#Chromosome Disorders Treatment

[thefocusfoundation]

Find The Right Chromosome Disorders Treatment Options For Your Loved Ones

https://thefocusfoundation.org/ - The Focus Foundation is a research-based agency dedicated to identifying & assisting families & children who have Sex Chromosome Disorders, Dyslexia, and Developmental Dyspraxia. They provide the Best Chromosome Disorders Treatment. For more information visit thefocusfoundation.org.

[intersexalastor]

i've really been thinking about intersex touya and exactly what his experience was

[cannabiscomrade]

February 6-10 is Feeding Tube Awareness Week!

The beginning of February was selected because of its proximity to Valentine’s Day, because we love our feeding tubes. This is my first year as a tubie and I’m looking forward to learning more about feeding tubes and the conditions that necessitate them! I do love my tube, it saved my life!

I am an adult with a feeding tube, and a lot of the awareness and attention surrounding these medical devices is child focused. A lot of children depend on tube feeding to thrive, but there are plenty of disabled adults that depend on tube feeding as well! In 2017 there were approximately 438,000 people with feeding tubes in the US, and 60% of them are adults.

I have gastroparesis, which directly translates to paralysis of the stomach. My stomach doesn’t grind food the way it’s supposed to, and my pylorus sphincter at the bottom of my stomach doesn’t open well to pass food and liquids through. While gastroparesis has a range of impact and severity, I have a very severe case, and I am no longer able to eat or drink by mouth for nutrition. I am 100% tube fed. I went into starvation ketoacidosis prior to my placement.

Tube feeding, or enteral nutrition, has several different forms. There are nasal tubes and there are surgical tubes. Nasal tubes can go into your stomach (NG), duodenum (ND), or your jejunum (NJ) and are typically for short-term use. They can be used for acute illness and malnutrition, or to trial tolerance of enteral feeding. Surgical tubes go into your stomach (gastrostomy/G) jejunum (jejunostomy/J) or both (gastrojejunostomy/GJ) and they’re for chronic conditions and/or long-term use. I have a GJ tube and it looks like this:

I have a GJ tube so that I can bypass my paralyzed stomach and feed directly into my intestine. I can also drain stomach contents from the gastric port, which allows me to drink liquids and drain them out before they make me sick. Different people will have different tubes depending on their diagnosis and prognosis! Some people have one form of tube, and others have separate G and J tubes.

There are over 400 conditions that can require tube feeding. Some of those include

Gastroparesis

Intestinal dysmotility

Cancer

Intestinal failure

Inflammatory Bowel Disease (Crohn’s disease and Ulcerative Colitis)

Cerebral Palsy

Congenital/chromosomal conditions

Cyclic Vomiting Syndrome

Ehlers-Danlos Syndrome

Several trisomy conditions

Prematurity

Other conditions not mentioned in the link above include

Hyperemesis gravadarium, severe nausea/vomiting during pregnancy to the point of significant weight loss and electrolyte imbalance

Acute trauma requiring bowel rest

Eating disorders

This week, I want to promote visibility for disabled adults with feeding tubes. I didn’t know anything about enteral nutrition until I got sick. Once I had a confirmed diagnosis of gastroparesis, the reality that I was facing forced me to learn and adapt quickly to a completely life changing treatment. I know there are other adults like me, as well as tubie adults that used to be a child with a tube!

[rootjin]

actual sciene regarding being “trans”

sex dysphoria - you don’t accept your genitalia. like your body genuinely rejects it. comparable to body integrity disorder. yes, it’s a diagnosis, it’s a disorder.

treatment? cognitive behavioral therapy or medications. if that doesn’t work the last (!) option is to change your genitalia and hope that that will actually help.

you don’t have sex dysphoria? than you don’t need gender-affirming surgery. you’re not “trans”. you either fell victim to the patriarchy’s gender roles, “trans movement’s” gender ideology or are simply a autogynophile.

are you a woman/man after surgery? no. a woman needs XX chromosome and a man needs XY chromosome. that is a scientific fact.

[vavuska]

Imane Khelif.

In 2018 AIBA Women's World Boxing Championships, Khelif participated for the first time, where she ranked 17th after being eliminated from the first round.

In the 2019 AIBA Women's World Boxing Championships held in Russia, where she ranked 33rd after being eliminated from the first round against Natalia Shadrina.

Khelif represented Algeria in the lightweight event at the 2020 Summer Olympics in Tokyo. She was defeated by Ireland's Kellie Harrington in the quarterfinals.

