you can get through it!). Trust your body WILL get the rest it needs, sooner or later. It wants to keep you alive and it’s very VERY good at it in most circumstances, I promise. The brain will catch up to that :) this last tip was super super important, because the sleep anxiety was trying to tell me that I wouldn’t be able to enjoy my life at all ever again if I didn’t sleep. But it was wrong, and I sloooowly started to see that it was lying.

Now I rarely go more than a night at a time missing sleep, and it mainly happens when I get stressed about waking up earlier than usual, or an important event. And I understand where the anxiety comes from so I can gently head it off before I spiral into a true insomnia episode. And even if I do have a bad night - I know I’ll get through the next day, and sleep is coming for me soon. Just know that you can and will recover. I hope hearing my story and ideas helps you even a little bit!!

hi, thank you so so much for sending this. you have no idea how much it means. this hits me really hard because it sound so much exactly like what im going through. its so frustrating and annoying especially to me because im a bit of a perfectionist and control freak and when i cant get my brain and body to cooperate with what i want it makes me so angry and it just adds to the anxiousness. what u said about the sleep hygiene also makes so much sense. i always get so frustrated because its one of the first things i do, and even when the conditions are perfect and i still dont sleep i get so mad that i have to jump through all these hoops that the average person doesnt even have to think about and its still not helping. im also a bit of a pessimist when it comes to behavioral thinking patterns.. like for example i would never be a person who was likely to be able to be hypnotized because my brain just shuts down any suggestions or changes because its so rational that like if i try to change my mindset or do some self hypnosis or whatver another part of my brain quickly takes over and is like "of course this wont work on you because your just trying to trick yourself and this is what you REALLY think". but at the same time i have no control at all over my anxiety or thoughts and it just creates this situation thats such a paradox that it feels like theres no way out. its a vicious cycle where the more i cant sleep the more it takes up more and more of my energy and time. i really appreciate the way you worded this. its gonna take some time to make any of these changes, but i'll definitely try. it feels like my whole life revolves around sleeping and failing to do so (and i hate failing, which just makes everything worse) that if i could just reframe it so that it wasnt such an important, dominating part of my mind i think that would be extremely helpful. thank you so much again for taking the time to message me. its even just inspiring to hear someone in a situation so similar to myself was able to recover and make these changes. ♥️♥️♥️ i hope u have a great holiday season !

[g-kat423]

Today I got vitamin supplements delivered(I was low on my magnesium glycinate, turmeric, and d3 I take daily) I also got these fast chews by vitassium that are supposed to be good for pots they’re fruit punch flavored and have sodium potassium and so on so that’ll be good for me and maybe I can eliminate some of the Gatorade I drink or use the fast chews in addition to them but that’s if I feel they help lol.

I also got some compression wear. I got these zip up toeless knee high compression socks to help with blood pooling in my legs when I stand and such and I also got abdominal compression wear because I also have blood pooling symptoms in my stomach when I’m more active. Gotta love how developing POTS just makes your body forget what it’s supposed to do with your veins when you stand and move. I haven’t really been active today because the weather has been shit on and off and the only real exercise I can manage is walking outside so I’ve just been wearing the compression socks while watching sopranos to see how they feel and they feel pretty good it helps with some of the nerve pain I have in my bad leg from my hip. I also wore the abdominal compression for a bit and it felt nice for a couple hours but then I started to feel uncomfortable. I guess I gotta slowly build up some tolerance and it’s not as though I plan to wear the compression garments 24/7, I mostly want them for when I want to be active because I’ve really been struggling with being symptomatic when I want to walk or need to stand. I’ll probably be taking off the socks shortly too. Other that. That today has been uneventful.

[naturalsupplementonline]

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[thunderheadfred]

Things i have been doing instead of being online (not that being online is bad i just haven’t been here much)

Dealing with the annual resurrection of February: The Worst Month

Throwing everything at the wall to see what will stick re: seasonal depression and delayed sleep phase madness… so far, huge improvement with Even More Rigid sleep hygiene, AM+PM light therapy, magnesium glycinate + melatonin supplements, and some legal low-dose gummies

Researching how to grow cannabis and staring impatiently at our state congress website because thc-isolate gummies can only do so fucking much, man

Grinding for resources in Genshin Impact and gradually learning how to slap enemies with Alhaitham

Cooking just an insane fuckton of Korean food (spicy braised fish, banchan, and rice cakes tonite!)

