#Lisa Sanders

[pandemic-info]

What Is Long COVID? Understanding the Pandemic’s Mysterious Fallout > News > Yale Medicine

Originally published: April 15, 2024. Updated: June 4, 2024

Just weeks after the first cases of COVID-19 hit U.S. shores, an op-ed appeared in The New York Times titled “We Need to Talk About What Coronavirus Recoveries Look Like: They're a lot more complicated than most people realize.”

...

Unlike most diseases, Long COVID was first described not by doctors, but by the patients themselves. Even the term “Long COVID” was coined by a patient. Dr. Elisa Perego, an honorary research fellow at University College in London, came up with the hashtag #LongCOVID when tweeting about her own experience with the post-COVID syndrome. The term went viral and suddenly social media, and then the media itself, was full of these stories.

Complaints like "I can't seem to concentrate anymore" or "I'm constantly fatigued throughout the day" became increasingly common, seemingly appearing out of nowhere. With nothing abnormal turning up from their many thorough lab tests, patients and their physicians were left feeling helpless and frustrated.

The World Health Organization (WHO) has defined Long COVID as the "continuation or development of new symptoms three months after the initial SARS-CoV-2 infection, with these symptoms lasting for at least two months with no other explanation." This deliberately broad definition reflects the complex nature of this syndrome. We now understand that these symptoms are wide-ranging, including heart palpitations, cough, nausea, fatigue, cognitive impairment (commonly referred to as "brain fog"), and more. Also, many who experience Long COVID following an acute infection face an elevated risk of such medical complications as blood clots and (type 2) diabetes.

In April 2024, an estimated 5.3% of all adults in the United States reported having Long COVID, according to the Centers for Disease Control and Prevention (CDC). Data from the CDC suggest that Long COVID disproportionately affects women, and individuals between the ages of 40 and 59 have the highest reported rates of developing this post-acute infection syndrome.

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Inderjit Singh, MBChB, a YSM assistant professor specializing in pulmonary, critical care, and sleep medicine, and director of the Pulmonary Vascular Program, is actively engaged in clinical trials aimed at uncovering the fundamental underpinnings of Long COVID.

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Through this work, a significant revelation emerged. They observed that patients grappling with Long COVID and facing exercise difficulties were unable to efficiently extract oxygen from their bloodstream during physical exertion. This discovery identifies a specific cause underlying the biological underpinnings of Long COVID.

... Dr. Singh, along with other researchers, is focused on the identification of blood-based markers to assess the severity of Long COVID. For example, a research group, led by Akiko Iwasaki, PhD, Sterling Professor of Immunobiology and Molecular, Cellular, and Developmental Biology, and director of the Center for Infection & Immunity at YSM, most recently created a new method to classify Long COVID severity with circulating immune markers.

Further investigations conducted by Dr. Singh's team identified distinctive protein signatures in the blood of Long COVID patients, which correlated with the degree of Long COVID severity. Researchers identified two major and distinct blood profiles among the patients. Some of them exhibited blood profiles indicating that excessive inflammation played a prominent role in their condition, while others displayed profiles indicative of impaired metabolism.

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Researchers currently believe that the impairment of a spectrum of key bodily functions may contribute to these diverse symptoms. These potential mechanisms include compromised immune system function, damage to blood vessels, and direct harm to the brain and nervous system. Importantly, it's likely that most patients experience symptoms arising from multiple underlying causes, which complicates both the diagnosis and treatment of Long COVID.

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The last word from Lisa Sanders, MD:

I’m the internist who sees patients at Yale New Haven Health’s Multidisciplinary Long COVID Care Center. In our clinic, patients are examined by a variety of specialists to determine the best next steps for these complex patients. Sometimes that entails more testing. Often patients have had extensive testing even before they arrive, and far too often—when all the tests are normal—both doctors and patients worry that their symptoms are “all in their head.”

One of our first tasks is to reassure patients that many parts of Long COVID don’t show up on tests. We don’t know enough about the cause of many of these symptoms to create a test for them. The problem is not with the patient with the symptoms, but of the science surrounding them. If any good can be said to come out of this pandemic, it will be a better understanding of Long COVID and many of the other post-acute infection syndromes that have existed as long as the infections themselves.

