#Cholera Vaccine

[civilmentor1]

Current affairs - 30 August 2024

1.Oral Cholera Vaccine (Hillchol) The Hindu Background: Bharat Biotech, in collaboration with Hilleman Labs, has launched Hillchol (BBV131), an oral vaccine for cholera. Global Demand: The vaccine aims to address the global shortage of Oral Cholera Vaccines (OCVs), with a demand exceeding 100 million doses per year. Dosage: Hillchol is administered in two oral doses. Clinical Trials: Phase…

[chronicillnesscaneffoffplease]

Advantages to being in the tropics:

My joints are pretty happy with the humidity- yay less pain on the daily!

My nails are growing ridiculously fast I feel.

Dry skin issues (nose, ear, hands) have cleared up. Yay moisture!

I’ve been pretty lucky re migraines so far.

Food has also been working out okay. Which is good. More meat than I usually eat, but I’m doing okay. Lot of soft fruit which is divine.

Disadvantages:

You know you drink a lot of water. But when all you can drink is bottled water you get a pretty ah, visual representation of how much you’re really drink by the waste you leave behind. It’s a looooot of water bottles. We keep leaving these little “water bottle graveyards” in our room.

It’s hot. Humid. My pots has been a little fussy, and I’ve upped my am meds to give me a bit of a better chance. Get a bit woozier than normal, but not having as bad a time as I thought.

Sweating like a pig with ASF (African swine fever). About as pink as one, too.

Swollen legs most days with blood/fluid pooling. Bit irritating. I do have compression socks I should be wearing,,,, but hooooootttttt.

Sunburn (my own fault). Needed to remember that being on photosensitising meds means to cover up more, despite sunscreen, even if the singlet feels cooler. Between covering up, umbrella, and spf 50 I’ve not had a repeat incident.

A few mozzie and bug bites, but really not that bad.

On the whole I’m having a great time. Yes it’s a little tricky and yes it’s a bit uncomfy but it’s so much fun and I’m learning a lot.

[clairyclue]

i fear i need to be marcella in ragdolly

[kweza]

looking at my old vaccination booklet for HR stuff at work and i really got vaccinated for things i don't even know exist. what the heck

[ophilosoraptoro]

Bill Gates alerts next pandemic as W.H.O. warns Cholera could be next

They sure like to snitch on themselves.

Might wanna invest in water purification though.

[usergreenpixel]

Okay, so the comment section is full of debates about whether or not the USSR was a communist or fascist or good or bad country… but let’s not get into that debate here.

(I’m Russian and grew up in Russia. Right now there is a trend of demonizing everything Soviet btw, at least in Russia. I’m not kidding, the government is sponsoring movies that do only the demonization.)

But anyway, that political shit aside, in the 1920s (Soviet Union just got formed and it was after a civil war with the monarchists…) there was a particular demand for PSAs, and not just of the “don’t mingle with the monarchists” variety. A lot of HEALTH PSAs, which makes sense considering that the goal was to spread awareness, especially in smaller communities that were still following some dangerous practices.

(Translation: Only a vaccine will save you from cholera!)

But they weren’t always just images with text telling you to get vaccinated and wash your hands. Back then some PSAs like that were actually poems (quite a lot, actually!):

One second:

Popular art style of the time period btw. This is going to be hard to translate from Russian, but let me try:

Hey, you folks, look over here!

See, one man’s already marred,

That one’s blind forever,

Those two, see? They’re crippled!

If you keep on being careless,

You might become just like them.

To a doctor run, right now

Get a pox vaccine!

Context: This was before smallpox was officially eradicated in the Soviet Union, so the pox referred to here is smallpox. And yes, it could absolutely lead to (at best!) scarring, but it could also leave a person blind or with other “fun” complications. And it was contagious so it was crucial to warn the public about the dangers associated with the disease.

