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somecunttookmyurl · 4 years

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I'm very curious about the research you mentioned concerning CYP2D6 metabolism. Could you post or DM the name of the study? Is your plan to inhibit CYP2D6 by taking CBD or an anti-histamine to increase the effectiveness of the anphetamine based ADHD meds you're taking? Seems like an interesting (and well researched) plan - I hope it works for you if that's what you're doing!

YOU ACTIVATED MY TRAP CARD. I’m gonna put this under a readmore so as to not bore the other 3,066 of you with weirdly specific pharmacology and pharmacogenetics talk Disclaimer: I am not a doctor, or a pharmacist, or any sort of medical professional at all. I have absolutely zero qualifications in pharmacology I’m just a nerd with half a psychology degree, a talent for study design, and shitty fucking doctors.

So I first learned about CYP26D metabolism (and the broader P450 cytochrome) in like 2017 from a friend doing a PhD in things much smarter than me. I’ve always been a Feral Drug Goblin (resistant if not immune to a lot of drugs) and she seemed to think that’s what was happening. Which tracks because like. 90% of the stuff that doesn’t work on me is a CYP2D6 substrate (the rest are CYP3A4 so I might have more than one defect, but if there’s something funky going on on 3A4 the effect is less pronounced)

Later discovered I have hypermobile Ehlers-Danlos Syndrome (hEDS) and like... many if not most EDS sufferers have *at least* one P450 defect . Around 80% or so of people with chronic pain more generally have at least one P450 defect. It’s not something I’ve been tested for because a) even though CYP2D6 metabolism and its effect on drug treatment has been studied for like 30 years, the NHS only started introducing genomic testing for it in 2019 and b) getting a referral would require finding a doctor who knows what it is which, like, lmao. Honestly though we can be about 99% certain I’m an ultrarapid metaboliser, all things considered. Mostly I want a genomic test to see if any of the others are broken.

Now, I don’t know why it took me four years to think of it but over the weekend at 2:30am (I’m not allowed to have a thought during daylight hours actually) that like... logically speaking... if you gave a potent CYP2D6 inhibitor to an ultrarapid metaboliser it would normalise (or at least improve, depending on how many functional copies of the gene I’m dealing with like people have been found with thirteen copies) the metabolic function. Absolute galaxy brain moment.

Of course combining a CYP2D6 substrate and a CYP2D6 inhibitor generally carries a “moderately severe” interaction warning because if you’re alrealy, like, normal that could be dangerous. So I had a dig around to see if anybody had studied that specific thing and whether it was actually safe.

It took me... a pretty long time because this concept is massively understudied. I mean there’s 1001 studies on “does being an ultrarapid metaboliser of CYP2D6 affect [x substrate drug]” to the extent it’s like... yeah dude. The answer is yes. It’s always yes. I think we’ve proved this concept. Don’t think you need to do it for every single drug. We get it. There are a couple though. Both of the studies were only 5 participants, and were done 20 years ago (2000 and 2001) but in both cases all participants showed... honestly pretty amazingly positive responses and no ill effects. Which is why I’m so baffled that seemingly nobody has studied it since. Like “well, this went fantastically well! We shall never speak of it again” The first study gave the participants debrisoquine hydroxylation, which is the substance they use to test the function of CYP2D6 when they do the genomic test. So they weren’t on a CYP2D6 substrate already they were given it specifically for the study. Then they were given quinidine (an anti-arrhythmic which has sadly been disconintues) as an inhibitor. Without quinidine, the metabolic ratio of debrisoquine in the participants after 6 hours was 0.01 - 0.07. Which is, like, fuck all. With quinidine that amount was 12.6, 10.1, 9.2, 2.4, and 2.2. Participants had 3, 3, 4, 13, and 13 copies of the gene respectively so the more copies you have the less improvement you see, but < 0.1 to 2.2 is still huge https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2014903/ The second study in 2001, also 5 participants, administered nortriptyline as the substrate and then used paroxetine (an SSRI) as the inhibitor. After taking nortriptyline for a week, all participants had very low subtherapeutic levels of the drug in their systems. Following 2 weeks of treatment with paroxetine, 4/5 participants had normally-expected therapeutic levels of noritryptiline. The other participant withdrew after 1 week of paroxetine treatment after getting side effects from it but still had an increase in noritryptiline levels in that time so it was working he just didn’t tolerate paroxetine very well. https://sci-hub.se/https://ascpt.onlinelibrary.wiley.com/doi/abs/10.1016/S0009-9236(01)78384-1

Those are, to my knowledge, the only studies done specifically to test whether you can normalise liver function using an inhibitor. There is a case study from 2006 of a 6 year old boy with ADHD who didn’t respond to drugs and was confirmed to be an ultrarapid metaboliser. The authors recommend usage of an inhibitor in such cases

https://sci-hub.se/https://journals.lww.com/psychopharmacology/Citation/2006/08000/An_ADHD_6_year_old_Child_Ultrarapid_Metabolizer.25.aspx

I can’t have paroxetine or fluoxetine because I have a bipolar-spectrum disorder and historically me and SSRIs are not friends. However buproprion (wellbutrin) is an inhibitor which I was prescribed before to counteract a side effect from atomoxetine and like I was definitely more functional at the time? But that was way before I had this genius plan, or knew it was an inhibitor, so. There’s been a supply issue here for it since July. So yeah. I’m going to be taking CBD. Amphetamines do absolutely fuck all by themselves so like literally my plan is “taking weed pills to try and make my liver talk to meth properly” which sounds absolutely ridiculous. Gonna be hilarious if it fuckin’ works. I’m going to be doing a proper study and writing it all up and everything. Emailed the researchers involved in the 3 studies to see if they’re interested in my data like 20 years later lmao but if you wanna read the study outline it’s here: https://docs.google.com/document/d/1TOnToHMH7UhYMFM9qtv-4ZWmaV7Pr6IQeYv6QDAGVrQ/edit?usp=sharing Just gonna keep going unti it either works, or the amount of CBD required becomes too expensive (which would be like 9 weeks max bc I can’t afford to be taking more than 60mg CBD every day forever).

#thepropervillain #bet you regret asking now huh

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rediscoveringmichelle · 3 years

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An Apple a day keeps the cravings away

January 2021, back in London after spending Christmas at home in Ireland with my family. This time had been a very different experience to the last. Freer, both mentally and physically. The last time I had been home was at the beginning of the global pandemic, restricted to the 2km radius of my home in Clontarf, North Dublin. However, on this occasion not only had restrictions been lifted by the Taoiseach for the Christmas period, I had lifted my own restrictions too. The beginning of the pandemic was the turning point of my recovery and now, 9 months later, I was no longer limiting myself to 3 healthy meals per day, with no snacks and a strict schedule of two 10km runs per week and a minimum 2 and half hours of walking per day. I felt happier and healthier than I had been in years, able to relax and enjoy late night glasses of wine and mince pies with my parents, meals out with friends and the odd day of rest and relaxation with nothing but a few hours of TV to pass the day. It didn’t matter how much weight I had put on; I had gained my life and laugh back, and I would be forever grateful for the lesson I had learnt thanks to this awful pandemic. That making myself thinner and fitter, didn’t make me any happier. And that being physically healthy is nothing if you destroy your mental and social health too.

January 2018 was really where it all began. Recently single and having spent a lot of my newfound freedom on nights out, eating takeaways and drinking large volumes of alcohol, I had understandably put on a bit of weight. The guy I had been seeing, suddenly stopped texting me and I felt rejected. My parents were back to living their lives after their run-ins with poor health. Dad back to smothering his toast in thick layers of butter and Mum loving her newfound ‘real-Mum’ life of Pilates and coffee catch ups since selling her practice for good. I was no longer needed. Mum didn’t need me to drive her to chemo or cook my Dad his no red meat, no oil, no salt dinners. I felt anxious as they went back to living their lives. No longer able to control them, especially my dad. I couldn’t force him into living a by-the-book healthy lifestyle. But I figured what I could control was myself. I could be the healthiest person I could possibly be. And with the added benefit of making that guy wish he’d never let me go. My perfectionist self would ensure that I would be the perfect picture of health. No cheating, no dieting, just a new lifestyle. A new me. One I could love.

I scoured the internet for all the advice on changing your lifestyle, getting fit and losing weight. Running apparently boosted your metabolism and was an efficient way to burn calories and fat. So, I started by running 5km, three times a week. Weights would help then to reduce my body fat and tone up so I coupled the running with strength training in the gym, also three times a week. I pounded out Kelsey Wells workout routines, while listening to ‘This is me’ from The Greatest Showman, a song about not being afraid to show the world exactly who you are, as I was ironically punishing my body into a shape that was not naturally me. I strictly followed Dad’s cardiologist’s advice and cooked everything from scratch, substituting beef mince for turkey mince and not using oil, butter or salt in my cooking. I cut out all snacks and limited myself to three meals per day. Social Media became my home ground for weight loss advice. ‘You’re not hungry, you’re thirsty. Drink some water.’ ‘No pain, no gain.’ ‘Ignore your cravings and they will eventually go away.’ ‘Craving sugar? Have an apple instead’. Each day would end with eating an apple to stave off the cravings and to quieten the rumbles in my stomach.

I started weighing my food, tracking everything from litres of water drunk and then steps walked and active minutes of exercise. I upped my runs gradually to 10km, twice a week because social media told me that after running for 35 minutes, you no longer just burn calories, but also fat. And yes, I do realise that anyone who has a degree in anything science related would quickly realise these were all completely made up and not based on fact, but I guess I wanted to believe them. I would believe anything that forced me to push (or punish) myself more. I stopped going out for drinks or dinner with friends. Too many calories and too worried that I wouldn’t be able to get up and run in the morning, unable to flex from the specific days I went running, for fear I would never run again. When I moved to London, I spent my weekends walking 40 thousand steps so that I could then earn a slice of banana bread from Deliciously Ella’s Vegan & Gluten Free Deli. I felt a rush of joy wash over me each time I saw the number on the scales or the minutes of my 10km runs decline, but like a drug, the high didn’t last long. I was addicted. I had no trust in myself. ‘You’re so controlled’, they complimented me. But deep down, I felt like there was a lazy, sugar and fat loving girl inside me. An imposter in a gradually reducing body. Fearing that just one biscuit and I would be back as that unhappy and overweight rejected girl.

I really believed that being thinner and looking like those girls I idolised on Instagram would make me happier. They were all smiling, surely that meant they were happy? As the compliments turned to concern, I felt that surely people were just jealous of how much weight I had managed to lose. Weight loss was something to be proud of, wasn’t it? The truth of it all didn’t hit me until the pandemic. As I sat up in my bed struggling to breathe on the night of the Taoiseach’s first lockdown announcement, I started to wonder what I was really fearing. During a time when people were dying, all I could fear was not being able to exercise enough and being locked up in a house full of food. I feared putting on weight and relinquishing control. I felt trapped with nothing to look forward to. Holidays cancelled and my boyfriend of two months at home with his family 167km away in Belfast. That was my rock bottom.

In an effort to cheer myself up I started to make a list of all the things I wanted to do post lockdown. Have date nights in with my boyfriend, making pizzas, ordering takeaways and eating breakfast in bed. Then the excitement of getting to do these things started to dwindle as the anxiety crept in, as I tried to count up how much exercise I would need to do in order to earn those nights. A day in bed with no exercise? Nope, that’s a no go. And that’s when it hit me. I had made myself thin, with the thought that then I would be lovable and that then I could enjoy my life. But I was thinner, thinner than I’d been since I was a preteen and I still wouldn’t let myself go enough to do the things I deeply wanted to do. To let myself enjoy life. How freeing it would be to just, let go!

My love for learning kicked in and I made the decision to start reading up and educating myself. I came across a book my mum had not so subtly left lying around the house. ‘Just Eat it – How Intuitive eating can help you get your shit together around food’ by Laura Thomas. I didn’t believe I had an eating disorder until I started reading her book. As she listed off the disorders, she then came to Orthorexia – defined as an unhealthy obsession with healthy eating or over exercising. ‘When was the last time you even asked yourself what you’d like instead of what you ‘can’ or ‘should’ eat?’ she queried. The sad reality was that I couldn’t remember. ‘We trust our phones more than we trust our bodies’. Well that was certainly true for me. She used science, showing that weight was in fact not a determinant of health but that by exercising, eating healthy and not smoking we could be healthy, regardless of our size. That eating a donut didn’t in fact negate the nutrients of the carrot we ate earlier. And that white flour was actually infused with calcium and that those carbs are what give us energy to move and enjoy life. My eyes gradually opened to all the lies diet culture had taught me and I felt empowered.

I moved on to more books and podcasts and started culling my social media feed of anyone that didn’t make me feel good. I started following intuitive eating dietitians and anti-diet advocates. Following people of all shapes and sizes and realising how biased our society is towards people in smaller bodies. Not just the size of airplane seats but assuming that all health issues experienced by fat people can be solved by weight loss. I learnt that the night sweats I had been experiencing, the pretty much non-existent sex drive and the inability to maintain body heat for any length of time were in fact all side effects of the restricted eating and over-exercising. Half the time I didn’t even look as thin as I had become because I was wearing so many layers of clothes in order to keep warm. Walking around the house with a hot water bottle strapped to my waist and wearing a fur coat indoors while out for dinner with friends. Only now can I laugh at the image of it. I started to make a list of all the things I would gain through gaining weight and glancing back over it now, I have gained all of these and more. My headspace, my laughter, my body heat and a fantastic relationship that I thankfully didn’t destroy because of my restrictive, anxious mind-set.

