#not so much for insomnia but great for hay fever
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Ily paracetamol ily ibuprofen you make life manageable
#text post#vent#kinda?#idk#im just in pain rn and had to go in a whole anxiety inducing quest to get some paracetamol in me at half 5am#also dw im ok#my legs just for some reason randomly decide to hurt every now and again#usually its not too bad if i catch it early and pre-emptively take some painkillers#but when i cant take it right away- or just dont notice it it can get bad#i guess#i dunno#i cant tell if im over or under selling how much it hurts#ik that even at the lowest end if the pain spectrum it stops me from sleepint lol#shoutout to antihistamines too#miracle workers for hay fever#not so much for insomnia but great for hay fever
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In recognition of 200 followers.....
I composed a list of 200 hero x villain dialogue prompts for you guys to ask me or reblog it and ask your own followers or if you take inspiration.
Thank you so much! It means a whole lot!
1. "I wish I had longer to love you."
2. "Sometimes being the greatest is being the worse."
3. "I will kill you if you die on me."
4. "Bury me... under a willow tree... with tulips and lilies to blossom in the spring and a small stream to keep me company."
5. "Villains aren't capable of love; yet, here I am crying over your grave."
6. "The kitten's name is Max."
7. "I'm going to get a beer."
8. "There is only one way to kill me, but you could never muster the strength to pull through."
9. "I'm dizzy with love for you."
10. "Hero, you are drunk not a toddler."
11. "I pledge to serve you willingly, butthead."
12. "Ride the waves with me." "You are a mermaid, no thanks."
13. "Stay awake for me; it's only a little farther."
14. "I can't carry you!"
15. "He isn't much, but we'll make do."
16. "I WANT TO SEE HER! LET ME SEE HER PLEASE. Please..."
17. "George Washington never told a fib, and I am greater than him, so trust me, Hero, when I say I am telling the truth."
18. "Eggs and butter make dough, knives and guns make death."
19. "You are insane."
20. "The bomb is going off in twenty seconds, Hero. Run now. I-I'm going to stop it."
21. "What is love?"
22. "I don't get the function of hugs."
23. "Mentally I'm good, but physically..."
24. "I only wished for happiness from that genie. I guess it was evil."
25. "Break him, shatter him, destroy him."
26. "Sing with me."
27. "Villain you are touch starved, not dying."
28. "What the heck did you do to your hair." "What? You don't like it?" "It looks like my cat's litterbox."
29. "Don't give me hope."
30. "I am not a disease or a parasite. I am a human. I am one of those millions you swore to protect."
31. "Kiss, marry, kill?" "Kill, kill, kill."
32. "You created me."
33. "Villain don't you dare pass out."
34. "I like the look of blood on you, compliments your eyes."
35. "I kinda dropped Hero through space."
36. "Power exhaustion sucks."
37. "Time to save the world. Yay!" *says in sarcasm*
38. "Let me feed you Hero."
39. "You do not have AC?!"
40. "Villain you have a fever."
41. "Am I drunk?"
42. "Movies. Nine o'clock. Don't be late."
43. "Lemme grab a beer and we are good to go."
44. "Don't. Look. At. Me."
45. "He just had his wisdom teeth out sooo." "How bad can it be? Villain has been shot with twenty tranq darts at one and didn't pass out... immediately anyway, took a good twenty minutes." "Well, you see-" "THE KITTEN IS TRYING TO KILL ME!!!!!"
46. "She needs surgery."
47. "It's a panic attack..." "KISS HIM!"
48. "Blood, gore, madness... this was made for me."
49. "Quit drooling on me and sit up."
50. "There's only one bed."
51. "He looks so cute when he sleeps."
52. "Of all the places to live, you had to choose a heavily fortified medieval castle two thousand years in the past?"
53. "You are a peacock Hero."
54. "Let's see who will drown first. You or me. One, two, three... let's go!"
55. "I wasn't always like this."
56. "Madness is for geniuses, not for me."
57. "It's just a sedative that's going to make you nice and docile."
