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Bitcoin and Altcoins Update: Market Movements and Key Developments
The cryptocurrency market has experienced some intriguing shifts recently, with Bitcoin and various altcoins demonstrating varying levels of performance. Here’s a detailed overview of the latest market movements and notable developments.
Bitcoin: A Modest Decline with Strong Weekly Gains
Bitcoin, the leading cryptocurrency, has seen a slight decline of 0.9%, bringing its current price to $64,166.3. Despite this recent dip, Bitcoin has shown significant strength over the past week, trading up by 8.5%. This positive weekly performance highlights Bitcoin's resilience and continued appeal as an investment asset, even amidst short-term fluctuations.
Ether: A Small Drop Amid Anticipated ETF Approval
Ether has fallen by 0.2%, settling at $3,444.58. The drop comes as market participants await potential regulatory news. Recent reports suggest that the Securities and Exchange Commission (SEC) might approve a spot Ether ETF as early as next week. Such approval could have substantial implications for Ether's market dynamics, potentially driving up its value as institutional investment opportunities become more accessible.
SOL: Noteworthy Surge with ETF News
In contrast to Ether’s slight decline, Solana (SOL) has surged by 3.8%. This increase follows reports indicating that a spot SOL ETF is also in the pipeline. The anticipated approval of such an ETF could enhance Solana's visibility and attract new investment, contributing to its recent upward momentum.
ADA and XRP: Downturns Amid Market Volatility
Both Cardano (ADA) and Ripple (XRP) have experienced notable declines. ADA fell by 2.3%, while XRP saw a more substantial drop of 4.7%. These downturns reflect broader market volatility and may be influenced by various factors, including regulatory uncertainties and shifting investor sentiments.
Meme Tokens: DOGE and SHIB Face Declines
Among meme tokens, Dogecoin (DOGE) and Shiba Inu (SHIB) have also faced declines. DOGE fell by 1.1%, while SHIB saw a more significant slide of 6.2%. The fluctuations in these tokens underscore the volatility often seen in the meme coin sector, where price movements can be heavily influenced by social media trends and speculative trading.
Conclusion
The cryptocurrency market continues to demonstrate its dynamic nature, with Bitcoin maintaining a strong weekly performance despite recent declines. Ether’s minor drop is tempered by the potential approval of a spot ETF, which could bolster its market position. Meanwhile, Solana’s recent rise reflects optimism around its forthcoming ETF, while ADA and XRP, along with meme tokens like DOGE and SHIB, face varying degrees of market pressure. As always, staying informed about these developments is crucial for investors navigating the ever-evolving crypto landscape.
#Cryptocurrency market#Bitcoin performance#Ether ETF approval#Solana surge#Cardano decline#Ripple market volatility#Meme tokens#Dogecoin decline#Shiba Inu price drop#Crypto market trends#Investment opportunities#Regulatory news#Market analysis#Crypto market shifts#Institutional investment in crypto#SEC crypto regulations#Crypto market dynamics#Crypto investment strategies#Altcoin performance#Cryptocurrency news
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#medical device#import license medical devices#Class C & D medical device import license#medical device regulation#operon strategist#what is the right time to apply for import license for Class C & D medical device in india#class C & D medical device import in india#new timeline for class c & d medical device in india#Class C & D medical devices#update for medical device import#CDSCO guidlines#trending news for medical devices#trending news#CDSCO News#regulatory news
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Considering everything going on with the missing submersible full of rich people who wanted to visit the titanic for 250,000 dollars a pop, I thought it would be a good time to link this Sunday morning segment that talks about the company and the submersible:
youtube
Namely, 2:40-4:00 where they specifically state how it's not approved by any regulatory authority in the liability agreement and it's operated via an Xbox controller or something among the many other erm, interesting design choices (like ceiling handles from camping world)
So you know, do with this info what you will
#personally I would not get in a small tube whose design is not certified by any relevant regulatory authority for a lot of money#I'd say it's akin to paying a million dollars to the monopoly man to get to the top of mount everest via large catapult#titanic#titanic submarine#submarine#tumblr news#submersible#Youtube
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This is an important article by Linda Greenhouse, writing in The New York Times. Therefore, the link above is a gift 🎁 link, so anyone can read the article, even if they don't subscribe to the Times.
