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Vaccination Clinic In Singapore | AcuMed Holdings
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AcuMed Holdings Pte Ltd proudly presents its state-of-the-art vaccination clinic in Singapore, dedicated to providing high-quality and accessible healthcare solutions. Our clinic is committed to safeguarding the health and well-being of the Singaporean community through comprehensive vaccination services. 
At AcuMed Holdings Pte Ltd, your health is our priority. Our clinic is staffed by a team of experienced and compassionate medical professionals, including doctors and nurses, who are dedicated to administering vaccines and offering expert guidance.
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xtruss · 1 month
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We're Having A COVID Summer Surge. Should You Get The Updated Vaccines Now?
The FDA Just Approved an Updated Vaccines, and Officials Say Paxlovid is Still Effective in Preventing Severe Cases.
— By Sanjay Mishra | August 22, 2024
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A Colorized Ccanning Electron Micrograph of a Cell (Blue) Infected with the Omicron Strain of the SARS-CoV-2 virus (Yellow). Micrograph By National Institute of Allergy and Infectious Diseases (NIAID)/National Institutes Of Health/Science Photo Library
The summer of 2024—the fifth since the COVID-19 pandemic began—is projected to be the biggest summer wave of COVID infections to date.
Since early May, COVID infections have steadily increased in the United States, Europe, Singapore, New Zealand, and Australia. The U.S. Centers for Disease Control and Prevention estimates that COVID-19 infections are currently increasing in 25 states based on data from emergency department visits. However, hospitalizations and deaths from COVID remain at their lowest levels.
Now, the U.S. Food and Drug Administration has approved updated vaccines to protect against current variants of the virus.
This recent surge has been driven mainly by a new group of closely related Covid subvariants, known collectively as "FLiRT."
As the summer winds down, students across the U.S. will return to school. Traditionally, this also coincides with the season of respiratory viruses, such as flu, RSV, and increasingly COVID.
"Not sure what will happen this fall and winter," says Kei Sato, a virologist at the University of Tokyo. While the FLiRT variants are likely to keep evolving after summer, entirely new subvariants cannot be ruled out. "An Omicron-like event” seems to have occurred every year in the fall since 2021, says Sato.
Here's what you need to know about the new variants and the new vaccines.
What Are FLiRT Variants?
The "FLiRT" variant family includes the majority of currently circulating variants, identified with the letters KP, JN, and the variant LB.1.
The unofficial name "FLiRT" is an acronym for a set of mutations on the spike protein of SARS-CoV-2, the virus that causes COVID-19. The virus uses spike protein to bind with ACE2 receptors in our nose and lung cells to cause infection.
All proteins are made up of amino acids that string together like beads. Mutations can change one amino acid to another, thereby altering the behavior of the protein and making the virus more or less infectious, or able to dodge immunity.
The FLiRT subvariant family members are descended from the JN.1 variant that was dominant in the U.S. in early 2024. JN.1 itself was highly unusual because it acquired 41 mutations that differentiated it from Omicron XBB.1.5, which is the variant upon which the current bivalent COVID booster is based.
Should You Get The New Vaccines?
The two updated mRNA vaccines, manufactured by Pfizer-BioNTech and Moderna, target a FLiRT variant called KP.2. Anyone over the age of 12 can get the new shots, as long as they haven't received a booster in the last two months.
“Vaccination continues to be the cornerstone of COVID-19 prevention,” Peter Marks, director of the FDA’s Center for Biologics Evaluation and Research said in a statement.
Another vaccine targeting the variant JN.1 and manufactured by Novovax is also under review and could be approved soon.
Previous research also showed that older vaccines based on XBB.1.5, an earlier subvariant of Omicron, were still effective in preventing severe COVID-19. While this vaccine produces antibodies that still target the FLiRT variants, the efficiency is notably reduced. A recent infection from the JN.1 variant also seems to provide strong protection against all the FLiRT variants.
That said, the CDC recommends that everyone six months and older get a COVID vaccine. Those at high risk for serious COVID-19 should get vaccinated with the most recent versions available.
How Alarming Are FLiRT Variants?
Coronaviruses, such as SARS-CoV-2, frequently mutate to avoid recognition by antibodies. The two FLiRT mutations remove the sites on the virus where antibodies bind the SARS-CoV-2 virus.
Additional mutations on the FLiRT variants can either help the virus bind more efficiently to ACE2 receptors making it more infectious, help it evade previous immunity, or both, says Adrian Esterman, an epidemiologist at the University of South Australia, Allied Health & Human Performance in Adelaide, Australia
Early studies show that all existing FLiRT subvariants are very good at dodging previous immunity acquired through multiple COVID vaccinations—including the most recent COVID bivalent booster—or a breakthrough infection from a previous strain of Omicron.
But the good news is that by escaping the antibodies, the FLiRT variants have also seem to lost some ability to infect their target because the virus needed the original antibody-binding sites to bind the ACE2 receptor and enter cells.
"These variants are not yet particularly concerning, even with the new mutations that affect certain aspects of the virus's biology," says Shan-Lu Liu, a virologist at the Ohio State University.
It is common for viruses to acquire mutations that help them dodge immunity, which can affect their ability to infect cells, says Liu. "The viruses can quickly evolve new mutations to restore their infectivity."
But in the meantime, Sato thinks that waning immunity from previous vaccinations and infections, coupled with the FLiRT variant's ability to dodge remaining immunity, are probably the main reason for the recent surge in infections.
Liu also agrees that the currently rising numbers of COVID infections are mostly due to low booster uptake and increased summer travel.
Are COVID Medicines Still Effective?
Emergency department visits, hospitalizations, and deaths have all spiked during this summer but are still much lower compared to earlier waves of the pandemic.
There is no indication that these new FLiRT variants are more dangerous than other Omicron strains.
A study shows that Paxlovid is still effective against FLiRT variants. Other antiviral drugs such as molnupiravir and remdesivir are also expected to work since their mechanism of action is not affected by mutations in the spike protein.
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mazelikedays · 2 years
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2022 Year Ender
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Currently Listening to: Yoasobi - Gunjou Location: Dubai, United Arab Emirates Mood: Kinda chill If you see the picture, then you’ll see me at the bottom left. Finally, a Weiss Schwarz BCS Top 8 spot! On a side note, apparently my livejournal account is still alive, and I discovered my year end posts from 2006 are still alive. So I have been doing year end posts for the past 16 years. Kinda scare to read the earlier ones, since they’re likely cringey stuff. Anyhow, let’s do the 2022 edition of my year ender report! 
1. Last year, I was talking about COVID. Funny enough, I ended January 2022 with contracting the COVID virus. It just felt like a flu honestly, and I was working from home 2 days after. Thankfully though by the time of writing it was more or less dying down (except in China I think) and most countries have opened up.  Hopefully it finally becomes endemic this 2023, but then again most countries don’t care anymore as long as you are vaccinated.
2. A year came by, and I’m still here in Dubai. It’s not bad honestly, a few things happened here and there (like work from home due to my COVID stint, then having an issue with a crappy client who left months later), but overall it’s chill. I’m also getting an increase on January, which is some nice news. However, I still feel I can go elsewhere. I tried going back to Singapore, but unfortunately the job prospects there wasn’t that good. I actually got frustrated when I wasn’t able to get a job there around March/April. But then, something came up and now I’m gunning to go to either Canada or Australia, whichever invites me first. I have submitted my requirements for Canada and I’m still waiting for my final assessment for Australia, so let’s see. These things take time, but hopefully before July there would be some significant news. I’ll also try to apply to increase my chances.
3. Travel wise, I was finally able to go out of the country again as COVID restrictions got relaxed. I started the year with going to Bahrain, though unfortunately after the trip I got COVID. And then in May I was finally able to go back to the Philippines after 2 years, catching up with a lot of my friends. I was even able to go to places like Mindoro and Boracay. It was a fun and busy month for sure! Funny enough, I went to the Philippines again last October to play for WS BCS, and finally went to Singapore again this December. 
4. TCG wise, speaking of Singapore, I finally got a Top 8 placement this year! I won in the WS BCS Singapore Regional. I won using my Tokyo Revengers Dual Lane Pah-Chin deck! Finally, after playing for 8 years, I finally got a top spot! Unfortunately, I didn’t go past that as my deck decided to not cooperate, hehe! I also played in Manila last October but unfortunately lost to the guys who went Top 1 and Top 8 as well. For next year, I’m hoping to go higher and also to participate in the WS BSF in Manila so I can finally play an official team tournament major!
5. In terms of my weight, I got off to a good start. I was able to go as low as 79kg, the lowest I had since probably after childhood. Stress and non-activity though kinda made me gain weight, and going to Singapore pretty much made me fat. Now I’m at 85kg, so I finally bought weights and a stepper so that I can burn calories even if my place is small. As for cooking, I haven’t cooked new stuff lately, mostly repeat dishes. I also got lazy posting food pics and I had to cram a lot in a post recently. Hopefully the goodies I got from SG will motivate me to cook new dishes! 
6. Anime, Manga and Pop Culture stuff.
I think for anime and manga, this was the reverse of last year. I watched more anime and read way less manga. I think the reason for this is that a lot of the manga I have been reading have ended this year.  As for sumo, I’m still pretty much into it, and it was fun to see new winners. I felt the sumo season ended pretty weird though, with only Takakeisho left as Ozeki, and Abi winning out of nowhere, albeit in a kinda off manner. There’s a lot of up and coming new talent though, and I’m excited to see them rise!
Currently Watching:
Gundam: The Witch From Mercury S1 Planning to Watch: Engage Kiss, Jojo: Stone Ocean, Tokyo Revengers S2, Tomo-Chan is a Girl, Danmachi S4 Part 2, Bofuri S2, maybe Ayakashi Triangle? 