My recovery hasn’t been easy. The steps toward eating intuitively start with banishing your food rules and allowing yourself to eat what you want. A process that takes time before you can start tuning into your hunger and fullness cues again and introducing gentle nutrition. It involved allowing myself to devour entire tubs of Oatly chocolate fudge ice-cream, multiple evenings per week. Making my way through all the delicious Deliveroo takeaway options London had to offer – Honest Burgers red meat beef burgers with rosemary salted fries, Franco Manca pizzas, with all the toppings, and Kin & Deum Thai curries, with full fat coconut milk. Gradually I started being able to listen to my body and trust it. Whether it hungered for a salmon stir-fry or was seeking out a slice of chocolate cake. The interesting thing being, that months later it now craves nutritious food the majority of the time. And that by allowing it to have higher sugar or fat containing foods whenever it wants, I no longer feel out of control around them. I no longer find myself devouring three large sized bags of crisps in one sitting, overtaken by the fear that I will never let myself eat them again.

I have days where I find myself critiquing my larger thighs in the mirror but instead of allowing the thoughts consume me, I allow them float by with curiosity and continue about my day knowing that the way I look doesn’t define me and that the greatest things about me have nothing to do with my body shape or size. I am a thoughtful friend, who prides herself at remembering important moments in friends’ lives. A courageous girl who isn’t afraid to try new things, whether that be travelling solo across Vietnam or signing up to a surf and yoga retreat in Cornwall. A creative person who loves to draw and a lifelong learner that is open to new ideas and wants to challenge her way of thinking. My body will change a lot over the next 50 plus years of my life, but the great thing is that thanks to freeing myself from the disease, I get to look forward to the possibility of being alive for that long and to enjoying every waking moment, no longer postponing life for when I look or am a certain way.

#recovery #healing #dietculture #orthorexia #bodyimage #eatingdisorder #rediscoveringlife

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donotexterminateupgradepudding · 4 years

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Lucifer Morningstar is an introvert. A very awkward and unusual introvert.

In an attempt to not create a bunch of random side-blogs, I’m just going to drop this here. Sorry Doctor Who/Torchwood fans.

With the whole covid-19 thing, I’ve been trapped at home more than I had anticipated recently and I was looking for something a bit more fun and frivolous to watch so I finally gave Lucifer a go.

I honestly don’t know why it took me so long to get to this, my brother had watched it when it was on tv and had mentioned it in passing several times. Suffice to say, once I finally gave into Netflix, I found it to be quite an enjoyable watch.

What really struck me in the serious is how it becomes obvious that Lucifer is an introverted character who is hurt. Wait - what you are thinking? He’s an introvert? Oh man, he’s totally a huge introvert.

Let me walk you through why he’s clearly an introvert despite a quick glance at his outward actions.

1.) Hiding in plain sight.

An interesting aspect to his personality is how he hides in plain sight. When he moves to LA, he rents the building that houses Lux and his penthouse suite. Lux is a place where he is surrounded by people, if he wants to partake in revelry all he needs to do is go downstairs and party with people in the club. However, he can also retreat to his place easily which is surprisingly well stocked with books and another piano for him to play in private. I doubt all of his books are for show, he frequently denies thinking deeply about things, but he always seems to be one step ahead of others which has always implied to me he plays the “I’m smarter than I look/act” card. Early on in the show, he occasionally invited people up to his place to party but it wasn’t a common experience. Think of the pizza delivery guy being invited to stay and party.

Despite his love of drinking, drug use and sex, he makes it quite clear that drinking and drug use rarely have an effect on him for long. He is rarely hung over or wasted since his metabolism clears the alcohol too quickly for him to feel it and on multiple occasions he states he mainly drinks as he likes the taste. One of the few times he was high was after he smoked a massive amount of pot at the teenage delinquent recovery farm as indicated by him sitting at the detective’s desk eating potato chips and dipping them in nutella realizing it was an amazing flavor combination. For him, drugs seem to simply be something that is fun and a way to amuse himself and based on his drinking, it is mainly a way to meet and socialize with people.

As far as the sex, it is clear that he uses his casual hook-ups as a fun distraction. To avoid any possible intimacy with others, he hides behind the fact that sex is a pleasurable act and by keeping his sex life 100% casual, no person in his or her right mind would even consider dating him. He has made himself impossible to be seen as possible long term boyfriend in a steady relationship. He likely struggles with his own angelic power to pull out people’s desires and his ability to seduce them. Since his default is to have people literally throw themselves at him, he likely sees most of them acting in response to his powers and necessarily to him as a person. As he wants people to follow their desires and free-will (as he simply removed the inhibitions that were present and did not create them) he gladly indulges them as well as himself. If I were him, I’d be like “well why not?” an attractive person wants to sleep with me, sure do it, no harm, no foul.

I found it most telling based on how sensitive he is to his sexual reputation as well as his ability to meet his current sexual partner’s needs. First off, when a random kid pretended to be him, he was incredibly upset that his imposter lacked his skills. He’s Lucifer Morningstar, he has skills and a reputation associated with them. Secondly, when the detective decided to interview his previous partners for the past 8 weeks (all 92 of them) two things were very obvious i.) he went to great lengths to make sure no matter what he did, that person had the most amazing sex of his or her life ii.) not a single person he slept with saw it as anything more than an amazing night of no strings attracted sex. His actions did not inspire them to want more of a relationship from him. How his facial expression become quite sad as all 92 of them stated it was just empty sex showed how alone he is. Another unusual trait is that he has been the most sexually responsible angel ever. Granted, the vast majority of angels were never going to have sex in the first place, yet he has a much more responsible track record than Amenadiel. It is clear that he has had sex with thousands upon thousands of humans over the years and he never once resulted in a human-angel pregnancy. This may also be linked to the fact that Amenadiel by default, desires a ‘normal’ regular relationship while Lucifer has been avoiding having a “normal” relationship. It would imply that if he found someone to have a kid with, he would be in a “normal” long term relationship with that person.

Overall, his first career on earth was to make sure he had an establishment that represented what he felt others perceived as his core personality, that as the devil, he would have to surround himself by partying and temptations. Owning Lux is a way for him to keep up appearances and maintain his public persona as well as his persona that is seen by celestial beings. Lucifer is a classic example of a character who is totally alone in a crowd.

2.) Few close friends

Another true introvert trait is to have a small tight knit group of friends. Lucifer fits to this exactly. He has excellent social skills, and again due to his former job and his nature, yet does many actions by smooth, polite and calculated actions - from a distance. His job of granting favors is based on how he knows someone, who knows someone, forming a vast network he has to draw upon to make sure that the favors work out the way the person would like them to. He doesn’t do the favors though because he cares for the person, more than he seems to do it to pass the time until he finds a job with more meaning.

It is starting his second job as a civilian consultant for the LAPD that his preference and need for a small friend group becomes obvious. The most obvious one is his relationship with Chloe.

Chloe Decker: He is first intrigued at why his powers do not work on her, his immediate physical attraction to her as well as seeing her as a kindred spirit also drew him to her. She is the outcast of the department and he knows all too well what it feels like to be the literal outcast. As a result of their common situation and the fact he can’t sway her, the two of them can speak openly and honestly. Granted, the biggest issue with his relationship with Chloe is the fact that she denies the obvious truth that he tells her even though she has seen enough evidence that he likely is not some random British guy living in LA running a high end nightclub.

As their relationship deepens he begins to find comfort in the fact that despite his inability to influence her, she still appreciates his company and values him as a friend and a work partner. Even though he panics and holds her miracle status against her at first, he comes to realize she can’t be held responsible for something she has no control of and is unaware of. Linda time and time again tries to get him to realize that he keeps her away due to his absolute fear that she would reject him. Since she’s the only person who could accept him as is, it means her acceptance of him is the biggest risk to his own heart in regards to her.

In part, his complicated relationship is tied to his fear that she would reject him, so him loving and caring for a single person as he does for her is too risky. He’s a seriously hurt dude, he’s terrified of being hurt anymore by someone he cares for. Chloe really takes a long time to realize how deeply he is hurt. I get that she’s his opposite but I do felt out of all of the characters, she got short end of the stick in regards to character development. Everyone else has had major changes and realizations yet she only sort of struggled with Lucifer’s identity in the first half of season 4 and she was off her “mark” when she was a bit preachy with him. Thankfully, she stopped that bit and realized that he more needed her to listen to him and to support him. It really got that concept that sometimes you need to just be there for someone and not try to fix it - since Chloe is a fixer.

Mazikeen: She is his right-hand woman. The only demon to leave hell to follow him to earth, she first acted as his personal assistant, running the day to day operations of Lux and also working as a bartender. Despite all of their conflicts, they care deeply for each other and have each other’s back.

The hardest part of growth in their relationship is when it went from master-servant/boss-assistant to more that of peers. Even as he began to change in how he worked with humans, he keep their relationship as their default from hell. He really hurt her feelings since she developed feelings and both of them are terrible at expressing them to others. They have a relationship and work dynamic that they had for thousands and thousands of years - it is pretty impressive that they are learning and growing in a relatively short time period to respect each other and mature.

I found the most emotionally moving parts between them to be in season 3 when Chloe begins to get involved with Cain/Pierce and he expresses his worry that at least he has her and she’ll never leave him. Maze interprets this as him being selfish and treating her as his number 2. She lashes out at him and all he does is look back at her in return is hurt as he almost quivers. Since she was his right hand woman in hell, she is the person with whom he has had the longest and most trusting relationship with since being cast into hell. Did he phrase things in a way that helped in the situation - no. But was he telling her his honest feelings that he really does feel like she is someone who is always there for him and supports him - yes. When she goes behind his back to work with Cain/Pierce, he’s hurt and feels betrayed. Sure, some of it is karmic payback for the times he’s hurt her, but after his failed experiment with Abel, he has every right to not just pop willy-nilly between earth and hell.

I have the vibe that they will eventually settle into a sibling like relationship treating each other the same way he interacts with his angel siblings like Amenadiel and Azrael.

Ella Lopez: So far Ella has been the only human friend that he has worked with with whom he hasn’t used his angelic charms on. He was uncomfortable around her at first; she’s religious, she’s outwardly friendly and very much into giving hugs. Ella “wastes” her time on what he would see as pointless pleasantries in the office. Yes, Lucifer will lay on the pleasantries, but his always have a purpose - Ella’s are just her being nice. He did like her opinion that the devil got a bad rap, but then she kept thinking he was a method actor in addition to being a nightclub owner.

Despite their obvious differences the two of them are both very straightforward people who have a strong sense of personal justice and are dedicated to solving the crimes. He quickly begins to joke around with her and with her four older brothers, she finds no issue with dealing with his antics - it is more like par for the course.

The fact that Azrael also couldn’t help but become friends with her seems to indicate she has some sort of personality that celestial beings really like, especially those who have the shittier jobs e.g. Lucifer running hell and punishing and Azrael being the angel of death dealing with, well, death. The fact that she made sure Ella would become friends with Lucifer was really sweet and even though he was at first upset since he doesn’t like people trying to manipulate with him, he realized that Azrael’s action was in right place. She got her favorite brother and favorite human to become friends since she knew they would get along even if she couldn’t be with them - you know, having the whole angel of death as her day job.

His love of Ella as a friend though came out when her older brother Jay was in town and mixed up in the illegal diamond cleaning. Yes, he brought his own feelings with his older brother into the mix, but he was correct. Jay is not the absolutely perfect brother, he was involved in shady stuff. I think when he confronted Jay was one of the best scenes in regards to him standing up for and protecting his friends. He made it very clear that if Jay ever hurt Ella again he’d be in trouble as he knew how important it was to her to continue to see her brother in her own most positive light.

I really get the vibe that they feed off of each other being goofballs - Ella was a nerd and picked on as kid and had a lot of issues to deal with. He’s the cast out son, they are both outcasts on the rebound and they like to have fun with each other. This really comes to a head in season 4 when Lucifer, Chloe and Ella go to the nudist colony. Chloe is a complete stick in the mud and by the time she turns around the two of them are naked and ready to go. As adults on their own and away from their family and their former “teenage” issues they finally get to be who they want to be and I just think their dynamic duo antics are adorable. She is the friend that will do silly things with him while Chloe remains too, well stoic. When Ella has her crisis of faith, Lucifer doesn’t fan the flames instead, he’s confused how to react so he doesn’t tell her what to think.

Trixie: She immediately loved Lucifer from the moment she met him. He is incredibly awkward with her. He’s not sure to do with her little kid hugs, he tries to not hold her hand when they investigate the elite private school. Yet, no matter how frequently he calls her a little urchin and doesn’t understand why she likes him, she grows on him.

I personally loved her bedroom sign in the first season - “Trixie’s room - no boys allowed - except for Lucifer.”

Trixie is a classic example of kid radar seeing people for who they are; she accepts Lucifer and Maze with no judgement, she just sees them as these rad adults whom she can play with.

I really liked when he tried to buy her the new doll since she destroyed her old one - in a way he respected her kid logic - did it teach her a lesson - no. But it was a logical extension as a means to an end. He came from a background of illogical parenting so to speak. He dealt with rules that didn’t always make sense it is clear he spent too much time pondering them thus leading to his current situation.

Does he like other children still? Not really, he still didn’t know what to do when he touched a kid’s head with a little pat as his backyard picnic with Cain as he wiped his hand on his sweater. Yet, since he has gotten to know Trixie through his interactions with her it is clear that he likes her.

Dr. Linda Martin: Dr. Martin is my fav female character on the entire show as she is a compassionate, caring and intelligent individual and a secret badass. Her relationship with Lucifer started how all of his interactions with people who desire him do - with her wanting to sleep with him. Over time, she realizes that she can’t and shouldn’t be sleeping with him and he also begins to realize that he can work with her without having to pay her with his body and pay her the normal way - with money. He learns to treat himself with more respect and not just give away himself to her. Showing a bit of a shift in how he sees himself with those he actually knows.

I think she really was his first example of how to have a normal human transaction with well, a human. She is incredibly patient with him and even when he reveals his true self to her, she is able to accept him with a little nudge from Maze. Despite being overwhelmed due to his families odd demands on her and almost killed by his very upset and stressed out mother, she protects him as a client and as a friend.

Sure, he always interprets her advice in interesting ways and she knows him well enough to realize that he avoids things and is in denial but she always still cares for him. He also does frequently figure out what she wants him to realize - he just likes to make it more difficult for himself. I wonder if the more that they got to know each other, his ability to influence her waned as she saw him as more than a playboy and he saw her as a doctor who could help him and later as a good and trusted friend.

