#Skin Graft Market

[blog-site-for-market-research]

Skin Graft Market Research: Understanding Size, Trends, and Outlook

Market Overview –

In 2022, the skin graft market was estimated to be worth USD 4 billion. The market for skin grafts is expected to expand at a compound annual growth rate (CAGR) of 7.01% between 2023 and 2032, from USD 4.28 billion in 2023 to USD 7.36 billion by 2032.

The skin graft market is witnessing steady growth driven by the increasing prevalence of skin-related conditions and trauma cases requiring surgical intervention. Skin transplant procedures, including autografts and allografts, offer effective solutions for wound healing and cosmetic reconstruction. With advancements in transplantation techniques and tissue engineering, the market continues to evolve to meet the growing demand for innovative skin graft solutions.

The skin graft market pertains to the healthcare sector focusing on procedures and products related to skin grafting. Skin grafting involves transplanting skin from one area of the body to another to repair damaged skin due to burns, injuries, surgeries, or skin diseases. This market encompasses various types of skin grafts, including autografts (from the patient's own body), allografts (from a donor), and xenografts (from another species), as well as synthetic skin substitutes.

The primary driver of the skin graft market is the increasing incidence of burns, trauma, and skin-related disorders worldwide. Burn injuries alone affect millions of people each year, creating a significant demand for skin grafts to promote wound healing and prevent complications such as infections and scarring. Additionally, advancements in surgical techniques, tissue engineering, and regenerative medicine have expanded the scope and effectiveness of skin grafting procedures.

Moreover, the growing awareness about the importance of aesthetic and reconstructive surgeries, along with the rising demand for cosmetic procedures, has further fueled the demand for skin grafts. Patients undergoing procedures such as Mohs surgery for skin cancer removal or cosmetic surgeries for scar revision often require skin grafts to achieve optimal outcomes.

The COVID-19 pandemic has impacted the skin graft market, with disruptions in elective surgeries, reduced hospital admissions, and changes in patient priorities. However, the pandemic has also highlighted the importance of wound care and infection prevention, underscoring the essential role of skin grafts in wound management and reconstruction.

Despite challenges such as availability of donor tissue, cost constraints, and variations in surgical outcomes, the skin graft market is expected to grow as innovations continue to improve graft survival rates, reduce complications, and enhance patient satisfaction. With ongoing research and development in tissue engineering, biomaterials, and regenerative medicine, the skin graft market holds promise for addressing the diverse needs of patients with skin injuries and disorders.

Segmentation –

The global skin graft market is segmented on the basis of graft type, graft thickness and applications. Based on graft type, the market has been segmented as autologous, isogeneic, allogeneic, xenogeneic and prosthetic. Based on the graft thickness, the market has been segmented as split-thickness, full-thickness and composite graft. Based on the applications, the market has been segmented as extensive wound, burns, extensive skin loss due to infection, skin cancers and others. Based on the equipment, the market has been segmented as dermatome (knives dermatomes, drum dermatomes, electric dermatomes, air dermatomes), general surgical instruments, consumables and others. Based on the end users, the market has been segmented as hospitals and clinics, academic and research and others.

Regional Analysis –

Regional analysis of the skin graft market reveals varying trends influenced by factors such as healthcare infrastructure, prevalence of burns and traumatic injuries, and availability of advanced medical technologies. In developed regions like North America and Europe, where there is a higher incidence of severe burns and extensive healthcare facilities, the skin graft market is well-established with a wide range of products and procedures available. Conversely, in developing regions with limited access to specialized burn care and reconstructive surgery, such as parts of Asia-Pacific and Africa, the market for skin grafts is still evolving. Moreover, cultural attitudes towards cosmetic and reconstructive surgery impact the demand for skin graft procedures across different regions. As awareness of the benefits of skin grafts for wound healing and aesthetic enhancement increases globally, there is a growing opportunity for market expansion through education, training, and technology transfer initiatives to address regional disparities in access to advanced skin graft solutions.

Key Players –

Skin graft companies include Organogenesis, Specimen Medical, Stratatech Corp, Tissue Regenix Group Plc, Avita Medical, Convatec Inc, Medtronic, Coloplast, Braun Melsungen, Stratatech Corporation, and Zimmer Biomet.

Related Reports –

Clinical Alarm Management

Opioids

Fertility Drug and Surgery

Endodontic Devices

For more information visit at MarketResearchFuture

[stomeranclels451]

https://ai.wiki/read-blog/90366

Skin Graft Market Share, Growth Factors, Competitive Landscape and Forecast to 2030

[creativeera]

The Growing Acellular Dermal Matrices Industry is Thriving on Advanced Wound Care Innovations

The acellular dermal matrices market caters to the need for advanced wound care products that facilitate faster healing of complex wounds and burns. These tissue grafts derived from donated human or animal dermal tissue serve as a scaffold that aids skin or soft tissue regeneration. Comprising an intact matrix of collagen and protein fibers that stimulate cell migration and new tissue formation, acellular dermal matrices reduce healing time and scarring for wounds that fail to heal naturally.

