#Achiko

[nofatclips]

Rhythm by Envy (featuring Achico) from the album The Fallen Crimson

[achikomizuya]

I've created my Sonic Team Chaotix OC & Leader of the "Team Indigo" along with Mighty the Armadillo and Ray the Flying Squrriel, Achit the Octogirl! She's a dark, relaxed, soft, and kind-hearted female octopus humanoid that becomes the Leader of "Team Indigo" alongside her two friends, Mighty the Armadillo and Ray the Flying Squrriel

(Fun Fact: English fanmade name "Achit" means "Dark", and Japanese fanmade name "Achiko" means "Child of Darkness".)

[toastedbutterbrick]

Please draw my Sonic OC, Achiko Mizuya the Octogirl (Aka. Acht (Ah-chit) Dedf1sh the Octogirl and yes, she's 4th member of the Team Chaotix of Vector the Crocodile, Espio the Chameleon, & Charmy Bee <3)

I LOVE HERRR <3333

[suth-sardian]

A little late, but happy birthday, Ajisiro Achiko!

[inland-shivers]

Please draw my Sonic OC, Achiko Mizuya (Aka. Acht (Ah-chit) the Octogirl, and yes, she's 4th member of the Team Chaotix of Vector the Crocodile, Espio the Chameleon, & Charmy Bee <3)

The most human-looking cephalopod I've ever drawn.

[latestmarketresearchnews]

Aptamers Industry 2030 Size, Share, Business Growth, Demand and Applications

The global aptamers market was valued at USD 1.94 billion in 2022 and is projected to grow at a significant compound annual growth rate (CAGR) of 24.54% from 2023 to 2030. Aptamers have garnered attention due to recent advancements in their generation, purification, and ability to effectively target and kill specific cells, which make them a powerful tool in therapeutic development.

The COVID-19 pandemic has presented unique challenges in the field of treatment due to the virus's high mutation rate. Currently, there are no fully effective treatments specifically targeting COVID-19 across all its variants. However, aptamers, particularly nucleic acid-based and peptide aptamers, have shown promise as a potential approach to combat COVID-19. The heightened focus on biotechnological solutions for COVID-19 treatment has spurred government and private sector initiatives to accelerate R&D in this area.

One example of government support is a contract awarded in September 2020 by the Department of Community & Economic Development, which allocated USD 320,000 to Aptagen LLC to support the research and development of a novel COVID-19 treatment using aptamers. This financial support aims to foster innovation in developing therapeutic solutions using aptamer technology.

Gather more insights about the market drivers, restrains and growth of the Aptamers Market

Regional Insights:

North America Aptamers Market Trends

North America led the global aptamers market with a 44.48% share in 2022. This dominance can be attributed to several factors:

High Prevalence of Chronic Diseases: Rising rates of chronic illnesses such as cancer, cardiovascular diseases, and neurological disorders have fueled the demand for targeted therapies, boosting interest in aptamer-based treatments.

Robust Healthcare Infrastructure: North America's well-developed healthcare system supports advanced research in biotechnology and pharmaceuticals, facilitating the growth of the aptamers market.

Increased Interest in Aptamer R&D: Research laboratories and institutions in the U.S. and Canada are increasingly focusing on aptamer research to explore novel treatments and diagnostic tools.

An example of North America’s commitment to aptamer R&D is seen in Noxxon Pharma's announcement in April 2022. The company presented the results of its NOX-A12 GLORIA trial for treating brain cancer at the American Society of Clinical Oncology annual meeting, underscoring the region's significant advancements in aptamer-based therapies.

Asia Pacific Aptamers Market Trends

The Asia Pacific region is expected to witness the fastest growth in the aptamers market, with a CAGR of 26.18% during the forecast period. This rapid growth is driven by factors such as:

Approval of New Aptamer-Based Products: Regulatory approvals of aptamer-based products are accelerating market expansion. For instance, Achiko AG entered an agreement in April 2020 with the Pengurus Wilayah Nahdlatul Ulama DKI, a prominent Islamic association in Indonesia, to promote its COVID-19 diagnostic kit AptameX.

Increased Healthcare Demand: As healthcare needs grow, Asia Pacific countries, particularly China, Japan, and India, are adopting advanced technologies and investing in biotechnology.

The collaboration between Achiko AG and Pengurus Wilayah Nahdlatul Ulama DKI in Indonesia highlights the potential for aptamer-based products in diagnostic applications. This organization, which has around 90 million members, offers a significant market for innovative diagnostic tools, particularly as they address the ongoing COVID-19 pandemic.

Browse through Grand View Research's Category Biotechnology Industry Research Reports.

The global plasma fractionation market size was estimated at USD 35.8 billion in 2024 and is projected to grow at a CAGR of 8.5% from 2025 to 2030.

The global sickle cell anemia testing and screening market size was estimated at USD 425.7 million in 2024 and is projected to grow at a CAGR of 12.1% from 2025 to 2030.

Key Companies & Market Share Insights:

Leading companies in the aptamers market are actively pursuing strategies to enhance their product offerings and expand their market presence. These strategies include:

Product Modification: Companies are refining their existing aptamer products to improve efficacy and applicability across various therapeutic areas.

