#Angioedema

[lifblogs]

I’m still so shocked by getting diagnoses for rare conditions this month.

Angioedema, diagnosed first patient appointment with an allergist, testing ordered, treatment spoken of.

Erythromelalgia (I think that’s how you spell it?), diagnosed immediately at my rheumatology follow-up with no beating around the bush, testing ordered to see if there is an underlying cause, treatment started same day.

[medicaregate]

Acquired Angioedema | Causes, Symptoms & Treatments

Acquired angioedema (AAE) is defined as a deficiency in the C1 esterase inhibitor.

It is a rare disorder characterized by recurring angioedema without urticaria that may be linked to lymphoproliferative disorders (LPD).

Acquired angioedema is classified into two types: AAE-I and AAE-II.

AAE results from an acquired deficiency of (C1-INH), which can be caused by consumption (type 1) or inactivation (type 2).

This increased catabolism can be caused by an autoimmune disorder (such as systemic lupus erythematosus) or a malignant tumor (such as lymphoma).

The primary symptom is swelling usually affects the face, mouth, and upper airways which can be severe. Itching and urticaria don’t occur.

Clinicians should suspect acquired C1 inhibitor deficiency or hereditary angioedema if angioedema is not accompanied by urticaria, recurs without apparent cause, or is triggered by local trauma.

Hereditary angioedema (types 1 and 2) or acquired C1 inhibitor deficiency is confirmed by: –

Low C4 levels, even between episodes.

Decreased C1 inhibitor level or function.

Treatment options include: –

Plasma-derived or recombinant C1-INH for acute attacks.

Icatibant which alleviate AAE symptoms and was well tolerated.

Ecallantide is used in the treatment of AAE and is also considered another treatment option for patients who have developed resistance to C1-INH replacement.

Fresh frozen plasma (FFP) may be used if neither of these treatments is available.

Read more at: https://medicaregate.com/acquired-angioedema-causes-symptoms-treatments/

[getyoungersblog]

Full Urticaria Cure Dr. Gary M Levin M.D: A Comprehensive Reviews

This passage discusses the various triggers for Urticaria and Angioedema, including perfume, dust mites, hairspray, nuts, solvents, tight clothing, pressure, cheese, and dogs. The author attributes these reactions to a hyperactive immune system rather than traditional allergies. Dr. Gary's research suggests that Urticaria patients don't experience allergies, but rather their immune system becomes hyperactive when exposed to certain stimuli. The recurrent nature of hives is described as a draining and disheartening condition, causing constant itching, pain, and redness. The text emphasizes the impact on daily life, disrupting focus and vivacity, making it difficult to engage in favorite activities. Idiopathic Urticaria is acknowledged as not inherently destructive, but the persistent discomfort can be exhausting, leading to restlessness and discouragement.

See More about "Full Urticaria Cure" Here!

About Author

The author of the program is identified as Dr. Gary M. Levin, a retired M.D. and Surgeon from the United States. Dr. Levin enjoyed a long career managing his clinic, teaching, and overseeing resident doctors at a Loma Linda University School of Medicine facility. Recognizing the severity of hives and angioedema, he empathizes with individuals who undergo unsuccessful treatments, exhaustive efforts to eliminate potential allergens, and inconclusive allergy testing.

Despite his retirement and the closure of his physical clinic, Dr. Gary M. Levin maintains an effective method for treating hives. Though he no longer has direct patient contact, he is passionate about assisting global hives patients in playing an active role in their treatment. His goal is to guide them in implementing successful practices derived from past patient experiences, promoting a productive and insightful approach to managing and curing their hives.

Click Here to Download PDF "Full Urticaria Cure" eBook by Dr Gary M.D!

About the Program

The product, presented as an audio-book by Dr. Gary M. Levin, offers a natural cure for hives and angioedema. Due to its natural nature, it cannot be patented or promoted through traditional means such as the pharmaceutical industry or pharmacies. Dr. Gary has compiled the findings of his research, experimentation, and trials into a step-by-step guide, claiming that following this guide can lead to the cure of hives and angioedema within 2-3 weeks.

