#future of insulin

[edairy]

Diabetes around the world, the IDF Diabetes Atlas (2021) reports that 537 million adults approx. of the age 20-79 years are suffering from diabetes. By the year 2045, 1 out of 8 adults will be a diabetic patient. Furthermore, 3 out of 4 adults suffering from diabetes live in low-income countries. From this report, we can get an idea, of how difficult diabetes will be in the future to manage.

Let’s understand what diabetes is actually. A person suffering from diabetes, cannot properly produce insulin, required to control the blood sugar level of the body. Insulin is a boon for diabetes treatment, it makes a deadly disease, manageable.

[oatsynalliums]

Hello this a long shot call, am Naom Abdulhaq a citizen of Palestine. I am here to request for your support to help get my insulin (Humalog), just an injection for today to save my life please I beg.I was diagnosized with type 1 diabetes and due to current situation in Gaza I'm unable to get my insulin injection as a result I'm here begging for little financial support to help me purchase insulin for this week. Am sorry if am sending you again this request, kindly donate any amount please. My donation link is in my pinned post🇵🇸. Thank you and be blessed ❤️

.

[candorverity]

Leaking insulin, as you do

[vamptastic]

ok so. nobody who says i want to be able to eat a banana year round in the utopian future is saying they also want someone living a shit life to pick it for them. it's not the hill i'd die on but what they're saying is they don't want a downgrade to their quality of life. they usually have a quality of life that i think we can all agree is reasonable to want. why bother trying to constantly tell people they should actually want to virtuously suffer for other people's sake when the real goal is in fact for nobody to suffer At All.

[wanderingandfound]

My dad works for the private sector and has been on call my entire life. My mom works for the public sector and can usually take time off when needed. My dad has made the bulk of the household money, and also had really good health insurance with vision and dental. From the ages of 8 to 26 I got glasses every year until I aged out of it.

Anyways, my dad was pressured to retire early. He has still probably worked his way to an early grave but like, hopefully he'll be alive longer than he would have if he had been able to keep to his plan of retiring at 70.

So my dad and sister are going to my mom's health insurance. The benefits at government jobs are supposed to be ""good"". My mom now needs to figure out how to pay $900 more each month. And it wasn't like what they were already paying was cheap.

Anyways, health insurance shouldn't exist and I never want to work a job that can call me at all hours of the night and on any vacation I may plan. Even if that health insurance did approve my medicine over a year quicker than Medicaid.

[eevyerndracaneon]

.

[starkitten101]

Both my father and paternal grandfather have/had type 2 diabetes, so I got curious and did some googling to see if Indians in general are more prone to it

and

well

I’m fucked :/

[lastoneout]

I keep thinking about all of the disabled activists and people before me who stranded themselves on the 4th floor of buildings for weeks and crawled up stairs and fought with airline staff and schools and doctors and refused to stop existing in the face of injustice and bigotry no matter how big and scary and hopeless it seemed. Every time I get angry and scared the protests that lead to the creation of the ADA pop up again and remind me that disabled people are so much fucking stronger than anyone has ever given us credit for, and I can't help but be proud of that. And I know not all disabled people feel like we should take pride in our disabilities and have flags or whatever, but I think not just living, but thriving, in spite of a world that wants us dead and gone, in the face of both illness and persecution, and how we've not only bought ourselves forward, but uplifted the disabled people around us, secured more equal futures for everyone who will come after, and truly changed the way so many abled people have seen us for the better is something to be damn fucking proud of.

We have always been here and we always will be, there will never be a world without disabled people because being disabled is not bad, it's a natural part of the human experience and yeah it sucks some times but even when it sucks we have fought to build beautiful, unique, happy lives with people, both like us and not, and that should be celebrated.

The first sign of human civilization is the healed femur. The body of the profoundly disabled person who would have needed help to even just eat being carefully laid to rest after decades of a full, happy life. The medicinal plants showing even before we were entirely human we were doing what we could to not just survive, but alleviate suffering while we're at it. Above everything, evolution selected not the baby who can walk and eat and be quiet, but the one that can ask for help.

