#THE HUMAN HALF / * && ( HUMAN M!A )

[lordgrimwing]

Ages

(as in: you're how old?!)

Another gala made infinitely better by Elrond’s presence. Gil-galad relaxed in the carriage, legs extended across the slightly bouncing box (he’d never claim it was a great carriage. Whoever made it clearly had more whimsy than sense, which matched his air at parties. It was perfectly serviceable) to the plush bench across from him. 

Elrond (his savior from all things dull and boring and political) looked at his soft, embroidered slippers and shook his head. Clearly, he still thought the footwear choice for the evening was ridiculous despite how Gil-galad displayed himself to his best ability on the dance floor. He, of course, wore practical wood bottomed shoes that wouldn’t have a hole in the heel after a night of stifling reserved and polite revelry—how very Elrond of him. 

Endearing really. At least he’d worn the pair Gil-galad commissioned special for him last year and not the pair he wore to work in the healing halls (very practical, amazingly comfortable, very not suited for someone under his patronage). 

As usual, the evening started with Elrond nearly clinging to his arm as he introduced him as the ‘bright, up and coming physician’s apprentice’ he’d snatched up. They made the rounds, said all the proper ‘how do you does’ to all the right people, avoided the people he really did not want to talk to (they would have wanted to talk politics with him and strategy and career opportunities, which he just wasn’t in to) (was it too much to ask to remain where he was, fair outside of the High Family’s notice?), and ate some truly divine petit fours. Gil-galad had to defend Elrond’s place on his elbow or risk losing the witty commentary on the events to some lord or lady wanting to snatch him off for a dance or three. Made him feel very noble, defending his friends honor from the horrors of the petty nobility who definitely just wanted to know him for his connection to the crown (or to the dispossessed wandering sons of Fëanor who some thought had the greatest claim to the throne and whom Elrond just so happened to be raised by).

Overall, a blinding success yet again.

There was one thing that weighed on his mind. 

Elrond was so charming and graceful despite that wild upbringing with the nomads, it was easy to forget he hadn’t always been connected to Lindon’s lower court. Sometimes things came up that everyone knew about because they were either in the vicinity when it happened or because it came up every few years on polite gossip and reminiscence—everyone, that was, but Elrond. 

This time, it was a joke. Well, not so much a joke and half of story about a certain blond prince and his penchant for unsavory wildlife, but everyone knew the best parts that went without saying (because as it turns out one should generally keep the more lurid details of a minor and hilarious scandal out of everyday chatter when a High Prince was involved, just in case) and found the story perfectly timed and execute and laugh worthy. Gil-galad himself halved until he had tears in his eyes and Elrond had to rescue his drink so he didn’t spill it on the floor, or worse, on his brocade robe (a pain to have cleaned. More reason to keep Elrond all to himself and never lose his sensible head). After that, Elrond turned to him in all seriousness with far more questions that he could answer in a full room.

Because, of course, Elrond hadn’t been here. He hadn’t been in Lindon. He hadn’t been born. Surely his parents (well, the mortal one at least. The elf father (because it was always the elf who sired in these cases. Peculiar and perhaps worthy of later exploration) most likely was traipsing around somewhere) had still been many generations from being born. He didn’t know. 

He was young. All half-elves were, not that Gil-galad had met many others but one did hear about these kinds of things. They were only half elf, after all, and the other half was mortal (humans, almost exclusively, though he heard rumor of a dwarf once), and being half mortal they had a habit of dying like mortals. Unfortunate. He liked not thinking about that.

So, how old was he? 

Gil-galad squinted across the carriage at him, thinking. 

“What?” Elrond asked, staring back at him. “Is there icing in my hair again?”

(The icing incident happened six months ago, and they’d all had a good laugh about it. He wouldn’t be opposed to picking pink icing out of that curly brown hair again).

“How old are you?”

He couldn’t be more than four-hundred years old, maybe as young as three-hundred. His face had some lines but nothing like the older mortal races or even the truly elderly elves (like Círdan, the old gaffer, still insisting he could take his little sailboat out alone like he wasn’t the oldest elf this side of Cuiviénen—wherever that was). A reasonable age. Just a bit younger than him. A good age for dealing with minor nobles. 

“About one-hundred and seventy. Why?”

And living in the middle of nowhere would explain why he missed out on all the good gossip and—wait. 

“What?”

Elrond shrugged his narrow shoulders (but not too narrow. He’d seen how they’d started filling out over the last few years). “Well, I don’t know exactly. Birthdates didn’t seem all that important in the middle of a plague village.” 

“You’re a baby!” The first thing he thought of popped out of his mouth, as sometimes happened when he was relaxed.

“I’m well past elven majority, thank you.” Elrond sounded incensed. “And I’ve seen humans grow up and die, so I’m far from an infant.”

“A hundred and seventy,” Gil-galad repeated, pulling his diverging thoughts back to some semblance of focus. “You’re not even two-hundred and I’ve introduced you to the vices of drink and leaf!”

Elrond snorted. “Dwarven pipeleaf is a superior cultivar, and Maglor gave us rags soaked in aloe liquor to suck whenever we were teething. The only thing you’ve introduced me to is decidedly tame dancing.”

“And the best peaches you’ve ever tried,” Gil-galad insisted, still off balance (he could have done without the reminder that Elrond grew in his teeth all wrong as a child and new ones just kept popping up every few months. At some point he got a whole new set of teeth as a child. Might his body just up and decide that he needed a third set at some point, like some kind of shark? He did not need that kind of body horror in his mind right now).

“And the best peaches,” Elrond agreed. 

Yes, yes, fruit was a topic he could manage.