Khelif participated in the 2022 IBA Women's World Boxing Championships, she faced Ireland's Amy Broadhurst in the final and was defeated.

She is not a warmachine. Khelif is a biological woman. Khelif is NOT transgender or transsexual. In Algeria, the country that Khelif represents, transgender identity is prohibited, changing sex or gender is not allowed in official documents, nor are medical or hormonal treatments allowed to transition to another sex. If she was transgender, Khelif would not be able to rapresent her country at all nor travel with an official passport with a female identity!

However, pop up this rumor she was disqualified from 2023 IBA's Women's World Boxing Championships due to high levels of testosterone. Later this was debunked by the same organization. Potentially, could be doping and it was all covered up by sport industry.

Edit: This disqualification happened three days after Khelif defeated Azalia Amineva, a previously unbeaten Russian athlete. The disqualification restored the Russian boxer's undefeated record and IBA has huge ties with the Russian government: the president Kremlev is a Putin supporter and the International Olympic Committee (IOC) expressed concerns about the IBA under Kremlev's leadership. The IOC has also been alarmed by the fact that the IBA's only sponsor was a Russian state-owned energy company (Gazprom) that supports the Russian invasion of Ukraine. Imane Khelif is a UNICEF ambassador, which could again have been seen as a problem by Russian-led IBA, since UNICEF condemned Russian invasion of Ukraine. IBA's allegations that Khelif had failed unspecified eligibility tests are suspicious, expecially because no medical evidence that Khelif has XY chromosomes or elevated levels of testosterone has been published.

The International Olympic Committee (IOC), cleared Khelif to compete in the 2024 Summer Olympics in Paris, confirming that she complied with all necessary eligibility and medical regulations for the event. The IOC noted that Khelif was a woman according to her passport and that this was not a "transgender issue".

She defeated Angela Carini in 42 seconds at the 2024 Olympics, after Carini decided to withdraw citing intense pain in her nose.

This remember me the 'Caster Semenya' case: after Semenya's victory at the 2009 World Championships, she was made to undergo sex testing, and cleared to return to competition the following year. The decision to perform sex testing sparked controversy in the sporting world and in Semenya's home country of South Africa. Later reports disclosed that Semenya has the intersex condition 5α-reductase 2 deficiency and natural testosterone levels in the typical male range.

In 2019, new World Athletics rules came into force preventing athletes like Semenya with certain disorders of sex development (DSDs) from participating in 400m, 800m, and 1500m events in the female classification, unless they take medication to suppress their testosterone levels. Semenya has filed a series of legal cases to restore her ability to compete in these events without testosterone suppression, arguing that the World Athletics rules are discriminatory.

As Khelif, Semenya is cis and has been accused by many people to be trans. Her story has, again, been used and abused to support the anti-trans agenda, claiming that two ciswomen are trans and are unfairly competing with women due to their superior "men strength".

I think Angela Carini was anxious and scared by days of reporter and far-right rumors about how Khelif is incredibly strong and unbeatable, even if Carini has better statistics and more victories in her career than Khelif herself (who was already a Olympics athlete), she was strumentalized by far-right propaganda and made a scene during the match due to anti-trans panic.

J. K. Rowling and Elon Musk, as always, had their small moment of shaming athletes. Most of people think that Carini has been strumentalized by anti-trans Italian propaganda and after being called out for harassing a cisgender woman, she claimed to be sorry for not having respected her adversary during the match.

Edit: more important thoughts on the matter in a detailed political perspective in Italy - A New York Times article develops more extensively what I wrote here.

https://www.nytimes.com/2024/08/01/world/olympics/boxer-quits-gender-angela-carini-imane-khelif.html?smid=threads-nytimes

Edit 2: Imane Khelif spoke against cyberbullism.

Edit 3: Since in those past days we talked a lot about cis women being called men for not meeting western TERFs standard, I should resurface this old post about how a group of Chinese cis runners were wrongfully called "men" by TERFs.

Edit 4: Elon Musk and J.K. Rowling have been named in the cyberbullying lawsuit filed by Olympic champion Imane Khelif.

Edit 5 - 13th Sept. 2024: Imane Khelif interview

Edit 6 - 13th Sept. 2024: Imane Khelif won gold medal in boxing. Appreciation post.

[lordmushroomkat]

《The strong association of PCOS with cis womanhood, the defining of it as a disorder or syndrome, and its framing as a “women’s health issue” obscures the fact that PCOS is a natural hormonal variation, an endocrine difference that is illustrated through secondary sex characteristics. 

