#YEAAAAAAAH

[destielmemenews]

"In a stunning and unprecedented decision, the Colorado Supreme Court removed former President Donald Trump from the state’s 2024 ballot, ruling that he isn’t an eligible presidential candidate because of the 14th Amendment’s “insurrectionist ban.”"

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[honeybyte]

fill 2 for @marveltrumpshate charity auction!

for @haileythesato, thank you so much for your donation!

[tiredsoundsofagnes]

we celebrated two years of being together by hitting the vegan buffet!!! we are gonna bake something nice after a little nap. im so happy i get to spend the rest of my life with @stonedeadforever ❤️‍🔥 say congrats or suffer The Lovers Curse

[gasstationpopcorn]

cc: gt(?), naš časopis, 2022

[stiwnty]

YOOOOOO

The newslatter finally arrived and it ACTUALLY delivered to me this time!!! Here some thoughts:

1. At first I was like: Oh thats an interesting/odd ball, but if you look at it closer its actually the Chrome icon!

It has the colors and the blue dots. Its interesting and it also means that the icons are 3D. Then maybe apps like Adobe Animate are cubes with some depth??

~

2. I think that screenshot is hinting the Bob Is Always There short, look!

Kinda funny

~

3. Third but not least... 3D!!!! YEAAAAAHHHH!!!! Considering the only shot from inside the PC we've got so far is kinda simple it really makes me happy to get to know better the screen!!

~

4. Bonuss... Do you think these vids have to do something with the AvM videos uploaded into Youtube?? (Maybe, maybe not cuz AvA 1 and Showdown were alse there idk)

[sneeb-canons]

Hcs for the silly PH dudes because they deserve love

Tmph very much prefers to wear just socks as opposed (I think that was the expression??? Idk) to shœs. You will (probably) never see that man wearing shœs.

Thdph can do magic tricks!!! Especially with cards!!!!

Wwph knows japanese!!

Cjph likes drawing, he isn't the best at it due to losing practice but he still likes it :]

Headcanon #670

[jaynosurname]

Finished Hi Fi Rush.

First takeaway….

NO ONE TOLD ME THEY WERE GAY WHAT THE HELL OH MY GOD AHASBDHSHSBDHRISBSHSDHSIJSBSIDJSNSISISISSHSUSUSSYYESSSSSS

[dominiqueramseyart]

After so many years, i've finally bought a regular drawing tablet to use again.

I do like the cintiq, but I found myself still looking directly at the computer screen instead of the cintiq.

[astrothedreamdemon]

So I started reading he is brutal the snipersscout speedingbullet fanfic because I finished Running blind and taking shots. (Waiting for the next chapter)

And like I’m not even at the first chapter proper I’m at the prologue and I’m kicking my feet giggling. The descriptions of thrones and setting is so well done guys go read it

edit; OH BTW GO FOLLOW @sweetcookie500 THEY WROTE THE FIC

[178owintersball]

ok ok oKAY STAY CALM BC HOW IS BUCK’S APARTMENT SMOKEY WITHOUT THE SMOKE DETECTOR GOING OFF????

AND EDDIE LIED TO BUCK AND CHRISTOPHER TO GO CHEAT ON HIS GIRLFRIEND???

SO IF BUCK APARTMENT DID BURN DOWN NOT ONLY WOULD IT BE AWFUL BUT EDDIE WOULD BE SO RACKED WITH GUILT THAT HE LIED HE WOULD LITERALLY FORCE BUCK TO STAY WITH HIM

MARISOL WOULD BREAK UP WITH HIM WHEN SHE REALIZED WHERE HE WAS SO SHE WOULDNT BE AN ISSUE

TOMMY WOULD PROBABLY STICK AROUND FOR A SHORT TIME BEFORE ACKNOWLEDGING THE GAY ELEPHANT IN THE ROOM

THIS IS HOW WE WIN

[faecaptainofdreams]

*doesn’t think much about WOY for 2 days*

*suddenly Wander being comforted by Sylvia enters the chat*

Ohhhh YEEESSSSSS 🥰🥰😭😭😭💕💕💕

MY SERROOTTOONNNIIINNNN 💓💓💓💓💓💓

[australet789]

Did i also forget to mention that i need to have an electrocardiogram because my rest heart rhythm is too close to the 100s?

[magz]

New antibiotic kills pathogenic bacteria, spares healthy gut microbes

Article Date: May 29, 2024

Article Blurb: 

Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis while sparing healthy microbes in the mouse gut. The drug, called lolamicin, also warded off secondary infections with Clostridioides difficile, a common and dangerous hospital-associated bacterial infection, and was effective against more than 130 multidrug-resistant bacterial strains in cell culture.

[...]

Numerous studies have found that antibiotic-related disturbances to the gut microbiome increase vulnerability to further infections and are associated with gastrointestinal, kidney, liver and other problems.

[...] In a series of experiments, Muñoz designed structural variations of the Lol inhibitors and evaluated their potential to fight gram-negative and gram-positive bacteria in cell culture. One of the new compounds, lolamicin, selectively targeted some “laboratory strains of gram-negative pathogens including Escherichia coli, Klebsiella pneumoniae and Enterobacter cloacae,” the researchers found. Lolamicin had no detectable effect on gram-positive bacteria in cell culture. At higher doses, lolamicin killed up to 90% of multidrug-resistant E. coli, K. pneumoniae and E. cloacae clinical isolates. 

When given orally to mice with drug-resistant septicemia or pneumonia, lolamicin rescued 100% of the mice with septicemia and 70% of the mice with pneumonia, the team reported.  

Extensive work was done to determine the effect of lolamicin on the gut microbiome. 

“The mouse microbiome is a good tool for modeling human infections because human and mouse gut microbiomes are very similar,” Muñoz said. “Studies have shown that antibiotics that cause gut dysbiosis in mice have a similar effect in humans.”

Treatment with standard antibiotics amoxicillin and clindamycin caused dramatic shifts in the overall structure of bacterial populations in the mouse gut, diminishing the abundance several beneficial microbial groups, the team found.

“In contrast, lolamicin did not cause any drastic changes in taxonomic composition over the course of the three-day treatment or the following 28-day recovery,” the researchers wrote. 

Many more years of research are needed to extend the findings, Hergenrother said. 

[More in Article]

Note: The main scientific journal itself is paywalled (and not yet available in unpaywall nor sci-hub), Nature Journal Link

[that1notetaker]

@nokmietarchive

CAN we be friends?? BECAUSE YEAH!! THATS IT!! And also the? wanting to understand things on a fundamental level?? You tear things apart and get to understand every step, you know? It makes things make sense. A beautiful piecemeal. OH and!! I've seen your art around and I liked it a lot!! Plus your Genius Built Header drew me in like a moth to a flame. Actually, I wasn't going to post these, but here----

Look. Donnie is the PERFECT excuse to draw funky machines. He's got ALL the cool tech designS.

[ropebunnykant]

GUESS WHOS SEEING SABRINA CARPENTER BITCHES

[merrykristmus]

celebratory caliborn drawing (I got an apple pen for my birthday!)