#Medicines

[reasonsforhope]

"An international research team has found almost a million potential sources of antibiotics in the natural world.

Research published in the journal Cell by a team including Queensland University of Technology (QUT) computational biologist Associate Professor Luis Pedro Coelho has used machine learning to identify 863,498 promising antimicrobial peptides -- small molecules that can kill or inhibit the growth of infectious microbes.

The findings of the study come with a renewed global focus on combatting antimicrobial resistance (AMR) as humanity contends with the growing number of superbugs resistant to current drugs.

"There is an urgent need for new methods for antibiotic discovery," Professor Coelho, a researcher at the QUT Centre for Microbiome Research, said. The centre studies the structure and function of microbial communities from around the globe.

"It is one of the top public health threats, killing 1.27 million people each year." ...

"Using artificial intelligence to understand and harness the power of the global microbiome will hopefully drive innovative research for better public health outcomes," he said.

The team verified the machine predictions by testing 100 laboratory-made peptides against clinically significant pathogens. They found 79 disrupted bacterial membranes and 63 specifically targeted antibiotic-resistant bacteria such as Staphylococcus aureus and Escherichia coli.

"Moreover, some peptides helped to eliminate infections in mice; two in particular reduced bacteria by up to four orders of magnitude," Professor Coelho said.

In a preclinical model, tested on infected mice, treatment with these peptides produced results similar to the effects of polymyxin B -- a commercially available antibiotic which is used to treat meningitis, pneumonia, sepsis and urinary tract infections.

More than 60,000 metagenomes (a collection of genomes within a specific environment), which together contained the genetic makeup of over one million organisms, were analysed to get these results. They came from sources across the globe including marine and soil environments, and human and animal guts.

The resulting AMPSphere -- a comprehensive database comprising these novel peptides -- has been published as a publicly available, open-access resource for new antibiotic discovery.

[Note: !!! Love it. Open access research databases my beloved.]"

-via Science Daily, June 5, 2024

[nanayll]

[spooniestrong]

10 Medications You Should Never Stop Abruptly - GoodRx

https://www.goodrx.com/drugs/side-effects/dangerous-medications-to-stop-abruptly

[angelnumber27]

Psychiatrists should directly at least even just briefly explain side effects instead of just asking symptoms and being like okay so you’re depressed? Let’s try *enter antidepressant* and boom you’re done. I know prescriptions almost always come with informational papers but I really truly doubt that most people read them. I honestly just feel it’s wrong and very careless to not disclose side effects to a patient and discuss those things with the patient before prescribing a medication.

[athena5898]

(Quds) The Euro-Med Human Rights Monitor has reported that over 70,000 Palestinians are trapped in the northern Gaza Strip, facing starvation and annihilation in the longest genocide campaign in modern history.

The Monitor further highlighted the catastrophic conditions faced by the residents of the North, with no access to food, water, medicines, or medical services, amid relentless Israeli attacks and massacres.

Catastrophic situation in Northern Gaza. Euro-Med Monitor Report +70,000 Palestinians are besieged in northern Gaza, facing starvation and annihilation in the longest genocide campaign in modern history. people in northern Gaza have been besieged for two months without access to food or medicine and amid relentless Israeli attacks Shocking statistics +150,000 Palestinians have been forcibly displaced since the start of Isreal's invasion on October 5

The besieged people are facing a real famine, as all types of food and clean water have run out, while Israeli bombings and military invasions of shelters and homes continue. Hundreds of civilians remain trapped under the rubble caused by Israeli airstrikes unable to be rescued as Israel has blocked civil defense teams from operating for over 41 days. "The international community's disregard for what is happening in northern Gaza represents an indelible stain on its conscience as it continues to exclude Palestinians from the protection of international law and its enforcement mechanisms due to political biases and international pressure." Euro-med Monitor

[whitelotusherald]

Just learned during work that Faramir and Boromir had a third brother who probably died of diabetes; let me introduce you...