The Global Acellular Dermal Matrices Market is estimated to be valued at US$ 10.14 Mn in 2024 and is expected to exhibit a CAGR of 5.9% over the forecast period 2024 to 2031. Key Takeaways Key players operating in the acellular dermal matrices are Merck & Co., Inc. (Merck Animal Health), Ceva, Zoetis Services LLC, Boehringer Ingelheim International GmbH. The growing prevalence of chronic wounds and ulcers due to the high incidence of diabetes and old age related disorders has bolstered demand for advanced wound care products. North America dominates the market currently due to favorable reimbursement policies and growing awareness about advanced wound management. However, the rising geriatric population in Asia Pacific and Latin America is expected to drive the market expansion in these regions during the forecast period. Market key trends The increased adoption of Acellular Dermal Matrices Market Demand for use in plastic and reconstructive surgeries indicate one of the key trends in the industry. By serving as a dermal substitute, these grafts enable surgeons to repair soft tissue deficits and skin defects with reduced contracture, distortion, and scarring for procedures like breast reconstruction and hernia repair. The advantages over autografts like reduced donor site morbidity have augmented their uptake in cosmetic surgical procedures.

Get more insights on Acellular Dermal Matrices Market

Unlock More Insights—Explore the Report in the Language You Prefer

French

German

Italian

Russian

Japanese

Chinese

Korean

Portuguese

Alice Mutum is a seasoned senior content editor at Coherent Market Insights, leveraging extensive expertise gained from her previous role as a content writer. With seven years in content development, Alice masterfully employs SEO best practices and cutting-edge digital marketing strategies to craft high-ranking, impactful content. As an editor, she meticulously ensures flawless grammar and punctuation, precise data accuracy, and perfect alignment with audience needs in every research report. Alice's dedication to excellence and her strategic approach to content make her an invaluable asset in the world of market insights.

(LinkedIn: www.linkedin.com/in/alice-mutum-3b247b137 )

[frownyalfred]

I love when Batman villains are obsessed with branding/marking the Bats. They have zero idea they’re fucking with the man who has like 10 dermatologists and three of the top black market plastic surgeons in the world on call to fly into Gotham at any time. The man eats drinks and breathes reconstructive surgery. He could pay for a whole new body’s worth of experimental skin grafts. Superman gets jealous of his skin quality sometimes.

[lifblogs]

It Does

Week 6 @summer-of-bad-batch Prompt: Battle Scars Rating: General Audiences Word Count: 993 Summary: Hunter works up the courage to ask Crosshair if the scars on his head ever hurt. READ ON AO3

“Does it ever hurt?” Hunter asked, words halting.

He and Crosshair were down by the docks, dusk painting the sky in purple and gold, the waters now dark, comfortable shadows enveloping them. The soft lapping of the water against the wood and the docked boats was soothing, which was probably the only reason Hunter had worked up the courage to even ask this.

“Does what hurt?” Crosshair spat. 

Oh, classic Crosshair.

“Your scars—the ones on your head,” Hunter explained.

“Did you take me down here just to talk about this?”

“No.”

He had just wanted a quiet moment with his brother—he felt all the work they were doing on their house recently had made it so they were always busy, always doing something. Most days Hunter appreciated that, the soldier in him always ready to be on the move, to strategize, to organize, to lead. He was still learning to take breaks, even when he woke up in the middle of the night, having a horrible fear clenching over his entire torso, and stealing his breaths, telling him he was in danger, that his family was in danger, that he was in the middle of battle. He didn’t tell anyone, but he used those moments to work on their home. Today he was just tired, so tired, and he was doing his best to listen to that for once. He had to remind himself he actually had the luxury to.

“I just think we needed a break,” he explained. “Besides, Wrecker, Tech, and Phee took Omega to that night market Shep’s hosting.”

“Yeah, that wasn’t really my scene.”

“So… the scars,” Hunter ventured again, guilt flooding his chest right above his stomach, like he’d swallowed too much of something too quickly, and it burned going down. “Do they—”

“Yes,” Crosshair admitted.

They sat for a bit, listening to the gentle water.

“Of course it hurts,” Crosshair went on. But his words weren’t bitter despite his tone. “Bacta helped to heal from it, but they had to do a skin graft.”

Hunter turned to look at his brother, to look at the scar.

