#Sequencing

[cbirt]

In order to establish standardized high-throughput whole-genome sequencing (WGS) for patients with cancer and rare diseases, the UK Government launched the groundbreaking 100,000 Genomes Project within the National Health Service (NHS) in England. This was accomplished through the use of an automated bioinformatics pipeline accredited by the International Organisation for Standardisation. Operating in conjunction with NHS England, Genomics England examined WGS data from 13,880 solid tumors representing 33 different cancer types, fusing genetic information with actual treatment and outcome data in a secure research environment. 

WGS and longitudinal life course clinical data were linked, enabling the evaluation of treatment results for patients categorized by pangenomic markers. The results of this study show how useful it is to connect genomic and practical clinical data in order to do survival analysis, locate cancer genes that influence prognosis, and deepen our knowledge of how cancer genomics affects patient outcomes.

Using an automated bioinformatics pipeline accredited by the International Organisation for Standardisation, the 100,000 Genomes Project was a ground-breaking UK Government initiative implemented within the National Health Service (NHS) in England with the goal of establishing standardized high-throughput whole-genome sequencing (WGS) for patients with cancer and rare diseases.

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[grrlmusic]

C2H4

[everythingaboutbiotech]

Common uses of bioinformatics

💡Sequence analysis Analyzing DNA and protein sequences to identify genes, regulatory regions & mutations.

💡Gene expression Analyzing RNA expression data from experiments like microarrays or RNA-seq to understand gene regulation.

💡Phylogenetics Constructing evolutionary relationships between organisms based on genetic data and genomic comparisons.

💡Molecular modeling Predicting protein structure and docking drugs to proteins using computational modeling and simulation.

💡Databases & Data mining Developing databases like GenBank to store biological data and mining it to find patterns.

💡Genomics Studying entire genomes, including sequencing and assembling genomes as well as identifying genes and genomic variations.

Follow @everythingaboutbiotech for useful posts.

[jewishdragon]

When a computer slows down bc its processing a shit ton of sequencing data i say "gotta be patient, the computer is doing a big thinkie"

[yaoifortresstwo]

hi guys (covered in blood)

[pathologylab]

HPV awareness and education is the key for preventing various HPV-related cancers. One of them is cervical cancer, a disease that kills thousands of women every year. Being a virus-borne infection, HPV infections are communicable that can travel among people through skin-to-skin contact (sexual intercourse). There are over 100 strains of HPV, more than 40 of which are passed through sexual contact and can affect your genitals, mouth, or throat. Genes2Me HPV-Q Comprehensive Real-Time PCR kit screens for the presence/absence of HPV in genotypes. Take the test today to determine your risk of HPV.

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To know more visit https://t2m.io/HPVKits

[yaoifortresstwo]

:/

Gordon Ramsey fursona reveal!

[and-corn]

are evil dragons really evil, or are they just vitamin D deficient?

(pt 2)

[miikpal]

24 ribs

[beif0ngs]

I had a different name back then, you know. Powder. You kind of remind me of her.

[cbirt]

Suppose there was a library where the whole instruction manual for every living organism on Earth could be found. It’s not science fiction, but projects such as “Indexing All Life’s Known Biological Sequences” are designed to try and accomplish this. In this case, the instructions refer to DNA and protein sequences that constitute the blueprints of life. Decoding these sequences is necessary to understand how organisms function, evolve, and relate to each other. However, searching and analyzing these sequences has become difficult due to increased biological data being generated. This is where MetaGraph comes in – a powerful new tool that functions like Google for DNA, which was developed by researchers to tackle the problem of managing massive biological sequence datasets.

Our genetic information is written using nucleotides, which are essentially building blocks of RNA and DNA. Each living thing has its own set of these nucleotides arranged in an elaborate labyrinthine codebook. MetaGraph uses “De Bruijn graphs,” a smart strategy for representing these sequences efficiently. Think about it like a detailed map where each part represents a short sequence (called k-mer) while connections between sections show overlap between those k-mers.

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[everythingaboutbiotech]

Looking to enhance your bioinformatics skills and take your research to the next level? Look no further than justbio - your one-stop-shop for all things bioinformatics!

[moondvncer]

MY HEART JUST MELTED OH MY GOD

🥺🥹😭🤧🥹😭

[yaoifortresstwo]

sigh.

there was also this which i am. very not sure qualifies as harassment

[pathologylab]

As we approach #MEDICA 2024, we’re thrilled to showcase our latest innovations in #diagnostics! Join us in Düsseldorf from November 11-14 at booth #H1/F23 to explore our advanced solutions in point-of-care #testing, #NGS clinical panels, Real-Time #PCR, and nucleic acid extraction solutions. 

Don’t miss the chance to discuss the future of diagnostic #healthcare with our team.

🤝 : Dusseldorf, Germany

📅 : November 11–14, 2024

🏪 : H1/F23

🌍 : https://www.genes2me.com/upcoming-events

Scan the QR code to book your meeting slots, or click here!

#MEDICA2024 #HealthcareInnovation #MolecularDiagnostics #G2M #conference #exhibition #nucleicacid #nucleic #solutions #rtpcr #Dusseldorf #nextgenerationsequencing #sequencing

[bio-basic-inc]

Dive into the future of molecular biology with Next-Gen Sequencing (NGS)! Revolutionize your research with this cutting-edge technology that unlocks the secrets of entire genomes in record time. 

Say “goodbye” to traditional sequencing methods and hello to a world of possibilities! 

At Bio Basic, we're at the forefront of NGS innovation, offering rigorously tested products that guarantee safety and compliance with industry standards. With prompt delivery and seamless experiments, your journey to discovery just got smoother. 

Inquire more about our NGS services today at sequencing@biobasic.com

Or, browse https://www.biobasic.com/dna-next-gen/ for further details.