58. "He's out." "Good, let him rest, villainy is hardwork."
59. "I love her, but she doesn't love me."
60. "If I had a choice to save you or me, I'd pick me."
61. "Gag her."
62. "They aren't made for this, give them mercy."
63. "Talk now or she dies."
64. "Broken ribs, broken jaw, broken arm... are you sure you want me to continue." "No." "Then tell me your name."
65. "Get me some thread and a needle. Just don't touch me."
66. "The police are coming."
67. "Tell me where she is. TELL ME WHERE IS SHE OR I WILL SLASH YOUR THROAT AND TOSS YOU IN THE SEWER!!!!!"
68. "I love you." "I don't."
69. "Hug me just one last time."
70. "Villain hey hey hey. Calm down. You've been in a pretty bad accident."
71. "They won't be able to walk again."
72. "Tell me... just tell if they made it."
73. "Can't you just poof me another arm?"
74. "If you saved all of them, you can save me."
75. "I'm really tired..."
76. "Sleep. I will stay with you."
77. "She is sixteen years old." "All musicians start young." "This isn't a concert, this is life. Stop ruining it."
78. "He"s been in an accident." "Where?" "Five minutes away from your place."
79. "I wish he wasn't unconscious, so I could talk to him. So I could thank him."
80. "It's been four months now. I have came everyday and, uh, I dunno what to say. Hero, I need you to wake up. I can't function knowing you are right here."
81. "I have a date." "Hmm with who?" "Supervillain." "When and where honey?"
82. "Shhhhhhh. Be quiet. We are still being hunted."
83. "Desert?" "What are you trying to do? Kill me?"
84. "I hate you. I hate you. I hate you. I hate you." "I know, I know dear and I so sorry, but I need you to help me. I need you to help them."
85. "Villain just sleep. Allow the drugs to take you under. Don't fight it, don't resist... just sleep. In the morning, we will be safe."
86. "Being lost in the woods isn't ideal."
87. "An injection of valium will do it."
88. "There's no anesthesia."
89. "Wouldn't it be great if we never met each other?"
90. "Bless you." "I didn't sneeze." "Yeah right. Now go sit down, you're sick."
91. "It's called insomnia you dim-wit."
92. "Join me and we can be great."
93. "You didn't bring me here for the cake." "No, dear, but you are so gullible. I brought you here for a sacrifice." "My life?" "Why yes."
94. "I don't know. I never had someone collapse on my doorstep before."
95. "I have nothing to lose. No family, no friends, just my meaningless life."
96. "That's my daughter, not the villain's... so give me her back before I rip your eyes out."
97. "How long was I out for?!" "Ten minutes, but you were drifting. I don't think you had that good of rest." "Oh, I thought I was asleep for hours."
98. "I know, I know you are going to hate me after this, but trust me when I say it's for the best."
99. "I know everything about you."
100. "I think narcissism is contagious because after watching you for a couple hours, I think I may have developed a little crush on the mirror..."
101. "What did you give me?"
102. "Is she screams, I'm going to scream, and then we are going to die."
103. "No fighting today, my cat just died."
104. "How hard did you punch me?"
105. "Not gonna lie, being delirious was epic."
106. "I am cooking for you. You aren't my servant, so stop thinking it."
107. "My old masters made me into a weapon and called me Villain, but if you desire a lapdog I am going to need to be refurnished to fit your needs."
108. "What is his deal?" "I think he's just crazy."
109. "Love is not what I had in mind when I agreed to go on a date with you."
110. "Hugs are overrated."
111. "Are you too hot or too cold?" "Both."
112. "I wish we could turn back time."
113. "I lost the game." "What do you mean? Hero is dead." "Precisely."
114. "Make a wish." "That you live."
115. "Villain has been acting exceptional! Today we granted them a break from the machine. Go ahead Hero and take him for some ice cream."
116. (Sleepy murmurs) "Don't go. I neeeed you." "Yeah yeah I know Villain."
117. "Villain was the one who hurt me, not Hero."