During my initial search for resources and community, I also learned that PCOS, given its characterization as a hormonal variance, falls under the intersex umbrella. This intersex umbrella covers a wide range of “individuals born with a hormonal, chromosomal, gonadal or genital variation which is considered outside of the male and female norms,” and PCOS meets that definition. 

This is not an attempt to sway every person who has PCOS to identify themselves as intersex—though it is an acknowledgment that we have the option and the right to do so if it rings true to us. Rather, this is to say that shifting my perspective on PCOS and viewing it through an intersex lens allowed me to better understand it as a natural human variation rather than an affliction causing my body to do the “wrong” thing. 

“I believe that someone with PCOS has every right to use the term intersex for themselves if they want, but I also understand it if they don’t,” said writer and intersex advocate Amanda Saenz.

“As an advocate and an intersex person, I opt to use a definition of intersex that is open ended and expansive,” Saenz explains. “The experiences that a term like ‘intersex’ hopes to define include differences in hormonal production and hormone reception, and the phenotypic effects these differences have on the body. To me, this is inclusive of things like PCOS.”

Discussing PCOS in this way is often met with indignation and resistance. Our society has a hard time separating gender from sex. This has resulted in a widespread misunderstanding of intersex identity as equivalent to transgender identity. Many who vehemently resist the idea of PCOS being under the intersex umbrella do so because they categorically link “female” with “woman,” and therefore misinterpret any acceptance of intersex identity as a denial of womanhood. Moreover, the stigma around and marginalization of intersex communities prevents many people from feeling comfortable with embracing it. 

“You can be intersex and cisgender, transgender, or nonbinary. The ‘opposite’ of intersex is endosex, not cisgender,” explained Eshe Kiama Zuri, founder of U.K. Mutual Aid. As a nonbinary intersex person, Zuri approaches these ideas with a clear understanding of how the bodies of intersex individuals as well as many people with PCOS interrupt binary thinking about both sex and gender. 

“The resistance to PCOS falling under the intersex umbrella is due to a white supremacist society’s desperation to cling to binary genders, which we know [have been] used as a colonial tool of control,” they offer. 

The same medical and surgical interventions that legislators seek to ban trans and nonbinary people from accessing—which would be gender-affirming, life-saving care for them—are often forced on intersex infants and children who are unable to consent. This is done in efforts to align intersex bodies with social expectations of female and male, man and woman; the same logic undergirds the societal and medical pressure to “feminize” the female-assigned bodies of PCOS patients. 

PCOS is “shockingly common [and] the most frequently occurring hormone-related disorder.” However, according to Medical News Today, “up to 75% of [people] with PCOS do not receive a diagnosis for their condition.” If we were to understand and accept something like PCOS as intersex, considering how “shockingly common” it is, the dominant idea of binary sex, with intersex being thought of as nothing more than a fringe occurrence, would be shattered. 

“PCOS is only one of many conditions that could fall under the intersex umbrella, and care for people with PCOS would be considerably better if it wasn’t for the forced gendering and resistance to providing actual support for people with PCOS, even if it challenges society’s ideas of gender,” says Zuri. 

Combating myths built around the gender and sex binaries would create more space to understand PCOS traits as part of normal human variation, rather than inherent problems to be fixed, symptoms to be eradicated. As Zuri so beautifully put it, “When we start to accept that this is not a body behaving ‘wrong’ and it is just a body, we stop blaming and punishing people for how their bodies work and start challenging societal expectations.”》

I was fucking right!

[lelouch]

we all know this but these people NEVER cared about "women's sports" or "protecting women", they just want to use cis women as an excuse to be as bigoted as they want, saying bullshit like "woman= human female with xx chromosomes" but the second they see a cis woman with an endocrine disorder their metric magically disappears... would it be because they just weaponize bioessentialist rhetoric to be transmisogynistic? 🤔

non-white cis women specially also get the same treatment bc of different traits like body hair, like this cis Jewish woman called a man for her looks by supposed women's rights defenders and Caster Semenya getting banned from competing for being intersex are proof they don't give a shit and that bioessentialism is bullshit white supremacist rhetoric that only benefits an extremely low percentage of the population

[hiiragi7]

Wondering why PCOS is not considered medically to be under the CAH umbrella (since CAH is a group of conditions involving hyperandrogenism), does anyone happen to know the reason?

Is it the vagueness regarding the cause of PCOS, is it the amount of misunderstanding and misinformation surrounding PCOS, is it intersexism and misogyny? Or even a combination of these?