My feelings on the USSR are very complicated, but I think it’s interesting to see how PSAs looked in different decades in that country. Art does reflect a lot of context after all.

love those old soviet posters that are just advertising like, an activity. not some “go to mike’s hardware for the BEST deals around!” just “hey, you can learn stuff at libraries” or “consider going for a hike in the countryside” big kin

[farmerstrend]

Diseases do Not Announce Their Arrival: Understanding and Preventing Poultry Diseases

In poultry farming, diseases pose a silent but ever-present threat to your flock. For most rural poultry farmers, the scourge of disease can lead to devastating consequences, ranging from financial losses to the eventual closure of operations. This article aims to educate poultry farmers on the causes, warning signs, and practical steps to mitigate poultry diseases effectively. The Heavy Cost of…

[sciencesolutions]

[volixia669]

I...What.

Why the fuck the 1830s? "But without the racists" Okaaaaaaaaay, even if we set aside all the other bigotries alive and well, that's still a very simplified way of looking at slavery, white supremacy, and colonialism.

Also if the song isn't about those topics, that I'm sure she doesn't give a fuck about, why bring up racism at all? It just sounds like the songwriter was like "oh right the 1830s had slavery, let's just rhyme this with racists aaaaannnd perfect." Which again, whyyyyy the 1830s?

One thing is for sure, I'm still side eyeing my cousin who ADORES Taylor Swift and thinks her music is the best thing ever.

i can't believe this is real this sounds like it was pulled directly from the "i wanna have straight sex" tiktok

[head-post]

Zambia, China signed MoU to establish African country’s first cholera vaccine plant

Zambia signed a Memorandum of Understanding (MoU) with China to build the South African country’s first cholera vaccine manufacturing plant.

The first phase of the project, signed on Monday, is worth $37 million. About three million doses will be produced through a joint venture between Zambia’s Industrial Development Corporation (IDC) and Jijia International Medical Technology Corporation.

Zambian President Hakainde Hichilema said the development was a key step in the country’s efforts to eradicate the disease.

We are also sending a signal that Zambia, Africa and the globe are able to work together. Zambia must be looked at as a center, as a location to manufacture for a bigger market. And if you look at the population of Africa, it is growing very rapidly.

Hichilema expects the project to be commercially viable. There was no room for bureaucracy in its implementation as it would save lives, he added.

China will donate about three million doses of cholera vaccine before production begins. This is a year-round disease across the southern African country, especially during the rainy season. Although it can be cured, it remains deadly.

Read more HERE

[chronicillnesscaneffoffplease]

The duality of. Yes I am disabled. Yes I am about to go on a fieldwork trip that even abled bodied people would struggle with. Yes today was a bad pain day. Yes I think I’m prepared and I’ll get through it fine. Yes I am going to be exhausted. In fact I am excited for it. Excited to be exhausted from absorbing so many new things about one of my favourite topics, not just the physical effort of daily life. Yes I am well prepared. Yes I’m worrying. Yes I’m being blase about it. Yes I’m looking forward to cool chats with my supervisor. Yes I’m worried she’ll understand my disabled life more now. Yes I’m worried I’ll get overstimulated. Yes I am looking forward to disconnecting. Yes I’m worried about what our routine will be. Yes I’m looking forward to switching it up.

Idk. The duality of knowing I am disabled but I can do epic things with the right planning. Being allowed that dignity of risk. Hitting me kind of hard tonight.

[privatemedicalclinic]

Cholera Vaccines in Watford

Cholera is caught after eating or drinking food, drink or water contaminated by a bacteria.

Know more: https://www.privatemedical.clinic/cholera-dukoral-vaccination

[beauila-blog]

Cholera Deaths Surge Globally Despite Being Preventable

Cholera, a disease long known to be easily preventable, has seen a dramatic increase in fatalities worldwide, with deaths rising by 71% in 2023, according to a World Health Organization (W.H.O.) analysis. The number of reported cholera cases only increased by 13%, signaling that outbreaks are becoming deadlier, largely due to overwhelmed health systems, conflict, and climate change.

Though cholera can be treated with basic and inexpensive interventions like oral rehydration salts, huge outbreaks in countries unaccustomed to handling the disease have stretched health infrastructure to the brink. Philippe Barboza, head of the W.H.O.’s cholera emergency response, called the sharp rise in deaths “totally unacceptable.”

“It reflects the world’s lack of interest in a disease that has plagued humans for thousands of years, afflicting the poorest people who cannot find clean water to drink,” he said.

