#alentis

[fancylionart]

The design sheet for the Outer Ring! A lot of the islands throughout the rings, I drew inspiration from icebergs, but the Outer Ring is probably where the iceberg references came in the most handy.

[impact-newswire]

Alentis Therapeutics, the CLDN1 company, is a clinical-stage biotech developing breakthrough treatments for CLDN1+ tumors and organ fibrosis.

[cha0s-boyy]

alenti for @netatori

[ID: a cartoony digital drawing of a strange spirit creature. it has a somewhat feline body with six legs, and its head, tail tip, shoulders, and legs all have spikes of scribbly fur or light beams coming from them. it is mostly an offwhite color, with a lime green circle in its head, and a pale yellow one in its tail tip. its eyes are scribbly and outlined in a pinky red. it is curled around the image, with its head and tail tip at the top, its back along the right side, and its six legs down the center. its tail tip is glowing. /end ID]

[sphinxdrawsstuff]

LARP Caravan - Diplomatic Relations

Caravan returned recently, after a couple of years of hiatus, so it was fun to brush off some LARPing skills~

Feat. Ardélion'cath of Lenali, a water theumite (elemental), who had to explain to some stuck-up aristocrat alenti (humanish) that baby theumites are not, in fact, "pets".

[wikipediadogdotnet]

revenge on @netatori’s oc alenti ^_* plus an alt

[viranas-trolls-ask]

-> HELLO THERE MY SWEET  ♡ALENTINES <-

-> It yours trurly and only  Mr.  ♡alentino!

-> Yes! this onle Mr.  ♡alentino the famous fashion designer right from the sweet sweet island! And now with the help of my wife im gonna talk and answer all your questions

-> See you all later my  ♡alenties

[inceptionauta]

Design is a discipline committed to the industry because it confronts the problems of production and the problems of consumption, based on the significance of the artistic object.

1910

The main expression in Portugal takes place with the Loiças das Caldas da Rainha which, at the encouragement of Rafael Bordalo Pinheiro, were defined by a naturalistic configuration, be it organic elements or contours.

The implementation of advertising companies brings together several graphic design and marketing professionals.

O panorama internacional:

Le Corbuser,

F.L.Wright

R. Bordalo Pinheiro

1920

The tendency to invest in imported products is unlikely, depriving a more artisanal design and production with few references to the title of designer.

Cassiano Branco designs the Eden Theater, a building of palatial symmetry, highlighted by its Art Decó composition and proportion - the main novelty of the century.

The validation of international design is manifested, essentially, by the integration of different materials in the same object, in the finalization of objects with the intention of preserving them - without compromising the aesthetic value - and the principles of ergonomics, applied to the materials or in the techniques of manufacturing that emerge.

Rulhman - marfim, ébano, imbutidos

Jean Dunand - lacados, potes, cobre

Simmer - lacados

Puiforcat - Serviços para Chá

1930

O grafismo em português continua: Fred Kradolfer, Carlos Botelho, José Rocha.

🇺🇲 Dorwin Teague : Radio Soarton Model 557

1940

1950

Household appliances are multiplying and in attempts to store, transport or collect, straight and perpendicular lines are adopted - notions of universality.

🇨🇵 Marc du Plantier :

C. Permand, J. Pouvré : Bibliotheque M.

🇮🇹 Carlo Molino : Arabesque

🇮🇹 Gio Conti : Superleggena

🇺🇲 C. Eames : Poltrona

1950 | 🇺🇲 George Nelson : Bubble Lamp

The manufacturing and assembly processes become easier and the modular system becomes a patent.

Casa Tunísia

🇨🇭 Corbusier : Cite Radiosa

In architecture, Oscar Niemeyer dominates concrete with form and participates in the design of the United Nations Headquarters.

1960

Designers assume versatility parameters, not only for objectivity, but to react to prices established by the real estate market.

1971 | 🇮🇹 Joe Colombo : Total Furnishing Unit

000 | 🇩🇰 Verner Panton : Living Tower

In the technological aspect, the small size of the hardware allowed the machine to be designed based on art rather than engineering, establishing the machine, in itself, as a decorative element displayed in accordance with its aesthetic and functional value.

1965 | 🇨🇵 François Arnal: Drinks

🇮🇹 Achille Castiglioni : RR126

This factor also stimulated a proposal based on portability.

0000 | 🇦🇹 Ettore Sottass: Valentine

1964 | M. Zanus, R. Sappi: Alg

Making everything usable and adaptable.

1962 | 🇮🇹 Achielle, Castiglioni: Candeiro Arco

1960 | 🇮🇹 Enzo Mari: Jarra Pago-Pago

🇮🇹 Gae Alenti : Pristello Lamp

🇮🇹 Joe Colombo : Boby 3

All of this was made possible by the availability of malleable materials.