New Product Approvals: Firms are seeking regulatory approvals for novel aptamer-based products to strengthen their market share.

Mergers and Acquisitions: Strategic mergers and acquisitions are helping companies expand their product portfolios and enter new regional markets.

For instance, in January 2023, Aptamer Group announced a collaboration with BaseCure Therapeutics to develop Optimer-targeted therapies. Optimer technology is designed to enhance aptamer-targeted therapeutics, allowing for more precise drug delivery to target cells. This collaboration demonstrates the potential for aptamers in therapeutic applications and reflects the ongoing trend of partnerships within the industry aimed at driving innovation and broadening the use of aptamers in medical treatments.

Key Aptamers Companies:

SomaLogic

Aptamer Group

Aptadel Therapeutics

Base Pair Biotechnologies

Noxxon Pharma

Vivonics Inc.

Aptagen, LLC

TriLink Biotechnologies

Altermune LLC

AM Biotechnologies

Order a free sample PDF of the Aptamers Market Intelligence Study, published by Grand View Research.

[researchreportinsight]

Aptamers Market Analysis by Application 2030

The global aptamers market was valued at USD 1.94 billion in 2022 and is projected to grow at a significant compound annual growth rate (CAGR) of 24.54% from 2023 to 2030. Aptamers have garnered attention due to recent advancements in their generation, purification, and ability to effectively target and kill specific cells, which make them a powerful tool in therapeutic development.

The COVID-19 pandemic has presented unique challenges in the field of treatment due to the virus's high mutation rate. Currently, there are no fully effective treatments specifically targeting COVID-19 across all its variants. However, aptamers, particularly nucleic acid-based and peptide aptamers, have shown promise as a potential approach to combat COVID-19. The heightened focus on biotechnological solutions for COVID-19 treatment has spurred government and private sector initiatives to accelerate R&D in this area.

One example of government support is a contract awarded in September 2020 by the Department of Community & Economic Development, which allocated USD 320,000 to Aptagen LLC to support the research and development of a novel COVID-19 treatment using aptamers. This financial support aims to foster innovation in developing therapeutic solutions using aptamer technology.

Gather more insights about the market drivers, restrains and growth of the Aptamers Market

Regional Insights:

North America Aptamers Market Trends

North America led the global aptamers market with a 44.48% share in 2022. This dominance can be attributed to several factors:

High Prevalence of Chronic Diseases: Rising rates of chronic illnesses such as cancer, cardiovascular diseases, and neurological disorders have fueled the demand for targeted therapies, boosting interest in aptamer-based treatments.

Robust Healthcare Infrastructure: North America's well-developed healthcare system supports advanced research in biotechnology and pharmaceuticals, facilitating the growth of the aptamers market.

Increased Interest in Aptamer R&D: Research laboratories and institutions in the U.S. and Canada are increasingly focusing on aptamer research to explore novel treatments and diagnostic tools.

An example of North America’s commitment to aptamer R&D is seen in Noxxon Pharma's announcement in April 2022. The company presented the results of its NOX-A12 GLORIA trial for treating brain cancer at the American Society of Clinical Oncology annual meeting, underscoring the region's significant advancements in aptamer-based therapies.

Asia Pacific Aptamers Market Trends

The Asia Pacific region is expected to witness the fastest growth in the aptamers market, with a CAGR of 26.18% during the forecast period. This rapid growth is driven by factors such as:

Approval of New Aptamer-Based Products: Regulatory approvals of aptamer-based products are accelerating market expansion. For instance, Achiko AG entered an agreement in April 2020 with the Pengurus Wilayah Nahdlatul Ulama DKI, a prominent Islamic association in Indonesia, to promote its COVID-19 diagnostic kit AptameX.

Increased Healthcare Demand: As healthcare needs grow, Asia Pacific countries, particularly China, Japan, and India, are adopting advanced technologies and investing in biotechnology.

The collaboration between Achiko AG and Pengurus Wilayah Nahdlatul Ulama DKI in Indonesia highlights the potential for aptamer-based products in diagnostic applications. This organization, which has around 90 million members, offers a significant market for innovative diagnostic tools, particularly as they address the ongoing COVID-19 pandemic.

Browse through Grand View Research's Category Biotechnology Industry Research Reports.

The global plasma fractionation market size was estimated at USD 35.8 billion in 2024 and is projected to grow at a CAGR of 8.5% from 2025 to 2030.

The global sickle cell anemia testing and screening market size was estimated at USD 425.7 million in 2024 and is projected to grow at a CAGR of 12.1% from 2025 to 2030.

Key Companies & Market Share Insights:

Leading companies in the aptamers market are actively pursuing strategies to enhance their product offerings and expand their market presence. These strategies include:

Product Modification: Companies are refining their existing aptamer products to improve efficacy and applicability across various therapeutic areas.

New Product Approvals: Firms are seeking regulatory approvals for novel aptamer-based products to strengthen their market share.

Mergers and Acquisitions: Strategic mergers and acquisitions are helping companies expand their product portfolios and enter new regional markets.

For instance, in January 2023, Aptamer Group announced a collaboration with BaseCure Therapeutics to develop Optimer-targeted therapies. Optimer technology is designed to enhance aptamer-targeted therapeutics, allowing for more precise drug delivery to target cells. This collaboration demonstrates the potential for aptamers in therapeutic applications and reflects the ongoing trend of partnerships within the industry aimed at driving innovation and broadening the use of aptamers in medical treatments.