118. "Supervillain is in danger!"
119. "If everyone is scared of me, I might as well be alone."
120. "My head is killing me."
121. "Don't call an ambulance. Just... hold me."
122. "You don't have to do this. It's going to hurt you more than me." "Anything for you dearest, anything at all."
123. "Hero, go wash your hands before dinner."
124. "You have PTSD?" "I don't know?"
125. "I have soap in my eyes!' "Rinse it out." "Mm no I'm permanently mortally blinded." "Uh huh."
126. "We need to cuddle to keep warm."
127. "Take care of them for me, will you?"
128. "When I'm gone, promise to tell my mother, please."
129. "Drug him and then bring him to me."
130. "Superheroes are for children. In all honesty, we are all villains."
131. "Oh my gosh, Hero, what happened?" "Poisoned."
132. "Wouldn't it be nice?" "I don't fancy prosthetics."
133. "Just shut up and listen!"
134. "There is a memorial parade for Hero tomorrow. They asked you to lead it."
135. "She turned it around... at the end."
136. "I wish that he understood how much I care for him."
137. "Civilian! He fell asleep in my lap last night, like totally zooted. It was so cute, but also very tempting. I stuck a french fry up his nose." "Wow. Did he wake up then?" "Yeah, I am sorta kidnapped right now..."
138. "The book, the sword... all pieces of the puzzle huh." "No, darling, all pieces of my game."
139. "Their death is my fault! Not your's, but mine, so quit trying to make me feel better."
140. "Once upon a time-" "Oh please, not another fairytale."
141. "If only it was that easy."
142. "We are stuck in a maze, how can you be so joyful?"
143. "Celebrate Hero, eat your cake, party into the night... but just know, I will be back."
144. "Call 911!" "Why?" "I stubbed my toe."
145. "Your jawline looks like it was gauzed over in lard." "It looks better than your hay for hair."
146. "You're my best friend." "Villain? Are you on drugs?"
147. "Lay him there and leave him. Let the rats dine on him."
148. "The point of the cow suit?" "Oh, uh, I was at a Halloween parade. You know, for children."
149. "I-i never wanted to hurt you." "I know, I wanted you to, so I allowed it."
150. "Favorite movie?" "Your death." "Ooo never heard of it, let's watch it." "*groans* Oh my gosh, you are stupid."
151. "Being a flutist is my only superpower. And being modest apparently."
152. "Your head will join my collection if yoi don't watch out."
153. "Hey, hey! Wake up, buddy. It's just a nightmare."
154. "Meh head hurts." "Yeah, you hit it pretty hard."
155. "Let's go for a ride." "On that yellow miniature school bus?" "It's a ranger you idiot."
156. "No painkillers, no bandages, perfect environment for infection to settle... I'm just gonna leave you here Villain."
157. "I save you and this is how you repay me? A prison?"
158. "What are you doing?" "Climbing a tree? No Hero, I am breaking into your house to kidnap you."
159. "I formally apologize."
160. "Of all places, Hero, you had to teleport us to a desert. A DESERT."
161. "Supervillain won't stop unless we team up." "I don't think our alliance will stop them, I think it'll just make them angrier."
162. "Stop singing or I will blow this place until even the last atom is broken into itty-bitty molecules!" "That... that is scientifically impossible."
163. "I'm a genius! Yippee!"
164. "Life isn't perfect and nor is your morals."
165. "Control yourself before you kill everyone around you."
166. "Say your goodbyes."
167. "Of all the ways I've died, drowning was by far the nicest."
168. "Love the collar. Is it for fashion purposes?" "Uh, um, uh, er, no?"
169. "You look lonely. Want some hot coco?"
170. "It is negative million out there and you expect me to come in toasty warm after fixing your power?"
171. "Are you sick?" "Yeh." "Come on in then."
172. "Civilian, don't even bother trying to save him."
173. "We have a breach!"
174. "What makes a villain's life less important than your's?"
175. "Enjoy your soup." "You poisoned it." "And you're delusional, eat up."