Looking at the literature, PCOS is indistinguishable from CAH without extensive bloodwork, and often CAH is misdiagnosed as PCOS due to less widespread knowledge of not only CAH's existence (despite it being extremely common) but also due to doctors rarely ever testing for anything that is not 21-OHD, if they decide to run tests at all. (Many PCOS patients are diagnosed without any tests or with only an ultrasound to check for ovarian cysts, which is not actually useful as any kind of evidence towards a PCOS diagnosis at all)

In fact, 3bHSD CAH at one point was even considered to be a type of PCOS rather than CAH. If the two are so similar, and CAH is already an umbrella term, why the distinction between PCOS and CAH at all?

If it's due to treatment implications, that doesn't seem to work because treatment implications are different even within different variations within the CAH umbrella and even further within the same CAH variation. My treatment needs and goals are different from someone with another CAH enzyme deficiency, because the location of the deficiency on the steroid pathway changes a lot about what your symptoms are and how to manage it. Someone with 3bHSD CAH may build up pregnenolone, while someone with 21-OHD CAH may build up progesterone, for example, and these can cause very different outcomes for physical health and needs. There's also vastly different implications between classic, non-classic, and salt-wasters.

Us all being lumped under CAH has never stopped us from accessing the different treatment we need for whichever variation we have. Being grouped under an umbrella label does not mean we are all suddenly the exact same and have the same needs. This is true across all umbrella diagnoses and across spectrum disorders, and CAH is not any different.

A person with XY chromosomes and 3bHSD CAH may have ambiguous genitalia while a person with XX chromosomes and 3bHSD CAH may have completely "typical-appearing" or only slightly virilized genitals, some people with CAH may be infertile while others have no issues with fertility, some have ovarian cysts and some do not, some will go through "typical" puberty and others will have ambiguous or "opposite-sex" puberty, so on.

What vast amount of differences are there between PCOS and CAH that are not present between 21-OHD and 3bHSD, 11-beta, and StAR? PCOS and NCAH can even be more alike to each other than CAH variations can be to other CAH variations.

When we have studies which struggle to differentiate PCOS from CAH even on a biochemical level, why are we so confident in saying that PCOS is not yet another CAH presentation, or that it does not belong underneath that umbrella?

TERFs don't touch this post, I don't want to hear your shit today.

[omegaversetheory]

Assuming that the A/B/O labels are based in genetics, I Wonder if you have any headcannons for genetic disorders?

In my AU, I like to imagine that some people usually believe that persons who have an "extra alpha chromosome" or an "extra omega chromosome" are blessed because they would be like "super alphas" or "super omegas" due their increased capacities when it comes to strenght, size, fertilitie...when in reality they are only partially true.

Sure, those "super alphas and omegas" are more "powerful" when it comes to these característics, but overall, they arent sacred individuals nor super heroes or nothing like that, they are chronically ill people that usually present a lot of health complications that in most cases overcomplicates their daily lives or even can shorten their lifespans (for example, said "super omegas" would be way smaller than the average omega, which usualy leads to frequent bone pains due the incorrect development and consequent malformation of their bones) I also imagine said "super alphas and omegas" being very prone to suffer mental illnesses since the massive amount of hormones they segregate would make them turn into very problematic individuals in general (for example making omegas to be extremely volatile and emotionally irrational individuals, or alphas to have a weird mix between a higly stoic nature and maximized protection instincts, causing them to either become toxic/ manipulative or directly psychopats)

Hi!

What an interesting idea. In my au, well I've never thought about it, but I'd also say that they would be ill, if not extremely chronically ill, people. Depending which age you're writing in, I'd venture to guess there just may not be many of these people around - they would've died very young without the proper medication and constant treatment. That also leads into a larger scientific question about how many chromosomes people in omegaverse have and how exactly their genetics operate. A conversation I'd need a much better grasp of biology and genetics to answer! So I leave it "behind the curtain" in my au, and in fact it's never come up. But if it does, I'll be sure to post.

My notion that having extra chromosomes may result in chronic illness is based on the idea that they probably have more chromosomal pairs or some other genetic system - one that would make the extra material very unlike the human world. Here we see trisomy - which leads to conditions like Down Syndrome. People with DS can now live very fulfilling and rich lives, but it wasn't always that way and it still isn't smooth sailing for many.

I don't use the "super powered" "ultra alpha/omega" headcanons in my au but let's see what we can whip up for you.

It gives the bearer a stronger scent and a better ability to interpret other people's scents.

Decreases fertility and ability to reproduce

Longer heats/ruts that are more intense emotionally/mentally and may cause pain like cramping, migraines, and nose bleeds.

