#also dendritic cells

[squidsandthings]

List 5 things that make you happy, then put this in the askbox for the last 10 people who reblogged something from you. learn to know your mutuals and followers. 💚🤎 No pressure btw :}

Aww hihi here's my list :D

1. My Cats (+ My Friend's Cats)

I love my chaos goblins they bring me endless joy and entertainment and they know all my secrets. My cats are my everything even when they eat the foam insulation off my pipes.

2. Dungeons and Dragon's (all my 200+ dice)

I love DND. It's my favorite hobby. Making character, playing in games, impulse buying dice, all things that bring me incredible joy. I love the game I love giving my characters unspeakable trauma it's great. My bank account hates my dice goblin energy tho.

3. French Horn (occasionally)

This instrument will be the death of me lmao. I love horn, and I've been playing for 6(ish) years. It's one of those things that frustrates me to no end, but when my practice pays off and I actually play music good nothing makes me happier. I love horn, I love listening to other horn players, it's a silly, immensely frustrating, super cool, instrument and having the opportunity to play horn as much as I do makes me immensely happy.

4. Drawing :DD

I am not a very good at art person lmao. But I really like doing digital art it's really fun! I like having the ability to make content about my favorite characters or just express an idea i have in a more creative way. Also doodling is just fun lmao.

5. Geese

There was Geese outside my lecture hall today! I love them.

ty for the askkk :DDDD

[heckthis-heckallofthis]

Y'all CANNOT just ship the main!wbcs where is my Friends!ships where are they

[aqqleshiqqing-archive]

Uhm ... Dendritic Cell. In my old art style. Complete with pencil coloring.

Also--he does have the trademark "Sarah falls for characters in suits" thing going for him. I did have a brief outline for an s/i, too--if I remember correctly, she was originally mistaken for a Red Bloodcell, bur was actually a Dendritic one. Don't ask me why--I was ignoring science for ship purposes asdfghjkl

Oh! Turns out I have the ref on my phone, still! Very old style of mine, but like. She!

~ librarian-lover 📖

"I was ignoring science for the ship" WHAT A MOOD. REAL MOOD i mean rbcs die pretty quickly in the body but NAWWW that doesn't happen here <3

HE LOOKS SO CUTE OH MAN I MISS HIM SOOO MUCH 🥺🥺 HIS ACTIVATED DESIGN MY BELOVED!!!

the whole idea that your si was mistakened for an rbc... that's so adorable love it 10/10

the leaves in her hair is super clever, and pretty 🥺🥺

[doodlepede]

hey Rain World fans. I'm gonna show you a lore interpretation that I personally have never seen anyone talk about except myself. If you know me as Sliverist, then you know what's up.

Everyone knows the first five Karma glyphs represent the so-called Five Natural Urges. Violence, reproduction, trade and social connection, eating, and self preservation. People generally believe the next Karma glyphs before the tenth are meaningless, but this is WRONG. Understanding this revelation requires seeing the big picture, which I will guide you through.

Rain World really likes to blur the line between organic and inorganic, with the most obvious example being the Iterators themselves, these biomechanical superstructures whose function in large part is outsourced to their "microbe strata" (Purple SL pearl), but it goes even further, into the very world design.

Five Pebbles' internal structure resembles a brain with its many sections all divided into specific regions with specific purposes. His chamber makes the resemblance even more obvious, where you can clearly see the brainstem.

Within Five Pebbles' dark interior swim swarms of colorful neurons which turn white in broad daylight, each one a carrier of information. Often, they are brushed along by cilia lining the computer halls.

The Void Sea writhes with a swarm of beings enormous beyong reckoning which closely resemble real neurons. The void worm that takes interest in the slugcat uses a dendrite to make a tether to drag the slugcat to its final destination.

As the slugcat swims and swims, it is joined by countless many just like it, and together they swim toward the light, referred to in the code as "TheEgg" (VoidSeaScene.cs)

This is the table of Karma, showing every level above Five. Doesn't it look rather like..

dividing cells being crossed out?

In Rain World, birth and life, cognition and enlightenment, death and ascension are all inextricably connected concepts. You might even say they're connected in a cycle. The imagery and themes are rich and complete, integrated fully into the world. This is even without mentioning the voidspawn which also resemble sperm, swimming to the same place. This is why Ascension is the best ending :artiyoy:

[proxentauri]

when i saw @n0rtist's ability forms i had to do reuniclus.....i hope it's not too late to be featured in the video! :0 we may have crossed from ability form into actual alternate form territory (see the original colours below the cut to see how crazy different they could have been)

as someone in evo microbio this was insane amounts of fun to do and i was able to pull inspo from places i'd never think to reference in my regular art!

itemized essay explaining the science and my design choices in more detail below the cut:

Ability Form 1: Overcoat

The science

Based on bacterial biofilm, which is basically when a bunch of bacteria get together in the same spot and start excreting this sticky slime stuff that structurally keeps the bacteria together (and also act as a medium for sharing useful resources between the bacteria, like enzymes, nutrients, etc.).

The design

The strings connecting the bacteria is based on what the slime stuff looks like on a microscopic level, specifically in electron micrographs like this one

The violet colour of the (rod) bacteria in the biofilm is a reference to Gram staining, which is a type of bacterial stain used to classify bacteria into two groups: bacteria that contain peptidoglycan in their cell walls (which stain violet) and bacteria that don't (these stain pink). Peptidoglycan is this pretty chonky polymer compound that's used to strengthen bacterial cell walls, so I thought it fit the role of Overcoat (which protects your Pokémon from things like weather)

Ability Form 2: Magic Guard

The science

Based on the myelin sheath, which are these segments of tube-like insulation that surrounds your neurons (see picture here). Mostly people talk about how it makes your neural signals propagate faster, which is true, but this ability form was more of a reference to its general protective role; it physically and electrically insulates your neurons. (Surprisingly I could not find a super good primary source for myelin providing physical protection, so don't cite me on that, but given it's literally a physical barrier this seems like a pretty safe assumption.)