Finished This Year:
Hataraku Maou Sama S2, Rising of the Shield Hero S2, Princess Connect Re:Dive S2, Kaguya-Sama: Love is War S2 and S3, Danmachi S3 and S4 Part 1, Made in Abyss S2, My Sempai is Annoying, Mushoku Tensei S2, Komi-San, Mieruko-Chan, Kimetsu no Yaiba S2, Isekai Shokudou S2, My Dress Up Darling, Tokyo Revengers S1, Love After World Domination, Lycoris Recoil, Overlord S4, My Stepmother’s Daughter is my Ex, Tensei Shitara ken Deshita, Bocchi the Rock
Unfinished Anime: 86, Ranking of Kings
Finished OVA/Movies:
Yuru Camp Movie, Josee, the Tiger and the Fish, Metropolis, Her Blue Sky, FGO Camelot 2, FGO: Solomon, Quintessential Quintuplets Movie, Macross Delta Zettai Live, Fate Kaleid Liner Movies 1-2, 
New Manga Read:
Spy X Family, Ayakashi Triangle
Finished Manga: Tokyo Revengers, Dr. Stone Other Stuff Watched:
Movies: Eternals, Dune, How to Train Your Dragon 3, Rurouni Kenshin the Final, The Batman, Dr. Strange in the Multiverse of Madness, Thor: Love and Thunder, The Green Mile, 
Series: Trese, The Mandalorian, The Book of Boba Fett
New Games Played: Mainly just playing Mahjong Soul and Pokemon TCG. I actually tried Tekken 7 and FF14 but didn’t feel going all out. Also played Wordle until like a few months ago.
8. Fulfilled (or not) Wishes a. Hoping to go back to SG again. - I did, but only as a tourist. I’m aiming for somewhere like Canada or Australia now. My friend will go to the UK soon so I’ll check that out as well. b. A Significant Other - I tried last Valentines Day. Miserably failed. Will put this on hold until I can go emigrate elsewhere c. Get Healthier – It was going pretty well the earlier months, but certain events made me gain a good amount of weight as well.  d. Travel more - I was able to travel to Bahrain, then went back to PH and SG. I would like to travel to either somewhere new, or in Japan again as well. e. For this COVID-19 nightmare to finally end. - It’s pretty much normal already at this point, just waiting for COVID to get endemic status.
New Wishes:
a. Get Healthier - Need to get my weight loss back on track. Hopefully new equipment will work out in my favor b. Get to emigrate elsewhere - Canada seems to be the most likely now, I sure hope there’s some news soon before July. Will check out elsewhere too that is nice and has a WS TCG community. c. Travel to new places - It’s kinda unlikely unless it’s already like Canada or Australia, but I would like to go to somewhere new. Let’s see. I’m also gonna camp to Hatta for the new year. Before I leave Dubai, I sure would like to go to Jebel Jais and do the skydive as well
d. TCG wise - Hoping to finally play in a teams tournament, and get more Top 8 or higher placements. If I can get an invite to worlds and if it’s gonna be in Japan, the better!
Oddly enough, I don’t have much else to wish for, maybe just for good health for me, my family and my friends. Typing this now because I’ll be camping tomorrow in Hatta! Anyhow, till next year!
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pilcare-nce · 12 days
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Influvac Tetra 2023/2024 Vaccine - Inactivated influenza vaccine - Abbott - Pilcare - Exporter from India to Singapore
Influvac Tetra 2023/2024 Vaccine helps protect you from influenza (flu). It works by exposing you to a small dose of the flu virus which helps your body to develop immunity against the disease. Vaccination will not treat an existing flu virus infection.
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whattheabcxyz · 4 months
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2024-06-13
Singapore
594 people have lost $1.3m in online marketplace scams since April
Youth with less time and money find other ways of giving back
Geylang sees 1st million-dollar 4-room HDB flat sold
At least $16.3m lost since January to scammers impersonating ICA & Chinese government officials
Government SMSes will show "gov.sg" as sender ID from July
Transport
Singapore: Dozens of roads & lanes closed to vehicles on 15 & 22 June for NDP rehearsals
Health
We are even breathing in microplastics now - no thanks to all those polyester fabrics! 😡
Is COVID-19 to blame for the sudden rise in "unusual" cancers after the pandemic?
More about Moderna’s new 2-in-1 COVID-19 & flu vaccine - I won't be taking it, kthx
Food
FDA issues warning about paralytic shellfish poisoning - paralytic shellfish toxin is a naturally occurring biotoxin produced in some species of microscopic algae which can accumulate in shellfish when they feed on it
Science
James Webb space telescope detects earliest, most distant galaxy in known universe
Literature
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^ Harvard removes human skin binding of book in their collection - the skin supposedly came from a dead patient at a hospital where the book's 1st owner worked
Education
Penang schools wrestle with Malaysian government over science & maths classes in English
Gossip
Singapore: Veteran Channel 8 actors Zheng Wanling, Cai Pingkai & Yun Changcou make appearance in ads
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spoilertv · 1 year
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1kook · 4 years
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youtube & use lube
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part 7 of my netflix and chill collection!
summary: You can’t believe this is Jungkook’s preferred sick day treatment; YouTube, cuddles, and an ugly amount of lube.  warnings: smut in the forms of nipple play, handjobs, spit kink, face riding, unprotected, flavored warming lube, riding, praise kink, soft femdom, missionary bc his eyes are pretty, tit sucking, more jk has an impreg kink, oh and this is all subby kook rating: mature (18+) miscellaneous: domesticity baby!! fluff, soft scenes /.\, jk is sick:((, doyeon is A Doctor, yn sees an opportunity and she grabs it, surprise ending <3  word count: 8.7k  
notes: finally…. 7 parts later and we get ~✨💓sub kook💓✨~ this was honestly my fave to write I think because I was obSESSEDDD with his softness and yn leading hehe /.\ also yeah we time jumped 6 months bc uhmmm 😎 story progression also here’s [ THE KOOK U SHOULD IMAGINE FOR THIS 😡 ] also if see a typo ummm no u didn't .
let me know what u think! a simple ask goes a long way <3
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Despite what past experiences may dictate, Jungkook’s body is actually quite resilient. It’s due in part to his obnoxiously healthy lifestyle; avocado breakfasts, gym rat tendencies, and a normal person’s circadian rhythm (you could never relate). He lives the life health professionals can only dream of writing down in their notes, so careful of his well-being that it’s almost annoying. Of all the habits you help him break, the rituals he sometimes forgets, his health is never one and it’s actually one he ropes you into quite often. The ladder accident last summer had truly been an odd occurrence, and for a while after, you doubt anything else will ever happen to him. 
And then winter comes. 
Now, Jungkook, with all his superior bodily systems and strict lifestyle, is still not immune to the common cold. So when he comes down with a stuffy nose, a saggy frame, you’re not too surprised. It’s right after New Year’s, which you had spent it at one of Taehyung’s classic overcrowded parties this year, shivering on a rooftop as he kissed you silly under the fireworks, so one of you was bound to get sick. And you were sick for Halloween, so it’s only the universe’s way of leveling the playing field when he gets sick after New Years. 
What does surprise you is when he doesn’t bounce back right away. Usually, Jungkook’s high caliber immune system has him in tip top shape about two days later. But this time around, it takes a while. In fact, it takes longer than usual, and you don’t realize until you’re coming over on a Friday night, met with an unusual silence at the Jeon household. 
As you slowly grew accustomed to your life out of school, you and Jungkook accepted that you didn’t really have time to be glued to each other’s hips at all hours of the day. It was only natural that sometimes you had too much work, were too tired, or were just not in the mood to visit each other. That was fine, and you’ve come to quite appreciate this new routine, because it only made your heart flutter faster than before when you did see him next. You don’t have to see each other everyday, and that was fine; it was part of growing up together (and growing old together, your sappy heart says).
But today, this separation ends up being your downfall. Jungkook first showed signs of a cold on Monday, and now it was Friday and you hadn’t heard from him in two days. You’re beginning to suspect he’s come down with something severe— maybe that strain of the flu that he forgot to get vaccinated for this year —or even worse, dead.
Luckily, Jungkook isn’t dead, just sadly slumped across the end of his bed, nose a bright red and hair a tangled mess. “Oh no,” you frown, but there’s not an ounce of distress in your voice, because boy, was he cute. 
He groans at the sight of you. “Don’t look at me,” he whimpers, hands fisting the sheets. “I’m ugly.”
You bite down on a smile, hang your bag on the hook behind his bedroom door. He’s barely making an effort to stay on the bed, clinging to the side with such powerless hands. “Absolutely hideous,” you play along, arms wrapping around his middle. Registering your touch, your support, he immediately releases what little grip he had and almost sends the two of you tumbling to the ground. “My poor baby,” you croon, manhandling him back into the comfort of his sheets. 
Perhaps the reason you believed Jungkook was so immune was because, well, he never let you see him sick. 
He was picky about his presentation to the world, always wanting to show his best side. And well, you were in that world. Hell, you were probably the main person he wanted to show off for (not to toot your own horn), so he avidly avoided showing you his unpleasant sides. Even in college, when you had been practically stuck to his side, he had always made a big deal of pushing you away when he was sick, calling off dates and hiding away at his house. 
You sort of knew why. Namjoon had told you once that Jungkook when drunk was the equivalent of a needy, whiny baby. You could attest to that because wine drunk Jungkook and vodka drunk Jungkook were quite the experiences to haul home. And apparently Jungkook when sick was more or less the same. He was all doe eyes and pouty lips, magnified by his weakened appearance. He was adorable. 
He’s wearing a lot of layers, but it’s still winter so you don’t think too much of it. Dark long sleeve sweatshirt, the front tucked into some cute brown and black checkered pants. You see it as just some casual at home attire until you reach for his covers, hand brushing his hair from his face, only to find it ice cold. 
“Oh, you’re freezing, honey,” you frown, for real this time. Jungkook whimpers, snuggles into the sheets you pull up to his chin. He dozes off soon after, pouty lips chapped to hell and back. You reach for your chapstick, deciding to get one good use of it on your own lips before contaminating it with Jungkook’s sick germs. Even in his sleep he’s a good boy, rolling his lips together after you’ve applied it on him. 
With Jungkook knocked out, you pad back downstairs and into his kitchen. You can more or less infer that he’s come down with something a little more intense than a cold. His skin was cold, and his nose was runny, but, oddly enough, he wasn’t sweating. You decide to consult a professional. 
“The little gremlin is sick?” Doyeon repeats, a comforting buzz in your ear as you get to work making Jungkook your famous Get Better Soon Soup, idly waiting for the water to boil over. You confirm. Doyeon, legend that she was, accidentally sat an entire physiology class one semester (and passed), so this is the closest you’ll get to a doctor friend. “Hm,” she says, “what’re his symptoms?”
You press your phone between your ear and shoulder, clattering around Jungkook’s kitchen for ingredients. “Runny nose and colder than your ass that one time you passed out in the snow,” you supply. “Oh, but not sweating.”
Doyeon hums over the line, tells you to give her a second, and disappears. “WebMD is saying fever, but you said he’s not sweating?” You confirm again. “Throw him in front of the heater and make him sweat then. He has to burn it out somehow.”