Disabled people are not just angry cockroach motherfuckers who refuse to die, we are proof of humanity's HUMANITY. Proof that natural selection selected a species that takes care of each other. From healed femurs and medicinal plants to vaccines and IVs and insulin to now, we are driven to help one another, we are at our strongest when we don't leave our most vulnerable behind. And I am living proof of that. My mother is living proof of that. Every disabled and chronically and/or mentally ill person I know is living proof of that.

And I don't know about the rest of you, but will carry that shred of humanity's true nature inside me like it's my fucking soul. I am scared and angry and hurt, but I have a lifetime's experience being scared and angry, and I can shake off the kind of pain that would make Atlas crumble to dust like it's nothing but a stiff fucking breeze. Disabled people have always been here, turning fear and anger and pain into joy and beauty and connection, and I'm not going to let everyone who came before me down. I'm not going to give up. Not now, not ever.

It's okay if you're disabled and you've hit your limit, you're too scared and tired and hurt, I won't blame you. But I won't abandon you, either. I might not be able to right all of the wrongs in the world, but I'll be strong, I'll carry all of you with me, I will not give up.

As I've said before, society hates a cripple who won't die, so we must spite them and live anyway.

Please, live anyway. I know if anyone can, it's us.

[rodentblood]

regarding last reblog I literally was just talking about this type of issue in stream yesterday

I'm getting a new insulin pump and my doctor was talking up this new one available through the same company as my current pump. Works exactly the same and can connect with the continuous glucose monitor I'm already on, etc, etc but she then drops the bomb that it can ONLY be used by downloading an app on my phone and controlling it that way.

There's no screen on the device, there's no buttons NOTHING you have to have a smartphone to be able to use it. So I instantly told her no.

I am not having a life saving medical device locked behind my fucking phone?? What if I lose my phone? What if I break it? What if I forget to charge my phone? What if I get into a situation where I break my phone and can't afford a new one for a while? There's so much shit that can happen that would resort in me not having access to my insulin it's ridiculous that there's just nothing aside from an app that functions with the device imo

Give me the option to choose a smart phone app but don't make it mandatory And I refuse to budge on this, don't care if I sound old. It's ridiculous how much people rely on their phones for stuff and for something as important as this? Nuh uh sticking on device screens and buttons thank you very much

[forcebookish]

lmao is every cgw episode going to start with a preview of fuyu doing something fucked up to itsuki snskkd

[lets-steal-an-archive]

By Bernie Sanders | July 13, 2024

I will do all that I can to see that President Biden is re-elected. Why? Despite my disagreements with him on particular issues, he has been the most effective president in the modern history of our country and is the strongest candidate to defeat Donald Trump — a demagogue and pathological liar. It’s time to learn a lesson from the progressive and centrist forces in France who, despite profound political differences, came together this week to soundly defeat right-wing extremism.

I strongly disagree with Mr. Biden on the question of U.S. support for Israel’s horrific war against the Palestinian people. The United States should not provide Benjamin Netanyahu’s right-wing extremist government with another nickel as it continues to create one of the worst humanitarian disasters in modern history.

I strongly disagree with the president’s belief that the Affordable Care Act, as useful as it has been, will ever address America’s health care crisis. Our health care system is broken, dysfunctional and wildly expensive and needs to be replaced with a “Medicare for all” single-payer system. Health care is a human right.

And those are not my only disagreements with Mr. Biden.

But for over two weeks now, the corporate media has obsessively focused on the June presidential debate and the cognitive capabilities of a man who has, perhaps, the most difficult and stressful job in the world. The media has frantically searched for every living human being who no longer supports the president or any neurologist who wants to appear on TV. Unfortunately, too many Democrats have joined that circular firing squad.

Yes. I know: Mr. Biden is old, is prone to gaffes, walks stiffly and had a disastrous debate with Mr. Trump. But this I also know: A presidential election is not an entertainment contest. It does not begin or end with a 90-minute debate.

