#National Institute of Allergy and Infectious Diseases (NIAID)

[justinspoliticalcorner]

Lee Moran at HuffPost:

Then-President Donald Trump unloaded about Joe Biden and bombastically predicted he would beat his 2020 rival in a landslide in his expletive-laden last conversation with Dr. Anthony Fauci, the former longtime director of the National Institute of Allergy and Infectious Diseases revealed in his memoir.

Trump called Fauci from Air Force One on Nov. 1, 2020 — just two days before the election — in “what turned out to be” their final exchange, Fauci wrote in “On Call: A Doctor’s Journey in Public Service,” which debuted Tuesday. The Daily Beast and The New York Times shared excerpts from the book. Trump reportedly boasted to Fauci: “I am going to win this election by a fucking landslide. Just wait and see. I always did things my way. And I always win, no matter what all these other fucking people think. And that fucker Biden. He is so fucking stupid. I am going to kick his fucking ass in this election.” Trump lost the election, but continues to falsely claim it was stolen from him. Fauci served as chief medical adviser to the Biden White House until his retirement in 2022.

[...] Fauci also recalled his “first experience” of bearing the brunt of Trump’s rage during a call on June 3, 2020, when the then-president “started screaming at me” for correctly predicting immunity to coronavirus from vaccines would probably last six months to a year. Trump was furious by the implication that booster shots would likely be required after the administration of initial vaccines, which had yet to be rolled out.

Former NIAID head Dr. Anthony Fauci recounts in his newest memoir On Call: A Doctor’s Journey In Public Service that Donald Trump called Joe Biden “that fucker Biden” 2 days before the 2020 general elections and boasted about he was “going to win this election”.

From the 06.17.2024 edition of MSNBC's The Rachel Maddow Show:

[xtruss]

We're Having A COVID Summer Surge. Should You Get The Updated Vaccines Now?

The FDA Just Approved an Updated Vaccines, and Officials Say Paxlovid is Still Effective in Preventing Severe Cases.

— By Sanjay Mishra | August 22, 2024

A Colorized Ccanning Electron Micrograph of a Cell (Blue) Infected with the Omicron Strain of the SARS-CoV-2 virus (Yellow). Micrograph By National Institute of Allergy and Infectious Diseases (NIAID)/National Institutes Of Health/Science Photo Library

The summer of 2024—the fifth since the COVID-19 pandemic began—is projected to be the biggest summer wave of COVID infections to date.

Since early May, COVID infections have steadily increased in the United States, Europe, Singapore, New Zealand, and Australia. The U.S. Centers for Disease Control and Prevention estimates that COVID-19 infections are currently increasing in 25 states based on data from emergency department visits. However, hospitalizations and deaths from COVID remain at their lowest levels.

Now, the U.S. Food and Drug Administration has approved updated vaccines to protect against current variants of the virus.

This recent surge has been driven mainly by a new group of closely related Covid subvariants, known collectively as "FLiRT."

As the summer winds down, students across the U.S. will return to school. Traditionally, this also coincides with the season of respiratory viruses, such as flu, RSV, and increasingly COVID.

"Not sure what will happen this fall and winter," says Kei Sato, a virologist at the University of Tokyo. While the FLiRT variants are likely to keep evolving after summer, entirely new subvariants cannot be ruled out. "An Omicron-like event” seems to have occurred every year in the fall since 2021, says Sato.

Here's what you need to know about the new variants and the new vaccines.

What Are FLiRT Variants?

The "FLiRT" variant family includes the majority of currently circulating variants, identified with the letters KP, JN, and the variant LB.1.

The unofficial name "FLiRT" is an acronym for a set of mutations on the spike protein of SARS-CoV-2, the virus that causes COVID-19. The virus uses spike protein to bind with ACE2 receptors in our nose and lung cells to cause infection.

All proteins are made up of amino acids that string together like beads. Mutations can change one amino acid to another, thereby altering the behavior of the protein and making the virus more or less infectious, or able to dodge immunity.