Dr. Gary's involvement in this approach stems from his scientific background, prompting him to dedicate two years to instructing and exploring natural remedies and alternative therapies for various disorders. The audio-book serves as a resource for individuals seeking a natural solution to their condition, aiming to empower them with the knowledge and guidance necessary for a successful recovery. The product is positioned as an alternative to traditional pharmaceutical approaches, emphasizing the limitations of public awareness and understanding when it comes to archives and the ability to discern and adopt new information and therapies.

How Does It Work?

The product claims to have positive effects, with numerous patients reporting being cured of their hives for several years, while others have experienced significant improvements. These testimonials describe a trans-formative impact on the lives of individuals who have regained their smiles, positive, and a sense of a better future without the anxiety and fear of recurring painful hives.

The testimonials are often shared through video stories on the internet, featuring individuals from diverse backgrounds and locations worldwide. To respect privacy, the patients are portrayed by actors, yet their narratives are said to be based on the genuine experiences of real individuals. According to these accounts, individuals credit Dr. Gary's system with freeing them from the challenges of living with hives. As with any health-related product or program, individual results may vary, and it's essential for potential users to exercise discernment and consult with healthcare professionals when considering alternative treatments.

What problem does the product help to solve?

The product is designed to address the problem of hives and angioedema by providing a natural cure based on Dr. Gary M. Levin's research and established procedures. The main issue it aims to solve is the circulation of incorrect information regarding these conditions. Dr. Gary emphasizes the use of tested and proven methods derived from genuine and extensive study and research, which he personally confirmed through working with real patients in his clinic and teaching at a medical facility.

The product acknowledges the uniqueness of each individual's physique, blood type, metabolism, and overall well-being, highlighting that responses to alternative approaches may vary due to these factors. It asserts that while alternate approaches may not be formalized and assessed to the same extent as conventional medicine, it provides a procedure to align the body's chemical processes. The approach involves an easy vitamin routine and a natural drink, claimed by Dr. Gary to be more effective than other hives medications combined and readily available. The overarching goal is to offer a solution to the challenges faced by individuals dealing with hives and angioedema.

Conclusion

In conclusion, the text suggests that relying on regular medications or creams may be unnecessary for relieving the symptoms of hives and angioedema. It emphasizes the importance of identifying and avoiding trigger foods, such as seafood, to prevent outbreaks. However, for those whose quality of life is significantly affected by hives, consulting with a doctor is recommended for therapy and to investigate potential underlying health issues.

The author asserts a bold claim that it is possible to live a life free of hives and angioedema, citing examples of previous patients and those who have successfully utilized the strategies outlined in the audio-book. The text encourages readers to consider the potential benefits of the product, suggesting that today might be the only opportunity to purchase it and stating that the investment is worthwhile.

Click Here to Download eBook "Full Urticaria Cure" PDF by Dr Gary M.D!

[charlie-in-a-beanie]

Potential Angioedema gang wya? 🤠✋

[sukieelizabeth]

So need a smaller better bed, since this sngioedema need something better to sleep on, then maybe I can put a soft chair in my room to sit on

[writer-at-the-table]

The EMS guys and ER staff were so impressed with my little Health Notebook with lists of conditions and medications last night.

I felt like I was getting good grades in Chronic Illness and ER Visit, which is normal to want and possible to achieve

[thechaoticbookwyrm]

Vine Beetles, Disappointment, & Doggie Training.

[comparableau]

Hereditary Angioedema Market is expected to exceed the market valuation of more than US$ XX billion in 2027 and is expected to grow at a significant CAGR of XX% during the forecast period (2021-2027).

[lifblogs]

I’m hungry and anxious about food tomorrow. So my current guesstimate of when it is safe for me to eat is 9:00 AM - 4:00 PM. I have a 9:15 appointment. I get low blood sugar if I don’t eat. AND to make matters worse I have a 3:30 appointment.

So do I have a late breakfast and risk passing out? Or have an early breakfast and risk an allergic reaction/possible anaphylaxis?

Do I have what basically amounts to second lunch and risk being hungry all evening and night and possibly having low blood sugar the next morning? Or do I have a “late” dinner after my appointment and risk a possible allergic reaction/anaphylaxis?

I am so stressed right now.