The design

The entire body is based on a pseudounipolar neuron, which just means it only has one part extend out of the main body but shortly after it splits into two long parts (axons). I could have made it a bipolar neuron I guess (two parts extend out of the main body), but having a neck made it look a little closer to the base form's body

I wanted to give it dendrite fingers but it looked too creepy. I'm not sure if the three long fingers I gave it in the final design made it less creepy.

Since Overcoat and Magic Guard are both shield-type abilities, they're drawn as more closely related on the the phylogenetic tree (white thing in the center).

Ability Form 3: Regenerator

The science

This one is the most hype imo. In 2015 Dr. Will Ratcliff did this pretty sick experiment about the evolution of multicellularity (since at some point a long time ago life was single-celled) where he kept propagating the same single-celled yeast for a mega long time, and eventually the yeast evolves a multi-cellular "snowflake" form where after undergoing mitosis, the resulting daughter cells don't split, but stay attached, resulting in the yeast forming these clusters that create these cute little branches. I don't know where I was going with this. Oh right, the branching out reminded me a lot of regenerating limbs, so that was the inspiration for this one.

Anyway this is like one of my favourite experiments ever, there's some pretty good news articles out there about if you want to learn more about it!

The design

The segments are yeast cells, and the balls within are the nuclei.

The colour scheme was based on this fluorescent microscopy photo of the snowflake yeast. Originally I had the nuclei be bright orange in reference to this other microscopy picture but I thought the colour scheme was deviating too much from the base form for an ability form lol.

Speaking of here's the original unhinged colour drafts:

if i did commit to the full alternate form i think the biofilm one is poison, myelin one is fighting, yeast one is uhh...dude idek, i mean the fluorescent microscopy vibe is pretty strong so maybe electric lol? it's giving ghost vibe too though

i was originally planning on citing stuff but it's a tumblr post and I've already linked Ratcliff's work and i want to go to bed lol. If any of the science is wrong just call me out i'll fix it. otherwise, i hope someone out there appreciates the science references !! it's 8am good Night

[lumiistar]

mast cell bc she’s literally me

I’m bored, reblog with your favorite cell. Mines the macrophage in Lady.

[strawberrysnoopy]

ACT ONE: The Photo Shoot, part one

prologue

summary of the series: for months, leon has been writhing in his bed dreaming of his friend's wife (you). he's been fighting the desperation for months until that one night you bring up a lingerie shoot you've done for a prestigious brand.

summary of this part: recalling the first time you and leon met, you've realized you've been poorly treated by your husband. leon is no different, in a toxic relationship with his wife, ada wong. as the seeds of resentment have begun to germinate, the desire for you grows like a brush fire nearby.

warnings: MENTIONS OF PUKE, BUT NOT ACTUAL PUKING, leon teaches you how to smoke (i don't wanna see no dumb stupid comments about "oh but leon hates smoking", well leon isn't disloyal but here we are), brief use of (adjective) girl (atta girl, good girl, silly girl), praise, mentions of misogyny (not from Leon ofc), awkward, tense ass convos, a fuckton of desc. and a little description, no sex (yet ;) ), cussing, descriptions of fucking, descriptions of masturbation, semi-public masturbation, almost caught masturbating, slight corruption kink (? if you squint), alcohol consumption, use of tobacco, smoking, implied sexual references, etc.

also a/n, writing this as of feb. 2nd, 2024: 60 notes?!!!!! i was writing this for my own personal pleasure but like...??!?! i got reblogged so many times?! im gagged, tysm you guys!!! making a playlist rn, so excited to release the soundtrack. if you see little random edits, i'm probably obsessing over the fic and trying to make it perfect lol/anticipate changes. i would also like to write I DO NOT CONDONE CHEATING! always communicate with your partner, discuss issues, etc. this fic is just a lil’ taboo type of fantasy, do NOT cheat on your partners.

The first time you met Leon was at a grocery store: two weeks before your husband would have any idea of his existence and one week before he had invited Leon and his wife, Ada, over for dinner. You were picking up a bottle of red wine for you and your husband under the guise of wanting something nice for date night. The reality would actually be you were buying it for yourself after your husband decides you're not worth his affections anymore, lazily mosey on over to the spare room, and pull out his phone to text other women. The wine would be something to drink to inebriate you while you watched a shitty re-run of a sitcom from the 90s. Maybe if you got lucky, Golden Girls was on.

He was only browsing, stumbling upon the liquor section and staying to look if there would be anything worthwhile. And there was. It was you. He knew he had to think of something witty, something cool people say, before you left and thought he was some creep staring at you because he saw a smidgen of your breasts in a magazine. "You're a famous model, right?" He asked. Oh, how stupid he felt. He was a chronic overthinker: thinking of every last terrible scenario, a trait he picked up after becoming an agent. This had certainly felt like one of the worst options he picked, especially with how you would-- You interrupted him. "Yeah, that's me." The subtle sweetness, the slight rasp in your voice was better than anything any street drug could offer with the amount of dopamine flooding into his brain: overloading every neuron, synapse, dendrite, and cell membrane in his body.

But for whatever reason, he stretched his hand outwards and lazily grinned towards you. "I'm Leon." "Nice to meet you. Well, I'd say my name but y'know..." He nodded in an awkward agreement before you could even finish your sentence, but not daring to go as far to interrupt you. He felt as if he already started off the conversation with a cumbersome beginning. "Right, right. So, that's your real name? I see a lot of models use stage names n' stuff like that." He adjusts his weight from one foot to the other, switching the hand holding his grocery basket from his right to his left. He felt so...awkward around you. Maybe it was the fact you were a famous model, or maybe it was the fact you were just so calm. The joke causes a soft chuckle to leave your lips and the mere look of a fleeting moment of bliss to cross over your features makes his knees turn into gelatin. Those nerves solidify into stone when the overwhelming sense of guilt hits him like a tidal wave but allows it to wash over him for the sake of continuing the conversation.