“I don’t blame you,” Crosshair said. “I think I did for a long time, and in a way, I still hurt, but I see the choices we thought we had to make. What happened was inevitable. Besides, I shot you. You should be the one complaining.”

Hunter leaned back, resting his weight on the palms of his hands, watching the gold transform further into a to a deeper purple before his eyes. The lamp he’d brought with them that could sense when it was dark turned on, adding a soft, golden glow to their surroundings, lighting up Crosshair’s scar, casting shadows to the deeper pits in it.

Hunter made himself look, not because the scar was strange, but because he wanted to face the truth of it.

His brother was in pain.

“Sometimes I think my choices hurt more than the scar does,” Crosshair admitted. “I, uh… I had my inhibitor chip removed afterwards. It was my choice. I had AZI do it. I hid it from the Empire.”

Hunter’s eyes widened, and he looked at his face, the face that was still so-often closed off, that was working on showing honesty.

“What?”

“I didn’t want to say it before,” he went on. “It didn’t matter much to me because…” He sighed. “Because, well… I believed in the Empire, even without the chip. I tried so hard to believe in them, to believe they cared, that they’d given me a place, a purpose. I’m s—”

“Don’t apologize,” Hunter said.

Now it was Crosshair’s turn to look at him with confusion. “Why not?”

“The Empire hurt you in ways I didn’t understand—in ways none of us understood. You were working with the information you had, just like I was.”

Crosshair gave a slight shrug, and looked back to the water, kicking his feet.

“Heh, I guess so.”

“You still blame yourself, don’t you?” Hunter asked.

“Just as you do,” Crosshair responded, as sharp as ever, still able to not only pinpoint a precise target, but to understand everything he saw and took in. Watching others had given him a keen understanding of humanity, maybe one even stronger than the one Hunter’s enhanced senses gave him.

Hunter let out a deep exhale, the sound filling his ears, interrupting the beat of his brother’s heart to his senses.

“Yeah,” he admitted. “It’s stupid,” he eventually said. “We’ve been through so much, and we still have these—these battle scars.”

“What, you think scars just go away?” Crosshair asked, tone almost teasing, glancing at Hunter with an expression that anyone outside their family would have thought was disgust.

“No, but… time’s passed, and yet it’s still there. Why does it work that way? What is it doing for us? You know what I mean?”

“I do wish they would leave,” Crosshair admitted. “I don’t… hate you, Hunter. I’m not sure I ever really did.”

“Well, that’s a relief.”

Crosshair huffed out a laugh, and shoved him.

“You’re right though. It would be nice if it could stop hurting.”

“Does it ever?” Hunter asked, referring to Crosshair’s physical scars as well.

Crosshair smiled at him—he actually smiled (Hunter was so going to use this as blackmail)—and he said, “Yeah, it does.”

Hunter knew where his mind had gone, and his had inevitably gone to the same place: Omega, their family.

Hunter stood, grabbing the lamp, and then held out his hand to help Crosshair up. For a moment he felt his chest constrict (but in the most pleasant way) when Crosshair took his hand without hesitation. This was his brother, and he was happy to be with him, and it seemed Crosshair felt the same.

“Come on, I’m still hungry,” Hunter admitted. “Let’s go meet up with the others and see what food the night market has.”

“Thought you’d never ask.”

[seat-safety-switch]

If you're like me, then you were born allergic to two things: most tomato-based dishes, and bullshit. Our era's defining characteristic is the latter: we are immersed, nay, assaulted by a fine spray of bovine fecal product at all times, from all possible angles. And now, the folks who once told us that magazines were unprofitable have made a machine that spits out words if you feed it just one rainforest.

Well, folks, we here at Bad Cars Monthly are not going to stand for this kind of thing. Writing well-intentioned but ultimately meaningless hoo-ha in order to pad the word count is our fucking racket, and we're not going to let any glorified Logo turtle play around in our territory. That's why we've decided to go low-tech, as a form of protest. The technology industry demands that we buy the newest and hottest machines, even when we predominantly write about machines made fifty years ago.

Every BCM contributor has been assigned one (1) Coleco Adam microcomputer with English-alphabet daisy wheel printer, and they will be mailing their work products and drafts to our offices. Yes, this means that at least one of the articles you are reading right now made at least two trips in an Iron Duke-equipped Grumman LLV. Low compression. Inexpensive. Durable. That's what the marketeers would call "living our values," if we hadn't already fired them to save more money for postage. And running up the odometer means it's just that much closer to being able to grab one at government auction, so we can try to finish Nightmare Ed's special article series, Going Under 17 Seconds In The Quarter-Mile With A Grumman LLV And Only Some Skin Grafts. I love that man. He even pads the title.

