#Fentanyl

[mysharona1987]

[reasonsforhope]

"For the first time in decades, public health data shows a sudden and hopeful drop in drug overdose deaths across the U.S.

"This is exciting," said Dr. Nora Volkow, head of the National Institute On Drug Abuse [NIDA], the federal laboratory charged with studying addiction. "This looks real. This looks very, very real."

National surveys compiled by the Centers for Disease Control and Prevention already show an unprecedented decline in drug deaths of roughly 10.6 percent. That's a huge reversal from recent years when fatal overdoses regularly increased by double-digit percentages.

Some researchers believe the data will show an even larger decline in drug deaths when federal surveys are updated to reflect improvements being seen at the state level, especially in the eastern U.S.

"In the states that have the most rapid data collection systems, we’re seeing declines of twenty percent, thirty percent," said Dr. Nabarun Dasgupta, an expert on street drugs at the University of North Carolina.

According to Dasgupta's analysis, which has sparked discussion among addiction and drug policy experts, the drop in state-level mortality numbers corresponds with similar steep declines in emergency room visits linked to overdoses.

Dasgupta was one of the first researchers to detect the trend. He believes the national decline in street drug deaths is now at least 15 percent and could mean as many as 20,000 fewer fatalities per year.

"Today, I have so much hope"

After years of wrenching drug deaths that seemed all but unstoppable, some researchers, front-line addiction workers, members of law enforcement, and people using street drugs voiced caution about the apparent trend.

Roughly 100,000 deaths are still occurring per year. Street drug cocktails including fentanyl, methamphetamines, xylazine and other synthetic chemicals are more poisonous than ever.

"I think we have to be careful when we get optimistic and see a slight drop in overdose deaths," said Dan Salter, who heads a federal drug interdiction program in the Atlanta-Carolinas region. "The last thing we want to do is spike the ball."

But most public health experts and some people living with addiction told NPR they believe catastrophic increases in drug deaths, which began in 2019, have ended, at least for now. Many said a widespread, meaningful shift appears underway.

"Some of us have learned to deal with the overdoses a lot better," said Kevin Donaldson, who uses fentanyl and xylazine on the street in Burlington, Vermont.

According to Donaldson, many people using fentanyl now carry naloxone, a medication that reverses most opioid overdoses. He said his friends also use street drugs with others nearby, ready to offer aid and support when overdoses occur.

He believes these changes - a response to the increasingly toxic street drug supply - mean more people like himself are surviving.

"For a while we were hearing about [drug deaths] every other day. When was the last one we heard about? Maybe two weeks ago? That's pretty few and far between," he said.

His experience is reflected in data from the Vermont Department of Health, which shows a 22 percent decline in drug deaths in 2024.

"The trends are definitely positive," said Dr. Keith Humphreys, a nationally respected drug policy researcher at Stanford University. "This is going to be the best year we've had since all of this started."

"A year ago when overdose deaths continued to rise, I was really struggling with hope," said Brad Finegood, who directs the overdose crisis response in Seattle.

Deaths in King County, Washington, linked to all drugs have dropped by 15 percent in the first half of 2024. Fatal overdoses caused by street fentanyl have dropped by 20 percent.

"Today, I have so much hope," Finegood said.

-via NPR, September 18, 2024. Article continues below with an exploration of the whys (mostly unknown) and some absolutely fucking incredible statistics.

Why the sudden and hopeful shift? Most experts say it's a mystery

While many people offered theories about why the drop in deaths is happening at unprecedented speed, most experts agreed that the data doesn't yet provide clear answers.

Some pointed to rapid improvements in the availability and affordability of medical treatments for fentanyl addiction. "Expansion of naloxone and medications for opioid use disorder — these strategies worked," said Dr. Volkow at NIDA.

"We've almost tripled the amount of naloxone out in the community," said Finegood. He noted that one survey in the Seattle area found 85 percent of high-risk drug users now carry the overdose-reversal medication.

Dr. Rahul Gupta, the White House drug czar, said the drop in drug deaths shows a path forward.

"This is the largest decrease on record and the fifth consecutive month of recorded decreases," he said.

Gupta called for more funding for addiction treatment and healthcare services, especially in Black and Native American communities where overdose deaths remain catastrophically high.

"There is no way we're going to beat this epidemic by not focusing on communities that are often marginalized, underserved and communities of color," Gupta said.

"Overdose deaths in Ohio are down 31 percent"

Indeed, in many states in the eastern and central U.S. where improvements are largest, the sudden drop in drug deaths stunned some observers who lived through the darkest days of the fentanyl overdose crisis.

"This year overdose deaths [in Ohio] are down 31 percent," said Dennis Couchon, a harm reduction activist. "The deaths were just plummeting. The data has never moved like this."

"While the mortality data for 2024 is incomplete and subject to change, Ohio is now in the ninth consecutive month of a historic and unexpected drop in overdose deaths," said the organization Harm Reduction Ohio in a statement.

Missouri is seeing a similar trend that appears to be accelerating. After dropping by 10 percent last year, preliminary data shows drug deaths in the state have now fallen roughly 34 percent in the second quarter of 2024.