176. "I hate 99% of the population." "According to a meme I found, you are therefore a cat."
177. "Don't overuse your powers."
178. "This is just an unfortunate event."
179. "You look so cute when you are sleepy and barely conscious."
180. "His fever is rising."
181. "Save her, leave me. I'll-i'll get out of this somehow."
182. "Sometimes self-sacrifice isn't noble, it's selfish."
183. "You are so funny that I need my inhaler to kill you with." "That sentence was so discombobulated that I am leaving."
184. "Just for your information, I hate oranges but love grapes."
185. "Walking down the stairs shouldn't be a momental effort." "You broke both your legs."
186. "You just destroyed my life's work, don't expect me to give you a huge bear hug."
187. "Is it true that you have telekinesis?" "Yes, why?" "Go steal me a donut."
188. "You are so incredibly touch starved, Villain." "Mmm." "Tired? Go ahead and sleep, I'm here."
189. "This is for your own good, I promise."
190. "I'm cold."
191. "I don't want to move and you can't make me."
192. "I AM RETIRED! YOU DON'T NEED TO CONTINUE TO SEND ME PAMPHLETS OF THE HOTTEST HERO OF THE YEAR!"
193. "He's unconscious." "That tired, huh." "No, he passed out from blood loss."
194. "I want a kitten."
195. "I'm no scared of you, so stop acting like I am."
196. "He isn't dangerous, just scared."
197. "They won't be going anywhere for a long, long time."
198. "Hero? Hero? Oh my goodness, please wake up."
199. "Life is too short for pleasures."
200. "I hope you are happy, in the end."
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Benadryl for Dogs – Can you Give it? Is it Safe? What Dosage?
Most people have heard of and have probably taken Benadryl before. It’s a great way to treat a range of human conditions including hay fever, motion sickness and allergies, but – is Benadryl safe for dogs?
If you take your dog to a vet with a condition such as swelling or itching, it’s common for them to recommend giving Benadryl to your pet to help them feel more comfortable.
While it’s always important to listen to your vet and realize that they really do know best, this recommendation for human medication does still leave many dog owners wondering how safe it is to give their pet medicine designed for human consumption.
This article has been created to help you understand what this drug is designed to do, and whether or not it is an effective and safe medicine for dogs.
What is Benadryl?
Benadryl is an antihistamine which, in humans, is used to help get rid of a wide range of complaints. The name of the drug used in Benadryl is Diphenhydramine, and there are quite a few other brands that also use this drug, including Nytol, Panadol and Benylin.
There’s an enormous range of Benadryl products available from pharmacies, but most forms of the antihistamine also contain the active ingredient Cetirizine (another form of antihistamine), and some also contain Acetaminophen and Pseudoephedrine.
These last two ingredients, Acetaminophen and Pseudoephedrine, are not safe for dogs!
Because of the availability of different products from the Benadryl brand, if your vet recommends you give it to your dog, remember to ask which form you should be giving them. Also, make sure you read the labels of the products carefully before buying.
We will cover pill and liquid forms later in the article.
What is Benadryl For? What Can it treat?
Because it is an antihistamine, most people take it because of allergies such as hay fever, or to minimize irritation caused by allergy to pets, etc.
There are, though, a whole host of complaints tackled by this drug that most people are less aware of, including:
Swelling
Vomiting
Hives
Hyperactivity
Travel sickness
Insomnia
Anxiety and stress
How Does Benadryl Work?
When we are affected by any allergy or inflammation, our body’s natural defense is to release a chemical called Histamine.
While this chemical is designed to help us recover from the original problem, unfortunately, it does cause a host of issues itself for most people.
Swelling, itchiness, increased heart rate and even increased stomach acid secretion are all reactions to the natural chemical Histamine.
When Histamine releases into our bodies, it can attach itself to 2 different types of receptors – H1 or H2.
If it reaches the H1 receptors, you might experience symptoms like itching, swelling or difficulty breathing.