Below are some excerpts from the article:
To understand today’s Supreme Court, to see it whole, demands a longer timeline. To show why, I offer a thought experiment. Suppose a modern Rip Van Winkle went to sleep in September 2005 and didn’t wake up until last week. Such a person would awaken in a profoundly different constitutional world, a world transformed, term by term and case by case, at the Supreme Court’s hand. To appreciate that transformation’s full dimension, consider the robust conservative wish list that greeted the new chief justice 18 years ago: Overturn Roe v. Wade. Reinterpret the Second Amendment to make private gun ownership a constitutional right. Eliminate race-based affirmative action in university admissions. Elevate the place of religion across the legal landscape. Curb the regulatory power of federal agencies. [...} That was how the world looked on Sept. 29, 2005, when Chief Justice Roberts took the oath of office, less than a month after the death of his mentor, Chief Justice Rehnquist. And this year? By the time the sun set on June 30, the term’s final day, every goal on the conservative wish list had been achieved. All of it. To miss that remarkable fact is to miss the story of the Roberts court. It’s worth reviewing how the court accomplished each of the goals. It deployed a variety of tools and strategies. Precedents that stood in the way were either repudiated outright, as the Dobbs v. Jackson Women’s Health Organization decision did last year to Roe v. Wade and Planned Parenthood v. Casey, or were simply rendered irrelevant — abandoned, in the odd euphemism the court has taken to using. In its affirmative action decision declaring race-conscious university admissions to be unconstitutional, Chief Justice Roberts’s majority opinion did not overturn the 2003 Grutter decision explicitly. But Justice Thomas was certainly correct in his concurring opinion when he wrote that it was “clear that Grutter is, for all intents and purposes, overruled.” Likewise, the court has not formally overruled its Chevron decision. Its administrative-law decisions have just stopped citing that 1984 precedent as authority. The justices have simply replaced Chevron’s rule of judicial deference with its polar opposite, a new rule that goes by the name of the major questions doctrine. Under this doctrine, the court will uphold an agency’s regulatory action on a major question only if Congress’s grant of authority to the agency on the particular issue was explicit. Deference, in other words, is now the exception, no longer the rule. But how to tell a major question from an ordinary one? No surprise there: The court itself will decide. [...] My focus here on what these past 18 years have achieved has been on the court itself. But of course, the Supreme Court doesn’t stand alone. Powerful social and political movements swirl around it, carefully cultivating cases and serving them up to justices who themselves were propelled to their positions of great power by those movements. The Supreme Court now is this country’s ultimate political prize. That may not be apparent on a day-to-day or even a term-by-term basis. But from the perspective of 18 years, that conclusion is as unavoidable as it is frightening.
#us supreme court#18 years of the roberts' court#chief justice john roberts#affirmative action#second amendment#separation of church and state#regulatory agencies#women's reproductive health#linda greenhouse#the new york times#gift link
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Maryland’s top utility regulator was watching the news one February morning when a headline blindsided him: Two suspects with neo-Nazi ties had been charged with plotting to take down Baltimore’s power grid.
Jason Stanek, the then-chair of the state’s Public Service Commission, said Maryland regulators were “caught flat-footed,” not hearing a word from law enforcement before the news broke — or in the months afterward. Federal prosecutors have alleged the defendants were driven by “racially motivated hatred” to try to cut power to hundreds of thousands of people in the state’s largest city, which has a predominantly Black population.
The FBI declined to comment on its communications with the Maryland commission. But Stanek’s experience is not uncommon.
A POLITICO analysis of federal data and interviews with a dozen security, extremism and electricity experts revealed that despite a record surge in attacks on the grid nationwide, communication gaps between law enforcement and state and federal regulators have left many officials largely in the dark about the extent of the threat. They have also hampered efforts to safeguard the power network.
Adding to the difficulties, no single agency keeps a complete record of all such incidents. But the attacks they know about have regulators and other power experts alarmed:
— Utilities reported 60 incidents they characterized as physical threats or attacks on major grid infrastructure, in addition to two cyberattacks, during the first three months of 2023 alone, according to mandatory disclosures they filed with the Department of Energy. That’s more than double the number from the same period last year. DOE has not yet released data past March.