Also trying to eat all the fruit in the world but always winding up slightly disappointed because it’s the Midwest in winter and the fruit is just blehhh right now (have i mentioned February sucks??) but i just keep trying, you know?

[davidboles]

Top Supplements for Adults Over 50 to Boost Power and Stamina in Kettlebell Training

When you’re over 50 and dedicating yourself to serious Kettlebell training, the right supplements can be a game-changer. They help you maintain energy, recover faster, and keep pushing through those tough workouts. But not all supplements are created equal, and the key is knowing what works best for your body at this stage of life.

Let’s start with creatine monohydrate. This is a staple for anyone looking to boost power and stamina, and it’s backed by decades of research. Creatine helps your body produce ATP, the fuel your muscles need for those intense, explosive movements like swings and snatches. You can start with a loading phase of 20 grams a day for about a week, but many people just stick with a maintenance dose of 3-5 grams daily. The catch? Creatine can pull water into your muscles, so staying hydrated is non-negotiable.

Another great supplement for endurance is beta-alanine. This one helps buffer lactic acid in your muscles, so you can grind through longer sets without that burning fatigue setting in too soon. It’s perfect for those marathon Kettlebell complexes. You’ll want to take 2-5 grams a day. Some people feel a bit of tingling at first—don’t worry, it’s harmless and goes away over time.

Now, let’s talk about omega-3 fatty acids. These are essential for managing inflammation, which is key when you’re hitting the Kettlebells regularly. They also help keep your joints happy and support overall heart health. Aim for 1-3 grams of combined EPA and DHA daily. If you’re taking blood thinners, it’s worth checking with your doctor since omega-3s can have a mild blood-thinning effect.

For bone health and muscle function, vitamin D3 paired with K2 is a must. As you age, keeping your bones strong becomes crucial, especially with the dynamic movements Kettlebell training involves. Vitamin D helps with calcium absorption, while K2 makes sure the calcium goes to your bones, not your arteries. A dose of 2000-5000 IU of D3 and 100-200 mcg of K2 daily is a solid starting point.

Magnesium is another powerhouse, especially for recovery. It helps with muscle relaxation, reduces cramps, and improves sleep—an often overlooked aspect of recovery. You’ll want to take 300-400 mg daily, ideally as magnesium glycinate or citrate for better absorption. Just be careful, as high doses can cause some stomach upset.

If you need an extra boost in blood flow and endurance, L-citrulline is worth a look. It increases nitric oxide production, improving circulation and delivering more oxygen to your muscles. This is a game-changer for high-rep Kettlebell sets. Take 6-8 grams about 30 minutes before training.

Oh, and let’s not forget protein powder. Recovery and muscle maintenance hinge on getting enough protein, and a shake can make hitting your daily targets much easier. After a workout, 20-30 grams of a high-quality plant-based protein is ideal. You should aim for 1.2-1.6 grams of protein per kilogram of body weight daily.

All these supplements are tools to help you thrive in your training. They’re not magic bells, but when used smartly and consistently, they can make a big difference. Remember, the foundation is always a balanced diet, quality sleep, and a well-structured training program. Supplements fill in the gaps and give you that extra edge to keep swinging, snatching, and pressing your way to better health.

[kidneycop]

Natural Supplements For Kidney Stones

Kidney stones are a painful condition that affects millions worldwide. While prescription medication is often used to treat and prevent stones, natural supplements can also provide relief. This article will explore some of the best herbal and dietary supplements for different types of kidney stones like calcium oxalate stones. Read on to learn natural ways to keep your kidneys stone-free and pain-free.

Best Supplements for Calcium Oxalate Stones

Calcium oxalate stones are the most common type, forming when too much calcium and oxalate collect in the urine. Best supplements for calcium oxalate stones for preventing and treating stones:

Citrus Fruits and Juices

Citrus fruits like oranges, grapefruits, and lemons are good sources of citrate, which attaches to calcium in the urine to help prevent stones from forming. Drink fresh citrus juices as part of a well-hydrated diet. The citrate can help dissolve small calcium oxalate crystals before they get bigger. Citrus fruits make for a tasty supplement.

Water is key for flushing out stones

Most experts recommend drinking at least ten 8-ounce glasses daily to steadily dilute and wash out the urine. For those with a history of stones, an even higher fluid intake of 12–14 glasses may be advisable. Being well hydrated promotes urinary output of around 2 litres each day which reduces the likelihood of crystal/stone formation. Even increasing water by just 1–2 glasses extra can slash risk significantly.

