#Cholera Vaccine

[civilmentor1]

Current affairs - 30 August 2024

1.Oral Cholera Vaccine (Hillchol) The Hindu Background: Bharat Biotech, in collaboration with Hilleman Labs, has launched Hillchol (BBV131), an oral vaccine for cholera. Global Demand: The vaccine aims to address the global shortage of Oral Cholera Vaccines (OCVs), with a demand exceeding 100 million doses per year. Dosage: Hillchol is administered in two oral doses. Clinical Trials: Phase…

[thoughtlessarse]

There are no more oral cholera vaccines left in the global stockpile, the World Health Organization (WHO) said Friday, with the shortage jeopardising work to stop the disease’s spread. Global vaccine production is operating at full capacity, but demand is outpacing supply, the United Nations (UN) health agency said in its monthly situation report. “As of October 14, the global stockpile of oral cholera vaccine is depleted, with no remaining doses available,” the WHO said. “Although more doses are expected in the coming weeks, this shortage poses significant challenges to outbreak response efforts and hampers efforts to control the spread of the disease.” The WHO said that between September 1 and October 14, the International Coordinating Group on vaccine provision received requests for oral cholera vaccines from Bangladesh, Sudan, Niger, Ethiopia and Myanmar.

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[lasseling]

The DTP Vaccine Lots: Thousands of Children Injured by Highly Toxic Formulas Containing Cholera Antigens

A recent investigation into vaccine manufacturing processes has revealed that not all vaccine lots are created equal.

[clairyclue]

i fear i need to be marcella in ragdolly

[toytulini]

god im not starting shit on the post but "medical and pharmaceutical companies thank you for your long term patronage" really does not work as a thing to shame anti maskers. this is not a system i get to opt out of even by masking. unfortunately, i really dont think masking is pwning the predatorily priced healthcare system in the usa. especially considering how many of the ppl who are still doing it are unfortunately beholden to it anyway for some other fucking reason. fuck, even if i didnt have medications i take everyday anyway, the company i buy n95s from is a fucking medical /surgical supply company? its such a weird. just. no.

[kweza]

looking at my old vaccination booklet for HR stuff at work and i really got vaccinated for things i don't even know exist. what the heck

[ophilosoraptoro]

Bill Gates alerts next pandemic as W.H.O. warns Cholera could be next

They sure like to snitch on themselves.

Might wanna invest in water purification though.

[volixia669]

I...What.

Why the fuck the 1830s? "But without the racists" Okaaaaaaaaay, even if we set aside all the other bigotries alive and well, that's still a very simplified way of looking at slavery, white supremacy, and colonialism.

Also if the song isn't about those topics, that I'm sure she doesn't give a fuck about, why bring up racism at all? It just sounds like the songwriter was like "oh right the 1830s had slavery, let's just rhyme this with racists aaaaannnd perfect." Which again, whyyyyy the 1830s?

One thing is for sure, I'm still side eyeing my cousin who ADORES Taylor Swift and thinks her music is the best thing ever.

i can't believe this is real this sounds like it was pulled directly from the "i wanna have straight sex" tiktok

[chronicillnesscaneffoffplease]

Advantages to being in the tropics:

My joints are pretty happy with the humidity- yay less pain on the daily!

My nails are growing ridiculously fast I feel.

Dry skin issues (nose, ear, hands) have cleared up. Yay moisture!

I’ve been pretty lucky re migraines so far.

Food has also been working out okay. Which is good. More meat than I usually eat, but I’m doing okay. Lot of soft fruit which is divine.

Disadvantages:

You know you drink a lot of water. But when all you can drink is bottled water you get a pretty ah, visual representation of how much you’re really drink by the waste you leave behind. It’s a looooot of water bottles. We keep leaving these little “water bottle graveyards” in our room.

It’s hot. Humid. My pots has been a little fussy, and I’ve upped my am meds to give me a bit of a better chance. Get a bit woozier than normal, but not having as bad a time as I thought.

Sweating like a pig with ASF (African swine fever). About as pink as one, too.

Swollen legs most days with blood/fluid pooling. Bit irritating. I do have compression socks I should be wearing,,,, but hooooootttttt.

Sunburn (my own fault). Needed to remember that being on photosensitising meds means to cover up more, despite sunscreen, even if the singlet feels cooler. Between covering up, umbrella, and spf 50 I’ve not had a repeat incident.

A few mozzie and bug bites, but really not that bad.

On the whole I’m having a great time. Yes it’s a little tricky and yes it’s a bit uncomfy but it’s so much fun and I’m learning a lot.

[head-post]

Zambia, China signed MoU to establish African country’s first cholera vaccine plant

Zambia signed a Memorandum of Understanding (MoU) with China to build the South African country’s first cholera vaccine manufacturing plant.

The first phase of the project, signed on Monday, is worth $37 million. About three million doses will be produced through a joint venture between Zambia’s Industrial Development Corporation (IDC) and Jijia International Medical Technology Corporation.

Zambian President Hakainde Hichilema said the development was a key step in the country’s efforts to eradicate the disease.

We are also sending a signal that Zambia, Africa and the globe are able to work together. Zambia must be looked at as a center, as a location to manufacture for a bigger market. And if you look at the population of Africa, it is growing very rapidly.

Hichilema expects the project to be commercially viable. There was no room for bureaucracy in its implementation as it would save lives, he added.

