#arvc

[kiyomitakada]

what do you think misa would do with the death note if rem had brought it to her before light got his? or if light never got his?

oh my god hi thank you so much for the ask!!!!

so. hmm. misa immediately uses it to kill her parents' murderer, definitely — it's canon that she wanted to kill him even before kira appeared. since rem is the one who gives her the death note, she wouldn't go through the "is this a prank" phase light does. [not supported by canon but: i like to think she'd make his death hurt.] she also takes the shinigami eye deal, since she did in canon for non-light-related reasons (in case she ever runs into a stalker again, i'm guessing).

preface that this ^ is the only part that i'm sure of, everything else is entirely speculation that i could be convinced out of. but here's what i'm thinking so far:

it's tempting to say she'd kill people who wronged her/who she was jealous of as well, petty murders, but i don't think so. she knows kiyomi's and yuri's and mayu's names by the time she regains her memories but never actually writes them down (and we know she's good at cyberstalking so it's not a matter of whether she knows their faces or not)…

so instead i think she mostly goes after stalkers and similar forced-entry home-invasion murderers because she's never gotten over her parents, ever. (i deliberated for a bit over if she'd even want to use it, since misa doesn't care much about justice as a concept, but i really do think power like that is addictive.) misa doesn't particularly want to be god, and she doesn't really believe in establishing peace through fear as much as just killing all her enemies [live fast! die young! slay all my enemies!], so she mixes up the methods of death*. why would she want to be caught? the world probably doesn't even notice kira is a thing now, since misa is mostly focusing on japan. maybe a few reports about dropping crime rate but that's all.

[*honestly i have not convinced myself yet on this point. is misa lonely enough that she'd want her murders to be noticed? would she become kira just to have an adoring fanbase? we know she agrees with light's agenda, but would she have the motivation to start it on her own?

i debated myself on this for ages, but eventually decided that if you want to read that version of reality you should just read this fic instead because it's gorgeous and incredibly underrated and answers this question exactly. also it has kiyomi and mikami and naomi in it. but let's go in a different direction here.]

even better: gelus's death note isn't labeled DEATH NOTE, it's labeled ARVC-5 (fun fact, that's an irl gene that can cause sudden heart attacks!), so it's not suspicious and besides misa's already goth so she doesn't even bother hiding it much.

then either one of two things happens:

A) light comes into the picture

misa is kind of fucking annoyed now. in canon she's grateful to light for killing her parents' murderer of course, but in this universe that doesn't happen, so: this guy is making everything?? so obvious?? he killed someone on live television????

misa quickly realizes that the second kira is trying to establish a greater sort of justice, though, so she calms down. sure, why not, that's a nice goal. this is a much more selfless person than her, that's for sure.

the problem is that her group of people to murder overlaps strongly with light's. misa realizes this immediately, as in canon (where she murdered two celebrities to prove she was the second kira, picking victims she knew light wouldn't so the deaths wouldn't collide). if she keeps killing without coordinating with the new guy, he'll find out she exists, and she'd rather that happen on her terms and not his. she debates just sitting back and letting him handle things, but… no, what if he messes up? what if he's not as thorough as her? and besides, this is the only man on earth who could possibly understand what she's going through!

("i'm here too, you know," rem says.

"you don't count," misa dismisses. "you're not, like, human or anything.")

so she puts her plan in motion. i think she does this pretty much the same way, except that when the task force & co. respond to her tape (with light writing the whole "i'm the real kira and i don't think you should be threatening actual police officers" thing) misa isn't desperate enough to just concede. is this guy stupid or something? they need to kill L! (well, L's been kinda useless so far, but isn't it about the principle of the thing? didn't he kill lind l tailor??) so she sends the tape thanking kira for the response, but keeps insisting on showing L on live television. since kira is obviously incompetent, she also sends him the diary page right then and there.

this sends the task force into a bit of a panic. if L goes onto tv it's game over so they have to catch the "new" kira before then. and they've only got four days!

their only lead to the identity of the new kira is the fingerprints left on the tape envelopes. aizawa is ordered to look up the fingerprints in the npa database but doesn't find anyone (because misa's friend hasn't been arrested for any crimes and so her fingerprints aren't in there). light is fucking delighted. whoever this man is, he's smart! he didn't fall for L's tricks!

aaaand okay i was going to figure out the whole plot but i genuinely have no idea how L & co are getting out of that one so i'm stopping here. in broader terms: misa finds light regardless and they team up. misa still asks to be his girlfriend and still threatens to kill any girl who light talks to but doesn't give him her death note, which surely will not backfire. in general terms i think they start out on much more equal terms because misa doesn't see him as her savior but does still say she fell in love with him at first sight. iiii don't know if they devolve into canon dynamic over time or not, someone who understands yagamane better can handle that lmao (please feel free to add on to this post!!)