“I can’t do that,” you sigh, pausing when you hear some vague sound from around the house. It’s not Jungkook, so you return to your call. Anyway, Jungkook’s house is, like, perfect. Always warm when need be and always cold as well. You don’t even think he knows what a space heater is. “He’s sick sick. Like, can barely hold himself up sick.” 
She scoffs. “And I care why?” You huff, go to scold her for their weird rivalry, but then she’s moving on. “Babe, just give him some pain relief and call it a day.”
“Fine,” you mumble. “Wait, can you look something else up for me?”
Anyway, Jungkook probably has a fever, except it’s weird because he’s not sweating it out. He wakes up about an hour later, but this time he’s more self aware. He eats his soup and takes the medicine you offer him. Afterwards, he can’t go back to sleep so he huffily asks for his iPad and begins watching some weirdly specific YouTube videos you don’t think you’ve ever seen him watch before. 
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You have absolutely no idea what he’s watching, some niche videos of guys in Singapore turning random forest areas into underwater pools? You don’t know. Jungkook seems interested, though, for all of ten minutes until he falls asleep again. 
He’s still cold, poor baby, nose like an ice cube that just won’t melt. You find a heating pad you left over in his closet and place it on his chest. Your thought process is that if his heart, the source of all energy, was warm, then certainly the rest of him will warm up soon enough. Yeah, you missed the last three seasons of Grey’s Anatomy; you were a little rusty. 
So with Jungkook fast asleep and nothing else to do, you assume the age-old, patriarchal task of cleaning around the house. 
His house was usually neat and tidy, mostly as a result of Jungkook’s virgo manifestations, but even those varied. His living room tended to be spotless, but his personal office was a different story. But with him having been out of it this past week, the entire house is littered in tiny garbage that would make Normal Jungkook burst a blood vessel.
There’s a pile of Reese’s wrappers in the downstairs bathroom, on the sink next to his toothbrush. The sight makes you sad, because your poor boy must have been struggling if he was eating candy in the bathroom, where he… uses the bathroom. And then that thought makes you even sadder, thinking back to all the times he was sick and alone, fending for himself out of his weird embarrassment of showing normal body functions. 
You had thought he was cute when you first arrived— he still was —but he was also so weak and frail, bulky muscles rendered useless by whatever bacteria was attacking his body, making him sleepy and in pain for god knows how long. With a resolute nod, you sweep all the wrappers into the trash and decide to do your very best at helping Jungkook get through this sickness and bounce back better than ever. 
Before leaving his bathroom, you ransack his cabinets, deciding he probably keeps most of his antibiotics here. It’s a spot you never really snoop around, because Jungkook always keeps a fully stocked basket in his closet filled with your typical necessities— from conditioner to pads to nail polish remover, he kept it all. And furthermore, you always tended to use his upstairs bathroom anyway, so that’s where your toothbrush and the like were kept. There was really no need for you to ever look through the downstairs bathroom’s cabinet. So the downstairs bathroom cabinet is practically the other side of the world to you, a culture shock so strong it has you plopping down in front of it to thoroughly sift through. 
He’s got a disgusting amount of hair products, none of which you actually think you’ve ever seen him use, and a maniacal amount of tooth stuff. Now, you were quite possibly the biggest proponent for dental care, but this was ridiculous. Four packs of floss on reserve, and about three cases of those dental picks. A whole family pack of toothbrushes and one of those cute little cases for his retainer you’ve seen a few times. 
So overwhelmed with his ungodly stash of dental hygiene utilities, you almost miss the pretty pink tube hidden in the very back corner. 
You’re thinking it’s some makeup primer you left before that he mistook for moisturizer, probably dumped it with all his other things, only to find out you are very, very wrong. 
Sensation Warming Lubricant: NOW! in strawberry flavor 
You blink. 
Lubricant? Jungkook was using lubricant? Strawberry, sensation warming lubricant?!
Somewhere in your mind you had convinced yourself that Jungkook was a simple man, a lotion at his bedside drawer type of man. He had you for the last one and half year, and you two fucked like rabbits, so you hardly doubt he was jacking it alone these days. And even if he was, why on earth was he so specific about the type of lube he uses?
You turn the bottle around, eyes scanning for an expiration date or something of the like, only to find that the copyright symbol was under this current year. The year that had just started, like, two weeks ago. 
Oh, so this was new. 
You turn it over, eyes scanning over the warnings like it’ll tell you something about your boyfriend you don’t know yet, some other hidden secret that he’s maybe held from you. Granted, owning lube isn’t really a big deal, but the fact he’s got it so hidden away (not really, it was casually sitting beside his sunscreen) was definitely something to zero in on. 
Strawberry flavored, you read again, warming, stimulating, edible? Forget his weirdly extensive floss collection, you had stumbled upon something amazing in here, the goddamn Hope Diamond among snooping girlfriend finds. You’ll confront him about this later, you decide, when he’s back to normal and not whiningly calling your name from upstairs. You pocket it for now, tucking it into your cardigan pockets for said later interrogation, and bound up the stairs to him again. 
He’s sitting up in bed like a very angry and confused toddler, brows furrowed sharply like he’s mad. Actually, he just can’t see, the light from the hallway blinding him, so you shut the door and flick on his bedside lamp for him instead. “Hi, honey,” you coo, sitting down on the edge beside him. He’s still waking up, leaning a little too heavily into your palm when you cup his face. “How’re you feeling?”
“Terrible,” he rasps out, but he’s definitely looking better than before. You don’t know if you imagine it, but there’s this slowly accumulating sweat that forms along the base of his neck. “Please don’t leave again,” he says softly, droopy eyes glassy. 
Something shoots straight to your heart— an arrow from Cupid himself! —that makes you stroke his cheek tenderly until his eyelids are fluttering shut again. “I won’t,” you promise, feeling around for his iPad. He doesn’t seem like he’ll fall back asleep, sitting up with more strength than he had that morning. 
You end up climbing behind him, let him be the little spoon you know he secretly craves to be, as he watches his weird YouTube videos again. His body is so warm against yours, but his skin is still so cold. If what Doyeon had said was true, it’s no wonder he’s kept the same sickness all week. The rhythmic sound of machetes hacking at the earth and water trickling through bamboo pipes grows on you, makes you fall into a sense of comfort behind him, arms tracing circles over his chest. 
It’s a mindless habit, one you actually do a lot. Most of the time, it’s when he’s at his desk and stressed out, your masseuse hands making an appearance to soothe the muscles in his neck and chest from being hunched over for so long. Even now, your fingers unconsciously press into the fabric over his pecks, tickle up his sternum until he’s melting against you. 
It takes one quiet whimper from him to let you know exactly how he’s feeling. “Everything alright?” you inquire, halting your movements over his chest. Jungkook nods shakily, head lolling forward. The nape of his neck calls to you, whispers for a kiss that you tenderly bestow upon it. It makes Jungkook jolt, another pretty sound leaving his lips at the press of your warm lips against his sensitive neck. 
“No more,” he mumbles, rolls his head around until it’s resting against your shoulder, giving you a clear view down his chest. You slide your hands back up from where they’d gone stiff just around his ribs, let them palm over his pecs. Jungkook’s hips buck, a minuscule movement you almost miss. 
His heart thunders like the inside of a horse race track beneath your palm, breath picking up just from the simple motion of your hands on his chest. It’s on the fourth circle around his pecs that you feel your pinky briefly catch on something. “Poor thing,” you sigh, running the pad of your pointer finger over the hardened nipple that peaks beneath his sweatshirt. “Is this what was bothering you?” 
A shaky exhale in response, hands tightly clutching at his iPad and beloved YouTube video genre. “N-No,” he denies, but you chance a peak at his face, where his lips are bitten a rosy pink color, its slightly muted sister rushing down his cheeks, over his neck. 
You press the lightest of kisses to the side of his neck, and he shivers. “Need me to take care of you?” you purr, trail your hands down his chest towards where the hem of his sweater sits. You run your finger over it twice, before moving to slip your hand beneath. Your fingers brush along his abs, contracted tightly at your touch, and slowly make their way back up his chest. 
Fingers find his pebbled nipples, a gasp escaping his lips. “Does this feel good?” you ask softly, pinching the swollen nubs between your fingers. Jungkook groans, body arching just the slightest as you rub his nipples, tug and twist them until he’s a whining mess. “Need you to tell me, honey,” you encourage, lips ghosting over his neck. 
The second kiss has him flinching as well, head rapidly turning the other way as you slowly kiss over his neck. “___, please,” he pants, knuckles pale on the sides of the iPad. You're afraid it’ll snap, if not from his grip then from the way he pushes at it, like he’s breaking a wooden board over his knee. It’s still on YouTube, playing another video from the same collection, volume competing with Jungkook’s tiny sounds. 
Pressing your lips to his neck, you kiss along it slowly, reveling in the lovely noises that Jungkook produces the more you rub his nipples, lower body squirming animatedly before you. Your kisses grow wet for a short period, suck purple blossoms across his skin until Jungkook is quivering like a leaf. “E-Enough,” he begs, voice a wobbly mess that is so light and airy. 
You grin, giving his rockhard nipples one last flick before sliding your hands down his chest, over his stomach to toy with the elastic of his pants. He inhales sharply, iPad nearly snapped in half mid video. Ready to play with him some more (and slightly afraid for the future of his tablet), you reach out a hand to move it away, set it off to the side. 
But Jungkook doesn’t release it. In fact, he clings to the damn piece of tech tighter than before. “Hmm?” you murmur, bottom lip brushing against his neck once more. “Not letting go, sweetheart?” 
He shakes his head, soft crown of curls bouncing from the movement. “Can’t, can’t,” he shivers. His knees shift back and forth, move between being casually spread and flush together. Like he’s hiding something, using the iPad and the videos on screen as cover. You tug at his wrist and Jungkook shakes his head again. 
You change tactics, hand sliding around his wrist instead. The other travels up, up, up, comes curling around the base of his neck. Jungkook whimpers, tilts his head back for you cutely at the first brush of your fingers against his Adam’s apple. “Thought you were my good boy?” you ask, eyes zeroed in on the tremble of his lower lip. 
Jungkook exhales shakily, a rather torn expression crossing his features. “I am,” he insists, fingers still tight “I am your good boy.”
You smile, stroking the front of his neck softly as you lean down to press a kiss against his cheek. “You are, aren’t you?” He whimpers. “Then let go, honey,” you murmur, hand on his wrist giving another experimental tug. Still, his grip remains solid. “Jungkook,” you snap, “let go.”
