#cardiomyopathy

[imperatordavianus-blog]

Hmm, strange that I couldn't edit. But here's more female enlarged hearts and aneurysms. I remembered that Cassandra-Heart Queen informed me that not only she had an enlarged heart but also a thoracic aortic aneurysm. Dunno if she has told anyone else about it.

[bpod-bpod]

Mutant Muscle Model

The X-linked inherited genetic disorder Becker muscular dystrophy has an onset at around 30 years-of-age and with the first sign being heart failure in many. A new rat model of the disorder faithfully mimics human abnormalities, and demonstrates progressive cardiomyopathy enabling aspects of early disease to be examined

Read the published research article here

Image from work by Valentina Taglietti and colleagues

Univ Paris-Est Créteil, INSERMU955 IMRB F-94010 Créteil France

Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)

Published in EMBO Reports, October 2024

You can also follow BPoD on Instagram, Twitter and Facebook

[last-tambourine]

On Christmas Eve, a man resurfaces, placing a bouquet of purple foxgloves on her bed. She has known him since childhood: they grew up together—lovers, friends, brother and sister, partners in crime. They are, for each other, almost everything a man and a woman can be.

[...]

Actually, he tells her, the digitalin contained in the flowers makes the heartbeat stronger, slower, steadier. It’s good for you.

She sleeps with the flowers that night. The man carefully undresses her, removing the petals one by one, then placing them on her naked skin like the scales of a fish, a sort of organic jigsaw puzzle that he painstakingly perfects into a ceremonial gown, whispering don’t move from time to time, even though she has long been asleep, in a luxuriant catalepsy, nursed and ornamented like a queen. It was still night when she awoke, but the children in the apartment above hers were already running around excitedly, shouting, their footsteps hammering the floorboards, rushing into the living room to tear the wrapping paper from the presents that had appeared during the night around the ectoplasmic Christmas tree. Her friend had gone. She shook the petals from her body and made them into a salad that she seasoned with truffle oil and balsamic vinegar.

~ The Heart, Maylis de Kerangal, Sam Taylor (Translation)

[healthbeauty204]

Cardiomyopathy symptoms: Weak Heart Explained https://healthsnbeauty.com/cardiomyopathy-symptoms-weak-heart-explained/?utm_source=tumblr&utm_medium=social&utm_campaign=Health+%26+Beauty+tips

[myrawjcsmicasereports]

 Epsilon Wave in Arrhythmogenic Cardiomyopathy by Luis López-Flores in Journal of Clinical Case Reports Medical Images and Health Sciences

Clinical Image

A 54-year-old woman with hypertension presented to the emergency department after syncope occurred during prolonged standing. On arrival, heart rate and blood pressure were normal. Admission electrocardiogram (Figure 1, A) showed sinus rhythm at 55 bpm, PR 200 ms, a wide QRS complex with morphology of complete right bundle branch block (width 180 ms), with small electrical potentials immediately after the QRS in all leads, more variegated in right precordial leads – findings suggestive of epsilon wave-, and a negative T wave in all precordial leads. A subsequent electrocardiogram (Figure 1, B) also revealed ventricular extrasystoles of two morphologies, with criteria of epicardial origin, and in which the low amplitude component at the end of the QRS was also appreciated. Echocardiography showed severe biventricular systolic dysfunction and right ventricular (RV) apical akinesia. Cardiac magnetic resonance imaging confirmed the findings and further revealed areas of RV dyskinesia and late gadolinium enhancement at the subepicardial level of both ventricles. Coronary angiography showed no coronary lesions. With the diagnosis of arrhythmogenic cardiomyopathy, an implantable cardioverter defibrillator was implanted for primary prevention.

Epsilon wave is a major criterion for the diagnosis of arrhythmogenic cardiomyopathy and reflects a delay in ventricular depolarization due to replacement of myocardial fibbers by fibroadipose tissue. The presence of epsilon waves beyond the right precordial leads is exceptional; however, in patients with left ventricular involvement, the epsilon wave may be recorded in the left and/or inferior leads, as illustrated in this case.

