#animation schools in india

[bixels]

Reminiscing about Little Witch Academia.

[swan-diaries]

Moonlight prince 🌝 soma = moon

Rajkumar Soma

[kathybluecaller]

when I give up on fully drawing Strive so my boy despawns for a solid 6 frames

(don’t mind the animation rant in the tags that I may continue on a later date)

[cartoonnetworkchannel-india]

Ben 10 | Ben 10 Cartoons | Watch Ben 10 Superpowers | Only on Cartoon Network

Kya aap ko life mai action aur variety pasand hai? Tho humare alien hero ke sath hangout kijeye. Dekheye Ben 10 ko Hindi mai Cartoon Network India pe.

Do not miss any updates on your favorite #cartoons by Subscribing to the Cartoon Network India YouTube Channel, Facebook page & Instagram page

YouTube - https://www.youtube.com/@cnindia Facebook - https://www.facebook.com/CartoonNetwork.India Instagram - https://www.instagram.com/cartoonnetworkindia/

ben10 #ben10omniverse #omniverse #benten #superhero #cartoonnetwork #superpowers #kidscartoon #cartoonvideos #kidsvideo #kids #cartoonforkids #ben10alienforce #cartooncharacters

[deifiedsensei]

Welcome To Demon School Iruma Kun Season 1 Episode 7 In Hindi || Anime In Hindi ||

Welcome to Demon School! Iruma-kun is an anime series adapted from the manga series, written by Osamu Nishi. #DeifiedSensei   #anime  #iruma  #demon  #school   #season -1  #episode -7 #irumakun #WelcometoDemonSchoolIruma #animeinhindi #animeinhindiexplained

[thescrcservices]

Get best Ph.D. Services from expert writers .

Contact us: 6268991983

Mail us: scrcoffice@gmail.com

Visit: www.thescrc.org

[the-rsace]

RSACE is one of the best animation schools in India, offers best animation certificate courses Call or visit now at RSACE

[motherofplatypus]

Record of Genocide

[Part 2]

An opening:

The List:

Upon Children:

Beheading baby

Shot a kid that's running away

Shot a kid (again)

Shot a 6 years old 355 times

Slit a kid's throat

Creating a 14 pages long list of killed children under 1 year old

Bombed a pregnant lady that her fetus expelled from her

Burn a student alive

Torturing and sexually abusing civilians, including children

Blow a child's head until their brain splattered on the ground

Killing newborn twins, not even 4 days since their birth

Death toll from October 15th 2023 to July 6th 2024. 16k+ were children.

Released a dog to attack civilian (kid version)

44% of killed victims are children.

Killed a man's entire family, including his children

Harris' supporter harassing a baby

Killed a child when he was at the market with his mother

Killing an 8 years old girl along with 36 of her family members

US participation in genocide upon children

Assraeli soldier took a bike from a kid and throw it in the trash

Assrael killed a man's son (1)

Assrael killed a man's son (2)

Assrael killed a man's daughter

Assrael killed a man's daughter (2)

Assrael abused a 12 years old girl in prison, the youngest female to be held in prison

Assrael killed a mother's 3 daughters and her sister

Assraelis mocks children who lost their limbs and murdered

Assrael killed a mother's child

Upon Palestinian In General:

Killing Christians.

Demanding the rights to rape

Burning people alive

A concentration camp

Torturing civilians (featuring French people)

Destroying churches, hospitals, and schools

Bombing schools

Bombing civilians in their tents

Admitance of ethnic cleansing

Banning maternity kit and anaesthetic

Disguising as civilian to kill civilians

Destroying humanitarian aids

Released a dog to attack civilian

Bombing refugee camp

Stealing houses from their owner

Deliberately destroying properties in Lebanon (confirmed by UN peacekeepers)

Bombing school where people take shelter

Celebrating Trump's victory by shooting at homes in Gaza (featuring Trump's supporter)

Killing an entire family in a targeted attack

A Knesset member sending death threats in hospital

Using AI to kill more people

Publicly announcing annexation of Gaza

UNICEF spokesperson talked about the horror Assrael committed upon civilians

Targeting civilians in Safe Zone

Destroying humanitarian aids

Assraeli blowing up praying site

UK surgeon explains what Assrael did in Gaza

Assraeli glorifying the crimes their fallen soldiers committed

A son breakdowns during praying for his father that's killed by Assrael

A doctor's testimony of what Assrael did

The bodies of the people Assrael killed

Assrael bombing UN-run school, killing 10 people

Upon Lebanon:

Blows up an entire village in Lebanon

Assrael bombed Lebanon near a school

Assrael targeting civilians in Lebanon, killing at least one child

Assrael bombed a suburbs in Lebanon

Assraeli destroying an entire village in Lebanon

Assraeli killed 2 doctors and orphaned their child

Destroying praying site in Lebanon

15 paramedics in Lebanon murdered by Assrael

Upon Non-Palestinians:

Killing WCF workers (3 from UK, 1 from US, 1 from Australia, 1 from Poland, and 1 from Palestine.)