The FLiRT subvariant family members are descended from the JN.1 variant that was dominant in the U.S. in early 2024. JN.1 itself was highly unusual because it acquired 41 mutations that differentiated it from Omicron XBB.1.5, which is the variant upon which the current bivalent COVID booster is based.

Should You Get The New Vaccines?

The two updated mRNA vaccines, manufactured by Pfizer-BioNTech and Moderna, target a FLiRT variant called KP.2. Anyone over the age of 12 can get the new shots, as long as they haven't received a booster in the last two months.

“Vaccination continues to be the cornerstone of COVID-19 prevention,” Peter Marks, director of the FDA’s Center for Biologics Evaluation and Research said in a statement.

Another vaccine targeting the variant JN.1 and manufactured by Novovax is also under review and could be approved soon.

Previous research also showed that older vaccines based on XBB.1.5, an earlier subvariant of Omicron, were still effective in preventing severe COVID-19. While this vaccine produces antibodies that still target the FLiRT variants, the efficiency is notably reduced. A recent infection from the JN.1 variant also seems to provide strong protection against all the FLiRT variants.

That said, the CDC recommends that everyone six months and older get a COVID vaccine. Those at high risk for serious COVID-19 should get vaccinated with the most recent versions available.

How Alarming Are FLiRT Variants?

Coronaviruses, such as SARS-CoV-2, frequently mutate to avoid recognition by antibodies. The two FLiRT mutations remove the sites on the virus where antibodies bind the SARS-CoV-2 virus.

Additional mutations on the FLiRT variants can either help the virus bind more efficiently to ACE2 receptors making it more infectious, help it evade previous immunity, or both, says Adrian Esterman, an epidemiologist at the University of South Australia, Allied Health & Human Performance in Adelaide, Australia

Early studies show that all existing FLiRT subvariants are very good at dodging previous immunity acquired through multiple COVID vaccinations—including the most recent COVID bivalent booster—or a breakthrough infection from a previous strain of Omicron.

But the good news is that by escaping the antibodies, the FLiRT variants have also seem to lost some ability to infect their target because the virus needed the original antibody-binding sites to bind the ACE2 receptor and enter cells.

"These variants are not yet particularly concerning, even with the new mutations that affect certain aspects of the virus's biology," says Shan-Lu Liu, a virologist at the Ohio State University.

It is common for viruses to acquire mutations that help them dodge immunity, which can affect their ability to infect cells, says Liu. "The viruses can quickly evolve new mutations to restore their infectivity."

But in the meantime, Sato thinks that waning immunity from previous vaccinations and infections, coupled with the FLiRT variant's ability to dodge remaining immunity, are probably the main reason for the recent surge in infections.

Liu also agrees that the currently rising numbers of COVID infections are mostly due to low booster uptake and increased summer travel.

Are COVID Medicines Still Effective?

Emergency department visits, hospitalizations, and deaths have all spiked during this summer but are still much lower compared to earlier waves of the pandemic.

There is no indication that these new FLiRT variants are more dangerous than other Omicron strains.

A study shows that Paxlovid is still effective against FLiRT variants. Other antiviral drugs such as molnupiravir and remdesivir are also expected to work since their mechanism of action is not affected by mutations in the spike protein.

[reportwire]

CHOP Researchers Identify Molecules that Optimize Immune Presentation of Antigens across the Human Population

Newswise — Philadelphia, February 24, 2023—Researchers at Children’s Hospital of Philadelphia (CHOP) have identified variants of a chaperone molecule that optimizes the binding and presentation of foreign antigens across the human population, which could open the door to numerous applications where robust presentation to the immune system is important, including cell therapy and immunization. The…

[reality-detective]

Think Fauci torturing and killing dogs is bad? Wait till you learn what he did to orphaned kids in NYC for HIV "research".

In New York’s Washington Heights is a 4-story brick building called Incarnation Children’s Center (ICC). This former convent houses a revolving stable of children who’ve been removed from their own homes by the Agency for Child Services. These children are black, Hispanic and poor. Many of their mothers had a history of drug abuse and have died. Once taken into ICC, the children become subjects of drug trials sponsored by NIAID (National Institute of Allergies and Infectious Disease, a division of the NIH), NICHD (the National Institute of Child Health and Human Development) in conjunction with some of the world’s largest pharmaceutical companies – GlaxoSmithKline, Pfizer, Genentech, Chiron/Biocine and others.