Most importantly, she never gives up on him and truly believes in him despite all of his detours and distractions. When he has his identity crisis in season 4, she is the first person he shows his devil wings to. This comes from a place of deep trust in her and even though she can’t help him, she is there for him as a friend.

I don’t think he’d ever admit it to her directly, but Lucifer likely understands that Linda’s friendship with Maze has helped Maze grow as a person - er demon - and her advice has helped him in how he interacts with her learning how to change his relationship with her from boss-assistant to more that of peers and friends.

Dan Espinoza: Oh yes, despite all of their stupid male ego headbutting, Lucifer is friends with Dan and he does care for the man. When they first met, Dan was definitely a being a bit of a dick to Chloe; mainly by keeping his own secrets to protect her even though it drove her nuts. If anything bothers Lucifer more it is people lying and hiding things from him. Lucifer is almost pathological with telling the truth and not lying; and well Dan was not the most honest at the beginning.

So of course, he received full on Lucifer hazing; once the police admin punished him by demoting him for messing with evidence he slowly became more sympathetic to Dan. He did use his skills to get Dan to admit that he wanted to correct his mistakes and when Dan started to lose it with Azrael’s blade, he saw that Dan was a stronger and more complicated man than he wanted him to be. If Dan were a simple man, driven by simple desires and actions, Lucifer could write him off. But Dan isn’t, his biggest change is when he realized he needed to stop calling him Detective Douche and actually call him Dan, in part due to Dan standing up to his teasing.

Was it right for Lucifer to keep up his petty antics for so long? Likely not, but Lucifer learned that some of Dan’s actions and personality traits are actually good things and his day shadowing Dan was annoying for poor Dan, but at least allowed him to realize that not everyone is the same.

Lucifer also has been more honest about his feelings in front of Dan than many others - when they went to get a favor from the Russian mob boss, he freely admitted his own hatred for himself and how he hurts everyone he cares about. If he said that in front of Chloe or Ella, both of them would rush to tell him it isn’t true and he’s being too hard on himself. Instead, Dan kept his distance and realized that both of them think the grass is greener on their side of the fence. Lucifer is secretly jealous of Dan’s more simple approach to things and Dan thinks Lucifer truly is careless and wishes he could be a flippant as he appears to be.

Dan really is a reminder how how Lucifer is unable to open up to others and make himself more vulnerable. Unfortunately, this results in Dan frequently getting hurt and he makes epic bad decisions in season 4 out of grief over Charlotte’s death, blaming Lucifer for all of his pain. But no matter what happens, it is clear that Lucifer would not wish for bad things to happen to Dan as he is a good guy and a capable detective.

Is their friendship a perfect one? Far from it, but both of them really do try to care and support the other guy as long as they aren’t pissed off at each other. It likely doesn’t help that Lucifer’s friendship with Dan is pretty much his only one with a normal human guy. He’s got plenty of angelic brothers and Cain really isn’t normal by a long shot so it makes Dan even more important to have him in his circle of close friends. As a 100% totally normal dude, Dan acts frequently as the ‘in’ to understanding (or really lack of understanding) what is happening.

Eve: I just finished re-watching season 4. I’m still not sure where I’d place Eve in all of this. She’s only in season 4 so far and based on her actions, I’m not sure I’d call her one of his close friends. If anything she was pretty much an impediment to all of his relationships - albeit maybe not quite on purpose . . . she’s a woman who still hasn’t figured out who she is despite realizing she needs to not define herself in the context of a relationship.

Sorry for not having more thoughts on this, I need to ponder it more.

What I will say is that their relationship issues stem from the fact that he is an introvert and she’s an extrovert. He realized that Eve was a “bad” influence on him and he struggled to express his feelings to her. The fact that it takes him shouting out at her that he “doesn’t like who he is when he’s with her” was painfully difficult for him to say. It is clear that he cares about her deeply and he wants her to be happy. Yet, he can’t and really doesn’t want to deliver on her actions or feelings. The worst part is that it tears him up inside since in a way he saw her as a possible long term partner which was a big deal for him.

3.) Works either alone or in small groups.

When it comes to his role with the LAPD, Lucifer’s modes of action are not that of a typical extrovert. He is either working closely with his partner Chloe, or occasionally with Ella or Dan. He is never part of a large group nor is he taking a typical leadership role. Due to his need to protect others and his need to get answers as quickly and directly as possible, he frequently goes off on his own. In part, this is so that he can take full advantage of his angelic powers and immortality, but also to protect those he cares about. Sure, he walks into a Korean gang headquarters and tells them to come out, but he doesn’t try to chit chat or smooth things over with them. He goes in, finds the head boss and pretty much strikes a deal with him that he can’t refuse. When he wants an answer his methods are far too direct. Find suspect/target/person and just question them or threaten them and then question them. There is no charming and social games. He can’t be bothered with banal pleasantries when he wants to know something. If Lucifer were a true extrovert he would want to talk to others and feed off of the energy he gets from being with them - yet - he never has shown this. He sees getting information as a task he needs to complete as quickly and efficiently as possible.

Even though he is hurt when Chloe and Cain become closer and begin to hang out or work cases without him, he still shows up and does work to help out with cases. He also is good at working by himself and is able to work things out when he applies himself.

He also has an excellent sense of intuition when reading people. Of course, one of the major aspects of the show is that he projects his own issues onto others. This leads him off of what they are doing sometimes, so his read isn’t quite right. But he is perceptive when he sees odd behaviors and is able to connect things without full information. This is both what he did with Ella’s brother Jay and more importantly with Pierce/Cain. He invites him for a drink and then stabs him with the knife. He looks incredibly nervous after he kills him as he can’t kill a human as an angel - he keeps switching between trying to be calm and have a drink while he waits for him to wake up with a nervous sweat. Did he know for sure Pierce was Cain? No, hence the nervousness until his intuition was proven correct was his true feelings on his gamble.

Furthermore, when he does work with Chloe or others, he always has their back and will go to any length to work with them. This to me indicates that he finds working with a select few people with whom he can trust is how he is most comfortable and he doesn’t need to be the center of attention and the one in charge like how he was in charge of hell. It is clear that by the end of season 4 even though he returned to hell it wasn’t because he enjoyed to or wanted to - it was because he had to protect everyone he cared about. He also has a natural chemistry and ease working with Chloe where even in tough situations they instinctively know what to do and how to act.

4.) He expresses himself through actions.

Lucifer is an incredibly hurt individual. He was punished by having to take a job that he didn’t even want or even desire and most of his family abandoned him. He’s terrified to open up and show his true feelings and pain to others as they would take advantage of it as a weakness to hurt him further. Honestly, I think he still doesn’t quite understand how his actions landed him in hell. He was questioning the establishment and it is clear he thinks deeply about rules and how they influence others. Anything he thinks is illogical he ignores as he can’t be bothered to care to follow those rules and conventions. I think about how he made Chloe rethink the “swear jar” for Trixie - he pointed out rules without a clear basis don’t make sense.

Since he struggles to express his feelings in a way to help others. e.g. mainly in his denial/fear to tell Chloe he truth does two things; i.) he makes it about him or ii.) he tries to demonstrate through his actions.

The making it about him method, is a subtle way where he wants to know how to solve his own problem to help him understand or interact with others. But since he doesn’t want to say for example “I need to figure out how Cain can die since I promised him and I am true to my word.” he instead hides behind the idea of “I need to find the author’s killer so I can read how she got over her writers block.” By extension, since the manuscript is an instruction guide, he thinks he’ll learn something so that he can follow through on his promise. It is a very obtuse way to act, but since he hides behind his narcissistic facade no one will understand he’s not doing it for himself.

As far as his actions, he really shows it when he reorganizes Chloe’s desk; he realizes that she deals with all the paperwork and since she is capable she gets even more paperwork piled on to her workload. He cleans up her mess and anal retentively arranges her pencils and makes sure the right angles on the files are all lined up. He also found a method of filing that makes more sense to him and it inadvertently helps her find the missing piece of evidence for their most recent case. I liked how he color coded everything. Did he need to add the picture of him in his underwear as her backdrop? Hell no, but he figures out that since she likes him, what’s wrong with her seeing a part of him that she likely will never see.

This also gets him into trouble; again, buying the doll for Trixie, trying to out perform Cain in gifts for Chloe and always seeing things as a competition. He wants to give people physical proof of his care for people without actually saying it. Specifically he wants to express his care through a tangible amount of some sort of physical object.

5.) He hides behind his narcissistic behaviors.

As Lucifer struggles to come to terms with himself and expressing his feelings he has hid behind his narcissism. What is a great way to keep people away from you and keeping your distance from them? Being completely self-absorbed with yourself that no one would ever want to be friends with you. His narcissism is a HUGE turnoff for the vast majority of the population.

It is so clear that he wants to develop close relationships but he’s so afraid of hurting others and even more so hurting himself. He’s hid behind his hedonistic behaviors and his self-absorbed actions for thousands of years. He really is a very particular person; he is constantly adjusting his sleeves under his suit coat, his shoes are always perfect, he moisturizes and his hair is styled elegantly. He likes things arranged elegantly and it shows how important control is to him. If he is 100% in control of everything, again he’s protected from being hurt.

As he works at the LAPD and forms his important friendships, his appearance changes. In the first season, he wears black or dark grey suits, his shirts are white, black, dark purple, dark blue and grey, if I recall correctly. He keeps his look simple and professional, almost cold. His matching pocket squares are also basic and mainly a single solid color with few patterns.

Yet overtime, he becomes more adventurous in his appearance, he starts wearing more light blue shirts, he begins to add in more color with burgundy, forest green, and even a caramel colored suit. His pocket squares become more interesting with patterns and more color combinations. With the increase in color and variety he appears much more approachable and has more of an air of friendliness even though he still only cares for his small group of friends.

A case that was a real struggle for him was with the online dating app for “fabulous” people - Top Meet. He wanted to continue to judge people based on superficial appearances, as it has been his own wall and it has served him well. When they ultimately confront the killer, his own knowledge of nature and narcissists allows him to save the day by tossing the head sculpture at him and the detective can apprehend him.

His car serves as both another front and also shows how he longs for few intimate friendships or relationships. He’s got that lovely little Corvette and it is a two-seater. He doesn’t drive a giant, flashy car that can fit lots of people. Instead, he has a small almost cute (I personally think it is cute) car that only another person can sit in. He only wants to ride with one person at a time as he values his close relationships. Yet, having a car that only can fit one other passenger shows a part of his narcissistic front - that only a person who he’d see as worthy would be able to ride with him.

Overall, by looking at how Lucifer chose to have a job on earth in a nightclub where he could simply hide was the first indication he’s an introverted character. The longer he has been in LA, the more close friendships he has formed and they are very important to him as well as his oldest friendship with Maze. When he realized that Maze was attracted to Eve, he noticed it, but hasn’t made mention of it yet (likely that will happen in season 5). The fact that he noticed it meant he really has stopped seeing her as his right hand woman and more just as an individual with feelings. His close friendships really show that he’s an introvert not an extrovert. It is obvious that he gains meaning and connection from these close relationships in a way he never experienced before. His preference for working either alone or in a small team also shows that he is much more comfortable as well as his preference to express himself through actions as opposed to using words since that is much harder and more uncomfortable. Lastly, by hiding himself from all others behind a self-absorbed image he has been able to keep others away from him for thousands of years.

The major point about his character growth is learning that having a small support group of real friends and family he can find what he’s been looking for. A place to belong and be accepted.

#lucifer tv #lucifer #lucifer morningstar #chloe decker #mazikeen #maze #linda martin #dr. linda martin #dan espinoza #ella lopez #trixie decker

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ketopian · 4 years

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Putting Your Money Where Your Research Is

So my wife and I are starting a business selling all the Ketogenic Diet related things that we wish there was already a website for. We've been eating keto for a couple of years now and it has had a huge impact on our health and our lives. My wife has lost a huge amount of body fat and overcome multiple metabolic issues and I've been able to stop taking immunosuppressants for Crohn's Disease and am now completely drug free. We both have hugely increased energy levels. There are loads of great Keto and Low Carb blogs in the world, so I thought long and hard about writing yet another one, but I thought that a) it might help me to get more clarity on certain issues b) give me reason to experiment a bit more with my meals, as I've gotten a bit lazy of late and everyone loves a recipe, and c) force me to consolidate all I have learned from reading various bits of scientific literature in relation to nutrition, which is something I do a lot given my past as a scientist, engineer and science teacher. While my background isn't medicine, I have spent the last few years educating myself on biochemistry. This was originally to help my wife with various issues (many of which a plan to go into at a later date), but I quickly discovered that there was a lot more I could learn.

I, like most scientifically minded or "sceptical" (there's a word that's been seriously corrupted by the internet) people, thought I knew all there was to know about nutrition: a calorie is a calorie, an energy deficit is all you need to lose weight, and no, you aren't fat because of your hormones. I went at least a little further than most; I understood how digestion worked and that starches ended up as glucose in the body, a message some medical professionals still seem to have trouble with. Nonetheless, it came as a shock to me when all this stuff didn't seem to work for my wife. I was seeing how little he was eating, how hungry she was getting and how difficult it was for her to shift those fat stores. Her pregnancy was a major turning point. PCOS had been mooted before but it was never confirmed until a scan ended up with the radiographer saying “Your ovaries look a little polycystic to me”. This was followed a number of weeks later by a diagnosis of Gestational Diabetes, accompanied by the standard advice – eat regular meals (six per day plus snacks) and make sure you have loads of carbohydrate at each – accompanied by the offer of medication. Well, we were both determined that that wasn’t going to happen, so I set about researching, which is what I do best (well, one of two things, but we’ll come to the other much later). The obstetricians could not believe her blood sugar readings – they were better than most non-diabetics. One of them even asked to see the glycometer, as such low readings could not be possible. How did we do it? By ignoring all the advice we were given, reducing carbohydrates to a very low level (although not keto levels at that point) and using a small number of carefully researched supplements. We didn’t mention the supplements to any medical professional; we had enough patronising advice from them, but it was following the science that allowed my wife to avoid medication and to produce a daughter who was born incredibly healthy and with a great start in life.