— Nine of this year’s attacks led to power disruptions, the DOE records indicate.
— The U.S. is on pace to meet or exceed last year’s record of 164 major cyber and physical attacks.
— And additional analyses imply that the true number of incidents for both 2022 and 2023 is probably even higher. POLITICO’s analysis found several incidents that utilities had reported to homeland security officials but did not show up in DOE data.
According to a report on grid security compiled by a power industry cyber clearinghouse, obtained by POLITICO, a total of 1,665 security incidents involving the U.S. and Canadian power grids occurred last year. That count included 60 incidents that led to outages, 71% more than in 2021.
While that report does not break down how many of those incidents occurred in which country, the U.S. has a significantly larger grid, serving 145 million homes and businesses, with nearly seven times Canada’s power-generating capacity.
Law enforcement officials have blamed much of the rise in grid assaults on white nationalist and far-right extremists, who they say are using online forums to spread tactical advice on how to shut down the power supply.
Concerns about the attacks have continued in recent months, with incidents including a June indictment of an Idaho man accused of shooting two hydroelectric stations in the state.
But law enforcement officers investigating alleged plots against the grid don’t necessarily alert the Energy Department or other regulatory bodies.
“We have no idea” how many attacks on the grid are occurring, said Jon Wellinghoff, a former chair of the Federal Energy Regulatory Commission, which regulates the U.S. electric grid. “It looks like they’re escalating if you look at the data. But if you don’t have enough data, you can’t discern patterns and proactively work to stop these things from happening.”
Wellinghoff was FERC’s chair when an unknown sniper attacked a Pacific Gas and Electric substation in San Jose, Calif., in 2013 — an incident regulators have described as a “wake-up call” on the electricity supply’s vulnerability to sabotage.
Last year’s record number of physical and cyber disruptions to the U.S. power system included several incidents that captured public attention, such as a December shooting attack against two North Carolina substations that left 45,000 people without power for four days. The state’s medical examiner has blamed the attack for the death of an 87-year-old woman who died after her oxygen machine failed, ruling it a homicide. Nobody has been charged.
“There is no doubt there’s been an uptick over the last three years in the amount of incidents and also the severity of the incidents,” said Manny Cancel, senior vice president at the North American Electric Reliability Corp., the nonprofit body in charge of setting reliability standards for the bulk power system. He is also CEO of its Electricity Information Sharing and Analysis Center, which gathers and analyzes data from power companies.
Cancel said NERC has “seen two pretty substantial increases” in incidents coinciding with the 2020 and 2022 election cycles.
Grid attacks that led to power outages increased 71% from 2021 to 2022, totaling 55 incidents in 2022, according to a NERC briefing to utilities that POLITICO obtained. That increase was primarily due to a rise in gunfire assaults against critical infrastructure.
The largest outage reported from a physical attack early this year — which occurred in March in Clark County, Nev. — affected more than 11,000 people, according to DOE data.
But the state Public Utilities Commission was not aware of any outage due to an attack occurring that day, spokesperson Peter Kostes told POLITICO by email. That’s even though state regulations require utilities to contact the commission within four hours of a significant outage.
The state’s largest utility, NV Energy, said in a statement that it had reported the incident to local law enforcement “as soon as we learned about this incident ... so we can continue to increase our resilience against ongoing threats to the energy industry.” A spokesperson for the utility did not respond to multiple requests for comment on whether it had informed the commission.
Federal regulations also require utilities to report cyber or physical attacks to DOE, including physical attacks that cause “major interruptions or impacts” to operations.
They must also tell the department about disruptions from weather or other causes that meet certain criteria, such as those that cut off service to more than 50,000 customers for at least an hour, an uncontrolled loss of more than 200 megawatts of power, or a utility voluntarily shutting more than 100 megawatts, according to an Energy Department spokesperson. The spokesperson provided the information on the condition that they not be identified by name.