H2 receptors cause a very different reaction, with symptoms being linked to heart rate and acid secretions in the stomach increasing.
Although there are huge differences between humans and our canine friends, dogs also have H1 and H2 receptors in their body, that respond in very similar ways to the ones found in people.
To help combat the unwanted symptoms caused by our production of Histamine, many people opt to take an Antihistamine drug, which helps block the actions of the Histamine chemical and relieves us of the symptoms.
This is the same reason dogs are prescribed the drug – to help relieve reactionary symptoms to Histamine.
There are several types of antihistamine drugs, designed to tackle the varied symptoms people face. Benadryl is a brand of Diphenhydramine, which is excellent for reducing problems like itchiness and swelling caused by the H1 receptors.
Benadryl is designed to counteract the problems caused by H1 receptors only, so this drug is not useful for tackling increased heart rate or issues with stomach acid.
Can I Give My Dog Benadryl? Is Benadryl Safe for Dogs?
Vets recommend Benadryl for dogs on a fairly regular basis, so the very broad answer to this question is, yes – in SOME situations, Benadryl is safe to give to dogs.
There are, though, a lot of things you need to check carefully before you go ahead and administer this drug to your pet.
The most important thing to look for is that the particular Benadryl product you have only contains Diphenhydramine.
Cetirizine is an active ingredient in some Benadryl products that can be used for dogs in specific circumstances, but it won’t treat the issues present if your vet has recommended Benadryl.
So steer clear of any products also containing Cetirizine, there’s no need to expose your dog to unnecessary drugs that won’t help them!
Acetaminophen and Pseudoephedrine are also found in some Benadryl products, and while these are a great addition for humans, they are not safe for dogs. If given to dogs, these drugs are considered to be toxins.
The most common problems caused by these two additional drugs are liver damage, and increased heart rate and blood pressure. So just be very careful to look at the ingredients in the product you are hoping to buy.
Even if you’re happy that you have the right product to give to your pet, you simply must still speak to your vet before ever administering it.
There are circumstances where this drug would not be recommended, so get a professional opinion before ever giving it a try.
Can you Give Dogs Benadryl Made for Human Consumption?
There are currently no products of this nature made specifically for dogs, so if your vet does recommend it, the medication made for humans is the only available ‘over the counter’ option.
Currently, the FDA have not approved the use of Benadryl for dogs. However, it is commonly recommended by vets because of its ability to help relieve a range of issues with very few significant side effects.
Make sure you only administer the type of product advised by your vet – the time-release capsules, for example, are a very popular form of the medication for humans, but for dogs they can because a health risk.
If you do give your dog a capsule, they’re likely to receive a dose that’s too high if they chew it, and if swallowed whole, it’s unlikely it will be properly digested which could result in another trip to the vet!
What Specific Things Can Benadryl Treat in Dogs?
Food Allergies
Always check with your vet that any allergies aren’t causing your dog more serious issues, but if this isn’t the case, Benadryl is commonly recommended for this reason.
Bee Stings and Insect Bites
If your dog is not having a severe reaction to a sting or bite, Benadryl can be used to help relieve the irritation caused by common critters.
Hives
Benadryl won’t get rid of hives quicker than they would normally disappear on their own, but the drug can make your dog much more comfortable while hives are present.
Reactions to Vaccinations
Some vets recommend giving a dose of Benadryl before arriving for vaccinations to help prevent the onset of any side effects or discomfort caused by the injection.
Calming During Thunderstorms and Fireworks
The drug has a calming effect on dogs and will often make them sleepy and sedated, so it can be useful if your dog finds occasions like storms or fireworks stressful.
If you know there’s an occasion like this coming up, speak to your vet, and stock up on the medication in advance to help keep your dog calm and settled!
Motion Sickness
Because of the effects on the brain and nervous system, this drug is commonly recommended to combat motion sickness.
Benadryl takes about 30 minutes to take effect, so if traveling is an issue, remember to administer the dose half an hour before setting off.