May cause allergic reactions to foods, natural products, etc... This is a common sign (besides infertility) of the condition. Common allergies include - dairy, wheat, some meat products, and nightshades. Some bearers may also have allergic reactions to biological fluids and substances that are not their own including saliva and other natural lubricants.

Have a slightly higher endurance.

[iiyarada]

Been locked in on Frology and trying to figure out which intersex condition he may have. There are ~40 types of intersex conditions and all of them are vastly different in how they affect people.

That said, I've narrowed it down to him most likely having Klinefelter Syndrome (47 XXY) which is where someone is born with an extra copy of the X chromosome.

Frol hits many, if not all of the symptoms of Klinefelter Syndrome. Those symptoms being:

Physical: taller stature, reduced muscle tone, lack of facial and body hair, structural genitourinary abnormalities, enlarged and/or extra breast tissue

Behavioral: Difficulty expressing thoughts and/or feelings, emotional immaturity, mild executive functioning impairment, depression, ADHD

** @motohagios pointed out that Frol is surprised when he finds Tada is taller than him, implying that he isn't considered short in his planet at all. Hence why I am counting that as a symptom he (possibly) hits. A few I can't count, such as depression (he shows no signs), and speech delay (we didn't see Frol's childhood, so it's up in the air) and maybe one or two others, but he still hits a LOT of the symptoms.

One of the most common treatments for Klinefelter Syndrome is testosterone replacement therapy, which is what Frol's parents had planned for him once he returned to his home planet.

On top of all of the signs in the actual manga, in the real world, Klinefelter is the most common sex chromosome disorder. When you look up intersex conditions, chromosome disorders, things along that line, Klinefelter Syndrome is one that commonly pops up. Ans in the 60s and 70s, research published on Klinefelter Syndrome saw an increase, making it plausible that Moto Hagio could have very feasibly came across said research, assuming she researched at all. Which I am inclined to believe, given how well Frol is written from the perspective of an actual intersex person. I find it hard to believe that she could bullshit her way through writing Frol so well without at least SOME research.

Out of all the intersex conditions, Klinefelter Syndrome seems to be the one most in line with Mr Frolbericheri and therefore is the condition I believe he has!!

[intersex-support]

Hello!

I saw the previous ask about Hypogonadism and I was wondering if Hypogonadism could occur without being related to other intersex variations (Chromosome related) BUT also not be cause by other outside factors (Like cancer, medicine, diet, stress I guess?)

Like is it possible for the gonads to just have formed wrong? (I'm referring to Primary Hypogonadism in this case)

Hi anon!

So there are a variety of factors that can cause primary hypogonadism outside of some of the intersex variations we've been discussing on the blog today (such as Klinefelters, Turners, Kallmanns), and also aren't things like environmental risk factors, diet, etc. This article mentions that undescended testicles that are never treated could cause primary hypogonadism. This article explains that fragile X syndrome and galactosaemia are two examples of other conditions that can cause hypogonadism. (There are also a lot of factors that can sometimes cause primary hypogonadism such as cancer treatment, hemochromatosis, mumps, and also normal aging, as well as factors that can sometimes cause secondary hypogonadism, such as HIV, Pituitary disorders, certain medications, malnutrition, and stress).

Beyond that, what I think you might be curious about is gonadal dysgenesis, which is essentially a term for when gonads develop atypically or don't develop at all, and is associated with a wide variety of presentations of symptoms, including chromosomal variations, hypogonadism, and various reproductive structures. There are many different intersex variations associated with gonadal dysgenesis, and there are a lot of different ways that gonadal dysgenesis shows up, but it can potentially cause disruptions in ovarian or testicular or ovotestes function. There's some case studies out there exploring different intersex people's experiences with hypogonadism with gonadal dysgenesis.

So basically, long answer is yes, atypical gonadal development is potentially a cause of hypogonadism for some people!

Hope that helped, anon!

[thefocusfoundation]

The Best Treatment Options For Chromosomal Abnormalities

https://thefocusfoundation.org/ - The Focus Foundation is a research-based agency dedicated to identifying & assisting families & children who have Sex Chromosome Disorders, Dyslexia, and Developmental Dyspraxia. They provide the Best Treatment For Chromosomal Abnormalities.

[weezeryuri]

i highly recommend reading more into cases of fatal neglect and remembering those who died for the crime of simply existing. there were parents who looked upon these faces and decided they were too much of a burden to be allowed to have the bare minimum to survive

Braelyn’ Hines, aged 3, succumbed to neglected cystic fibrosis. she loved pizza and cocomelon and her two kittens, yoda and lucy

King Dewey, aged 3, a boy with autism and suspected Down syndrome who was left to starve in a closet. there is unfortunately no further information about his interests or personal life.