1962 | 🇵🇹 Daciano Costa : Cadeira Cortez

1968 | 🇮🇹 P. Gatti, C. Paolinni, T. Teodoro : Sacco

0000 | Sofá Dinn

In Portugal, adapting to modern design is not immediate. The prevalence of decoration made with furniture and trinkets inherited from parents or grandparents predominated. The reserved economic system limited this membership to industrial corporations, where names such as: Daciano Costa emerged.

1962 | 🇵🇹 Senna da Silva : School Chair

1986 | 🇵🇹 Daciano Costa : Logos

1970

In order to organize, designers choose to save space, providing areas of the structure for storage. Aesthetic simplicity complements manufacturing simplicity in materials that are increasingly easier to clean and keep clean.

Color and patterns become the focus, distorting, for example, the notion of broad and fixed lighting; the designer stipulates a greater diversity of different and specific pieces, creating a greater option for locating them depending on what is desired.

The notion of interior environment becomes common sense and the functional incompability between objects - with different types of materials - also requires solutions.

1976 | 🇵🇹 Afonso Dias : Bases Cortiça

From a more creative perspective, the secondary decor components express greater extravagance, offering a greater supply and consequent option of aesthetic or personal value.

1970 | 🇫🇮 Tapio Winkala : Paper Bag

1980

Italy emerges as the prominent influence on aesthetics and privilege, disseminated by Alchimia, founded by Alessandro Mandini in 1976.

Or Archizoom with Paolo Reganello.

And the fundamental design concepts are questioned by an Italian cluster with the title “Memphis” - Milano [1981], which exposes a fun perception of demonstrating design products, which includes the remarkable Ettore Sotass, Marco Zanini, Peter Shire, Andrea Branzi and Aldo Cibic.

19 | Gaelano Peace: Sunset in NY

0000 | Toshyuki Kita

The Portuguese industrial sector is attentive to quality, motivated by the greatest supply, resulting from technological modernization that aims to commercial activity internationally.

1985 | 🇵🇹 Tomás Taveira: Rick Chair

1985 | 🇵🇹 Tomás Taveira: C. C. Amoreiras

1990

The designer approaches a practice of ecological sustainability, presenting several pieces with less processed and less synthetic materials, committed to reuse and the indispensable, as a patented and enlightening solution for the consumer.

Tejo Rémy | I can't let go of your memory

Roby Graumans | 85 lamps

Frank Gehry | Cross-check

Andrien Gardére | Stainless Steel Tank

0000 | Martin Szekely: Stragno

The material property is again investigated for the ambition to provide organic and aerodynamic aesthetics. 

1997 | Frank Gehry: Guggenheim Museum 

0000 | Marc Newson: Orgone Stretching

The challenge of creating, stimulated by the industry, the contract, the meeting and the accreditation of the brand or company enhanced the designer's professional practice, validating it until today. 

1996 | Dyson: Vacuum Cleaner

0000 | Alfa Romeo: 156

0000 | Frog Design :

000 | IDEO

2000

2010

2020

Matter; reecofee

[444namesplus]