[apollo-gate]

Lisa

[minionwater]

YOUCANT DO THAT.,

[rinabirgul]

[dbdshitthatnobodyaskedfor]

your MBTI your character pt 2

[dreaminginthedeepsouth]

Moon setting over Carrabelle Harbor, Florida, captured by Lisa Lacasse :: [Our Little Secret on St. George Island]

* * * *

From C.S. Lewis', 'Till We Have Faces':

"Now we see but a poor reflection as in a mirror; then we shall see face to face. Now I know in part; then I shall know fully, even as I am fully known."

"When the time comes to you at which you will be forced at last to utter the speech which has lain at the center of your soul for years, which you have, all that time, idiot-like, been saying over and over, you'll not talk about the joy of words. I saw well why the gods do not speak to us openly, nor let us answer. Till that word can be dug out of us, why should they hear the babble that we think we mean? How can they meet us face to face till we have faces?"

"The sweetest thing in all my life has been the longing - to reach the Mountain, to find the place where all the beauty came from - my country, the place where I ought to have been born. Do you think it all meant nothing, all the longing? The longing for home? For indeed it now feels not like going, but like going back."

[h/t Ian Sanders]

[brandonxdylan]

[lizabethstucker]

The Year's Best Science Fiction, 12th Annual Collection

3.5 out of 5

A collection of twenty-three of 1994's best science fiction stories as selected by editor Gardner Dozois.

The book begins with Dozois' extensive summary of the year in science fiction and his concerns for the future of science fiction as a genre. Reading his 1994 observations in 2024, thirty years later, is both jarring and sad when you consider how many of the magazines mentioned no longer exist. I know most genre fiction (mystery, science fiction, fantasy in particular) go through moments where writers, critics, and anthologists are worried/predicting its destruction. I can remember hearing that worry in the late 1960s (science fiction), the 1970s (fantasy), and pretty much every decade for mystery. It never really happened, although there were always growing pains as the tropes changed. I've stopped worrying about it.

There's a fair mix of humor and angst, tragedy and farce within these pages, which I personally appreciate as it keeps the reading experience from becoming monotonous.

Contents

"Forgiveness Day" by Ursula K. Le Guin, 4 out of 5. "The Remoras" by Robert Reed, 4.5 out of 5. "Nekropolis" by Maureen F. McHugh, 3 out of 5. "Margin of Error" by Nancy Kress, 4.5 out of 5. "Cilia-of-Gold" by Stephen Baxter, 2.5 out of 5. "Going After Old Man Alabama" by William Sanders, 3.5 out of 5. "Melodies of the Heart" by Michael F. Flynn, 5 out of 5. "The Hole in the Hole" by Terry Bisson, 3.5 out of 5. "Paris in June" by Pat Cadigan, 2 out of 5. "Flowering Mandrake" by George Turner, 3 out of 5. "None So Blind" by Joe Haldeman, 3 out of 5. "Cocoon" by Greg Egan, 4 out of 5. "Seven Views of Olduvai Gorge" by Mike Resnick, 4.5 out of 5. "Dead Space for the Unexpected" by Geoff Ryman, 3 out of 5. "Cri de Coeur" by Michael Bishop, 3 out of 5. "The Sawing Boys" by Howard Waldrop, 2 out of 5. "The Matter of Seggri" by Ursula K. Le Guin, 4 out of 5. "Ylem" by Eliot Fintushel, 3 out of 5. "Asylum" by Katharine Kerr, 4.5 out of 5. "Red Elvis" by Walter Jon Williams, 3 out of 5. "California Dreamer" by Mary Rosenblum, 3 out of 5. "Split Light" by Lisa Goldenstein, 3 out of 5. "Les Fleurs du Mal" by Brian Stableford, 3 out of 5.

Some of my favorites include: "Margin of Error" which had a particularly satisfying revenge; "Melodies of the Heart" almost killed me emotionally; and "Asylum" which is frighteningly close to what we are facing in 2024.

A few of the stories disappointed me greatly, having such wonderful plots, terrific flow, and interesting characters, only to crash and burn the endings. No matter how great a story might be, if you can't stick the ending, it's all for nothing. Despite that, I'm still glad that I picked up this collection at the Friends of the Library store.