[cloak-of-ares]

don't be shy [Ares, not knowing how else he can help, continued to fuss like a man]

{open Starter} allergy

(based on a real story aka it happened to me yesterday)

*you wanted to check on Ally, when you saw her she was laying on her bed her lip was swelling up too*

What do you do?

(tags @acezinspace @emdabitchass @urbestestwindgod @cloak-of-ares @least-favorite-hades-kid @penelope-is-waiting @odysseus-of-ithaca-is-lost @aura-of-the-winds @lucifermorningstar-official @the-speedster-god @lethia-not-athena @the-god-ofwar @seleneandheliosog @mother-of-trust @/anyone )

(my master list)

(tell me if you want to be added or remove)

[literaryvein-reblogs]

Some Allergy Vocabulary

for your next poem/story

Allergic crease - A crease or pale line that develops across the lower part of the nose because of frequent upward wiping of the nose.

Angioedema - (or edema) Swelling

Dander - Material that is shed from the body of humans and animals that have fur, hair, or feathers.

Dust mite - A small mite invisible to the naked eye. Dust mites are widely distributed in homes and dust mite allergy is a major cause of asthma and allergic rhinitis (hay fever).

Elemental diet - A diet of predigested liquid containing amino acids, vitamins, minerals, electrolytes, and glucose.

Eosinophils - Cells that circulate in the blood. They attack tissues at the site of an allergic reaction causing damage.

Erythema - Reddening of the skin.

Macrophages - Scavengers whose job is to engulf or eat up infecting germs and even infected cells. Macrophages also help to overcome infection by secreting signals that help activate other cell types to fight against infections.

Monocytes - Cells that circulate in the blood and become macrophages in the tissues. These cells are very important in alerting the immune system about an infection.

Neutropenia - A condition that results when the body does not have enough neutrophils, an important white blood cell that fights infections. The lower your neutrophil count, the more vulnerable you are to infectious diseases.

Pollen count - (or a mold count) Is based on the measurement of the number of grains of pollen or mold spores in a cubic meter of the air. The higher the count, the greater the chance that people suffering from hay fever will experience symptoms when they are outdoors or exposed to outdoor air.

Pruritus - Itching

Urticaria - The medical word for hives, which are itchy, raised lumps that can vary in position from hour to hour or day to day.

Wheal - A raised whitish itchy lump, which occurs after skin prick test or after contact with an allergen and is a term also used to describe the individual lump seen in hives.

Wheeze - A whistling sound that can occur in the breathing tubes or airways. It is important to make your doctor aware of wheezing that reoccurs. Wheezing is often a symptom of asthma or COPD, but it may be related to temporary respiratory conditions such as pneumonia or bronchitis.

Sources: 1 2 3 ⚜ More: Word Lists

[wheelie-sick]

What is Idiopathic Mast Cell Activation Syndrome?

Idiopathic Mast cell activation syndrome (MCAS) is one of several mast cell disorders. MCAS occurs when there are a normal number of mast cells in a person's body but they over-release mast cell mediators causing random allergic reactions in multiple systems of the body. MCAS is incredibly common being present in an estimated 17% of the population.

Symptoms

MCAS symptoms are incredibly varied and always occur in multiple systems of the body. Anaphylaxis is common.

[ID: A graphic labeled "Some common symptoms of Mast Cell Disease" A graphic of a person standing in the center with multiple organs visible is shown. Around the person are lines pointing to specific areas of the body labeled with the body system and symptoms. Clockwise these read "Neurological headache, brain fog, cognitive dysfunction, anxiety, depression Cutaneous (Skin) flushing of the face/neck/chest, hives, skin rashes, itching with or without rash Cardiovascular light-heartedness, syncope (fainting), rapid heart rate, chest pain, low blood pressure, high blood pressure at the start of a reaction, blood pressure instability Gynecological uterine cramps, bleeding Urinary bladder irritability, frequent voiding Systemic and/or organ specific Anaphylaxis angioedema (swelling) Skeletal bone/muscle pain, osteopenia, osteoporosis Gastrointestinal diarrhea, nausea, vomiting, abdominal pain, bloating, gastroesophageal reflux disease (GERD) Ear/Nose/Throat/Respiratory nasal itching and congestion, throat itching and swelling, wheezing, shortness of breath and more" In the bottom left corner "Symptoms can be sudden and unpredictable in onset learn more at tmsforacure.org"]

MCAS symptoms are specifically not allergies. the reactions may look like allergies but the two are not the same and MCAS is not a condition meaning "many allergies" While MCAS can have some consistent triggers one of the defining features of the disease is that reactions are random and happen unpredictably.