“Y-You’ll laugh,” he cries, yet his grip slowly weakens. It’s with a swift tug that the iPad tumbles to his side, presses against his hip, and shows you the raging hard-on that stirs beneath the front of his cotton pants. Pressed nearly beside your ear, Jungkook shivers. 
Ever so slowly, your hands return to their place around his waist. “Why would I laugh, sweetheart?” you mumble, marveling at the way his cock twitches and jumps beneath his pants before you can even touch it. His shirt is hiked up just above his abs, your hands tenderly stroking over the skin beneath his navel, but it’s got Jungkook writhing. “Hips up for me,” you instruct. 
He shakes even when he pushes himself up, knees wobbling as you slip your hands beneath his waistband and tug them down his thighs. Afterwards, his legs flop forward flatly, spread out with his beautiful swollen cock on display against his hip. 
You trap it at the base and Jungkook mewls, hands fisting the sheets now that his beloved iPad has been snatched away. It’s still playing his videos, interrupting his saccharine moans with corny ads every few minutes. A hand snaps up to join, opposite of yours, until your fingers are entwined around his dick. How romantic, you think, discreetly rolling your hips back against the mattress. “Gonna help me make you cum?” you ask instead, give him a light squeeze that makes him jolt. 
“Uh huh,” he responds, feathery. 
You reward him with a kiss to his cheek, reaching up to brush away the hair that’s begun sticking to his forehead. In the very back of your head you recognize this as being good for his fever, but the rest of you is more concerned with the pretty pout on his lips. “Hold tight for me,” you smile, releasing his cock to press your finger against the very tip of his cock where a pearly drop of precum has begun forming. “So pretty, Jungkookie,” you praise, teasing the length of your finger over the slit on his head. It has that juicy droplet coating your finger, gliding seamlessly over and over again. 
The simple touch makes him buck, has him blindly wrapping an arm around your bent knee that was pressed to his side this whole time. He squeezes around you rather weakly, the majority of his strength going to holding his cock tightly like you’d instructed. He’s such a good boy for you, trying his absolute best, even when you’re very obviously overwhelming him. 
You roll the flat side of your finger over him, his mushroom tip slowly growing more and more slick as he produces more precum. It’s shiny, fits perfectly between your clasped fingers when you squeeze around his head. Jungkook’s breath turns labored. 
He’s always so well kept down there, skin so smooth and free of hairs, and you know he does it because he wants to impress you. “So pretty, baby,” you hum, acknowledging his efforts. Your praise makes Jungkook moan, suddenly fucking up into his hand. It’s accidental, because he hisses at the drag of his dry palm around his relatively dry dick immediately. 
“Hurts, hurts,” he whimpers prettily, lower lip caught between his teeth. 
You frown, slide your wet fingers down the base of his cock until they’re wrapping around his and Jungkook’s little gasps even out. “I’m sorry, baby, you gotta be patie—“
Something presses against your hip, something distinctly hard that you had hastily picked up from his bathroom cabinet earlier, and a whole new door opens before your eyes. “Hold still for me,” you tell him quickly as you release your grip around his cock. Jungkook wails at the separation, but you’re more concerned with wrestling the tube out of your pocket with one hand. It’s heavy in your palm, turning over until that big fat label on front comes into view again. 
Jungkook explodes at the sight. “Wh— Where did you find that?” he stammers, cheeks ablaze. “I-I don’t know where that came fro—“
You ignore him, hold the bottle of lubricant over his stomach as you uncap it, a gooey pink substance spilling over into your hands the moment the lid pops off. Jungkook is still rambling away about the origins of the bottle, as if you care. You set the bottle on his tummy, the cold plastic makes him shiver. But you know what’s not cold? The warming lube in your hands that only takes three rubs of your palms to activate. 
You latch down like a crazed animal around his cock. With both your hands fighting to grip at his cock, you’re pressed closer against Jungkook, lips against the shell of his ear. 
The initial touch makes him sob, back arching and legs kicking at the sheets piled at the foot of the bed as your slick hands track the lube over his dick. “No!” he cries, hands wildly reaching out to grab whatever he can as you slowly get to work pulling him off. “I-I can’t, __, I can’t.”
“You can,” you coo, watching the translucent pink substance coat his cock, join his sticky precum. 
Maybe you get overexcited in your efforts, forget Jungkook is the way he is right now because he was still a little weak from his fever, but you go crazy on stroking his cock. One hand lingers around the base, squeezing and rolling over his balls, palm pressing against the hardened sac and squeezing there too. The other focuses at the tip, does most of the actual stroking over his cock. His head is leaking precum now, every stroke and squeeze making him shudder and push out another drop, until it’s mixing with the lube to form a sticky sweet substance that you wanna lick at so bad. 
So you do. 
You release one hand to curiously bring it up to your face, turning it over and around as you examine the stickiness on your fingers, the fat drop that unintentionally drips onto the front of Jungkook’s sweatshirt. He sobs at the sight of your lips around your fingers, squirms and bucks into the hand still on his cock until he’s embarrassingly coming. “I’m sorry,” he wails, hands fisting the sheets, fucking into your hand like a virgin. “I didn’t— I didn’t mean to.” 
You draw your hand away, watching in slow motion the cum that just spurted from his cock come dribbling down the slowly softening length now. “Oh, sweetheart,” you croon, hands on his tummy. The bottle of lube slips to the side, meets the still playing iPad at his hip. It’s sticky and gross to touch him like this, especially when you know Jungkook hates being unnecessarily dirty, but you can’t stop yourself from softly caressing him, soothe him after such a hard-hitting orgasm. 
Honestly you had thought he would hold up a little more, let you get in a few more strokes, but he must’ve been more sensitive than you thought. “I’m sorry,” he cries again, head lolling to the side to meet your gaze with watery eyes. 
You tilt his head to the side, angle him just right for you to bestow your first kiss of the night against his little pout. Jungkook hiccups, melts against you as you slowly guide him through the kiss. He’s sloppy and shy, moves nothing like your normal Jungkook, and that fact alone has you slipping your tongue past his lips. He doesn’t fight back, just lets you play with him and sighs all delicately against your mouth. 
There’s something about this, his soft and submissive attitude, that has you pulling away to look at him. Big brown eyes, glassed over with unshed tears, and plush lips that call your name. And yet. 
“Open,” you murmur, hypnotized by the way that tiny mouth moves. 
“Huh?” Jungkook flushes, but he’s so good, he’s your good boy, and does so anyway. Lower lip quivers as he parts his lips, stuttering exhales creeping through as you purse your lips, let the saliva collect on your mouth, before rudely spitting into his. He flinches, whimpers softly, and swallows. He looks at you with these expectant eyes, like he wants to hear how much of a good boy he is, so you do exactly that. 
You brush his bangs away lovingly. “Aren’t you just so good for me,” you purr, revel in the way his eyes flutter shut at your touch, like you could never hurt him, and you won’t. 
As sweet as the moment is, there’s a raging fire in your core begging to be stroked, and your hyperfixation on Jungkook’s mouth lets you know there’s only one way to chase the feeling. “Up,” you tell Jungkook, who whimpers sadly when you finally escape from behind him. 
But you don’t get too far, settling beside him on the bed until you’re looking at the damage you’ve caused from the front. His skin is sticky in some places, pink sheen of the lube decorating him from your incessant touching. Pants around his thighs, shirt against his chest. His face is flushed, all the way down to his chest and up to his ears, so rosy and pink all for you. He shies away under your gaze, drops his head to his chin bashfully. 
You grin, shuffle forward to turn those pretty eyes back towards you. “Messy little thing,” you tease, slotting your mouths together again. Jungkook moans this time, lazily kissing you back. His lips move in slow motion, trembling hands reaching for your face to cup, your name falling from his lips when you pull away slightly. “Need you to help me out now,” you murmur, hand on his jaw. “Can you do that, honey?” Jungkook nods hurriedly, eyes foggy and on your mouth. “Lay back.”
He does so, rushes to lay against the pillows until he’s flat on his back. You get to work on your clothes, shed your cardigan and languidly tug your top over your head in the way you know makes your breasts bounce. Beneath you, Jungkook whines at the sight. “You too,” you remind him, wiggling out of your jeans. At your instruction, he begins fumbling with his clothes, pants and underwear haphazardly thrown over the edge of the bed. 
By the time you’re naked, you’re met with a rather amusing sight. 
In his haste to take his clothing off, Jungkook seems to have gotten himself tangled in his long sleeves, shirt awkwardly bunched up around his wrists and twisted over some. You chuckle. “Help please,” he asks so politely, shaking his arms back and forth above his head. But you’re genuinely confused as to what he did, because one of the sleeves wraps around the other, pins the bulk of the fabric to his skin, and then the other wraps around that. A mess you don’t bother dissecting, simply climbing over him. He complains, of course, soft huffs you wave off. 
“Don’t need them anyway,” you shrug, can’t help the lovesick look you send him when you brush his hair away for the umpteenth time. Jungkook leans into the touch sweetly, rosy cheek pressed against your palm. “Lemme see your pretty little tongue,” you order, pussy clenching when he does as told and rolls his tongue out for you, tip pressed against his bottom lip. “Good boy.”
A soft whimper, and then you’re shuffling over him, pretty doe eyes watching with amazement when you finally hover over his face. “For me?” he asks so softly, so sweetly. 
It’s a question you’ve heard him utter countless times before in similar settings, always with a cocky grin and mean eyes, ready to send you to hell and back with his tongue or his cock. But it’s different now, big shiny eyes looking at you like you’re the greatest thing to ever happen in his life, so pliant and demure beneath your touch like he lived to serve you. 
“All for you,” you assure him, get comfortable, and slowly lower your pussy over his face. His eyes flutter shut immediately, pink tongue ready for you by the time your dripping cunt nears his face. 
You can’t help the moan that tears itself from your throat, a soft cry as he begins lapping against your folds. He’s so tender, so careful. It drives you crazy. Hands above his head squirming as you slowly grind your pussy over his face, more mindful than usual because he was so delicate tonight, like a baby bird that shivers with the simplest touch. 
His tongue is smooth, circles around your clit. He nudges your bundle of nerves back and forth a few times, sends an initial wave of tingles down your spine, before taking it between puckered lips. His slurps it into his mouth, where it’s so hot and wet, it makes your grind stutter. “Oh,” you pant, reaching down to tangle your fingers in his hair. “P-Perfect,” you mumble. 