I have seen and saved a couple of photos, but I can't post them here. It would be grounds for me to be instantly deactivated. What these soulless entities have done to children is beyond evil‼️ And that's putting it mildly 🤔

[darkmaga-retard]

The discovery of a contract awarded by the U.S. Department of Defense to Labyrinth Global Health for “COVID-19 Research” in November 2019 has raised questions about the permanent U.S. Government’s knowledge of the novel coronavirus.

But the findings also suggest the permanent U.S. Government may have had a hand in the creation of this alleged virus in Biolabs through Gain of Function Research overseen by Dr Anthony Fauci.

This would explain why they knew the name of the novel coronavirus disease three months prior to the World Health Organization officially naming it Covid-19 in February 2020.

And it may also explain why Moderna and Fauci’s National Institute of Allergy and Infectious Diseases (NIAID) had a confidentiality agreement for an mRNA Coronavirus vaccine candidate in early December 2019, which was developed and jointly owned by Moderna and Fauci’s NIAID.

[evoldir]

Fwd: Research Technician Job: UConnecticut.ResTechAnimalCare

Begin forwarded message: > From: evoldir@evol.biology.mcmaster.ca > Subject: Research Technician Job: UConnecticut.ResTechAnimalCare > Date: 6 September 2024 at 06:47:34 BST > To: rdmpage@gmail.com > > > The University of Connecticut is searching for a full-time lab research > technician, to work in Dr. Daniel Bolnick’s lab group in the Department > of Ecology and Evolutionary Biology, on the evolutionary genetics of > fish immunity to tapeworm parasites. > > The primary responsibility of the technician will be to run the lab’s > fish colony of threespine stickleback. Secondary responsibilities include > assisting with laboratory experiments, and lab management tasks. This > position is funded by a National Institute of Allergy and Infectious > Disease (NIAID) grant to map the genetic basis of differences in immunity > between natural populations of fish, and differences in immune suppression > between populations of tapeworm parasites. > > Tasks: Animal colony management includes feeding fish, aquarium system > maintenance, monitoring fish health, record keeping, and breeding lab > animals. The technician will also supervise and coordinate other lab > members who contribute fish care help. Secondary responsibilities > related to the fish colony will be to collaborate with lab members > doing laboratory experiments (e.g., vaccination assays) and associated > laboratory work. In addition the technician will help with general lab > management including purchasing lab supplies for lab members, ensuring > safety compliance, and helping to keep the lab organized. > > Minimum Qualifications: Applicants must be have an undergraduate degree > (BSc or BA) in biology or a related field. They must be organized and > reliable and have the ability to carry out independent laboratory research > and fish care protocols after initial training. Previous educational > experience and work records should demonstrate a good work ethic, > organizational ability, and interest in scientific research. > > Preferred Qualifications: Experience with animal care is strongly > preferred. Prior experience with care of fish or other aquatic organisms > is especially valuable. Some prior experience with laboratory research > such as (but not limited to) molecular genetics, immunology, or cell > biology, is helpful but not required. > > Start date and duration: The position is available to begin as early > as September 16, and we would prefer candidates who could begin before > October 1. The position will begin with a one year appointment subject > to renewal for up to four years. The position might be extended for > additional years beyond four, if additional grants are funded. > > Salary is expected to be between $38,000-$45,000 per year depending > on qualifications. > > Applicants should electronically submit a single pdf file containing the > following in order: > > 1.        Cover letter (1 – 2 pages), including summary of relevant >          job experience, research experience, career goals, and how >          this position fits your career plans. > > 2.        CV > > 3.        List of two (or three?) references, with contact information >          (email, telephone and mailing address) > > We will request letters directly from these references, after identifying > top candidates. > > The application pdf file should be emailed to Dr. Daniel Bolnick > (daniel.bolnick@uconn.edu). Include the subject line “Fish Care > Technician Application:

