#helper t cell

[strawberoni]

older CaW art I forgot to post… (around 3 months ago 😭)

[scopnotes]

Dale is a Helper T cell who suffers from a lot of frustration and self-hatred.

He despises knowing he’s an ‘imperfect’ (labeled ‘defective’) white blood cell but what’s even worse to him is being surrounded by them (Tars, Phal, Fleur, etc).

He spent his whole life masking his struggles alone while his squad never really needed to do that. He ends up getting pretty rough with Tars to the point where a fight occurs between the two.

Fortunately, she, and the group, will help Dale on opening up about his feelings.

And here is Amig!

A Regulatory T cell who becomes Dale’s assistant and emotional support in his job. They’re basically very chill and kind to everyone.

[thestorybotsfanlol]

Cells in my house

[neuthanasia]

the immune system but they are weird and unusual marine animals that swim through blood

size here along with Den without the shadow thing ↓

Macrophage is 30m in length

Dendritic cell's full body is also 30m length (he is 6.09 in diameter in front)

Helper T and Neutrophil are both around 2.45m in length

B cell is 2m in length

NK cell is 3m in length

Monocyte is 4.3m in length

The Complement system would usually be around >2 inches

oh yeah,Den without the shadow thing

feel free to consider these fella's as my immune system's cell form

DC's appearance is inspired by _crim_reaper on twitter!

[foolishfoolsgold]

Immune system go brr

A few designs I’ve done since I had this mutated brainchild back in October. I have others like eosinophil and dendritic but I wanna redraw them. I was still learning the way of the cell creature back then lol. Image IDs under the cut

[Start ID: The first image shows the AU design for U-1146. The background is white with a gray triangle pattern. He’s wearing his usual uniform, but he has a rounded, noseless snout, long ears without holes, and his one eye that is showing has black sclera and a round silver iris. His skin, turned cell membrane, is pure white with faint gray striped that resemble the markings of a raccoon. He has a tail with the same colors, it’s long, skinny, and has multiple lobes on it. Who on the very end, and a few dorsal lobes along its length. Again, like a raccoon, the tail has those faint stripes on it. He’s standing and staring at the viewer with his one visible eye, with his left hand in a fist, and the other gripping a silver knife. There’s some text next to his head that reads: “Only has one eye, and it can’t un-dilate so he always has that big sauger pupil we see in the media.” Another text box reads “Some raccoon inspiration because the official art makes it look like he has an eye mask.” There’s a piece of this official art in the top left corner of the image for comparison, and in the bottom right, there’s my watermark.

The second image shows Killer T Cell’s design. The background has an orange-yellow triangle design. He’s standing with his usual uniform, head turned and arms crossed. He doesn’t have bones, though, so his arms look more like they’re tied in a knot. He keeps his canon skin tone and hair style, but his membrane has dark blue markings that make him resemble a peregrine falcon. He shares the basic physical features with U-1146, except his tail is thinner and only has two small lobes on the end. His tail is yellow, like his hair, and has an arrow pointing from it to a picture of a banana flavored Snack Pack pudding package, noting that his tail looks a lot like banana pudding by humorously noting “Is it worth it?” Unlike 46, T’s hazel eyes are made up of multiple pupils that coalesce like a lava lamp, and this is true for all future entries as well. Again, there’s my watermark and an actual picture of killer t for reference.

The third image shows Macrophage’s design, and a cream-colored triangle background. Macrophage has large, frilled ears, and a darker cell membrane that looks almost like light coffee. She’s wearing her normal ruffled dress, but instead of legs, she has long tentacles without suckers, built almost like Ursula. She’s covered in white patterns with ripple-like stripes and spots, resembling a cuttlefish. With her right arm and one of her tentacles, she’s holding her signature cleaver, dripping with red blood, which also stained another tentacle and parts of her dress, and the other arm is held up to her face in an “I didn’t do that!” pose. She’s accompanied by a picture of anime Macrophage and a microscope photo of a real macrophage, reaching out with its “arms” to some bacteria. There’s a text box under it that reads: “like come on I HAD to make her a sea monster, have you seen real macrophages? Look at this bitch.” Another box reads: “lots of cephalopod inspiration, octopus-like build with cuttlefish markings and frills.” A final humorous box says “it’s ok she just had to refill the ketchup at McDonald’s,” referring to the blood.

The fourth image featured NK’s design with a green patterned background, as are the following images. She keeps her skin tone and clothes for the most part, but she has a centaur-like build. Her black tank top is extended to cover her chest and has short sleeves for her first set of legs, and ends with a belt around her midsection to her green shorts. She has green boots on all four of her feet, and her tail is black with green splotches, and has lots of lobes, almost like that of a leafy sea dragon. She has army-green spots resembling a cheetah, and she’s smiling and looking confident, with her left hand in a fist. She has her saber in a sheath on her back, and a brown bag secured to her belt like a saddlebag. There’s an arrow pointing to the photo of anime NK from a text box that says “there is something about this SPECIFIC png of NK that cracks me up sm and I don’t fucking know what it is.”