Attacking UN workers, killing 3 children during their attacks

Killing a medical worker through torture

Killing journalist (this is only two of 100+ journalists they've killed)

Beating and torturing journalist (featuring American journalist)

Attacking WFP workers

Bombing a UN shelter (featuring India)

Assaulting civilians in Athens

Ally in genocide (featuring USA)

An ambassador signing bombs before being dropped on civilians (featuring USA)

Killing animals

Ramming a police deliberately but no consequences (featuring USA)

META's complicity in genocide

Targeting family homes in Beirut

Assrael journalist demanding more violence, deaths, and river of blood

Bombed a residential building and killed 7 people in Syria

Harassment upon the people in Amsterdam

Property damage to assault people in Amsterdam

Assraeli physically attacked a woman

Biden's inappropriate answer to journalist who asked about the hostages

Assraeli hooligans singing song of death threats in Amsterdam

Assraeli hooligans attacking French people

Assrael genocide impact on animals

Justifying targeting civilians (featuring Germany)

Assraeli inciting violence on TV

The Pope calling Assrael as terrorist

AIPAC openly bragging about buying the US elections

Assraeli harassing a Christian tourist and defiling his cross necklace

Assraeli using genocide as tourist attraction

How US's "threat" on Assrael went

Where the US put their own people compared to Assrael

This is not a complete list.

[dandelionsresilience]

Dandelion News - February 1-7

(sorry it’s late, I’ve had pneumonia. between fever and meds, today was the first day in over a week I could even think)

Like these weekly compilations? Tip me at $kaybarr1735 or check out my Dandelion Doodles!

1. These solar streetlights can withstand Category 5 hurricanes

“[The solar-powered streetlights] can identify potential problems before an outage occurs, identify current outages without the need for customer reporting, and allow for remote control of brightness settings. The streetlights are built to remain operational even during widespread power outages.”

2. 15 Democratic state AGs stand by gender-affirming care

“"Federal funding to institutions that provide gender-affirming care continues to be available, irrespective of President Trump’s recent Executive Order," the attorneys general say. […] “Health care decisions should be made by patients, families, and doctors, not by a politician trying to use his power to restrict your freedoms.”

3. India doubles tiger population in a decade

“[India has protected] the big cats from poaching and habitat loss, ensuring they have enough prey, reducing human-wildlife conflict, and increasing living standards for communities near tiger areas.”

4. A North Carolina wildlife crossing will save people. Can it save the last wild red wolves too?

“There are thought to be fewer than 20 red wolves left in the wild[…. S]tate agencies and nonprofit groups [plan to] rebuild a 2.5-mile section of the highway with fencing and a series of culverts, or small underpasses, to allow red wolves – as well as black bears, white-tailed deer and other animals – to pass safely underneath traffic.”

5. Merrimack Valley public transit system will keep bus fares free

“[… C]ollecting fares [used to] cost MeVa about $300,000 a year to maintain fare boxes, pay staffers and afford insurance. Since going fare free in 2022, the report found ridership increased 60% from pre-pandemic levels[….] The program is now funded by state allocated funds, including money from the so called “millionaire’s tax.””

6. Health care is key for youths getting out of prison. A new law helps them get it

“[The new law] requires all states to provide medical and dental screenings to Medicaid- and CHIP-eligible youths 30 days before or immediately after they leave a correctional facility. Youths must continue to receive case management services for 30 days after their release.”

7. World’s smallest otter makes comeback in Nepal after 185 years

“Scientists have for the first time in 185 years confirmed the presence of the Asian small-clawed otter in Nepal[….] The last time the […] the smallest of the world’s 13 known otter species, was recorded by scientists in Nepal was in 1839.”

8. B.C.'s smallest First Nation has big plans for a 'stewardship' economy

“The Kwiakah Centre of Excellence will be the base for a dedicated research station, an experimental kelp farm, the nation’s regenerative forestry operations and its territorial Indigenous guardian, or Forest Keepers, program[…. R]esults will include a 100-year management plan that integrates climate, salmon, kelp, and soil research to protect territorial waters and remaining old growth forests.”