The Energy Department’s records don’t include at least seven reported physical assaults last year and this year that the Department of Homeland Security and the affected utilities said caused substantive economic damage or cut off power to thousands of customers. POLITICO found these incidents by cross-checking the department’s data against warnings issued by DHS and the FBI’s Office of the Private Sector.
DOE said the incidents may not meet its reporting thresholds.
Several of the incidents missing from DOE’s data involved clear physical attacks, based on other agencies’ descriptions. But the utilities involved said they did not report the incidents to the department because the attacks did not affect the kind of major equipment that could lead to widespread, regional power failures.
One of the incidents not found in DOE’s records cut off power to about 12,000 people for roughly two hours in Maysville, N.C., after a shooting damaged a substation in November, according to a DHS report. The FBI’s investigation into the incident is ongoing, according to the intelligence agency.
The utility affected by the incident, Carteret-Craven Electric Cooperative, reported the incident to NERC’s Electricity Information Sharing and Analysis Center, but didn’t report the attack to DOE because it was a “distribution-level” incident, said Melissa Glenn, a spokesperson for the utility. That means the outages caused by the damage would have been limited to local power customers and not lead to the wider blackouts federal regulators are most concerned with.
In another case unreported to the Energy Department, a substation owned by the East River Electric Cooperative serving the Keystone oil pipeline in South Dakota was attacked by gunfire late at night in July 2022, according to DHS. The incident caused more than $1 million in damage and forced the pipeline to reduce operations while repairs were underway.
East River co-op spokesperson Chris Studer said the utility reported the incident to local law enforcement, which brought in the FBI. East River also reported the incident to NERC and its E-ISAC, along with regional grid agencies, but said it did not report it to DOE because the attack did not affect the bulk power system.
Brian Harrell, a former assistant secretary for infrastructure protection at DHS, said in an email that utilities have too many competing agencies to report to, and suggested reporting be streamlined to NERC’s E-ISAC.
“This lack of consistency, by no fault of the utility, suggests that the numbers may not paint a complete picture,” he said.
Grid experts said these data gaps clearly indicate a lack of understanding about which agencies utilities need to report to and when.
Utilities may be using a “loophole” based on definitions of what constitutes “critical infrastructure,” said Jonathon Monken, a grid security expert with the consulting firm Converge Strategies. He was previously senior director of system resilience and strategic coordination for the PJM Interconnection, the nation’s largest power market.
There are “lots of ways” to work around DOE requirements, Monken added, but as he reads the regulation, utilities are required to report any operational disruptions caused by a physical attack.
“[I]t appears the information you collected shows that companies are still missing the boat when it comes to mandatory reporting,” he said. “Not good.”
One former FERC official who was granted anonymity to speak about a sensitive security issue said the commission also received no alerts from law enforcement officials about the planned and actual attacks that took place last year. That omission hinders agencies’ ability to respond to these kinds of events, the person said.
A spokesperson for FERC declined to comment on the commission’s communications with law enforcement.
But Cancel defended government agencies’ response to these incidents, and said federal investigators may have had specific intelligence reasons for keeping FERC and state utility agencies out of the loop.
“I’m not a lawyer or a law enforcement professional, but you had an active criminal investigation going on,” he said. “I don’t think they wanted to sort of blow the horn on that and compromise the integrity of the investigation.”
An FBI spokesperson offered no direct response to these criticisms in an email, but said the agency “views cybersecurity as a team sport.” The person commented on the condition that the remark be attributed to the bureau.
The FBI urged utility executives last month to attend security training hosted by intelligence agents in order to ensure they are up to speed on the threats posed by bad actors.
“We can’t do it without you,” Matthew Fodor, deputy assistant director of the FBI’s counterterrorism division, said during an all-day FERC technical conference on Aug. 10. “The challenges that we have — and DOE can probably speak to this better than anybody — is limited resources.”
People attacking the electricity supply have thousands of potential targets, including power substations and smaller but critical pieces of utility infrastructure. The smaller pieces often go unprotected because federal standards do not require utilities to secure them.
Nearly half of the 4,493 attacks from 2020 to 2022 targeted substations, according to the NERC briefing from February, making them the most frequent targets for perpetrators over that period.