B) light never shows up

honestly? i think this is the worse end. misa's motive is less prevention and more punishment imo (not that we really get much of her motive in the first place), so she never really runs out of stalkers or burglars to kill. she becomes a model, and then an actor, still. sayu likes her movies and light only knows her name in reference to his sister's infodumps. maybe she marries someone; she tries to put it off because she's searching for that one true love, her soulmate, the other end of her red string, but she never finds him and she's turning thirty soon and if she doesn't marry soon her beauty will run out and no one will want her so she traps herself into marrying someone who is desperately in love with her (and reminds her of rem) (rem has no comment on this). if he ever tries to assault her, she reasons, she can just straight up kill him. he doesn't. but she never does love him, either.

and so misa amane dies alone. as she always does.

[stevencmendoza]

In a significant ruling, the US Bankruptcy Court allowed ASTRALABS to sell its investment warrant portfolio freely, releasing it from legal encumbrances. CEO Andrew Ryan hailed it as a victory, aiming for substantial returns. Investors praised Ryan's leadership. Moving forward, the focus will be on groundbreaking technologies at ARVC

[mcatmemoranda]

My attending was telling me about a pt he has who is a good student and athlete who gets chest pain when he does exercise. He started having syncopal episodes. So he went to peds cardiology, who did an EKG and said it was fine and he would grow out of it. He went to neurology and had MRI and MRA and was told it's nothing neurological. They went to Boston Children's Hospital, who said there was an epsilon wave on his EKG, so they did cardiac MRI and his right heart is larger than the left. The diagnosis hasn't been made yet, but essentially, he can't play sports or exercise anymore and the right side of his heart is going to keep enlarging until he dies from cardiac arrest. So he needs a heart transplant. So sad!

I don't know what an epsilon wave is. So I looked it up.

The epsilon wave is a specific ECG finding for arrhythmogenic right ventricular cardiomyopathy (ARVC), which is the second most common cause of unexpected sudden cardiac death in young people after hypertrophic obstructive cardiomyopathy.

[twinkl22004]

“Arrhythmogenic Right-Ventricular Dysplasia”, Victor McKusick, Mendelian Inheritance in Man, 1966. 心律失常性右心室发育不良 (ARVD5).

Here I present: “Arrhythmogenic Right-Ventricular Dysplasia”, Victor McKusick, Mendelian Inheritance in Man’, 1966. 心律失常性右心室发育不良 。(ARVD5). INTRODUCTION. Autosomal-dominant arrhythmogenic right-ventricular cardiomyopathy/dysplasia (ARVC/D) causes sudden cardiac death and is characterized by clinical and genetic heterogeneity. There is evidence that arrhythmogenic right-ventricular dysplasia type-5…

[petfurri]

Sotalol for Dogs: A Closer Look at its Effectiveness

Heart disease in dogs, particularly arrhythmias, can be a daunting challenge for pet owners and veterinarians alike. Sotalol, a beta-blocker with anti-arrhythmic properties, has become a key medication in the treatment of canine heart conditions, especially for controlling irregular heart rhythms. But how effective is Sotalol for dogs? This article takes a closer look at how Sotalol works, its benefits, and its overall effectiveness in managing canine heart disease.

How Sotalol Works

Sotalol is a unique medication because it acts as both a beta-blocker and a class III anti-arrhythmic drug. These dual actions target two major components of heart function:

Beta-blocking action: It slows down the heart rate by blocking the effects of adrenaline, which reduces the heart’s workload.

Anti-arrhythmic action: Sotalol blocks potassium channels in the heart, which helps prevent erratic electrical activity that can lead to irregular heartbeats.

This combination makes Sotalol particularly useful in treating:

Ventricular arrhythmias: Dangerous irregular heartbeats that originate in the lower chambers of the heart.

Atrial fibrillation: An irregular and often rapid heart rate that leads to poor blood flow.

Supraventricular tachycardia: A rapid heartbeat originating from the upper heart chambers.