"Yeah, just my regular name. I'm not that creative outside of modeling. Usually the photographers do the thinking and the creative processes for me." He chuckled, shaking his head and barely moving himself a little closer. Leon wanted to sink in that gentle, warm, and soft presence you carried around with you. Your aura felt comforting: like a hug after a tough day: it had felt so much more different than his wife. True, Ada could be affectionate but that's usually only after something good has happened to her or Leon was her last resort of attention. He really hated how much he would act like an obedient dog, awaiting her arrival home, coming back to her after she's treated him like dirt. You? You felt so goddamn altruistic and considerate. And he's only known you for three minutes.

You notice he's gone silent and you're silently hoping he thought you were cool. Cool. Like a teenager trying to fit in. You silently cringe at yourself until he smiles at you, almost like he's signaling you to continue the conversation. You can't think of any conversation starters. And you're a model for gods sake. You're usually so outgoing and social with other people but now it's like a cat came by and stole your voice box. Thankfully, he takes over that portion for you. "Buying wine?" He knew it was dry as all hell but he wanted to steer the conversation away from him being a fan of your modeling gigs. No, he just wanted to talk to you and discover what you were like behind the camera. (Okay, and maybe he wanted to see if you'd flirt with him.) "Yup. But I'm just buying wine for..." You paused, about to say 'for me and my husband' but your throat becomes dry whenever you feel like you're about to announce it to him. "...Myself."

He smiles. He likes that you're awkward in real life. The fact made you feel more real, like you weren't just some sexy model with expensive tastes and a bratty attitude. You were a person like anyone else.

"Right. Me too, just uh...just browsing." You nod, fidgeting anxiously with the sleeves of the coat you decided to toss on last minute before leaving the house.

The conversation went on to end when you eventually realized you would be home late. Although you thought that worrying your husband a little would be the thing that reignited the spark in your marriage, you knew that punctuality was a habit you'd like to upkeep. That, and you also knew if you talked to this handsome stranger for longer, you'd cheat on your husband. That night, Leon had fallen asleep to the thought of you for the first time. Soft little visions of pressing his lips against yours, caressing your cheek softly and whispering sweet nothings into your ear, etc, etc, cheesy lovey dovey bullshit. So much more different than the truly filthy thoughts he had about you nowadays. You're torn from your conversation with your friends when you make eye contact with him. You can practically feel his eyes travel from the hair at the highest point on your head to the very last bit of your black, leathery heels with perfect pretty pearls embellished on the pump. For a moment, you feel like you're trapped in some type of horny labyrinth while you stare longingly at him.

He's ripped out of his own longing by the feeling of your husband's hand slapping his back. Ada sat beside Leon with her arm protectively wrapped around his bicep. You felt as if the gesture were a signal to everyone at the party that Leon belonged to her. He was under her control, nobody else's. Or maybe the protective message was for her husband, as if he was an unruly friend to her husband. And you could agree with that. You fell in love with your husband because he was wild and care-free but after the diamond ring was slipped onto your ring finger, you realized he was also carefree in the sense that hurt you: talking to other women behind your back, and leaving for days at a time only to come back inebriated. But you stood by his side, no matter what. You hated how you felt like a doormat but you didn't know what else to do besides stay married and play the role of an oblivious wife while your husband fucks other women in various positions. In a way, you and Leon sat in the same loveless boat. Who knew when that same boat would be shaking from the violence of the both of you fucking, clothing pulled out and to the side instead of being fully taken off. Your thoughts become interrupted by an unmistakably handsome voice.

"Hey."

You feel a hand being placed upon your lower back except it's so much more different than your husband's. The palms were rough, callouses inside the nooks and crannies, and pulsing veins make you all dizzy if you thought about it for too long. His voice was dampened with some undertone of lust, his fingers prodding into the skin of your sides. He's always been a little too handsy for a man that's supposed to happily married. But you always figured touch was how he communicates: touch. But he's never touchy with your husband. Or any of your friends. And he missed you? Sure, your're friends due to the fact your husband was friends with Leon. (Even though you met him first, but I digress.) The simple phrase had your mind reeling, cheeks flushed red due to the hidden intimacy of it all. His wife shoots him a look and his hand immediately retreats back to his side, fighting the urge to palm the engorged erection struggling against the seam of his boxers. "Haven't seen you in so long, hm? Thought you disappeared on me for a minute." He's holding his facade of being totally and irrevocably in love with Ada up and steady. Like he had no feelings for you other than being friends.

"Of course not." You murmur, feeling a hearty chuckle reverberate from his chest. He takes his index finger and his thumb and gently swiping it against your chin.

"Atta girl." And of course, with how hoarse his voice is, your panties are instantly puddled with a thick pool of arousal. You hate his stupid, thick, sexy, and deep voice. You especially hate his voice whenever you imagine him degrading and praising you whenever your husband was away and you just happened to have your hand down your underwear, playing with your clit to ease the throbbing impulses you felt for Leon. He gives your back a single pat before moving back to stand beside his wife. You really hate that you feel jealousy flare like wildfire within you, but you brush it off.

Everyone would eventually be drawn to the several dining tables that were arranged in a group and had golden candlesticks and smooth white tablecloths on top. Once you are seated, you observe that Leon appears to be striving extra hard to guarantee his place beside you. He looks right at you for a brief moment. And only then can you see, just a hint of thirst sprouting in his eyes, before he glances away from you and gives Ada a quick smile while patting her thigh.

It's only a few minutes before Leon decides to break the awkward silence.

"How's that modeling gig going?" You nod, gulping down way too much champagne.

"Good, been going good. Have to admit it gets a little boring posing in front of the camera after a while but can't bite the hand that pays you, right?" You joke, and the table laughs with some sense of jealousy. "Nice to hear. What was your latest shoot?" He asked, leaning forward in a sudden rush of intrigue. Then those words pass your lips. Words he had never anticipated, even in his wildest guess (oddly.)

"A lingerie shoot. For Chanel." The table goes quiet. And everyone, including your dumb-ass husband, look at you. Someone (Ada) clears their throat in the dining room, hinting at you to elaborate and it's almost like you suddenly developed to ability to hear from light years away.