9. Glades County schools deploy 13 new Blue Bird electric school buses

“The students at the Glades County school district will directly benefit from the cleaner, quieter rides, and operational cost savings that electric school buses provide[, as well as] the addition of much-needed air conditioning in the new school buses. Until now, only three buses in the district provided air conditioning[….]”

10. e.l.f. Beauty CEO defends DEI: 'Our diversity is a key competitive advantage'

“The cosmetics company recently held that it would not nix its DEI initiatives[….] "Our mission is to make the best of beauty accessible to every eye, lip and face," [CEO] Amin said. "One of the best ways we know how to live that mission is to have an employee base that reflects the community that we serve."”

January 22-28 news here | (all credit for images and written material can be found at the source linked; I don’t claim credit for anything but curating.)

[covid-safer-hotties]

Nasal COVID-19 vaccine halts transmission - Published July 31, 2024

Study in hamsters indicates vaccines targeting nose, mouth may be key to controlling spread of respiratory infections

A nasal COVID-19 vaccine blocks transmission of the virus, according to an animal study by researchers at Washington University School of Medicine in St. Louis. The findings suggest that vaccines delivered directly to the nose or mouth could play a critical role in containing the spread of respiratory infections.

The lightning-fast development of COVID-19 vaccines just months after the virus appeared was a triumph of modern science and saved millions of lives. But for all the good they did in reducing illnesses and deaths, the shots were unable to end the pandemic because of one notable weakness: They couldn’t stop the spread of the virus.

A new study by researchers at Washington University School of Medicine in St. Louis indicates that next-generation vaccines that target the virus’s points of entry — the nose and mouth — may be able to do what traditional shots cannot: contain the spread of respiratory infections and prevent transmission. Using a nasal COVID-19 vaccine based on Washington University technology, approved for use in India and licensed to Ocugen for further development in the U.S., the researchers showed that vaccinated hamsters that developed infections did not pass the virus on to others, breaking the cycle of transmission. In contrast, an approved COVID-19 vaccine that is injected failed to prevent the spread of the virus.

The findings, published July 31 in Science Advances, provide further evidence that so-called mucosal vaccines sprayed into the nose or dropped into the mouth may be the key to controlling respiratory infections such as influenza and COVID-19 that continue to circulate and cause significant illness and death.

“To prevent transmission, you need to keep the amount of virus in the upper airways low,” said senior author Jacco Boon, PhD, a professor of medicine, of molecular microbiology and of pathology & immunology. “The less virus that is there to begin with, the less likely you are to infect someone else if you cough or sneeze or even just breathe on them. This study shows that mucosal vaccines are superior to injected vaccines in terms of limiting viral replication in the upper airways and preventing spread to the next individual. In an epidemic or pandemic situation, this is the kind of vaccine you’re going to want.”

Developing vaccines that can control virus levels in the nose has proven challenging. Viruses such as influenza virus, SARS-CoV-2 (the virus that causes COVID-19) and respiratory syncytial virus (RSV) multiply rapidly in the nose and spread from person to person within a few days of initial exposure. Traditional injectable vaccines generate immune responses that can take a week to build to full strength and are much less potent in the nose than in the bloodstream, leaving the nose relatively unprotected against a fast-multiplying, fast-spreading virus.

In principle, a vaccine sprayed or dropped directly into the nose or mouth could limit viral reproduction and thereby reduce transmission by eliciting an immune response right where it’s needed most. But gathering evidence that mucosal vaccines actually do reduce transmission has proven tricky. Animal models of transmission are not well-established, and tracking person-to-person transmission is fiendishly complicated, given the number and variety of encounters a typical person has on any given day.

For this study, Boon and colleagues developed and validated a model for community transmission using hamsters and then used it to assess the effect of mucosal vaccination on the spread of SARS-CoV-2. (Unlike mice, hamsters are naturally susceptible to infection with SARS-CoV-2, making them the ideal laboratory animals for a transmission study.)

The researchers immunized groups of hamsters with laboratory versions of approved COVID-19 vaccines: the nasal iNCOVACC used in India or the injected Pfizer vaccine. For comparison, some hamsters were not immunized. After giving the vaccinated hamsters a few weeks for their immune responses to fully mature, the researchers infected other hamsters with SARS-CoV-2 and then placed the immunized hamsters with the infected hamsters for eight hours. This first step of the experiment mimics the experience of vaccinated people who are exposed to a person with COVID-19.