“Tomorrow,” he announced, stretching his arms and folding them behind his head, “I am going to bring you dewmelon and mulberry in cream and you will never forgive me for not introducing you to it sooner.”

Elrond laughed. “Don’t you have council meetings and work all day tomorrow? That’s all you complained about yesterday.”

Gil-galad sat up, pulled his feet off the seat, and leaned forward. He put a finger to his friend’s lips, hushing him. “Elrond,” he said, “please don’t spoil my imagination with reality.”

He felt Elrond smile under his hand. 

“Okay, but only for tonight.”

[ashybaby]

original @asntde

[amykiriwosdefenselawyer]

so are we gonna talk about ameri's name literally being a ship name

well it's basically implied canon that merize is her mother

henri's name is technically "anri" in japanese, not henri

anri, merize

ameri?

[strayrainbow]

@ladylunora 's DTIYS! another one!

Still thinkin of Them, obsessed with their dynamic, I just love drawing them and nothing else apparently

Happy Halloween!

[selamat-linting]

just because i find a guy hot, doesn't mean i think he deserves rights nor he deserves any cent of my money despite sexualizing him day and night. most of the hot guys i'll be exposed to came from usamerica, capital of settler brainrot and fascism.

[40steps]

hey i’m a mutual who dropped out in 7th grade and i just want u to know that things will be ok. i’m going back to school this year and like you can just stop either temporarily or permanently. i promise u it will be ok

:((( thank u so much this means a lot to hear . my plan has been to drop out for like two years at this point but i never really expected it to feel this much like a huge change even though it was always going to be. and my mother asked me if i just wanted to drop out when i told her i didn't want to go in today and it's sent me on a downward spiral. sorry for putting this on your dash board whoever is online and whoever saw it.

[sapphire-to-the-rain]

happy pride to our cishet dance coach who played HOT TO GO! as our warmup song and then was appalled (jokingly) when our other lesbian coach had never heard of chappell roan

[pnuk-r0ck]

I want death

[dearestblood]

^ was supposed to be on the bridge 5 minutes ago. not going.

[chattier80]

Avi n Ethan

commissions | kofi | patreon | discord | twitter | twitch

[euclydya]

girlies it just hit 11 pm and the zoomies (human) r setting in WHAT the fuck is this shit

[bonestrouslingbones]

y'know what maybe it's a really good thing that i never got far enough into atbb to do that half-planned m!a to make them all humans for any period of time because i do kinda think russ would just die

[lovetogether]

All our ocs are double As unless we say otherwise

Ace and agender

[badluck990]

......Hang on I have the urges.

I must.

I must make the shitty 4kids changes to my work.

For the BIT!

Good news! Your latest project is being adapted into an animated form! Bad news, it's being adapted by 4Kids.

[kittybatboi]

🥸

[reasonsforhope]

A new treatment combining ReCET and semaglutide could eliminate the need for insulin in type 2 diabetes, with 86% of participants in a study no longer requiring insulin therapy. The treatment was safe and well-tolerated, and further trials are planned to confirm these results.

Groundbreaking research presented at UEG Week 2024 introduces a promising new treatment approach for type 2 diabetes (T2D) that has the potential to greatly reduce or even eliminate the need for insulin therapy.

This innovative approach, which combines a novel procedure known as ReCET (Re-Cellularization via Electroporation Therapy) with semaglutide, resulted in the elimination of insulin therapy for 86% of patients.

Globally, T2D affects 422 million people... While insulin therapy is commonly used to manage blood sugar levels in T2D patients, it can result in side effects... and further complicate diabetes management. [Note: Also very importantly it's fucking bankrupting people who need it!!] A need therefore exists for alternative treatment strategies.

Study Design and Outcomes

The first-in-human study included 14 participants aged 28 to 75 years, with body mass indices ranging from 24 to 40 kg/m². Each participant underwent the ReCET procedure under deep sedation, a treatment intended to improve the body’s sensitivity to its own insulin. Following the procedure, participants adhered to a two-week isocaloric liquid diet, after which semaglutide was gradually titrated up to 1mg/week.

Remarkably, at the 6- and 12-month follow-up, 86% of participants (12 out of 14) no longer required insulin therapy, and this success continued through the 24-month follow-up. In these cases, all patients maintained glycaemic control, with HbA1c levels remaining below 7.5%.

Tolerability and Safety

The maximum dose of semaglutide was well-tolerated by 93% of participants, one individual could not increase to the maximum dose due to nausea. All patients successfully completed the ReCET procedure, and no serious adverse effects were reported.

Dr Celine Busch, lead author of the study, commented, “These findings are very encouraging, suggesting that ReCET is a safe and feasible procedure that, when combined with semaglutide, can effectively eliminate the need for insulin therapy.”

“Unlike drug therapy, which requires daily medication adherence, ReCET is compliance-free [meaning: you don't have to take it every day], addressing the critical issue of ongoing patient adherence in the management of T2D. In addition, the treatment is disease-modifying: it improves the patient’s sensitivity to their own (endogenous) insulin, tackling the root cause of the disease, as opposed to currently available drug therapies, that are at best disease-controlling.”

Looking ahead, the researchers plan to conduct larger randomized controlled trials to further validate these findings. Dr. Busch added, “We are currently conducting the EMINENT-2 trial with the same inclusion and exclusion criteria and administration of semaglutide, but with either a sham procedure or ReCET. This study will also include mechanistic assessments to evaluate the underlying mechanism of ReCET.”

-via SciTechDaily, October 17, 2024

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Note: If it works even half as well as suggested, this could free so many people from the burden of the ongoing ridiculous cost of insulin. Pharma companies that make insulin can go choke (hopefully).