#ScienceNews

[cbirt]

Large-scale gene expression data is used by Geneformer and scGPT models to build fundamental single-cell biology models. These models implicitly learn gene and cellular activities from millions of cell expression profiles, necessitating labor-intensive training and considerable data curation. Here, researchers from Stanford University use gene embeddings from the literature leveraging ChatGPT to investigate a much easier solution. In order to create gene embeddings, GenePT uses the GPT-3.5 and the NCBI text descriptions of specific genes. 

GenePT is an effective technique for creating single-cell embeddings by averaging gene embeddings according to the expression level of each gene. It performs on par with or better than Geneformer and other models, and it is user-friendly and efficient. GenePT generates sentence embeddings for every cell by sorting gene names according to expression level. It shows that a straightforward and efficient route for biological foundation models is the large language model embedding of literature.

The foundation models Geneformer and scGPT  are made to learn gene and cell embeddings for further investigations. Using a deep learning architecture, these models link input genes and cells to a high-dimensional embedding vector and collect large datasets of single-cell gene expression for pretraining. A small amount of task-specific data can be used to refine the model and improve its predictive power for downstream tasks.

Continue Reading

[manifestisnow]

Anything is possible in the Quantum field Using Affirmations can help you get in flow with it.

Love and Light Manifestisnow.

[whatshappeningintheworlds-blog]

Officials confirmed on Monday that the metal item that crashed from the sky, tearing through the roof of a Naples, Florida, home last month and lodged in a family's wall, was part of the debris from a trash pallet NASA launched into space three years prior.

[sassylightcycle]

read Full article click

[neosciencehub]

"Patients and Research are My Greatest Teachers in Medicine"

"Patients and Research are My Greatest Teachers in Medicine" @neosciencehub #neosciencehub #science #HIV #AIDS #HIVAIDS #treatment #healthcare #pharma #physicians #research #scientists #tuberculosis #NSH

Dr.Yanamadala Muralikrishna: A Pioneer in HIV Treatment & Global Health Innovation In the realm of infectious diseases, few figures stand out as prominently as Dr.YanamadalaMuralikrishna. A trailblazer in HIV treatment, Dr.Muralikrishna has dedicated his career to transforming the management of HIV/AIDS, particularly in resource-limited settings like India.As the first HIV physician in the…

[shuttech]

New Earth-Like Planet Discovered: A Potential Future for Humanity?

Astronomers have made an exciting discovery with the identification of a new Earth-like planet located in the habitable zone of its star. This planet, which shares key characteristics with Earth, such as a potential atmosphere and suitable temperatures for liquid water, has sparked conversations about the possibility of it becoming a future home for humanity.

For More Info: https://shuttech.com/uncategorized/new-earth-like-planet-discovered-a-potential-future-for-humanity/

[dropsofsciencenews]

IUCN Red Lists 2024: Growing Emergency for Species at Risk, Now Including the European Hedgehog

The IUCN Red Lists of Threatened Species represent an inventory of the global conservation status and extinction risk of biological species. Based on threat levels, species are categorized as: Not Evaluated, Data Deficient, Least Concern, Near Threatened, Vulnerable, Endangered, Critically Endangered, Extinct in the Wild, Extinct. A new update to these lists was published on October 28, now including 166,061 species, 46,337 of which are threatened with extinction. The global trend shows a severe decline across many species groups.

Among the most critical situations is the decline of migratory shorebird populations worldwide, with 16 species reclassified into higher threat categories. For example, the Grey Plover (Pluvialis squatarola) and Curlew Sandpiper (Calidris ferruginea), whose populations have decreased by 30%, were reclassified as Vulnerable and Near Threatened, respectively.

Other animal species are now classified as "Critically Endangered," meaning extinction could be imminent if their decline continues. Among these, the Manus Island spiny rat (Rattus detentus), last seen in 2016 in Papua New Guinea's Bismarck Archipelago, is threatened by invasive predators and habitat degradation. The Nyanga rinkhals (Hemachatus nyangensis), a snake in Zimbabwe's Eastern Highlands, faces habitat transformation and invasive plants, with no sightings since 1988. The Vietnam pheasant (Lophura edwardsi), not seen in the wild since 2000, suffers from deforestation and hunting, and ex-situ conservation programs are underway.

Corals are also struggling for survival: 44% of hard coral species are threatened, an 11% increase since 2008. Among the most affected is the Acropora genus, with 99 out of 150 species now at risk.

Another distressing case is the Western European hedgehog (Erinaceus europaeus), now classified as Near Threatened. Its population has plummeted in the last decade due to human pressure, particularly from agricultural intensification and urban development.

For the first time, most of the world’s tree species have been included in the Red List: at least 16,425 out of 47,282 species assessed, or over a third, are at risk of extinction. Island species, in particular, face severe threats due to urban development, pests, diseases, and invasive species. Trees are essential to ecosystems; their loss would compromise the survival of thousands of other species, destabilize carbon, water, and nutrient cycles, and disrupt soil formation and climate regulation.

