#fmd

[fatemoonsdoll]

When the mermaid cry, the tear will become the pearl

[karanliktangelenkiz]

Öylesine güzel bir gökyüzünün altında bu kadar kötü insan nasıl yaşayabiliyordu?

~ Beyaz Geceler, Fyodor Mihailoviç Dostoyevski

[anxiously-avoiding]

If I was faking I could make it stop. If I was faking I could make it stop. If I was faking I could make it stop. If I was faking I could make it stop. If I was faking I could make it stop. If I was faking I could make it stop. If I was faking I could make it stop. If I was faking I could make it stop. If I was faking I could make it stop. If I was faking I could make it stop. If I was faking I could make it stop. If I was faking I could make it stop. If I was faking I could make it stop.

[bunnymint98]

Fatemoons/Fatestars 1/6 Pinecone/Song Guo

Height without head: 23.3cm

Head circumference:17.5cm

Neck circumference :5cm

Shoulder width:4.5cm

Chest circumference: 9.9cm

Waist circumference:9.3cm

Hip circumference:15.2cm

Thigh circumference:9.4cm

Calf circumference:6.3cm

Leg length:14.5cm

Foot length:3.5cm

Foot width: 2cm

[head-post]

Slovakia declares state of emergency amid foot-and-mouth disease outbreak

The Slovak government imposed a nationwide state of emergency following confirmation of a fourth foot-and-mouth disease (FMD) case at a livestock farm in Lúč na Ostrove, Euractiv reported.

The measure, effective from 1 p.m. on Tuesday, grants authorities enhanced powers to contain the highly contagious animal disease. The state of emergency enables rapid deployment of veterinary teams and streamlined procurement of vaccines.

Crisis team headed by Interior Minister Matúš Šutaj Eštok convened on Tuesday evening.

Prime Minister Robert Fico warned of potentially “astronomical” damages to Slovakia’s agricultural sector, with meat and milk shortages likely to be the main challenge.

This is a deadly serious matter.

A fourth case of FMD was confirmed by Agriculture Minister Richard Takáč, prompting the authorities to take drastic action.

Read more HERE

[longhaulerbear]

The study demonstrates that both long COVID and ME/CFS patients exhibit similarly impaired endothelial function, indicating potential vascular involvement in the pathogenesis of these post-viral illnesses. The significant reduction in flow-mediated dilation values suggests an increased cardiovascular risk in these populations, warranting careful monitoring and the development of targeted interventions to improve endothelial function and mitigate long-term health implications.

[fatemoonsdoll]

what are you thinking now

[omxseo]

Types Of Carotid Artery Diseases • Carotid artery stenosis • Aneurysm • Carotid artery dissection • Carotid body tumor • Fibromuscular dysplasia (FMD) • Innominate artery disease • Recurrent blockages" . Dr. Harshvardhan Oak www.punevascularcentre.com

[keepdiettips]

Discover the benefits and science behind the fasting mimicking diet. Learn how this innovative approach can promote weight loss, improve health.

[myriadghost26]

" Why can't it be in this lifetime? "

The question I have in my head, should we have met much earlier in life and fell in love, would things be different?

I hate that I have to let you go, i hate that you can't choose me, i don't want you to be just a part of my memories. I don't want you to forget about me. I'm selfish went comes to you, i don't want my place in your heart be taken by anyone else. I wanna feel everything with you.

I have so much more to say, many word left unsaid, many thoughts spiraling in my head. But still can't answer "why can't it be in this lifetime"

[firstmedicaldiagnosticspvtltd]

Psoriasis – an inflammatory skin disease

Scientific / August 27, 2022

Psoriasis a serious global health problem, with at least 100 million individuals affected worldwide (according to the WHO Global Report on Psoriasis (1)). The incidence varies between 0.09% and 11.43%, depending on geography and ethnicity.