All this is to say, if you're a real, live, flesh-and-blood writer, or just someone who would like to have a Coleco Adam in their house and can write convincing enough garbage to trick us into publishing it, send us a self-addressed stamped envelope with said garbage. Please also include photographs of your Plymouths.

[literary-illuminati]

2024 Book Review #25 – The Tainted Cup by Robert Jackson Bennett

The fact that I put in a hold for this is basically a triumph of marketing. I saw Jackson Bennett doing an AMA to promote it, which reminded me that a) he existed and b) I liked the one book of his I’d read. So 20 people in the hold queue ahead of me latter, I finally got a chance to give it a try. Shockingly, this actually worked out incredibly – this was easily one of the most enjoyable reads I’ve had all year.

The book follows Din, a recently promoted Assistant Investigator mainly notable for the incredible invasive grafts and suffusion that left him with grey skin, dyslexia, and a literally edetic memory. The last bit is the most relevant, as his incredibly eccentric Investigator uses him as combination Watson and CSI, running around collecting all the evidence and conducting most of the interviews so she can make her grand deductions in peace.

The case in question is the murder of an esteemed and well-regarded commander through the unconventional method of a tree sprouting in his chest cavity and growing several feet over the course of as many seconds. As things are wont to, the investigation quickly spirals out of control, dragging the investigators to a logistical hub days from the Seawall protecting the empire from leviathan attacks and implicating true imperial grandees.

So, this is a murder mystery. An extremely high concept one, full of leviathan-blood enhancements and supernatural contagion and a whole society structured and organized around the constant struggle to stave off apocalypse, but ultimately still very much an intentionally tropey murder mystery. Every clue is mentioned as Din notices it, always before it’s relevance to the plot is revealed. There’s an extended reveal where the Investigator just lays out the whole mystery as she’s’ deduced it and baits the villain into doing something stupid. One of the supporting cast is revealed to have been one of the killers all along. The entire thing occurs with a ticking clock meaning the investigation has only days to find an answer. It’s all there.

To be clear, this is not at all a complaint. Maybe it would be if I read more mysteries, but as it is the whole set of tropes is a very rare treat for me, and it’s all executed very well. And I adore a well-done drawing-room reveal scene. Not that I did, but I appreciate that I could have tried to outguess the plot and figure out the whole mystery ahead of time from the clues given (instead of just noticing most of them and having a vague sense of where people were headed – though I def thought the governor’s second paying a weird amount of attention to Din was a threat and not the love interest). The whole thing was just a joy to read, even if the characters were all a bit exaggerated and archtypal, and the ending was a bit too neat and tidy for my tastes.

The setting isn’t exactly novel – creepy quasi-horror rich biopunk settings and horrible kaiju whose corpses warp the world around them being harvested and processed for raw materials became fairly well trod ground at some point – but it’s hardly generic or the expected standard either. It’s very well-executed, and the murder mystery conceit basically requires each new relevant addition to the story being clearly explained as we meet it, which was handled with surprising grace/without devolving into multipages reams of exposition too often.

It was very amusingly obvious (and then confirmed in the acknowledgements!) that the entire subplot about ‘preservation boards’ (bodies to ensure there’s no unintended side effects of growing/processing weird biopunk reagents in a given region) being abused to obstruct and delay vital progress to – literally – raise property values for the landed gentry, was directly inspired by Jackson Bennett having read a lot of articles about malicious abuse of environmental protection legislation in the US.

Politics-wise – I mean it’s a conceit of the whole story that the empire is essentially, if not benevolent, then at least necessary and well-intentioned. Riven with corruption and patronage networks, warped for the interests of the landed elite, full of negligence and despair – but at it’s core a good thing to work for, and receiving awards and mandates from on high is a good thing. The issue is the boyars and not the tsar, all that sort of thing. Which works for the story, but I’ve at this point read enough SF/F that really digs into the whole empire thing that the lack of subversion there took me almost by surprise.

Not that the empire’s all nice – the grafted specialists with superhuman strength or eidetic memory or perfect reasoning skills all die after a decade or two of service, and that’s just the price of keeping things running. A major subplot of the whole book is Din trying to hide the fact that his enhancements misfired slightly to make him functionally dyslexic (an issue, when your main value to be a perfect living archive). Not entirely sure if the series is really going anywhere with the whole disability theme beyond the very basic ‘the empire will only survive if it makes it possible for EVERYONE to contribute what they can’ beat it hit in this book – regardless, the fact that Din spend the entire book wondering what had been done to her boss’s brain that e.g. she spent most conversations blindfolded to help her focus, and while doing so can identify most forms of text on a page by touch, only to find out that no she’s just autistic was very funny to me.

[lullabyes22-blog]

Snippet - Forward, but Never Forget/XOXO - The Council

Silco meets the Council. And ponders his history.