After spending eight hours rubbing shoulders with infected hamsters, most of the vaccinated animals became infected. Virus was found in the noses and lungs of 12 of 14 (86%) hamsters that had received the nasal vaccine, and 15 of 16 (94%) hamsters that had received the injected vaccine. Importantly, while most animals in both groups were infected, they weren’t infected to the same degree. Hamsters that had been nasally immunized had virus levels in the airways 100 to 100,000 times lower than those that had received the shot or had not been vaccinated. The study did not assess the animals’ health, but previous studies have shown that both vaccines reduce the likelihood of severe illness and death from COVID-19.

The second step of the experiment yielded even more striking results. The researchers took vaccinated hamsters that subsequently developed infections and placed them with healthy vaccinated and unvaccinated hamsters for eight hours to model transmission of virus from a vaccinated person to others.

None of the hamsters that were exposed to nasally vaccinated hamsters became infected, regardless of whether the recipient hamster had been vaccinated or not. In contrast, roughly half of the hamsters that were exposed to hamsters vaccinated by injection became infected — again, regardless of the recipient’s immunization status. In other words, vaccination through the nose — but not by injection — broke the cycle of transmission.

These data, Boon said, could be important as the world prepares for the possibility that avian influenza, currently causing an outbreak in dairy cows, might adapt to humans and trigger a flu epidemic. An injectable vaccine for avian influenza already exists, and a team of researchers at Washington University is working toward a nasal vaccine for avian influenza. That team includes Boon and co-author Michael S. Diamond, MD, PhD, the Herbert S. Gasser Professor of Medicine and one of the inventors of the nasal vaccine technology used in this paper.

“Mucosal vaccines are the future of vaccines for respiratory infections,” Boon said. “Historically, developing such vaccines has been challenging. There’s still so much we don’t know about the kind of immune response we need and how to elicit it. I think we’re going to see a lot of very exciting research in the next few years that could lead to big improvements in vaccines for respiratory infections.”

Study linked in the first link!

[tarotofhope]

Hi lovelies..🫶🏼♥

I'm Afreen, I'm 29 yrs old. My personality type is INFP. I'm from India.

So, since childhood I've been fascinated by spirituality, occultism and mysticism. I started learning and reading about astrology online, by myself, when I was in high school, but I'm still learning through books as much as I can.

During Covid, thanks to my sis, she introduced me to tarot card readings on youtube because she resonated with a reading by Gem Goddess. She told me I could really do something like that. From then on, I started practicing Tarot after purchasing the Rider Waite deck and then I started my blog in April 2023 on Instagram as well as Tumblr, but due to a huge personal issue, I couldn't continue it. But I knew I had to come back. So here I am..😉🥰✨

Thanks for all your support..🌼🥹🙏🏼

♡ PAID READINGS ♡

I post readings every Tuesday & Friday .

(General readings on Tuesdays & Love Readings on Fridays).

What Good Things are coming Towards You?

Which Major Arcana describes you?

Self-Care Tips For Your Own Well Being

Which Aspect of your Life should you put more Energy into?

What is good about You?

Advice for your Current Friendships (+You as a Friend)

What's your Working Style?

What do your Parents think about You & Why?

What is the Importance of Music in your Life?

What flower do you resemble?

Who is jealous of you?

Your Year 2025- Advice and Predictions

Channelled Love Songs from your Current/Future Romantic Partner

Your Couple Archetype as Plant & Animal Spirit

Why are you Special for your Future Spouse?

First Impressions (Your FS + You)

Your Couple Dynamic as Anime/Ghibli characters

Who is your Secret Admirer?

Romantic Messages from your Lover

The Moment they realize they are in love with you

How do you view love?

Your Couple as a "MOODBOARD"

Your Twin flame Connection

The Office Characters acting like your Zodiac Signs

Astrology Observations: Part-1

Astrology Observations: Part-2

( To be Cont.) ....

Please support by Reblogging, Liking or Subscribing

Follow me on Instagram: @tarotforpeace

——————————— ♡ ♡ ♡ ———————————

[caitchercatlady]

Sleeping Over at Ramshackle w/Idia

Never leaves his room? You take that as a challenge, and you know just the answer to Night Raven College’s biggest riddle.

Idia…I wanna play a fighting game. You down?

Which one? I can connect you.

How about the one you left at Ramshackle with me?

I can literally mod that.

But you can’t eat my freshly baked cookies from your dorm.

(I want it emoji) Fine, you win.