Details on how to carry out these kinds of attacks are available from extremist messaging boards and other online content, researchers and federal security officials say. These include maps of critical entry points to the grid, along with advice that extremists have gleaned from incidents like the assault in North Carolina.
Stanek, the Maryland electricity regulator, said he was “disappointed with the level of coordination and communication” that federal and state law enforcement displayed in handling the alleged plot in Baltimore. No trial date has been announced for the case, which is in U.S. District Court in Maryland.
Maryland’s Public Service Commission is in charge of ensuring that the state’s power system keeps the lights on. Regulators need to be kept informed of threats to the system so they can coordinate with other agencies in case an attack succeeds, Stanek said.
At the same time, he quipped, maybe he was better off in the dark after all.
“There’s a lot of colorful details in [the FBI report],” Stanek said. He paused, thinking. “And honestly, as a regulator, had I received these details in advance and shared the information with trusted sources within state government, I would have had sleepless nights.”
“So perhaps the feds did a favor by only sharing this information after everything was all said and done,” he added.
#us politics#news#politico#2023#alt right#domestic terrorists#neo nazis#fbi#power grids#power outages#Department of Energy#canada#white nationalists#Federal Energy Regulatory Commission#US electric grid#North American Electric Reliability Corp.#Department of Homeland Security#Office of the Private Sector#counterterrorism#cybersecurity#utility infrastructure#maryland
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Why Accurate Financial Statements Matter for Your Business
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Having a normal one about the events of the Conscience of the King.
Written to go alongside the fic "Regulatory Relations"
Lyrics below the cut!
Nightmares - everybody's got one, and this one is mine
I put the devil in my crosshairs and the bullet went wide
I took my shot but he got away
I know he'll hunt me down someday
I missed my shot at the devil and there's nowhere to hide
He knows my name and he haunts my steps
He'll wear me down till there's nothing left
My soul and my sins and the devil make three
And he's coming, he's coming for me
He's in my dreams and he knows my heart
I feel him reaching from the dark
I got away, but I'll never be free
If he's coming, he's coming for me
And he's coming, he's coming for me
Hell is a pretty little place with nothing to eat
And the devil takes you by the hand and promises meat
He'll chew you up and he'll spit you out
He lifts you up till he lets you drown
You can call his bluff but the house can't be beat
He knows my name and he haunts my steps
He'll wear me down till there's nothing left
My soul and my sins and the devil make three
And he's coming, he's coming for me
He's in my dreams and he knows my heart
I feel him reaching from the dark
I got away, but I'll never be free
If he's coming, he's coming for me
And he's coming, he's coming for me
All I know is this
If you aim at the devil, you'd better not miss
All I know is this
If you aim at the devil, you'd better not miss
If you aim at the devil, you'd better not miss
If you aim at the devil, you'd better not miss
#southern gothic#star trek filk#filk#the conscience of the king#regulatory relations#original music#new music#americana music#SoundCloud
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zooms in on myself in my job, two years down the line. isn't it spooky i can have whole technical conversations now and make strategic decisions because i actually understand the work now?
#realizations i make after my team meeting where im like whoa. im a fully blown useful knowledgeable person now#they arent really carrying me anymore! im just doing it and saying stuff and being confident about it!#also yeah it takes like 2 years to understand this job LOL#the entire structure and the way the org works and the complex regulatory dynamics between fed/state/tribe/city#it's not something you grasp from the outside in. but if i were to switch to another job it would be simpler now#but starting as a brand new fresh out of college employee it takes TIME to even figure out where the limits of our oversight is
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Radical thoughts: in Western societies it is constantly re-debated whether terminating a pregnancy should be illegal, while it is never debated if for example abandoning a partner during pregnacy should be illegal, indicates that the governing structures and politics are still infused with deep sexism. This one-sidedness reveals the debate is really about the right to control women's bodies (and people traditionally deemed women), and not about protecting new life.