I don’t want to criticise the medical community too much, most of them are only trying their best, but there is a certain amount of arrogance which tends to come with being a doctor, which often is not concomitant with their intelligence or knowledge. Just as in any other field of endeavour, ability as a medical practitioner is on a bell curve. In other words, there are a few who are fantastic at their jobs, a few who are truly awful, and most are pretty much middling in ability. I’ve taught students who became doctors, and if I were ever given an appointment with them, I’d run a mile! Most doctors follow the guidelines, and it’s a lottery as to whether you get to see the occasional few who do enough research in the right areas to go beyond that. If we educate ourselves to a high enough level, we may be able to help our doctors to help themselves and then eventually to help everyone else.

So back to the story. So this whole pregnancy episode got me really intrigued. Was everything I knew actually complete bullshit? I had spent around close to 300 hours during Hayley’s pregnancy reading papers and getting familiar with the biochemistry and biology of nutrition, and countless more hours not sleeping but thinking about what I had read. It completely changed my attitude to my own knowledge. It had also deeply concerned me. How could everyone have been so wrong on this for so long? Well, it turns out that they absolutely could be, and the reasons are complex and too long for now (stay tuned for a post on this precise subject), but there was something else that intrigued me.

I have Crohn’s Disease. For those of you who don’t know, Crohn’s Disease is an autoimmune disease of the gastrointestinal tract. What this means is it causes inflammation, ulceration and pain, anywhere from the mouth to the anus. It is essentially when your own immune system decides that your gut is a foreign object and therefore needs destruction. My own Crohn’s was mainly confined to the colon, although I also got very large and painful mouth ulcers. Crohn’s is usually treated with steroids, anti-inflammatory drugs, immunosuppressants, which damp down the immune system, and a more recent sort of therapy called biologic therapy. I had been a biologic many years ago, but I was fairly lucky in that I was OK on just anti-inflammatories and immunosuppressants, however the immunosuppressants were not pleasant. I got every illness going. If I got a cold, I had it bad for two weeks, including having to spend a day or two in bed. I had got to the end of my tether; there had to be another way.

Enter ketone bodies. So if you know anything about ketogenic diets you probably know that when you restrict carbohydrates enough that your body starts to use fat to create substances called ketone bodies, the most important of which for human metabolism is a chemical called Beta-hydroxybutyrate (BHB). Well, it turns out BHB has a strong anti-inflammatory effect. “Aha,” I thought to myself,” This might be worth a go”. It was. I had tried to come off medication several times previously, under medical supervision, of course. Always, within about six weeks, I would have a serious and painful relapse. Not this time. I bit the bullet, stopped my medication (this time without telling any medical professionals) stopped the carbs and waited, fully expecting the usual relapse. It’s now been two years drug free and I have never felt better. I would go as far as to say I have no symptoms of Crohn’s. While I would hesitate to say all Crohn’s sufferers should do this, especially the way I did it, it might be worth a try if you’ve had enough of the side effects of your drugs, or if you can’t get any relief and just want an extra bit of help. With medical supervision, of course. It might also be worth a try if you have any other autoimmune disorder, such as ulcerative colitis, rheumatoid arthritis, psoriasis, lupus and maybe even multiple sclerosis. Please don’t take this as medical advice but try to educate yourself and your medical practitioners as much as possible on this subject. If you want any help in this endeavour please let me know.

Well, this has been a long and rambling story, but we’re almost up to date. Since my discoveries I have helped a number of friends and family members send their type 2 diabetes or prediabetes into remission, lose weight and become healthier, both physically and mentally. My wife is slimmer, healthier and feels generally better. I didn’t even realise I had fat to lose but the recent appearance of my abdominal muscles seems to confirm that I actually had a fair bit to get rid of. All by getting rid of refined sugar, starchy carbs and the vast majority of processed foods, and getting BHB levels up. Do I think that everyone should be doing keto? Absolutely not. Everyone’s biology is unique – some people will respond fantastically to a ketogenic diet, some people will get less than nothing from it. But for those for whom it works it is life changing. Hopefully via the website, this blog and the planned videos we will be able to help more people get what they need out of this incredibly powerful dietary intervention.

TL;DR: For lots of people Ketogenic Diets are awesome. Welcome to Ketopian.

#keto #low carb #autoimmunity #crohn's disease #pcos #gestational diabetes #ketogenic #ketopian

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supplier-of-peptidesz · 5 years

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HGH Side Effects, Results, Legality, and More

By George Spellwin

Dear Friend and Fellow Athlete,

For decades, Human Growth Hormone (HGH) has been referred to as the "fountain of youth". It's been used by bodybuilders to cut fat, enhance steroid cycles, and recover from workouts faster. So it's easy to see why many look at HGH as some sort of wonder drug. But just exactly what is HGH? More importantly, what can it do for you, and is HGH safe to use? Keep reading this guide as you'll learn about HGH side effects, HGH results, is HGH legal, HGH vs steroids, and a step by step guide on how to mix HGH - complete with pictures.

What is Human Growth Hormone?

HGH (a.k.a. somatropin or GH) is created by the pituitary gland, and its primary function is to help our bones, muscles, organs, and tissues properly grow during our early years. And it's important that, during childhood and teenage years, your HGH levels remain balanced so that you don't become a dwarf or eight feet tall. HGH benefits don't stop when you're young, though, because you also need plenty of this hormone to keep your muscles full and strong, regulate metabolic functions, have a healthy immune system and repair your skin.

Unfortunately, our body's HGH peaks when we're adolescents and begins to decline from here. This is especially the case when we reach our 30's, as HGH levels begin dropping much faster at this point. Over time this leads to some unsightly byproducts of aging, like more body fat, less muscle, decreased bone density, worse skin appearance, fatigue and decreased brain function.

HGH Results and Benefits

Given all the bad things that happen when our bodies produce less HGH, one huge benefit of this drug is that it can reverse or at least improve aging. Now, this isn't to say that you're going to live to 120 just because you take HGH injections, but you should start to look and feel more youthful by using this drug.

HGH can also help build lean mass. Notice I said "lean" (fat-free) mass because studies have shown that HGH may have little to no impact on muscle growth (1) (2). Even research performed on athletes in training have yielded no proven muscle-building results (3). However, this isn't to say that HGH has absolutely no place in the bodybuilding community because, as I'll later discuss, you can combine it with anabolic-androgenic steroids (AAS) for really powerful results.

This may be especially true in the fat-loss department, where one study revealed that HGH is better than testosterone for melting body fat. The research showed that older men who received HGH injections lost 13% body fat, as compared to the 5.8% fat reduction in the testosterone group (4). Perhaps even more interesting is that those using testosterone and HGH together lost 21% of their body fat.

Another bonus to Human Growth Hormone is that it helps you recover from both workouts and heal from injuries faster. The latter is great for anybody who's dealt with nagging injuries for years that they want to heal finally. As for the faster workout recovery time, well, any athlete can appreciate being able to train harder and more frequently. Imagine how much more muscle you could gain if you worked each muscle group twice every 10 days, rather than the standard of once per week.

HGH Side Effects

As if I haven't already discussed enough great things about HGH, yet another is that you shouldn't experience any side effects with it. Contrast this to AAS, which can have severe side effects depending upon the dosage.

Water retention and joint pain are probably the worst side effects of HGH that you'll experience. Luckily, the joint pain shouldn't be unbearable in most cases, and the water retention will subside when your HGH cycle is over. Some minor problems that you could experience include cold-like symptoms, fatigue, and headaches when using this drug.

One serious issue that you should consider is if your family has a history of cancer. If so, you should definitely visit a doctor and get checked out for cancer because, while GH isn't proven to cause tumors, it can accelerate the growth rate of existing tumors.

Another serious issue is acromegaly, or the thickening of your jaw, fingers, and toes. Acromegaly can lead to the lengthening of your fingers and toes, and cause you to develop the dreaded "square jaw" appearance that many HGH users have - making you look like a hairless Neanderthal However, it should be mentioned that this is normally only a problem in those who abuse high dosages of GH for long periods of time. By keeping dosages reasonable, you should keep your normal human appearance too.

HGH has somewhat of a mixed effect on your cholesterol levels. A study performed on older men and women showed that their LDL (bad) cholesterol levels decreased; however, their triglyceride levels increased (5). One more concern worth mentioning is that those using this drug are also at more risk of developing carpal tunnel syndrome (6).

Is HGH Legal?

HGH is illegal in most countries concerning recreational or performance-enhancing use. In the United States, for example, anybody who illegally sells or prescribes Human Growth Hormones faces up to 5 years in prison and a $250,000 fine. The only way to legally obtain this drug is by getting a prescription for either child growth deficiency or adult growth hormone deficiency. Despite how HGH is not legal in most countries, that doesn't stop many people from getting their hands on it.

Also, keep in mind that all major sports governing bodies have banned GH. Sure, this compound doesn't produce noticeable strength-boosting capabilities (7). But its ability to enhance fat loss, improve workout recovery time, and heal old injuries certainly has some use to athletes. For a while, HGH testing wasn't available to sports leagues because there was no reliable way to test it. However, that's changed quite a bit, and all major professional sports have HGH testing available now.

How to get HGH?

If you don't have a prescription to buy HGH, or a doctor willing to prescribe it to you, then the black market is your other option. There are some underground labs that offer HGH products to anybody through the internet. However, as the term "black market" suggests, you must always be careful when buying HGH online. After all, it could be underdosed, fake, or even an entirely different compound.

One more thing to consider when you buy HGH is that the real version only comes in lyophilized powder, and it must be administered through subcutaneous (into the fat just under the skin) injections. You'll often see some different products offered, ranging from HGH pills to HGH spray - these are complete garbage! Somatropin is a fragile molecule that's really unstable and doesn't stay composed very long at room temperature. If you shake HGH too hard, this can also reshape it and form something entirely different from Human Growth Hormones. Long story short, don't buy HGH pills, patches or sprays.

HGH vs. Steroids

Because Human Growth Hormone and anabolic steroids can both help you build muscle and strength, they are commonly lumped together. However, this is a mistake because they are very different from each other.

First off, HGH is a protein-based hormone produced in the pituitary gland (base of brain). It's made of 191 amino acid chains and controls a number of functions like cell reproduction and repair, and growth of tissue and bones. HGH side effects are typically mild and less threatening than steroids, with the most common problems being high blood pressure, headaches, joint pain, and water retention.

Testosterone, on the other hand, is a sex hormone that's made in the testes. Forming the foundation of all anabolic steroids, testosterone plays a big role in protein synthesis, boosts strength and improves muscular endurance. Anabolic steroid side effects are pretty serious, with users potentially experiencing gynecomastia (man boobs), high blood pressure, high cholesterol, liver toxicity, low sex drive, low natural testosterone and/or water retention.

As you can see, HGH and AAS are quite different from each other in many respects. However, they do share some similarities, namely that they're synthesized naturally in the body, and they're both necessary parts of human development.

HGH for Bodybuilding

Because HGH was and is widely used by bodybuilders and athletes over the years, it's assumed that it has incredible muscle-building and strength-boosting benefits. However, as discussed before, research has yet to conclude that you'll gain any significant muscle mass through HGH (8). But then again, bodybuilders don't take HGH because they've been fooled by public opinion.

This drug has some good effects on fat loss and workout recovery - two huge qualities that bodybuilders benefit from HGH. And these effects are only enhanced when you include GH in an anabolic steroid cycle. Think of AAS as regular-grade gasoline, adding HGH would turn them into higher, premium-grade fuel. You can get better results from anabolic steroids, and use less of them just by incorporating HGH.

So how does HGH work? As mentioned before, GH is secreted by the pituitary gland, usually when you're sleeping or during high-intensity workouts. Once secreted, the activity of HGH normally only lasts for around 10-20 minutes. During this short duration, it binds to fat cells, causing them to break down into triglycerides and preventing these fat cells from uptaking lipids. HGH also binds to muscle cells, leading to the release of growth factors and multiplication of the cells.

Another bodybuilding benefit of HGH is that it travels to the liver and induces the secretion of Insulin-like Growth Factor One (IGF-1). When IGF-1 is released, it stimulates protein synthesis in muscles and encourages amino acid uptake. Research suggests that these actions help to create a moderate anabolic effect that GH lacks on its own (9). IGF-1 also acts very much like insulin and can increase the metabolism of carbohydrates. Higher IGF-1 levels lead to carbs being converted to glucose and used as energy, rather than being stored as fat.

From an overall standpoint, HGH isn't magic for bodybuilders that will help them build pounds of muscle and rapidly drop their body fat into the single digits. However, GH does provide some quality benefits in the way of protein synthesis, nutrient shuttling, and fat loss - all helping you attain a better physique, especially when combined with anabolic steroids.

HGH for Women

Given that most anabolic steroids cause virilization (development of male sexual characteristics) in women, there's a common stereotype that ladies shouldn't use Human Growth Hormone either. But did you know that women actually produce more HGH in their bodies than men?

HGH is safe for women at lower dosages, and they can see some nice results concerning increased energy levels, fat loss, healthier skin, and wrinkle reduction. As indicated in this EliteFitness Forum thread, a good HGH dosage for women without major side effects ranges from 0.5 - 1.5 IU's per day.

HGH Price

Aside from its illegal status, another big roadblock that keeps people from using GH is the high price. It's a great compound to mix with an anabolic steroid cycle...if you can afford it. But for many bodybuilders, it's a little pricey to add just for fat-loss and recovery purposes.

The cost varies based on the brand you're ordering, but it's common to pay anywhere from $3 to $4 per IU of high-quality somatropin. So if you were to buy a supply of 500 IU's, you'd end up paying between $1,500 and $2,000 on average. As I'll discuss below, a typical HGH dosage for bodybuilding is 5 UI's per day, which works out to about $15-$20 for daily use. Maybe you don't have to be a millionaire to afford this, but it's certainly not cheap for a non-muscle building compound.