Key Aptamers Companies:

SomaLogic

Aptamer Group

Aptadel Therapeutics

Base Pair Biotechnologies

Noxxon Pharma

Vivonics Inc.

Aptagen, LLC

TriLink Biotechnologies

Altermune LLC

AM Biotechnologies

Order a free sample PDF of the Aptamers Market Intelligence Study, published by Grand View Research.

[tamanna31]

Aptamers Market Share, Supply, Sales, Manufacturers, Competitor and Consumption 2023 to 2030

Aptamers Industry Overview

The global aptamers market size was valued at USD 1.94 billion in 2022 and is expected to grow at a compounded annual growth rate (CAGR) of 24.54% from 2023 to 2030.

Recent advancements in the generation, purification, and drug delivery for killing target cells have attracted the attention of many researchers towards aptamers due to the competitive advantages associated with them. Some of the advantages include small molecular size, low immunogenicity, low cost of manufacturing, and lesser side effects compared to antibodies; may fuel the R&D of novel aptamers, thereby driving market growth. Despite significant efforts, there are currently no highly effective treatments available against COVID-19 infections due to a large number of genetic mutations. However, biotechnological approaches appear to be promising in the treatment of COVID-19.

Gather more insights about the market drivers, restrains and growth of the Aptamers Market

Consequently, nucleic-acid based aptamers & peptide aptamers might be effective against treating COVID-19 infection. Thus, various initiatives are being undertaken by the government to boost the R&D of novel treatment for COVID-19. For instance, in September 2020, the Department of Community & Economic Development awarded a contract of USD 320,000 to Aptagen LLC for the research and development of novel treatment for the COVID-19.

The aptamers based diagnostic kits and assays developed by using SELEX technology have the ability to develop high-affinity neutralizers and bioprobes for monitoring SARS-COV-2 & COVID-19 biomarkers. Therefore, the introduction of diagnostic kits in the market for disease diagnosis is projected to drive market growth. For instance, in December 2021, Achiko AG received approval from the Ministry of Health of the Republic of Indonesia for Aptamex, a COVID-19 diagnostic kit. Aptamex is a second-generation diagnostic kit developed by using DNA aptamer-based technology that is a cost-effective, chemically synthesized, and an emerging diagnostic kit for healthcare.

Aptamers based diagnostic products are the preferred choice among diagnostic and pathology labs for the diagnosis of disease at the cellular level due to their small size, high specificity, selectivity, and efficacy. Thus, increasing prevalence of diseases such as cancer, CVD, and AMD may increase the footfall of patients in labs for the diagnosis of these diseases, consequently, increasing demand for aptamer based diagnostic products. According to Cancer Research UK estimates, around 27.5 million people are expected to be diagnosed with cancer by 2040.

In March 2022, SomaLogic announced the initiation of assaying samples using SomaScan Assay for the European Prospective Investigation into Cancer and Nutrition (EPIC) study by analyzing 210 million protein measurements from 30,000 samples. This will help researchers in predicting cancer by better understanding its nature, which in turn may contribute in market growth by addressing the increased demand.

As of now, Macugen developed by Eyetech Pharmaceuticals, Inc., (currently commercialized by Bausch Health Companies Inc.) is only the U.S. FDA approved (2004) therapeutic aptamer available in the market. It is used for the treatment of age-related muscular degeneration disorder (AMD). Technological advancements in research encourage scientists’ attention towards the development of novel aptamer based therapeutic drugs for the treatment of various diseases. Currently, there are a number of products under different clinical trials including Zimura developed by IVERIC Bio, Inc., for the treatment of patients with drug AMD. Thus, expected approval of this drug may boost the growth of the market over the period.

Browse through Grand View Research's Biotechnology Industry Research Reports.

• The global structural biology & molecular modeling techniques market size was valued at USD 7.13 billion in 2023 and is projected to grow at a CAGR of 15.4% from 2024 to 2030.

• The global targeted DNA RNA sequencing market size was valued at USD 10.12 billion in 2023 and is projected to grow at a CAGR of 19.4% from 2024 to 2030.

Global Aptamers Market Report Segmentation

This report forecasts revenue growth and provides an analysis of the market trends in each of the sub-markets from 2018 to 2030. For the purpose of this study, Grand View Research has segmented the aptamers market on the basis of type, application, and region.

Type Outlook (Revenue, USD Million; 2018 - 2030)

Nucleic Acid Aptamer

Peptide Aptamer

Application Outlook (Revenue, USD Million; 2018 - 2030)

Diagnostics

Therapeutics

Research & Development

Others

Regional Outlook (Revenue, USD Million; 2018 - 2030)

North America

US

Canada

Europe

Germany

UK

France

Italy

Spain

Denmark

Sweden

Norway

Asia Pacific

Japan

China

India

Australia

Thailand

South Korea

Latin America

Brazil

Mexico

Argentina

MEA

South Africa

Saudi Arabia

UAE

Kuwait

Key Companies & Market Share Insights

Major players are adopting strategies such as modification in the existing product, approval of new products, and mergers & acquisitions for product enhancements and regional expansion to attain a greater market share. For instance, in January 2023, Aptamer Group collaborated with BaseCure Therapeutics for the development of Optimer-targeted therapies. Such initiatives can open new avenues of growth for applications of aptamers in therapeutics. Some of the prominent players in the global aptamers market include:

SomaLogic

Aptamer Group

Aptadel Therapeutics

Base Pair Biotechnologies

Noxxon Pharma

Vivonics Inc.

