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Gotu Kola
Scientific Names: Centella asiatica, (synonym Hydrocotyle asiatica), C. coriacea Other Common Names: Indian pennywort or water navelwort, talepetrako, marsh penny Overall Safety: 😐
Therapeutic Efficacy and Considerations:
Flight Microangiopathy: 😐 One trial has demonstrated improvement in ankle edema at various flight durations. More research is warranted, but the current evidence is not sufficient to support a recommendation for this indication.
Venous Hypertension: 😐 Five placebo-controlled trials have all demonstrated decreased edema and symptoms, although patients with mild symptoms did not seem to experience much clinical benefit. More information is needed both on long-term safety and extent of efficacy before a general recommendation can be made. Gota kola may be a possible treatment option in patients with severe edema who have failed or refuse other available therapies. Dose: 30-60 mg triterpenes three times a day.
Sedation/Anxiety: 🙁 Only one preliminary study relating to anxiety has been conducted. It found a reduction in startle response in healthy subjects. Use for sedative or anxiolytic effects is not recommended at this time.
Sedation/Anxiety: 🙁 Only one preliminary study relating to anxiety has been conducted. It found a reduction in startle response in healthy subjects. Use for sedative or anxiolytic effects is not recommended at this time.
Chemistry/Pharmacology: The primary ingredients are triterpenoid saponins, madecassoside, and asiaticoside, as well as asiatic and madecassic acid. Madecassoside and asiaticoside seems to be responsible for decreasing venous pressure and improvements in microcirculation in venous insufficiency. These also have effects in wound healing by decreasing inflammation and glycosaminoglycan and collagen synthesis. Topical application of extracts increases collagen synthesis, intracellular glycoproteins, and mitotic activity and enlarges keratohyalin granules in scar tissue to reduce their appearance. Some antioxidant effects might be responsible for protection of the gastric mucosal lining observed in animal studies. Potential sedative and analgesic effects could be associated with GABA-B receptor binding or increases in GABA. Two other terpenoid constituents, brahmoside and brahminoside, may also be involved with these activities.
Drug Interactions: May have additive effects with sedative drugs; high doses may interfere with the activity of antidiabetic agents, hypolipidemics, and antihypertensive drugs.
Contraindications/Precautions: Pregnancy and lactation (due to lack of information on effects); may elevate blood glucose, triglycerides, and cholesterol levels; may have cross-sensitivity in patients who are allergic to members of the celery family.
Adverse Effects: Hypercholesterolemia, hypertension, hyperglycemia, sedation, GI upset, photosensitivity, hepatotoxicity. Topically: burning sensation, contact dermatitis, or pruritus.
#sigler dietary supplement drug cards#gotu kola#centella asiatica#hydrocotyle asiatica#centella coriacea#indian pennywort#water navalwort#talepetrako#marsh penny#drug facts
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Gotu Kola
Brahma-Buti, Brahma-Manduki, Centella, Centellase, Gota Kola, Gotu Cola, Gotu-Kola, Hydrocotyle, Hydrocotyle Asiatique, Indischer Wassernabel, Idrocotyle, Indian Pennywort, Indian Water Navelwort, Luei Gong Gen, Madecassol, Marsh Penny, Talepetrako, Thick-Leaved Pennywort, Tsubo-kusa, Tungchian, White Rot. Centella asiatica, synonym Hydrocotyle asiatica; Centella coriacea. Family:
Source
The post Gotu Kola appeared first on Health-Info.org.
source https://health-info.org/traditional-chinese-medicine/herbs/gotu-kola/ from Health Info Org https://healthinfoorg.blogspot.com/2019/11/gotu-kola.html
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Gotu Kola
Brahma-Buti, Brahma-Manduki, Centella, Centellase, Gota Kola, Gotu Cola, Gotu-Kola, Hydrocotyle, Hydrocotyle Asiatique, Indischer Wassernabel, Idrocotyle, Indian Pennywort, Indian Water Navelwort, Luei Gong Gen, Madecassol, Marsh Penny, Talepetrako, Thick-Leaved Pennywort, Tsubo-kusa, Tungchian, White Rot. Centella asiatica, synonym Hydrocotyle asiatica; Centella coriacea. Family:
Source
The post Gotu Kola appeared first on Health-Info.org.
from Health-Info.org https://health-info.org/traditional-chinese-medicine/herbs/gotu-kola/ from Health Info Org https://healthinfoorg.tumblr.com/post/189096279554
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Text
Gotu Kola
Brahma-Buti, Brahma-Manduki, Centella, Centellase, Gota Kola, Gotu Cola, Gotu-Kola, Hydrocotyle, Hydrocotyle Asiatique, Indischer Wassernabel, Idrocotyle, Indian Pennywort, Indian Water Navelwort, Luei Gong Gen, Madecassol, Marsh Penny, Talepetrako, Thick-Leaved Pennywort, Tsubo-kusa, Tungchian, White Rot. Centella asiatica, synonym Hydrocotyle asiatica; Centella coriacea. Family:
Source
The post Gotu Kola appeared first on Health-Info.org.
from https://health-info.org/traditional-chinese-medicine/herbs/gotu-kola/
from Health Info Org - Blog https://healthinfoorg.weebly.com/blog/gotu-kola
0 notes
Text
Gotu Kola
Brahma-Buti, Brahma-Manduki, Centella, Centellase, Gota Kola, Gotu Cola, Gotu-Kola, Hydrocotyle, Hydrocotyle Asiatique, Indischer Wassernabel, Idrocotyle, Indian Pennywort, Indian Water Navelwort, Luei Gong Gen, Madecassol, Marsh Penny, Talepetrako, Thick-Leaved Pennywort, Tsubo-kusa, Tungchian, White Rot. Centella asiatica, synonym Hydrocotyle asiatica; Centella coriacea. Family:
Source
The post Gotu Kola appeared first on Health-Info.org.
from Health-Info.org https://health-info.org/traditional-chinese-medicine/herbs/gotu-kola/
0 notes