A Abe Abi Abia Abian Abie Abienn Abin Abith Abl Ablit Abrer Abric Abrici Abrie Abriel Abrin Ac Acaren Acdonal Achae Acharyabbot Ache Achec Acia Acint Acitu Acki Ackso Acksonvill Aco Acob Acobso Acque Acquelin Acquely Acrament Acrinu Acund Ad Adde Addo Ade Adelein Adelin Adi Adill Adin Adisla Adislau Adiso Adria Adriqu Aell Aeta Aetiti Afae Afael Afayett Ag Agal Agdalen Aggi Agma Agne Agnu Agober Ah Aile Aim Aimund Aine Aintpau Air Airfiel Ais Ait Ajoria Ake Akelan Akersfiel Akewoo Aklan Al Ala Alaza Alb Albinu Alde Aldero Aldonad Aldwel Aldwi Ale Aleig Alen Alenci Alenti Alentin Alentinia Alenzuel Aleri Aleria Aleriu Alhou Aligul Alil Alina Alixt Alke All Alla Allac Allaghe Allaha Allahasse Allar Alle Allego Allej Allienu Allowa Almba Almdal Alme Alomo Alon Alp Als Alt Alte Alter Altimor Altlakecit Alto Alvado Alvi Alvin Am Amach Amanth Amar Amas Amber Ambl Ambridg Ame Amel Amero Ami Amia Amie Amil Amill Amilto Amir Amire Amm Ammon Amo Amon Amor Amp Ampbel Ampo Ampso Ampto Amse Amue An Anagu Anantoni Anc Ancaste Anch Anche Ancheste Anchocucamong Ancoc Ancouve And Andac Andal Ande Ander Andic Andid Andieg Andolp Andova Andr Andrin Andyspring Ane Anes Aness Anfor Anfrancisc Angle Ani Anic Anie Aniel Aniell Anin Ank Anmate Ann Anna Anne Annelor Anni Annic Annin Anno Ano Ansascit Anse Ansin Anso Ant Antaan Antaclar Antaclarit Antamari Antan Antaros Antiag Anto Antrel Anue Anuel Anut Any Aom Apecora Apervill Aphae Aptist Aqu Aque Ar Ara Aracall Aral Arbar Arbe Arce Arcel Arcelin Arcell Arci Arcia Arcis Arco Arcu Ard Ardena Ardi Ardin Ardne Are Ared Arg Arga Argare Argaret Argarit Argen Argi Arguerit Ari Aria Arian Ariann Aribe Arida Ariechristin Arieclaud Arietheres Arily Arin Arinu Ario Aritz Ariu Arjori Ark Arke Arl Arlan Arle Arlen Arlhein Arlo Arlot Arlsba Arlso Arme Armo Arne Arnet Aro Arol Arolin Aroly Arpe Arpente Arque Arr Arre Arrel Arrer Arret Arri Arrie Arrill Arringto Arris Arriso Arro Arrol Arrollto Arry Ars Arse Arsh Arshal Arso Arson Arste Art Arte Arth Arti Artin Artine Artlet Artma Arto Artolom Aru Arve Arvi Ary Aryan Arz As Asaden Asca Ascal Ascruce Ascua Ascual Ase Ash Ashingto Ashvill Asi Asili Asiliscu Asimir Asmin Asmusse Aso Asque Assandr Asse Astaned Astia Astill Astr Asvega At Ata Atali Atalin Atash Ate Ater Aterbur Aterso Atfiel Ath Atha Athali Athanie Athe Atherin Athew Athi Athie Athild Athlee Athry Ati Atia Atild Ativida Atj Atkin Atlif Ato Atonroug Atoy Atri Atric Atrici Atrin Ats Atso Att Atterso Atthe Atthew Atthia Atthie Atti Attl Atto Aty Au Aue Aufma Augh Augha Aughert Aul Aulett Aulin Aulit Aulkne Aunder Aur Aure Auree Auren Aurenc Auri Auric Av Avag Avarr Avenpor Avern Avi Avidso Avie Avier Aw Awkin Awrenc Awso Awye Axentiu Axim Aximia Aximilia Aximinu Axin Axte Axwel Ay Ayan Ayde Aye Ayetan Ayl Aylo Aymon Aymond Ayn Aynar Ayne Ayt Ayto Aze Azque

Bab Bigai Bilen Bon Braha Brie Bsalo Bundi

Calle Cbrid Ccal Ccart Ccarth Cclai Cclur Cco Cconnel Ccormic Ccra Cculloug Cdanie Cdonal Cdowel Cean Ceansid Ceved Cfadde Cfarlan Cge Cgowa Cguir Chede Chmid Chneide Cho Chroede Chult Chwart Cintos Cintyr Cka Cke Ckenzi Ckinne Cknigh Claughli Clea Cleo Cmaho Cmilla Cnei Conno Cost Cot Cottsdal Cpherso

D Da Dalbert Dam Ddi Del Delaid Delhei Deli Dett Dga Dgard Dil Diso Disod Dit Dkin Dmun Dmund Dn Do Dol Dolf Donnel Dria Drian Drienn Duard Dwar Dward Dwi