In Europe, Nordic populations are more affected than Mediterranean, and a higher prevalence is observed in Caucasians than in Asians and African Americans1. Since the famous Greek doctor Hippocrates described the disease for the first time around 460 BC, doctors have been trying to unravel the mystery of its origins. Today, they still don’t know everything about the causes of psoriasis. The tendency to become ill lies in a genetic redisposition, but external/internal triggers or risk factors cause an outbreak. Only when they come into play, the skin cells are affected by inflammatory processes and begin to multiply uncontrollably. The dermatologic manifestations of psoriasis are varied and psoriasis vulgaris (also called plaque-type psoriasis) is the most prevalent type. Usually, the affected skin areas are outside of the elbows, knees or scalp, but can also appear on other locations – such as the eyelids, ears, mouth and lips, hands, feet and nails. Clinical features, especially size and distribution of the psoriatic lesions, allow classification of psoriasis into plaque, guttate, pustular, and erythrodermic types (2–5). The quality of life due to psoriasis can be very much decreased, causing reduced work productivity, physical disability, depression and impaired social relations (6,7).

Environmental factors can negatively influence the onset of symptoms and the severity of the disease. Usually, several risk factors trigger the onset of psoriasis, such as psychological stress, skin injuries, infections (e.g. Staphylococcus aureus, Helicobacter pylori, Candida sp. Streptococcus sp. or HIV), hormone fluctuations, medication (e.g. lithium, TNF inhibitors), smoking or alcohol consumption. Overweight – especially excessive abdominal fat that promotes inflammatory processes, is another important risk factor for psoriasis (8). Obesity promotes a low-grade inflammatory condition, whereby the adipose

tissue is an active endocrine organ that has a key role in inflammation, glucose and lipid metabolism or insulin-mediated processes. The relationship between the two conditions seems to be bidirectional, with obesity predisposing to psoriasis and psoriasis favouring obesity (9).

By adopting an appropriate anti-inflammatory lifestyle, psoriasis patients can themselves contribute to less frequent and less severe relapses. These include an appropriate diet, overweight reduction, avoidance of alcohol and cigarettes and the ability to cope with stress.

What happens in psoriatic skin lesions?

The hallmark of psoriasis is sustained inflammation that leads to uncontrolled keratinocyte proliferation, dysfunctional cell differentiation and an accelerated processes of skin renewal. In psoriasis, the immune system mistakenly targets the body’s own cells, which causes an immunological overreaction, as it occurs in many other autoimmune diseases. An excessive number of new skin cells are constantly formed. Normally, the epidermis renews itself within four weeks, but in psoriatic patients this occurs in only three to four days.

What happens in the affected skin, however, can be observed thanks to modern scientific methods. Psoriasis is considered as a T-cell-mediated inflammatory skin disease. The T cells of the immune system (specialized white blood cells) and the so-called Langerhans cells (immune cells of the skin that are located in the lowest layer of the epidermis) play a key role. Langerhans cells sense any kind of “danger” and constantly monitor the environment of the skin for “unsafe”

situations. Immune cells are then sent out to collect information about any “trespasser” and the body can decide to produce inflammatory signals to fight off the “attack” by creating an allergic reaction or forming scar tissue.

In a psoriatic patient, Langerhans cells take up the body’s own cells, which are erroneously classified as dangerous (autoantigens). Then they migrate from the epidermis via the lymph stream to the lymph nodes and present the autoantigen to the T-cells. As soon as the T-cells have recognised the autoantigens via special receptors, they become active and release a whole series of cytokines as messenger substances.

The result is an inflammation of the skin, with the typical symptoms of skin redness, swelling and itching, which is kept going by the constant activation of immune cells and messenger substances (Interleukins such as IL1β, IL17, IL22 IL23, and TNF-α). When the body attempts to heal the inflamed area, the cells of the skin (keratinocytes) multiply excessively. They migrate too fast from the lowest to the uppermost skin layer. This excessively rapid cell renewal leads to an accumulation of immature cells on the skin surface and the formation of a large number of scales that appear as patches or plaques (2,10,13,15).

In this reasoning, treatment of psoriasis must consider the underlying causes and eliminate or alleviate the body´s systemic inflammatory load. This can be achieved by nutritional adjustments, for example according to the results of the ImuPro test.

Nutrition plays a crucial role in psoriasis

Nutritional and lifestyle counselling must play a central role in an integrated therapeutic approach for psoriatic patients. They should actively participate to prevent or reduce overweight, diabetes, cardiovascular and metabolic diseases or other conditions related with chronic inflammations. Hypocaloric diets were shown to be helpful to patients with psoriasis who are overweight or obese, leading to significant improvement in psoriasis severity (16–24). However, the consensus regarding the nutritional strategies to be adopted still lacks in clinical settings.

A gluten-free diet can improve psoriatic symptoms.