Conditions Treated by Sotalol

Sotalol is often used in dogs with heart conditions such as ventricular tachycardia and supraventricular tachycardia, which are characterized by rapid or irregular heartbeats. These arrhythmias can cause the heart to pump less efficiently, reducing blood flow and potentially leading to serious complications such as fainting, lethargy, and even sudden cardiac death.

Breeds like Doberman Pinschers, Boxers, and other large dogs are often at a higher risk of heart arrhythmias, making Sotalol a life-saving medication for these pets.

How Effective is Sotalol?

Controlling Arrhythmias Sotalol is highly effective at managing ventricular arrhythmias, especially those that are life-threatening. Its ability to block potassium channels helps prevent the erratic electrical signals that cause rapid and irregular heartbeats, while the beta-blocking component slows the heart rate, allowing it to pump more effectively.For dogs with conditions like ventricular tachycardia, Sotalol helps stabilize the heart’s rhythm, reducing the risk of dangerous episodes. Studies and clinical experience show that Sotalol is particularly effective in controlling ventricular arrhythmias, which are the most concerning form of irregular heartbeats in dogs.

Reducing Symptoms and Improving Quality of Life Dogs with heart arrhythmias often experience symptoms like fainting (syncope), lethargy, and weakness. These symptoms occur because the heart isn’t able to pump blood effectively due to its erratic rhythm. Sotalol’s ability to stabilize the heart rhythm can significantly reduce these symptoms, leading to a noticeable improvement in the dog’s quality of life.Owners of dogs on Sotalol frequently report that their pets become more active and energetic after starting the medication. This is because the heart is functioning more efficiently, allowing the dog to engage in normal activities without experiencing weakness or fainting spells.

Prevention of Sudden Cardiac Death One of the most important benefits of Sotalol is its role in preventing sudden cardiac death in dogs with severe arrhythmias. Dogs with conditions like arrhythmogenic right ventricular cardiomyopathy (ARVC), particularly common in Boxers, are at high risk for sudden cardiac events. By controlling dangerous arrhythmias, Sotalol significantly reduces this risk, potentially saving the lives of at-risk dogs.

Benefits of Sotalol

Dual Action for Comprehensive Heart Care Sotalol’s effectiveness comes from its dual action as both a beta-blocker and an anti-arrhythmic agent. By targeting both the heart’s electrical signals and its response to adrenaline, Sotalol offers comprehensive control over heart rhythm issues. This makes it more effective than medications that only target one aspect of heart function.

Well-Tolerated in Most Dogs One of the reasons Sotalol is widely prescribed is because it is generally well-tolerated by dogs. While side effects can occur, most dogs experience only mild symptoms, such as fatigue, gastrointestinal upset, or low blood pressure, which typically resolve as the dog adjusts to the medication. This makes it a safer long-term option for managing chronic heart conditions.

Improves Long-Term Prognosis For dogs with chronic arrhythmias, Sotalol can improve their long-term prognosis by preventing worsening symptoms and reducing the likelihood of sudden cardiac events. Dogs that respond well to Sotalol often live longer, healthier lives, with fewer interruptions caused by fainting or fatigue.

How is Sotalol Administered?

Sotalol is given in tablet form and is usually administered twice daily. The dosage is determined based on your dog’s weight, heart condition, and overall health. Your veterinarian may start with a lower dose to gauge how well your dog tolerates the medication before increasing it to the optimal level.

Regular monitoring is essential, especially when starting Sotalol. Your veterinarian will likely use electrocardiograms (ECGs) and other tests to ensure the medication is effectively controlling your dog’s heart rhythm and that no adverse side effects are occurring.

Monitoring and Adjustments

Ongoing monitoring is a critical component of treatment with Sotalol. ECGs, blood pressure checks, and in some cases, Holter monitoring (a 24-hour heart monitor) are used to evaluate how well the medication is working. If the heart rhythm is still unstable or side effects become noticeable, the dosage may need to be adjusted.

For most dogs, Sotalol provides long-term benefits when regularly monitored, allowing veterinarians to make fine-tuned adjustments as needed.

Side Effects and Risks

While Sotalol is generally safe, some dogs may experience side effects. Common side effects include:

Fatigue or lethargy: This is due to the beta-blocking effect, which reduces the heart rate.

Gastrointestinal issues: Vomiting, diarrhea, or loss of appetite can occur, particularly in the early stages of treatment.

Low blood pressure: In rare cases, Sotalol can cause hypotension, leading to fainting or weakness.

Most side effects are manageable and improve over time. However, if you notice any severe reactions, it’s essential to contact your veterinarian immediately.