Forward, but Never Forget/XOXO

Snippet:

Hatred rises like a toxic effervescence in Silco’s veins.

(These Pilties, eh, Vander?)

(These fucking Pilties.)

In a city whose lifeblood is old money, they are the crème de la crème: an elite group steeped in Piltover's rich heritage of trade and commerce. A century ago, the city was a drowsy backwater, a middling port of fishing settlements and warehouses. The Council's forefathers were Shuriman midshipmen, Ionian merchants, Noxian brigands and Demacian bureaucrats. Men and women who made their fortunes through sheer tenacity and hard graft.

Then came the boom.

Beneath the settlement lay caverns with rich deposits of minerals. Soon, smelters dotted the waterfront, and shipyards sprang up along the bay. Steel became gold. Iron turned to platinum. The age of industry dawned: Piltover blossomed into a manufacturing metropolis.

Then came the Void Wars. In a trice, the city's population doubled. Zhyunian refugees fled by boat; Noxian merchants came by steamships; Demacian scholars boarded trains and Freljordians rode in on zeppelins. Language diversified; the city grew cosmopolitan.

In the coming decades, successive waves of migrants were swept onto Piltover's shores: from noble families seeking to expand their power across Valoran to small-town traders laden with cheap luggage and big dreams. By the century's end, they'd propelled Piltover into a global megacity of palatial mansions, art deco skyscrapers and pristine streets hosed clean every morning before the business hubs threw open their gilded gates to the bon ton.

The population boom meant more houses to build, more food to eat, more clothes to wear. All of which required labor, capital investment, and raw materials.

All of which came from the Fissures.

In theory, the Undercity should have prospered hand-in-hand with Piltover. Yet little of the riches from the Fissures’ recesses was ever relished by the Fissurefolk themselves. They were cut from a different cloth from their over-the-Pilt brethren. Their ancestors were miners and craftsmen, not shipmasters and merchants. Their culture was a clotted stew of customs and dialects; most didn't even speak Piltovan. They weren't born in the city itself but in its shadow, living in close-knit riverside settlements and twilit caverns.

Physically, they resembled deepwater piranhas compared to their sun-kissed kin—narrow bones, wan skins and sharp teeth. Culturally, they were foreigners. And socially, they were inferiors.

Their economy was a rich relic of the Oshra Va'Zaun empire. Their gemcraft and metalworking industries were well-established. Their artisans were peerless and prolific. Their alchemical scholars were the backbone of innovation. They had a robust labor force, a thriving entrepreneurial class, and a history of keen ingenuity.

Their forbearers traded along a flourishing network of maritime ports and river routes. They bartered with Bilgewater; bankrolled the gold mines in Shurima; forged trade deals with Ionia. They even had stakes in the black markets of the Shadow Isles and the mercenary guilds of Noxus.

They did business with every corner of Runeterra. And they did so proudly.

A century's time would turn the glad tidings into bitter tides.

During the first wave, the Undercity's wealth was a windfall for Topside. The demand for labor and resource was insatiable. But the Undercity's resources were finite. When Piltover's population ballooned after the Void Wars, the Fissurefolk were forced to compete. Lacking the natural advantage of fertile terrain and plentiful sunlight, they had no choice but to cut corners. In a trice, the factories and mines teemed with orphans and the elderly, each one paid starvation wages and offered none of the protections aboveground. By the century's end, the Undercity was squeezed dry, a sweatshop with a single employer.

Piltover.

As the upper-city's wealth quadrupled, mercantile clans rose up, each vying for control over the mineral deposits in the Fissures. These overlords were no friends of the poor. Their purview was profit, and profit meant one thing above all else:

Exploitation.

Their first order of business was stymieing the Undercity's trade routes and keeping its resources under lock and key. The collapse of the old Sun Gates and the flooding of the Undercity’s ports gave them the perfect pretext. The borders were sealed off in the guise of a safety net. The only routes were now through Piltover's Bridge, and each shipment was heavily taxed.

In time, the Undercity’s local markets choked. A slow strangulation of wealth reduced former artisans and alchemists to scavengers. Tariffs trapped them in a perpetual cycle of debt and debasement. Once-proud traders stooped to selling their own daughters for coin. Others tipped over into outright smuggling.

Then Piltover launched its second phase: a systematic strangulation of the Undercity's voice.

Fissurefolk were barred from owning or leasing property aboveground. Their children were denied access to Topside schools. Their customs were deemed barbaric. Their traditions were branded as backward. Their dialect was derided as guttural filth. They were derogatorily referred to as Sumprakers—as if their entire existence was an aberration.