[hannaedits]

Five-Star Reads for July 2024

[moviesandmania]

WEREWOLF CABAL (2022) Reviews and now free to watch online

‘Welcome to the pack…’ Werewolf Cabal is a 2022 British comedic horror film about an American author who uncovers a secret cult of people who worship a lycanthrope. Written, directed and co-produced by Chris Sanders (Demons at Dawn; Blood Prison short; Nest of Vampires). Also produced by Steven Robert Alexander. The Black Coppice Films-Jacuzzi Entertainment production stars Vernon Wells, Dani…

[pandemic-info]

What Is Long COVID? Understanding the Pandemic’s Mysterious Fallout > News > Yale Medicine

[microcosmtoxin]

election good news

in delaware, sarah mcbride became the first openly trans person to be elected to the us congress

in north carolina, democrat josh stein will defeat self proclaimed "black nazi" and "pervert" mark robinson for the governorship

new york, maryland, and colorado all added reproductive right protections to their state constitution through a vote on an amendment

for the first time in history, two black women will serve in the senate, newly elected lisa blunt rochester (de) and angela alsobrooks (md)

kentucky rejected a constitutional amendment which would undermine public education by forcing public school dollars to go to non-public school

former democratic states attorney of florida monique worrell won her job back after ron desantis forced her out

palestine supporter bernie sanders won his fourth term in the senate representing vermont

despite fears, there have been no reports of any political violence or widescale voter intimidation and fraud

you will still wake up tomorrow

[dustymarcus]

DustyMarcus on hard working musicians

[mushi-shield]

We want justice for Lisa Edwards! Lisa was physically disabled and was in the care and custody of Knoxville Police Department when she became unresponsive. KPD refused to get her the medical attention she desperately and clearly needed, after pleading and begging for it repeatedly. It is very clear by the body cams of the officers, Lisa was in respiratory distress and had strong signs of a stroke. She had slurred speech, paralysis on the left side of her body, and release of bodily fluids. She told KPD repeatedly that she had a stroke, couldn’t walk, and couldn’t breathe. After being mocked, laughed at, ridiculed, degraded, berated, taunted, cursed at, tortured, etc., KPD failed their duty to protect and serve. Ultimately, because of negligence from KPD and Fort Sanders Regional Medical Center, Lisa died. We want Justice! We want the four KPD officers (Sgt. Brandon Wardlaw, Officer Adam Barnett, Officer Timothy Distasio, and Transportation Officer Danny Dugan) held accountable for their actions. We want the medical staff, including security, at Fort Sanders Medical Center held accountable for their actions. We also want policies and procedures changed, put into action, and enforced by all parties responsible for these hideous and horrific acts of negligence.

Why is this important?

The family, friends, community, and country of Lisa Edwards deserve justice!

[mushi-shield]

Lise Kept saying she is having a stroke, that poor women knew she was having a stroke and no one believe her. they just laugh at her, and called her a liar. they was hurting her she cry out in pain and they told her to shut up to just shut up. 

and one cop yelled at her and said “it’s the lords day, and all I want to do is get some coffee and oatmeal” and i don’t want to deal with your mess, we already spent to much time with you this morning. 

when she said she going to pass out ( the same cop told her) you not going to pass out you know what  go get in here and pass out so we can be done with you.)  

here the video of the  arrest of Lisa Edwards but it’s heartbreaking. 

Please don't ignore this: but I hope you heard about the recent case of the death of Lisa Edwards. It happened just a few days ago and shows how fucked up America is when it comes to health insurance and the police. You have to watch the video. It is horrific.

I have not heard about this case, but after getting caught up: holy fucking shit.

For anyone who also didn't know, Lisa Edwards was a 60-year-old woman who was discharged from Fort Sanders Regional Medical Center (I feel it's important to name and shame this hospital) on February 5 of this year. Lisa refused to leave because she still felt as if she were in a medical emergency. The hospital staff ended up calling the cops on her for "trespassing."

As the cops tried to arrest her, Lisa repeatedly asked for help and said she felt like she was going to die. All the while the cops kept telling her that they didn't believe her. Eventually, Lisa had a stroke and passed away in the back of a police car.

Not only are the cops at fault here, I think Lisa's family should definitely sue the hospital. She should have never been discharged, and the cops should have never been called. So many people fucked up here; this woman was clearly having a life-threatening medical emergency and she was treated so callously by everyone involved. It won't bring her back, but I really hope her family sues the shit out of everyone involved to make an example. I truly hope they'll eventually find peace, nobody should ever have to go through this.