Idia can never resist your baked goods, no matter how hard he tries. He needs them to function on that console of yours.

When he comes over, you don’t expect him to have a bag of spare clothes with him, but you remember that when it comes to gaming, it’s going to be a long night. India immediately goes for your choco cookies.

“Power up!” he cheers after eating two of them.

Then, you two are duking it out for the virtual champion title.

The both of you spend three long hours blistering your thumbs on your controllers. The health bars on the corners of the TV screen are at the chokehold. You and Idia don’t notice how a storm has brewers outside. It’s storming so much that it brings on the thunder. One large crack is all it takes for the power in Ramshackle to drop from fifty percent to zero. India and you take a few seconds to adjust to reality, but you also realize how dark the dorm is without any source of light.

“Good Seven, this would never happen in Ignihyde,” mutters Idia.

You, on the other hand, don’t comment. You point out how late it is instead. You offer to make up Idia’s room as he takes a shower. He might as well. You’ve never had to do this in the dark though. Not that it’s impossible, but your limbs are quaking as you hold your phone as a flashlight under your chin and tighten the sheets onto the spare bed.

You are in the middle of fluffing the pillows when Idia exits the washroom. He peers into the room, watching you shaking like a leaf. He’s all too familiar with the sensation. He clears his throat, alerting you of his presence. You can’t be happier to see Idia in his unexpectedly athletic looking pajamas. The contradiction makes you snicker.

“What? If you were going to catch me in anime tees, that’s never going to happen,” he says.

“Why not? You rarely leave your room anyway. Not like anyone would care.”

“Incorrect. I learned my lesson during my first year. I’ve been wearing my STYX night gear ever since.”

You frown at this. “Sorry.”

Idia suggests that you get a candle or two to light up the place. It would help you sleep better than having your flashlight from your phone beaming in both of your faces. You explain that you tried looking for candles the other day, but Ramshackle doesn’t have any, and Sam doesn’t provide candles unless it’s for the main school building’s events. Idia remarks that he should’ve expected that.

“What? You’re not gonna say anything?” you ask, notioning that Idia knows about your fear of the dark.

Of course, he does, but…“Not really. A NEET like me calling someone like you a baby for a fear of darkness is the most “pot calling the kettle black” scenario some airhead with no creative RPG ideas could ever come up with.”

There’s no argument that you can come up with to combat that.

“As much as I wish I could fix this problem, there is no one-hit solution for that.”

“Gee, thanks.”

“But uh…”

You elevate an eyebrow.

Idia unzips the jacket to reveal a gray, Premo shirt underneath, revealing how Idia still has his interests, but he has told the truth about no anime related clothing. His face begins to pinken, and the tips of his long blue hair fade into blush as well. “I’ve seen this corny thing a ton of times, but I heard it works. If you wanna…then…I guess…”

You carefully step around your bed to prevent yourself from stubbing your toe, and when you are in the clear, you take Idia’s offer to hug into his night jacket. Having you touch him is already nerve-wracking for the introverted Housewarden, but then, to have him wrap you in the jacket folds turns the pale third-year into an overheating furnace. He suggests that you guys hide under the covers before he’d faint onto the floor.

You’re not too pleased with having to turn the flashlight of your phone off, but as you are not alone this evening, both you and Idia suppose that safety is in both of your corners tonight. 

[no1heyyyyyyyy]

Sevika's tastes

Sevika is an old lady and she just wants to be left alone. She likes to look good but when it comes to clothes, Miss thing just doesn’t care that much. She always has practicality in mind. So, no dresses, nothing flowy, has to have natural fabrics so that her skin can breathe, and she requires that things are comfortable. Her shoes are always made for hardware with a strong sole and often reinforced. In the modern world, I see her working in metal working (specifically welding), so she has to have clothes that are multipurpose. Though, if she was forced to wear anything really nice, it would be a simple well-cut blazer and a button down with jeans or slacks that conform to her legs nicely. She prefers earthy colors, nothing too flashy. I think she’d really appreciate a nice dark green, or perhaps brown. I also feel that she would enjoy a nice flannel regularly.