E Ea Eac Eadow Eagen Eanclaud Eandr Eanett Eanfrancoi Eanloui Eanlu Eanmar Eanmari Eanmiche Eann Eannett Eanni Eannin Eanpau Eanpierr Ear Earlan Earso Easle Eat Eathe Eatri Eatric Eattl Eaumon Eave Eb Ebastia Ebastie Ebbi Ebe Ebec Ebecc Ebeh Eber Ebhar Eblan Ebor Ebora Ebr Ebste Ec Eceli Eci Ecil Ecili Eck Ecke Ecto Ed Edar Ederic Edin Edr Edri Ee Eek Ees Eeve Ef Effer Efferso Effre Eg Ega Egg Egha Egi Egin Eginal Egon Egund Ei Eid Eidemari Eig Eill Ein Eine Einhar Einhol Einra Einric Eir Eis Eit Ejesu Eji El Elacru Elane Elani Elasque Elay Elazque Elb Elc Ele Elen Elende Eleo Elg Elgad Eli Elici Elician Elicida Elin Elind Elip Elis Eliss Ell Elle Eller Ellevu Elli Ellmut Elm Elmu Elmut Elod Elore Elphin Elso Elto Eltra Elvi Em Embrokepine Emecul Emedio Emp Emphi En Enar Enat End Ende Enderso Endoz Endr Endri Endrick Ene Enedik Enehar Enev Eneviev Eni Enis Enit Enjami Enkin Enn Enned Ennet Enni Ennife Enning Enningto Enoi Enr Enriett Ense Ensle Enso Entennia Entle Ento Entr Enve Enze Eo Eodor Eofil Eon Eonar Eonard Eono Eontio Eopold Eor Eorg Eorge Eorgett Eorgi Eori Eptimiu Er Eracliu Erafin Eraklona Eral Eraldin Erar Erber Ercad Erce Ercede Erdinan Ere Eredit Erem Eres Erg Erge Ergi Erguso Erhard Erkele Erkin Erma Ermain Erman Ermi Ermin Ern Erna Ernadett Ernand Ernande Ernar Ernard Ernardin Erne Ernhe Ernic Erno Ero Erom Eronic Eroniqu Erqu Err Erran Erranc Errand Errel Errenc Errer Erric Erril Errin Errit Erseycit Ersh Ersti Ert Erth Ertina Ertra Ertran Ertrud Erv Ervante Erwi Es Esa Esamparado Eseni Esire Esle Esli Espasia Esquit Ess Essi Essic Este Estjorda Estminste Estpalmbeac Estvalleycit Esu Et Ete Eter Eterse Eterso Ethan Etici Etrani Etroi Etroniu Ets Ett Etti Eula Ev Everi Everin Everl Everu Evi Evin Ewi Ewisvill Ewit Ewma Eworlean Ewportnew Ewto Ewyor Exingto Exto Eye Eyer Eynold

Feli Fre Fric

Gapit Gidi Gnaci Gne Gued Guila Guirr Gustin Guye

Ha Haffe Hamber Han Handle Hane Hanno Hanta Hapma Har Harle Harlen Harlesto Harli Harlott Haro Harp Has Hattanoog Have Haw Hawn Haxirax He Heele Heil Heli Hell Helle Helm Help Helse Helto Hem Heodor Heodosio Heodosiu Heophilo Hepar Hepher Heppar Her Heres Herma Herr Hery Hesapeak Heste Hiar Hicag Hield Hierr Hiladelphi Hili Hilip Hilipp Hilippiko Hilli Hillip Hirle Hislain Hit Hitake Hitehea Hitfiel Hitle Hitne Hlo Hoca Hode Hoeni Homa Hompso Hond Hor Hornto Hri Hrist Hriste Hristell Hristense Hristi Hristia Hristian Hristin Hristo Hristoph Hristophe Hulavist Hurc Hylli

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Kinne Kkehar Klahomacit Kro

La Lac Lackbur Lackwel Lady Lagabalu Lai Lain Lair Lak Lan Lanc Lanch Lanchar Lankenshi Lar Larenc Lark Larksvill Las Late Lath Lau Laud Laudi Laudin Laudiu Laus-pete Lavi Layto Lb Lban Lber Lbert Lbuquerqu Ld Le Leano Learwate Lei Lejandr Lemen Lemenc Lement Lemin Lemon Len Lend Lendal Letche Levelan Levin Lexande Lexandr Lexandri Lexi Lexio Lfons Lfor Lfre Lfred Lfried Lg Lgi Lia Lian Lic Lici Liffor Lifto Lin Linto Lis Lisabet Lise Liso Liv Live Livi Livie Lizabet Lk Lkgrov Ll Lla Lle Llentow Lli Lliot Lliso Lm Lma Lme Lmont Lmu Lmuden Lo Loa Lodi Loi Lois Lon Londr Lor Lore Loren Lorenc Lorenci Lori Loria Lotild Love Lovi Lower Loy Lric Lrik Ls Lse Lsi Lso Lsto Ltagraci Lvar Lvarad Lvare Lvi Lvir Lwi Lybriu Lyceriu Lyd Lyn Lyss

M Mah Mal Mali Mand Mandin Manue Marill May Mbe Meld Meli Merso Mi Mil Mili Mit Mm Mmanue Mmanuell Mmeric Mpar

N Na Nahei Nak Nap Nastasio Nastasiu Ncarnacio Nchorag Nd Ndependenc Nderso Nderwoo Ndianapoli Ndr Ndre Ndrea Ndrew Ndroniko Ne Nea Nei Neil Ng Nge Ngel Ngele Ngelic Ngelik Ngelin Ngeliqu Ngi Nglan Nglewoo Nglis Ngra Ngri Niba Nicet Nide Nig Nigh Nit Nk Nmaculad Nn Nnalies Nnarbo Nnelies Nnelis Nnemari Nnett Nni Nnic No Nowle Noxvill Nriqu Nriquet Nsga Ntari Nter Nthemiu Nthon Ntioc Nto Ntoin Ntoinett Ntoni Ntoniet Ntoninu Nyde Nz