Aptagen, LLC

TriLink Biotechnologies

Altermune LLC

AM Biotechnologies

Order a free sample PDF of the Aptamers Market Intelligence Study, published by Grand View Research.

[hellogrinbearfilms]

REPORTERS WITHOUT BORDERS / The First Speech (DC) from Giordano Maestrelli on Vimeo.

Production Company - Stink Films, Berlin Director - Giordano Maestrelli Director of Photography - Konrad Losch Managing Director - Justin Stiebel Executive Producer - Moritz Merkel Executive Producer - Florian Hülbig Producer - Melody Micmacher Creative Assistant - Bruno Beserra Editor - Simon Klinkertz Colorist - Joseph Bicknell @ Company 3 Color Producer - Cassidy Conway Music & Sound Design - Satelite Audio Music Direction - Hurso Ambrifi Client Service - Fernanda Costa Post Production & Mixing - Carla Cornea, Andre Giannini, Vithor Moraes, Arthur Dossa Production Coordinator: Camila Guedes, Leticia Oliveira, Bea Vieira Sound Studio  - Studio Funk Berlin Executive Producer - Uta Wittchen & Katharina Knieling Sound Engineer / Audio & Music - Marius Wiechmann Storyboard Artist - Eilis Scally

Reporters Without Borders Germany (RSF): Head of Communications - Sylvie Ahrens-Urbanek Public Relations Officer - Prisca Martaguet

INNOCEAN Berlin: CCO - Gabriel Mattar ECD - Ricardo Wolff Head of Art - Maso Correa Heck Associate Design Director - Will Cega Art Director - Leon Celay Copywriter - Juan Andrés Kebork Motion Designers - Carlos Suárez and Alexander Aleksidze Head of Capacity Management - Paulina Gonzalez Producer / Head of Production - Fabian Barz Post Production Producer - Jan Scholz Strategy Director - Jörn Ballentin Sr. Strategist - Odile Breffa Senior Media Manager - Maja Lah

Service Production Georgia - Metro Productions Executive Producer - Aleksandre Gabilaia Head of Production - Maia Gurabanidze Head of Bidding - Mariam Tevdorashvili 1st AD - Sopio Parjiani 2nd AD - Mariami Gugushvili Production Manager - Tato Pantsulaia Production Coordinator - Nino Megrelishvili Unit Manager - Merab Rostomashvili Location manager - Natia Chomakhidze Location manager assistant - Zaza Chigladze Transportation Manager - Davit Peradze Transportation Manager - David Maghlakelidze PA / Chaperone - Mariam Tsiklauri PA - Irakli Kakabadze

Set Manager - Konstantine Chkhaidze Set helpers - Buba Kupatazde Set helpers - Lasha Kupatadze Set helpers - Saba Sagrishvili Cleaner - Svetlana Bagdasarian

Art Director - Sopo Bazghadze Set Dresser - Shota Bagalishvili Production Designer Assistant - Achiko Shamakhia Art Assistant - Nina Jandieri Art Assistant: MURAL - Giorgi Khavelashvili Art Assistant: MURAL - Erekle Gordeladze

Stylist - Ketevan Kalandadze Stylist Assistant - Nino Chkoidze MUA - Veriko Bedeladze HAIR - Nino Dashniani

Focus Puller - Irakli Jgenti Camera AC - Guram Mosikashvili Camera AC - Khatia Khalvashi Playback Assistant - Koba Rostiashvili DIT - Gosha Tabidze Gaffer - Shalva Leluashvili Key Grip - Tengo Kasradze Grip / Light - Mikheil Gvalia Grip / Light - Giorgi Gogbaidze Grip / Light - Davit Eremadze Grip / Light - Gia Guluashvili Grip / Light - Davit Gogichaishvili Grip / Light - Vako Leluashvili Grip / Light - Giorgi Eremadze Dolly Crew - Giorgi Zakaidze Dolly Crew - Lasha Gugushvili Dolly Crew - Teimuraz Kupradze

Driver - Gia Tetrazde Driver - Avto Ugulava Driver - Gigo Lomtatidze Driver - Zaza Magaldadze Driver - David Odishelidze Driver - Roland Gogokhia Driver - Giorgi Koshadze Driver - Anatoli Kliushnichenko Driver - Ramaz Davitiani Driver - Giorgi Gogashvili

Service Production Brazil - Stink Saõ Paulo / Yatta Films Executive Producer - Rafa Rocha Production Manager - Maria Eduarda Caldeira Brino Production Manager - Daniel Lombardi Production Assistant - Sofia Lombardi Production Assistant - Victoria Valenti Chaperone - Nahaiana Vieira Cardoso 1st AD - Jan Monczka 2nd AD - Juliana Dias Caldas