Enough! Mr. Biden may not be the ideal candidate, but he will be the candidate and should be the candidate. And with an effective campaign taht speaks to the needs of working families, he will not only defeat Mr. Trump but beat him badly. It’s time for Democrats to stop the bickering and nit-picking.

I understand that some Democrats get nervous about having to explain the president’s gaffes and misspeaking names. But unlike the Republicans, they do not have to explain away a candidate who now has 34 felony convictions and faces charges that could lead to dozens of additional convictions, who has been hit with a $5 million judgment after he was found liable in a sexual abuse case, who has been involved in more than 4,000 lawsuits, who has repeatedly gone bankrupt and who has told thousands of documented lies and falsehoods.

Supporters of Mr. Biden can speak proudly about a good and decent Democratic president with a record of real accomplishment. The Biden administration, as a result of the American Rescue Plan, helped rebuild the economy during the pandemic far faster than economists thought possible. At a time when people were terrified about the future, the president and those of us who supported him in Congress put Americans back to work, provided cash benefits to desperate parents and protected small businesses, hospitals, schools and child care centers.

After decades of talk about our crumbling roads, bridges and water systems, we put more money into rebuilding America’s infrastructure than ever before — which is projected to create millions of well-paying jobs. And we did not stop there. We made the largest-ever investment in climate action to save the planet. We canceled student debt for nearly five million financially strapped Americans. We cut prices for insulin and asthma inhalers, capped out-of-pocket costs for prescription drugs and got free vaccines to the American people. We battled to defend women’s rights in the face of moves by Trump-appointed jurists to roll back reproductive freedom and deny women the right to control their own bodies.

So, yes, Mr. Biden has a record to run on. A strong record. But he and his supporters should never suggest that what’s been accomplished is sufficient. To win the election, the president must do more than just defend his excellent record. He needs to propose and fight for a bold agenda that speaks to the needs of the vast majority of our people — the working families of this country, the people who have been left behind for far too long.

At a time when the billionaires have never had it so good and when the United States is experiencing virtually unprecedented income and wealth inequality, over 60 percent of Americans live paycheck to paycheck, real weekly wages for the average worker have not risen in over 50 years, 25 percent of seniors live each year on $15,000 or less, we have a higher rate of childhood poverty than almost any other major country, and housing is becoming more and more unaffordable — among other crises.

This is the wealthiest country in the history of the world. We can do better. We must do better. Joe Biden knows that. Donald Trump does not. Joe Biden wants to tax the rich so that we can fund the needs of working families, the elderly, the children, the sick and the poor. Donald Trump wants to cut taxes for the billionaire class. Joe Biden wants to expand Social Security benefits. Donald Trump and his friends want to weaken Social Security. Joe Biden wants to make it easier for workers to form unions and collectively bargain for better wages and benefits. Donald Trump wants to let multinational corporations get away with exploiting workers and ripping off consumers. Joe Biden respects democracy. Donald Trump attacks it.

This election offers a stark choice on issue after issue. If Mr. Biden and his supporters focus on these issues — and refuse to be divided and distracted — the president will rally working families to his side in the industrial Midwest swing states and elsewhere and win the November election. And let me say this as emphatically as I can: For the sake of our kids and future generations, he must win.

Bernie Sanders is the senior senator from Vermont.

[crippled-peeper]

thank you medical technology for giving me a dad that’s still alive and for prolonging his life and for prolonging MY life and for all the times I’ve never caught a disease I’m vaccinated for and all the times doctors had to cut me open to fix my insides and I was able to sleep through it thank you anesthesiologists thank you surgeons thank you physical therapists thank you nurses thank you nurse practitioners thank you surgery technicians thank you neurologists thank you cardiologists thank you gastroenterologists thank you ENT doctors thank you OB/GYNs thank you midwifes thank you scientists who discover and synthesize new medicines thank you engineers designing prosthetics and insulin pumps and metal implants thank you janitors for keeping our hospital rooms and hallways clean and safe thank you phlebotomists thank you laboratory workers thank you pharmacists for filling our meds THANK YOU MODERN MEDICINE FOR MY LIFE AND FOR MY FAMILY AND MY FUTURE

[reasonsforhope]

"People living with diabetes might have a new hope. Scientists have tested a new drug therapy in diabetic mice, and found that it boosted insulin-producing cells by 700% over three months, effectively reversing their disease.