O Oa Oac Oachi Oan Oann Oanne Oaqui Oaquin Ob Obb Obbi Obbin Ober Oberso Obert Obertso Obi Obia Obil Obinso Obl Oble Obur Oby Oc Ocelyn Och Ochell Ochra Oci Ockfor Od Odest Odg Odge Odger Odne Odolf Odrig Odrigue Odrique Odso Oe Oeaaro Oeli Oell Oem Oemi Of Offe Offma Ofi Oga Oge Ogeli Oger Oh Ohame Ohan Ohann Ohanne Ohe Ohn Ohnn Ohnni Ohnso Ohnsto Oi Ois Oise Oja Ol Ola Olan Oland Olang Olb Olcom Olde Ole Oled Oleda Olema Olett Olf Olfgan Olge Oli Olie Olin Oll Ollan Ollar Ollee Ollegestatio Ollie Ollin Ollowa Ollrat Ollywoo Olma Olme Olo Olomo Olore Olto Olumbi Olumbu Oma Omai Omano Omas Omb Ome Omer Oming Omingue Ominiqu Omitia Omm Ommodu Omon Ompanobeac Ompto Omulu On Ona Onal Onaldso Onatha Oncepcio Oncor One Ongbeac Oni Onic Onifaci Onik Oniqu Onj Onkersaaro Onle Onn Onne Onni Onolul Onoriu Onova Onra Onro Onsolacio Onstan Onstanc Onstantin Onstantiu Onsuel Ontgomer Ontoy Ontrera Ontserra Onwa Ony Onzal Onzale Oo Ood Oodar Oodbridg Oodma Oodwar Oodwi Ook Ooke Ool Oole Oon Oone Oope Oor Oot Oote Oove Op Ope Opek Opelan Ophi Opkin Oppe Or Ora Orale Orali Oray Orbe Orda Ordia Ordo Ore Oree Orema Oren Orent Orenz Orett Orfol Org Orga Organ Orgelin Ori Orin Orinn Orit Orkma Orm Orma Orn Orneli Oron Orote Oroth Orpuschrist Orrain Orranc Orre Orri Orriso Orro Ors Orse Ortcollin Orte Ortensi Orthcharlesto Orthlasvega Ortlan Ortlauderdal Orto Ortwayn Ortwort Orwal Os Osale Osali Osangele Osari Ose Osef Osefin Osemar Osemari Osep Osephin Osett Oshu Osi Osin Osle Ostames Oste Ostilia Osto Osu Ot Otha Otso Ott Otte Ottfrie Ottlie Otto Ottschal Ouell Ougla Oui Ouis Oul Oulde Oun Oundroc Ourde Ourtne Ous Ousto Outhben Ov Ovadong Ovia Ow Owar Owe Owel Ower Owlan Owle Owma Own Owne Ownsen Oxan Oxann Oy Oyc Oye Oyl Oyne

Pa Park Pear Penc Pence Pri Pringfiel

R Ra Rac Race Racel Raciel Rad Radfor Radle Radsha Raf Raha Rai Raja Rak Rame Ran Ranc Rance Ranci Rancin Rancisc Rancoi Rancois Rand Rando Randprairi Randrapid Rang Rank Rankli Rantx Rat Ratia Rauk Rauli Rave Ravi Rawfor Razie Rcadiu Rdon Re Rebonianu Red Reddi Rederi Rederic Redri Ree Reema Reen Reenba Reensbor Regor Regori Remon Ren Renc Rend Rene Renna Resha Resn Resto Ret Retche Rete Revin Rewe Rhar Ri Ria Rian Ric Rici Rickso Rid Ridge Ridgepor Rie Riedeman Riedric Riffi Riffit Rigg Righ Rigitt Rik Rime Rinc Rinida Rio Risc Riscill Rist Rista Riste Risti Ristin Ristoba Rit Rittan Rland Rlen Rlett Rm Rmand Rmi Rmstron Rnau Rnd Rnes Rnest Rnestin Rnol Ro Robu Roc Roil Roila Roilan Rokenarro Rook Ros Rosb Rovidenc Row Rownin Rownsvill Rsul Rtabasdo Rteg Rthu Rti Rtru Rtur Ru Ruc Ruit Rujill Run Runild Rvad Rvin Rwi Ry Rya Ryan Ryst Rysta

S Saa Sabe Sabell Sbor Sborn Sca Scensio Shle Sidor Sidr Smae Speranz Spinoz Ssi Stanisla Ste Steba Stefani Stel Stell Sthe Strad Stri Suncio Swald