Set Manager - Marcelo de Menezes Cachapuz Set Manager Assist - Marcelo Pasin Set Manager Assist - Jones silva de Oliveira Set Manager Assist - Adriano Pereira

Location Manager - Bruno De Souza Palaoro Location Manager Assist - Marcelo Araujo Frangipani

Production Designer - Martino Piccinini Art Assistant - Alice Goulart Furtado Art Producer - Soraia De Matia Props Coordinator - Camila Vettorazi Franzen Set Decorator - Julia Perez Paiva Melgarejo Props Master - Andre Luiz Micael Valli Castilho Props master Assist - Rafael Serpa Gerchmann Props master Assist - Victoria Perez Paiva Melgarejo Props master Assist - Lucas Rodrigues Do Amaral Props master Assist - Joabel Fontoura De Azevedo [Biel] Props master Assist - Maria Vitória Reimundo Varante Props master Assist - João Vitor Copetti Teixeira Helper - Maurício Ignácio Silveira Helper - Alisson Barboza Maciel

Costume Designer - Isadora Bertolucci Costume Assist - Samara Raquel Pereira Da Silva Costumer - Adriana Talaveira [Mana] HMU - Luana Ramos Zinn HMU - Gabrielle Ávila de Oliveira HMU - Eduarda Lombardi Pellenz Brum [Dudinha]

1st AC - Marcelo Ostrovski Bevilacqua 2nd AC - Gabriela Bortolon De Oliveira Video Assist - Laurie Braatz DIT - Juliano Rodrigues Moreira

Gaffer - Roberto Ramos Best Boy - Flavio Pinheiro De Souza [Cabeça] Electrician - Frederico Barbosa Ramos Electrician - Jefferson dos Santos Oliveira Helper - Vinícius Rojas Lopes Helper - Filipe Rodrigues Alves

Key Grip - Andre Luis Da Cunha Campanhol Best Boy Grip - Fabio Da Silva Dias Grip - Rodrigo Lopes Espíndola Grip - Ismael Borges Santos Helper - Josué Da Costa Celaro Helper - Nicolas Gabriel Luciano Huf

Casting Producer - Amanda Michelini Schmitz Casting Assistant - Pedro Alberto Santana Sanhudo [Pepa]

[g-dvalle]

REPORTERS WITHOUT BORDERS / The First Speech (DC) from Giordano Maestrelli on Vimeo.

Production Company - Stink Films, Berlin Director - Giordano Maestrelli Director of Photography - Konrad Losch Managing Director - Justin Stiebel Executive Producer - Moritz Merkel Executive Producer - Florian Hülbig Producer - Melody Micmacher Creative Assistant - Bruno Beserra Editor - Simon Klinkertz Colorist - Joseph Bicknell @ Company 3 Color Producer - Cassidy Conway Music & Sound Design - Satelite Audio Music Direction - Hurso Ambrifi Client Service - Fernanda Costa Post Production & Mixing - Carla Cornea, Andre Giannini, Vithor Moraes, Arthur Dossa Production Coordinator: Camila Guedes, Leticia Oliveira, Bea Vieira Sound Studio  - Studio Funk Berlin Executive Producer - Uta Wittchen & Katharina Knieling Sound Engineer / Audio & Music - Marius Wiechmann Storyboard Artist - Eilis Scally

Reporters Without Borders Germany (RSF): Head of Communications - Sylvie Ahrens-Urbanek Public Relations Officer - Prisca Martaguet

INNOCEAN Berlin: CCO - Gabriel Mattar ECD - Ricardo Wolff Head of Art - Maso Correa Heck Associate Design Director - Will Cega Art Director - Leon Celay Copywriter - Juan Andrés Kebork Motion Designers - Carlos Suárez and Alexander Aleksidze Head of Capacity Management - Paulina Gonzalez Producer / Head of Production - Fabian Barz Post Production Producer - Jan Scholz Strategy Director - Jörn Ballentin Sr. Strategist - Odile Breffa Senior Media Manager - Maja Lah

Service Production Georgia - Metro Productions Executive Producer - Aleksandre Gabilaia Head of Production - Maia Gurabanidze Head of Bidding - Mariam Tevdorashvili 1st AD - Sopio Parjiani 2nd AD - Mariami Gugushvili Production Manager - Tato Pantsulaia Production Coordinator - Nino Megrelishvili Unit Manager - Merab Rostomashvili Location manager - Natia Chomakhidze Location manager assistant - Zaza Chigladze Transportation Manager - Davit Peradze Transportation Manager - David Maghlakelidze PA / Chaperone - Mariam Tsiklauri PA - Irakli Kakabadze

Set Manager - Konstantine Chkhaidze Set helpers - Buba Kupatazde Set helpers - Lasha Kupatadze Set helpers - Saba Sagrishvili Cleaner - Svetlana Bagdasarian

Art Director - Sopo Bazghadze Set Dresser - Shota Bagalishvili Production Designer Assistant - Achiko Shamakhia Art Assistant - Nina Jandieri Art Assistant: MURAL - Giorgi Khavelashvili Art Assistant: MURAL - Erekle Gordeladze

Stylist - Ketevan Kalandadze Stylist Assistant - Nino Chkoidze MUA - Veriko Bedeladze HAIR - Nino Dashniani