Anaphylactic shock is not a requirement for diagnosis.

Diagnosis

MCAS is diagnosed by an immunologist. It is in part a diagnosis of exclusion and requires ruling out both allergies and systemic mastocytosis as well as other conditions such as certain types of tumors.

Diagnostic criteria for MCAS is debated. Some immunologists follow the symptom-based diagnosis approach in which case the diagnostic criteria are:

Recurring and severe anaphylactic-like episodes that involve more than one organ system

and

Positive response to mast cell stabilizing or mediator medications anaphylaxis-type symptoms

Others follow diagnostic criteria based on laboratory findings. In this case the diagnostic criteria are:

Episodic symptoms consistent with mast cell mediator release affecting two or more organ systems evidenced as follows:

Skin: urticaria, angioedema, flushing

Gastrointestinal: nausea, vomiting, diarrhea, abdominal cramping

Cardiovascular: hypotensive syncope or near syncope, tachycardia

Respiratory: wheezing

Naso-ocular: conjunctival injection, pruritus, nasal stuffiness

and

A decrease in the frequency or severity; or resolution of symptoms with anti-mediator therapy: H1 and H2 histamine receptor antagonists, anti-leukotriene medications (cysLT receptor blockers or 5-LO inhibitor), or mast cell stabilizers (cromolyn sodium)

and

Evidence of an elevation in a validated urinary or serum marker of mast cell activation: Documentation of elevation of the marker above the patient’s baseline during a symptomatic period on at least two occasions; or if baseline tryptase levels are persistently >15ng, documentation of elevation of the tryptase above baseline on one occasion. Total serum tryptase is recommended as the markers of choice; less specific (also from basophils) 24 hour urine histamine metabolites, or 11-beta-prostaglandin F2.

and

Primary (clonal) and secondary disorders of mast cell activation ruled out.

These are not all proposed diagnostic criteria as the subject is heavily debated. Generally, a laboratory-confirmed MCAS diagnosis is considered more legitimate.

Treatment

MCAS is a very treatable condition. Generally treatment follows a path from antihistamines -> mast cell mediators -> biologics.

Epipens are given to MCAS patients with a history of anaphylaxis.

Antihistamines are divided into 2 categories: H1 antagonists and H2 antagonists. These categories are determined based on the histamine receptor each one targets.

H1 antagonists mostly deal with systemic and cutaneous symptoms. H1 antagonists are also further divided into first and second generation antihistamines. first generation antihistamines include diphenhydramine (Benadryl) and Hydroxyzine. These tend to cause drowsiness. With second generation H1 antagonists cause fewer side effects and include drugs like loratadine (Claritin) and cetirizine (Zyrtec)

H2 antagonists primarily affect the gastrointestinal tract and include medications like famotidine (pepcid)

Typically when treating MCAS a person will be put on both a second generation H1 antagonist and an H2 antagonist.

When antihistamines do not treat symptoms well enough the next step is a mast cell mediator. The most common mast cell mediator is cromolyn sodium which is available by prescription only. (this is technically available OTC but it is at 1/50th the dose used for MCAS) Mast cell mediators work by preventing the degranulation of mast cells in the first place.

When both antihistamines and mast cell mediators are insufficient someone with MCAS might be prescribed a biologic such as Xolair to treat their remaining symptoms.

Sources:

American Academy of Allergy, Asthma, and Immunology

Mast Cell Hope

Mast Cell Activation Syndrome: Proposed Diagnostic Criteria

[does-truth-matter]

The CDC has quietly changed who should AVOID the MMR vaccine.

https://www.cdc.gov/vaccines/vpd/mmr/public/index.html

They now state that ANYONE that “Has a parent, brother or sister with a history of immune system problems” should AVOID THE MMR VACCINE!