In 2023, more than 4,000 cholera deaths were officially reported, but the actual toll could be as high as 100,000, according to the W.H.O.'s estimates based on testing data.

A Disease That Should Be Easy to Stop

Cholera causes severe dehydration as the body attempts to expel the bacteria through vomiting and diarrhea, and without timely treatment, it can be fatal within 24 hours. The solution? Basic treatments, like a simple bag of oral rehydration salts, which cost as little as 50 cents, along with IV fluids and antibiotics. Yet many people die without access to such care.

In 2023, cholera outbreaks were reported in 45 countries, up from 35 in 2021. Much of the burden has shifted to Africa, where cases surged by 125% last year, driven by catastrophic weather events such as floods and droughts, which exacerbate the spread of waterborne diseases.

Countries like Zambia and Malawi, though proactive in their responses, saw their health systems pushed to the limits. Lusaka, Zambia's capital, had to repurpose a stadium into a cholera treatment center. Meanwhile, in Sudan, ongoing civil conflict has displaced over nine million people, creating cramped living conditions in camps with poor sanitation. Despite efforts to control a cholera outbreak in Sudan last year, the disease has returned, with over 5,600 new cases reported since mid-August.

Deadly Community Spread and Overburdened Health Systems

One of the key reasons for rising fatalities is the increase in "community deaths," where people succumb to cholera without ever reaching a health facility. This has been a particular problem in large countries with weak cholera surveillance, like India, which reports very few cases relative to its population. Bangladesh, in contrast, has made significant strides in tracking and reporting cholera cases, accounting for over 23,000 cases in 2023, though much of this reflects improved detection rather than worsening outbreaks.

The W.H.O. recorded over 535,000 cholera cases worldwide in 2023, a rise from 472,000 in 2022. Countries like Afghanistan, Haiti, and Mozambique have also reported very large outbreaks, each with more than 10,000 confirmed or suspected cases, more than doubling the number of such massive outbreaks from previous years.

Vaccine Shortages Worsen the Crisis

The cholera crisis has been aggravated by a global shortage of vaccines, with demand outpacing supply for years. Vaccines are primarily targeted at low- and middle-income countries, where they sell for as little as $1.50 per dose. The International Coordinating Group, which manages the global emergency cholera vaccine stockpile, recommended a shift to a single-dose strategy to stretch supplies. However, even this measure has proven insufficient, with countries requesting 74 million doses in 2023, while fewer than half of those requests were fulfilled.

Rachel Park, international business director for EuBiologics, the sole global supplier of cholera vaccines, said the company is switching to a simplified vaccine formula that will boost production by 40% by the end of the year. Despite this, total supply will still fall short, with only 50 million doses expected to be available next year.

Bharat Biotech, an Indian pharmaceutical company, has developed a new cholera vaccine called HillChol, recently approved for domestic use. The company plans to apply for W.H.O. authorization to contribute to the global stockpile by 2026, with an initial annual production target of 40 million doses.

A Continuing Global Health Threat

As cholera cases continue to climb and vaccine shortages persist, many countries remain at high risk of outbreaks. With weather patterns exacerbating the spread of the disease, particularly in areas lacking adequate sanitation and access to clean water, cholera will continue to pose a significant threat to vulnerable populations worldwide.

Dr. Barboza warned that until global efforts are ramped up to meet the growing demand for vaccines and basic treatments, cholera will continue to claim lives unnecessarily. "How can we accept that people are dying in 2024 because they don’t have access to a simple bag of oral rehydration salts?" he said.

[traveldoc]

Cholera Vaccination

Cholera is an acute diarrhoeal illness caused by a bacteria. The disease infects the small bowel and causes painless, watery diarrhea. It is known to infect only humans.

Know more: https://www.travel-doc.com/service/cholera/

[alabs1]

Cholera Outbreak: Death Toll Hits 40, As Nigeria Runs Out Of Vaccines 

The Nigeria Centre for Disease Control (NCDC) has said that the country does not have enough vaccines for Cholera despite the death toll from the outbreak reaching a record high of 40 as of Friday 2024. The global health body, World Health Organisation (WHO), had announced a spike in cholera in several regions of the world. The United Nations body revealed that there had been a spike in cholera…