With food, I’m afraid her palette is as unrefined as her clothing choices. She genuinely does not care what she eats, though she really likes chicken- loves hot wings, spicy food is her love. But, her comfort food will always be the food native to what part of India her family is from. I don’t think she’s the best cook, but she has a few family recipes that she knows so well (aloo gobi, chai, samosa, tikka masala, saag paneer). And, I think that on nights where she’s feeling really sad or lonely she always craves those foods. She’d love to cook with or for her partner, it’d be the best way to get to know her honestly. Because it allows for her to show vulnerability through actions and without words. She loves to take care of people and I think in modern times she’d mother her friends just a bit, always making sure they’re eating well, drinking their water, and sleeping right (if not she’ll give them some chai). She doesn’t eat beef or dark meats in general, and she isn’t the biggest fan of seafood or turkey. So, she sticks with her chicken and her paneer. She’ll eat tofu but it needs to be in curry or something similar.

This woman would love 80s hair metal, music is something that I genuinely believe she’d love so much. She’d play drums as a teenager, dead set on becoming the drummer of the next Metallica. She’d also love the old school heavy metal bands, Iron Maiden, Metallica, Black Sabbath, Pantera. She’d love them all. I think she’d like some old school 90s rap too, but none of the new-age mumble rap that’s going on. She wouldn’t really like Taylor Swift’s music, just because it didn’t vibe with her, but she respected Taylor’s ability to get a bag. She has had a huge crush on Adele ever since she heard the album 25 when it came out. She liked some of her music, but thought Adele was drop dead gorgeous and all mature and soulful and shit, hit her in the feels and made her whipped for this woman she didn’t even know.

For movies she loves shitty 80s slasher horror, nothing that makes her think. She’d sit back in her old recliner in her pajamas and house slippers whilst watching Slumber Party Massacre for the third time, and then put on Golden Girls because she feels that Dorothy Zbornak is her spirit animal. She likes a good sitcom too and a ridiculous drama (she loves Desperate Housewives), she likes the camp, the over the top acting and dumb plots, it makes her laugh and feel care free in a way she hasn’t been in a long time. She just wants to curl up with her pets (she would have many) and watch teen-based tv shows that revolve around crime or secrets (Pretty Little Liars, Riverdale, Vampire Diaries, even Buffy etc.). She likes how bad they are, but she gets so invested it’s ridiculous.

For personal scents she’d like more woody, alluring scents that are also kind of sweet. Think Amber by Rag n’ Bone (it smells so good), she doesn’t spray much, just a spritz, it wafts around her just slightly, just enough for women to fall at her feet. Her individual smell wouldn't be overpowering but it would definitely be clear. It’s grounding and soothing. Her sweat stinks though, every time she comes back from the gym, she goes straight to the showers because her own dogs don’t want to come near her b.o.

In general, Sevika is an old woman who couldn’t give less of a shit. She wants to be left alone with her life and her people and chill. Which is why, I feel like she isn’t that opinionated on much unless it’s boundaries or causes she cares about. She just doesn’t have the energy to be bothered with trivial things like which movie to choose for the night, or which restaurant to go to. She is tired and all she wants to do is eat good food with her partner and her pets in a little cottage in the middle of nowhere. She doesn’t like neighbors and she doesn’t like people in her business. She doesn’t need a perfect life, just one that’s hers.

for whatever reason the letters are being weird, it is killing me. Please ignore it.

[reasonsforhope]

Researchers from Western and Brown University have made groundbreaking progress towards identifying the root cause and potential therapy for preeclampsia.

The pregnancy complication affects up to eight per cent of pregnancies globally and is the leading cause of maternal and fetal mortality due to premature delivery, complications with the placenta and lack of oxygen.

The research, led by Drs. Kun Ping Lu and Xiao Zhen Zhou at Western, and Drs. Surendra Sharma and Sukanta Jash at Brown, has identified a toxic protein, cis P-tau, in the blood and placenta of preeclampsia patients.

According to the study published in Nature Communications, cis P-tau is a central circulating driver of preeclampsia – a “troublemaker” that plays a major role in causing the deadly complication...

“The root cause of preeclampsia has (so far) remained unknown, and without a known cause there has been no cure. Preterm delivery is the only life-saving measure,” said Lu, professor of biochemistry and oncology at  Schulich School of Medicine & Dentistry...

“Our study identifies cis P-tau as a crucial culprit and biomarker for preeclampsia. It can be used for early diagnosis of the complication and is a crucial therapeutic target,” said Sharma...

Until now, cis P-tau was mainly associated with neurological disorders like Alzheimer’s disease, traumatic brain injuries (TBI) and stroke. This association was discovered by Lu and Zhou in 2015 as a result of their decades of research on the role of tau protein in cancer and Alzheimer’s.

An antibody developed by Zhou in 2012 to target only the toxic protein while leaving its healthy counterpart unscathed is currently undergoing clinical trials in human patients suffering from TBI and Alzheimer’s Disease. The antibody has shown promising results in animal models and human cell cultures in treating the brain conditions.