[groovy-hearted]

there is a special kind of grief reserved for slowly losing the ability to do everything you love because your body won’t let you anymore

[cardiologistdrfarhanshikoh]

कार्डियोमायोपैथी के कारणों को समझना

कार्डियोमायोपैथी एक ऐसी स्थिति है जो हृदय की मांसपेशियों को प्रभावित करती है, अगर समय रहते इसका समाधान न किया जाए तो यह गंभीर जटिलताओं का कारण बन सकती है। यहाँ कुछ सामान्य कारण दिए गए हैं:

दीर्घकालि�� उच्च रक्तचाप: लगातार उच्च रक्तचाप हृदय पर अत्यधिक दबाव डालता है, जिससे हृदय की मांसपेशी कमज़ोर या मोटी हो सकती है।

हार्ट अटैक से हृदय के ऊतकों को नुकसान: हार्ट अटैक हृदय के ऊतकों पर निशान छोड़ सकता है, जिससे रक्त को कुशलतापूर्वक पंप करने की इसकी क्षमता कम हो जाती है।

क्रोनिक रैपिड हार्ट रेट: लगातार तेज़ हृदय गति हृदय को अधिक काम दे सकती है, जिससे अंततः संरचनात्मक क्षति या कमज़ोरी हो सकती है।

हार्ट वाल्व की समस्याएँ: स्टेनोसिस या रेगुर्गिटेशन जैसी हृदय वाल्व की समस्याएँ, हृदय को रक्त पंप करने के लिए अधिक मेहनत करने के लिए मजबूर करती हैं, जिससे समय के साथ कार्डियोमायोपैथी हो सकती है।

मोटापा: अधिक वजन उठाने से उच्च रक्तचाप और मधुमेह जैसी स्थितियों का जोखिम बढ़ जाता है, जो हृदय पर दबाव डालती हैं।

थायरॉयड विकार: अति सक्रिय और कम सक्रिय थायरॉयड ग्रंथियाँ हृदय के कार्य को प्रभावित कर सकती हैं, जिससे संभावित रूप से कार्डियोमायोपैथी हो सकती है।

परामर्श के लिए, Dr. Md. Farhan Shikoh, MBBS, MD (Medicine), DM (Cardiology से सुकून हार्ट केयर, सैनिक मार्केट, मेन रोड, रांची, झारखंड: 834001 पर संपर्क करें। 📞 फ़ोन: 6200784486 🌐 वेबसाइट: https://drfarhancardiologist.com/

जानकारी रखें और अपने हृदय स्वास्थ्य को प्राथमिकता दें।

[savagecuhnt]

oh, don't be cute.

*lays her head in his lap, kicking her bare feet up on the arm of the couch* “you gonna try to stop me?” *presses the open bottle of wine to his lips* “shh… sip time.”

[anxious-ruins]

You were all love, nothing less. I'm struggling so hard with the loss of you. You loved me no matter what, I'll never stop missing you.

[imperatordavianus-blog]

For those who are wondering. Do giant hearts exist? And the answer is yes. And do women get them? Yes, yes they do. And can a woman have aneurysms of her great blood vessels? Yes, yes they can. And in fact, here are some perfectly great examples of the.

Cardiomegaly and Aneurysms of the great blood vessels.

https://www.researchgate.net/figure/Idiopathic-dilated-cardiomyopathy-in-a-28-year-old-woman-with-shortness-of-breath-a_fig2_221781930

https://www.researchgate.net/figure/Fig-1-Extremely-enlarged-heart-a-Chest-X-ray-film-shows-marked-cardiomegaly-b_fig1_46168679

https://www.researchgate.net/figure/Chest-X-Ray-shows-ascending-aortic-aneurysm-and-cardiomegaly_fig1_304779128

https://www.researchgate.net/figure/Chest-x-ray-for-patient-2-a-30-year-old-woman-showing-a-globular-heart-with-oligemic_fig2_233888689

https://www.researchgate.net/figure/Aortic-enlargement-of-sac-formation-in-a-patient-with-TBAD-A-A-60-year-old-woman-with_fig3_320966026

https://www.researchgate.net/figure/Dilated-cardiomyopathy-Echocardiographic-and-cardiac-magnetic-resonance-images-from-a_fig3_271533595

https://www.researchgate.net/figure/Imaging-exams-displaying-the-pulmonary-aneurysm-and-associated-features-A-Chest_fig1_51740514

https://www.researchgate.net/figure/Three-patterns-of-aortic-dilation-in-patient-with-BAV-A-Dilated-tubular-ascending_fig1_319422738

https://cardiothoracicsurgery.biomedcentral.com/articles/10.1186/s13019-021-01600-0