[achromaticsideofme]

[mockva]

Chinese medicine

[hallison-bre]

Rob Taxpayer performes Medicines at the Jurassic Park House in Portland, Oregon. 10/20/2011

Video credits to Virginia Holder on YouTube

[soniez]

The Evolution of Thyroid medicines From Early Treatments to Modern Solutions

The thyroid gland plays a vital role in regulating the body’s metabolism, growth, and development.  When the thyroid malfunctions—whether through overactivity (hyperthyroidism) or underactivity (hypothyroidism)—the entire body can feel its effects.  Over the years, thyroid conditions have become more widely recognized, leading to the evolution of effective medications that help manage these disorders.  The development of thyroid medicines has come a long way, transitioning from early rudimentary treatments to modern pharmaceutical innovations that offer patients a higher quality of life.

In this blog, we will explore the history and evolution of thyroid drugs, highlighting how thyroid medicines manufacturers in India and thyroid medicines exporters play a critical role in this process.  Additionally, we will discuss the increasing global demand for thyroid drugs, especially in regions like the Philippines, where thyroid medicines suppliers are crucial in ensuring access to life-saving medications.

The Early Days of Thyroid Treatments

Before modern thyroid drugs were developed, ancient civilizations used various natural remedies to manage symptoms of thyroid disorders.  Historical texts from Egypt, Greece, and China mention goiter, a visible swelling of the thyroid gland, which was often linked to iodine deficiency.  In these ancient times, treatments were rudimentary and primarily focused on addressing visible symptoms like goiter.

In the 19th century, scientific advancements began to shape the course of medical treatments.  One of the first breakthroughs in thyroid treatment came in 1891 when George Murray successfully treated hypothyroidism with thyroid extract derived from sheep.  This was the first instance of hormone replacement therapy and marked the beginning of the pharmaceutical management of thyroid disorders.

The Discovery of Iodine and Its Role in Thyroid Health

In the early 20th century, scientists discovered the importance of iodine in thyroid health.  Iodine is a key component in the production of thyroid hormones—T3 (triiodothyronine) and T4 (thyroxine).  It was found that iodine deficiency was one of the main causes of goiter and hypothyroidism.  This discovery led to the development of iodized salt as a preventive measure against iodine deficiency, significantly reducing the incidence of goiter worldwide.

However, while iodized salt helped prevent thyroid disorders caused by iodine deficiency, it did not address all thyroid conditions.  This led to the continued development of thyroid hormone replacement medicines for those with other forms of thyroid dysfunction.

The Emergence of Synthetic Thyroid medicines

In the mid-20th century, researchers made significant strides in developing synthetic thyroid hormones.  The introduction of synthetic levothyroxine (T4) in the 1950s revolutionized the treatment of hypothyroidism.  Levothyroxine, which is identical to the naturally occurring hormone produced by the thyroid gland, replaced the crude thyroid extracts used in earlier treatments.  Its standardized dosage and predictable absorption made it the gold standard for treating hypothyroidism.

Levothyroxine remains one of the most prescribed thyroid drugs globally, helping millions of patients manage their condition effectively.  Today, it is produced by leading thyroid medicines manufacturers in India and other countries, ensuring consistent quality and supply to meet global demand.

In addition to levothyroxine, synthetic T3 drugs, such as liothyronine, were developed to treat hypothyroidism.  While T3 medicines are less commonly prescribed than T4 medicines, they offer an alternative for patients who do not respond well to T4 therapy.

The Modern Approach to Thyroid Treatment

With the advancement of medical research and technology, the approach to thyroid treatment has become more sophisticated.  The focus is now on personalized medicine, where treatments are tailored to the individual’s specific thyroid hormone levels, symptoms, and overall health.

Thyroid hormone replacement therapy remains the cornerstone of treatment for hypothyroidism, but doctors now have a better understanding of the nuances in dosing and management.  For example, some patients benefit from a combination of T4 and T3 therapies, while others may require adjustments based on factors like age, weight, and the presence of other medical conditions.

The rise of thyroid medicines manufacturers in India has been instrumental in meeting the growing demand for thyroid medications.  Indian manufacturers are known for producing high-quality, cost-effective thyroid drugs, making these treatments accessible to patients worldwide.  In particular, Indian pharmaceutical companies have made significant contributions as thyroid medicines exporters, ensuring that countries with limited pharmaceutical production capabilities have access to life-saving medications.