Beta cells in the pancreas have the important job of producing insulin in response to blood sugar levels, but a hallmark of diabetes is that these cells are either destroyed or can’t produce enough insulin. The most common treatment is regular injections of insulin to manage blood sugar levels.

But a recent avenue of research has involved restoring the function of these beta cells. In some cases that’s started with stem cells being coaxed into new beta cells, which are then transplanted into patients with diabetes. Researchers behind this kind of work have described it as a “functional diabetes cure.”

Now, scientists at Mount Sinai and City of Hope have demonstrated a new breakthrough. Previous studies have mostly involved growing new beta cells in a lab dish, then transplanting them into mice or a small device in humans. But this new study has been able to grow the insulin-producing cells right there in the body, in a matter of months.

The therapy involved a combination of two drugs: one is harmine, a natural molecule found in certain plants, which works to inhibit an enzyme called DYRK1A found in beta cells. The second is a GLP1 receptor agonist. The latter is a class of diabetes drug that includes Ozempic, which is gaining attention lately for its side effect of weight loss.

The researchers tested the therapy in mouse models of type 1 and 2 diabetes. First they implanted a small amount of human beta cells into the mice, then treated them with harmine and GLP1 receptor agonists. Sure enough, the beta cells increased in number by 700% within three months of the treatment. The signs of the disease quickly reversed, and stayed that way even a month after stopping the treatment.

“This is the first time scientists have developed a drug treatment that is proven to increase adult human beta cell numbers in vivo,” said Dr. Adolfo Garcia-Ocaña, corresponding author of the study. “This research brings hope for the use of future regenerative therapies to potentially treat the hundreds of millions of people with diabetes.”

The results are intriguing, but of course being an animal study means there’s still much more work to be done before it could find clinical use. So far, harmine alone has recently undergone a phase 1 clinical trial in humans to test its safety and tolerability, while other DYRK1A inhibitors are planned for trials in humans next year.

Perhaps most importantly, the team will soon experiment with combining beta-cell-regenerating drugs with others that modulate the immune system. Ideally this should help overcome a major hurdle: the immune system will continue attacking new beta cells as they’re produced.

The research was published in the journal Science Translational Medicine."

-via New Atlas, July 14, 2024

[catiuskaa]

missed me, missed me, now you gotta...

SUMMARY: minho wasn’t grumpy, nor he was jealous. but he hasn’t been the same ever since he fell in love with you.

REQUESTED! by a sweet annonie right here. pookie, your idea was lovely to write! lil grumpy minho, im melting… it’s a bit short, but I hope you like it! <3

CW: use of (crack) text messages to convey the plot, starring: han quokka as cupid + reader’s bsf, clingy minho as king of my heart, and ngl, type 1 diabetes fluff ahead. keep insulin shots close just in case! lol

WC: 1.1k

A/N: i love how i’m slowly turning into a minho blog/page lmaoo, only minho: the man, the myth, the legend!

[🪻☆🌫️☆🪻]

The same ringtone buzzed again during rehearsals. Its ding had sounded so many times already that it had started to get repetitive really quickly.

Minho frowned as he looked in the mirror, retouching his rolled sleeves just once more for what he secretly knew it had been more than twenty times. In the span of ten minutes. Maybe even less.

But Minho wasn’t ‘grumpy’.

He so wasn’t.

His day had been normal so far. He had no reason to be grumpy. Not one what-so-ever.

He had woken up in between your arms, and even if he had ‘complained’ about it, he loved being the little spoon. And also, his cats jumped on the bed and, just for once, none of them landed on his face.

There had been just one thing.

…

Well. Technically more than one.

