#regulatory T cell

[moved-blogs13]

older CaW art I forgot to post… (around 3 months ago 😭)

[scopnotes]

Dale is a Helper T cell who suffers from a lot of frustration and self-hatred.

He despises knowing he’s an ‘imperfect’ (labeled ‘defective’) white blood cell but what’s even worse to him is being surrounded by them (Tars, Phal, Fleur, etc).

He spent his whole life masking his struggles alone while his squad never really needed to do that. He ends up getting pretty rough with Tars to the point where a fight occurs between the two.

Fortunately, she, and the group, will help Dale on opening up about his feelings.

And here is Amig!

A Regulatory T cell who becomes Dale’s assistant and emotional support in his job. They’re basically very chill and kind to everyone.

[ieatcerealboxes]

U-1146: what the fuck why are you helping out cancer cell

Regulatory t cell: that's oomf😭😭😭😭😭😭😭😭😭😭😭😭😭😭😭😭😭😭😭😭😭😭😭😭😭😭😭😭😭😭😭😭😭😭😭

[macrophage-nursery]

Human AU names for the cells :

U1146 : Shirogane

U-4989 : Yashiro

U-2626 : Toshiro

U2048 : Kenshiro

U2001 : Mashiro

AE3803 : Akari

AA5100 : Akane

Killer T : Kenta

NK cell : Nikki

Macrophage : Maria

Helper T : Hiroto

Regulatory T : Reina (the name with R and T in the middle didn't please me so I half assed it haha)

B cell : Banri

Platelet : Hinako (it was hard to find anything cute with a P so I gave up and found a cute name instead)

Eosinophil : Koizumi (name starting with ko because : Kōsankyū

Basophil : Kohei (another name starting by ko because : Kōenkikyū)

Mast cell : Masumi (because Masuto saibou)

Dendritic cell : Juichi (because Jujo saibou)

Basic cell/Cell boy : Nobu

Cancer cell : Haneki (referring to the moment he had wings)

It's pure amateurish. Do you have your own version? If so, I'd be glad to see it!

[humancelltournament]

Propaganda!

The regulatory T cells (Tregs), formerly known as suppressor T cells, are a subpopulation of T cells that modulate the immune system, maintain tolerance to self-antigens, and prevent autoimmune disease.

A phagosome is a vesicle formed around a particle engulfed by a phagocyte via phagocytosis. Phagosome formation is crucial for tissue homeostasis and both innate and adaptive host defense against pathogens.

[laqueus]

I got my ears pierced yesterday!

[darkmaga-returns]

The team conducted a major study to investigate surges in rapidly spreading and highly aggressive cancers among people who received Covid mRNA vaccines.

Some of America’s top oncologists have dubbed this phenomenon “turbo cancer.”

The study found that the prognosis in cancer patients worsened after each dose of the “vaccine.”

Notably, they found dramatically worsened prognoses in patients with pancreatic cancer (PC).

The results of the study were published in the journal PrePrints.

The study assessed clinical outcomes and immune markers in 272 patients diagnosed between 2018 and 2023.

The investigators report that patients who received three or more doses of mRNA vaccines exhibited significantly shorter overall survival.

Disturbingly, the researchers found that the average survival period halved among those who received Covid “vaccines.”

The average survival period following a pancreatic cancer diagnosis plummeted to 10.3 months among vaccinated patients compared to 20.8 months for unvaccinated.

The finding confirms that “vaccinated” patients’ survival time was reduced by over 50%.

The researchers also note that pancreatic cancer survival outcomes deteriorated significantly after 2021, coinciding with the Covid “booster” rollout.

Among the “vaccinated,” the study found elevated serum IgG4 levels and increased infiltration of Foxp3-positive regulatory T cells (Tregs) in tumor tissue.

The researchers explain that this immunological profile is suggestive of suppressed anti-tumor immunity.

[tzifron]

Here, I will give you, the reader, clear enumerations where SARS Cov 2 is unlike a common cold.

SARS Cov 2 triggers a unique, long-lived inflammatory overreaction unseen in Sepsis and influenza.

SARS Cov 2 sends T cells into the brain while lethal influenza does not.

SARS Cov 2 directly causes autoimmunity by reprogramming a special type of T cell called the T regulatory cell, which has never been observed before.

The human genetic line has not propagated any sarbecovirus elements therefore never has faced Sarbecovirus infection to the extent to evolutionarily adapt, except in the unlikely theoretical possibility of extremely negative selection (meaning infected humans did not create progeny.)

There are more exceptional facets but these are simple and digestible. There is also more to write about but I must make a confession. The status quo has morphed in such a way as to browbeat scientists into disavowing a harsh reality in order to acquiesce to corporate and business interests. As we see the average life expectancy decline, we have been left intellectually out in the cold. The truth tellers have been assaulted and crushed, and the individuals that comprise the public, in denial, will put off the realization of a below 70s life expectancy until each one approaches retirement in piecemeal, just as all the grains of sand in an hourglass do not fall at once.

[quitealotofsodapop]

Ok but what sort of side effect does Wukong deal with when it comes to making stone eggs? Because if the usual procedure would result in a Stone Monkey's death and damage to their very soul, then there has to be long lasting effects. Is Wukong just... permanently weaker and doesn't have as much endurance as he used to? Does he have moments of chronic illness and pain? Does he lose his breath easy or have lung and/or heart problems? What does the recovery look like for Wukong?