China will donate about three million doses of cholera vaccine before production begins. This is a year-round disease across the southern African country, especially during the rainy season. Although it can be cured, it remains deadly.

Read more HERE

[privatemedicalclinic]

Cholera Vaccines in Watford

Cholera is caught after eating or drinking food, drink or water contaminated by a bacteria.

Know more: https://www.privatemedical.clinic/cholera-dukoral-vaccination

[beauila-blog]

Cholera Deaths Surge Globally Despite Being Preventable

Cholera, a disease long known to be easily preventable, has seen a dramatic increase in fatalities worldwide, with deaths rising by 71% in 2023, according to a World Health Organization (W.H.O.) analysis. The number of reported cholera cases only increased by 13%, signaling that outbreaks are becoming deadlier, largely due to overwhelmed health systems, conflict, and climate change.

Though cholera can be treated with basic and inexpensive interventions like oral rehydration salts, huge outbreaks in countries unaccustomed to handling the disease have stretched health infrastructure to the brink. Philippe Barboza, head of the W.H.O.’s cholera emergency response, called the sharp rise in deaths “totally unacceptable.”

“It reflects the world’s lack of interest in a disease that has plagued humans for thousands of years, afflicting the poorest people who cannot find clean water to drink,” he said.

In 2023, more than 4,000 cholera deaths were officially reported, but the actual toll could be as high as 100,000, according to the W.H.O.'s estimates based on testing data.

A Disease That Should Be Easy to Stop

Cholera causes severe dehydration as the body attempts to expel the bacteria through vomiting and diarrhea, and without timely treatment, it can be fatal within 24 hours. The solution? Basic treatments, like a simple bag of oral rehydration salts, which cost as little as 50 cents, along with IV fluids and antibiotics. Yet many people die without access to such care.

In 2023, cholera outbreaks were reported in 45 countries, up from 35 in 2021. Much of the burden has shifted to Africa, where cases surged by 125% last year, driven by catastrophic weather events such as floods and droughts, which exacerbate the spread of waterborne diseases.

Countries like Zambia and Malawi, though proactive in their responses, saw their health systems pushed to the limits. Lusaka, Zambia's capital, had to repurpose a stadium into a cholera treatment center. Meanwhile, in Sudan, ongoing civil conflict has displaced over nine million people, creating cramped living conditions in camps with poor sanitation. Despite efforts to control a cholera outbreak in Sudan last year, the disease has returned, with over 5,600 new cases reported since mid-August.

Deadly Community Spread and Overburdened Health Systems

One of the key reasons for rising fatalities is the increase in "community deaths," where people succumb to cholera without ever reaching a health facility. This has been a particular problem in large countries with weak cholera surveillance, like India, which reports very few cases relative to its population. Bangladesh, in contrast, has made significant strides in tracking and reporting cholera cases, accounting for over 23,000 cases in 2023, though much of this reflects improved detection rather than worsening outbreaks.

The W.H.O. recorded over 535,000 cholera cases worldwide in 2023, a rise from 472,000 in 2022. Countries like Afghanistan, Haiti, and Mozambique have also reported very large outbreaks, each with more than 10,000 confirmed or suspected cases, more than doubling the number of such massive outbreaks from previous years.

Vaccine Shortages Worsen the Crisis

The cholera crisis has been aggravated by a global shortage of vaccines, with demand outpacing supply for years. Vaccines are primarily targeted at low- and middle-income countries, where they sell for as little as $1.50 per dose. The International Coordinating Group, which manages the global emergency cholera vaccine stockpile, recommended a shift to a single-dose strategy to stretch supplies. However, even this measure has proven insufficient, with countries requesting 74 million doses in 2023, while fewer than half of those requests were fulfilled.

Rachel Park, international business director for EuBiologics, the sole global supplier of cholera vaccines, said the company is switching to a simplified vaccine formula that will boost production by 40% by the end of the year. Despite this, total supply will still fall short, with only 50 million doses expected to be available next year.

Bharat Biotech, an Indian pharmaceutical company, has developed a new cholera vaccine called HillChol, recently approved for domestic use. The company plans to apply for W.H.O. authorization to contribute to the global stockpile by 2026, with an initial annual production target of 40 million doses.

A Continuing Global Health Threat

As cholera cases continue to climb and vaccine shortages persist, many countries remain at high risk of outbreaks. With weather patterns exacerbating the spread of the disease, particularly in areas lacking adequate sanitation and access to clean water, cholera will continue to pose a significant threat to vulnerable populations worldwide.

Dr. Barboza warned that until global efforts are ramped up to meet the growing demand for vaccines and basic treatments, cholera will continue to claim lives unnecessarily. "How can we accept that people are dying in 2024 because they don’t have access to a simple bag of oral rehydration salts?" he said.

[traveldoc]

Cholera Vaccination

Cholera is an acute diarrhoeal illness caused by a bacteria. The disease infects the small bowel and causes painless, watery diarrhea. It is known to infect only humans.

Know more: https://www.travel-doc.com/service/cholera/

[alabs1]

Cholera Outbreak: Death Toll Hits 40, As Nigeria Runs Out Of Vaccines 

The Nigeria Centre for Disease Control (NCDC) has said that the country does not have enough vaccines for Cholera despite the death toll from the outbreak reaching a record high of 40 as of Friday 2024. The global health body, World Health Organisation (WHO), had announced a spike in cholera in several regions of the world. The United Nations body revealed that there had been a spike in cholera…