The praise makes his features twist up cutely, mouth desperate to get more out of you. “You like that?” you gasp, holding his head still as he runs his tongue along your folds. Jungkook nods, eyes glazed over as he messily begins eating you out. “Like when I tell you you’re a good boy, Jungkookie?” 
He lets out a broken whine, the vibrations shooting up your spine and making you shiver. Tongue pressed in at your entrance, prods gently like it’s his first time (it’s not) and he’s gauging your reactions. “Oh baby,” you shudder, fingers tightening in his curls. 
He looks like an angel beneath you like this, halo of curls artfully splayed across the sheets, arms knotted above his head. Big pretty eyes that make you want to lay down and be his bitch instead, their power just so strong even when he’s whining and whimpering against your pussy like this. His tongue dips into your cunt, makes you buck against him by accident. “I’m sorry, angel,” you breathe, so caught up in your thoughts that the name just slips. It makes Jungkook’s cheeks flush a pretty pink, arms tug at their makeshift restraints. But his brain is scattered, torn between releasing himself, eating you out, and being shy. 
He settles soon enough, ends up just sticking his tongue out flat for you to grind against, using the grip in his curls to drag your pussy over his face. His scalp feels warm, sweat clinging to his hairline. He sighs endearingly against you, and it’s that final puff of warm air against your folds that has you coming, cum dripping over his lips and chin sinfully. 
When you finish, you quickly get off of him, lay down beside him. Jungkook is panting softly, tongue peeking out to taste the cum that splattered against the corner of his lips. “You were so good for me,” you praise, idly dragging your finger across his skin, collecting your cum on the tip. 
Jungkook looks at you with a heavy gaze, knotted wrists slowly returning to rest over his abdomen. “Can you… Can you call me that again?” he asks hesitantly, so shy and polite. 
“Hm?” you ask. “Angel?” His lips part, an awfully aroused look crossing his features. You smile, press your cum loaded finger against his lips and he opens, sucks around your finger and moans. “My pretty little angel,” you purr, slowly thrusting your finger in and out of his mouth. Before you can stop yourself, you’re leaning over to kiss him again, swallowing his cries in your desperate need to taste yourself on his tongue. Jungkook is more active this time around, daringly challenging your tongue with his before ultimately giving up, languidly following the pace you set for the kiss. You pull off with a pop, leave him dazed and trailing after your mouth cutely. 
You pat his cheek once, offer him a tender smile, before moving to get up and clean up. Jungkook whines at your departure, and it’s only once you’ve sat up that you realize why. 
Half hard cock at his hip, fattening slowly but surely. Instantly, it’s like the post-orgasm fatigue is yanked away, pussy throbbing at the sight of your angel and his cock, swelling from eating you out and kissing. He was too good to be true. 
“Oh, you poor thing,” you sigh dramatically, shifting onto your knees at his hip to look at him. Something pokes your leg; it’s the stupid iPad playing his dorky YouTube videos that you click off and chuck to the other side of the bed. You had had enough of that by now. 
He’s not at full mast yet, and he’s not getting there quick enough for your liking. So you take matters into your own hands. (Besides, what was stopping you tonight? Certainly not this soft, pliant Jungkook.)
Kneeling between his legs, you reach for the forgotten bottle of lube, squirt a fat glob into your hands, then decide that isn’t enough and squirt it directly onto your chest. Jungkook watches with wide eyes, lower lip caught between his teeth. “What— What’re you doing?” he stammers, can’t even sit up with his hands held together. “__, y-you don’t have—“
Squeezing your breasts together, you slip his cock between the crevice, watch as his angry head comes out on the other side so easily, so slippery. Oh, this was gonna be post-work, shower-time, spank bank material for months. 
Jungkook sobs, loud and unfiltered at the sight, expression torn as he watches you slowly work your tightened breasts down his quickly hardening member. “T-Too much, too much,” he cries, squirming and bucking beneath you. “I-I’ll come—” 
“Don’t,” you snap, stilling your moments to flick your eyes back to him. His head is rolled back, jaw strained, but when he manages to lift it up and look down at you, there’s tears that streak his cute face, trails that glisten when the lowlight of the lamp hits him just right. “Don’t fucking come yet, Jungkook.”
He sniffles weakly, more tears spilling from his eyes. “But I— it feels,” he blubbers, knotted hands reaching down for the base of his cock. You slap it away. “___, please,” he wails, face flushed from all his conflicting emotions. 
Ignoring his cries, you get back to work, moving your upper body to and fro to simulate the thrusting motion he is too weak to do himself. He whimpers pitifully, more tears leaving his eyes when you lean down and spit on the head of his cock when it emerges next, make it join the rest of the ungodly fluids painting your chest. Honestly, you’re certain it’s that damned strawberry flavored, sensation warming, edible lube that makes this experience so enjoyable, so mind-blowing. 
Jungkook seems to agree, stuttering out a messy whine. “Feels weird,” he snivels, only to be cut off when you release him from in between your tits. Immediately, he begins lamenting the loss. 
Slowly, you ease him back in. You’re beginning to understand the intensity of that damned warming lube, because with each glide of his cock between your breasts, it’s like a tingle of nerves sparks within you, insides folding in on themselves as they channel all their energy to that one area of hastily spread lube. It feels so good and wet and messy, Jungkook’s whiny sniffles only fueling the experience. His cock twitches dangerously, and you flash him a glare. “Jungkook,” you warn. 
“I’m sorry,” he weeps, thrashing back and forth as if that makes it any easier. “I just— I want,” he chokes, hips bucking into the suction you’ve created between your boobs. Tentatively, you stick your tongue out, let his tip brush against it on the next thrust. Jungkook curses, a feral groan escaping his lips. “Wanna fuck,” he seethes, “now.”
It’s but a slight peek into his regular personality, his normal mannerisms. But something about it now annoys you. In fact, it pisses you off, seeing him be so complacent and sweet just to try and overthrow you at the last second. And it’s with this same train of thought that you release him, climb over him like a crazed sex demon, and press your hand to his throat. 
“You're supposed to be good,” you spit, scowl turned on him and it immediately has Jungkook drawing back with his tail tucked, falling into line as he should. “You’re supposed to be my angel tonight, remember?”
Jungkook nods, big round eyes looking at you like you’re insane, but the cock that presses against your ass tells you that he likes it. “I-I’m sorry,” he stutters, shrinking back into the mattress. Sticky hands around his throat, probably make him warm and tingly, but all you can think about is those pretty eyes. Sensing your wavering emotions, he takes advantage by tilting his chin forward for you cutely, pink lips trembling as he silently asks for a kiss. 
You release him.
“Stupid angel,” you huff, mouth against his. “Gonna make me mad if you don’t act right,” you remind him, pushing his sweaty curls away from his face. He whimpers against your mouth, let’s you play with his hair as you calm down. He’s a blushing mess beneath you, every inch of him flushed and warm and sweaty. 
You shift back and are met with his still rock hard member against your ass. You touch him appreciatively, reaching back to stroke him with a half-assed grip. It makes him moan nonetheless, pulling away from your lips to mewl against your shoulder. “Wanna fuck?” you hum, curling your hand over the tip like he likes, watching his head roll back against his pillow at the sensation. Jungkook groans, doesn’t seem to hear you now. You try again. “Wanna fuck my pussy, baby?”
“Yes,” he gasps this time, jolts when you press the tip of your finger against the slit on his head, plug his cock from releasing any more precum. “Please, please,” he begs, the hands on his chest straining against the shirt he still hasn’t managed to shake off. 
One last kiss is delivered to him, a chaste one against his pout that makes him whine. “Whatever you want,” you purr, line him up. 
Your hands are still sticky with the lube and so is his cock. Everything is sticky; his cock, you folds, your tits, his neck. It’s a big sticky, slippery mess, but you can’t even be annoyed because everything feels so good. Your tits tingle from whatever they put in that damn lube, nipples rock hard and extra swollen today, like if you don’t touch them you’ll die. You sink back into Jungkook’s throbbing cock, and the second his cock spreads the lube along your walls, you’re jolting because it just feels so damn good. 
You can’t believe this is Jungkook’s preferred sick day treatment; YouTube, cuddles, and an ugly amount of lube. 
His cock pushes past your folds, fits snugly inside of you just like it belongs. It still feels like the first time, feels like your first day where he was so perfect and sweet. Part of you wonders what would have become of you two if he had reacted like this that day, soft and whiny, when you first prepositioned him. Maybe the sexual aspect of your relationship would be entirely different today, maybe you’d be one the always leading. 
But… you’re not sure if you’d want that. Leading is fun— hell, you’re certain this moment will be what you get engraved on your tombstone —but you were a pillow princess at heart with occasional dominant tendencies. You drool over this moment now, but if he asks for this again tomorrow you might actually bend over and die. It was a lot of work, keeping the energy going, and you find yourself having this newfound sense of respect for Jungkook as his cock slips past your folds. 
Anyway, when you sit on his cock, fingers teasingly tightening around his throat, Jungkook’s eyes are weirdly focused on your tits. He’s been doing that a lot lately, losing his mind by just staring at your tits. On some occasions he puts them in his mouth, gets possessed by some titty loving monster and sucks on them until you’re trembling. It’s fine because it’s quite frankly a huge ego boost, but something him now makes you want to pick at him for it. 
“They’re yours to taste, angel,” you hum, slowly rolling your hips over his fat cock. Jungkook whimpers, softly ruts up into your heat the next time you press down. “Tell me what you want,” you exhale, a breathy moan. 
He doesn’t say anything, just drops his mouth open for you with a trembling lower lip. Tongue peeks out, eyes glazed over in his lust, looking every bit like those hentai ads he hates so much. But you fulfill his wishes, help him sit up until he’s flush against your chest. His awkwardly bound hands get squished in the middle, and he says, “m-my hands...” 
“I’ve got you,” you soothe, undo his self-made restraints and toss them to the side. Immediately, he’s wrapping his arms around you, pulling you flush against him to latch his lips around your breasts. “S-Slow down,” you whine, hands on his biceps as he sucks your tit into his mouth, twirls his tongue around your nipple. He’s good with his tongue even when he’s sick. 
He pulls off with a pop, ragged breathing only making you more sensitive as it fans over the thin layer of saliva he leaves on your tits. “Tastes like strawberries,” he groans wondrously, head against your chest. You use the lull to get back to fucking yourself on him, but Jungkook’s got other plans. He rolls the two of you over, pins you beneath him with his hot and sweaty body. “I’m sorry,” he moans as he begins jackhammering his thrusts into you. 
