#Alzheimers treatment

[wikipediapictures]

Donepezil

[healthcare-insights]

Interesting FACTS about BRAIN

The brain is an incredible and essential organ that controls everything in our body. Though it makes up only about 2% of body weight, it uses 20% of the oxygen and energy we take in. For those experiencing brain-related issues, consulting a Neurologist in Hyderabad can be crucial.

Here are some fascinating facts about the human brain:

Short term memory can only store 7 pieces of information for 20 seconds

The average human brain weights 3 pounds and is made up of 73% water

Cholesterol is important for the brain to function

When intoxicated, the brain cannot form memories

When awake, the brain produces enough electricity to power a small light bulb

If you or a loved one is facing neurological concerns, reaching out to a Neurosurgeon in Malakpet or other experts can ensure proper care and treatment. The brain truly is a powerhouse!

[geezerwench]

Alzheimer’s Breakthrough: New Drug Shows Promise in Reversing Memory Loss and Cognitive Decline

[goldislops]

Nasal spray could ‘wash’ brain clean of Alzheimer’s disease proteins

Katherine Fidler

Amyloid plaques in Alzheimer's disease

Amyloid plaques are misfolded proteins aggregates beetween neurons, Alzheimer’s disease illustration (Credits: Getty Images/iStockphoto)

A nasal spray that helps ‘wash’ Alzheimer’s-causing proteins out of the brain could one day offer hope to millions who suffer from the disease.

Alzheimer’s is the most common form of dementia, affecting more than 940,000 people in the UK alone. As the world’s population ages, the number is increasing, expected to almost double every 20 years.

While the causes of the disease are still not fully understood, scientists have been studying the build-up of tau proteins in the brain that lead to cognitive decline. The proteins clump and form tangles, disrupting signals along neurons, or brain cells.

Now, a team from the University of Texas Medical Branch (UTMB) has found a potential way to get rid of the proteins.

The team developed a specific type of antibody, called TTCM2, which targets and clears tau plaques, or build-ups, restoring brain function.

To deliver the antibody straight to the brain, they hid it inside tiny particles that can be delivered by a nasal spray.

Illustration showing the nasal spray delivering antibodies directly to the brain

Nasal sprays can deliver drugs directly to the brain (Picture: UTMD)

Traditionally, drugs are delivered to the brain in the bloodstream, but this means they must be able to cross the tricky blood-brain barrier.

However, there is a more direct, non-invasive route, in which drugs can pass directly from the nasal mucosa – the sensitive lining of the nasal cavity – to the brain, known as intranasal administration.

The UTMB team tested this route on mice with tau build-ups similar to humans, and found it cleared the plaques after just one spray, resulting in significant cognitive improvements. In addition, it also resulted in higher levels of proteins that are beneficial for brain cell communication.

Alzheimer's and dementia research, conceptual image

Delivering drugs to the brain via the bloodstream doesn’t always work (Picture: Getty/Science Photo Libra)

Lead author Dr Rakez Kayed said: ‘This nasal spray approach opens new avenues for non-invasive delivery of tau therapeutic antibodies directly to the brain, and it holds promise for many neurodegenerative diseases.

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‘This method not only improves the delivery of therapeutic antibodies but also enhances their efficacy in clearing tau aggregates and improving cognitive functions.’

However, while the results are very exciting, the nasal spray antibody has so far only been tested in mice – more research is needed to determine if the treatment would be safe and effective in humans. The UTMB team plans to conduct further preclinical trials, with the aim of moving on to human testing.

First author Sagar Gaikwad said: ‘This advancement could significantly impact the treatment strategies for Alzheimer’s and related tauopathies, offering new hope for millions of patients suffering from these debilitating conditions.’

[halorvic]

[eretzyisrael]

By Diana Bletter

In a world first, researchers at the Hebrew University have discovered a distinct cellular pathway in the brain that indicates markers for future onset of Alzheimer’s disease, some 20 years before symptoms would be exhibited. This early detection could eventually lead to a treatment to prevent the degenerative disease.