T Tac Tace Taffor Tahis Tamfor Tanle Tanto Tar Taurakio Teel Tefani Tei Tell Tephan Tephani Tephe Tephen Tephenso Tev Teve Teven Tevenso Tewar Th The Then Thma Tienn Tkin Tkinso Tlant Tockto Toke Ton Tou Tricklan Tron Tt Ttoma Tuar

U Ua Uadalup Uan Uanc Uanfra Uanit Uare Ub Ubbar Ubboc Ube Uber Uc Uca Uchana Uci Ucian Ucie Ucienn Ucill Uciu Ucke Ucket Uckle Uckne Ucso Ud Udit Udle Udolp Udovi Udre Udso Udwi Uebl Uelle Uente Uenti Uerr Uerrer Uf Ufemi Uff Uffal Uffma Ug Ugen Ugeni Ughe Uguett Ugus Ugust Ugusti Ugustu Ui Uid Uillaum Uillerm Uillermin Uin Uintillu Uis Uk Uka Ul Ulali Ulbert Ulc Uli Ulia Ulian Ulie Uliet Uliett Uliu Ulle Ullerto Ullin Ulliva Ulloc Ulm Uls Ulto Umbert Umeria Ummer Umming Umphre Un Unca Une Unic Unla Unningha Unnyval Uno Unte Unthe Untingtonbeac Untsvill Up Upienu Ur Ura Urban Urc Ureli Urelia Urelie Urfreesbor Urge Urges Urha Uri Uric Urie Urificacio Urill Urk Urle Urn Urne Urnet Uror Urph Urpris Urr Urra Urri Urriet Urs Urti Urto Us Usa Usan Usann Usi Uss Ussel Ust Ustav Usti Ustic Ustin Ustinia Ut Utchinso Uthri Utierre Utle Utledg Utol Utt Utto Uzann Uzma

V Va Van Vansvill Ve Vely Velyneachi Venj Ver Veret Verlandpar Vett Vetteaemilia Vil Vitu Vonn

W Wal Wanso Wayn We Wee Weene Wen Wendoly Wigh Win

Xe

Ya Yal Yat Yd Ydi Ye Yer Yke Yl Yla Yle Ylvai Ylveste Ylvi Yn Ync Ynd Ynett Ynn Ynthi Yon Yr Yracus Yri Yria Yro Yron Yrtl Yso

Zequie Zucen

[healthcarehubhh]

Growing Antibody-Drug Conjugates Market Owing to Rising Demand for Targeted Cancer Therapy.

Antibody-drug conjugates (ADCs) are a type of bioconjugate consisting of monoclonal antibodies that are attached by chemical linkers to highly potent anti-cancer payloads. ADCs selectively target antigens that are highly expressed on tumor cells while sparing normal tissues through the use of antibodies. Linkers attached between the antibody and cytotoxic drug allow for the drug to be delivered unchanged until it reaches the intended tumor site, minimizing harm to healthy cells. ADCs have demonstrated clinical efficacy in treating various cancers including lymphoid malignancies, breast cancer, and solid tumors.

The Global Antibody-Drug Conjugates Market is estimated to be valued at US$ 5.38 Bn in 2024 and is expected to exhibit a CAGR of 14% over the forecast period 2023 to 2030. Key Takeaways: Key players operating in the Antibody-Drug Conjugates are AstraZeneca PLC, Daiichi Sankyo Company, Limited, Novasep, ADC Therapeutics SA, Alentis Therapeutics AG, F. Hoffmann-La Roche, Gilead Sciences, Inc., AbbVie Inc., Biosion USA, Inc., Astellas Pharma Inc., Duality Biologics (Suzhou) Co. Ltd., BioNTech SE, LaNova Medicines Ltd., Bliss Biopharmaceutical, Eisai Co., Ltd., ProfoundBio, Pfizer, Inc., ImmunoGen Inc., Mersana Therapeutics Inc., Sorrento Therapeutics Inc., Oxford BioTherapeutics Ltd, and Takeda Pharmaceutical Company Ltd. Growing demand for targeted cancer therapy with minimal side effects is expected to drive significant growth of the ADC market over the forecast period. Additionally, ongoing technological advancements in linker chemistry, increasing pipeline products and approvals are further fueling the market growth. Market Trends: The ADC market is witnessing increasing adoption of cleavable linkers that are stable in circulation but rapidly release the drug payload intracellularly upon internalization into target tumor cells. Additionally, the development of novel conjugation technologies such as DBCO-azide click chemistry is allowing for site-specific conjugation without effect on bioactivity and efficacy of ADCs. Market Opportunities: The significant opportunities in the ADC market are in developing ADCs for liquid and solid tumor indications with unmet medical needs. Additionally, optimization of physiochemical properties of molecules to improve pharmacokinetics is another key area that ADC developers are increasingly focusing on to enhance therapeutic index and efficacy of ADCs.