One more thing to be aware of here: if the price is unbelievable, then don't believe it. Quality HGH - that with 191 amino acid chains - is fairly expensive to produce, so underground labs aren't going to sell it for the same price as Dianabol. If you do find really cheap HGH ($1 or less per IU), it's probably the weak, 192-amino-acid-chain product known as somatrem.

How to use HGH

Okay, so now that we've discussed all the highs and lows of HGH, it should be reiterated that this is an effective drug for certain bodybuilding purposes. This is especially the case when you combine HGH with testosterone, which gives you a great synergistic effect for fat loss and workout recovery. Plus, if you're middle-aged, and beyond, you can't overlook the anti-aging effects of this drug either. That said, let's go over what you'll need to know to run a good HGH cycle by answering some common questions.

What HGH Dosage should I take?

There's no one-size-fits-all formula for how much HGH you should use, and a lot of this has to do with the quality of the product. However, there are some rough guidelines that you can follow until finding out what works for you.

With quality Serostim, you can see pretty good bodybuilding results with just 3-4 UI's a day. With "blue tops" (generic) HGH, you'll probably need 5-6 UI's before you start seeing decent results. If it's really low-quality product, you might even need 7-8 IU's to get the same effect as 3-4 UI's of Serostim.

Assuming you're just using HGH for anti-aging and general health benefits, you can get solid results with only 2-3 UI's per day.

How should I cycle HGH?

As I discussed before, HGH makes for a good drug to stack with AAS. Plus, because this compound doesn't shut down your natural testosterone production like anabolic steroids, you can run it far longer. It's recommended that you use HGH for a minimum of 20 weeks to get solid bodybuilding results.

Again, the quality will greatly determine how much you should use every day. The guy discussed in the thread gets blue tops HGH. Blue tops HGH is a generic made product from China; so I'm betting he's going to need around 5 IU's to get the same results as 3 IU's of a pharma-grade product. As an experienced steroid user, he also stacks HGH with testosterone enanthate, Equipoise, and Dianabol in one cycle, and then testosterone e., Deca Durabolin and Turinabol in another AAS cycle. In all, he runs HGH for 47 straight weeks before stopping use.

When should I take HGH?

When you take HGH, injections will largely depend on your age. Men aged 20 to 50 should release a fair amount of GH at night while they're sleeping; so taking this drug before bed will only suppress your natural output and result in wasted product. That said, most younger and middle-aged men should use HGH in the morning so that you essentially have two HGH spikes - one while you're sleeping and one in the early morning.

For those older than 50, or with a condition that affects a normal release of HGH, you should take it right before bed. This allows your body to mimic the normal pattern of GH release that you'd have with a properly functioning pituitary gland.

How often should I take HGH?

Some people take HGH 7 days a week, which provides good results; however, I don’t think this is necessary. When you get the biggest surge of natural GH in your life, it is during puberty, and it's often in irregular spurts, not a steady source.

A 5 day on / 2 day off pattern is the best route, but most people fall into the (bad) habit of doing it Mon-Fri and then Sat and Sun off - this isn't very good.

This spreads the doses out, but never so you go longer than one day without a dose. I have done it both ways - this schedule and the every day (7 days per week) schedule - and there is really no difference at all with the results...except the above schedule makes your GH supply last longer. Overall, though, the results and benefits are exactly the same. Also, when taking more than 4 IU's of HGH per day, try dividing it into two doses; one in the AM upon rising and the other half at 4 p.m. in the evening.

More than 10 IU's of HGH daily, then divide into four doses: AM, noon, 3 p.m., 6 p.m.

Higher than 10 IU's of HGH daily is not encouraged for the average trainee, and even for the elite trainee until much research has been done. After all, going this high requires T4 supplementation and very often incorporating insulin since the only reason to go higher than 10 UI's of HGH is for forced bulking.

How is HGH Measured?

IU (international units) is a standard measurement concerning amount/quantity, not strength. 10 UI's from a 4mg compound will be weaker than 10 UI's from a 6mg product.

Now consider that when HGH is constituted, we normally use 1ml of bacstat water, which is 100 UI's. So a generic HGH vial that is claimed to be 10 UI's is now effectively 100 UI's due to the water measurement in it. Kind of confusing for sure, which is where I suspect a lot of the complaints about a certain brand of HGH being underdosed originate from. Simply because they do not tell you what strength the product is; instead they hide behind the "IU" claim of so many IU's per vial.

How do I mix HGH?

First of all, you need the following supplies:

One Insulin syringe

One bottle of Bacteriostatic water

One Injection Syringe

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velocitytrimketoreviews-blog · 5 years

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Velocity Trim Keto(updated) >>> *Reviews* 2019

Velocity Trim Keto Reviews experiences

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bayleynichols-blog · 5 years

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The ideal way to take advantage from peptides

So you are hitting the gym for a time now, huh? Likelihood is, youre still seeking to achieve the sort of effects that you see on the telly, in flicks as well as various mags. Well, the best thing is you are really individual, we give you that. Even so, the bad media is - you simply must wait for an 10 years or even more and prepare that time in order to obtain the most out of your requirements and needs. Certainly, additionally, there is a chance to join the dark side and in actual fact use the steroid drugs to ensure the best the process. Even so, this really does imply a bunch of different side effects which can be very unfavorable in the first place. Well, exactly what is the less dangerous different? An issue that enables that you obtain leaner muscle tissue more quickly and with no sort of unwanted effects that will genuinely jeopardize your wellbeing thus making you have problems with different effects? Well, possibly you will find - you only need to know best places to try to find it. If that is true and you're as a result previously exploring the ether expecting picking out the top quality choice, this is the best article for you!

If you're looking for a strategy that may allow you to lose everything that unwanted weight in addition to collect solid granite muscle size while doing so, you came direct at the correct place. You've got to http://www.gopeps.com if you're looking of these benefits. Now, the fact is that these peptides just as the growth hormone truly manifest normally in our physiques and are quite beneficial in lot's more ways than a. So, by way of example, should you be suffering from any kind of issues with your bones or your our bones, it is likely to be an excellent option that will permit you to regain strength and much better your lack of control fairly swiftly. Additionally, unlike nearly all different alternatives which might be just as easily accessible in the marketplace at present, this one is just safe and can deliver so many major positive aspects. Usually the one since you'll be able to complete an item deemed impossible without them - you will definitely have the ability to lose weight in addition to increase muscles simultaneously and you will need correctly is acquire proteins so as to assist in this process without injuring one's body! Needless to say, you are also going to serious about making your research proteins to help make a qualified conclusion in keeping with all of the collected information. Well, the provided option is intending to will give you huge assortment of several solutions and products for the best price ranges. In addition to that, but the most effective direction on-line which will allow you to learn how to start using these peptides on your greatest key gain. Hence, if you'd like for the very best technique to genuinely obtain the most from your requirements and needs in terms of proteins, don't wait to check out the official reference and you may absolutely keep on coming back for more. The resource is very user friendly and, if you're thinking about learning more, will offer you just about any even more guidance that will enable someone to increase your chances of making the very best effort in fitness. Reaching your fitness goals has not been much more clear-cut than that and, as expected, you are likely to keep on wanting more. After all, you undoubtedly are worthy of it! ABOUT US: If you're a serious gym goer, at a certain point you are certainly going to start to wonder how to boost the results you are getting. Guaranteed enough and soon enough steroids will come to mind. Even so, these are way too dangerous with all the achievable complications that might occur there. Consequently, you will have to be off interested in the greatest alternatives that will be much safer and would help you to really make the most from your fitness needs. This is where GoPeps and its peptides come into the game - likely the most reliable option that will let you to make the most from your training. So if you desire to shop for peptides, chances are, you already are conscious of some of their remarkably beneficial aspects and features. Still, here is a fast reminder of what to expect if you are gonna choose peptides and exactly how these will impact your diet, your training as well as your everyday routines in general. So here are some of the main motives why you will like to research peptides as your main go-to solution: - Muscle growth. These days, even if you are not gonna acquire the results you would receive by choosing the anabolic steroids, you are still going to be able to improve your lean muscle mass and will not need just as much time for it. - Fat loss. Peptides will increase your metabolism and you will therefore go on losing fat much sooner and without having to go through an agonizing period when you are stuck at the same weight over and over. - Joints. Right now this is very essential and especially for the athletes who are competing at the time. Healthy joints are part of why you need peptides and HGH in the beginning. So precisely why namely GoPeps and not some other alternative that is just as readily attainable on the market nowadays? Well, examine these out: - Huge variety of products. You have all sorts of HGH and peptides that are bound to assist you in your training as well as within the very least amount of time required. - Licensed products only. You will receive all the licensed products that will not disappoint you. So, if you are searching for that long-desired boost in gains, this is the one option that you are certain to see. ASAP! Contact us on: E-mail: [email protected] US Address: 4116 E15th St Tulsa, OK 74112-6198 Website: https://gopeps.com

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cbdarmour · 3 years

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WHAT DRUGS SHOULD NOT BE TAKEN WITH CBD?

Cannabidiol is almost reaching the peak of its popularity. It is a unique natural compound that is believed to have numerous potential health benefits on the human's body. Many people nowadays choose to go for it as it is organic, devoid of all chemical ingredients and has few to no side effects. This is a claim that has arrested the minds of millions of people though studies are still ongoing and there is only anecdotal evidence as to its both medicinal effects or side reactions.

However, the results that we have at hand nowadays show that CBD oil really may have miraculous influence on our body, yet at the same time may cause drug interactions. The interactions between CBD and other prescription drugs should not be neglected.

So, here is a guide to help you learn more about these drug interactions and feel safe while enjoying the remarkable effects of CBD oil.

When to Take CBD?

CBD oil is one of the hundreds of natural compounds yielded from Cannabis plant. It may be extracted using various methods, but the one that ensures the high-grade final product is the CO2 method. Of the three types of CBD oil (broad-spectrum, full-spectrum and pure) full-spectrum CBD oil is the most effective as it is a combination of cannabinoids, terpenes, flavonoids and, most importantly, THC.

The recent studies of CBD claim that CBD can help ease chronic pain and inflammation, reduce the level of stress and anxiety, minimize the childhood epilepsy seizures (in some cases stop them altogether), treat insomnia, etc. It may surely have a few side effects, which include dry mouth, nausea, fatigue and irritability. But it can never get you "high" or develop addiction.

What Can Amplify CBD's Side Effects?

Taking CBD with over-the-counter or prescription medications with the same side reactions may surely double up the risk of undesirable effects. For example, many medications that can cause sleepiness, such as opioids, antidepressants, antihistamines, alcohol may bring about excessive fatigue, sleepiness, and should be avoided while driving.

On the other hand, stimulants taken with CBD may lead to the loss of appetite and over-emotional condition. The diabetes drugs or heartburn medications may cause diarrhea.

What Potential Drug Interactions Can CBD Cause?

When we take a medication, it is usually metabolized, or broken down throughout our body by the guts, or most importantly by the liver.

CYP 450 enzymes of liver cells do a big part of this process. After consuming CBD products, the functioning of these enzymes slows down or increases leading to either too much or not enough drug concentration in the body. If the process is too slow, it means there is too much of the medication in your system than needed for a long time, which can cause harmful side effects.

Conversely, if the process is too fast, it means you do not have enough of the medication in your body used to treat the health issue. So, a CBD product that you have consumed, over-the-counter medications and the enzyme family interact directly causing drug interaction and hence, unexpected side effects.

The whole family of CYP 450 enzymes take an active part in the metabolism, but it is the CYP3A4 enzyme (anticonvulsants, antiepileptic drugs, and antibiotics) that takes the lead: it is in charge of breaking down about 60 % of the drugs you take. CBD use inhibits the functioning of this enzyme, thus interfering with the process of metabolism and leading to potential interactions.

Which Other Pharmaceutical Drugs Should Be Avoided?

Although there is is still much to be studied, one thing is pretty sure, you should not take any medication that has a grapefruit warning on it. This warning on the label tells you that you should avoid consuming grapefruit or grapefruit juice in sync with CBD and the prescription medication at any cost as it can lead to the concentration of the medicine in the bloodstream, or even overdose.

The most common types of drugs that have grapefruit warning are: antibiotics, antihistamines, cholesterol medications, blood thinner and blood pressure medications, immunosuppressants, pain relief and prostate medications, etc.

Some anti- epilepsy (Clobazam/Norclobazam), anti-cancer ( Etoposide/Teniposide) and blood thinner (Warfarin) medications can backfire when taken with CBD. They cannot be metabolized by CYP 450, which can lead to severe complications, like excessive bleeding, loss of breath, hair loss, more frequent epileptic seizures.

Some sedatives, such as alcohol, barbiturates, benzodiazepines, opiates may interact with CBD. If consumed separately, CBD causes mild sedation, but in combination with the aforementioned sedatives the intoxicating properties of the latter multiply. Though, it would be fair to note, that unlike anti-epilepsy, anticancer drugs sedatives get broken down at least partially, which means that their combination with CBD may not be dangerous.

A thyroid medication (Levothyroxine) may also be affected by CBD products. Some of the potential reactions cannot be predicted, so more research is needed to reveal the severity of these drug interactions.

CBD may also interfere with the medications prescribed for various heart conditions. The list includes beta blockers, calcium channel blockers, nitrates and some statins.

Which Form of CBD Matters More?

Inhaled CBD gets into your bloodstream much faster than any other form(within 30 minutes) and is more likely to increase the severe side effects of the medications.

It takes a longer time for edibles to absorb, so they need more time time to produce a high concentration peak. Yet, this does not mean that eventually their concentration cannot interfere with the prescribed medicine.

Creams and topicals are least likely to interact with over-the-counter drugs as they will not get into your bloodstream sufficiently enough.

All these facts need further investigation as there not enough evidence to back all this up.

Final Thoughts

CBD may potentially interact with prescribed medicine, over-the-counter medications and herbal products. Some side effects may really be acute, while others mild. Drug interactions may depend on several factors: the dose of CBD you are consuming, your underlying chronic medical condition and the dose of the medication.

