#that would be interesting...

[morrigan-sims]

mmmm I have two really really complicated render/edit ideas, and I'm going to die trying to pull them off, but if I can, I will be SO happy.

[unsung-idiot]

don't show him modern technology; it won't end well

bonus under the cut:

[sleepygaymerdisease]

[mangozic]

my dead goth son and his friendly neighborhood personified concept of insanity

[platoapproved]

What was that you said about memory? "A monster," was it?

[rdps01]

close enough

[tizzymcwizzy]

this is a poster i made for my call to action assignment in humanities! it's a bunch of basic and easy stretches for people who sit and work at a desk all day (me)

the idea is that you'd put the poster up above ur desk and do the stretches every 30 minutes or so,, the whole routine won't take more than about 6 minutes to complete and when done regularly it can prevent wrist, shoulder, neck and back pain! :)

all these stretches can be done while sitting (although i HIGHLY recommend you stand up and move around while taking a break from working)

you can get a free digital copy of this poster here on my gumroad!

and you can order a print/poster here from my inprnt!

[avi-mation]

Try not to think about Roomies’ unique quirks in showing affection.

How Etho is bit awkward in showing it but craves physical touch, discovers that forehead touches work for him. And both Cleo and Grian recognise it and put an effort to reciprocate it.

How Grian wants to do things to show his appreciation for his team, it coming out with him bringing trinkets or spending quality time with his loved ones. How both Cleo and Etho accept his need to feel wanted and make sure to always have some physical reminder from their beloved avian.

How Cleo likes to see her boys happy. How sometimes to make it happen, they would manhandle them in the most playful way, with some extra forehead kisses to sweeten the deal.

Now try not to think about it

[buglaur]

[chloesimaginationthings]

Do you think Abby will be scared of Chica in FNAF 2..

[dazzelmethat]

Cricket Cat concept. Do you see it? Do you see my vision? I don't think they'd purr or meow, just chirp with their wings.

[kiisaes]

and it was love at first sight

(this joke comes from the below textpost, but the idea of this being a bkdk meetcute is all thanks to @sapphicflower-ao3)

[ghostedbunnie]

mmm my brain is buzzing with an idea of knight! ghost stumbling upon a carriage getting robbed late at night. appearing like a monster that mothers warn their kids about when they misbehave, mask covering his face and after the bloodbath finishes and no one is left standing but him, he let's out a sigh before making his way to the carriage, one of the window is broken but the heavy curtains are drawn.

when he opens the door he doesn't expect to have the curtains thrown in his face and an absolutely feral maid trying to cut him with the shard of the window held so tight in her shaky hand that the other side cuts deep into her palm. something clicks in place for ghost in that moment, this little cornered thing protecting her mistress with ferocity of a tiger but with fear oozing out of her every pore.

with something that resembles a snort he knocks the shard out of her hand and pulls her out by the scruff as if she truly is just a little kitten showing her claws and he is finding it extremely amusing. the mistress is less of a fighter, he finds, it took one look at him all bloody and dark a picture straight out of nightmares and she passed out on the spot.

with the maid fighting him every step of the way he manages to bring them to his master, his king. turns out the mistress is a princess that was travelling to marry the king and for saving her life, he deserves a gift. anything of his choosing. anyone.

the maid could feel a cold sweat drip down her back when for the first time since they travelled together she heard his voice (she believed his vocabulary was made up of grunts and growls) when he pulled her in with his heavy gloved paw on the back of her neck, "I'll take 'er."

edit: full fic here

[reasonsforhope]

A new treatment combining ReCET and semaglutide could eliminate the need for insulin in type 2 diabetes, with 86% of participants in a study no longer requiring insulin therapy. The treatment was safe and well-tolerated, and further trials are planned to confirm these results.

Groundbreaking research presented at UEG Week 2024 introduces a promising new treatment approach for type 2 diabetes (T2D) that has the potential to greatly reduce or even eliminate the need for insulin therapy.

This innovative approach, which combines a novel procedure known as ReCET (Re-Cellularization via Electroporation Therapy) with semaglutide, resulted in the elimination of insulin therapy for 86% of patients.

Globally, T2D affects 422 million people... While insulin therapy is commonly used to manage blood sugar levels in T2D patients, it can result in side effects... and further complicate diabetes management. [Note: Also very importantly it's fucking bankrupting people who need it!!] A need therefore exists for alternative treatment strategies.

Study Design and Outcomes

The first-in-human study included 14 participants aged 28 to 75 years, with body mass indices ranging from 24 to 40 kg/m². Each participant underwent the ReCET procedure under deep sedation, a treatment intended to improve the body’s sensitivity to its own insulin. Following the procedure, participants adhered to a two-week isocaloric liquid diet, after which semaglutide was gradually titrated up to 1mg/week.

Remarkably, at the 6- and 12-month follow-up, 86% of participants (12 out of 14) no longer required insulin therapy, and this success continued through the 24-month follow-up. In these cases, all patients maintained glycaemic control, with HbA1c levels remaining below 7.5%.

Tolerability and Safety

The maximum dose of semaglutide was well-tolerated by 93% of participants, one individual could not increase to the maximum dose due to nausea. All patients successfully completed the ReCET procedure, and no serious adverse effects were reported.

Dr Celine Busch, lead author of the study, commented, “These findings are very encouraging, suggesting that ReCET is a safe and feasible procedure that, when combined with semaglutide, can effectively eliminate the need for insulin therapy.”

“Unlike drug therapy, which requires daily medication adherence, ReCET is compliance-free [meaning: you don't have to take it every day], addressing the critical issue of ongoing patient adherence in the management of T2D. In addition, the treatment is disease-modifying: it improves the patient’s sensitivity to their own (endogenous) insulin, tackling the root cause of the disease, as opposed to currently available drug therapies, that are at best disease-controlling.”

Looking ahead, the researchers plan to conduct larger randomized controlled trials to further validate these findings. Dr. Busch added, “We are currently conducting the EMINENT-2 trial with the same inclusion and exclusion criteria and administration of semaglutide, but with either a sham procedure or ReCET. This study will also include mechanistic assessments to evaluate the underlying mechanism of ReCET.”

-via SciTechDaily, October 17, 2024

--

Note: If it works even half as well as suggested, this could free so many people from the burden of the ongoing ridiculous cost of insulin. Pharma companies that make insulin can go choke (hopefully).