https://www.sciencedirect.com/science/article/pii/S1930043316303739

https://www.researchgate.net/figure/Illustrations-of-type-II-thoracoabdominal-aortic-aneurysm-repair-with-adjuncts-A_fig2_223526560

https://www.researchgate.net/figure/Preoperative-CT-scan-showing-a-type-III-thoracoabdominal-aortic-aneurysm-that_fig1_24440788/amp

https://www.researchgate.net/figure/The-photographs-showing-Large-Globular-shaped-heart-in-case-of-Dilated-Cardiomyopathy_fig1_354563009

https://www.wikidoc.org/index.php/Cardiomyopathy_pathophysiology

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142248/

https://pubmed.ncbi.nlm.nih.gov/3155900/

https://www.ajconline.org/article/S0002-9149(19)31189-0/fulltext

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805784/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574292/

https://www.heartlungcirc.org/article/S1443-9506%2823%2904225-7/fulltext

https://www.researchgate.net/figure/Reconstructed-CT-image-showing-a-hugely-dilated-left-atrium-extending-to-the-right-of_fig9_319309937

Peripartum cardiomyopathy

https://www.sciencedirect.com/science/article/pii/S2210261216303662

Now for a poll to all the big breasted women out there. Do you have these? And explain why?

[bpod-bpod]

Energy Production Failure

The heart on the left is healthy but the one on the right exhibits the tell-tale signs of dilated cardiomyopathy, including overall enlargement, and thinning and weakening of the muscle walls. In most cases of such cardiomyopathy, the cause is unknown, but recent research indicates dysfunctional energy production, already known to accompany the condition, may actually be an underlying cause. Analysis of gene activity in heart tissue from patients with dilated cardiomyopathy and healthy controls showed expression of mitochondrial metabolism genes, especially two key transcription factors – KDM8 and TBX15 – was disrupted in patient samples. When scientists then deleted KDM8 in mouse hearts, they found the knock-on disruption of TBX15 and other metabolism genes preceded physical signs of cardiomyopathy by months. Knowing that impaired energy production can initiate rather than simply follow myocardial degeneration suggests maintaining it may be a way to slow or stop heart failure.

Written by Ruth Williams

Image from work by Abdalla Ahmed and colleagues, Paul Delgado-Olguín lab

Department of Translational Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada

Image copyright held by the original authors

Research published in Nature Cardiovascular Research, February 2023

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[crimsonpublishersbiosciences]

A Case of Unrecognized Peripartum Cardiomyopathy Which Was Noticed During Emergency Cesarean Section_Crimson Publishers

Abstract:

Per partum cardiomyopathy (PPCMP) is a kind of dilated cardiomyopathy seen between the last week of gestation and the postpartum 5th month. PPCMP may be a cause of mortality for the mother and the infant. PPCMP is associated with black race, multi parity, maternal age above 30 years, multiple pregnancy, preeclampsia, eclampsia, family history, obesity, smoking, diabetes mellitus, and hypertension, but the underlying cause is not clear [1]. In this case report, we present the diagnosis of per partum cardiomyopathy, anesthetic management, and postoperative intensive care period in a patient who developed pulmonary edema during emergency cesarean operation. We aimed to underline that per partum cardiomyopathy should be remembered among the presumed diagnoses in case of acute pulmonary edema.

Read More About this Article: https://crimsonpublishers.com/sbb/fulltext/SBB.000535.php

Read More Articles: https://crimsonpublishers.com/sbb/index.php

[healthbeauty204]

Cardiomyopathy: Weakened Heart Muscle https://healthsnbeauty.com/cardiomyopathy-weakened-heart-muscle/?utm_source=tumblr&utm_medium=social&utm_campaign=Health+%26+Beauty+tips

[symbiosisonlinepublishing]

insulin is an effective #hyperglycemia agent, however hyperinsulinemia, as result of prolonged administration, has been shown to lead to #cardiovasculardisease (CVD) in DM. As a result, research into alternative therapies for the management of #diabetes is needed. In our laboratory, a novel vanadium complex has been synthesized and has been shown to improve #glycemic control and #liverfunction.

Visit @ https://symbiosisonlinepublishing.com/endocrinology-diabetes/endocrinology-diabetes154.php

[groovy-hearted]

I was lied to FOR YEARS about my heart by doctors and it had to take me weeks of studying cardiac mri imaging to realise how fucking bad it got