This update of the IUCN Red Lists is not only a barometer of global biodiversity but also emphasizes the urgent need for coordinated conservation actions to prevent our planet from losing precious elements of its biological wealth.

See you soon and Good Science!

source

pic by Jörg Hempel

[futuretechnerd]

"🌍🌪️ The Future of Earth is in Our Hands!"

"According to scientists, 70% of Earth's population will face extreme weather within the next 20 years. If we don’t act, rising temperatures, superstorms, and wildfires will become our new normal. The question is: What are we doing to prepare? #ClimateChange #TechToTheRescue #sustainablefuture

#FutureTech #ClimateAction #SaveOurPlanet #Sustainability #TechForGood #ClimateScience #WeatherPrediction #TechNerd #futuretechnerd

[radhemishra]

"Groundbreaking Discovery: Unveiling the Secret to Lifelong Memories!

After years of dedicated research, brain scientists have made a revolutionary breakthrough, identifying the elusive 'memory glue' that enables memories to stick for a lifetime! This remarkable finding has significant implications for understanding human memory and developing innovative treatments for memory-related disorders.

The 'Memory Glue' Protein: NeuroLock

The discovered protein, dubbed "NeuroLock," plays a crucial role in:

1. Strengthening neural connections: NeuroLock fortifies the bonds between brain cells, ensuring memories are securely stored.

2. Consolidating memories: This protein facilitates the transfer of information from short-term to long-term memory, making recollections last a lifetime.

3. Retrieving memories: NeuroLock enables precise and clear memory recall, allowing us to relive moments with vivid detail."

Implications and Future Directions:

1. Memory Enhancement: Unlocking human memory potential with NeuroLock-based therapies.

2. Treating Memory Disorders: Revolutionary treatments for Alzheimer's, dementia, and other memory-related conditions.

3. Understanding Brain Function: Gaining insight into the intricate mechanisms of human memory and cognition.

Join the conversation and share your thoughts on this monumental discovery!

[horizonpulse05]

Don’t miss the stunning nova explosion lighting up the night sky! Our latest blog post explores this awe-inspiring cosmic event. Learn what a nova is and why this one is creating a buzz. Click the link to read more!

[jameswebb-discoveries]

James Webb Space Telescope Uncovers New Mysteries of the Crab Nebula

NASA’s James Webb Space Telescope has unveiled groundbreaking details about the Crab Nebula! This iconic supernova remnant, observed in unprecedented detail, challenges previous theories about its origins. JWST’s advanced instruments revealed intricate structures and compositions, offering fresh insights into the enigmatic nebula. Dive into the mysteries of space with this latest discovery!

🔭🚀 Read more: https://www.jameswebbdiscovery.com/discoveries/james-webb-space-telescope-uncovers-new-mysteries-of-the-crab-nebula

#NASA #JamesWebb #CrabNebula #SpaceDiscovery #Astronomy #Supernova #SpaceExploration #Astrophysics #ScienceNews

[cbirt]

Most SARS-CoV-2 patients experience anosmia, or a loss of smell, which can linger for months after recovery. According to olfactory epithelium samples taken from 24 biopsies, T cell-mediated inflammation continues in the olfactory epithelium even after SARS-CoV-2 has been removed from the tissue, indicating a mechanism for long-term post-COVID-19 smell loss.

The severe acute respiratory syndrome coronavirus 2 is thought to harm the olfactory epithelium, a specialized tissue involved in smell sense that runs along the top of the nasal cavity (SARS-CoV-2). The olfactory epithelium comprises three key components: odor-detecting olfactory receptor cells, a sustentacular cell layer for support, and basal stem cells that replenish the cells continually.

Continue Reading

[vitrinanorte]

Chile es elegido para albergar la reunión de astronomía más importante del mundo en 2030

Nuestro país se impuso por sobre las otras tres candidaturas: España, Australia e India, para organizar la reunión que se realizará en Santiago y que recibirá a más de 3 mil visitantes.

La propuesta fue liderada a nivel internacional por la Sociedad Chilena de Astronomía con el apoyo del Gobierno de Chile y el Congreso, entre otros.

La Asamblea General de la Unión Astronómica Internacional (UAI/IAU) se realizará en Santiago en 2030. Así fue anunciado hoy en Ciudad del Cabo, Sudáfrica, ciudad que acogió a este encuentro en su versión 2024, que termina hoy. La postulación de Santiago como futura sede fue encabezada por la Sociedad Chilena de Astronomía, SOCHIAS, y sumó múltiples apoyos durante 2023 y 2024.

El Presidente Gabriel Boric declaró: “Desde Chile levantamos nuestra candidatura para poder albergar en nuestra patria esta discusión, esta instancia, este debate, porque nos sentimos privilegiados de los cielos que tenemos. Chile observa al mundo y desde Chile se observa al universo. Y estamos muy orgullosos de eso y cuidando también nuestros cielos. Hoy día para poder albergar esta iniciativa tenemos el respaldo del gobierno, del Congreso, de la Gobernación Regional de la Región Metropolitana, de otras gobernaciones regionales y por cierto también de las más de 20 universidades que realizan investigación astronómica en nuestro país. Para esa fecha el 55% de la observación astronómica mundial se va a realizar desde suelo chileno. Por eso será para nosotros un orgullo poder acoger a todos los astrónomos que vengan, que conozcan las bondades de nuestra patria y desde aquí mirar al infinito”.