When is Sotalol Not Recommended?

Sotalol is not suitable for all dogs. It should be avoided or used cautiously in dogs with certain conditions, such as:

Bradycardia: Dogs with a naturally slow heart rate may experience worsening symptoms if placed on Sotalol.

Congestive heart failure: In some cases, Sotalol may not be the best choice for dogs with severe heart failure.

Kidney disease: Since Sotalol is excreted through the kidneys, dogs with kidney disease may not be ideal candidates for this medication.

Your veterinarian will thoroughly assess your dog’s health before prescribing Sotalol to ensure it’s the right option.

Conclusion

Sotalol has proven to be an effective and reliable medication for dogs suffering from heart arrhythmias. By controlling irregular heartbeats, reducing symptoms like fainting and lethargy, and preventing sudden cardiac death, Sotalol plays a critical role in managing canine heart disease. Its dual action as both a beta-blocker and anti-arrhythmic agent offers comprehensive heart care, making it a hidden gem for many dogs with life-threatening arrhythmias.

If your dog has been diagnosed with a heart condition, consult with your veterinarian to determine if Sotalol is the right treatment. With regular monitoring and proper administration, Sotalol can help your dog live a healthier, more active life despite heart disease.

[heartheathblogs]

Understanding Epsilon Wave ECG: A Crucial Indicator in Cardiology

Epsilon waves on an electrocardiogram (ECG) are a critical diagnostic marker in cardiology, especially for identifying arrhythmogenic right ventricular cardiomyopathy (ARVC). These small, positive deflections occurring at the end of the QRS complex are prominently observed in the right precordial leads (V1-V3). They are indicative of ARVC, a condition characterized by the replacement of normal myocardial tissue with fibrofatty tissue in the right ventricle, leading to delayed depolarization.

Recognizing epsilon waves is essential because ARVC can cause serious cardiac arrhythmias and sudden cardiac death, particularly in younger individuals and athletes. Early identification of these waves allows for prompt intervention, which may include lifestyle changes, medications, or the implantation of cardioverter-defibrillators (ICDs) to manage and prevent potentially life-threatening arrhythmias.

Therefore, understanding and identifying epsilon waves are crucial skills for cardiologists and healthcare providers. Their presence can significantly impact diagnostic accuracy and treatment strategies, ultimately enhancing patient care and reducing the risk of sudden cardiac events. Proper recognition and management of epsilon waves play a key role in the effective treatment of ARVC and improving patient outcomes.

[k12academics]

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You can help twice as much because we match every donation made to One Tree Planted on our website.

And your support also helps us provide recycling education to schools and day camps, support national and local recycling initiatives, donations to aid multiple underserved schools, medical and hospice facilities, and the ARVC to name a few.

You are doing more good than you know when you partner with Polly Products.

[jayeshsaini006]

ARRHYTHMOGENIC RIGHT VENTRICULAR CARDIOMYOPATHY: INSIGHTS INTO PATHOGENESIS AND MANAGEMENT

[healthkenya7]

ARRHYTHMOGENIC RIGHT VENTRICULAR CARDIOMYOPATHY: INSIGHTS INTO PATHOGENESIS AND MANAGEMENT

Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC), also known as Arrhythmogenic Right Ventricular Dysplasia (ARVD), is a rare genetic heart disorder characterized by progressive replacement of normal heart muscle tissue with fibrous and fatty tissue, particularly in the right ventricle (RV) of the heart. This pathological remodeling of the heart can lead to arrhythmias, heart failure, and sudden cardiac death, especially in young individuals and athletes. ARVC primarily affects the right ventricle but can also involve the left ventricle.

Pathogenesis: The exact cause of ARVC is complex and involves genetic, molecular, and cellular factors. It's generally considered to be a disease of desmosomes, which are specialized structures that connect adjacent heart muscle cells (cardiomyocytes) and play a critical role in maintaining the structural integrity of the heart. Mutations in genes that encode desmosomal proteins have been identified as a major contributor to the development of ARVC. These mutations can lead to disruptions in cell-to-cell adhesion and communication, ultimately causing the fibrofatty replacement of myocardial tissue.

The pathological process involves several steps:

Genetic Predisposition: ARVC is typically inherited in an autosomal dominant manner, which means that a person has a 50% chance of inheriting the mutated gene from an affected parent. Mutations have been identified in several genes, including PKP2, DSP, DSG2, DSC2, and others, which code for proteins involved in cell adhesion and intercellular communication.