Before Flying
Being helpful for both motion sickness and calming dogs makes Benadryl good medicine to administer before flying to help them pass the time quickly and calmly.
Benadryl Dosage for Dogs – How Much Should You Give a Dog?
Before using any dosage guidelines, make sure you check with your vet, as there is a range of circumstances that might change the amount you should administer.
For a healthy dog, you should weigh them, and per 1 pound of body weight, you should administer 1mg of Benadryl (referring to the products only containing diphenhydramine).
The average size of a Benadryl tablet is 25mg, so if you have a 25-pound dog, you should give them 1 tablet.
In rare occasions such as in response to a snake bite, a single dose may need to be doubled to help make your dog comfortable.
Obviously, if you think your dog has been bitten by a snake, emergency veterinary advice is required.
How Often Can You Give a Dog Benadryl?
The recommended dosage for dogs is the correct amount administered 2 or 3 times per day, with a gap of 8 to 12 hours between doses.
Benadryl should not be given to your pet more than 3 times in any 1 day.
If your vet has recommended giving your dog the drug for a set number of days, make sure you complete the course suggested and don’t stop giving it if your pet starts to seem better.
It may be that the antihistamine is just making them more comfortable and able to cope better with their original symptoms.
If you use Benadryl for dogs on a long term basis, be aware that the effectiveness might start to lessen over time.
If your dog has a condition that needs antihistamines to treat them over a longer period of time, ask your vet for other antihistamine products that you can ‘swap in’ to give them a break from the Benadryl.
Benadryl for Dogs Side Effects
As with any medication, there is a range of side effects that may affect your dog.
Every animal (and human) can respond to drugs differently, so your pet may experience none, some or all of these symptoms:
Sleepiness / sedation
Lack of interest in food
Diarrhoea
Sickness
Producing less urine than usual
Dry mouth
If your dog seems to be having a strong reaction to Benadryl, it may be that they’re very sensitive to it, so speak to your vet again for recommendations of different forms of medication to try.
What Dogs Should NOT be Given Benadryl?
If your dog has any existing disorders or is already taking medication, it may not be recommended for them to take Benadryl.
You shouldn’t administer the drug to your dog if they have any of the following conditions, or have suffered from them in the past:
Lung disease
Heart disease
Glaucoma
High blood pressure
Enlarged prostate
Known sensitivity to diphenhydramine
Pregnancy is also something to consider – the complications caused by needing medication during pregnancy are very similar to those we see in humans!
In general, medication that’s not essential should be avoided to try to keep the unborn puppies as healthy as possible during gestation.
It is not recommended that you administer Benadryl to a pregnant dog, but depending on the individual circumstances, your vet may decide that the need outweighs the risks.
Just make sure you’re very clear in your consultation that your dog is, or may be pregnant if this is the case.
Can You Give A Dog Liquid Benadryl?
Benadryl produce a liquid form of the medicine, and the one specifically designed for children can also be given to dogs as it is alcohol free.
If you decide to use the liquid form, do make sure you work out the correct dosage.
5ml of liquid Benadryl medication should contain 12.5mg of diphenhydramine, and the dosage should be worked out at 0.4ml of medicine per pound of your dog’s weight.
Can You Give A Dog Benadryl Pills?
It is safe to give your dog Benadryl in the form of a pill, as long as it is not the slow-release capsule form.
Check the label carefully to make sure you have selected the right product from the Benadryl range.
How to Give Your Dog Benadryl
If you opt for Benadryl in a pill form, the easiest way to get your dog to swallow them is by hiding it in their food. Most dogs will swallow tablets like this without any issues.
If your dog is more particular and notices you’re trying to sneak something into their dinner, you may need to try a tastier treat to hide it in!
Give them their favorite food, making sure they eat some of the non-medicated portion first, so they don’t realize something is different.
You can also play with your dog and get them to catch a treat if you’re struggling to get them to take pills.
If you can hide their tablet in something tasty that you can throw, just give them a few treats to catch, and sneak the medication into one of the chunks.