#feminism#sexism#abortion rights#politics#i want to clarify i am not taking a side on whether the alternative i mention would be good or not#i am pointing out that the concept of regulatory interference in the traditionally male role in the start of new life is almost non-existent#which indicates a patriachal hang-over in the whole framing of this issue
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National Press Day is observed on November 16, every year, in India to celebrate the importance of a free and responsible press in a democratic society. The day is celebrated to commemorate the establishment of the Press Council of India, which acts as a regulatory body for the news media in the country. #NationalPressDay build your brand with digital media and benefit from social media branding contact Media Heights. By Mediaheightspr.com #Inboundmarketing #MEDIAHEIGHTS #digitalmarketingcompany #searchengineoptimization #content #instagrammarketing #worldcancerday #advertisingagency #web #MEDIAHEIGHTSPRCOM #best #public #relation #agency #in #chandigarh #mohali #punjab #north #india #buildingrelationships #globally #customer #internetbanding — at media heights #smo #branding #facebook #twitter #marketingonline #brand #searchengineoptimization #internetmarketing #follow #digitalagency #marketingagency #motivation #digitalmarketingtips #onlinebusiness #websitedesign #marketingonline #brand #searchengineoptimization #content #instagrammarketing #advertisingagency #web #technology #onlinebranding #branding360degree #SEO #SEObrandingagency #websiteranking #websitetrafic #Digitalmarketing #mediaheights #OnlineAdvertising #instagrammarketing #advertisingagency #web #marketingonline #brand
#National Press Day is observed on November 16#every year#in India to celebrate the importance of a free and responsible press in a democratic society. The day is celebrated to commemorate the esta#which acts as a regulatory body for the news media in the country.#NationalPressDay build your brand with digital media and benefit from social media branding contact Media Heights. By Mediaheightspr.com#Inboundmarketing#MEDIAHEIGHTS#digitalmarketingcompany#searchengineoptimization#content#instagrammarketing#worldcancerday#advertisingagency#web#MEDIAHEIGHTSPRCOM#best#public#relation#agency#in#chandigarh#mohali#punjab#north#india#buildingrelationships#globally#customer#internetbanding — at media heights#smo
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cw ai, suicidal ideation, negativity of all things to not regulate. why AI
#just saw some jpn AI regulatory news being shared in some of the ethical AI servers im in and like#“nah copyright just doesnt apply actually. lol have fun” okay ill kms then!#jpn already has an issue with creatives and workers overworking. this will only make the issue worse!#theres nothing people can do about having their entire identities stolen? ok#negative#ai bs#cw suicidal ideation#like what will there be left to live for lol#cant even create as a hobby because corps will feed anything I share digitally into a machine without my permission!#secret zine club where we physically meet and read each others works (you cant take home a copy)#its viscerally like. evil to me. to just steal someones voice and edit it freely. lol which is what this is about in this case#thats. one of the closest things to being part of their soul. what are you ursula?#why are we in the Bad timeline dude. i hope like hell this somehow comes out in the wash#like this is all some big overreaction on our parts and itll become normal and it isnt as bad as we think#but... idk
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I was writing this in the tags but I want to include sources. I’m gonna tell you why drugs don’t go generic right away, and I want you to know that I don’t agree with the reasoning here, but this is how the system works.
New drugs are priced so much to recoup some of the losses of research. Drug research is insanely expensive. Whether you’re talking about buffers and reagents in the lab, machines designed to give scientists highly specific information, or required animal research, it’s EXPENSIVE. I tried to pull up an example for a standard microscope but companies that make lab equipment don’t have prices on their website, you have to fill out a form to request a quote.
So, lab equipment is expensive. You also have to go through rounds of animal testing. One lab mouse can cost hundreds of dollars, depending on how it has been genetically designed to give the best research results. And spoiler alert, you need repeat results, meaning multiple mice, and then larger lab animals because humans aren’t mice and we need to be sure drugs are safe before testing them on humans. Raising and caring for lab animals also takes lots of highly trained staff, which adds to the expense. This is partially why a lot of scientists in animal research are pushing for alternative research methods, because it is more humane and more cost effective to reduce our reliance on animal models.
So it’s expensive to do research, and then you get into patent law. Drugs get 20 years of patents, although that’s from when the patent was filed - which is often BEFORE the drug hits the market. You can patent a drug and then still have several more years of development. So in practice, drugs are often on the market for less than their patent time. From the drug company’s perspective, they need to recoup their losses in that amount of time, and the high price of the name brand drug is funding the ongoing research of the next drug.