The fifth image shows Helper T, who shares many basic traits with Killer T such as bipedalism and a two-loved tail. While he still has the creature features like the big ears and rounded snout, he’s race-swapped as a black man, and has dark stripes along his arms and face like a peacock. His eyes are blue, and he’s holding a cup of green tea, dropping a cookie in it. There’s a small figure showing that his hair (flagella) are each coiled rather than straight.

The final image shows B cell’s design, which has a lot of bird inspiration. He has a longer snout, plumed tail and ears, and big flat lobes along his arms that look like wings. His eyes are silver md his stripes are brown and green, patterned like that of a blue jay. He’s also holding his antibody gun. A text box reads: “Bird boy! B cells were first discovered in birds and are named after the bursa of fabrics, a thymus-like organ for B cells that only birds have.” There’s also a note that says “face shape inspired by the Hilda bird because look at him,” accompanied by a screenshot of the raven from the Netflix series Hilda. He has a simple, completely black design with a rounded face, stick-figure legs and small wings. End ID.]

[ieatcerealboxes]

[macrophage-nursery]

Human AU names for the cells :

U1146 : Shirogane

U-4989 : Yashiro

U-2626 : Toshiro

U2048 : Kenshiro

U2001 : Mashiro

AE3803 : Akari

AA5100 : Akane

Killer T : Kenta

NK cell : Nikki

Macrophage : Maria

Helper T : Hiroto

Regulatory T : Reina (the name with R and T in the middle didn't please me so I half assed it haha)

B cell : Banri

Platelet : Hinako (it was hard to find anything cute with a P so I gave up and found a cute name instead)

Eosinophil : Koizumi (name starting with ko because : Kōsankyū

Basophil : Kohei (another name starting by ko because : Kōenkikyū)

Mast cell : Masumi (because Masuto saibou)

Dendritic cell : Juichi (because Jujo saibou)

Basic cell/Cell boy : Nobu

Cancer cell : Haneki (referring to the moment he had wings)

It's pure amateurish. Do you have your own version? If so, I'd be glad to see it!

[penguinofficer]

Haven't posted on Tumblr for a... While...

Just look at Helper T in the first photo, she looks like a proud momma!

[melangox]

Some sad cells at work hcs bc I’m bored

2048 has an eating disorder where he makes himself go days without anything expect water and or protein shakes due to him wanting to look perfect since in his past he used to be fat

4989 acts childish because he knows one day he’ll need to be put out commission and that day is coming soon enough

AE3083 kind of hates herself for being a sickle cell ( just my theory btw)

killer t picks on u1146 because he’s able to get along with other cells so easily

Memory cell has panic attacks due to his poor memory and thinking the end of the body is coming

NK cell will belittle herself for not being strong enough against a virus and or a forgiven substance that has entered the body

helper T cell has insomnia, he also wishes he was born as another cell instead of rotting away at his computer desk

memory is in an almost everyday mental anguish

That’s all, goodnight 🌙 <3

[makerofmadness]

so cells at work am I right

(I'm sorry)

[katsettee]

Studying for my biology finals by associating everything with how I think it would apply to Shadow the Hedgehog

[strawberoni]

Healthy lymphocytes be like… ✨

(I am a helper t x killer t truther <3)

[scopnotes]

Introducing Dale, a Lymphocyte T Helper.

He’s the second main antagonist of Unimune.

His role is to lead white blood cells and transmit informations to other lymphocytes about the enemy they’re fighting. He’s very serious in his role… maybe too serious…

[thestorybotsfanlol]

Kurzgesagt cells i made recently

[neuthanasia]

bored

on their duty

kinda wanna delete my recent post prior to this because it seems out of my usual content

[science-sculpt]

The T Cell Landscape

T cells, a critical component of the adaptive immune system, stand as the body's elite force in combatting infections and diseases. These specialized lymphocytes boast remarkable diversity, each type playing a distinct role in orchestrating a targeted and effective immune response.

T cells, like all blood cells, originate from hematopoietic stem cells residing in the bone marrow. However, their training ground lies within the thymus, a specialized organ located in the chest. Here, they undergo a rigorous selection process known as thymocyte education. During this process, immature T cells, called thymocytes, are presented with self-antigens (molecules unique to the body) by special cells. Thymocytes that bind too strongly to these self-antigens are eliminated, preventing them from attacking healthy tissues later. Only thymocytes that demonstrate the ability to recognize foreign invaders while exhibiting tolerance to self are released into the bloodstream as mature T cells.