Myocyte Injury and Replacement: Genetic mutations disrupt the function of desmosomes, leading to cellular damage in response to mechanical and electrical stress. As a result, injured myocytes are replaced by fibrous and fatty tissue, causing progressive myocardial thinning and dilation.

Arrhythmogenesis: The structural changes in the heart disrupt the normal propagation of electrical signals, leading to arrhythmias. The fibrous tissue acts as an insulator, creating areas of slowed conduction and facilitating reentrant circuits that can trigger ventricular arrhythmias, including ventricular tachycardia and fibrillation.

Clinical Presentation: ARVC's clinical manifestations can vary widely, ranging from asymptomatic cases to life-threatening arrhythmias. Common symptoms and findings include:

Palpitations

Syncope (fainting)

Ventricular arrhythmias

Right-sided heart failure symptoms (due to RV dysfunction)

EKG abnormalities (ST-segment elevation in precordial leads, T-wave inversion)

Echocardiographic and cardiac MRI findings (RV enlargement, regional wall motion abnormalities, fatty infiltration)

Diagnosis: The diagnosis of ARVC involves a combination of clinical, genetic, electrocardiographic, imaging, and histopathologic criteria. It's important to consider family history, genetic testing, imaging studies (echocardiography, cardiac MRI), and electrophysiological studies (including Holter monitoring and exercise stress testing).

Management: The management of ARVC is multifaceted and aims to prevent arrhythmias, manage heart failure symptoms, and reduce the risk of sudden cardiac death. Treatment strategies include:

Medications: Antiarrhythmic drugs may be prescribed to manage arrhythmias, while heart failure medications can help improve RV function.

Implantable Cardioverter-Defibrillator (ICD): People at high risk of life-threatening arrhythmias may receive an ICD to monitor and treat abnormal heart rhythms by delivering an electrical shock when necessary.

Catheter Ablation: Radiofrequency ablation can be used to target and eliminate the sources of arrhythmias in the heart.

Lifestyle Modifications: Physical activity restriction is often recommended, especially for those with a history of arrhythmias.

Genetic Counseling: Since ARVC is genetic, genetic counseling and testing are crucial for affected individuals and their families to understand the inheritance pattern and potential risks.

Regular Follow-Up: Regular cardiac evaluations are essential to monitor disease progression and adjust treatment strategies as needed.

Mr. Jayesh Saini says, “ARVC is a complex genetic heart disorder characterized by fibrofatty replacement of myocardial tissue, leading to arrhythmias and heart failure. Its diagnosis and management require a multidisciplinary approach involving clinical, genetic, imaging, and electrophysiological assessments. Early identification and appropriate treatment are essential to improve outcomes and reduce the risk of sudden cardiac death.”

#jayeshsaini #kenya #healthcare #LifeCareHospitals #Kenya #NHIF #NPS #TSC#healthy

[drramjimehrotra]

(Dr Ramji Mehrotra) What are Inherited Cardiac Conditions?

Inherited cardiac conditions are a group of cardiovascular disorders that are caused by genetic mutations or abnormalities passed down from parents to their children. These conditions can affect the structure or function of the heart and may occur at various stages of life, from infancy to adulthood. Understanding the nature of inherited cardiac conditions is crucial for early detection, proper management, and preventive measures.

One prominent example of an inherited cardiac condition is hypertrophic cardiomyopathy (HCM). HCM is characterized by the thickening of the heart muscle, particularly in the left ventricle. This abnormal thickening can disrupt the heart's pumping ability and lead to symptoms such as chest pain, shortness of breath, and palpitations. In some cases, HCM can cause sudden cardiac arrest, especially during intense physical activity.

According to Dr. Ramji Mehrotra, leading cardiac surgeon in NCR region, genetic mutations in genes responsible for the structure of cardiac muscle proteins are often associated with HCM. Diagnosis typically involves a combination of clinical evaluation, imaging tests like echocardiography, and genetic testing to identify specific mutations. Management may include medications to alleviate symptoms, lifestyle modifications, and, in severe cases, surgical interventions.

Another inherited cardiac condition is Long QT syndrome (LQTS), which affects the electrical system of the heart. Individuals with LQTS have an abnormality in the ion channels responsible for regulating the heart's electrical activity. This can lead to irregular and potentially life-threatening arrhythmias, including a specific type known as Torsades de Pointes.