Leon, who had just finally got his goddamn boner under control feels his cock twitch back to life, fully hard instead of a semi this time. And correct him if he's wrong, but he starts to feel pre-cum smearing his dress pants. He's thankful he chose the black slacks instead of his lighter colored ones otherwise this would be downright humiliating.

"Sorry, um...I did an intimates photo-shoot for Chanel a few weeks ago for their new line of clothing." That seems to help lighten the mood a lot more because everyone goes back to their conversation with their respective friends, the embarrassing "confession" from you immediately leaving their minds. "The theme was Overtime. Like, staying later in the office with my shirt unbuttoned and stuff. Nothing that interesting."

The table simultaneously nodded, Leon going as far to excuse himself for a cigarette.

"If you'll excuse me, I'm gonna go have a smoke." Leon scoots out from his seat, heading towards the upstairs balcony to take care of business. Asshole, leaving me with his mean ass wife.

You decide to join him outside.

The air had finally gotten too tense, felt too judgmental for your taste. Scampering outside, you're met with the sight of Leon smoking a cigarette outside. That's odd: you've usually pegged him to be the straight-laced, no-nonsense type of man yet here he was, smoking a cigarette while leaning against the balustrade of their friend's top floor home. At the sound of the balcony door opening, he turns his head to see what you're doing out here. His eyes scan you, almost like he would while he's in combat but it's more or less to get another glimpse of the outfit you were wearing tonight. Okay, and maybe he wanted to commit the sight of you to memory.

"You alright?" He asked, trying his best to look straight forward when you step closer and cross your arms over the balustrade.

"M'fine, just needed a minute of fresh air, I think." When you sit beside Leon, there's a few things you notice. The first was his outfit. A white button-up that usually would be covered by his black suit jacket, though he left it behind on his chair in the dining room. There's also mentioning his blacks slacks, fitting his muscular thighs a bit tight but loose enough so they're comfortable. Then there's the dress shoes, ones he wore at his wedding due to how overly formal they looked. Maybe he wanted to get some more use out of them? Who knows.

"What about you? Why are you out here?" You decided to be the one to take the reigns since the air outside had become incredibly awkward as well. "Same. Thought I'd take a minute of fresh air, you know?" The second thing you notice about Leon is how much he calms you. More importantly, how much you never noticed that you were anxious when you were around others. He had this aura of relaxing or maybe you were just buzzed, who knows that either? Maybe it's the cigarette, speaking of...

"I haven't smoked since college. Cigarettes, I mean. Don't think I even know how to do it anymore." The confession makes his head tilt to the side, now taking more of an interest in the conversation than before. He grinned wolfishly, taking your chin in one of his thick and strong hands and pulling your head forward. For a second, you could almost be dumb enough to think he'd be moving in for a kiss. Of course not. You'd never be that lucky. "Open f'me, sweetheart." And like an obedient puppy, you opened your mouth just enough so your pretty pink-shaded lips could be parted. He placed the cigarette on your lip, the moisture making the filter stay in your mouth alongside his index and middle finger holding it up, thumb brushing your chin. Little hazes of grey smoke dance along your tongue without even taking a sip of the smoke yet, your lips trembling with a lustful agony. "Now close your mouth..." He whispered, his damp and hot and horny breath hitting your ear like an affectionate declaration of love. "And inhale."

You close your lips around the cigarette, faintly tasting the flavor of him where he had sucked on the cigarette. You got notes of citrus, rum or some expensive, top-shelf label of whiskey he used to help quell the pain he experienced on grueling missions, tobacco, and maybe even the slightest hint of his wife's lipstick. Chanel's Rogue Allure, if you had to guess correctly. "...Now hold it..."

You held it. "Silly girl." He whispered, pulling the cigarette away from your lips while you slowly exhaled the rest of the smoke you've been holding in your mouth and then some. You can't tell if it's because of the alcohol, Leon's presence, or your mere anxiety but you begin to feel dizzy. Thankfully Leon seems to swoop in with his questions to keep your head in the game. Bless him.

"Why'd you need a minute, huh?"

For a minute there, you didn't know how to respond. Looking down at the leathery pumps you chose for the evening, you begin to wonder why you even chose them instead of answering his question. But you answered him. Eventually.

"I'm just tired. This whole night just seems a bit…” You gesture to the party in the background. “Fake. I don’t want to be here."

He hummed in agreement, but it felt like more of a signal for you to keep going. "I'm also just terrible at making conversation. Especially when it's awkward and silent."

His eyes flicker down to the pumps he'd already stared at tonight, not finding an interest in them anymore than your own body. He tucked his lip between his teeth, pulling the pink flesh away from his mouth before he spoke up again. "You're not that bad, you know? I think you're pretty good. How about this?" He pauses. Then a beat passes.

"Tell me something true. Tell me something you wouldn't brag to anyone about." He moved his cigarette to rest on the balustrade instead of the space between his fingers. "Something that's yours...and only yours."

You look at Leon with wide eyes, mouth agape as you struggle to answer his question. Your eyes rake down his face from the space between his eyebrows to his parted, pink lips: just a little chapped from the cold chill of the night air. You wanted to kiss him. All of those times you've had him over for dinner, all of those times you've spent with your hand down your panties while your husband was away on "business": dreaming of his best friend, Leon, and god, all of those times you thought about throwing caution to the wind and leaning in to press your lips against his: the sum of all of those moments had you quivering for more.

But you'd never cheat. You have a reputation. You have a husband that gifted you the pretty diamond ring on your finger. But how did it always feel so...impossible? Like you couldn't live another day if you weren't able to fuck Leon like a rabid dog in heat. But he was staring at you, almost as if his eyes were laser beams and searing holes into your skin: you had to answer.

"I don't know what I could tell you that's only mine." You chew on your lip. "Huh. How about..."

How about the fact I wanna kiss you? I wish it was you I was in bed with rather than my stupid, cheating husband? The fact you are so much hotter than him?