Magnesium is an unsung hero

Taking a magnesium supplement may help reduce the risk of recurrent calcium oxalate stones by competing with calcium absorption in the gut and increasing citrate levels in the urine. Magnesium is also needed to metabolize and flush out oxalate from the body. Opt for a chelated form like magnesium glycinate for maximum absorption.

Vitamin B6

Vitamin B6, also known as pyridoxine, assists the liver in producing citrate to bind with calcium in the urine and reduce stone risks. A daily 25–50 mg supplement provides the recommended amount. B6 is non-toxic even at higher doses. Combined with citrus and magnesium, B6 supports urinary properties that hinder stone growth.

Also Read: Are Carrots and Cilantro Good for Your Kidneys?

Kidney Stone Treatment and Prevention

Natural kidney stone treatment focuses on dissolving any existing stones while long-term prevention maintains a stone-free state. Here are some top supplements:

Dandelion Leaf

Studies show dandelion leaf extract helps treat and prevent calcium kidney stones. The bitters stimulate bile flow and liver function to promote healthy digestion and metabolism. The potassium content balances sodium levels while diuretic properties flush out minerals through urine. It’s a gentle yet effective herbal remedy.

Plant Silica

Colloidal plant silica from horsetail and bamboo contains beneficial silicic acid to strengthen connective tissues in the kidneys and throughout the body. Some research indicates silica may also inhibit stone formation by binding excess minerals in urine before crystal buildup. It supports overall kidney and urinary tract health.

Oxalate-Blocking Probiotics

Certain probiotic strains like Lactobacillus acidophilus and Lactobacillus plantarum help break down and eliminate oxalate in the gut before it’s absorbed. This reduces urinary oxalate levels linked to stone risk. Look for broad-spectrum probiotic supplements, or dietary sources of active cultures like yogurt, kimchi, and kefir.

Conclusion

Approaches towards kidney stone prevention and treatment have been shown to be very effective because they include dietary modifications along with enough amounts of water intake and the use of natural supplements based on the type of kidney stones. Compounds such as water, magnesium, lemon balm, citrus fruits, probiotics, and vitamin B6 are able to adjust the concentration of minerals that promote the formation of stones in the body.

Are recurring kidney stones stressing your body and budget? Kidney COP tailors organic supplement packs to your individual biochemistry, giving your kidneys the daily backup they deserve. Our dedicated advisors make kidney health attainable — inquire now to rid yourself of stones safely and for good.

[meditating-dog-lover]

Supplements I take

multivitamin

5000 IU D3 + K2

digestive enzymes + 1 billion CFU probiotics

sometimes I drink aloe juice for gut health (not really a supplement)

not really a supplement but flax oil for the omega 3

magnesium glycinate

I was taking a DIM detox supplement which helped with liver and hormone health, but I quit because it has milk thistle and I want to minimize allergens. Once I start my allergy shots I feel like I can take it again (I'm allergic to ragweed).

Reverse osmosis water has been a good thing I've implemented in my daily routine. Also not a supplement, but it helps because I'm drinking cleaner water.

Drinking water has fluoride in it. My dentist told me fluoride is safe on the teeth, but drinking water is overfluoridated. Too much fluoride in the body can disrupt iodine absorption which can negatively affect the thyroid. Also it can lead to increased aluminum absorption which can reduce dietary phosphorus absorption, therefore causing more harm to teeth (teeth need phosphorus arguably more than fluoride). However I don't believe it's a toxin, especially not in toothpaste, really anything is a toxin in large amounts. So I'll stick to fluoridated toothpaste but RO water for this reason. I'm not anti-fluoride and a lot of non-fluoridated toothpastes don't have any mineralizing agents which won't strengthen teeth. Based on my dentist's recommendation I would stick to fluoridated toothpaste and nonfluoridated water. I also use both a fluoride toothpaste and a nano-hydroxyapatite toothpaste. In a perfect world I would find a toothpaste that contains both. I found one on Amazon but it's 22$ for a tube which is expensive.

I'll see a dentist with my mom once I get my skin under control (January or February since I'll be due for an appointment then).

I also take antihistamine, antianxiety, and antidepressant medication.

As a woman I do want something for hormone support, and even liver support. So the DIM detox is a great supplement. It's just expensive and I don't want to take a bunch of things either. Chlorella and spirulina are good for removing toxins from the body, including heavy metals. But they both taste like awful fishy grass.