[coulisses-onirisme]

Claude CAHUN Marcel MOORE (deux femmes en couple amoureux et actif)

Femme, féministe, hors genre, photographe, écrivaine, comédienne, artiste multiple, engagée politiquement contre les nazis, résistante active (19ème 20ème siècle)

Elle réalise, de 1949 à 1953 une série de photo intitulée Le chemin des chats18, à La Rocquaise, ou sur le Mur de l'Atlantique ou Atlantik Wahl construit par les allemands le long de la plage St Brelade, toujours visible (Ile de Jersey)

« Je sens comme si je les voyais, mes cuisses maigrir d'une sueur de fièvre, douche parfois brûlante, parfois glacée, toujours inattendue. Mes genoux vidés, les os dissous, vêtu d'un parchemin lucide, se gonflent, flottantes vessies de porc. Mon cœur alenti sonne un glas funèbre, puis bat bruyamment comme un tocsin. Il devient mobile, se promène dans mon ventre, y éclate en coliques profondes. À chaque secousse, une conscience tombe, pulvérisée. Peu à peu, je m'allège. Bref répit ! Mon cœur se gonfle outrageusement et s'emplit d'hydrogène. Gros ballon rouge et bleu, il monte au bout d'un fil. À l'autre bout, c'est une guêpe enfermée, qui frappe à coups venimeux aux parois de ma poitrine. Si je l'aidais à sortir ? Et mes ongles sans hésiter pratiqueraient un jour qui guide l'échappée de ce cœur s'il ne faisait dehors désespérément noir. Ô nocturne sans issue qui se joue dans les cercles de la nuit musicale, infernal serpent qui s'est décapité en avalant sa queue, bracelet aux sept chaînes hermétiques » Colville 1999, p. 56

Claude CAHUN Marcel MOORE (two women in a loving and active couple)

Woman, feminist, nogenrer, photographer, writer, actress, multiple artist, politically engaged against the Nazis, active resistance fighter (19th to 20th century)

From 1949 to 1953, she produced a series of photos entitled Le chemin des chats18, at La Rocquaise, or on the Atlantic Wall or Atlantik Wahl built by the Germans along St Brelade beach, still visible (Island of Jersey). )

“I feel as if I saw them, my thighs losing weight with a feverish sweat, a shower sometimes hot, sometimes freezing, always unexpected. My emptied knees, dissolved bones, clad in lucid parchment, swell, floating pig bladders. My slowed heart sounds a funeral toll, then beats loudly like a tocsin. It becomes mobile, wanders around in my stomach, bursts into deep colic. With each shock, a consciousness falls, pulverized. Little by little, I lighten up. Brief respite! My heart swells outrageously and fills with hydrogen. Big red and blue balloon, it goes up at the end of a thread.

At the other end, it's a trapped wasp, striking venomous blows at the walls of my chest. What if I helped him get out? And my nails without hesitation would practice one day which guides the escape of this heart if it were not desperately dark outside.

O nocturnal dead end which plays out in the circles of the musical night, infernal serpent which decapitated itself by swallowing its tail, bracelet with seven hermetic chains” Colville 1999, p. 56

Chemin des chats, 1948. Claude Cahun

[fancylionart]

The Outer Ring of Alentis is the thinnest habitable zone of the planet, as well as the highest altitude. As a result, the climate on the Outer Ring is uniformly cold throughout. The Outer Ring is as sparsely populated as the Core Islands. The atmosphere is thinner here, and the gravity weaker. Smaller islands, dust, and bits of frozen water float among the Outer Ring Islands, and occasionally escape the pull of the God of Gravity, floating out into space. The high amount of dust in the Outer Ring make dust storms a common hazard and can make travel between the islands more risky than it is on the lower zones.