The researchers were curious whether the same antibody could work as a potential treatment for preeclampsia. Upon testing the antibody in mouse models they found astonishing results.

“In this study, we found the cis P-tau antibody efficiently depleted the toxic protein in the blood and placenta, and corrected all features associated with preeclampsia in mice. Clinical features of preeclampsia, like elevated blood pressure, excessive protein in urine and fetal growth restriction, among others, were eliminated and pregnancy was normal,” said Sharma.

Sharma and his team at Brown have been working on developing an assay for early detection of preeclampsia and therapies to treat the condition. He believes the findings of this study have brought them closer to their goal...

“The results have far-reaching implications. This could revolutionize how we understand and treat a range of conditions, from pregnancy-related issues to brain disorders,” said Lu.

-via India Education Diary, September 22, 2023

[afeelgoodblog]

The Best News of Last Week - April 3, 2023

Kentucky Legalizes Medical Marijuana in Bipartisan Vote After Decade of Failed Attempts

The state of Kentucky has legalized the use of medical marijuana. The bill received final passage on Thursday. Democratic Gov. Andy Beshear signed it into law Friday morning after a decade of failed attempts in the state legislature.

The news makes Kentucky at least the 38th state in the U.S. to legalize medical marijuana.

Now Indiana is surrounded by weed states. The encirclement is complete 😂

2. The Maryland House of Delegates voted Saturday to approve the Trans Health Equity Act

The Maryland House of Delegates voted Saturday to approve the Trans Health Equity Act — a bill that just a year ago disappeared from the chamber’s agenda ahead of a floor vote.

The bill would require Maryland Medicaid, beginning on Jan. 1, 2024, to provide coverage for additional gender-affirming treatments, which are currently disallowed in the state’s plan but commonly covered by private insurance. The expanded treatments include hormone therapy, hair alteration, voice therapy, physical alterations to the body, and fertility preservation.

3. FDA approves over-the-counter Narcan. Here's what it means

The approved nasal spray is the best-known form of naloxone. It can reverse overdoses of opioids, including street drugs such as heroin and fentanyl and prescription versions including oxycodone.

Making naloxone available more widely is seen as a key strategy to control the nationwide overdose crisis. Effects begin within two minutes when given intravenously, and within five minutes when injected into a muscle. The medicine can also be administered by spraying it into a person's nose.

4. Boston expands tuition-free community college program to all residents

Boston has expanded its tuition-free community college program to include all city residents regardless of age, income or immigration status.

Starting this fall, any city resident will be eligible to pursue an associate’s degree or certificate at one of six partnering local institutions without paying to attend. The program also includes a $250 stipend for incidental expenses each semester for up to three years, and up to $2,500 of debt relief for students whose account balances are keeping them from re-enrolling.

5. First cheetah cubs born in India since extinction 70 years ago

India has welcomed the birth of four cheetah cubs - more than 70 years after the animals were declared officially extinct there.India's environment minister announced the good news, calling it a "momentous event".

The country has been trying to reintroduce the big cats for decades, and last year brought eight cheetahs over from Namibia as part of the plan. Another 12 cheetahs were brought to India from South Africa last month.

6. BBC education show in Afghanistan helps children banned from school

The BBC has launched a new education programme for children in Afghanistan who are banned from school.It is aimed at children aged 11 to 16, including girls whose secondary education has been stopped by the ruling Taliban.

The weekly programme is called Dars, which means lesson in Dari and Pashto, Afghanistan's official languages. It is hosted by BBC Afghan female journalists who were evacuated from Kabul during the 2021 Taliban takeover.

Each new weekly half-hour episode of Dars will air four times a day, Saturday to Friday, on the newly launched BBC News Afghanistan channel.

7. A Trans Creator Has Raised Over 1.5 Million for Trans Healthcare on TikTok Live

Transgender TikTokers are celebrating Trans Day of Visibility by raising over $1.5 million for gender-affirming care around the world.

Mercury Stardust — a DIY TikToker and trans advocate who calls herself the “Trans Handy Ma’am” — raised $120,000 last year in a livestream for the mutual aid nonprofit Point of Pride, which maintains funds for surgeries, hormone therapy, and free binders and gaffs. This year, Stardust and cohost Jory, a.k.a. AlluringSkull, set themselves a goal of raising $1 million in a planned 30-hour live stream…and then smashed that milestone less than six hours after starting the stream Thursday evening.