"It absolutely seems things are going in the right direction, and it's something we should feel pleased about," said Dr. Rachel Winograd, director of addiction science at the University of Missouri St. Louis, who also noted that drug deaths remain too high.

"It feels wonderful and great," said Dr. Mark Levine, head of the Vermont Health Department. "We need encouraging data like this and it will help sustain all of us who are actively involved in trying to have an impact here."

Levine, too, said there's still "plenty of work left to do."" ...

Dasgupta, the researcher at the University of North Carolina, agreed more needs to be done to help people in addiction recover when they're ready.

But he said keeping more people alive is a crucial first step that seemed impossible only a year ago.

"A fifteen or twenty percent [drop in deaths] is a really big number, an enormous impact," he said, calling for more research to determine how to keep the trend going.

"If interventions are what's driving this decline, then let's double down on those interventions."

-article via NPR, September 18, 2024

[longreads]

The Top 5 Longreads of the Week

In this week's Top 5:

* A Bitcoin-fuelled health nightmare in Texas (Time Magazine) * The hidden history of oil in Los Angeles (Noēma) * Buying fentanyl components online (Reuters) * Preservation over profit in Alberta, Canada (The Narhwal / The Globe and Mail) * Wayfinding with hand-drawn maps (The New York Times)

Learn why our editors are recommending these stories.

[liberalsarecool]

Republicans have no actual morality. It's all theatre. Fentanyl is a prop.

[probablyasocialecologist]

Michelle Tandler – a former venture capitalist and wealthy “anti-San Francisco influencer“ – publicly bemoaned the lack of vigilante groups in the Bay area as she mused about whether or not fentanyl sellers should be lynched. As a researcher who studies drug prohibition, I responded by pointing out that not only is this kind of bloodthirsty rhetoric abhorrent, but drug sellers are, for the most part, workers entrapped in a violent system of marginalization, trying to survive where they have been denied functional access (often through systemic racism) to the licit job market. I pointed out, as my colleagues and I often do, that prohibition is in fact a root cause of most of the harm and chaos stemming from the drug trade. Legalization and regulation would save many lives. Even Twitter owner Elon Musk weighed in on this contentious discussion, surprising many with his stance in favour of the legalization of fentanyl. Despite this, I received dozens of threats and harassing messages for stating a position backed up by evidence.

[...]

Prohibition isn’t fighting the fentanyl crisis – it helped create it in the first place. The more the police crack down – while little is done to address the root question of why so many people want painkillers – the more they push it underground. Drug busts incentivize the flooding of the market with more compact, stronger drugs. More potent drugs are easier to transport and hide, but they’re also more dangerous as they’re difficult to properly dose. It happens every time prohibition is implemented, from the banning of alcohol in the U.S. in the 1920s and 30s, which had the unintended consequence of displacing beer and wine with the consumption of harder liquors, all the way up to the present day, where fentanyl has largely replaced heroin – which replaced morphine, which replaced opium (which was made illegal in Canada in 1908).

Despite countless aggressive attempts, no amount of surveillance or state violence has been able to stamp out drugs, which are available even in prisons, the most heavily guarded places on Earth. This is not to say we should give up the fight to keep people safe from overdoses. Quite the opposite. It means we need to let go of old, punitive, ineffective methods and start trying approaches that actually make practical sense. We have to respect the dignity of our fellow human beings who are struggling and in pain.

[insidetheneedle]

I was staying in a hotel & there were 0 forks at the gas station so I had to IMPROVISE.

IMPROVISE. ADAPT. OVERCOME.

[bed-wed-behead-your-fave]

femtanyl from real life

[mindblowingscience]

Scientists at the University of Florida have identified a novel compound aimed at improving the treatment of opioid overdoses, which claimed the lives of more than 81,000 Americans last year. The discovery could combat the devastating epidemic of opioid-related deaths, driven predominantly by the proliferation of fentanyl. The highly potent synthetic opioid is a pain reliever and among the nation's most abused substances. "Fentanyl is driving the need to find better treatments for opioid overdoses," said Jay McLaughlin, Ph.D., a professor of pharmacodynamics in the UF College of Pharmacy. "Every opioid death is preventable, highlighting the immediate need to improve the treatment options."

Continue Reading.

[selfmedblves]

I want to be able to have an unlimited supply of opioids. Please. I just want to forever feel that calming, blissful warmth. I like feeling all my worries go away. I don't care about recovering at this point. My life sucks and I wanna get fucked up.

[mcelquotes]

My first job will always be to cheer you up, so honestly, if I need to bomb on Sawbones to put a smile on your face, I will absolutely do it every time.

Justin McElroy

[mysharona1987]

This gives off Succession vibes:

[brokenxheart]

Heroin, Oxymorphone 40 & Oxycontin 80 🖤

[whiterockbellringer-browndustnod]

Oh, I've fucked up big time now. I knew it was only a matter of time :( at least the slo mo video looks cool.

[wokstarslush]

[mapsontheweb]

In 2022, fentanyl was responsible for over 200 deaths every day in the US.

by u/USAFacts_Official