Por su parte, la ministra de Ciencia Aisén Etcheverry dijo: “Estamos muy orgullosos por lo que significa este reconocimiento para nuestro país. Tenemos mucho trabajo por delante, estamos seguros que esta cumbre que se hará en el 2030 nos va a permitir seguir consolidando la idea de que Chile es un país de ciencia, donde el desarrollo científico se basa en la colaboración internacional y donde tenemos a grandes investigadores e investigadoras que nos ayudan cada día a sorprendernos con nuevos conocimientos en torno al origen del universo, a explorar la posibilidad de vida en otros planetas y tantas otras preguntas fundamentales. Desarrollar en Chile esta cumbre astronómica viene a coronar esfuerzos importantísimos que hemos hecho por avanzar, a través de una política de Estado, gobierno a gobierno, en capacidades astronómicas únicas en el mundo y con un liderazgo reconocido a nivel internacional”.

La Sociedad Chilena de Astronomía, SOCHIAS, principal impulsora de la postulación y presidida por el astrónomo Bruno Dias, declaró: “Este gran logro es el fruto de meses de arduo trabajo y esfuerzo conjunto de SOCHIAS, el Ministerio de Relaciones Exteriores y el Ministerio de Ciencia, Tecnología, Conocimiento e Innovación del Gobierno de Chile, el Comité Organizador Nacional, Metropolitano, Sernatur, Imagen de Chile. Así también agradecemos a las Universidades chilenas, centros basales, Institutos y Núcleos Milenio, observatorios internacionales, Senado y Cámara de Diputados, Municipalidad de Vitacura, HL Producciones, Sky Airlines, astrónomos y astrónomas nacionales, además de apoyo externo de la comunidad astronómica Latinoamericana, premios Nobel, Simons Foundation, entre otros, quienes unieron fuerzas para presentar una candidatura sólida y convincente”.

Ezequiel Treister, director del Centro de Astrofísica y Tecnologías Afines, CATA, también celebró la noticia: “Esto viene a reafirmar lo que sabemos: que Chile es realmente el epicentro de la astronomía mundial. Es una satisfacción haber sido elegidos en una competencia muy dura, con países muy desarrollados, con muchos recursos. Y es una oportunidad, obviamente, para mostrar la investigación en astronomía en sí, pero también para todas las ciencias relacionadas, para el turismo astronómico, para desarrollar y mostrar el desarrollo que tiene la industria en Chile y las potencialidades que tenemos. Vamos a tener gente de todos los observatorios del mundo, así que, sin duda, es una gran oportunidad”.

¿Qué es la IAU?

La Asamblea General de la Unión Astronómica Internacional es la reunión internacional de astronomía más importante del mundo. Se realiza cada tres años desde 1922 y reúne a más de 3 mil participantes. Durante dos semanas se discute el futuro de la astronomía, los nuevos instrumentos y telescopios -disponibles y por diseñar- y las colaboraciones necesarias para avanzar. Hay sesiones especiales dedicadas a los últimos descubrimientos, jóvenes en astronomía, y difusión, charlas públicas, eventos científicos, culturales y turísticos.

“Este gran evento le dará a Chile la oportunidad de destacar la importancia de la investigación astronómica en nuestro país, donde se realiza más de la mitad de la observación de los cielos del mundo, y de compartir el conocimiento de Chile en esta materia. Hacemos el compromiso de organizar un encuentro inolvidable que inspire a astrónomas y astrónomos, y a todas aquellas personas que miran al cielo con curiosidad”, dijo el presidente de SOCHIAS, Bruno Dias.

[outer-space-youtube]

AI Lies! 

What to learn from this video?  1: The Billionaires pushing AI fears are trying to get richer via investments to stop AI…   2: The Nuclear fears were pushed to cause global warming to accrue faster to drive the fear of the end of the world.   3: Who controls what you fear controls your vote..?   Who are we to blame but the Illuminated Ones, whom we know as the “Illuminati”? No, I am not a…

[neosciencehub]

The Evolution of HIV Treatment: Dr. Yanamadala Muralikrishna’s Pioneering Two-Drug Therapy

The Evolution of HIV Treatment: Dr. Yanamadala Muralikrishna’s Pioneering Two-Drug Therapy @neosciencehub #neosciencehub #science #TwoDrugTherapy #HIVTreatment #HIV #AIDS #research #drugs #Medical #journal #GlobalHealth #health #Pharma #NSH

In the November 2024 edition of The National Medical Journal of India, Dr. Yanamadala Muralikrishna’s remarkable contributions to HIV treatment were highlighted, particularly his advocacy for the two-drug regimen that has transformed the landscape of HIV management globally. In a review on his book, “HIV-AIDS in India and Developing Countries”, Manish Soneja, Department of Medicine, AIIMS, said:…