"I hate being a trophy." And that brings the biggest grin on Leon's face. A massive shit-eating grin. Leon had gone stir crazy. He wanted to peel your entire being open, see all of the nooks and crannies of your soul and devour it whole. But now wasn't the time to scare you away: even if he wanted to fuck you, you were still a friend to him. So he calmed down. "I can't say that's too surprising. I mean, who would? Being able to be pretty and have money being tossed at you is nice until you want something deeper. Then it seems like one of the only things that are scarce in your life."

You nod, letting out a breath of consolation. "That's exactly how I feel. Like my only purpose is to sit still, look pretty, serve my husband, and be a hole when he needs it."

His eyes become downcast, looking down at the garden on the ground level of the restaurant. "I get what you mean." The moment was interrupted by a waiter peeking out on the two of you: head poked outside of the door that lead to the outside area. He pulls his hand away from your soft skin and back to his side, sighing wistfully that tonight wouldn't be the night he gets to act on his desires for you. Damn it all to hell.

"You should head back. I'll be back, yeah?" You nod and within a few seconds, you've returned to your spot at the dinner table. He sighs, hand slipping down to palm at his erection. Fuck. Can't go back like this.

Just resist. You're just another woman. You have a husband, He thinks to himself, I'm married to a lovely woman. I am a faithful husband. The silent mantra he practices on himself works about as well as a band-aid on a bullet hole. Resist. God, but you looked so pretty tonight. That cute jewelry set you wore with your little black dress? Hot. The smoothness of your skin?

Resist.

But he can't stop picturing you on your knees in front of him, sucking on his cock. The sounds your perfect, wet mouth would make. How he'd ease himself down your throat. How you'd whine.

Resist.

Or how about when he could be fucking his cock into your tight, wet, and warm cunt? The tip of his dick kissing your cervix? Or what about the positions he could force your body into? Like having his arm around your throat, bicep curling into your mouth to muffle your moans from his wife hearing? Or how one of his hands would be gripping your hips while he needily plowed into your pussy, while you begged him to let up. Resist.

Resist.

Fuck it.

In the few moments after he's excused himself from you, he's already rushing to the upstairs bathroom of the restaurant: thanking the holy beings above for making it a single stall bathroom for his jerking pleasure. He hastily unbuckles his belt with one hand, other hand impulsively opening Twitter as a first resort to find some fashion fanatic post about the slutty lingerie photo-shoot you did for Chanel. Alas, you're still a bit of an undiscovered goddess in the modeling industry at the moment: so Google is his next best option. He pulls out his half-hard but hardening cock from his jeans before he can even find your photo-shoot and gives it a quick few pumps to ease the throbbing that's starting to build up in his loins. Eventually, he finds it. Thank fucking god because the creativity for his fantasies are beginning to run quite dry. And instantly he's grunting and groaning while he strokes his cock and scrolls through the multiple scandalous photos the photographers took of you.

"Fuck." He winces in pleasurable agony as he stares at quite possibly his favorite photo of you. The photo was in black and white: theme being "Overtime" like you mentioned. The white button up shirt was undone, revealing you had nothing on underneath, and allowed for the side of your perfect breasts to be revealed. If he squinted just a little harder, he could see your puffy nipples threatening to peek out of the shirt. He tried squinting a little harder to see your nipples a little easier. And oh my god. You have piercings?! He almost shot his entire load on the spot. God, he needed to fuck you. And hard. He groans as he feel himself get closer to orgasm. Closer, and closer, until--

"Leon?"

Fuck. It was you. God, of course you're so goddamn sweet, checking up on him to make sure he's okay. He didn't dare stop stroking himself off, especially not when he's got jerk-worthy material of you almost catching him. That's also not mentioning the soft intonations of your almost innocent voice right there. He's trying not to cum too quick, wanting to savor those images for as long as he could but he also realized his wife might start asking some questions and she wouldn't be on the other side of the door if she came upstairs. "F-fuck, yeah?" He responded after much too long of hearing your sweet voice. "Did you need something?" "Are you okay? I just got worried when you left. You've been gone for like..." You check your wristwatch: a classic and dainty Timex from the 80s with a blank band that wrapped around your wrist snugly.

"Fifteen minutes. Do you need water? Ibuprofen?" He shakes his head as if you could see him while he continues to jerk himself off, hand swirling in a sort of cranking motion as he tries to work his cock to orgasm. But his pre-cum isn't coming out fast enough, not as fast as the pumping motions his hand was doing right now, so he spits in his hand before bringing his palm back down to his cock and lathering his dick in spit. You believe him enough to think he might be getting ready to vomit.

"Nah, jus'...ngh, drank too much, I think." Please keep talking, He selfishly thinks to himself. "Oh, okay. Well, if you need anything, just text me?" He nodded, grunting out a thank you while he continues to dream of ruthlessly fucking you until you're embedded into his mattress. He wants you. He needs you. He feels himself get a little closer until he finally releases into his fist. His hot and sticky cum ran down his palm while the waves of post-orgasmic bliss and post-nut clarity simultaneously moved together as one. For a few minutes, he's panting like a rabid dog in heat until his breath eventually stills and he's able to walk downstairs and look his wife in the face while giving her the impression that he definitely didn't just masturbate to his best friend's wife. When he sits down at the table, the first person he makes eye contact with is you. You smile at him, mouthing a "you okay?" because, of course, you're still worried about him being sick. He nods with a grin peeled onto his face. Because he came to the sound of your voice. And you didn't have a fucking clue.

credits: snoopy divider by @animatedglittergraphics-n-more heart divider by @saradika-graphics

[planefood]

Funnie Blood drawing Also Blood interacting with a dendritic cell

[equipment-manifest]

What do you think of these axon looking things?

Given the similarities to axon terminals I was wondering if they were for delivering information/status report of their surrounding equipment

But the one at moon's gravity disruptor feels more like its sampling data from the engine (the last few times I went through that room it ragdolled very hard upon entering due to the gravity lol)

And looking at that screenshot I just took from the map website, it also has the "reading halo", so it probably is catching on information rather than relaying it

Ah, these things - there's not a lot to go on with them, but they're certainly interesting. I'm going to use the game's internal nomenclature and call them "coral stems" for clarity.