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[doamarierose-honoka]

Ten years ago, musician Usman Riaz grabbed a pencil and started to sketch.

He might have hoped, but didn't know at the time, that it would start him on a path to making history.

That initial drawing became The Glassworker - Pakistan's first ever hand-drawn animated feature film.

It follows the story of young Vincent and his father Tomas, who run a glass workshop, and a war that threatens to upend their lives.

Vincent's relationship with violinist Alliz, the daughter of a military colonel, begins to test the bond between father and son.

Usman tells BBC Asian Network the characters ultimately come to learn "that life is beautiful but fragile, like glass”.

He describes The Glassworker as an "anti-war film" set in an ambiguous and fantastical world that takes inspiration from his home country.

“I wanted to tackle issues and themes that would have been difficult to tackle if it was based in Pakistan," he says.

The country doesn't have the thriving film industry of neighbouring India and there is no government support or incentive for budding creatives like Usman.

So The Glassworker was a passion project, he says.

“These 10 years for me have just been purely driven with passion and obsession.

“Since I was a child, I have loved hand-drawn animation and there's something so magical about it.

"The beauty of the lines drawn and painted by the human hand always resonated with me.”

Usman says he travelled the world looking for mentors and his search took him to Japanese animation house Studio Ghibli.

The influence of the Oscar-winning artists behind classics such as Spirited Away and Princess Mononoke can be seen in The Glassworker's own style.

Usman says the industry veterans at Ghibli were also the ones who encouraged him to start the production himself.

After raising $116,000 through a 2016 crowdfunding campaign he founded his own studio, Mano Animations.

From there it's been a painstaking process, especially since full production started in 2019.

“What you are watching is essentially a moving painting,” says Usman.

“Every single frame you see, whether it's a background or the character moving, it's all drawn by hand.”

Usman says that, so far, he hasn't made any money from the project and has been unable to pay his wife Maryam and cousin Khizer, who he recruited to help him.

But there's hope that the labour of love could be the start of something bigger.

Usman Riaz says he's always been a fan of animation

Sharmeen Obaid Chinoy is another experienced industry figure Usman turned to for advice about getting The Glassworker off the ground.

She directed 3 Bahadur, a computer-generated tale that was Pakistan's first-ever animated feature film.

On its 2015 release it broke box office records, even surpassing US imports and dethroning previous record-holder Rio 2.

Her studio was also the country's first female-led animation studio, and she understands the challenges of getting started better than most.

“Everything in Pakistan is driven by passion” she says. “I had to run pillar to post.

“We're a country that has limited access to electricity and our industry is heavily taxed.

"We're unable to import computers and hardware needed for animation.”

But Sharmeen – who is going to direct upcoming Star Wars film New Jedi Order – says The Glassworker could be a “monumental step” for Pakistan’s animation scene.

If it finds commercial success, she believes it will “ignite” something in the country, but there are barriers to home-grown animation becoming a red-hot trend.

The Glassworker is partly about the romance between characters Vincent and Alliz

Arafat Mazhar from Lahore-based Puffball animation agrees that “the technical skills are already there” in Pakistan despite there being “no formal training or schools available”.

But “how do you not censor yourself?” he asks.

It's a question facing any Pakistani filmmaker who has to deal with its strict board of film censors.

“Every time there's a good film that comes out that's sincere, the state ends up censoring it,” says Arafat.

He doesn't believe the rules are likely to relax soon.

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Sharmeen agrees the government will only encourage the domestic film industry to grow if they work to "provide opportunity to create a level playing field for us to compete with the rest of the world".

“There is a lot of scope in Pakistan for animation," she says. "We've just never been given the opportunity to create it."

She shares Arafat's pessimism about the pace of change.

"Unfortunately, it will just be a few filmmakers who have that passion, who will continue to create films," she says.

But Sharmeen says she is eager to see how the world embraces The Glassworker.

"I know that there is so much in there that will touch people's hearts," she says.

Usman says The Glassworker has an anti-war message

Usman will finally get to find out how audiences react to the work he's spent 10 years pouring his energy into as The Glassworker goes on general release.

He says he hopes to “put Pakistan on the map” and show it can stand up to the giants across the border in Bollywood.

But he admits the process has been “gruelling”.

“It is extremely difficult, but we've done something nobody has ever done in the country before," he says.

"I think we've created something special that can stand toe-to-toe with the rest of the animation produced in the world.”

Listen to Ankur Desai's show on BBC Asian Network live from 15:00-18:00 Monday to Thursday - or listen back here.