You had rushed outside this morning. You claimed you didn’t have time to have breakfast with him, because you were late for something he didn’t really get. Because of that, you hadn’t come over to the JYP building with him. He had to drive over alone. And you hadn’t pecked him goodbye at the entrance like always.

But he. Wasn’t. Grumpy.

Not. At. All.

> sunggie: girl, did you hide his cats or smth?

< minho’s owner: lol, wdym dude?

> sunggie: he looks like he’s going to kill me.

> sunggie: And he loves me! Wtf??

“Jisung-ah.”

Han shrieked in his place in the sofa, his phone almost falling off his hands. He quickly turned it off, hoping that the grumpy dancer hadn’t seen the old or new messages.

“Who were you texting?” Minho frowned, deeper this time.

“Oh.” Jisung chuckled. “Just checking in on noona.”

“My girlfriend?” The way Minho enunciated the title felt a bit possesive. Jisung eyed at him weirdly for a second. Even he felt weird himself.

Jisung nodded sheepishly, turning his phone back on but quickly opening a random app.

“Yeah. I owed her a call back.” He shrugged, nonchalantly accepting that he had opened Subway Surfers, and started to play.

As the catchy music came from Han’s phone, Minho shook his head.

Not grumpy.

Not at all.

But the thought that you had been texting Han and didn’t text him —instead of him— did funny things in his chest.

Now, keep in mind that Minho would never describe himself as a jealous man.

He trusted you with his cats, of course he trusted you regarding your relationship. But he had barely got a hold of you all day. And Han had. By call and text. Like he was doing now.

Not grumpy.

Sure.

< minho’s owner: you dead yet?

Jisung groaned.

> sunggie: no! you made me lose my score!

> sunggie: and I don’t have any keys! ㅠㅠ

< minho’s owner: sucks to suck, lol

< minho’s owner: but what’s wrong with my future husband? did you do something?

> sunggie: he’s moody since he came in this morning.

> sunggie: you weren’t here tho. smth wrong between ya?

< minho’s owner: no…? just had to run to work early…

And then, something in Jisung’s paboracha brain connected. Probably because of how he had named your contact in his phone.

> sunggie: omg

< minho’s owner: what?

> sunggie: that corny dumbass

> sunggie: he’s so stupid

< minho’s owner: bitch what is it???

> sunggie: he’s moody bc u didn’t come in with him today!

You hesitated. Could that be it?

< minho’s owner: really? u think so?

> sunggie: bitch I know so!

> sunggie: imma go get boba for the boys, get your ass here and come w/ me

Jisung’s brain started to work at cupid’s speed.

< minho’s owner: omw. be there in 5’

“Guys, I’m gonna go get boba. Do any of you want something?”

The rest of the gang blabbered something while some kept going over the steps of the choreography and the others rested on the couch, doozing off or on their phones. Han quickly noted down everyone’s orders, not before being squinted down by Minho. He held back a shiver.

“Clingy prick…” Jisung mumbled, leaving quickly.

He walked out of the JYP building, waiving and half bowing to the staff members and other artists in the building.

< minho’s owner: just parked! ^^

Jisung entered the boba place next to the building, smiling at the cashier as he read down the orders on his note app, and stood aside, waiting for the drinks.

“Hey!” You smiled widely at him, taking off your scarf, merely leaving it hanging on your shoulders. He clapped your hand, playfully slapping your back.

“Working hard?” Jisung snickered, pointing at the bag on your other hand.

You side-eyed at him, giggling softly.

“Took some snacks before heading off.” You shrugged. “We can sneak these in, right?”

Jisung scratched the back of his neck. “We’ll… come up with something.”

You both struggled carrying the drinks, teasing each other and betting who’d make a mess first. But all giggles came to an end when the security guard stared at you.

“Name and business?” He asked in a low huff.

Your body stiffened.

“She’s my sister,” Han chimed back. You were in fact far from being his sister, but that didn’t matter when the guard seemed to nod. “She’s just helping me carry the drinks inside.”

“And the bag? What’s inside?”