[bighermie]

Fauci Stepping Down as Head of NIAID After 40 Years

Fauci Stepping Down as Head of NIAID After 40 Years https://link.theepochtimes.com/mkt_app/fauci-steps-down-as-head-of-niaid-after-40-years_4955643.html?utm_source=andshare

Prosecute the fucker

[wibble-wobbegong]

richard henry creel is really such a character. Such a character.

so, quick summary, in one of the newspaper articles there’s a mention of someone names richard brenner

found by @aemiron-main

richard brenner is listed as the head of the Narcotic Enforcement Division from 1954-1971

richard henry creel is the son of virginia fackle creel and henry clay creel. im sure the connection is obvious

anyway, when we look into who this richard henry creel guy was, we learn that he was the assistant surgeon general of the U.S. public health service, and to become this head he’d have to have had specialized training or significant experience in public health. so, this guy was heavily involved in this stuff, though his exact service starts in 1921 but the end is never specified

under the PHS, the, “The Division of Venereal Diseases was established in 1918, and the Narcotics Division in 1929 (it eventually became the National Institute of Mental Health).”

now, richard henry creel was born in 1878 — he would’ve been in his 50’s by the time the narcotics division was actually created

1955 - “The National Microbiological Institute became the National Institute of Allergy and Infectious Diseases (NIAID) by order of the Surgeon General on December 29. The Biologics Control Laboratory was detached from the institute and expanded to division status within NIH.”

1957 - “The Center for Aging Research was established November 27 as the focal center for NIH extramural activities in gerontology.”

1958 - “On July 16 the Division of General Medical Sciences was established by order of the Surgeon General, extending research into noncategorical areas covered until that time by the Division of Research Grants. The Center for Aging Research was transferred from the National Heart Institute to the Division of General Medical Sciences on November 4.”

1962 - “Five acres of land for a Gerontology Research Center were donated by the City of Baltimore in December.”

1963 - “The National Institute of Child Health and Human Development and the National Institute of General Medical Sciences were established on January 30. The Center for Research in Child Health and the Center for Research in Aging (established in 1956) were transferred from NIGMS to NICHD.”

1967 - “The National Institute of Mental Health [narcotics division] was separated from NIH and raised to bureau status in PHS by a reorganization that became effective January 1.“

1971 - “The White House Conference on Aging recommended creating a separate National Institute on Aging on December 2.”

source

now that’s a lot of words and moving and bullshit, so here’s the most important stuff to know.

richard henry creel was appointed assistant general surgeon in 1921, and 8 years later the Narcotics Division was formed. the surgeon general he was serving served from 1920 to 1936 — it isn’t much of a reach to say he was probably involved in the creation of this division

now, richard brenner was supposedly the head of the Narcotics Enforcement Division from 1954 to 1971. during that time, the narcotics division was brought up to bureau status, putting it at rank with programs like the FBI and an entire institute dedicated to researching the effects of aging were created, merging aging research with child health research

all of this stuff has roots in the PHS, and the PHS’ biggest start up was chemical research. all of this gets rooted back to chemical research

so, when we look at it, we can see that the same year the institute on aging was created, richard brenner was resigned and richard creel died. this was the year that all the main kids were born, most importantly el and will

i’d also like to point out the center of aging stuff began about two years before henry was taken by brenner. that would be when henry was 10, and i believe that that was the year henry moved to hawkins (trust in @laozuspo) and it was only a year after richard brenner had gotten involved with the narcotics division

what could this all be pointing to? well, both em and james have been feeding me stuff about henry’s regeneration abilities. more importantly, how they resemble cancer. what i didn’t include in the info from 1955 is that the first ever cancer chemotherapy center was established — the same year the Biologics Control Laboratory was given its own division. the BCL explored viral diseases and produced vaccines. the word ‘sick’ in the show has prominent value on a deeper level, as stav has explained, but if we take it more surface level…