Symptoms of LQTS may include fainting, seizures, and sudden cardiac arrest. Genetic testing can identify mutations associated with LQTS, and electrocardiograms (ECGs) are used to evaluate the heart's electrical activity. Treatment typically involves medications to prevent arrhythmias, lifestyle modifications, and the avoidance of certain medications that can prolong the QT interval.

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited cardiac condition that affects the structure and function of the heart's right ventricle. In ARVC, the normal muscle tissue in the right ventricle is progressively replaced by fatty or fibrous tissue, leading to abnormal heart rhythms and, in some cases, heart failure. Genetic mutations involving proteins responsible for maintaining the structural integrity of heart cells are often associated with ARVC. Diagnosis may involve a combination of clinical evaluation, imaging tests like cardiac MRI, and genetic testing. Treatment typically focuses on managing arrhythmias, preventing sudden cardiac death, and addressing heart failure symptoms through medications, implantable devices like defibrillators, and lifestyle modifications.

Marfan syndrome is an inherited connective tissue disorder that can also affect the cardiovascular system. It is caused by mutations in the FBN1 gene, which leads to abnormalities in the production of the protein fibrillin-1. Fibrillin-1 is a crucial component of connective tissue that provides strength and elasticity to various structures, including the heart's valves and aorta.

In individuals with Marfan syndrome, the aorta can be weakened and dilated, increasing the risk of aortic dissection or rupture. Diagnosis involves clinical evaluation, imaging tests like echocardiography, and genetic testing to confirm the presence of FBN1 mutations. Treatment may include medications to manage symptoms, regular monitoring of the aorta's size, and surgical interventions to repair or replace the affected valves or aorta if necessary.

Dr. Ramji Mehrotra says that understanding the genetic basis of inherited cardiac conditions, along with appropriate diagnostic strategies and management approaches, is crucial for early detection, prevention of complications, and optimal care.

[beastlyautoimmunity]

I swatched some red paint to decide on a colour theme for a doll, the swatches are hearts to make it fancy. ‘Oats help to lower LDL cholesterol’ #beastlyautoimmunity #floridfebruary #hearts #heartdiseaseawareness #arvc #arvd #cholesterol #heartswatches #february #february2019 #2019 https://www.instagram.com/beastlyautoimmunity/p/BudHVV7DhPZ/?utm_source=ig_tumblr_share&igshid=1ucj16blig778

[raceacrossamerica]

A well deserved article in today’s paper, in the sports section in great company. Bravo @may_philippe and @gianniveganultra #winforce #we_are_sungod #infinityseat #raam #raceacrossamerica #raam2man #cyclinglife #livetorideridetolive #livingwitharvd #arvd #arvc #ilovetoridemybicycle https://www.instagram.com/p/CQ8xz2JL0P1/?utm_medium=tumblr

[theheartgene]

This is where the journey begins. I’m making my story public in hopes others may need it.

[bulltruearchive]

can’t  believe  lestat  was  just  like  nicki  is  the  love  of  my  life  &  ill  love  him  forever  but  then  he  saw  louis  &  was  like  lmao  nicki  who

[mikami]

what are the weirdest/craziest/ most unknown deathnote facts you know?

It actually feels like there isn’t a whole lot of crazy Death Note knowledge because the whole production history is kept pretty much on the down low and we don’t know a lot beyond what is in the manga...

Best I can think of is these..

It’s a mystery why the Red Hot Chili Peppers did the theme song for the Live Action movie. The staff didn’t even know who they were.

Mello’s gun is from the movie Romeo+Juliet.

Yamamoto and Yamamoto might not be the same person...?

Light’s chip preferences were localized for the VIZ English translation of the manga. His favorite flavor is actually Consommé and not Barbeque.

The writing on Rem’s notebook is in some shinigami letters but it could read as ARVC-5, which is an illness that can cause cardiac arrest.

According to an interview published on the DVD version of Death Note, Mamoru Miyano got so into playing Light that he started feeling depressed in daily life during his time working on the show, which is normally very unlike him.

Literally everything that happens in the German Audio Drama is so bonkers that I can’t pick a favourite.

L’s character design was inspired by Devilman, of all things.

But mostly I know a lot of pretty unknown but also really boring information á la “the university tennis club captain is named Yasunaga in the Japanese manga but his name was omitted from the VIZ translation”...

[deathnotefacts]

The writing on the front of Gelus's death note is in shinigami letters, but it could also be read as ARVC-5; a gene which can cause sudden heart attacks.

(fact by @mikami)