#small size.

[rottenbrainstuff]

Hey friendos

Well-endowed, ridged tielfing cock = bad dragon Flint.

That is all

[shinseifer]

"average cat owner spends 3 years in prison" factoid actualy just statistical error. average owner spends 0 years in prison. Miette's mother, who kicked her body like the football and went to jail for One Thousand Years is an outlier adn should not have been counted

[foolsocracy]

they barge into justice league meetings saying they have something very important to show them. and do stuff like this

[inoirettes]

sorry for being unactive daddy :(((

[deunmiu-dessie]

older boyfriend!simon who's been pulling out to finish on your thighs since you've started dating. older boyfriend!simon who can't help but want to cum inside of you, especially when your cute little pussy clenches around his cock so greedily. older boyfriend!simon who moans when you cream around the base of him, whining and shaking. older boyfriend!simon who presses a sloppy kiss to your puffy lips when you beg for him to fill you up dazedly, with tear-stained cheeks. older boyfriend!simon who finally gives in. "wan' me t'a stuff y'r pretty pussy with my cum, hm?" ˙ᵕ˙

˖⁺‧₊˚♡˚₊‧⁺˖ - 𝒸𝓁𝒾𝒸𝓀 𝓂𝑒! ⁽ nsfw ⁾

[hilacopter]

tbh ryoko kui cooked with this one why is this the funniest image I have ever seen

[reasonsforhope]

A new treatment combining ReCET and semaglutide could eliminate the need for insulin in type 2 diabetes, with 86% of participants in a study no longer requiring insulin therapy. The treatment was safe and well-tolerated, and further trials are planned to confirm these results.

Groundbreaking research presented at UEG Week 2024 introduces a promising new treatment approach for type 2 diabetes (T2D) that has the potential to greatly reduce or even eliminate the need for insulin therapy.

This innovative approach, which combines a novel procedure known as ReCET (Re-Cellularization via Electroporation Therapy) with semaglutide, resulted in the elimination of insulin therapy for 86% of patients.

Globally, T2D affects 422 million people... While insulin therapy is commonly used to manage blood sugar levels in T2D patients, it can result in side effects... and further complicate diabetes management. [Note: Also very importantly it's fucking bankrupting people who need it!!] A need therefore exists for alternative treatment strategies.

Study Design and Outcomes

The first-in-human study included 14 participants aged 28 to 75 years, with body mass indices ranging from 24 to 40 kg/m². Each participant underwent the ReCET procedure under deep sedation, a treatment intended to improve the body’s sensitivity to its own insulin. Following the procedure, participants adhered to a two-week isocaloric liquid diet, after which semaglutide was gradually titrated up to 1mg/week.

Remarkably, at the 6- and 12-month follow-up, 86% of participants (12 out of 14) no longer required insulin therapy, and this success continued through the 24-month follow-up. In these cases, all patients maintained glycaemic control, with HbA1c levels remaining below 7.5%.

Tolerability and Safety

The maximum dose of semaglutide was well-tolerated by 93% of participants, one individual could not increase to the maximum dose due to nausea. All patients successfully completed the ReCET procedure, and no serious adverse effects were reported.

Dr Celine Busch, lead author of the study, commented, “These findings are very encouraging, suggesting that ReCET is a safe and feasible procedure that, when combined with semaglutide, can effectively eliminate the need for insulin therapy.”

“Unlike drug therapy, which requires daily medication adherence, ReCET is compliance-free [meaning: you don't have to take it every day], addressing the critical issue of ongoing patient adherence in the management of T2D. In addition, the treatment is disease-modifying: it improves the patient’s sensitivity to their own (endogenous) insulin, tackling the root cause of the disease, as opposed to currently available drug therapies, that are at best disease-controlling.”

Looking ahead, the researchers plan to conduct larger randomized controlled trials to further validate these findings. Dr. Busch added, “We are currently conducting the EMINENT-2 trial with the same inclusion and exclusion criteria and administration of semaglutide, but with either a sham procedure or ReCET. This study will also include mechanistic assessments to evaluate the underlying mechanism of ReCET.”

-via SciTechDaily, October 17, 2024

--

Note: If it works even half as well as suggested, this could free so many people from the burden of the ongoing ridiculous cost of insulin. Pharma companies that make insulin can go choke (hopefully).

[tokkimins]

my little lord

[teamfemaleledcuckolds]

[dailyhogz]

Lancelot (Shadow) riding a horse with armor resembling the dark rider

180. horsin around

[astyrra]

joker's 6th part-time job is cat videos

[dead-body-in-the-basement]

A very rare sighting of this DOA trio

[sangled]

pomni: why does the moon call u babygirl

[endivinity]

bane of kings

[mayakern]

hello party people, the sizing survey is back! for real this time!!

as many of y’all know, we are a small business dedicated to creating ethically made, size inclusive clothing! and as we continue to branch out into more kinds of apparel, particularly garments that are more fitted, we need your help to ensure that our garments fit the best they possibly can.

unfortunately, publicly accessible sizing data is horrifically fatphobic and just down right inaccurate. and if our measurements are inaccurate, then the clothing we make won’t fit right. and that’s where you can help!

we want measurements from people of all sizes

all data is completely anonymous and will not be shared

we will only use this data in the pursuit of making the best-fitting garments we possibly can

take the poll here!

[pangur-and-grim]

me and my son