ALL i’m saying is that a ton of this stuff lines up. i don’t have a clear answer as to what exactly it means or how we got from A to B for sure, but it seems a lot like this richard character was interested in henry’s cancer-like regeneration abilities. possibly even in an attempt to prevent the process of aging. maybe, just maybe, richard brenner, richard henry creel, and martin brenner aren’t all that different *wink wink*

[lasseling]

FBI Records Reveal Fauci’s Agency Funded Gain-of-Function Research in Wuhan Lab That Would Leave No Trace of Human Manipulation

[anchesetuttinoino]

Incredibile: Fauci ha nascosto i piani per potenziare il virus del vaiolo delle scimmie, rendendolo molto più mortale

Secondo la Commissione energia e commercio della Camera dei rappresentanti USA Fauci aveva piani segreti per uno studio di guadagno funzionale del Vaiolo delle Scimmie, con il rischio di causare una vera epidemia ad alta mortalità.

Per quasi nove anni, l’Istituto di Anthony Fauci ha nascosto i piani per progettare un virus mpox, cioè il vaiolo delle scimmie, in grado di provocare una pandemia, con un tasso di mortalità fino al 15 percento, come hanno rivelato i membri di una commissione inquirente del Congresso degli Stati Uniti in un nuovo rapporto martedì 11 giugno.

Nel giugno 2015, uno scienziato del National Institute of Allergy and Infectious Diseases (NIAID) ha ricevuto l’approvazione formale da parte del National Institutes of Health’s Institutional Review Board per gli esperimenti che avrebbero dovuto progettare un virus mpox con alta trasmissibilità e moderata mortalità.

Ecco perchè i virologi marchettari continuano ad allarmare: "Vedrete il prossimo virus! Sarà una teraggeddia". Perchè LO SANNO che è in preparazione da anni.

L'articolo completo su Scenari Economici

[bpod-bpod]

Potential Pathogen

These yellow spheres are Staphylococcus aureus bacteria on the surface of a human immune cell (blue). They are found in, and on, about a third of the human population and are generally harmless except, that is, for when they’re not. S. aureus can cause severe and potentially fatal infections of the skin, soft tissues, bone and blood, and especially dangerous are the drug-resistant strains – so called, methicillin-resistant S. aureus (MRSA). The bacteria were thought to mainly inhabit the skin and nose, but recent research shows they are most abundant in the gut. This discovery led researchers to test whether probiotics – oral doses of friendly bacteria – could suppress S. aureus colonisation. And they could – by around ninety-five percent. Probiotics work more slowly than traditional antibiotics for tackling infections, but they can be taken for much longer without harm, and will likely be able to tackle MRSA strains when regular drugs cannot.

Written by Ruth Williams

Image from the NIH, National Institute of Allergy and Infectious Diseases (NIAID), Bethesda MD, USA

Research by Pipat Piewngam & Sunisa Khongthong, et al, NIAID and Rajamangala University of Technology Srivijaya, Thailand

Image in the Public Domain

Research published in Lancet Microbe, January 2023

You can also follow BPoD on Instagram, Twitter and Facebook

[youthkenworld]

Judicial Watch announced recently it received 5 pages of records from the Federal Bureau of Investigation (FBI) in a Freedom of Information Act (FOIA) request that show an April 2020 email exchange with several officials in the bureau’s Newark Field Office referring to Dr. Anthony Fauci’s National Institute of Allergies and Infectious Diseases (NIAID) grant to the Wuhan Institute of Virology (WIV) in China as including “gain-of-function research” which “would leave no signature of purposeful human manipulation.”

[lemondeabicyclette]

Dr. McCullough nomme les quatre principales personnes coupables de crimes contre l'humanité

1.) Dr. Anthony Fauci, Former Director of the National Institute of Allergy and Infectious Diseases (NIAID).

2.) Dr. Ralph Baric, Prof à la University of North Carolina at Chapel Hill

3.) Peter Daszak, President du EcoHealth Alliance.

4.) Dr. Shi Zhengli, virologue en chef du Wuhan Institute of Virology de Wuhan, Chine.