“The study shows that Alzheimer’s disease is not just a form of accelerated aging but follows a different cellular path,” said Prof. Naomi Habib, and PhD students Anael Cain and Gilad Green of Hebrew University, who led the team of researchers at Columbia, Harvard University, and Rush Medical Center in Chicago.

Now that research has found the “molecular markers,” she said, “we can predict if an individual is on the cellular path to healthier aging, or a path to Alzheimer’s.”The video player is currently playing an ad.

This discovery will help lead toward appropriate treatments.

“We now believe we know what’s driving the disease, but we need to prove that changing the response would reverse that,” she said.

Using a data set from the prefrontal cortex of 437 aging brains, the researchers mapped 1.65 million brain cells and showed that these cellular changes — that start at least 20 years before the first signs of dementia — determine the fate of the aging brain and the progression of Alzheimer’s Disease.

The study was published last month in the peer-reviewed scientific journal Nature.

[theflashisgone]

Scientific fraud is the most baffling thing ever to me like do they think they're just going to make a huge breakthrough and no one will notice that it's fake by trying to replicate their results

[keenbotanist]

[aurahomeopathydr]

Alzheimer's homeopathy treatment in India

Aura Homeopathy provides specialized Alzheimer's homeopathy treatment in India, offering natural and holistic remedies to manage symptoms and slow cognitive decline. With a personalized approach, their treatments aim to enhance memory, improve focus, and support overall brain health, providing a safe and effective solution for Alzheimer's care.

[drrohitgupta]

Alzheimer’s disease is one of the most common forms of dementia, affecting millions of people globally. It progressively impairs memory, thinking skills, and eventually, the ability to carry out simple tasks. While the disease primarily impacts older adults, early diagnosis and treatment are crucial for managing symptoms and slowing its progression. This is where the expertise of a neurologist comes into play.

A neurologist is a medical specialist trained to diagnose and treat conditions related to the brain and nervous system. When it comes to Alzheimer’s disease, their role is pivotal in managing memory loss, providing early diagnosis, and offering treatment plans that can improve a patient’s quality of life.

[medacess]

Can Alzheimer's be cured with Stem Cell Therapy in India?

While stem cell therapy offers promising results for Alzheimer's disease, However, in India, advanced stem cell treatments have shown potential in slowing disease progression, improving memory, and enhancing quality of life for patients.

[neurocareplus]

Dementia - Alzheimer's disease Treatments in Katy, TX

Dr. Nicolas Nammour offers specialized dementia and Alzheimer’s disease treatments focusing on personalized care and improving cognitive health in Katy, TX.

[feelinghtrtms]

Access the Best Treatment for Early Alzheimer’s and OCD in Toronto 

Looking for effective Treatment for early Alzheimer’s in Toronto or treatment for obsessive compulsive disorder in Toronto? At Feellightrtms, we offer advanced rTMS therapy, a non-invasive method that stimulates specific areas of the brain to alleviate symptoms. Our treatments are tailored to each patient, ensuring a personalized approach to mental health care. Whether you're dealing with cognitive decline from early Alzheimer's or seeking relief from OCD, our expert team is here to help you on the path to recovery. Visit us today to learn more about our innovative treatments.

[dynamichealthinsights]

Decoding the Alzheimer's Puzzle: The Critical Role of Genetic Research

Alzheimer’s disease, often described as a thief that steals memories and identities, is a complex and devastating neurodegenerative disorder affecting millions worldwide. Its impact extends far beyond the individual, casting a long shadow over families and communities. In the relentless pursuit of understanding and combating this formidable foe, scientists have turned to the fascinating world of…

[bestneurologistinindore]

Best Dementia Treatment in Indore, Best Doctor Alzheimer’s Disease Treatment in Indore | Dr Indu Bhana

Maitry Neuro Care Clinic, the most advanced, trusted and reliable clinic in the field of neurology. They have a complete solution for brain problems, migraine, epilepsy, sciatic, dementia treatment in Indore. Call to book and appointment: +91-7725921197, +91-9301895907