Coral stems seem to interact with an Iterator's internal biota in much the same way as their more common cousin, the wall mycelia. Both organisms sprout from the Iterator's internal walls, attracting to their hyphae neuron flies and the free-floating hyphae of coral neurons and inspectors. The sparking effect produced upon contact with these organisms is identical to that seen between interacting overseers, so I'm inclined to believe it represents the exchange of information (rather than say, energy or nutrients) between an Iterator's stationary machinery and its free-floating organic parts. The question then is how the role of coral stems in this interface differs from the role of the wall mycelia.

As you implied, the segmented body of a coral stem closely resembles an axon wrapped in a myelin sheath, the part of a neuron that transmits signals away from the cell body. In such an analogy, the cell body would have to be the machinery the coral stem is anchored to. The wispy mycelia growing from that machinery would then seem to fit the description of dendritic branches, thin growths that receive signals from other cells. So one interpretation could be that the coral stems and wall mycelia perform opposite functions, delivering messages to and receiving messages from the free-floating biota respectively.

Another possibility is that the wall mycelia and coral stems are both sensory organs, but with complementary roles. The mats of wall mycelia are not especially dense, but their hyphae extend into a large part of an Iterator's internal spaces. This makes them well-adapted to sensing macroscopic organisms like neuron flies or coral neurons. These organisms are unevenly distributed in a way that requires hyphae to be able to reach them no matter where they are in a room, but their large size and weight ensures that any nearby hyphae will certainly be disturbed by their presence and brushed against them. In contrast, small particles like microorganisms or chemical traces in the air would be unlikely to collide with the scarce hyphae of wall mycelia, and too light to be reliably detected when they do.

The bundled hyphae of coral stems could act like scent traps for these particles—when one happens to wander into a coral stem's bristles, it's likely to become trapped and bounce around among the dense hyphae for a time, the repeated collisions ensuring that there are many chances for it to be detected. Of course, coral stems are distributed much more sparsely than wall mycelia, but that would be just fine for this purpose. Diffusion ensures that the distribution of small, light particles is relatively homogeneous throughout a space: the air in one part of a room is about the same as the air in any other part, so there'd be no need for too many coral stems close together.

I hope this provided some food for thought, thanks for the ask!

[humancelltournament]

Human Cell Tournament Round 1

Propaganda!

In molecular biology, CD4 (cluster of differentiation 4) is a glycoprotein that serves as a co-receptor for the T-cell receptor (TCR). CD4 is found on the surface of immune cells such as helper T cells, monocytes, macrophages, and dendritic cells. CD4+ T helper cells are white blood cells that are an essential part of the human immune system. They are often referred to as CD4 cells, T helper cells or T4 cells. They are called helper cells because one of their main roles is to send signals to other types of immune cells, including CD8 killer cells, which then destroy the infectious particle. If CD4 cells become depleted, for example in untreated HIV infection, or following immune suppression prior to a transplant, the body is left vulnerable to a wide range of infections that it would otherwise have been able to fight.

In cell biology, a vesicle is a structure within or outside a cell, consisting of liquid or cytoplasm enclosed by a lipid bilayer. Vesicles form naturally during the processes of secretion (exocytosis), uptake (endocytosis), and the transport of materials within the plasma membrane. Vesicles perform a variety of functions. Because it is separated from the cytosol, the inside of the vesicle can be made to be different from the cytosolic environment. For this reason, vesicles are a basic tool used by the cell for organizing cellular substances. Vesicles are involved in metabolism, transport, buoyancy control,[2] and temporary storage of food and enzymes. They can also act as chemical reaction chambers.

[iepurasdepraf]

Lights Out Pt. 2 - Enjoy

"The elaborate branching structure of the dendritic tree allows a neuron to receive inputs from the other neurons through synaptic connections. The cortical pyramidal neuron of figure one point one A and the cortical interneuron of figure one point one C each receive thousands of synaptic inputs, and for the cerebellar Purkinje cell of figure one point one B the number is over one hundred thousand. Figure one point one does not show the full extent of the axons of these neurons-" 

You had to blink. Hard. Had he breathed in the last thirty minutes? You weren't sure. You weren't sure if you had either. 

Initially, you'd managed to understand what he was talking about, but over time that had slowly waned and been overtaken by a sea of information that just kept rising. It started bleeding together in your head and your eyes were burning from squinting at his cracked phone screen where he was showing the arithmetic and diagrams. You’d gotten at best a D or C in math. You couldn’t remember anymore, but you’d passed. That said, you certainly weren’t built for this. 

“The electrical signal of relevance to the nervous system is the difference in electrical potential between the interior of a neuron and the surrounding extracellular medium-”

Not wanting to be rude since he was paying for your time, you raised your hand and were quickly called upon by your impromptu professor with nothing, but delighted glee on his face that you were even listening “Yes!?” "Whereabouts in this presentation are we?" "We're just about through the first half." "The first half?" Dear God in Heaven. 

His nose scrunched up a little exposing his buckteeth even more, he must have caught on that he was frying your brain in its pan. Maybe he found it funny. "How many parts are there?" You asked, trying your hardest to sound amused and not tired. "Five! Well, five and a, ah... sort of post note." You laughed a little restlessly and sat up on the sofa. Legs long having gone numb from being in one position for so long. 

He held up his flashcards, smudged as they were from his sweaty hands. "I felt like I needed at least eight parts to fully explain, but I ran out of cards." "Why not buy more cards?" His hand lowered as he thought about it "I- Well, I suppose I... didn't want to admit my poor foreplanning?" You press your fingers to your eyes for some relief. It didn’t help and that didn't make sense, but nothing had since he stopped stuttering. Sure, the words were coming out now, but that didn’t mean they made sense even with his extensive explanation. If anything it was making it worse.