Jaxson Morrow, aged 8, an autistic boy who spent his life locked away in a room. no further info.

Amora Lou Milbourne, aged 3, a young girl with born with chromosome depletion and developmental disorders, left alone in a car to die from heatstroke. no further info.

Morgan Moore, aged 17, a young transgender man suffering from multiple sclerosis, diabetes and long covid. he was unable to walk and forced to live in a disgusting home with no medical treatment and was found dead weighing 79 lbs. he was an artist, self-taught guitarist, cook and keyboard player. he had plans to travel to Japan with his siblings.

Kadaris Maddox, aged 13, a young boy with cerebral palsy left to starve by his mother. His grandmother describes him as having had eyes like rays of sunshine and that he loved everything.

[identitty-dickruption]

Hello, I'm very sorry to bother you. I am about to ask a long and possibly ignorant question. If you don't feel comfortable answering or you simply don't want to (it isn't your job to educate other people, I know that) I totally understand it. Just know that I'm coming from lack of knowledge, not lack of respect.

I just saw this post (couldn't find the original one, sorry) and I wanted to clarify. What exactly do you mean intersex people shouldn't been brought up during debates about gender and sex? I'm not saying you're wrong, I'm just saying that I don't understand.

Everything else in the post, I'm clear about, but when transphobos say shit like "you are biologically either a man or a woman and you cannot change that because you cannot change your chromosomes," I do consider it worth mentioning that biological sex isn't as easy of a topic as they think it is. Human bodies are not always clearly, unquestionably either male or female. And sometimes a person is sure she is clearly, unquestionably female and then, one day when she's 25 years old, she takes a sex verification test for the Olympics and turns out she has XY chromosomes, like María José Martínez Patiño, so chromosomes clearly are a lame excuse for transphobos to use. I'm not gonna give more examples because you probably have heard many at this point and I'm sure you understand intersex topics better than I do, but I think I made clear my point.

If we don't expect all intersex people to live as multigender or nonbinary, then why would someone expect all perisex people to live only as their agab, when we know that everything regarding biological sex (chromosomes, gonads, reproductive system and hormonal production) means nothing when we talk about gender identity?

Again, I'm not trying to say that you're wrong, I just want to understand. Why using an argument like this would be wrong?

hello. out of all the points on that post, this is the one I get challenged on the most, for exactly the points you make — biological sex isn’t binary, it’s bimodal, so talking about intersex people makes sense to a lot of people when they enter these debates. I stand by what I said though

firstly. TERFs, on the most part, don’t see intersex people as intersex. they already have a standard response to this and it’s, “those people just have disorders of sex development, they’re still predominantly either male or female”. TERFs know the cases of intersex athletes very well, and they have ways to talk around it. so, like. this argument doesn’t even work nine times out of ten. it just forces intersex people to see yet more people label them as defective for the sake of a debate

secondly, being used as a gotcha in debates is a microaggression when you consider that it’s usually the only time I see people talk about me and my community. dyadic queer people + allies will acknowledge intersex people exist so they can win a debate, and then never talk about us or think about us again

this is particularly true when these same people will make incredibly intersexist arguments within the same debate

they’ll say things like “nobody’s forcing HRT onto children!” when hi! that happens to intersex kids and teens all the time. they’ll say “cis kids with hormonal disorders get approval for HRT, what’s the difference?” when, again. we’re not “cis kids with hormonal disorders”, we’re intersex people who are forced into unwanted medical treatment all the time

I don’t want my existence used as a debate point if you’re only going to think about me when you can frame it as a zinger or a takedown. I don’t want support because of my position in “the trans debate”, I want support because people actually care about me and my struggles

[dailyunsolvedmysteries]