Focus Puller - Irakli Jgenti Camera AC - Guram Mosikashvili Camera AC - Khatia Khalvashi Playback Assistant - Koba Rostiashvili DIT - Gosha Tabidze Gaffer - Shalva Leluashvili Key Grip - Tengo Kasradze Grip / Light - Mikheil Gvalia Grip / Light - Giorgi Gogbaidze Grip / Light - Davit Eremadze Grip / Light - Gia Guluashvili Grip / Light - Davit Gogichaishvili Grip / Light - Vako Leluashvili Grip / Light - Giorgi Eremadze Dolly Crew - Giorgi Zakaidze Dolly Crew - Lasha Gugushvili Dolly Crew - Teimuraz Kupradze

Driver - Gia Tetrazde Driver - Avto Ugulava Driver - Gigo Lomtatidze Driver - Zaza Magaldadze Driver - David Odishelidze Driver - Roland Gogokhia Driver - Giorgi Koshadze Driver - Anatoli Kliushnichenko Driver - Ramaz Davitiani Driver - Giorgi Gogashvili

Service Production Brazil - Stink Saõ Paulo / Yatta Films Executive Producer - Rafa Rocha Production Manager - Maria Eduarda Caldeira Brino Production Manager - Daniel Lombardi Production Assistant - Sofia Lombardi Production Assistant - Victoria Valenti Chaperone - Nahaiana Vieira Cardoso 1st AD - Jan Monczka 2nd AD - Juliana Dias Caldas

Set Manager - Marcelo de Menezes Cachapuz Set Manager Assist - Marcelo Pasin Set Manager Assist - Jones silva de Oliveira Set Manager Assist - Adriano Pereira

Location Manager - Bruno De Souza Palaoro Location Manager Assist - Marcelo Araujo Frangipani

Production Designer - Martino Piccinini Art Assistant - Alice Goulart Furtado Art Producer - Soraia De Matia Props Coordinator - Camila Vettorazi Franzen Set Decorator - Julia Perez Paiva Melgarejo Props Master - Andre Luiz Micael Valli Castilho Props master Assist - Rafael Serpa Gerchmann Props master Assist - Victoria Perez Paiva Melgarejo Props master Assist - Lucas Rodrigues Do Amaral Props master Assist - Joabel Fontoura De Azevedo [Biel] Props master Assist - Maria Vitória Reimundo Varante Props master Assist - João Vitor Copetti Teixeira Helper - Maurício Ignácio Silveira Helper - Alisson Barboza Maciel

Costume Designer - Isadora Bertolucci Costume Assist - Samara Raquel Pereira Da Silva Costumer - Adriana Talaveira [Mana] HMU - Luana Ramos Zinn HMU - Gabrielle Ávila de Oliveira HMU - Eduarda Lombardi Pellenz Brum [Dudinha]

1st AC - Marcelo Ostrovski Bevilacqua 2nd AC - Gabriela Bortolon De Oliveira Video Assist - Laurie Braatz DIT - Juliano Rodrigues Moreira

Gaffer - Roberto Ramos Best Boy - Flavio Pinheiro De Souza [Cabeça] Electrician - Frederico Barbosa Ramos Electrician - Jefferson dos Santos Oliveira Helper - Vinícius Rojas Lopes Helper - Filipe Rodrigues Alves

Key Grip - Andre Luis Da Cunha Campanhol Best Boy Grip - Fabio Da Silva Dias Grip - Rodrigo Lopes Espíndola Grip - Ismael Borges Santos Helper - Josué Da Costa Celaro Helper - Nicolas Gabriel Luciano Huf

Casting Producer - Amanda Michelini Schmitz Casting Assistant - Pedro Alberto Santana Sanhudo [Pepa]

[fygmo]

REPORTERS WITHOUT BORDERS / The First Speech (DC) from Giordano Maestrelli on Vimeo.

Production Company - Stink Films, Berlin Director - Giordano Maestrelli Director of Photography - Konrad Losch Managing Director - Justin Stiebel Executive Producer - Moritz Merkel Executive Producer - Florian Hülbig Producer - Melody Micmacher Creative Assistant - Bruno Beserra Editor - Simon Klinkertz Colorist - Joseph Bicknell @ Company 3 Color Producer - Cassidy Conway Music & Sound Design - Satelite Audio Music Direction - Hurso Ambrifi Client Service - Fernanda Costa Post Production & Mixing - Carla Cornea, Andre Giannini, Vithor Moraes, Arthur Dossa Production Coordinator: Camila Guedes, Leticia Oliveira, Bea Vieira Sound Studio  - Studio Funk Berlin Executive Producer - Uta Wittchen & Katharina Knieling Sound Engineer / Audio & Music - Marius Wiechmann Storyboard Artist - Eilis Scally

Reporters Without Borders Germany (RSF): Head of Communications - Sylvie Ahrens-Urbanek Public Relations Officer - Prisca Martaguet

INNOCEAN Berlin: CCO - Gabriel Mattar ECD - Ricardo Wolff Head of Art - Maso Correa Heck Associate Design Director - Will Cega Art Director - Leon Celay Copywriter - Juan Andrés Kebork Motion Designers - Carlos Suárez and Alexander Aleksidze Head of Capacity Management - Paulina Gonzalez Producer / Head of Production - Fabian Barz Post Production Producer - Jan Scholz Strategy Director - Jörn Ballentin Sr. Strategist - Odile Breffa Senior Media Manager - Maja Lah