Your back arches, legs thrown around his waist as the sudden change of events. “Fffuck,” you heave, “harder, angel— gotta fuck like you mean it.”
Jungkook shudders, hands looped around the small of your back. His cock rams into you over and over, each glide of it against the walls of your pussy making you unravel in his arms. His lips latch around your other boob, suck and suck like he’s expecting something to come out.
That’s when it hits you. 
“N-Nothing there,” you tell him, arms wrapped around his shoulders. His lashes are wet, eyes pinching tighter at your reminder. He pulls away almost to protest, but then you’re guiding him up to your face, hot breath mingling with yours. “Nothing there because you haven’t given me a baby yet,” you murmur darkly, watch the emotions flood his features as you tap into that taboo kink of his. 
He chokes, grinds his cock into you and holds it there. “I-I didn’t,” he sniffs, “we never— you never said,” he whines, “...you wanted one.”
You cup his face in his hands, feel slightly mean for the pride you get from his tear stricken appearance. “I do,” you purr, lazily kissing him. “Want one if it’s from you. Don’t you?” He nods like an antsy puppy, quivering against you as he slowly and shallowly ruts into you. “Don’t you wanna see me like that, angel?” you egg on, hands looping behind his neck, idly playing with stray waves and curls. “Tummy so big and swollen because you did something bad, because you couldn’t pull out.” 
Jungkook sobs, pulls you impossibly closer until the head of his cock is missing your cervix repeatedly. One of your legs is pressed nearly to your chest, hip tight from the force in which he holds you. “I-I want,” he agrees, more tears spilling down his cheeks. 
You smirk evilly, kissing the corner of his mouth gently as he slowly picks up the pace of his thrusts. “Then fuck me hard, Jungkookie,” you demand, “fuck me full of your cum.”
Jungkook nods with a sniffle against your shoulder, fingers tightening against your skin as he slowly but surely begins nailing you into the mattress. He’s a good boy, always, because he does exactly what you tell him to. Uses those bulky muscles to hold you down, makes it impossible for you to move as he pistons his hips, cock sheathing itself inside your cunt. 
Every drag makes you unconsciously clench, the raw feeling consuming your thoughts. His cock is so big and wet today, certainly due to that stupid lube from beneath his cabinet. Your entire pussy feels like it’s on ecstasy, stupidly geeked up by that lube, and you’re sure Jungkook’s cock feels the same. It makes the glide so much better, so much easier, each ram of his cock feeling so easy. “Oh, fuck,” you whimper, nails digging down his spine. Jungkook is a sobbing, sniffling mess against the crook of your neck, absolute gibberish falling from his lips. 
But you’re no better, tongue seemingly set on a chaotic rampage to validate every single one of his fantasies. “Gonna fuck me while I’m pregnant?” you pant against his ear, fingers tugging at his hair. He doesn’t offer more than a strained cry, thrusts momentarily falling out of rhythm. “You would like that, huh? Fucking me when you’re not supposed to. You’re so bad, Kook-ah,”  you gasp, eyes rolling to the back of your head. “Only pretend to be an angel but really you’re just a dirty, little pervert.” 
He wails loudly, slams his hips so hard into you that it makes you sob as well. “N-No,” he blubbers, tears against your skin. “I’m good— I’m a good boy,” he stresses, fingers bruising their prints into your skin. 
He presses so close, cock practically making your stomach bulge, but neither of you see. “Dirty angel,” you spit, yank his hair back roughly until he’s forced to look at you with that watery gaze. “So horny you’re willing to get me pregnant.”
Jungkook cries out, snaps his cock into you like he’s trying to break you in half. “No,” he heaves, tears dripping down his cheeks and onto yours. “I-I-I’d do it right,” he defends weakly, hips losing their demonic pace as his orgasm sneaks up on him. “Ma— Marry first… then, b— ba— bab—“
You swallow his words with your lips, kiss him like you’re on the verge of death in a desperate attempt to hide your tears from him. They paint your cheeks in stark strokes, trail down your skin and make everything blurry, but so does your orgasm. 
You come first, heart and body trembling at his unexpectedly sweet words, as you become a whimpering, teary mess beneath him. Jungkook follows, cries out your name one last time as he busts inside of you. 
Sticky and gross, he falls onto the pillow beside you. Poor baby is so tired, curls covering half of his face, but lips cutely puckered against the pillow. He’s sweaty as hell though, which you now vaguely remember was your original goal with all of this so you count this as a success. 
You think he’s fallen asleep, sitting up slowly and reaching for that t-shirt that bound him together earlier to clean up. He shudders when you run it against his skin, obviously still overwhelmed. You shift around the bed in search of today’s MVP. “Where’s the lube?” you mutter to yourself. 
Jungkook groans. “YouTube?” he asks, voice dry as all hell. 
“No, honey, the lube we used,” you respond, running your hands over the sheets for any signs of the pink bottle. 
“Want YouTube,” he mumbles, lets you swaddle him up in the blanket again. You roll your eyes and reach for the forgotten iPad that had long since tumbled to the floor. When it turns on, that same video from before is on pause so you don’t bother changing it as you hand it back to Jungkook. “Nice,” he murmurs, “underground water slide.”
You snort. “Weirdo.” He glares cutely, eyes barely open at this point. “Watch your YouTube.”
“Use your lube,” he sasses back softly, nonsensically, and then rather anticlimactically passes out. 
There’s something soft in your chest, something so big and overwhelming, that has you bending over his sleeping figure, mouth brushing against his. “Hurry and get better, angel,” you whisper, wish on it with all your heart. 
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 To no one’s surprise, you get sick two days later. Doyeon laughs and laughs for hours about it, tells you that’s what you get for using sex as medicine. But Jungkook’s back to normal, which means he stays over and coddles you to death. 
“Hurry and get better,” he says, spoon feeding you your famous Get Better Soon Soup that you passed on to him. “I have a question to ask you.”
There’s a little black box in his downstairs bathroom cabinet that you swear you’ve never seen, but Jungkook knows you’re lying. 
It fits perfectly. 
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epilogue
She scoffs. “And I care why?” You huff, go to scold her for their weird rivalry, but then she’s moving on. “Babe, just give him some pain relief and call it a day.”
“Fine,” you mumble. “Wait, can you look something else up for me?”
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Copyright © 2020, 1kook on tumblr. absolutely NO reposts allowed.
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feelingbluepolitics · 3 years
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"The Delta variant is much more contagious, more likely to break through protections afforded by the vaccines and may cause more severe disease than all other known versions of the virus, according to an internal presentation circulated within the Centers for Disease Control and Prevention.
..."The Delta variant is more transmissible than the viruses that cause MERS, SARS, Ebola, the common cold, the seasonal flu and smallpox, and it is as contagious as chickenpox.
..."The C.D.C. recommended that vaccinated people wear masks indoors in public settings in communities with high transmission of the virus.
"But the internal document hints that even that recommendation may not go far enough. 'Given higher transmissibility and current vaccine coverage, universal masking is essential,' the document said.
..."The agency’s data suggest that people with weak immune systems should wear masks even in places that do not have high transmission of the virus. So should vaccinated Americans who are in contact with young children, older adults, or otherwise vulnerable people.
..."The amount of virus in a person infected with Delta is a thousandfold more than what is seen in people infected with the original version of the virus, according to one recent study.
..."Infection with the Delta variant may be more likely to lead to severe illness, the document noted. Studies from Canada and Scotland found that people infected with the variant are more likely to be hospitalized, while research in Singapore indicated that they are more likely to require oxygen.
"Still, the C.D.C.’s figures show that the vaccines are highly effective in preventing serious illness, hospitalization and death in vaccinated people, experts said."
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Get Your Flu Vaccine In Singapore - Stay Protected This Season
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As the flu season approaches, safeguarding your health becomes a top priority. One of the most effective ways to protect yourself and those around you from the influenza virus is by getting a flu vaccine.
So if you are also looking to get the flu vaccine in Singapore? You landed on the right post. In Singapore, healthcare authorities and medical professionals strongly recommend getting vaccinated against the flu to reduce the risk of infection and its potential complications. For more information, visit our website.
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pilcare-nce · 26 days
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FluQuadri SH 2021 Vaccine - Inactivated influenza vaccine (Quadrivalent) - Sanofi - Pilcare - Exporter from India to Singapore
FluQuadri SH 2021 Vaccine helps protect you from influenza (flu). It works by exposing you to a small dose of dead flu virus which helps your body to develop immunity against the disease. It will not treat an existing flu virus infection.
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whattheabcxyz · 4 months
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2024-06-08
Singapore
HDB cautions property against against approaching flat sellers on HDB Flat Portal to offer their services
Former Angsana Primary School site in Tampines could be used to build 350 new HDB flats
Insurers here now covering more niche areas in mental health to stay in the game
Singaporean said to be mastermind behind Port Klang smuggling ring - the syndicate is believed to have made false declarations in customs forms to avoid tax & import fees
5-room City Vue flat in Henderson sold for $1.58m
Maritime
Shipping & port disruptions expected to delay cargo & drive up costs for businesses/consumers - due to Red Sea attacks by Houthi militia
Health
A new bird flu death is making experts uneasy
1st US case of sexually transmitted fungal infection found in New York - It's caused by the species Trichophyton mentagrophytes type VII (TMVII), a sexually transmitted form of ringworm that has spread across Europe. In 2023, France reported 13 cases of the infection, mostly in men who have sex with men.
Singapore "experts" say British Medical Journal article suggesting COVID-19 vaccines contributed to excess deaths is "unbalanced"
Literature
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^ Real-life "ghost stories" from around the world
Food
Unknown user impersonated CCK coffee shop on Google Maps & left rude feedback on customers' reviews
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Ventilation vs covid
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There's increasing medical consensus that indoor spread of covid takes place through floating aerosol particles. If your environs are warm and dry year round (like my place in San Fernando Valley) this militates a cautious shift to outdoor activities.
https://www.wired.com/story/how-masks-went-from-dont-wear-to-must-have/
But not everyone can be outdoors all the time. Some activities are necessarily indoors, while others will be shifted indoors by rain and cold (and wind, etc). There's preliminary evidence that good air filtration makes a big difference when you're inside.