The Bhopal Tragedy

On the night of December 2nd, 1984, a Union Carbide plant in Bhopal, India, began leaking 27 tonnes of the deadly gas methyl isocyanate. None of the six safety systems designed to contain such a leak were operational, allowing the gas to spread throughout the city of Bhopal. Half a million people were exposed to the gas and 25,000 have died to date as a result of their exposure. More than 120,000 people still suffer from ailments caused by the accident and the subsequent pollution at the plant site. These ailments include blindness, extreme difficulty in breathing and gynaecological disorders. In the Immediate aftermath, the health care system immediately became overloaded. In the severely affected areas, nearly 70% were under-qualified doctors. Medical staff were unprepared for the thousands of casualties. Doctors and hospitals were not aware of proper treatment methods for MIC gas inhalation. There were mass funerals and cremations. Within a few days, trees in the vicinity became barren, and bloated animal carcasses had to be disposed of. 170,000 people were treated at hospitals and temporary dispensaries, and 2,000 buffalo, goats, and other animals were collected and buried. Supplies, including food, became scarce owing to suppliers' safety fears. Fishing was prohibited, causing further supply shortages. Formal statements after a few weeks were issued that air, water, vegetation, and foodstuffs were safe, but people were warned not to consume fish. The number of children exposed to the gases was at least 200,000. Within weeks, the State Government established a number of hospitals, clinics, and mobile units in the gas-affected area to treat the victims.  A cohort of 80,021 exposed people was registered, along with a control group, a cohort of 15,931 people from areas not exposed to MIC. Nearly every year since 1986, they have answered the same questionnaire. It shows excess mortality and morbidity in the exposed group. Bias and confounding factors cannot be excluded from the study. Because of migration and other factors, 75% of the cohort is lost, as the ones who move out are not followed. A number of clinical studies are performed. The quality varies, but the different reports support each other. Studied and reported long-term health effects are: Eyes: Chronic conjunctivitis, scars on cornea, corneal opacities, early cataracts Respiratory tracts: Obstructive and/or restrictive disease, pulmonary fibrosis, aggravation of tuberculosis and chronic bronchitis Neurological system: Impairment of memory, finer motor skills, numbness, etc. Psychological problems: Post traumatic stress disorder (PTSD) Children's health: Peri- and neonatal death rates increased. Failure to grow, intellectual impairment, etc. Missing or insufficient fields for research are female reproduction, chromosomal aberrations, cancer, immune deficiency, neurological sequelae, post traumatic stress disorder (PTSD) and children born after the disaster. Late cases that might never be highlighted are respiratory insufficiency, cardiac insufficiency (cor pulmonale), cancer and tuberculosis. Bhopal now has high rates of birth defects and records a miscarriage rate 7x higher than the national average. The site has never been properly cleaned up and it continues to poison the residents of Bhopal.

[black-paraphernalia]

We at *BP family in the pass post a story of Mrs Henrietta Lacks story and how she and her family for generation were robbed by the scientific community for decades. The most important information to take away is that a single BLACK WOMAN DNA has contributed to modern medical breakthroughs and cures, and is still ongoing. There are a myriad of scientific developments due to Mrs Lacks -HELA CELLS as them called it. We are please to see that the family is getting restitution and reparations from yet again being robbed by them and covering up as them taken the credit and leaving the Black community/family in the dark and high and dry. We will reblog the original post.

ONCE AGAIN A BLACK WOMEN IS THE MOTHER OF INVENTION

(The above is a *BP* commentary opinion)

BLACK PARAPHERNALIA DISCLAIMER - PLEASE READ

Family of Henrietta Lacks settles lawsuit with biotech giant, lawyer says

The family of Henrietta Lacks, a Black woman whose cancer cells were used without permission to form the basis of decades of scientific research, has reached a settlement with the biotech company Thermo Fisher Scientific.

The cells, known as HeLa cells, were taken from Lacks without her knowledge or consent in 1951 when she was seeking cervical cancer treatment at Johns Hopkins, in Baltimore. Doctors discovered that the cells doubled every 20 to 24 hours in the lab instead of dying. They were the first human cells that scientists successfully cloned, and they have been reproduced infinitely ever since.

Lacks herself died in 1951, but her cells continued to be used after her death in research that led to a series of medical advancements, including in the development of the polio vaccine and in treatments for cancer, HIV/AIDS, leukemia and Parkinson's disease. Lacks' family only found out about it decades later.

Lacks' story reached millions of Americans through the nonfiction bestseller "The Immortal Life of Henrietta Lacks," which was made into an HBO movie starring Oprah Winfrey as Lacks' daughter, Deborah.

In 2021, Lacks' estate filed a lawsuit against Thermo Fisher Scientific, alleging that the company was mass producing and selling tissue taken from Lacks even after it became well-known that the materials had been taken from her without her consent. The suit was filed exactly 70 years after Lacks' death.

"Thermo Fisher Scientific has known that HeLa cells were stolen from Ms. Lacks and chose to use her body for profit anyway," the lawsuit alleged. It has been previously reported that Thermo Fisher Scientific said they generate about $35 billion in annual revenue. In the lawsuit, Lacks' estate asked that the company "disgorge the full amount of its net profits obtained by commercializing the HeLa cell line to the Estate of Henrietta Lacks."