By the century's end, Piltover had transformed from a trading partner into a hegemony. The Fissurefolk were no longer perceived as citizens, but as the Other.

An enemy within.

Soon, Topside began consolidating power by buying up land around the Fissures. Displacing the poor and demolishing their homes, they drove them deeper and deeper belowground, while putting the leftovers to use. Historic districts were privatized. Temples were razed. Marketplaces were shut down. The Undercity was reduced to a febrile womb of raw material, ready to be ravaged.

And ravaged it was.

When the first mining rig was installed, the Fissurefolk rioted. The unrest was put down. More mines followed, and more violence. It wasn't until the Enforcers were established as a body of justice that the tide turned in Topside's favor. These overseers were a law unto themselves, their ranks composed of mercenaries and miscreants. Their uniforms were black; their hearts were blacker. Their methods were a brutal amalgam of medieval torture and modern bureaucracy.

Under the banner of peace, the Enforcers were tasked with quashing dissent belowground.

They did so—brutally.

Piltover's third phase was total dominion.

The first mercantile houses had grown rich off the Undercity's spoils. But the new generation hungered for something more: absolute rule. They were no strangers to political maneuvering. Their forefathers had been shrewd tacticians: men and women who'd honed their wits through war, diplomacy and backroom deals.

They knew how to twist the knife, and keep their own hands clean.

Before long, they'd allied with Piltover’s industrial magnates and the monied elite. Together, they formed a cabal of oligarchs, each as ruthless as they were influential. Thus, the Council was born: a body of seven self-appointed sovereigns charged with regulating trade, enforcing laws and levying taxes.

They saw the Fissurefolk as a means to their own end. Disregarding their petitions for better sanitation, downplaying the contributions of their labor, and turning a blind eye to the rampant pollution, they proceeded to carve the Undercity's soul from its body.

When the Fissurefolk protested, the Council responded with Enforcer raids.

And bloodbaths.

By century's end, the Council had built a wall of bureaucracy between themselves and the Fissurefolk—most of whom were treated with neo-colonial contempt. Meanwhile, their wealth continued to reach dizzying heights, with every merchant ship that sailed through the port's grand arches and every sculpture patronized by celebrated virtuosos in their mansions.

The Hex-Gates only quadrupled their fortunes. With every invention by Talis, investors flocked and the Council’s influence grew. The wealth they had hoarded was now limitless. They could build a brand-new city, if they so desired. But why should they, when the Trenchers had already done the hard work for them?

Today's Council—Hoskel, Salo, Bolbok, Shoola, Medarda, Kiramman—are Piltover's pivotal political force, decreeing laws with a gesture from their grand parlors. They're the ones who decide whether jobs are created or lost, how many schools are funded, what taxes are levied.

They make decisions that affect every citizen in the city—every bloody day.

They are also corruption incarnate. Yearly, they’ve swallowed over one-third of the allocated Undercity budget, without accounting for a single cog. Between them, they preside over an empire of private business interests in everything from real estate to racehorses, stowing away their wealth in Demacian bank accounts, Noxian jewelry splurges and private islands dotting the annexed Ionian shores.

To them, Silco's coal-mining origins are as offensive as a rat turd in their caviar. Among Topside's upper-crust, he's a social climber, a rabble-rouser, and a scabrous opportunist. He wasn't born into privilege: he made his wealth through the cutthroat crudeness of industry.

More offensive still, he keeps a singlehanded stranglehold on his fortune, no different from a smuggler stowing all his coins in his codpiece. He never invests in stocks or allows Piltovans to buy shares in his enterprises. Like his factories, everything he owns belowground—publishing houses, restaurant chains, repair garages, gyms, nightclubs, salons—employs Fissure-bred workers, and is rumored to be a front for funding anarchism.

As if that weren't bad enough, he has no inhibitions in debating money or politics in their glittering ballrooms. Worse, he mocks them for entertainment—all while displaying impeccable manners.

Case in point—

With grave courtesy, Silco bows his head, "Councilors."

[bryaraga]

what do you *mean* you got a flesh eating fungus at walmart????

ah yeah. i forget, my lore isn't known on here

so imagine. the year is 2016, it is right before the holidays. i am a very tired 19 year old, working for big Mart. i am not eating well, being heavily overworked, and genuinely unable to shop anywhere/anytime other than after getting off work at the walled market.

i notice a black spot on my gums, which a week later has me hospitalized. hallucinating, swelling, vomiting. basically every symptom of Not Being Well you can think of. i'm told i have a very low chance of survival, as it is rapidly causing cell death in my jaw.

i'm told they will have to remove a large chunk of both my jaw and tongue. i make a lot of jokes about me no longer being able to perform fellatio. the surgeons do not find me funny. i tell them to give me a robo-jaw. they also do not find that funny.

anyways, i now have a baseball sized skin graft and a titanium bar in my face. i count this as like. a third of a robo-jaw. i can still perform fellatio.