Service Production Georgia - Metro Productions Executive Producer - Aleksandre Gabilaia Head of Production - Maia Gurabanidze Head of Bidding - Mariam Tevdorashvili 1st AD - Sopio Parjiani 2nd AD - Mariami Gugushvili Production Manager - Tato Pantsulaia Production Coordinator - Nino Megrelishvili Unit Manager - Merab Rostomashvili Location manager - Natia Chomakhidze Location manager assistant - Zaza Chigladze Transportation Manager - Davit Peradze Transportation Manager - David Maghlakelidze PA / Chaperone - Mariam Tsiklauri PA - Irakli Kakabadze

Set Manager - Konstantine Chkhaidze Set helpers - Buba Kupatazde Set helpers - Lasha Kupatadze Set helpers - Saba Sagrishvili Cleaner - Svetlana Bagdasarian

Art Director - Sopo Bazghadze Set Dresser - Shota Bagalishvili Production Designer Assistant - Achiko Shamakhia Art Assistant - Nina Jandieri Art Assistant: MURAL - Giorgi Khavelashvili Art Assistant: MURAL - Erekle Gordeladze

Stylist - Ketevan Kalandadze Stylist Assistant - Nino Chkoidze MUA - Veriko Bedeladze HAIR - Nino Dashniani

Focus Puller - Irakli Jgenti Camera AC - Guram Mosikashvili Camera AC - Khatia Khalvashi Playback Assistant - Koba Rostiashvili DIT - Gosha Tabidze Gaffer - Shalva Leluashvili Key Grip - Tengo Kasradze Grip / Light - Mikheil Gvalia Grip / Light - Giorgi Gogbaidze Grip / Light - Davit Eremadze Grip / Light - Gia Guluashvili Grip / Light - Davit Gogichaishvili Grip / Light - Vako Leluashvili Grip / Light - Giorgi Eremadze Dolly Crew - Giorgi Zakaidze Dolly Crew - Lasha Gugushvili Dolly Crew - Teimuraz Kupradze

Driver - Gia Tetrazde Driver - Avto Ugulava Driver - Gigo Lomtatidze Driver - Zaza Magaldadze Driver - David Odishelidze Driver - Roland Gogokhia Driver - Giorgi Koshadze Driver - Anatoli Kliushnichenko Driver - Ramaz Davitiani Driver - Giorgi Gogashvili

Service Production Brazil - Stink Saõ Paulo / Yatta Films Executive Producer - Rafa Rocha Production Manager - Maria Eduarda Caldeira Brino Production Manager - Daniel Lombardi Production Assistant - Sofia Lombardi Production Assistant - Victoria Valenti Chaperone - Nahaiana Vieira Cardoso 1st AD - Jan Monczka 2nd AD - Juliana Dias Caldas

Set Manager - Marcelo de Menezes Cachapuz Set Manager Assist - Marcelo Pasin Set Manager Assist - Jones silva de Oliveira Set Manager Assist - Adriano Pereira

Location Manager - Bruno De Souza Palaoro Location Manager Assist - Marcelo Araujo Frangipani

Production Designer - Martino Piccinini Art Assistant - Alice Goulart Furtado Art Producer - Soraia De Matia Props Coordinator - Camila Vettorazi Franzen Set Decorator - Julia Perez Paiva Melgarejo Props Master - Andre Luiz Micael Valli Castilho Props master Assist - Rafael Serpa Gerchmann Props master Assist - Victoria Perez Paiva Melgarejo Props master Assist - Lucas Rodrigues Do Amaral Props master Assist - Joabel Fontoura De Azevedo [Biel] Props master Assist - Maria Vitória Reimundo Varante Props master Assist - João Vitor Copetti Teixeira Helper - Maurício Ignácio Silveira Helper - Alisson Barboza Maciel

Costume Designer - Isadora Bertolucci Costume Assist - Samara Raquel Pereira Da Silva Costumer - Adriana Talaveira [Mana] HMU - Luana Ramos Zinn HMU - Gabrielle Ávila de Oliveira HMU - Eduarda Lombardi Pellenz Brum [Dudinha]

1st AC - Marcelo Ostrovski Bevilacqua 2nd AC - Gabriela Bortolon De Oliveira Video Assist - Laurie Braatz DIT - Juliano Rodrigues Moreira

Gaffer - Roberto Ramos Best Boy - Flavio Pinheiro De Souza [Cabeça] Electrician - Frederico Barbosa Ramos Electrician - Jefferson dos Santos Oliveira Helper - Vinícius Rojas Lopes Helper - Filipe Rodrigues Alves

Key Grip - Andre Luis Da Cunha Campanhol Best Boy Grip - Fabio Da Silva Dias Grip - Rodrigo Lopes Espíndola Grip - Ismael Borges Santos Helper - Josué Da Costa Celaro Helper - Nicolas Gabriel Luciano Huf

Casting Producer - Amanda Michelini Schmitz Casting Assistant - Pedro Alberto Santana Sanhudo [Pepa]

[achikomizuya]

Achit the Octogirl but See-Through Shades

[bonnie-the-mutt]

here's my playlist !

here's a shorter playlist that's a bit more upbeat :)

you could also try the Steven universe or Disney soundtrack/instrumentals ! ( the Rapunzel soundtrack is super underrated )

also, music by achiko aoba and the Howls moving castle soundtrack is very soothing for bedtime.