Autres nouvelles sur @Vigilant_News:

Suivez @VigilantFox 🦊

[adnan07]

The interferon response is one of the major innate immunity defences against virus invasion. Interferons induce the expression of diverse interferon-stimulated genes, which can interfere with every step of virus replication. Previous studies identified type I interfer- ons as a promising therapeutic candidate for SARS. In vitro data showed SARS-CoV-2 is even more senSitive to type I interferons than SARS-CoV, suggesting the potential effectiveness of type I interferons in the early treatment of COVID-19 (REF15). In China, vapor inhalation of interferon-a is included in the COVID-19 treatment guideline!5. Clinical trials are ongoing across the world to evaluate the efficacy of different therapies involving interferons, either alone or in combination with other agents52. Immunoglobulin therapy. Convalescent plasma treat- ment is another potential adjunctive therapy for COVID-19. Preliminary findings have suggested improved clinical status after the treatmentl55.1s, The FDA has provided guidance for the use of COVID-19 convalescent plasma under an emergency investigational new drugapplication. However, this treatment may have adverse effects by causing antibody-mediated enhance- ment of infection, transfusion-associated acute lung injury and allergic transfusion reactions. Monoclonal antibody therapy is an effective immuno- therapy for the treatment of some viral infections in select patients. Recent studies reported specific mon- oclonal antibodies neutralizing SARS-CoV-2 infection Inhibition of virus replication. Replication inhibitors include remdesivir (GS-5734), favilavir (T-705), ribavirin, lopinavir and ritonavir. Except for lopinavir and ritonavir, which inhibit 3Clpro, the other three all target RdRp28135 (FIG. 5). Remdesivir has shown activity against SARS-CoV-2 in vitro and in vivo28.136. A clinical study revealed a lower need for oxygen support in patients with COVID-19 (REF 137). Preliminary results of the Adaptive COVID-19 Treatment Trial (ACTT) clinical trial by the National Institute of Allergy and Infectious Diseases (NIAID) reported that remdesivir can shorten the recovery time in hospitalized adults with COVID-19 by a couple days compared with placebo, but the differ- ence in mortality was not statistically significant38, The FDA has issued an emergency use authorization for rem- desivir for the treatment of hospitalized patients with severe COVID-19. It is also the first approved option by the European Union for treatment of adults and adoles- cents with pneumonia requiring supplemental oxygen. Several international phase III clinical trials are contin- uing to evaluate the safety and efficacy of remdesivir for The treatment of COVID-19. Favilavir (T-705), which is an antiviral drug devel- oped in Japan to treat influenza, has been approved in China, Russia and India for the treatment of COVID-19. A clinical study in China showed that favilavir signif- icantly reduced the signs of improved disease signs on chest imaging and shortened the time to viral learancel, A preliminary report in Japan showed rates of clinical improvement of 73.8% and 87.8%

[darkmaga-retard]

Robert F. Kennedy, Jr. on his podcast recently interviewed Senator Rand Paul, one of the few members of Congress possessing moral values and intellectual integrity, about his confrontations with Dr. Anthony Fauci on the question of the origin of SARS-CoV-2, the coronavirus that causes COVID-19.

They discussed how the evidence indicates that the virus originated in the lab, and how Fauci’s agency, the National Institute of Allergy and Infectious Disease (NIAID) under the National Institutes of Health (NIH), funded risky “gain of function” research conducted by scientists at the Wuhan Institute of Virology in Wuhan, China, where the COVID-19 outbreak first occurred.

[jobrxiv]

Intramural NIAID Research Opportunities (INRO) 2025 Postbac Fellowship National Institutes of Health, National Institute of Allergy and Infectious Diseases Seeking recent grads for Intramural NIAID Research Opportunities, a unique paid postbac fellowship in #allergic, #immunologic, and #InfectiousDiseases See the full job description on jobRxiv: https://jobrxiv.org/job/national-institutes-of-health-national-institute-of-allergy-and-infectious-diseases-27778-intramural-niaid-research-opportunities-inro-postbac-fellowship/?feed_id=82379 #allergies #biology #biomedical_sciences #immunology #infectious_diseases #ScienceJobs #hiring #research