Global Demand for Thyroid Drugs

Thyroid disorders are common worldwide, affecting millions of people.  Hypothyroidism, in particular, is a widespread condition that requires ongoing treatment with thyroid hormone replacement drugs.  As awareness of thyroid health increases, so does the demand for effective medications.

India has emerged as a key player in the global pharmaceutical market, with many thyroid drugs manufacturers in India producing a wide range of thyroid medications.  These manufacturers are able to meet both domestic and international demand by adhering to strict quality control measures and complying with global regulatory standards.

Indian companies are also recognized as leading thyroid drugs exporters, supplying medications to countries across Asia, Africa, Europe, and North America.  For example, in the Philippines, thyroid disorders are a significant public health issue.  Thyroid medicines suppliers in the Philippines rely on Indian manufacturers to provide a consistent supply of high-quality thyroid medications to meet the needs of their population.

The Role of Thyroid Drugs Suppliers in the Philippines

In countries like the Philippines, access to reliable thyroid medications is crucial for managing the high prevalence of thyroid disorders.  The Philippines faces unique challenges in terms of healthcare access, particularly in rural areas where medical resources may be limited.  As a result, thyroid medicines suppliers in the Philippines play an essential role in ensuring that patients have access to the medications they need.

By partnering with Indian thyroid drugs exporters, suppliers in the Philippines can provide patients with affordable and effective thyroid treatments.  This collaboration helps address the healthcare needs of a growing population and ensures that patients receive timely and consistent care.

The Future of Thyroid Drugs

As research into thyroid disorders continues to evolve, so too does the development of new and improved thyroid drugs.  Scientists are exploring new ways to optimize hormone replacement therapy, including the development of long-acting thyroid drugs that could reduce the need for daily dosing.  Additionally, advancements in biotechnology may lead to the creation of more personalized treatments based on genetic and molecular profiling.

Another area of focus is improving the delivery of thyroid drugs.  While oral tablets are the standard form of treatment today, researchers are investigating alternative delivery methods, such as transdermal patches and injectable formulations, which may offer more convenient options for patients.

As the pharmaceutical industry continues to innovate, thyroid medicines manufacturers in India are expected to remain at the forefront of these developments, producing the next generation of thyroid treatments.  With a strong presence as both manufacturers and exporters, Indian companies will continue to play a critical role in meeting the global demand for thyroid drugs.

Conclusion

The evolution of thyroid medicines from early treatments to modern solutions is a testament to the advancements in medical science and pharmaceutical manufacturing.  Today, patients with thyroid disorders have access to safe, effective, and affordable treatments that allow them to lead healthy, normal lives.

India’s pharmaceutical industry, particularly thyroid medicines manufacturers and thyroid medicines exporters, has played a key role in ensuring that thyroid medications are available to patients worldwide.  In regions like the Philippines, thyroid medicines suppliers are essential in meeting the needs of those affected by thyroid disorders, helping them access the treatments they require.

As we look to the future, continued innovation and collaboration within the pharmaceutical industry will further enhance the quality and accessibility of thyroid medicines, ensuring that patients everywhere receive the best possible care.

[sirswooshnoodles]

Me when the medicine that listed bad aftertaste in its possible side effects has a bad aftertaste:

[earlgreydarkchocolate]

The world is a curse, it'll kill if you let it

I know they got pills that can help you forget it

They bottle it, call it medicine

But I don't need drugs

- High enough, K Flay

[legolonia]

Norm Alguy.

I tell you Norm, everyone our age needs a walk in medicine cabinet.

#lego #mini figure #toys #toy-photography #legophotography #greyscale #blackandwhite #fun #livingwithfibromyalgia #chronicfatigue #normalguy #legolonia #awesome #minifig #playwell #staywell #justanormalguylivinganormallife #olympus #desktopphotography #lifeisgood #medicines #medicinecabinet #walkin #oldmates

[blackpointgame]

pharmacy 🆘 #pharmacy #farmacia #sos #Botica #薬 #boticariagarcia #simbolo局 #medicines #ia #logo_pharmacy #vector #icon #logo #marbles #canicas #art #metaverso #aabon35 #artificial_intelligence #canica http://aabon35.blogspot.com http://arubio28814.blogspot.com

[mockva]

Medicines from Midjourney