Generic drugs don’t have to go through animal or clinical trials, so companies making generic drugs ONLY have to consider the manufacturing cost when pricing their drugs. This is why they’re so much cheaper, because all they have to prove is that their drug is the same as the patented one.
Lenacapavir is STILL IN CLINICAL TRIALS, according to the source linked above. It hasn’t been approved for prevention. I believe it will probably be approved, but the point is that it’s a very new drug and still within its patent range. I’m not entirely sure when the patent was filed, but the fact is that it will have a generic eventually. Just not right now. But the reasoning for drugs being so expensive is that they’re factoring in the cost of research, not just the cost of production. I don’t like it! It’s a bad system! But that’s why it is the way it is
Source
#I am having trouble finding sources but there’s more complications as well#bc the companies can use their research that they did in the US to support approval in other countries#there are places that just do a lit review and approve drugs if the FDA approved them#but then mandate lower costs#which means that US consumers end up paying more to support the lower prices of other countries#bc we have less regulatory protection#and you have to factor in the way insurance inflates costs bc you have to go through them#I doooont remember which book I read this in though so please question my summary in these tags#like continue being angry at pharma companies because there’s no reason for things like insulin to be expensive#but every once in a while I see things like this where people are like new miracle drug but no generic!!! evil!!!#and I’m like THATS HOW PATENT LAW WORKS#YOU DONT GET TO HAVE A GENERIC WHILE THERE IS AN ACTIVE PATENT#like the real solution would be to abolish capitalism but until we get there#you have to pay the salaries of people who breed mice and manufacture microscopes and maintain microscopes for the scientists to use them#and all of that builds up to expensive drug prices#now if the company would reinvest ALL of that profit into new research I’d be much more okay with higher prices#it’s a taxing the rich problem more than it is a generic vs patent problem
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Why Biomarkers Matter In Bioanalysis- FDA New York - New York City, Buffalo
Biomarkers are transforming the medicine industry by providing insights into disease progression, drug efficiency, and patient health. It is crucial in developing new therapies, clinical trials, and ensuring the safety of medications and the advanced bioanalysis support it. The scientific teams of FDA New York - New York City, Buffalo play a key role in regulating and guiding these innovations. They ensure the safety and effectiveness of new treatments.
What Are Biomarkers?
Biomarkers are measurable indicators of biological states or conditions in the body. These indicators can be genes, proteins, enzymes, or hormones. They are used to identify diseases, measure their progression, or determine how well a treatment is working.
FDA’s Role in Biomarker Research and Bioanalysis:
The regulatory agency FDA New York - New York City, Buffalomanages the approval and regulation of new drugs and therapies that rely on biomarkers. The FDA has set strict guidelines for bioanalysis to ensure that biomarkers used in clinical studies are validated and reliable. By setting guidelines and providing oversight, the FDA New York helps ensure that new therapies are safe and efficient.
How Biomarkers Improve Drug Development and Clinical Trials:
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By Annie Norman
The public learned last fall of one particularly controversial element of United States Postmaster General Louis DeJoy’s 10-year plan for the U.S. Postal Service that would be rolling out soon. Essentially, the function of sorting and delivering mail would be consolidated into regional centers, leaving empty former sorting space in the back of post offices. No layoffs were announced.
At first glance, this sounds innocuous, but seasoned postal observers suspect that with less activity happening at smaller or rural post offices, they become vulnerable to a reduction in hours or closure. This leads to the kind of job losses that initially present as don’t worry, we’ll relocate you to the regional center but are experienced by postal workers as if I don’t commute two hours there and back each day or more, I lose my job.
In response, The Save the Post Office Coalition, which I coordinate, wrote to the Secretary of the USPS Board of Governors to ensure the board was made aware of emails from 160,000 postal customers across the country urging them to stop the disastrous elements of DeJoy’s plan before it’s too late.
Among the several thousands of personalized messages, we highlighted a handful in our note:
“The USPS provides a service to the public. It was never intended to be a profit-making business. I’m disappointed & ashamed at where politics seem to be taking us.”