What exactly is an 'immune system problem?" Every autoimmune disorder.

* Achalasia

* Addison’s disease

* Adult Still's disease

* Agammaglobulinemia

* Alopecia areata

* Amyloidosis

* Amyotrophic lateral sclerosis (Lou Gehrigs)

* Ankylosing spondylitis

* Anti-GBM/Anti-TBM nephritis

* Antiphospholipid syndrome

* Autoimmune angioedema

* Autoimmune dysautonomia

* Autoimmune encephalomyelitis

* Autoimmune hepatitis

* Autoimmune inner ear disease (AIED)

* Autoimmune myocarditis

* Autoimmune oophoritis

* Autoimmune orchitis

* Autoimmune pancreatitis

* Autoimmune retinopathy

* Autoimmune urticaria

* Axonal & neuronal neuropathy (AMAN)

* Baló disease

* Behcet’s disease

* Benign mucosal pemphigoid

* Bullous pemphigoid

* Castleman disease (CD)

* Celiac disease

* Chagas disease

* Chronic inflammatory demyelinating polyneuropathy (CIDP)

* Chronic recurrent multifocal osteomyelitis (CRMO)

* Churg-Strauss Syndrome (CSS) or Eosinophilic Granulomatosis (EGPA)

* Cicatricial pemphigoid

* Cogan’s syndrome

* Cold agglutinin disease

* Congenital heart block

* Coxsackie myocarditis

* CREST syndrome

* Crohn’s disease

* Dermatitis herpetiformis

* Dermatomyositis

* Devic’s disease (neuromyelitis optica)

* Discoid lupus

* Dressler’s syndrome

* Endometriosis

* Eosinophilic esophagitis (EoE)

* Eosinophilic fasciitis

* Erythema nodosum

* Essential mixed cryoglobulinemia

* Evans syndrome

* Fibromyalgia

* Fibrosing alveolitis

* Giant cell arteritis (temporal arteritis)

* Giant cell myocarditis

* Glomerulonephritis

* Goodpasture’s syndrome

* Granulomatosis with Polyangiitis

* Graves’ disease

* Guillain-Barre syndrome

* Hashimoto’s thyroiditis

* Hemolytic anemia

* Henoch-Schonlein purpura (HSP)

* Herpes gestationis or pemphigoid gestationis (PG)

* Hidradenitis Suppurativa (HS) (Acne Inversa)

* Hypogammalglobulinemia

* IgA Nephropathy

* IgG4-related sclerosing disease

* Immune thrombocytopenic purpura (ITP)

* Inclusion body myositis (IBM)

* Interstitial cystitis (IC)

* Juvenile arthritis

* Juvenile diabetes (Type 1 diabetes)

* Juvenile myositis (JM)

* Kawasaki disease

* Lambert-Eaton syndrome

* Leukocytoclastic vasculitis

* Lichen planus

* Lichen sclerosus

* Ligneous conjunctivitis

* Linear IgA disease (LAD)

* Lupus

* Lyme disease chronic

* Meniere’s disease

* Microscopic polyangiitis (MPA)

* Mixed connective tissue disease (MCTD)

* Mooren’s ulcer

* Mucha-Habermann disease

* Multifocal Motor Neuropathy (MMN) or MMNCB

* Multiple sclerosis

* Myasthenia gravis

* Myositis

* Narcolepsy

* Neonatal Lupus

* Neuromyelitis optica

* Neutropenia

* Ocular cicatricial pemphigoid

* Optic neuritis

* Palindromic rheumatism (PR)

* PANDAS

* Parkinson's disease

* Paraneoplastic cerebellar degeneration (PCD)

* Paroxysmal nocturnal hemoglobinuria (PNH)

* Parry Romberg syndrome

* Pars planitis (peripheral uveitis)

* Parsonage-Turner syndrome

* Pemphigus

* Peripheral neuropathy

* Perivenous encephalomyelitis

* Pernicious anemia (PA)

* POEMS syndrome

* Polyarteritis nodosa

* Polyglandular syndromes type I, II, III

* Polymyalgia rheumatica

* Polymyositis

* Postmyocardial infarction syndrome

* Postpericardiotomy syndrome

* Primary biliary cirrhosis

* Primary sclerosing cholangitis

* Progesterone dermatitis

* Psoriasis

* Psoriatic arthritis

* Pure red cell aplasia (PRCA)