Help me make a playlist! What are some of your favorite songs to listen to that are child friendly? Bonus points if it's from a show/video game or is an instrumental song (⁠◡⁠ ⁠ω⁠ ⁠◡⁠)

[correctsuccess]

How SOSV-backed Achiko pivoted from financial services to health tech during the COVID-19 pandemic – TechCrunch Many firms needed to adapt throughout the COVID-19 pandemic. For SOSV-backed Achiko, this meant shifting its focus from cell fee providers to inexpensive COVID-19 screening. Achiko’s platform combines an app referred to as Teman Sehat (“Well being Buddy” in Indonesian) for funds and preserving take a look at data, and proprietary low-cost testing kits utilizing DNA aptamers, or artificial str... #Achiko #correct_success #Covid19 #Credit_Cards #credit_score #Finance #financial #Financial_health #Health #pandemic #pivoted #services #SOSVbacked #tech #TechCrunch

[latestmarketresearchnews]

Aptamers Market - Structure, Size, Trends, Analysis and Outlook 2030

The global aptamers market was valued at USD 1.94 billion in 2022 and is projected to grow at a compound annual growth rate (CAGR) of 24.54% from 2023 to 2030. This rapid growth is being driven by significant advancements in the development, purification, and drug delivery systems for targeting and eliminating harmful cells, which have garnered the attention of researchers. Aptamers possess several competitive advantages over traditional antibodies, including smaller molecular size, lower immunogenicity (reduced immune response), reduced manufacturing costs, and fewer side effects. These benefits are encouraging research and development (R&D) efforts in the creation of new aptamers, fueling market expansion.

Despite considerable research, no highly effective treatments for COVID-19 have been identified, partly due to the virus's extensive genetic mutations. However, biotechnological approaches, including the use of aptamers, hold promise in combating COVID-19 infections. Nucleic acid-based aptamers and peptide aptamers are believed to offer potential therapeutic solutions for the virus, and various government initiatives are supporting the development of novel treatments for COVID-19. For example, in September 2020, the Department of Community & Economic Development awarded USD 320,000 to Aptagen LLC to fund research and development of a novel COVID-19 treatment. This investment reflects the growing recognition of aptamers' potential in addressing unmet medical needs.

Gather more insights about the market drivers, restrains and growth of the Aptamers Market

Aptamers are also proving valuable in diagnostics. Using SELEX (Systematic Evolution of Ligands by Exponential Enrichment) technology, aptamer-based diagnostic kits and assays can develop high-affinity neutralizers and bioprobes for detecting SARS-CoV-2 and other COVID-19 biomarkers. These innovations are expected to further drive market growth. For example, in December 2021, Achiko AG received approval from the Indonesian Ministry of Health for its COVID-19 diagnostic kit, Aptamex. Aptamex is a second-generation, cost-effective diagnostic tool based on DNA aptamer technology, representing an emerging solution in healthcare diagnostics.

Type Segmentation Insights:

The aptamers market is segmented into nucleic acid aptamers and peptide aptamers. In 2022, the nucleic acid aptamers segment dominated the market, holding a 78.19% share, and is expected to exhibit the highest growth during the forecast period. Many companies are actively exploring the therapeutic mechanisms of nucleic acid aptamers for treating various disorders, such as age-related macular degeneration (AMD). For instance, in June 2021, the U.S. Food and Drug Administration (FDA) granted IVERIC BIO (formerly Ophthotech Corporation) a written agreement under the Special Protocol Assessment (SPA) for the design of its phase 3 clinical trial, GATHER2. The trial aims to assess the efficacy of Zimura, a nucleic acid aptamer-based drug, for patients with geographic atrophy (GA) secondary to AMD. This FDA approval is expected to significantly bolster the growth of the nucleic acid aptamer segment.

The peptide aptamer segment is anticipated to experience substantial growth, with a projected CAGR of 22.77% from 2023 to 2030, driven by its broad applications in diagnostics and therapeutics. For instance, in August 2021, scientists from the Engineering Center for Microtechnology and Diagnostics developed an innovative biosensor for multiparametric express testing in the preclinical diagnostics of cardiovascular diseases. This testing uses next-generation biochips, which are based on a peptide aptamer marker system and molecular recognition technology. The researchers designed peptide aptamers using data from the Data Bank and Protein 3D software. The introduction of such advanced products in the market is likely to increase the utilization of peptide aptamers, contributing to the segment's growth.

In summary, the aptamers market is poised for rapid expansion due to the advantages of aptamers in therapeutic and diagnostic applications, advancements in technology, and ongoing R&D efforts. The market's growth is further supported by government initiatives, regulatory approvals, and the increasing use of aptamer-based solutions in areas such as COVID-19 treatment, diagnostics, and the management of other medical conditions.

Order a free sample PDF of the Aptamers Market Intelligence Study, published by Grand View Research.