Your hands fell to your lap as you asked “Who are you giving this presentation to, Jervis?” He turned red when you said his first name. You could tell it was that by the way his eyes fluttered. It was like every now and then he remembered you were a pretty lady giving him the time of day and it staggered him a little. “The-The board. Well, I- let me explain.” He sat on the edge of the small stage you’d made him stand on when he started this whole thing. “I don’t do things like this, you see. I’m a lab rat through and through. I haven’t given a-any kind of presentation since I defended my thesis for my doctorate.” 

There was something wrong with you. That was actually impressive and you nearly asked what his thesis was about, but you also wanted to go home before five. “I work for Wayne Enterprises and normally I’m kept down in the basements- they keep all the non-theoretical work in the basements for security reasons... I shouldn’t have told you that.” He laughed his anxiety spike off in a concerningly manic way again and all you could think to do was nod in response, nearly used to it at this point. That or you were so tired you were just accepting it for the sake of what was left of your mental bandwidth. “Recently, I don’t know why for certain, but they’re- Oh, how did Dr. Kates put it? Doing an internal audit of ongoing research to access security, costs, and productivity. I suspect someone was caught misusing grant money or they suspect someone is.”

“Is someone?” “Heavens no!” He dismisses the very idea with a flick of his wrist. An oddly elegant gesture for someone so tense, but that was likely the liquor in him. “They barely give us enough to keep the power on in the labs. If someone was doing that the flickering lights would have surely let us know long before accounting noticed.” Jervis rolls his eyes grumbling, “Useless things they are. Still haven’t approved of my new slides.” He was getting distracted so you lean forward to get his attention. “Why would them thinking someone’s stealing money have you doing a presentation?” 

He blinks like a toad, eyes unable to settle on just one part of you until he registers you are looking at him and you know that so he looks away instead, fumbling with his cards to try to get his train of thoughts back on the rails. He didn’t succeed right away. “I…They-well, they- um…Hm.” Jervis clears his throat “T-t-to prove I am making progress.” Your head tilts slightly to the side “Would they be able to tell?” “What?” Your simple question seems to knock him out of his self conscious stupor. “Well, you’ve written a really detailed presentation, but are the people you’re going to be presenting it to, will they understand what you’re saying and showing them? Are they scientists too? It sounds more like it’s going to be to a committee.” 

“They… are not scientists.” You saw the cold realization washed over him. They’d have no idea what he was talking about and the way he looked at you nearly made you feel guilty. All that work and they’d never understand it. Christ, that was brutal. It nearly made you feel bad for not getting it either. He was clearly onto something he desperately wanted to share, but it was like he couldn't simplify his ideas enough to explain what they were to anyone with a room temperature IQ.

You bounced your leg trying to think up a solution even though you still weren’t entirely sure why you gave a shit. You should just get up and go home. Tell him it’s late and you have to get some sleep. But no, you sat there puzzling trying to help this total stranger. You stood up, unable to sit anymore. The digging drive to pace while you thought winning out as it usually did so back and forth in front of the despondent scientist you went. “Ok, we can figure this out.” You assured, sounding more confident then you actually were. “You’re smart. I’m…well, I’m smart too. Just… not as smart.” You laughed, but he looked like a kicked puppy. Maybe you were the only smart one right now. 

You told yourself that was fine while you gnawed on your thumb nail. Chipping the black fingernail polish off with your front teeth. You were so tired. Your eyes hurt, your back hurt, your legs hurt, and you smelled like a sweaty ashtray full of cheap beer. You weren’t getting anywhere with this tonight. “When are you giving your presentation?” “Next week. Tuesday of next week.” It was only Monday, well, Tuesday now. You had time. 

“I’ll tell you what,” You turned to him with a clap of your hands that made him jolt to attention. “We’ll keep working on this. We’ll figure this out, but not tonight. I have to work today, but after that I’m free until Friday. Meet me here after work and I'll give you your money’s worth.” You winked at him “I owe you for what you paid me for, don’t worry. You still have,” after checking your watch you confirmed “Two hours and forty five minutes.” 

Jervis stood up, only coming up to the very bottom of your ribs “You promise?!” What a pathetically endearing man. “Promise.” You presented your pinky finger and he gasped like you’d presented you with a diamond ring, but he puffed himself up and raised his own pinky to interlock with yours. “Pinky promise, Dr. Tetch.” “I-I- Hehehe-” He wriggled like a worm on a hook. Turning red as the perfect shade of lipstick making the pale dusting of freckles over his nose and cheeks stand out. “I’ve never- ah… No one’s ever pinky promised me anything. Jolly good.” 

You couldn’t help, but snort. With a shake of your hands the pact was made.

[neuthanasia]

the immune system but they are weird and unusual marine animals that swim through blood

size here along with Den without the shadow thing ↓

Macrophage is 30m in length

Dendritic cell's full body is also 30m length (he is 6.09 in diameter in front)

Helper T and Neutrophil are both around 2.45m in length

B cell is 2m in length

NK cell is 3m in length

Monocyte is 4.3m in length

The Complement system would usually be around >2 inches

oh yeah,Den without the shadow thing

feel free to consider these fella's as my immune system's cell form

DC's appearance is inspired by _crim_reaper on twitter!