So, the right thing to do is to consult your doctor first and not to forget to mention all the above mentioned factors. The fact the CBD is natural does not mean it is innocuous, and as you have seen from our guide, if carelessly consumed it can cause severe side reactions.

#CBD's Side Effects #Potential Drug #Pharmaceutical Drugs

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kylieswesting92 · 3 years

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CBD and Caffeine: The Benefits of CBD Coffee

According to the Chicago Tribune, coffee is prevalent among Americans. Roughly 80% of Americans drink it – although the source doesn’t specify which are regular, semi-regular, or occasional consumers.

Many people swear by the potential energizing benefits of CBD, so it naturally looks like an excellent addition to your morning pick-me-up. But what happens when you mix CBD with coffee?

So far, CBD isn’t known for severe side effects, but it can interact with other substances – including alcohol and many medications.

We know caffeine is a stimulant, but CBD is unpredictable. For some, CBD is a relaxant, while others find it energizing. Before you mix CBD and coffee, consider the benefits and drawbacks of this unique duo.

What Happens When You Mix CBD and Coffee?

If you’re wondering whether clinical studies using CBD and Starbucks exist, then we’re sorry to disappoint. However, a 2018 study in the Journal of Internal Medicine suggests a connection between the endocannabinoid system (ECS) and coffee.

In short, the ECS is a system of receptors that interact directly or indirectly with internal cannabinoids (endocannabinoids) or external ones (phytocannabinoids).

The researchers note that cannabinoids and coffee act through many similar pathways. Theoretically, this behavior could support or improve the mutual long-term benefits of CBD in your cup of coffee (more on that later).

Although coffee and cannabinoids travel along similar roads, their impacts differ. Experiments showed coffee decreased endocannabinoid transmitter activity. Cannabis, on the other hand, does the opposite.

But does this make CBD and caffeine complete rivals? Not in the least. While the ECS reacts differently to the effects of caffeine or CBD, the mental and physical experience can mirror both substances.

We’ll get into the common advantages of CBD and coffee later. For now, it’s important to understand what ultimately determines those benefits.

Ingredients Make a Difference

Cannabis isn’t just about THC and CBD. Most cannabidiol products contain additional cannabinoids and oily aromatic plant compounds called terpenes. These substances dictate the therapeutic benefits of CBD. To learn more about the impact of terpenes, check out this article.

CBD’s impact also isn’t straightforward. Caffeine is linear – the more you take, the more hyperactive you feel. But CBD is “biphasic,” meaning it follows a curve pattern, peaking at a certain point and then losing potency as dosage climbs.

Consequently, the effects of CBD oil or other related products are unpredictable.

CBD Types

Speaking of cannabinoids and terpenes, you need to know the basic CBD types before buying anything. There are three categories based on terpene and cannabinoid content:

Full-spectrum CBD contains the same terpenes and cannabinoids as its source plant, including up to 0.3% THC.

Broad-spectrum CBD is similar to full-spectrum, but any THC filters out during processing.

Isolate is up to 99% pure CBD with all other cannabinoids and terpenes removed (not recommended).

We recommend broad-spectrum since it offers the same benefits as its whole-plant counterpart but without THC. To learn more about why you need other cannabinoids and plant compounds, visit our article on the “entourage effect.”

Dosage Matters

Research continues, but we know so far that low doses and high doses of CBD have opposite effects. The amount of cannabidiol you consume can increase energy and alertness or act as a sedative.

Dr. Bonni Goldstein tells Marie Claire: “It’s unclear at this point in time the exact interaction between CBD and caffeine. At low doses, CBD is a stimulant, and in higher doses, it can cause sedation…Someone’s reaction to a combination of these compounds would not be easily predictable because various doses of each would affect the response.”

In other words, the overall effects depend on how much CBD your body needs – and whether you exceed that.

Benefits of Mixing CBD and Caffeine

It rarely crosses our minds, but caffeine isn’t as benign as we think. The drug is well-accepted, but its damaging effects are established.

Irregular heartbeat, anxiety, insomnia, restlessness, and possibly addiction are a few consequences of short or long-term caffeine consumption.

Interestingly, CBD may offer a solution. Not only does caffeine share some pathways with the endocannabinoid system, but it also metabolizes with the same enzymes as CBD.

The combination helps bring out the best in CBD and coffee.

1. Promotes Alertness

Being tired doesn’t just apply to physical exhaustion – although it’s definitely a common symptom. Mental fatigue is as debilitating as physical, with the former often triggering the latter.

Just like a tired body can’t perform its best, a drowsy mind impacts job performance increases stress, hinders communication, and makes every hour feel like a year.

Conventional coping methods include coffee, but some people rely on energy drinks. These sugary beverages are loaded with caffeine, but their effects are short-lived. Within an hour or two, you feel even worse than before.

But as Dr. Goldstein points out earlier, adding a smaller amount of CBD to coffee can amplify its stimulating effects.

2. Extends the Effects of CBD and Caffeine

CBD metabolism is the driving force behind its relationship with caffeine. Again, the drug and CBD share the same metabolic enzymes. So what does this mean? To put it bluntly, this means a heck of a lot.

The conflict creates a bottleneck, as CBD and caffeine compete for the limited room. In turn, this biological traffic jam slows down metabolism, making the effects of CBD and caffeine last longer.

3. No Anxiety or Jitters

For many, caffeine’s side effects can be too much to handle. Anxiety, jitteriness, hyperactivity, and rapid heart rate are some examples that people prefer to avoid. Unfortunately, it can be a tough position for people who just want one or two cups of coffee a day.

Some simply choose to deal with the jitters and other side effects, but that just sets them up for long-term caffeine-related health issues.

But surprised coffee drinkers often say CBD reduced or prevented caffeine’s unpleasant complications.

4. Fewer Bathroom Trips

Does coffee send you to the bathroom seemingly the second you swallow it? You’re not alone. Caffeine is a diuretic, so your body expels it quickly. It increases urination and also irritates your intestinal lining, possibly leading to diarrhea.

Diarrhea occurs due to an inflammatory intestinal response, which prevents the digestive system from absorbing liquid. Coffee works the same way, which is why many people use it to stay regular.

Research on CBD seems promising. A 2016 study in Expert Review of Gastroenterology and Hepatology notes that cannabinoids could be promising for patients with chronic inflammatory bowel diseases (IBDs).

It’s possible that adding CBD to coffee or other caffeinated drinks may help reduce the inflammatory response and prevent diarrhea.

5. Adds Amazing Health Benefits

Although we’re discussing CBD and caffeine, don’t let that cause tunnel vision. Cannabinoids and coffee are just the beginning.

Covering all the suspected advantages would be impossible, but CBD reportedly may help against pain, insomnia, inflammation, anxiety, depression, nausea, and seizures.

Adding CBD also promotes homeostasis – a state of internal balance to ensure the body and mind work properly.

What Coffee Lovers Say About CBD Oil and Caffeine

CBD and coffee may not be on the front page of science journals but seem to be at the front of people’s minds. The niche nature of CBD coffee (or the practice of mixing them) means independent reviews are hard to come by. But Reddit once again pulls through.

According to Reddit user u/juansantona:

“I don’t really feel any crazy difference from CBD in [sic] its own, but when I mix it with coffee, it takes away the dread and the feeling of being strung out. I very highly recommend [it] for anyone who loves coffee but is sensitive to caffeine.”

Below, u/gooslim adds:

“I’ve tried CBD cold brew. It works. It wakes you up, but you feel more focused and less shaky or jittery.”

Side Effects of Mixing CBD Oil With Coffee

We don’t have any research available addressing the side effects of mixing CBD oil with coffee. According to Global Health and Pharma Magazine, cannabidiol and caffeine combined won’t trigger any unpleasant reactions.

However, CBD and coffee have side effects of their own. Any of these could still materialize to different degrees. Ideally, CBD prevents anxiety and hyperactivity from caffeine. But as we mentioned earlier, ingredients and dosage matter.

We’ve discussed caffeine’s complications, but CBD has a few of its own. They’re typically mild and temporary, including:

Drowsiness

Headache

Nausea

Dizziness

Diarrhea

Appetite changes

Choose the right product and dose carefully to reduce the chances of side effects from caffeine or CBD.

How to Make CBD-Infused Coffee

You can upgrade your cups of coffee in two ways. The first option is to buy CBD coffee from a local or online vendor. But there’s a simpler, cheaper solution if you have some CBD products on hand.

CBD Oil

Broad-spectrum and full-spectrum CBD oils are more potent than isolate for combining CBD with coffee.

Use the dropper to add a premeasured dose to your coffee. Ideally, you’ll notice alertness and energy without any jitters or psychoactive effects.

However, CBD oil has an earthy cannabis taste, which offsets the coffee’s flavor.

Isolate Powder or Tincture

Since isolate is pure CBD, all of the aromatic terpenes are gone. This seriously impacts potency but also opens up other opportunities.

For instance, CBD powder and tincture combine well with food and drinks. They’re also flavorless, meaning you’ll enjoy CBD without a “hempy” taste.

Like its full and broad-spectrum cousins, just place the desired dose of isolate into your coffee and stir.

Other CBD Products

You don’t have to make CBD coffee to consume CBD with caffeine – even though it’s arguably the best option. But if you’re not a fan of mixing CBD oil with your chosen roast, you can always get your cannabidiol from other sources.

Colorado Botanicals, one of the leaders in the CBD industry, carries a wide variety of CBD products, including broad-spectrum CBD gummies and CBD softgels that you can take with your morning coffee.

But is it safe, effective, or any different from CBD coffee? Let’s look at some common options.

Can I take Caffeine Pills with CBD Oil?

Yes, you can take caffeine pills with CBD oil. The effects will be identical to consuming CBD with coffee.

Can I Vape CBD and Drink Morning Coffee?

Yes, you can vape CBD and drink morning coffee. However, vaped CBD doesn’t pass through the liver. Consequently, its effects are short-lived compared to CBD oil.

Summary: CBD and Coffee Takeaways

Given the beverage’s popularity, it makes sense to create CBD-infused coffee. Not all substances mix well with cannabidiol, but caffeine and CBD seem to get along.

Arguably the biggest advantage of CBD-infused coffee is its natural counterbalance. If you mix CBD and coffee, odds are you’ll experience all the benefits without the unpleasant side effects of caffeine.

So next time you want some CBD in your cup of coffee, don’t think twice. Not only do you get a better caffeine-like effect, but you support your health in the process.

Sources

AI Global Media. (n.d.). Things You Need to Know About Cbd and Coffee. Global Health & Pharma. Retrieved September 9, 2021, from https://www.ghp-news.com/things-you-need-to-know-about-cbd-and-coffee/.

Cornelis, M. C., Erlund, I., Michelotti, G. A., Herder, C., Westerhuis, J. A., & Tuomilehto, J. (2018). Metabolomic response to Coffee consumption: Application to a three-stage clinical trial. Journal of Internal Medicine, 283(6), 544–557. https://doi.org/10.1111/joim.12737

Drell, C. (2018, August 16). How Hard Should We Lean into This Whole Cbd Coffee Trend? Marie Claire. https://www.marieclaire.com/health-fitness/a22730075/cbd-oil-in-coffee/.

Hasenoehrl, C., Storr, M., & Schicho, R. (2017). Cannabinoids for treating inflammatory bowel diseases: Where are we and where do we go? Expert Review of Gastroenterology & Hepatology, 11(4), 329–337. https://doi.org/10.1080/17474124.2017.1292851

Schumacher, M. (2020, May 29). What are the Benefits of Mixing Cbd and Coffee? Chicago Tribune. Https://www.chicagotribune.com/Marijuana/Sns-Benefits-of-Mixing-Cbd-Coffee-20200529-twtozpiba5advdz4yz76a7kwfm-Story.html.

U.S. National Library of Medicine. (2021, July 2). Caffeine. MedlinePlus. Retrieved September 9, 2021, from https://medlineplus.gov/caffeine.html.

The post CBD and Caffeine: The Benefits of CBD Coffee appeared first on Colorado Botanicals.

from Kylie Westing https://cobocbd.com/cbd-and-caffeine/

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impossiblesandwichtyrant · 3 years

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A Brief Look At dodecyl Benzene Sulfonic Acid

The popularity of dodecyl benzene sulfonic acid has recently increased worldwide. This chemical is known as a synthetic sunscreen, an antiseptic, a deodorizer, an anticancer, and a disinfectant all in one. But these claims are made with a degree of inaccuracy and some people wonder if it's really all that good for you. Before you make the investment, do a little market research to learn more about the benefits and risks of this popular chemical.

Industry Trends There have been increasing reports that suggest dodecyl benzene sulfonic acid is one of the most important ingredients in personal care products such as hand soaps, nail polish, body lotions, facial scrubs, and mouthwashes. It has also been found in cosmetics, shampoos, toothpaste, and hair styling products. dodecyl benzene sulfonic acid was discovered in the United States in a clinical trial for severe acne. Other topical uses include nail polish remover, facial wash, antiseptic, and lip balm.

Industry studies There have been a number of studies that directly compare the skin irritation caused by dodecyl benzene sulfonic acid with that caused by the common sunscreen, benzoyl peroxide. The results were not promising. In fact, a study comparing the irritation caused by the two agents showed a statistically significant difference, with dodecylbenzenesulfonic acid being the more harmful of the two. The authors of the study suggested that people with acne should avoid using products containing benzene sulfonic acid and should immediately switch to a cleanser that contains salicylic acid. Benzoyl peroxide was deemed ineffective in treating either problem.

Research Use There are a number of medical conditions in which the use of salicylic acid is considered therapeutic. Benign skin diseases such as acromegaly and gigantism may benefit from the use of sulphur-based solutions. Some researchers have even recommended its use for psoriasis, but this recommendation is controversial. dodecylbenzene sulfonic acid, like benzoyl peroxide, is considered beneficial for the treatment of acne; however, it has yet to be proven in controlled clinical trials. As with many prescription drugs, there are some questions about the long-term use of sulphur based acne solutions.