Permanent power debuff during and even after the Stone Egg pregnancy. In addition to a lot of typical pregnancy symptoms... for the next few centuries.

So much energy is needed just to form the egg, that having the parent "awakened" and surviving the process puts a *Huge* biological pressure on the body.

Wukong experiences a much weaker immune response than normal - his divine body and immortalities no match for regulatory T-cells keeping his immune system dampened to protect the Egg and/or to reduce post-partum inflammation. First time he ever caught a cold on the Journey - he thought he was dying cus he'd never experienced that kind of illness before. Spent the rest of the Journey super sus of anything that could get him sick. Same in the modern day; huge advocate for vaccines and mask-wearing. He wont die of illness, but he'll feel like it.

Chronic pain in his lower back and abdomen for like ever. Wukong's body argues with him after the baby arrives since it's been the same shape for hundreds of years, and it takes a while for him to stop having post-partum afterpains. Lots of heat packs, cold compresses, and massages from Macaque are needed to soothe this sore monkey.

Wukong also retains a bit more water afterwards (normal hormonal thing) so his ankles still swell up at odd times.

Gets short of breath a lot faster than he used to. Just something he has to deal with now.

Slightly gross but 100% normal post-partum symptom; Wukong is left with some issues making to the bathroom on time for the next few months or so. The Egg wrecked his "downstairs" on the way out.

Aesthetically; Wukong gets left with some gnarly stretch marks that are really hard for him to glamour off and it makes him a little self-conscious, but he's really proud of them esp since the marks are literally scars from surviving the Stone Egg pregnancy.

Most of the symptoms don't stack (thank buddha) when the lunar node twins happen, but Wukong does experience bonus morning/midnight sickness with them.

[foolishfoolsgold]

Love this animal. The T. Rex

[Start ID: colored and shaded digital drawing of Regulatory T Cell. She has her canon green suit and skirt, though the leggings are less yellow, or so-called “baby puke colored” now. Her membrane has light brown eyemask-like patterns, and her blonde hair/flagella are mostly canon as well, except her hair coils by her shoulders are twisted around each other like DNA strands. She also has plain shoes instead of high heels, and a discrete headset with an antenna by her left ear. She’s adjusting said headset with one arm, and her other is wrapped around an iPad. It’s noted that she has the same basic features as KTs and HTs, including pointed ears, a skinny tail with retractable stingers, brown markings, and the same quick-punch reflexes as KTs. Back to her stingers, the bigger one secretes purple perforin for apoptosis and the smaller one blue adenosine for temporary paralysis. In the bottom corner is a low-opacity meme of an enterocyte character with the sad SpongeBob face and Impact text that says “me when my wife gets arrested (she is a criminal and completely deserves it) and a watermark in the other corner. There is also a reference of RT’s canon design and notes about how “I do love the rest of her outfit fit though. We Stan green here.”End ID.]

[moved-blogs13]

(repost, sorry ahaha)

regulatory t and nk (≧∀≦)

me pairing the baddest btches together because it just makes sense yk… but in all honesty i love them both and their interactions have so much potential I LOVE THE BOTH OF THEM SM… i would make more art of them if i wasn’t shy

CELL YURI 4 LIFE >:3

[cbcbiology]

NEW IMMUNE SYSTEM ANALOGY which fell out of my brain while teaching

You have two wheely bins for trash.

One bin is for trash that you generate in your house (MHC I). If drug paraphernalia is found in that bin (by a cytotoxic T cell), your house is going to get raided and destroyed.

The other bin is for trash that you picked up at the park (MHC II). If drug paraphernalia is found in that bin (by a helper T cell), you will be encouraged to continue cleaning up the park, and also more resources will be devoted to park cleanup.

There are also the regulatory T cells looking through your trash and saying "that's OK, those drugs are legal in this state. Relax, everyone."

[ieatcerealboxes]

T cells in a nutshell

[theredumbrellatheory]

regulatory T cell you STUPID CUNT

[humancelltournament]

Human Cell Tournament Round 2

Propaganda!

A chromosome is a package of DNA with part or all of the genetic material of an organism. In most chromosomes, the very long thin DNA fibers are coated with nucleosome-forming packaging proteins; in eukaryotic cells the most important of these proteins are the histones. These proteins, aided by chaperone proteins, bind to and condense the DNA molecule to maintain its integrity.[1][2] These chromosomes display a complex three-dimensional structure, which plays a significant role in transcriptional regulation.

The regulatory T cells (Tregs), formerly known as suppressor T cells, are a subpopulation of T cells that modulate the immune system, maintain tolerance to self-antigens, and prevent autoimmune disease. T regulatory cells are a component of the immune system that suppress immune responses of other cells. This is an important "self-check" built into the immune system to prevent excessive reactions. Mouse models have suggested that modulation of Treg cells can treat autoimmune disease and cancer and can facilitate organ transplantation and wound healing.

[bpod-bpod]

T for Tolerant

Single cell analyses and live-imaging in mouse gut reveals mechanisms underlying tolerance of the immune system's regulatory T cells to chronic bacterial infection and the intestinal niches where this takes place. Greater understanding of the disruption of tolerance which results in colitis

Read the published research article here

Still from video from work by Yisu Gu and Raquel Bartolomé-Casado, and colleagues

Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford and Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK

Video originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)

Published in Nature, April 2024

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