You cleared your throat, smiling. “Clothes for him to change once he finishes training.” You lied.

Thank God for his imagination. And for his stupid idea of shoving your scarf and his hoodie into the bag of snacks.

“Ok. You may come in.” The guard smiled politely.

Only after the both of you had gotten into the elevator you allowed yourselves to let out a sight full of relief. You two then smirked, high-fiving.

“Thank you, bro.” You teased in a snicker.

He cackled. “You’re welcome, sis.”

You both laughed and joked until you reached the training room.

“The person you dream of is back!” Han cackled.

“Noona!” Felix grinned happily.

“Yeah, that’s me!” You cackled at Jisung’s faked frown.

You smiled and greeted everyone as you entered, leaving a certain bunny boy for last.

You sat next to him on the couch, and without missing a beat, he took your legs and layed them on his lap.

You took a sip of his drink, and he stared at you, almost with a squint.

“You’ve made me jealous of fucking Han Jisung.” He stated matter-o-factly, making you practically choke on the tapioka pearls.

You coughed. “What?”

“You texted him all evening. And me? Not even a good luck kiss this morning.”

“Aw, are you grumpy, kitten?” You grinned teasingly, speaking only towards him in a soft tone to his ear. You pecked his cheek.

He needed more of those.

Grumpy, huh?

“Yes. Very.” He mumbled, hiding his blushed and pleased grin in the crook of your neck. “Need more kisses.”

“Well, you know how it goes.” You mumbled in a snicker. He hummed at you, waiting for you to explain.

You kissed his forehead softly, his hands stroking your thighs.

“Missed me, missed me, now you gotta kiss me.”

~Kats, who can write this in one sit, but can’t figure out how chemistry works (yes have exams, why did I choose this for myself, help)

[kyri45]

I'm making this post since there's an italian idiom "a Natale, siamo tutti più buoni" (during Christmas, we are all more good) and while I prefer to keep this blog for only my art, today is a day where most of us can do something good, even if small.

If you, just like me and many lucky others, are able to spend this Christmas at home, with warm food and a place to call home, please take a moment to help, spread awareness, or even just think about those who can't.

These are some sources I wish just to spread, because I know it can be overwhelming to wanting to help in some ways, but don't know how or who, or even if the source asking is attendible.

el-shab-hussein and nabulsi's spreadsheet is, I think the most known one for vetted fundraisers.

gazafunds.com has one highlighted campaign you can donate to if you don't know which one you should or want donate to.

Operation Olive Branch’s spreadsheet also has other links with alternative ways to help, including donating directly to the municipality, to family shops, and other resources as well.

Here's some of the people (listed) that you can help today:

@suad-khaled (line 279) gofund

"Can you imagine being stripped of safety at the happiest moment of your life? I’m Suad, a young mother from Gaza, where I gave birth to my son Khaled amidst the chaos of w@r. I urgently need your support to secure shelter and medical care for Khaled. You can be part of our story, as every bit of help makes a real difference."

Suad Alkurdi (line 55) gofund

"My name is Souad Al-Kurdi, I am 32 years old, from northern Gaza. I have three children, Wissam, Karim, and Adam. My husband is diabetic and does not take insulin doses and treatment due to their lack of availability in Gaza. My children suffer from diseases due to pollution and malnutrition. We need money to travel to Egypt and build the future of our children there. Travel requires $9,000 per person, and this needs your support."

Jehad Abuhamda's relatives (line 137) gofund

Hello, my name is Jehad Abuhamda. I’m an American/ Palestinian who is seeking for your support in helping me get my close relatives out into safety. My relative lived a hard life after having is right hand amputated from the remnants of Israeli explosives in a previous war. Despite that, it did not hinder him from working in order to provide for his family. But now that he has lost his home, and with the worsening living conditions, He has decided that it is best to leave for the sake of his children.

Of course, be sure to check your local organizations to help those in need of shelter and food, especially if you live in a very cold area!

And remember that if you can't donate, you can always share AND boycott!

Also if I need to edit anything in this post, just let me know.