I wish my enzyme supplement had more probiotic CFUs. And I don't want to get a separate supplement because I don't want to take too many supplements.

So liver and hormone and microbiome support are things I can look into in the future. I'll tell my obgyn I'm taking a break from the DIM Detox supplement.

I have blood work on Monday to check for my hormones and insulin response. I want to be metabolically healthy (I am for the most part but some minor improvement won't hurt).

[amaranthnymph]

How long have you been doing the holy grail of cum? I've been at for about two weeks and haven't noticed any difference tbh 😔

Uuuuh, I think it’s been about two weeks for me too? I should’ve written down the date I started lol If you haven’t noticed a difference, you might wanna tweak the dosage of some of the supplements. For those interested in the original stack:

The Cum Holy Grail

(1) L-Arginine, 1000mg

(2) Zinc, 50mg

(3) Pygeum, 200mg

(4) Lecithin, 1200mg

This is what I’m taking so far:

The Cum Holy Grail ‧₊˚❀༉‧₊˚. Ama Edition ‧₊˚❀༉‧₊˚.

(1) L-Arginine, 6000mg

(2) Zinc, 50mg

(3) Pygeum, 1500mg

(4) Lecithin, 2400mg

(5) Magnesium glycinate, 600mg

I plan on adding horny goat weed and maybe L-DOPA to my stack, but the most important thing is to STAY HYDRATED. Even without the supplements, drinking a lot of water (but not to the point of water poisoning, of course) is enough to increase volume by a lot. You should also skip the zinc once or twice a week as some people experience flu-like symptoms if they have too much zinc, tho I haven’t had that issue at all (I’m guessing I’m zinc deficient?).

[purehealthpulse]

A Restful Revolution: My Experience with Magnesium Breakthrough

Let's face it, life in the modern world can be draining. Between work deadlines, social commitments, and the constant blue light exposure from our devices, it's easy to feel depleted and out of sorts. In search of a natural solution to combat fatigue and improve sleep, I decided to try Magnesium Breakthrough. Here's how these capsules have become a game-changer for my overall well-being.

A Symphony of Seven Magnesiums

One of the things that initially drew me to Magnesium Breakthrough was its comprehensive formula. Unlike many magnesium supplements that contain just one or two types, this one boasts a unique blend of seven different magnesium forms. This includes well-known varieties like magnesium glycinate, known for its gentle absorption, and magnesium citrate, which promotes regularity. Having this variety ensures that my body can absorb the magnesium it needs in the most effective way.

Easy to Swallow, Easy to Integrate

Taking Magnesium Breakthrough couldn't be easier. The capsules are a comfortable size and go down smoothly with a glass of water. The recommended dosage is just two capsules a day, which I typically take in the evening before bed. This simple routine has made it effortless to integrate Magnesium Breakthrough into my daily schedule – no complicated multi-dose regimens here!

A Gradual Shift Towards Restfulness

It's important to note that Magnesium Breakthrough isn't a magic sleep potion that instantly lulls you off to dreamland. However, I've noticed a gradual shift in my overall sleep quality since taking it. Those familiar feelings of pre-sleep anxiety seem to have lessened, allowing me to fall asleep more easily. More importantly, I wake up feeling more refreshed and ready to tackle the day. No more groggy mornings or that dreaded "afternoon slump."

Improved Energy Levels and Overall Wellbeing

An unexpected benefit of taking Magnesium Breakthrough has been an improvement in my energy levels throughout the day. Previously, I often felt sluggish and drained, especially in the afternoons. Since taking the supplement, I have more sustained energy throughout the day, allowing me to be more productive and engaged in my activities. This overall improvement in well-being has had a positive impact on all aspects of my life, from my work to my social life.

A Natural Choice for a Balanced Life

Overall, I'm very impressed with Magnesium Breakthrough. It's a comprehensive and easy-to-use supplement that has made a noticeable difference in my sleep quality, energy levels, and overall well-being. The focus on natural ingredients and the variety of magnesium forms make it a more appealing option compared to some of the harsher sleep aids on the market.

A Worthy Investment in Rest and Rejuvenation

While there's an initial investment involved, the long-term benefits of Magnesium Breakthrough make it a worthwhile purchase. After all, a good night's sleep and a boost in energy are priceless! If you're looking for a natural way to improve your sleep, increase your energy levels, and promote overall well-being, I highly recommend giving Magnesium Breakthrough a try. Remember, it's always best to consult with your doctor before starting any new supplements, especially if you have any pre-existing health conditions.