Good HEPA systems for every room can cost $500+. That's a lot! Some experts, inspired by a study of improvised filters in Singapore as a means of filtering Indonesian wildfire smoke, are looking into $10 paper HEPA filters strapped to $27 box-fans.
https://www.wired.com/story/could-a-janky-jury-rigged-air-purifier-help-fight-covid-19/
These filters were found to capture 75% of  1-10μm particles! Wired's Adam Rogers talked to air-quality expert Richard Corsi from Maseeh College Engineering/Comp Sci, who started riffing on ways this design could be improved upon.
Of course, that's no magic bullet. You could improve the ventilation in your indoor spaces by opening a window, which is hard to do when it's really cold out.
As it turns out, there's one place that's really well-prepared for that exigency: New York City.
https://www.bloomberg.com/news/articles/2020-08-05/the-curious-history-of-steam-heat-and-pandemics
New York's infamously "over-indexed," sweltering steam heaters date back to the 1918 flu pandemic, when buildings were fitted with high-powered heating specifically so they could stay warm in winter, even with all their windows open to the elements (!).
That's the origin of the perennial New Yorker's lament that their apartments are turned into saunas every winter because their steam radiators have two settings: "off" and "broil."
What's more, steam radiators are basically indestructible and a LOT of New York's housing stock still uses these systems (though the boilers don't run on coal anymore).
This isn't much help to people who don't have this kind of heating, but we've already seen what happens in NYC when airborne diseases aren't confronted with sufficient vigor.
None of this is a replacement for a vaccine or therapeutic, but as harm-reduction strategies go, it's good to see this stuff enter the discourse. What's more, this is all early days, and there are probably some serious, easy gains yet to be won.
Image: Jim Rosenthal
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Link
Get all information about the 5 Things that your Baby Needs For Wellbeing and to enjoy there life properly with this blog, read out now to get every information briefly!
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Link
In mid-December, some people in the central Chinese city of Wuhan began complaining of flu and pneumonia-like symptoms. Some had a high fever. Doctors were perplexed. To find out what might be causing their illness, geneticists analyzed the DNA of the virus that had infected them. At once, the scientists realized this virus was new to science. As of January 23, experts at the World Health Organization, or WHO, in Geneva, Switzerland, estimated that at least 557 people have contracted the rapidly spreading disease. At least 17 have died.
Tedros Adhanom Ghebreyesus is Director-General of the WHO. At a January 23 news conference he said: “Make no mistake, this [disease outbreak] is an emergency in China.” Although it “has not yet become a global health emergency,” he says, “it may yet become one.”
Exercising caution before declaring an emergency makes sense, says Jennifer Nuzzo. She’s an epidemiologist, or disease detective. She works at the Johns Hopkins Center for Health Security in Baltimore, Md. Researchers are still trying to work out how infectious, and how dangerous, the virus really is, she explains. And, she adds, “I’m glad they’re taking their time.” Right now, she says, “A decision to declare an emergency will signal a level of concern that we don’t have the data to support.”
The new germ appears to be a novel coronavirus (Kuh-RO-nuh-VY-rus). One germ that can cause the common cold comes from that virus family. So do the viruses behind MERS and SARS. Both of those diseases have triggered frightening global outbreaks over the past two decades. Virus experts now worry that the new coronavirus may be poised to do the same.
Chinese researchers used genetic material from one patient to identify the new virus. The World Health Organization has given this germ the uninspired name 2019 novel coronavirus, or 2019-nCoV.
“Anytime there’s a novel virus that appears that’s causing critical illness, it merits concern,” says Amesh Adalja. “Right now, there’s no cause for panic.” An infectious disease physician, he too works at Johns Hopkins Center for Health Security.
Both Nuzzo and Adalja hope this outbreak sparks renewed interest in studying coronaviruses and in creating vaccines and treatments. “It’s been 17 years since SARS, and we still don’t have any coronavirus vaccine. We don’t have any coronavirus antivirals,” Adalja says. “The only way we can take outbreaks like these off the table is to develop countermeasures against them.”
What are the symptoms of 2019-nCoV? Who is most at risk? Who is most likely to die of it? “We don’t know a whole lot at this point,” says Jennifer Nuzzo. “It seems to be a novel coronavirus that can produce viral pneumonia,” she notes. Pneumonia is a lung infection. It can cause coughing, fever and trouble breathing.
“The confirmation that human-to-human spread with this virus is occurring in Asia certainly raises our level of concern,” says Nancy Messonnier. She directs the National Center for Immunization and Respiratory Diseases. That’s part of the U.S. Centers for Disease Control and Prevention, in Atlanta, Ga. Says Messonnier, CDC believes the risk “to the American public at large remains low at this time.”
For now, Chinese authorities are taking big efforts to slow the spread of the virus. On January 23, they locked down the city of Wuhan — home to nearly 11 million people. They halted all air, train and bus travel out of the city. Several other nearby cities also are closed. That’s a big deal as this outbreak emerged at the outset of nationwide travel for the lunar New Year on January 25. That’s when people throughout China get together to celebrate with friends and family.
Elsewhere throughout the world, many airports that receive a lot of visitors from China have stepped up their screening of arriving passengers.
Infected patients seen far from Wuhan
Cases of the new disease have been reported in people who had traveled from the Chinese mainland to Singapore, Taiwan, Thailand, Japan and South Korea. On January 21, the CDC also confirmed the first case of the disease in the United States. A man had returned home to the United States from Wuhan six days earlier. When he sought treatment at a hospital in Washington state, the staff collected a sample from the patient. They sent it to the CDC. The agency used PCR technology to analyze DNA from the sample. This confirmed it was the same virus now spreading through China.
Scientists are now trying to understand how dangerous the virus is. How sick most of the infected people become also is unclear. So far, details about the condition of patients in China have not been widely shared, says Adalja. For instance, “Are they requiring oxygen therapy? Intravenous fluids? Those types of questions are really important in helping us know where to place this outbreak in terms of risk.”
Also unclear, Nuzzo says, is exactly how the virus spreads. “Can a sick person easily transmit the disease when they’re out in the community? Or can it only be transmitted in risky situations, for example, when a health care worker is caring for a patient and their personal protective equipment fails?”
And one of the biggest questions: Where did the disease come from? The suspicion is it came from some animal. Many times, animals can harbor a virus without themselves becoming sick. Did that happen here?
The first people reported to have 2019-nCoV became sick after visiting a Wuhan seafood market. But it didn’t just sell fish and shellfish. It also sold a number of wild animals, such as wolves, as food. Might one such animal be the source?
A more provocative suggestion is that the virus came from snakes.
On January 22, the Journal of Medical Virology published a paper suggesting that the germ’s DNA appears to be a mishmash of a known bat coronavirus and another coronavirus that is unknown. In this paper, researchers from four Chinese research centers reported that “snake is the most probable wildlife animal reservoir for the 2019‐nCoV.” They based it on snake genetic material. They conclude, there may have been “cross-species transmission from snake to humans.”
But some virus experts dispute that conclusion. “You should be massively skeptical of a snake” as the source, says Edward Holmes. He’s a virologist in Australia at the University of Sydney. Indeed, he challenges what the authors make of their new analysis. “Their own data doesn’t support their conclusions,” he charges.
“I can’t categorically say it’s never happened” — the transmission of a virus from a snake to humans. After all, he notes, “I don’t know every virus. But the reservoirs for human viruses are mainly mammals and maybe birds.” As such, he suspects, “it’s most likely that the reservoir host of that virus is a bat, given where it [its genome] falls on the evolutionary tree.” Certainly, he says, “It’s close to bat viruses.”
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nickylovesrefugees · 5 years
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Coronavirus myths and facts
I am writing this as a doctor with an interest in infectious diseases who is currently studying a masters of international public health. Myths and facts about COVID-19. Please share if you think this is worthwhile. References in link at the end.
MYTHS
Myth: “COVID-19 is just like getting the flu”
COVID-19 is not just like the flu! The symptoms are often similar, that’s true. But there are key differences:
Influenza
Mortality: 0.1%
Vaccine availability: Vaccine updated yearly
Scientific understanding: Excellent
R0: 1.2
COVID-19
Mortality: ~3%
Vaccine availability: Does not exist
Scientific understanding: Limited, highly unpredictable
R0:2-4
Note: R0 is the number of people that the average infected person then goes on to infect
So essentially - coronavirus is much more contagious, is many times more deadly, there’s no vaccine and it’s highly unpredictable.
Myth: “Coronavirus is killed by warm weather”
I saw this floating around in a chain email purportedly from “Stanford University”, which claimed that a temperature of 26 degrees would kill the virus. There is no evidence to suggest this. If this were the case, the virus would die inside our bodies (~36 degrees) and nobody would get sick… It is important to note also that the WHO points out that cold weather similarly does not kill the virus.
Myth: “Drinking warm water kills viruses”
Nope. Water doesn’t have any toxic effects, and warming it slightly doesn’t change that. Even if it did, the virus is in your airways, not your stomach.
Myth: “If you have a runny nose, you cannot have COVID-19”
Another ridiculous claim. In general, in medicine, never/always statements are rarely correct, especially when looking at symptoms. There are always variations in symptoms between different people in the real world.
Myth: “Hand sanitiser is better than soap and water”
False. It’s the other way around. Soap breaks down the fatty bilayer which forms the “envelope” or wall of the viral particle. It does this in a similar way to ethanol-based handwashes, but most commercial hand sanitisers have a lower ethanol content and are not as effective. To be effective against coronavirus, your hand sanitiser should have at least a 60% ethanol content.
Myth: “I’m young and healthy, if I get coronavirus I’ll be fine”
Many young people who get COVID-19 will suffer a flu-like illness and not need hospitalisation but there’s also strong evidence that young healthy people can also get very sick with COVID-19. For example, more than 50% of patients admitted to ICU in France were under 60.
Myth: “If you can hold your breath for ten seconds without coughing, you cannot have COVID-19”
If it were that easy to diagnose coronavirus, the hospital and GP system would be under a whole lot less pressure. Once again, these simple, “too good to be true” claims are exactly that.
Myth: “Antibiotics can treat COVID-19”
Antibiotics have no activity against viruses - they are used exclusively for bacteria. Occasionally, very unwell people with COVID-19 may develop superimposed bacterial infections in hospital, and is this setting antibiotics will be used. But this is to treat the bacterial pneumonia, not the COVID-19 infection. Currently, there are no WHO-recommended medications to treat COVID-19, although reports are coming out of some countries that some antivirals usually used in treatment of hepatitis or HIV may be beneficial.
FACTS
Fact: Ibuprofen should be avoided in patients with COVID-19.