[foolishfoolsgold]

Fuck it. Official CaW car headcanon post

Red blood cells: Anything at all as long as it’s red and not too big (I’m looking at you, Honda Accord). They have a pizza-guy thingy on top shaped like a real RBC with a light inside that goes on when they’re oxygenated. Instead of decals they just have that and like a little Lyft driver sticker on the dash. Also all cells have their “names” (codes) on the back license plates. Often times the drivers will personalize their cars like crazy with bumper stickers and dashboard plushies and shit

Neutrophils: white Ford explorers (any year) all decked out w/ identifying decals and gear like cop cars. All immune cells have sirens btw

Killer Ts: Black Chevy Tahoeesssss, 2021 or newer. Have minimal decals but a front ornamental plate that says KILL like their hats

Eosinophils: any modestly sized pickups really, but Toyotas are a favorite. Usually pink with some kind of camo thing going on

B cells: this one’s probably my favorite. Subaru Bajas with giant antibody machine guns bolted to the bed. And Memory rides shotgun

Macrophages: gigantic Ford F-250s because yes. What if they were like super pale pink with a pearly finish and crazy spikes on the front bumper

Regulatory Ts: Shiny new Lexus RXs for powerful rich lady vibes. And also because this rosy bronze color specifically is just so beautiful I’ve seen it IRL a few times

Dendritic cells: SEMI TRUCKS!!!! A. Real dendritic cells are huge in general and B. they gotta carry all them antigens

[bpod-bpod]

Anti-cancer Courier

A virus-like particle engineered to deliver cancer-specific antigens [molecule, complex or fragment with potential trigger an immune response] to dendritic cells of the immune system which will in turn activate an attack by T cells on the tumour

Read the published research article here

Image from work by Ruijing Tang and colleagues

The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou, China

Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)

Published in eLife (reviewed preprint), June 2024

You can also follow BPoD on Instagram, Twitter and Facebook

[heckthis-heckallofthis]

Random headcanons I think of sometimes (Oops! All Friends spinoff)

Dendritic cell doesn't get his cytokine material himself, he employs the M cells in the bars to capture the most horrendous images of immune cells while they're all intoxicated (he wears a feather boa when he's activated <3)

Canon but I don't think a lot of people know, he has good voice acting skills with his singing + narration being pretty good

Leaves his plushies everywhere. Gave one to M cell to see if it'd cheer him up, it did because M cell was happy he tried helping him. Dendritic cell thought it was just because of the cuteness and purity of the lactic acid bacterium

He visits M cell so much, every time M cell rings up the dendritic cells for antigen presentation it's always our beloved Dendritick cell that comes to his bar to get it

Dendritic cell also started out absolutely terrified of bacteria, had to practice very hard with antigen presentation

There is written fiction of the neutrophils, probably a lot of BL let's be real

There is a popular book that is like Twilight but with those weirdos

All neutrophils except for 2145 have colored hair and eyes, I will not elaborate

More of a general thing rather than only friends, but neutrophils definitely have sharper teeth compared to non phagocyte cells

2145 goes to work everyday even on his off days, it's for a free lunch

2145 eats the body of cells right in front of other cells without thinking of the implications, he is enjoying the snack.

His favorite past time is listening to 1235 talk about her day, she is like a radio for him

3033 doesn't have a single creative bone in his body, you ask him to draw something and it barely even looks like what you wanted. He wears all white all the time because he doesn't know what outfits look good with what color, it's terrible.

Squad Leader would kill himself if he knew, but 3033 dislikes him. It's not for any particular reason, they just don't mesh well. It's okay since Squad Leader doesn't bother 3033 a lot anyways

Canon but I never realized this in 3 years of reading this manga: 3033 doesn't wear his knife straps on his legs if it isn't necessary to use those knives, only wears them when he needs to fight something dangerous.

M cell low-key has trouble eating enough because of his depression. You can directly counter this by getting him foods that expire within a day or two, he hates wasting food so he eats it before it expires.

Actually canon again but I need more people to know: M cell can make balloon animals

The fact that M cell has a lot of random skills in general, I wouldn't he surprised if he knew how to make stained glass art or could do wood carving

Cross reads the smuttiest, most vile BL stories as a past time. If you find his stash he will go insane.

He also enjoys talking to 1235 about squad leader (and then later on about 3033, girl talk)

1235 befriends so many immune cells because just like AE3803 from Main, she is a danger magnet. Everytime she is saved from an immune cell she makes small talk with them no matter how introverted they are (see 2145, NK and Eosinophil)

Helper T cell doesn't remember anything from his thymus days because it was so traumatizing he just blocks out those memories. It's not that he doesn't recognize Squad Leader, it's that his mind won't let him remember.

Squad Leader physically cannot hit another cell without orders, he can hit HT because Squad Leader is filled with so much rage every time he sees HT he just gains the strength to do it.

Also a general HC but I think Reg T cells in general have major face blindness. Unless you're someone close to them they will not recognize you once you do a change of clothes, but it's okay, as long as you still have the right receptors for the body they will protect you.

Eosinophil regularly visits M cell's bar because not only is it good practice for her with minimal casualties (poor M cell) but also it's an unpopular bar so she doesn't need to be so anxious.

B cell tried to hit on Eosinophil exactly once (1) and stopped because she exploded from anxiety and B cell thought she hated him so much she'd rather explode than talk to him

B cell and M cell don't like each other a lot, M cell thinks he's too loud, and B cell thinks he's too much of a downer. Partly the reason why Memory cell visited his bar alone without B cell

If you put NK and Eosinophil in the same room alone, they would just not talk. No conversation between those two. NK thinks Eos is judging her but Eos thinks NK doesn't like her and doesn't want to talk to her.

B cell and Mast cell get along surprisingly well (ignore how in canon Mast cell says he'll never talk to him again if he insults his gacha game girlies again), B cell talks about the pretty cells he sees regularly on the job while Mast cell show him his anime girls. Mutual respect until B cell is like "Well I prefer girls you can actually touch in the real world" in which Mast cell will tell him to shut up

[immunedoodles]

A professional-looking professional antigen-presenting cell!

What are dendritic cells?

Dendritic cells are immune cells which display antigens on their surface to present these antigens to T cells. They do this through engulfing something such as a bacterium and breaking it down into lots of small parts. Then peptides (short proteins) are presented in specialised molecules on the surface of the dendritic cell.

Why are dendritic cells ‘professional’ antigen-presenting cells?

Almost all of our cells are able to present antigens, through displaying peptides from the proteins the cell is producing on the surface of the cell in specialised molecules. This allows the immune system to ‘look inside’ the cell to see whether it is producing any abnormal proteins - these may be due to mutated DNA or a viral infection. Professional antigen-presenting cells use slightly different molecules to present antigens and also provide an additional activating signal to T cells.