A number of studies have examined the effect of a gluten-free diet (GFD) on psoriasis severity. The impact of a 3 month gluten free diet was evaluated in 33 psoriasis patients with elevated antigliadin antibodies (AGA), compared to 6 psoriasis patients without elevated AGA. Seventy-three

percent of the AGA-positive psoriasis patients showed an improvement in their psoriasis area and severity index (PASI), compared to none of AGA-negative psoriasis patients. After the GFD, AGA values were lower in 82% of the psoriasis patients who improved (25).

In another clinical trial with 28 patients, a gluten-free diet was shown to decrease the expression of tissue transglutaminase in psoriasis patients with AGA positivity (26). Numerous other reports document the rapid resolution of skin lesions and clearance of the skin in psoriatic patients following a gluten-free diet (27–32).

In addition, many health care providers agree that a diet based on a test for delayed food hypersensitivities – such as ImuPro – is helpful for the treatment of patients suffering from psoriasis.

A few years ago, ImuPro undertook a clinical observation study, to collect evidence on the efficacy of ImuPro300 in patients with very different conditions that may indicate food intolerance, including psoriasis, neurodermatitis, headaches/ migraines, overweight/obesity, fatigue, rheumatic diseases

or gastroenterological complaints. A total of 938 patients participated in this trial and eliminated IgG positive foods for a period of 8 weeks. Initially, 201 patients indicated that they suffered from psoriasis. In the control documentation, which took place after approximately 8 weeks, the severity of psoriatic symptoms was significantly lower in 118 of the 201 patients (59.2%). Comparable improvements were also found for other inflammatory skin diseases such as

acne, neurodermatitis or itchiness (60.8%, 66.9% and 72.5%, respectively) (33).

The results of the ImuPro observational study show that an individualized anti-inflammatory nutrition should be a considered as first line intervention, affecting disease severity and management of patients with psoriasis.

[cathygeha]

REVIEW

My Genes Don’t Fit by Amy Jarecki

Informative, compassionate, realistic look at a genetic disease that impacts a mother and daughter as they face big changes in their lives. This book sees both women dealing with health issues while also both finding deep abiding, loving, and accepting partners.  Well written and thoroughly enjoyable ~ I have loved every book I have read by this author!

What I liked: * The medical information and the impact it can have – as an RN – fascinating

* The relationship between Jane and her daughter Meg and how it grew and developed through the story

* The “awakening” Jane had regarding what was really important in life

* Meg’s relationship with Mike and how romantic, supportive, and caring it was

* Jane and Bob together seemed a great fit and perfect for one another

* Finding out who contaminated a product in the business that Jane was in charge of at the beginning of the book

* That when Meg and Jane found specialists to tend their medical needs, it made all the difference. It once again affirms to me that a second opinion is not a bad idea.

* The plot, pacing, setting, and writing

What I didn’t like:

* Who and what I was meant not to like – there were a few

* Thinking about how difficult it might be to live with FMD and/or vEDS

* Not knowing how Jane, Meg, and Zachary will do in the future

Did I enjoy this book? Yes

Would I read more by this author? Yes

Thank you to Booksprout and the author for the ARC – this is my honest review.

5 Stars

BLURB

A deeply poignant novel about the resilience of the human spirit when two women face unforeseen catastrophes. Jane is at the height of her career, confident, fearless, and commanding. Her daughter Meg is loyal, hardworking, and a tad eccentric. Both women consider their lives to be perfectly on-target. Jane will become her company’s CEO. Meg will marry and own a quaint house in a picturesque Midwest town. Perhaps Mr. Right will be the doctor Meg meets on her birthday cruise? Yes. Everything is falling into place exactly as it should be.

[fatemoonsdoll]

Reading before go to bed

[bibliomancienne]

Enquête Réconciliation-Équité-Diversité-Inclusion sur les métiers et professions documentaires au Québec : vers un portrait de la réalité québécoise au temps de la superdiversité 

Agora de la nouvelle bibliothèque Maisonneuve (Montréal, Québec) La société se caractérise désormais par une superdiversité (Vertovec 2007) et, de fait, les publics des milieux documentaires aussi. Les métiers et professions documentaires sont préoccupés par la question de la représentation des diverses communautés et celle de leurs membres dans leur rang. On s’interroge dès lors sur le profil en…