Cosmetic Use It's not clear what effect, if any, dodecyl benzene sulfonic acid has on patients who use prescription acne medications. It is believed that the compound may interact with other topical agents and prescription drugs. For example, some patients are given benzoyl peroxide, and when they switch to salicylic acid, their acne flares up. This is not dangerous but finding an alternative can cause problems. Some researchers argue that salicylic acid causes fewer side effects than benzoyl peroxide. No clinical studies have proven these claims.

Skin Reactions In some patients, using sulphur-based acne products triggers a skin rash or other adverse reactions. These reactions appear to be related to the salicylic acid, rather than the benzoyl peroxide. Research use has also shown that the combination of these two chemicals can lead to a flaking sensation on the surface of the skin. This can, in rare cases, cause bleeding and scarring.

Drug Interaction Research suggests that dodecyl benzene sulfonic market player acid and salicylic acid should not be used together. This happens because their chemical properties are too different. When they are combined, the resultant product can cause difficulty for the liver to metabolize. In one case, doctors even reported liver failure. Another important detail is that combining these acids can cause kidney problems, so care should be taken.

If you suspect that you are allergic to dodecyl benzene sulfonic acid, it's always a good idea to consult a dermatologist before using it. The dermatologist will be able to assess your skin and help you determine which treatment is best for your particular condition. Although there is no shortage of information on the Internet, you should nev The research team projects that the Tertiary Dodecyl Mercaptan (TDM) [Tert-Dodecyl Mercaptan] market size will grow from XXX in 2020 to XXX by 2027, at an estimated CAGR of XX. The base year considered for the study is 2020, and the market size is projected from 2020 to 2027.

The prime objective of this report is to help the user understand the market in terms of its definition, segmentation, market potential, influential trends, and the challenges that the market is facing with 10 major regions and 50 major countries. Deep researches and analysis were done during the preparation of the report. The readers will find this report very helpful in understanding the market in depth. The data and the information regarding the market are taken from reliable sources such as websites, annual reports of the companies, journals, and others and were checked and validated by the industry experts. The facts and data are represented in the report using diagrams, graphs, pie charts, and other pictorial representations. This enhances the visual representation and also helps in understanding the facts much better.

By Market Players: Chevronphillips Arkema ISU Sanshin Chemical

By Type TDM Products Based on Dodecene TDM Products Based on Propylene

By Application Styrene–Butadiene Rubber (SBR) Nitrile Rubber (NBR) Acrylonitrile Butadiene Styrene (ABS) Surfactant Others

By Regions/Countries: North America United States Canada Mexico

East Asia China Japan South Korea

Europe Germany United Kingdom France Italy Russia Spain Netherlands Switzerland Poland

South Asia India Pakistan Bangladesh

Southeast Asia Indonesia Thailand Singapore Malaysia Philippines Vietnam Myanmar

Middle East Turkey Saudi Arabia Iran United Arab Emirates Israel Iraq Qatar Kuwait Oman

Africa Nigeria South Africa Egypt Algeria Morocoo

Oceania Australia New Zealand

South America Brazil Argentina Colombia Chile Venezuela Peru Puerto Rico Ecuador

Rest of the World Kazakhstan

Points Covered in The Report The points that are discussed within the report are the major market players that are involved in the market such as market players, raw material suppliers, equipment suppliers, end users, traders, distributors and etc. The complete profile of the companies is mentioned. And the capacity, production, price, revenue, cost, gross, gross margin, sales volume, sales revenue, consumption, growth rate, import, export, supply, future strategies, and the technological developments that they are making are also included within the report. This report analyzed 12 years data history and forecast. The growth factors of the market is discussed in detail wherein the different end users of the market are explained in detail. Data and information by market player, by region, by type, by application and etc, and custom research can be added according to specific requirements. The report contains the SWOT analysis of the market. Finally, the report contains the conclusion part where the opinions of the industrial experts are included.

Key Reasons to Purchase To gain insightful analyses of the market and have comprehensive understanding of the global market and its commercial landscape. Assess the production processes, major issues, and solutions to mitigate the development risk. To understand the most affecting driving and restraining forces in the market and its impact in the global market. Learn about the market strategies that are being adopted by leading respective organizations. To understand the future outlook and prospects for the market. Besides the standard structure reports, we also provide custom research according to specific requirements.

The report focuses on Global, Top 10 Regions and Top 50 Countries Market Size of Tertiary Dodecyl Mercaptan (TDM) [Tert-Dodecyl Mercaptan] 2016-2021, and development forecast 2022-2027 including industries, major players/suppliers worldwide and market share by regions, with company and product introduction, position in the market including their market status and development trend by types and applications which will provide its price and profit status, and marketing status & market growth drivers and challenges, with base year as 2020.

Key Indicators Analysed Market Players & Competitor Analysis: The report covers the key players of the industry including Company Profile, Product Specifications, Production Capacity/Sales, Revenue, Price and Gross Margin 2016-2021 & Sales by Product Types. Global and Regional Market Analysis: The report includes Global & Regional market status and outlook 2022-2027. Further the report provides break down details about each region & countries covered in the report. Identifying its production, consumption, import & export, sales volume & revenue forecast. Market Analysis by Product Type: The report covers majority Product Types in the Tertiary Dodecyl Mercaptan (TDM) [Tert-Dodecyl Mercaptan] Industry, including its product specifcations by each key player, volume, sales by Volume and Value (M USD). Markat Analysis by Application Type: Based on the Tertiary Dodecyl Mercaptan (TDM) [Tert-Dodecyl Mercaptan] Industry and its applications, the market is further sub-segmented into several major Application of its industry. It provides you with the market size, CAGR & forecast by each industry applications. Market Trends: Market key trends which include Increased Competition and Continuous Innovations. Opportunities and Drivers: Identifying the Growing Demands and New Technology Porters Five Force Analysis: The report will provide with the state of competition in industry depending on five basic forces: threat of new entrants, bargaining power of suppliers, bargaining power of buyers, threat of substitute products or services, and existing industry rivalry.

COVID-19 Impact Report covers Impact of Coronavirus COVID-19: Since the COVID-19 virus outbreak in December 2019, the disease has spread to almost every country around the globe with the World Health Organization declaring it a public health emergency. The global impacts of the coronavirus disease 2019 (COVID-19) are already starting to be felt, and will significantly affect the Tertiary Dodecyl Mercaptan (TDM) [Tert-Dodecyl Mercaptan] market in 2021. The outbreak of COVID-19 has brought effects on many aspects, like flight cancellations; travel bans and quarantines; restaurants closed; all indoor/outdoor events restricted; over forty countries state of emergency declared; massive slowing of the supply chain; stock market volatility; falling business confidence, growing panic among the population, and uncertainty about future.

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chin200 · 4 years

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Losing Weight Fast - The Side Effects of Losing Weight Fast

Losing weight rapid is surprisingly in demand today. These are favourite by using many due to the concept of not taking too much effort on diet and exercising yet weight loss continues to be fast.

Who could now not want it besides? The price of the overweight and obese humans is starting to growth extensively which can be very commonplace among teens and adults. However, one need to recognize the real deal of dropping weight in a quick manner as it depends on how have you ever evaluated yourself why have you ever received such weight. The health dangers related to losing weight in a quick manner have to additionally be considered.

Losing weight in all areas is said to be slightly hard. No one has honestly boasted that he misplaced weight and not using a efforts at all. The whole weight loss program, be it in speedy or sluggish manner wishes fantastic deal of sacrifice. It is also sooner or later a warfare against heart illnesses, high levels of cholesterol, stroke, multiplied blood strain (hypertension), breathing problems and a few cancer issues. As such, while the need to lose weight rapid will increase, it would not most effective involve the vanity facet of it, but additionally the avoidance of health issues.

On the opposite word, whilst the want of losing weight accelerated, the choice to lose it rapid isn't always the simplest one on the upward push, because there are products made to be had nowadays to assist humans lose weight. These are dietary supplements that promised desired fitness aim. However, even they promised suitable result, guidelines out of your health care issuer must be sought first.

Goji berry - its call is derived from the maker named Dr. Goji Berry. The content material of the berry is packed with antioxidants that may finally sell short and safe weight loss. Green tea tablets - This is well known for decades now because of its antioxidant content, it flushes out waste from the frame and has effective effects in losing weight. Acai berry - This also popular inside the marketplace due to the fact Acai berry has proven tremendous effects for weight reduction with the aid of growing frame's metabolism, fat oxidization, strength benefit, and maximum of all, it additionally offers powerful antioxidant help just like the two dietary supplements noted above. Alli FDA tablet - This is of course a eating regimen tablet permitted by way of the Food and Drug Administration. These are specifically used for weight reduction with none weight-reduction plan or exercise. As always being highlighted, losing weight is tough specially whilst one desires to be losing weight rapid. However, locating the exceptional and ideal weight loss program and exercising for you can guarantee appropriate bring about weight reduction. As such, it's miles critical to be unique in the preparation period. When you've got made an stock of your self approximately your consuming habits and life-style, you may then determine rightly, and eventually, you may lose weight clean and fast just as what you've got continually been asked for.

The very powerful method: Fast weight Loss = Dedication + The Right Plan

Old ideals always said that you could lose weight at once by means of taking weight-reduction plan drugs, however the new belief contradicts on it and imposes that even to shed pounds rapid, it constantly requires sincere dedication and a way of life change to make your desired purpose appear. You might also have began the short-reduce in losing weight but you found out in the end that you have not misplaced not anything. This is clearly very true because if brief reduce is present, why do human beings spend so much time in the fitness center and sacrificed of not consuming what they continually craved for? Of course, the sacrifice for losing weight will not kill you; it is a be counted of ways you take matters and getting used to it.

Right plan means right choice of food to be positioned into the mouth. When you adore pizza, spaghetti, chook and other fatty foods, it's time to devour absolutely extraordinary types of food. You have to consume greater of lean meats inclusive of in fish and fowl merchandise; eating masses of veggies and only healthy "carbs" are consumed like the whole wheat, grains and rice (brown); and in the end, bear in mind loads of water at the least 3 liters day by day. These are the main elements for a totally healthful way of living but can come up with a fast and natural result.

Right plan also way you are to interact in a health regimen. The thoughts and frame have to be organized bodily and emotionally. Working out for 45 minutes for four days per week with the mixture of cardio sessions and weights are useful. You would have to switch the normal watching of tv and browsing the net to a healthy and efficient approaches which include cleaning the house because it may also assist burn fats and shed pounds. Also, whilst you are much greater relaxed running out at your home, you may accomplish that. You can have brisk walking or running first thing in the morning 1 hour before breakfast.

Your weight loss intention have to now not prevent in dropping the load, but you furthermore may must learn to maintain it off always, which clearly defines an ultimate successful weight loss. However, in as tons as you want to look the end result too fast with out properly guided on nutrition, there are following dangers of dropping weight too speedy.

Water Weight

When we constantly try and shed pounds quick and do the whole thing to hit the goal, the tendency right here is that what you lost is virtually a water weight. So, is that this precise for fitness? Definitely No. Losing water from the body can motive dehydration and the critical electrolyte this is crucial for the heart called potassium is misplaced, which then may additionally cause heart attack.

Remember, water is critical to existence. Drinking a tumbler of water before meal can prevent you from overeating and additionally hydrates your frame. Exercising can triggered you to lose water via perspiration, as such, water is vital to refill the lost water within the frame.

Diarrhea

Another effect of losing weight too speedy is the unsightly diarrhea and observed by way of constipation. When diarrhea is prolonged, extreme dehydration also can manifest that is detrimental and threatening to the body in particular whilst you are using detoxification retailers to lose weight.

Instead of looking to flush all the waste out of your body thru detoxing agents to drop kilos, attempt the herbal manner by means of ingesting healthy and properly balanced food regimen that are rich in fiber.

Malnutrition

Another manner of losing weight fast incorrectly is through starving the frame from ingredients. When not sufficient vitamins are introduced in the frame, excessive malnutrition happens over a length of weeks or months. Those crash diets and fasting are dangerous due to the fact they contain restriction of proteins, carbs, fats and different essential nutrients and mineral wished through the frame.

Next, learn greater about Weight Loss Diet Plans [http://www.Stayslimloseweight.Com/rapidfatloss/weightlossdietplans] and see how they will let you shed pounds speedy.

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the-expert-zone · 4 years

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Is Allulose Keto? A Beginner’s Guide

In the world of sugar alternatives, allulose is a rising star. Unlike some sweeteners, such as sucralose and xylitol, it’s a real monosaccharide sugar. It shares the chemical structure of a typical carbohydrate, but it isn’t metabolized by the body. Research has shown it has no effect on blood glucose levels. This makes it an excellent option for keto dieters.

Allulose: A Rare Sugar

Allulose is often referred to as a “rare sugar” due to its minimal presence in nature. Other natural sweeteners, like stevia, taste sugary for a different reason. Stevia’s sweet taste comes from steviol glycosides, which offer up to 150 times the sweetness of sugar.

Allulose, on the other hand, offers about 70 percent of the sweetness of sugar. While it is less sweet, it still gets the job done.

It was first discovered in the 1940s. Trace amounts exist in a variety of edible substances. These include foods like wheat, raisins, figs, jackfruit, maple syrup, and molasses.

Manufacturers can create it through a natural enzymatic process. In the 1990s, Japanese scientist Ken Izumori identified the enzyme that converts fructose to allulose. This method is still used by companies today.

Most manufacturers are making allulose using corn or beet sugar. They isolate the fructose and turn it into allulose through a process of enzymatic conversion. The enzymes are then removed, which results in a potent and low-calorie sweetener.

Although allulose has been around for a while, companies have only recently begun marketing it as a sweetener or adding it to foods. In 2019, the United States Food and Drug Administration (FDA) gave food manufacturers permission to stop listing allulose as a sugar. It’s still included in carbohydrate counts.

Allulose Sugar and the Keto Diet: An Excellent Low-carb Option

Allulose is sometimes referred to by other names, including pseudo-fructose, d-psicose, or d-allulose. No matter which of these terms appear on the label, allulose is a safe option for keto or other low-carb dietary plans.