[dixvinsblog]

Joëlle Petillot -La maison porte son cœur d’automne

La maison porte son cœur d’automne, alenti sous une pluie fine poudrant les fenêtres sans un bruit. Dehors un gris têtu arase le jardin de son absence de roux, de lumière, de nuance. Ne brillent plus qu’un reste de vert mouillé, un arbre malheureux, les fleurs orphelines.À l’étirement des heures on mesure combien la lenteur s’invite, jusque dans les odeurs. La saison se veut longue de parfums qui…

[444names]

greek islands + roman emperor forenames BUT excluding "s" and similar to "terrain"

Aeipata Agala Agania Agonia Agonidi Agoura Agria Aitia Albinti Alenti Aletani Aloula Alovali Ammolia Amvitia Amvitrac Amvolia Anari Andia Andiani Andianti Andra Andro Aneradi Anian Anthadio Antian Antino Antzo Arajanti Araki Ardia Ardili Areboe Arichada Arinia Armadia Aronera Aroniki Arontian Arpipana Atheoni Athiza Atikarda Augravia Augria Auria Avaleian Avati Avgoro Aviana Aviani Baleian Baloudia Caleian Calyce Caratheo Cardia Careia Carian Carna Carogia Cepho Cerina Chalucia Chilaza Chilo Cleian Commeza Comytha Congaio Conoi Conora Corgo Crepha Crevi Dakidi Diako Didia Didida Diomili Dokia Dokonian Dolian Dolyara Dolybri Domiko Domula Dophizou Dopoi Dorian Douda Doulafi Douraki Dracia Drakra Drian Driouda Drizoea Droggyli Drova Drovoni Elamara Elantiki Elavi Elaximin Elazafi Elekho Eletaba Elona Erianti Euberia Euboe Falexi Falia Falko Falona Falori Faria Fleri Fokiana Fokoleia Fonia Fonidi Forian Forina Forinera Fouda Frada Fraki Frako Gabalba Galene Galeo Galida Galki Galouri Gandia Gandou Gandroni Gania Gatela Gatro Gelaki Getelo Ginina Giouda Giropori Glantia Glyara Glyaria Glybri Glycepti Glymi Gracali Grataura Griamin Grian Gyala Gyarmaxi Gyarti Gylian Hadida Haeia Hemia Hemiteri Heopori Hergo Heria Houla Houra Hrian Hrovro Htera Hteria Htero Hydou Hymada Imada Imardia Imnora Iragoria Iragoula Iratolo Irina Ithili Itokia Johno Jorgo Joria Jovida Julaio Julaza Julida Julipera Kadia Kalaioi Kalega Kaleira Kalevia Kalia Kalianto Kallia Kalon Kalucia Kamotheo Kaneri Kangyli Kania Kantzoea Kardaki Karetala Karharo Kariman Karmajan Karnalki Karonia Kavdoni Kavia Kefala Kefaler Kefka Kefori Kelia Kepha Kephoni Keragala Keraki Keratina Keria Kerine Kinerina Kiniouda Kliki Kloki Kloni Konthnoi Kopaxi Kopla Koporia Kopoulo Korfu Korgo Korina Kouda Kougra Kouli Koura Kouraki Kratzo Krian Kroko Kyria Kyriania Kyrianne Kyrna Kythero Kythnoi Kytho Kyttauri Laforian Laian Larda Lavatan Lavra Lazafi Lazariza Legan Leianian Leiria Lekho Lekhoi Lekhoni Lendra Lentordi Leodonio Leopeti Lerakia Leramori Lerinan Levian Lexioi Liantin Madel Madia Madian Maididi Majoanne Makargo Makia Makidi Makiman Makini Makio Makoni Makra Makraki Makro Makyntia Manaro Mandra Manga Mantho Manti Maracla Maran Mardak Marepti Marga Margo Maria Marifno Markou Marlia Marlo Maroi Matikra Matzo Mauda Mauria Mavala Maxan Maximi Maximia Megala Megan Megana Megati Megia Michino Milio Minava Mothone Mouri Neira Nerian Oinia Olian Olmaroko Olmathio Olone Olonia Omauda Omfon Othizoe Othoula Oxentio Padelia Palexan Pallia Paloro Pantilo Papoi Pateraki Patha Pathari Patzo Paxandi Paximi Paximia Paximio Pelavi Pelli Pellou Peria Petakro Petan Petaura Petellio Petia Pettalli Phizou Phonti Phorgo Pidopla Pikolman Pinori Plokouda Poine Ponthemi Porfu Poria Poula Poulain Poulia Prago Pragra Praki Prati Profaro Progia Prouri Quina Reira Rhacreti Rhioura Rhireni Rhoni Roggyaia Romadak Romori Romvida Tandria Tanti Thaemno Thalian Tharan Themili Theona Theria Therinan Thilli Thilogia Thira Thoinadi Thoni Tibela Tikolia Tikyro Tilia Tintian Tippio Trela Triapaxi Tromadia Tronida Valba Valli Vallouli Valora Valymno Vathio Vathoi Vatian Vatikoi Vatikou Vouti Vrakida Vramoula Vroni Zarlouda Zendi Zentia Zentoria

[vietnamnewswire]

Jeito Capital leads a $105 million Series C financing in Alentis Therapeutics to advance transformational medicines for claudin-1 in cancer & fibrosis

http://dlvr.it/SmRJzS