Following this rigorous training, mature T cells exit the thymus and embark on their patrol, circulating throughout the bloodstream and lymphatic system. They remain vigilant, constantly scanning for their specific targets – antigens. Antigens are foreign molecules, such as fragments of viruses, bacteria, or even cancerous cells, that trigger the immune response.

The hallmark of a T cell is its T cell receptor (TCR), a highly specialized protein complex embedded on its surface. This receptor acts like a lock, uniquely shaped to fit a specific antigen, the "key." Each T cell develops a unique TCR capable of recognizing only a single antigen, enabling a highly specific immune response.

But how do T cells encounter these hidden antigens lurking within infected or cancerous cells? This critical role is played by antigen-presenting cells (APCs). APCs, such as macrophages and dendritic cells, engulf pathogens or abnormal cells, break them down into smaller fragments (peptides), and present them on their surface complexed with major histocompatibility complex (MHC) molecules. MHC molecules act as identification tags, allowing T cells to distinguish between "self" and "non-self." When a T cell's TCR encounters its specific antigen bound to an MHC molecule on an APC, a dance of activation begins. The T cell becomes stimulated, and a cascade of signaling events is triggered. This leads to the T cell's proliferation, producing an army of clones specifically tailored to combat the recognized threat.

T cells are not a single, monolithic entity. They comprise a diverse population, each type with a specialized function:

Helper T Cells (Th Cells):

Helper T cells, often abbreviated as Th cells, play a central role in coordinating immune responses. They express the CD4 surface marker and can recognize antigens presented by major histocompatibility complex class II (MHC-II) molecules. Subtypes of helper T cells include Th1, Th2, Th17, and regulatory T cells (Tregs), each with distinct functions and cytokine profiles.

Th1 cells mediate cellular immunity by activating macrophages and cytotoxic T cells, crucial for defense against intracellular pathogens.

Th2 cells are involved in humoral immunity, promoting B cell activation and antibody production, thus aiding in defense against extracellular parasites.

Th17 cells contribute to the immune response against extracellular bacteria and fungi, producing pro-inflammatory cytokines. Regulatory T cells (Tregs) maintain immune tolerance and prevent autoimmunity by suppressing excessive immune responses.

Cytotoxic T Cells (Tc Cells):

Cytotoxic T cells, also known as Tc cells or CD8+ T cells, are effector cells responsible for directly killing infected or aberrant cells. They recognize antigens presented by MHC class I molecules on the surface of target cells. Upon activation, cytotoxic T cells release perforin and granzymes, inducing apoptosis in target cells and eliminating the threat.

Memory T Cells:

Memory T cells are a long-lived subset of T cells that persist after the clearance of an infection. They provide rapid and enhanced immune responses upon re-exposure to the same antigen, conferring immunological memory. Memory T cells can be either central memory T cells (TCM), residing in lymphoid organs, or effector memory T cells (TEM), circulating in peripheral tissues.

γδ T Cells:

Unlike conventional αβ T cells, γδ T cells express a distinct T cell receptor (TCR) composed of γ and δ chains. They recognize non-peptide antigens, such as lipids and metabolites, and are involved in immune surveillance at epithelial barriers and responses to stress signals.

Beyond the Battlefield: The Expanding Roles of T Cells: The remarkable capabilities of T cells have opened doors for several groundbreaking applications in medicine:

Vaccines: By presenting weakened or inactivated forms of pathogens, vaccines "train" the immune system to generate memory T cells. This prepares the body to recognize and rapidly eliminate the real pathogen upon future exposure, preventing disease.

Cancer immunotherapy: CAR T-cell therapy, a revolutionary approach, genetically engineers a patient's own T cells to express chimeric antigen receptors (CARs) that recognize and target specific cancer cells. These "supercharged" T cells are then reintroduced into the patient, unleashing a potent attack against the tumor.

Autoimmune disease treatment: Researchers are exploring ways to manipulate T cells to suppress harmful immune responses that underlie autoimmune diseases like rheumatoid arthritis and multiple sclerosis.

The diverse array of T cells underscores the immune system's complexity and adaptability in mounting tailored responses against a myriad of threats. From orchestrating immune reactions to maintaining tolerance and establishing long-term immunity, T cells play multifaceted roles in safeguarding the body's health. Understanding the intricacies of T cell biology not only sheds light on immune-mediated diseases but also paves the way for developing novel therapeutic strategies harnessing the power of the immune system.

T cells represent a fascinating aspect of immunology, with their diversity and specificity driving the complexity of immune responses. As research advances, further insights into T cell biology promise to revolutionize immunotherapy and enhance our ability to combat diseases ranging from infections to cancer. By understanding and harnessing their power, we can unlock new avenues for protecting and improving human health.