A teaspoon of allulose contains about 4 grams of carbs. However, it contains no NET carbs. Net carbs are those that the body can fully break down into glucose. Therefore, allulose is essentially free of carbs.

It’s also free of calories. It contains around 10 percent of the calories in sugar, which amounts to about 0.4 calories per gram. This is too small an amount to worry about even for someone on a strict diet.

The Allulose Experience: The Benefits and the Side Effects

Allulose Benefits

Allulose is relatively new to the holistic scene, and researchers are still studying its benefits. Nonetheless, what we’ve learned so far about this low-calorie sweetener has us excited. Not only does it not impact blood sugar, but it appears to also help improve insulin sensitivity. This makes it a good option for diabetics as well as keto dieters.

One study found that allulose could suppress blood sugar spikes in people with borderline diabetes. The same study found no abnormal or problematic effects caused by long-term ingestion of the sweetener.

Early studies suggest allulose can help us lose weight even if we aren’t maintaining ketosis. During one study, researchers fed rats a high-sugar diet with or without supplemental allulose. The rats that received the allulose demonstrated lower body fat percentages and less weight gain. Studies have also linked allulose to a reduction in fat storage in the liver.

One of the greatest benefits of allulose is psychological. Getting healthy and losing weight takes effort. It can be exhausting at times. You want to look and feel your best, but you don’t want to deprive yourself. Natural sweeteners like allulose provide a way to enjoy delicious treats you love without the guilt.

Allulose Side Effects

We’re happy to report that allulose presents a low risk of side effects. The FDA warns some people may experience gastrointestinal discomfort after consuming large amounts. However, these effects are temporary and not life-threatening.

Researchers performed a gastrointestinal tolerance test to determine how much allulose a human can safely consume. The results showed that an adult up to 132 pounds can consume about 54 grams daily before side effects will begin to show up.

The only other negative of allulose is also a factor with other sugar alternatives. Eating anything sweet increases our sugar cravings. While this isn’t a problem if you stick to allulose, it could be an issue if you feel tempted in other situations.

For example, if you’ve been eating a lot of tasty sweets baked with allulose, you might start craving a sugar-filled dessert the next time you’re out to dinner. You can avoid this problem by enjoying allulose treats in moderation.

Everyone is different. If you’ve never tried allulose, start with a small amount and see how your system reacts.

How to Use Allulose: Making Sweets Keto Style

If you’re a fan of experimenting in the kitchen, you’ll love working with allulose. Although it’s less sweet, allulose tastes much like sugar. It’s texturally similar as well, making it ideal for creamy applications, such as ice cream and cake frosting.

Not only is the sweetener perfect for the keto diet, but it’s also easy to work with. It mimics white sugar in just about every way. For example, it has a similar browning and freezing point as regular sugar.

We and other keto enthusiasts have tested allulose against other types of sweeteners. We’ve noticed it contributes to moist, rich, and even caramelized textures. This makes it ideal for use in cookies and cakes.

As far as measurements, you can compare allulose to erythritol. It measures out about the same way.

Other Low-carb Sweeteners to Consider

If you don’t like using allulose for whatever reason, there are plenty of other keto sweeteners to try. Monk fruit is another low-carb sweetener that ranks high in terms of keto friendliness. It’s also ideal for bakers as it measures the same as sugar when properly blended with erythritol.

There are several other sweeteners that are excellent for keto folks, such as Splenda. However, sweeteners like Splenda often contain other types of sugar, such as dextrose, as fillers. Make sure you carefully read labels to avoid pushing your body out of ketosis.

Figuring out the keto diet can be tricky, but you don’t have to do it alone. Subscribe to our keto blog today, and join our community of passionate keto and low-carb bakers. Whether you’re a beginner or a long-time keto enthusiast, we welcome you.

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smartyrpoetry · 4 years

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Fast Products Of CBD Oil Home Sales Business - New Information

Hemp Oil vs CBD Oil: Which One is the Best Solution for You?

Due to the legalization of hemp in the United States, hemp oil and CBD (cannabidiol) are hot subjects. Although both of them are produced by the exact same plant, they come from different parts of the plant. CBD oil comes from the complete plant. Hemp oil is extracted from the seeds. Hemp oil is likewise oftentimes known as hemp seed oil. Each of them come with numerous health advantages. Hemp is lawful on the federal stage. The states were left to make a decision on their own how to proceed. For anybody who is buying hemp or CBD items, you're not going to have any issues, since those products are legit. Check out your local laws if you really want to grow hemp in the garden. In case you are curious about the differences between hemp and marijuana, they're 2 different versions of the same plant, cannabis sativa. Hemp was cultivated for its strong fibres that are used when making rope. Marijuana was cultivated for leisure uses. Hemp oil is similar to other cooking-type oils and is employed in cooking and skin care items. CBD oil is used in the alternate/holistic medicine area. Hemp and CBD oil can render beneficial benefits: 1. CBD oil has anti-inflammatory effects. CBD oil minimizes swelling through the entire body. Some experts think that all health problems are eventually attributed to inflammation. The anti-inflammatory activity of CBD oil is currently being analyzed in the treatment of Alzheimer's, multiple sclerosis, and Parkinson's. 2. CBD oil may becan certainly be used to lessen pain. Nobody is absolutely certain why CBD oil lessens pain, but it is presumed that it may perhaps be due to the anti-inflammatory benefits. 3. CBD oil can help alleviate anxiety. CBD oil has been shown to be practical in dealing with stress and anxiety. It is understood that CBD oil does this by affecting the level of sensitivity of serotonin receptors in your brain. 4. CBD oil has actually been revealed to be beneficial in dealing with acne. Ingesting CBD oil has been shown to be effective in dealing with acne. Acne is thought to be at least partially caused by inflammation which encourages the overproduction of oil in the sebaceous glands, so relieving that inflammation may be what will help. ◦ CBD oil can also come in useful in the treating of psoriasis and eczema 5. Hemp oil has lots of anti-oxidants and omega-3 fatty acids. Hemp oil is extremely healthy and has a good number of the exact same qualities as fish oil. 6. Hemp oil is a splendid moisturizer for your skin. Hemp oil could be applied directly to your skin. It is even being put to use in numerous readily available skincare items. 7. Neither of them can get you "high." Although both products come from the same species of plant as marijuana, hemp items originate from a variety of the plant which has minimal levels of THC, the substance in cannabis that makes you feel "high". Consider trying hemp protein in case you are feeling really courageous. It is far from the best tasting choice, but it is a healthy, total protein and rich in fibre. CBD oil is usually well-tolerated. Probably the most common side effects consist of diarrhoea, dry mouth, much lower appetite, and fatigue. CBD oil needs to be treated as any other over the counter item. Should the side-effects are too distressing, be sensible and avoid using it. In case you have any fears, stay in touch with your doctor. Hemp oil does not have any unwanted side effects not found in other common food oils. There is still a stigma associated with hemp products, however this is starting to alter with the legalization of hemp in America. Canada has always permitted the growing and processing of hemp. Give consideration to giving CBD oil and hemp oil a go. There are actually several possible amazing advantages with little risks.

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4 of the Top CBD Products For Energy

Cannabidiol (CBD) products have grown in popularity to help manage many ailments, such as pain and anxiety. As research investigating the benefits of CBD continues, some reports suggest that CBD may also be useful as a stimulant and provide a boost in energy.

In this article, we will discuss the effectiveness of CBD in boosting energy and suggest some CBD products and alternatives people may consider trying to feel more energetic.

Is CBD legal? Hemp-derived CBD products with less than 0.3% THC are legal federally but still illegal under some state laws. Cannabis-derived CBD products, on the other hand, are illegal federally but legal under some state laws. Check local legislation, especially when traveling. Also, keep in mind that the Food and Drug Administration (FDA) have not approved nonprescription CBD products, which may be inaccurately labeled.

The human body contains a complex network of neurotransmitters and cannabinoid receptors known as the endocannabinoid system (ECS). Researchers believe the ECS may be involved in many processes, such as energy metabolism and learning and memory.

While people may consider CBD a sedative rather than a stimulant, CBD appears to have a biphasic effect. This means that people may experience different effects or phases depending on the dosage they receive.

According to a 2017 review, lower doses of CBD may have a stimulating effect, while higher doses may have a sedative effect.

https://www.medicalnewstoday.com/articles/cbd-for-energy

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terrykdurham90 · 4 years

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How Insulin Resistance Affects Weight Loss

Although it is an undeniable fact that diet regimen participates in a considerable task in creating folks ending up being overweight, there are actually nonetheless a number of various other aspects which need to have to be thought-about as a result of the truth that they determine body weight gain in one way or even the other.

For example, our metabolic wellness - the state of the various chain reaction related to the creation of energy as well as various other products required to sustain lifestyle coming from consumed food items - may, in fact, be regarded as one major weight-loss variable which is actually certainly not only had an effect on by diet yet just as through other aspects like exercise, worry, and also rest.

The amount and form of food items that a private consumes have a notable part to play in his/her metabolism and also the ability of the body system to make use of those food items. As a means of depiction, higher glycemic mark carb foods are commonly known to be quickly taken in into the bloodstream triggering a practically instant increase in blood glucose level degrees. Once the body system notices an excess volume of blood sugar in the bloodstream, it secretes the hormone insulin from concentrated cells in the pancreas to restore the circumstance as well as in performing, thus preserve its own metabolic wellness.

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Insulin Resistance as well as Effects on Health

According to a lot of health care experts, the outbreaks we are experiencing with being overweight, diabetes, heart attack, and cancer have not occurred without reason. There are actually a pair of incredibly little talked about factors that some researchers have found are adding to a massive component of these health and wellness difficulties.

The hormone insulin resistance, or even Syndrome X, excessive poisonous substances in our food items and drink in the kind of excitotoxins (another subject eventually).

Lots of people have no idea what these pair of complications are actually - or even the degree of the wellness damage our experts are gaining as a result of them!

Listed below is the TRUTH: If our company are ever before going to get control of our health and wellness, our experts MUST understand these pair of concerns!

What is "blood insulin protection?".

The hormone insulin is the hormonal agent "essential" that opens your physical body's tissues, enabling all of them to utilize as energy the glucose or sweets that are in your blood from food digestion of the meals you consume. This capacity to take out glucose coming from the bloodstream as well as convert it to energy is critical to a healthy and balanced body. Your muscles need sugar to perform, and so does your human brain. When you are hormone insulin resistant, your body system's tissues "avoid" the Insulin's effort to metabolize the sugar into useful energy. Even though your physical body is actually gone without food for the glucose, it needs fuel, and it is actually incapable of using the readily available sugar in your blood. Therefore as opposed to being utilized as gas, the sugar builds up in your bloodstream, which causes numerous serious health issues.

What causes the hormone insulin resistance?

Blood insulin protection develops in time from an undesirable way of life and negative consuming practices. A lot of convenience food and chemical-laden processed food items, integrated with tension, inadequate sleep, and a lack of workout, begin to take their toll. A diet regimen being without in thread, complex carbohydrates, fresh vegetables, and fruits, even more, robs your body system of the information it needs to recover from the unsatisfactory diet and unhealthful routines.

Why is blood insulin protection a complication?

If your body system is not able to eliminate the sweets in your blood by shedding it as energy, blood sugar can rise to hazardously higher levels. Long term amounts of high blood glucose level source "poor" cholesterol to rise and your high blood pressure to shoot up. Left behind uncorrected, your body's incapability to make use of Insulin can easily bring on the onset of diabetes mellitus, leading to nerves as well as circulatory harm that may lead to heart attacks, shocks, kidney breakdown, and blindness.

When your physical body cells come to be immune to Insulin and also blood glucose level amounts begin to rise, your pancreatic response-- as it is configured to carry out-- by producing as well as releasing still more Insulin. Way too much the hormone insulin in your bloodstream has two really undesired negative effects: it makes you experience famished (since your body system is actually practically depriving for fuel), and also seeks to reduce the effects of the excess glucose by inducing your body system to stash it as fat! No wonder your every effort to burn fat ends in a breakdown!

Worst of all, if this "the hormone insulin resisting" problem carries on for extremely long, your pancreas can just end up being exhausted from making everything blood insulin and also significantly lessen its result, or even cease completely. It creates the problem known as diabetic issues when that happens. Diabetes mellitus simply indicates your body performs certainly does not produce enough blood insulin. Without the hormone insulin or even medicine to activate the handling of glucose in your body's tissues, the glucose simply accumulates in your blood-- inducing the detrimental nerves and circulatory results defined above.

What is Insulin? The functionality of Insulin.

When the control level of Insulin fails, this failure is going to lead to diabetes mellitus. Thus, the hormone insulin is utilized to manage some forms of diabetic issues Mellitus clinically.

Style 1 diabetics depend on external blood insulin infusing subcutaneously to survive because the system is actually not making hormonal agent no longer.

Style 2 diabetics are blood insulin resisting; this immune perhaps struggles with insulin insufficiency. If other medications fall short of regulating blood sugar levels at a specific degree, although this is quite unheard of, it shows up patients with Type 2 diabetic issues may at some point call for blood insulin.

When you are Insulin insusceptible, your physical body's cells "withstand" the Insulin's attempt to metabolize the glucose into usable gas. When your body system cells come to be insusceptible to the hormone insulin, and also blood stream sweets degrees start to increase, your pancreas answers-- as it is actually scheduled to perform-- through creating and launching still much more Insulin. To a lot of insulin in your bloodstream has a pair of really undesired side impacts: it creates you believe you are starving (given that your body is literally depriving you of energy), and tries to neutralize the excess glucose by triggering your body system to hold it as fatty tissue! Most awful of all, if this "insulin resisting" problem carries on for too long, your pancreatic can merely become fatigued coming from generating all that hormone insulin as well as substantially lessen its output, or even stop altogether. Without the hormone insulin or even medication to switch on the handling of sugar in your body system's tissues, the sugar just creates up in your blood-- leading to the detrimental nerve as well as circulatory effects defined over.

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