— David B. (veteran) Seattle, Washington.
“As a former United States Postal Service employee and as someone who regularly uses the [USPS], I ask you to do something about DeJoy, who continues to degrade everything about the postal service — especially the service part of it.”
— Kristin F. in Cottonwood, Indiana.
“It is important for seniors like me to be able to count on a dependable means of getting medications without having a further drain on our resources.”
— Peter L. in Los Angeles, California.
“I believe that a well supported and functioning post office is a hallmark of a healthy, advanced nation. Stop DeJoy’s undemocratic plan now before it’s too late.”
— Janet M. in Downers Grove, Illinois.
“We senior citizens depend on USPS. Please help keep it viable.”
—Joanne L. in Akron, Ohio.
“Our postal service should be about serving us rather than serving businesses that give it money.”
— Douglas L. in Rio Rancho, New Mexico.
We have yet to hear a response or acknowledgement that the messages from the public were received, and DeJoy continues to make it clear that he doesn’t want anyone asking questions about his 10-year plan.
On the same day that USPS leadership received our coalition’s messages, the Postal Regulatory Commission issued a public inquiry order to DeJoy asking that USPS provide details on the sorting and delivery changes under his plan. In the order, the Commission said it “notes that stakeholders have expressed concerns regarding a lack of a forum to explore the impacts of these proposed changes.”
DeJoy responded with an objection to the Commission’s inquiry. On May 17, DeJoy delivered congressional testimony for the first time in nearly two years at a hearing of the House Oversight Subcommittee on Government Operations. Rep. Summer Lee asked him why USPS is objecting. In his response, DeJoy was openly hostile toward the postal regulator, accusing them of actively participating “in the destruction of [USPS].”
Just last month, DeJoy sat down with the press for a 90-minute interview where he once again doubled down with an adversarial attitude toward postal regulators who seek details for the public on his 10-year plan, calling the Commission’s inquiry “nonsense,” saying, “We don’t need to be babysat.”
On May 22, DeJoy delivered the keynote address at the 2023 National Postal Forum where he spoke at length touting his efforts to implement “dramatic changes” and increase the pace of his 10-year plan. The postmaster general told the audience that “dramatic changes must be done at a pace, and with a tenacity that is rarely seen.” However, these changes are a mystery to many, and for a public institution, this mystery is dangerous.
If the past is any guide, the effects of potential post office closings and reduced hours will be devastating, particularly to rural and Indigenous communities. The Save the Post Office Coalition organized a petition to the Postal Regulatory Commission and the USPS Office of Inspector General urging them to stop DeJoy’s “dramatic changes” and demand public input, and so far has received over 131,000 signatures from the public who regularly use the postal service.
The bottom line is that the public has a right to more transparency and input in the decision-making process at a public institution. This requires engagement with said public — which DeJoy is actively resisting. When you put a rich, white, private-sector executive who isn’t used to public accountability and cooperation in charge of a treasured public institution, such a clash might be inevitable. It’s plain DeJoy doesn’t have the temperament for public service.
Communities across the nation want dramatic change at the post office too, but that dramatic change is not to be secretive or a surprise; it must be a shift toward protecting and expanding the public footprint and services available at the post office to meet new needs and change with the times. The People’s Postal Agenda outlines a framework for an expanded USPS that includes things like postal banking, expanded nonbank financial services like bill payment and ATMs, WiFi in parking lots, and public electric vehicle charging.
We still remember former President Donald Trump’s plan to privatize the post office, right before he put his thumb on the scale to have his donor DeJoy appointed as postmaster general. We also remember DeJoy’s role in sowing public fear and uncertainty in the vote-by-mail process by slowing down the mail and then sending out mailers to voters that meeting their state’s deadline would not ensure their vote would arrive in time to be counted, causing him to be sued by the NAACP and Public Citizen, as well as secretaries of state.
There is nothing to suggest that DeJoy has abandoned the privatization vision of the people who got him the job. So it’s our job as citizens to make absolutely sure any upcoming “dramatic changes” to the post office don’t shrink and privatize the institution but protect and expand it for generations to come.
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