[blog-site-for-market-research]

Skin Graft Market Outlook, Global Outlook & Forecast 2023-2032

Market Synopsis of Global Skin graft Market:

In 2022, the skin graft market was estimated at USD 4.00 billion. The skin graft market is expected to increase from USD 4.28 billion in 2023 to USD 7.36 billion by 2032, with a compound annual growth rate (CAGR) of 7.01% over the forecast period (2023-2032).

Key players of Global Skin graft Market:

Key players profiled in the report are Organogenesis, Inc., Specmed Medical, Stratatech Corp, Tissue Regenix Group PLC, Avita Medical, Convatec Inc., Medrotonic, Coloplast, B. Braun Melsungen, zimmerbiomet, Stratatech Corporation, Zimmer Biomet and others.

Current Industry Trends:

U.K.’s National Health Service researchers are expected to launch a liquid skin dispersing device which contains a regenerative epithelial suspension which mimic natural skin and reduce wound healing times

Allograft skin graft is expected to lose market share in favour of xenogeneic and prosthetic segments. The advancements in skin graft technology such as biocompatibility and biomimetic material is a reason for the expected development coupled with the drawbacks of allografts such as large surgical footprint

Mergers and acquisitions are ripe as the skin graft market outlook is highly technology oriented with large development cost and times. To cut short development efforts and to take advantage of complementary specialities of other companies are the cause of the mergers and acquisitions. For example, Mallinckrodt plc, entered into a merger agreement with Stratatech Corporation in August 2016 to take advantage of reduced development efforts for StrataGraft regenerative skin tissue and a technology platform for genetically enhanced skin tissues.

Start-ups are a growing trend, as a company with proprietary technology will have an advantage over a larger competitor due to low volume and high value nature of the product, which negates the economics of scale advantage of a larger company.

Market Dynamics of Global Skin graft Market:

Drivers

Rise in the cases of risk factors such as accidents, skin infections such as necrotizing fasciitis or purpura fulminans, burns, cancer, surgeries and others. According to WHO, burns are a leading cause of public health issue causing approximately 265000 deaths annually. The global burn care market size is approximately USD 1.5 billion in 2016.

Technical advancements in surgical instruments such as development of electrical dermatome and drum-type dermatome which has resulted in greater accuracy and control.

Growing occupational hazards such as electricity, high temperatures, machinery and others

Restraints

Complications such as infection, pain and hospital stay

High cost of treatment

Lack of healthcare infrastructure in developing regions

Rejection and immune reactions which can be fatal

Segments of Global Skin graft Market:

The global skin graft market report is segmented on the basis of graft type, graft thickness and applications. Graft type - autologous, isogeneic, allogeneic, xenogeneic and prosthetic.

Graft thickness - split-thickness, full-thickness and composite graft.

Applications - extensive wound, burns, extensive skin loss due to infection, skin cancers and others. Equipment - dermatome (knives dermatomes, drum dermatomes, electric dermatomes, air dermatomes), general surgical instruments, consumables and others.

End users - hospitals and clinics, academic and research and others.

Regional analysis of Global Skin graft Market:

US accounts for the maximum market share due to faster market uptake of new technology, favourable reimbursement scenario and greater expenditure on healthcare. Europe is the second largest market due to large disposable income and rising awareness which is led by France and Germany. Asia Pacific region is expected to generate fastest growth and is estimated to be led by China and India. However Japan has the largest market share in the region as of 2016. Asia Pacific also has a

The Middle East & Africa market is led by the gulf nations particularly Saudi Arabia and UAE. The regions of Africa are expected to witness a moderate growth due to poor economic and political conditions and poor healthcare penetration.

About Market Research Future:

Market Research Future (MRFR) is a global market research company that takes pride in its services, offering a complete and accurate analysis with regard to diverse markets and consumers worldwide. Market Research Future has the distinguished objective of providing the optimal quality research and granular research to clients. Our market research studies by products, services, technologies, applications, end users, and market players for global, regional, and country level market segments, enable our clients to see more, know more, and do more, which help answer your most important questions.

Contact Us:

Market Research Future (Part of Wantstats Research and Media Private Limited)

99 Hudson Street, 5Th Floor

New York, NY 10013

United States of America

+1 628 258 0071 (US)

+44 2035 002 764 (UK)

Email: sales@marketresearchfuture.com

Website: https://www.marketresearchfuture.com

[jorvik-aita]

warning this ones long: I didn’t realize how long it was when i wrote it.

POV: Big Bonny, formally: Bonnibel Blair.