* Pyoderma gangrenosum

* Raynaud’s phenomenon

* Reactive Arthritis

* Reflex sympathetic dystrophy

* Relapsing polychondritis

* Restless legs syndrome (RLS)

* Retroperitoneal fibrosis

* Rheumatic fever

* Rheumatoid arthritis

* Sarcoidosis

* Schmidt syndrome

* Scleritis

* Scleroderma

* Sjögren’s syndrome

* Sperm & testicular autoimmunity

* Stiff person syndrome (SPS)

* Subacute bacterial endocarditis (SBE)

* Susac’s syndrome

* Sympathetic ophthalmia (SO)

* Takayasu’s arteritis

* Temporal arteritis/Giant cell arteritis

* Thrombocytopenic purpura (TTP)

* Tolosa-Hunt syndrome (THS)

* Transverse myelitis

* Type 1 diabetes

* Ulcerative colitis (UC)

* Undifferentiated connective tissue disease (UCTD)

* Uveitis

* Vasculitis

* Vitiligo

* Vogt-Koyanagi-Harada Disease

Wonder how many doctors are paying attention?

~shared from Jodi Wilson

[atiny-for-life]

Regarding Wooyoung's Health

I thought it's best to make my own post to reach more people who may be concerned or confused about what Wooyoung is currently going through.

I'm glad KQ has always taken their health serious because there will be a lot of adjustments that'll have to be made to ensure Wooyoung's safety in the future so he can keep thriving as an artist and just as a person in general.

From what I've read up on, cholinergic uriticaria (which is the specific type he's dealing with according to the KQ announcement) is common but not yet fully understood (as is the case for most conditions). What you should know is that attacks can be caused by the following triggers:

Exercise (most common trigger)

High temperature exposure, eg, hot showers, saunas

Spicy food ingestion

Emotional stress (anger, anxiety, etc.)

I hope you can see why this would make it hard for someone who performs on stage for a living to be diagnosed.

To show you how absolutely serious this is, attacks can lead to the following:

Hives and skin irritation

Low blood pressure

Tightening of the respiratory muscles, leading to shortness of breath and wheezing

Angioedema, which is an abrupt, temporary, localised swelling of the deep dermal layer, subcutaneous tissue, and mucous membranes that can spread to the upper respiratory tract and intestines

Headaches

Abdominal cramps and diarrhoea

Asthma

Anaphylactoid and anaphylactic reactions

And more

But there are also good news: most affected see a strong improvement in their condition within just a few years of diagnosis and a full disappearance of symptoms after some time, which is fantastic and something I want everyone to keep in mind.

So please, send your love and support to Wooyoung, tell him to prioritize his health, that you want him to be safe and happy, but avoid phrases like "get better soon" because that's not how chronic conditions work and for the love of everything, don't tell him you're disappointed you won't get to see him or something along those lines - that comes across as cruel when you're in a situation completely outside your control. The last thing you should want is for him to feel guilty on top of everything else.

It's gotta be positivity only from here on out. If you care about him, you can send him pictures of your pets, tell him you love him and you're happy he's taking care of himself. The best medicine is laughter for a reason! Feeling good mentally makes your body stronger too so keep that in mind whenever you choose to leave a comment or send him a message.

From how we've heard Ateez talk about KQ, they'll make any adjustments necessary to ensure Wooyoung's safety and happiness so just be patient, wait for updates, and understand this is easiest for us and hardest for him so disregard your own feelings about the situation and keep in mind health comes above all else. Thank you!

Further reading:

Cleveland Clinic

DermNet

DocCheck Flexikon (German)

MedicalNewsToday

[greghatecrimes]

Season three is really banger after banger with the medical mysteries. they picked such interesting ones. hereditary angioedema, erythropoietic protoporphyria, cipa patient with a tapeworm, the fucking toothpick causing everything when they thought it was Wegener's, the person with dwarfism who didn't actually have dwarfism... Some of the most memorable medical cases of the whole show for sure