Ibuprofen, sold under brand names such as nurofen or advil, is an NSAID (non-steroidal anti-inflammatory drug). It’s used for a variety of inflammatory conditions, and is also sometimes used for fever that is not responding to paracetamol. However, a paper was published on March 11 in the Lancet linking increased ACE2 levels (an enzyme that coronaviruses use to bind to target cells) with COVID-19 infection. This is relevant because ibuprofen can increase levels of ACE2, at least in rats. More research is needed in this area, but for now the WHO has recommended avoiding ibuprofenin COVID-19, and instead using paracetamol. This also implies that theremay be an argument for withholding ACE-Inhibitors (a common blood pressure medication) but the European Society of Cardiology recommends that they are continued.
Fact: Healthcare workers on the front line are doing their absolute best in a very difficult time.
Many of my best friends are working on the front lines as junior doctors, GPs, emergency or medical registrars, nurses, pharmacists and other allied health professions. They are doing their best, but the situation is constantly evolving, and guidelines continue to do change. As such, they may not test you for COVID-19 when you are expecting a test, or otherwise treat you in some way that differs from your expectations. Rest assured that they are working very hard to keep up to date, and to behave in a manner that prioritises not only your health, but also public health and the best possible allocation of resources. Please be patient and honest with, and kind to, them in these challenging times. Speaking as one of them, we really do care about you.
Fact: Panic buying deprives vulnerable people of vital necessities, and is completely unnecessary.
I’ve touched on this earlier, but please do not hoard groceries. Many elderly or people with disabilities do not have the luxury or option of visiting multiple stores, so if they go to a supermarket that has had its shelves cleared out, they have no backup option and may be forced to go without. If everyone were to return to how they shopped a month ago, everyone would have enough food!! The supermarkets never run out of pasta or toilet paper normally, and they will stop running out if people just shop normally. The supermarkets are not going to close, there is no need to hoard food.
Fact: We still have a lot of control over what happens over the next few weeks.
Here, we must learn from the examples of other countries. If we continue to treat COVID-19 with the same cavalier attitude, continuing to attend large events, public places like gyms, churches etc, we will follow in the footsteps of Italy, which now has over 30,000 cases and over 2,500 dead. The death toll there is now climbing by hundreds per day. On the other hand, a combination of widespread closures and shutdown measures, combined with individuals taking responsibility to do their absolute best, will see us closer to countries like Singapore or South Korea, which have dramatically curbed their cases.
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Fact: Social distancing will save lives.
Social distancing will dramatically reduce coronavirus spread. This works both because undiagnosed cases of COVID-19 have less opportunity to spread, and because uninfected people have less opportunity to encounter coronavirus as you go about your life. So please take it seriously, even if you are feeling perfectly well. Stay home unless it is absolutely essential that you leave the house. Wash your hands often, with soap and water. Avoid touching your face.
In summary, we need to make informed, evidence-based decisions to combat this pandemic. It poses grave public health risks if not taken seriously, but we can do a lot to mitigate these risks. This needs to be led by Government, but in the absence of decisive leadership there, we must take the lead ourselves. But our response needs to be one that continues to look after the needs of our most vulnerable members of the community.
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Problems with a government-created coronavirus test have limited the United States’ capacity to rapidly increase testing, just as the outbreak has entered a worrisome new phase in countries worldwide. Experts are increasingly concerned that the small number of U.S. cases may be a reflection of limited testing, not of the virus’s spread.
While South Korea has run more than 35,000 coronavirus tests, the United States has tested only 426 people, not including people who returned on evacuation flights. Only about a dozen state and local laboratories can now run tests outside of the Centers for Disease Control and Prevention in Atlanta because the CDC kits sent out nationwide earlier this month included a faulty component.
U.S. guidelines recommend testing for a very narrow group of people — those who display respiratory symptoms and have recently traveled to China or had close contact with an infected person.
But many public health experts think that in light of evidence that the disease has taken root and spread in Iran, Italy, Singapore and South Korea, it’s time to broaden testing in the United States. Infectious disease experts fear that aside from the 14 cases picked up by public health surveillance, there may be other cases, undetected, mixed in with those of colds and flu. What scares experts the most is that the virus is beginning to spread in countries outside China, but no one knows whether that’s the case in the United States, because they aren’t checking.
“Coronavirus testing kits have not been widely distributed to our hospitals and public health labs. Those without these kits must send samples all the way to Atlanta, rather than testing them on site, wasting precious time as the virus spreads,” said Senate Minority Leader Charles E. Schumer (D-N.Y.).
In a congressional hearing Tuesday, Sen. Patty Murray (D-Wash.) pressed Health and Human Services Secretary Alex Azar on whether the CDC test was faulty. He denied that the test did not work.
But in a news briefing that was going on about the same time, Nancy Messonnier, director of the CDC’s National Center for Immunization and Respiratory Diseases, said that she was “frustrated” about problems with the test kits and that the CDC hoped to send out a new version to state and local health departments soon.
“I think we are close,” she said. She said that the agency is working as fast as possible on the tests, but that the priority is making sure they are accurate.
Currently, she said, a dozen state and local health departments can do the testing, although positive results need to be confirmed by the CDC. She also said she hoped that tests from commercial labs would soon come online.
Messonnier said the agency was weighing widening its testing protocols to include people traveling to the United States from countries beyond mainland China, considering the rapid spread of the virus in other places in recent days.
The nation’s public health laboratories, exasperated by the malfunctioning tests in the face of a global public health emergency, have taken the unusual step of appealing to the Food and Drug Administration for permission to develop and use their own tests. In Hawaii, authorities are so alarmed about the lack of testing ability that they requested permission from the CDC to use tests from Japan. A medical director at a hospital laboratory in Boston is developing an in-house test, but is frustrated that his laboratory won’t be able to use it without going through an onerous and time-consuming review process, even if demand surges.
“This is an extraordinary request, but this is an extraordinary time,” said Scott Becker, the chief executive of the Association of Public Health Laboratories, which is asking the FDA for permission to allow the laboratories to create and implement their own laboratory-developed tests.
At one hospital in the Mid-Atlantic region, a patient who recently returned from Singapore, which has 90 cases, was admitted to the hospital with mild upper respiratory symptoms, according to a hospital official who spoke on the condition of anonymity to protect the patient’s privacy. The patient tested negative for flu. Because of underlying medical conditions, the person was at higher risk for severe illness if this was a coronavirus infection.
Even though clinicians suspected coronavirus, and treated the person for it and placed the patient in isolation, the patient was not tested.
“If this person had returned from mainland China, they would have been tested for coronavirus,” the official said. The patient recovered and was discharged to their home.
Testing also affects other aspects of care.
People with confirmed cases can enroll in clinical trials for therapeutics. For patients who need more intense care in a facility with a biocontainment unit, that facility can receive reimbursement from the federal government for care, the official said.
The CDC announced a week and a half ago that it would add pilot coronavirus testing to its flu surveillance network in five cities, a step toward expanded testing of people with respiratory symptoms who didn’t have other obvious risk factors. Specimens that test negative for flu will be tested for coronavirus. But that expanded testing has been delayed because of an unspecified problem with one of the compounds used in the CDC test. About half of state labs got inconclusive results when using the compound, so the CDC said it would make a new version and redistribute it.
To public health experts, the delays — and lack of transparency about what, exactly, is wrong with the test — are extremely concerning.
“We have over 700 flights every month between Hawaii and Japan or South Korea,” where the virus is spreading in the community, said Hawaii Lt. Gov. Josh Green, who is also an emergency physician. It’s unlikely that the CDC would allow state labs to accept a test from another nation, he said, but “this is an exceptional circumstance.”
In a letter to the FDA, the Association of Public Health Laboratories, which represents state and local laboratories, asked the agency to use “enforcement discretion” to allow the laboratories to create and use their own laboratory-developed tests.
“While we appreciate the many efforts underway at CDC to provide a diagnostic assay to our member labs … this has proven challenging and we find ourselves in a situation that requires a quicker local response,” said the letter, which was co-signed by Becker. “We are now many weeks into the response with still no diagnostic or surveillance test available outside of CDC for the vast majority of our member laboratories.”
Because a public health emergency has been declared, certified hospital laboratories that usually have the ability to internally develop and validate their own tests can’t use them without applying for an “emergency use authorization,” a major barrier to deploying the test.
“I think a lot of people, myself included, think it’s very likely this virus might be circulating at low levels in the United States right now. We can’t know for sure because we haven’t seen it,” said Michael Mina, associate medical director of clinical microbiology at Brigham and Women’s Hospital. He said the optimal testing scenario for flu is a 30-minute turnaround on a test, but right now, shipping samples to Atlanta to test for coronavirus means a 48-hour wait.
“A lot of hospitals are trying to do something similar, which is get a test up and running on an instrument, get it validated in-house,” Mina said. “I think all of us are coming to the same realization that we can’t do anything as long as this remains under the control of CDC and state labs.”
Marion Koopmans, a virologist at the Erasmus University Medical Center in the Netherlands, which has performed a few hundred tests on behalf of more than a dozen countries, said that developing a test for a new pathogen is complicated and involves refinement and a back-and-forth between researchers who are constantly learning from one another.
“That is typical for a new disease outbreak. No one actually knows how this works, so you really have to build these assays on the fly,” Koopmans said.
But as the United States is still struggling to ramp up its capacity, the coronavirus test was added to the sentinel flu surveillance system in the Netherlands two weeks ago. The test was recently rolled out to 12 high-performing molecular diagnostic laboratories in the Netherlands so that they can be ready to scale up if demand increases.
Part of the problem in the United States is the tension between regulations intended to ensure a high-quality standard for tests and the need to roll out diagnostic capabilities very quickly. No test is perfect, and with high stakes for missing or misidentifying a case, public health officials want to make sure that tests are as accurate as possible and are validated by labs that run them. But the slowness may also reflect years of underinvestment in public health infrastructure — and a bias toward developing treatments that may seem more appealing to the public.
“The public health system is not sufficiently built to surge very rapidly,” said Luciana Borio, the former director of Medical and Biodefense Preparedness Policy at the National Security Council and now a vice president at In-Q-Tel, a strategic investor that supports the U.S. intelligence community. “Over the years, when given limited dollars, we applied it toward vaccines and therapeutics, more so than diagnostic tests. I think there’s this idea: The diagnostic test is not going to save my life. But the fact is they underpin so much of the response and deserve a lot more attention.”
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