AITA for creating robots that are half machine, half human for an evil company? 

For context, I was at this job for months. They company approached me offering me a Job as an “innovated organic machine operator.” At the time I wasn’t sure what that meant. 

However, it must have been something important for I hadn’t heard of the company before. They wanted me to keep things hush-hush reasoning that they were to quote “working on top-secret projects involving the most advanced science and technology that have yet to hit the Jorvegian market.” 

Which sounded like a dream come true. Since my true passion is pushing the boundaries of technology and science. 

However, once I got there things started going horribly wrong. It started off small, first with the workers there seemed to hate their jobs. All were gloomy, nonchalant at best. One of the workers even said that the novelty of the place wear’s off after a while. Only now do I see what he meant by that. 

Then, the job seemed to at first not be what I expected it to be. For after a few weeks there I only hand-cleaned barbed wire fences and polish bolts in the wall. I almost quit then and I should have to be honest. However then, I met the man in charge. That was a mistake. 

The man in charge managed to convince me to stay and to quote “serve Dark Core to the best of your abilities.” I of course blurted out yes before he had finished speaking for he had offered me my true task. And I was so pleased to get to actually follow my passion that overrode any unhappiness. 

Then my True job was reveled. That was to create robots that were part man, part machine. They would be a husk of a human, no emotions, no memories, merely some cogs and wheels with some silicone skins grafted over them. And I then started using dark science, cloning, and secrets only Dark Core knew, that I dare not speak out loud. Heaven forbid write them down.

A few months passed after that event. I sorely regret it. I spent those months buried in my work. Created clones with no emotions, and no thoughts. Their only purpose was to see Dark Core succeed. And to boot their machinery makes them unnaturally strong. I gave them googles to cover their lifeless eyes, and gloves to cover their robotic hands. 

For a while it was only mildly unsettling to create something so life-like that isn’t alive at all. But the thrill of pushing the boundaries of science was far too exciting to abandon. That was until I reached my breaking point. 

That night of my breaking point, I could not ignore any longer how that the more clones I created the more the human workers disappeared. And after a while it was just me and the clones. No humans resided on that rig any longer. I decided to confront my boss in the morning.

However, as I was sleeping in my bunk after a long hard days work, I awoke to fateful nosies. I heard the cries of horses, and cackles of humans ringing throughout the metallic shell of the rig. And the curiosity got the best of me and I snuck out of my bunk determined to find answers. But as they say curiosity killed the cat and it could have killed me in that instance. For what I saw changed my life forever. 

My boss, and four shadowy figures were standing in the middle of a platform. There, towering over them, was a deeply horrible, terrifying sight. I saw there, a portal to an another place, it was swirling with darkness. It was emitting the cries of horses I heard from my bunk. These cries now sounded even more horrible than they did from my bunk almost as if the poor intelligent caring animals were being tortured. My heart cried out for them.

However, before I could processes anything, they turned around, spotting me with ridiculous accuracy. Spotting me like an eagle does with a mouse. My instincts came over me and I fled and grabbed the nearest rickety rowboat I could find. I rowed with such ferocity you would think my ass was on fire. 

I only turned around for a glimpse to see if they were watching. And they were. Thats the last I saw of my boss and the four shadowy figures; them standing at the edge of the platform; watching me row away. I can only conclude that my boss knew what I saw, he knew it was me. And from then on my life has been in danger. 

Once, I got back to the beaches of Jorvik I could swear I could still feel their eyes on me. So I escaped further inland. Since then I have gone into hiding.  I live now in a sleepy small town. I dare not name where for fear they will come get me. Yet some small part of me thinks they let me live, they let me reside here. Maybe they know I won’t dare tell the authorities?

In the end, this sleepy village is where I made my home, doing my best to blend into regular life. I have done my best to process everything that happened. And to process that I was contributing to the evil intentions of Dark Core. 

I’ve been trying to make amends, and bring as many inventions to Jorvik for the better of the island. I first started with making a clone, with emotions, thoughts, and feelings. I called her Little Bonny. And sent her out into the world to live a life like everyone else. Someday she shall be called Big Bonny like me. She didn’t move far from me and I visit her whenever I can. She’s a Witch now in Moorland, helping the youth of Jorvik. I’m proud of her.

Today, I have long been living my fresh start at life. Filling it with the normalcy of mundane life, and not an evil corporation in sight. 

It does feel good to get all of this off my chest. But I can’t help but feel, AITA, for being young and stupid, and creating those clones that contributed to the evil Dark Core has done? 

[sydmarch]

bcus of hannah's doctor bringing up the celebrity skin graft thing + the celebrity steak market i've always wondered how likely it is that there's an industry of lab grown celebrity organs that people get transplanted for fun