The suit also sought an order stopping the company from using the HeLa cells without the estate's permission. The terms of Tuesday's settlement were not made public, but Crump said in a news conference that both parties were "pleased" to have resolved the matter outside of court, CBS Baltimore reported. (except taken from KERRY BREEN CBS NEWS , 2023 )

INFORMATION OBTAIN FROM NATURE.COM FOR MORE READ CLICK HERE

SOME CONTRIBUTIONS OF THE HELA CELLS

-HeLa cells were first used to study the growth and spread of poliomyelitis virus, the cure of Polio

-HeLa cells have also been instrumental in the development of Human papilloma virus (HPV) vaccines.

-Over the years, HeLa cells have been infected with various types of viruses including HIV, Zika, herpes, and mumps

-HeLa cells have been used in a number of cancer studies, including those involving sex steroid hormones such as estradiol, estrogen, and estrogen proliferation.

-Hela cells contribute to scientists Joe Hin Tjio and Albert Levan to develop better techniques for staining and counting chromosomes.This was important for the study of developmental disorders such as down syndrome that involved the number of chromosomes.

-HeLa cells were sent on the first satellite and human space missions to determine the long term effects of space travel on living cells and tissue.

-HeLa cell line was derived for use in cancer research. and human papillomavirus 18 (HPV18) to human cervical cells created the HeLa genome, which is different from Henrietta Lacks’ genome in various ways,

-The complete genome of the HeLa cells was sequenced and published on 11 March 2013[46][47] without the Lacks family’s knowledge

-HeLa cells as a tool to uncover the machinery required and process used for invasion of human cells. Researchers have also investigated the stability of the virus’s genomic material in HeLa cells by comparing its genomic material with that of many other viruses. The use of HeLa cells in COVID-19 research has provided insights on the molecular mechanics of SARS-CoV-2019 and the components required for infection.

INFORMATION OBTAINED HERE

A LASTING CONTRIBUTION TO THE WORLD

When Henrietta Lacks and her cells alerted the world to the existence of immortal human cells, opportunities arose for research and medical treatment development.

Today, her cells continue to serve academic and industrial institutions. So much so that she has been described as the Mother of Modern Medicine in a painting by artist Kadir Nelson in 2017.

The use of HeLa cells in COVID-19 research is a testament to Henrietta Lacks’s lasting contribution to provide microscopic tools for scientific discoveries that billions have benefitted from thus far and will benefit from in the future to come.

INFORMATION OBTAIN FROM NATURE.COM FOR MORE READ CLICK HERE

SOME CONTRIBUTIONS OF THE HELA CELLS

-HeLa cells were first used to study the growth and spread of poliomyelitis virus, the cure of Polio

-HeLa cells have also been instrumental in the development of Human papilloma virus (HPV) vaccines.

-Over the years, HeLa cells have been infected with various types of viruses including HIV, Zika, herpes, and mumps

-HeLa cells have been used in a number of cancer studies, including those involving sex steroid hormones such as estradiol, estrogen, and estrogen proliferation.

-Hela cells contribute to scientists Joe Hin Tjio and Albert Levan to develop better techniques for staining and counting chromosomes.This was important for the study of developmental disorders such as down syndrome that involved the number of chromosomes.

-HeLa cells were sent on the first satellite and human space missions to determine the long term effects of space travel on living cells and tissue.

-HeLa cell line was derived for use in cancer research. and human papillomavirus 18 (HPV18) to human cervical cells created the HeLa genome, which is different from Henrietta Lacks’ genome in various ways,

-The complete genome of the HeLa cells was sequenced and published on 11 March 2013 without the Lacks family’s knowledge

-HeLa cells as a tool to uncover the machinery required and process used for invasion of human cells. Researchers have also investigated the stability of the virus’s gnomic material in HeLa cells by comparing its genomic material with that of many other viruses.

The use of HeLa cells in COVID-19 research has provided insights on the molecular mechanics of SARS-CoV-2019 and the components required for infection.

INFORMATION OBTAINED HERE

A LASTING CONTRIBUTION TO THE WORLD

When Henrietta Lacks and her cells alerted the world to the existence of immortal human cells, opportunities arose for research and medical treatment development.

Today, her cells continue to serve academic and industrial institutions. So much so that she has been described as the Mother of Modern Medicine in a painting by artist Kadir Nelson in 2017.

The use of HeLa cells in COVID-19 research is a testament to Henrietta Lacks’s lasting contribution to provide microscopic tools for scientific discoveries that billions have benefitted from thus far and will benefit from in the future to come.