If you’re opting for the liquid form rather than pills, the easiest and most accurate way to administer it to your dog is by using a syringe.
It’s very easy to measure out the correct dosage using this method, and most dogs are happy to take the fluid this way.
If you have issues getting your dog to take medication from a syringe, try training them to take water from one first so they get used to the process and sensation of it being squirted into their mouths.
Once they are trained, if you do need to administer medication, they shouldn’t notice the change from water to medicine enough for it to bother them.
Can a Dog Overdose on Benadryl? What to Look for, What to Do?
It is possible for dogs to overdose on Benadryl, and if they do, the consequences can be severe.
If you think your dog may have overdosed on the drug, contact your vet immediately to seek further advice.
If you can get your dog to a professional quickly after a possible overdose, it’s likely they will be able to recover. Cases have been reported of dogs surviving a dosage 16 times higher than recommended with immediate hospital treatment.
Common symptoms that your dog may have received too much of the drug are:
Difficulty breathing
Fast or irregular heartbeat
Tremoring muscles / muscle spasms
High temperature
Extreme fatigue
A less common side effect of overdosing on this drug is also high blood pressure, which may lead to seizures and other more serious issues.
Conclusion
If you feel your dog may benefit from taking Benadryl, the most important thing to remember is to speak to your vet first. Discuss their symptoms and medical history to discover whether this medication is best.
Don’t make this decision yourself; it must be the advice and decision of your vet!
If you’re unsure about the dosage to give your dog, your vet will easily be able to advise you. They can give you an up to date weight for your pet, and tell you what that translates to in mg or ml of the medication.
Under the direction of a vet, Benadryl is generally a very safe drug to give to dogs, and can offer relief for a huge range of symptoms.
Serious side effects are extremely rare, and usually easy to treat, so just monitor your dog carefully if you’re administering the drug for the first time.
With Benadryl only taking 30 minutes to take effect, you should see your dog settle down and become less concerned with their symptoms relatively quickly, so you can relax knowing they’re as comfortable as possible.
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Commander Saturn (Saturnalia)
There is no consistent personality for Saturn. He’s going to be completely different wherever you find him.
His game version (and therefore the Generations version) was organized, dependable, and somebody Cyrus apparently trusted enough to leave the organization to in case things went wrong. When I wrote Koyaanisqatsi, I tried to channel that version, along with his disillusioned comments in the Platinum end-game about how “extremism never solves anything.”
His anime version showed some of these traits, but we saw so little of him.
If you use his Special/Adventures version, he’s an agoraphobic man-child who loves to play video games and remotely torment people with his gadgets. The fact he puts tape on the floor and gets peeved each time Mars encroaches on it makes me laugh every time.
In Diamond Pearl Adventure, he’s fiercely loyal to Cyrus: even to the point of begging for a chance to redeem himself when he loses to Hareta. He’s a capable battler (more so than any Commander other than Mitsumi), and also clever enough to play a double agent role during Charon’s takeover so he can rescue Cyrus.
Although Saturn’s personality is all over the place, that loyalty and desire to support Team Galactic rang true in all his iterations. I decided to focus on that when designing his fragrance. It wasn’t so much about how the oils smell in Saturn’s case, but what the oils do. And hoo boy, do they do a LOT...
Saturn’s synergy (Saturnalia) promotes a relaxing, calming effect and soothes tired muscles after a stressful, frustrating day. Many of the oils inside the blend are good for alleviating physical pain, but two of the oils in this synergy are also fantastic for anxiety and insomnia.
The main note in Saturnalia is Roman Chamomile. There are two types of chamomile you can purchase in essential oil form: German and Roman. They both smell like a cup of chamomile tea by themselves, but the Roman is a little stronger and has more of a sedative effect. That and my cat loves the Roman Chamomile, so I keep buying it.
But since I wanted to give his more dimensions than just a tea dupe, I took a look in my inventory to see if I had any other cool, calming oils that would blend well with the chamomile, give me the results I wanted, and—I did!
The next oil I added to the blend was Sweet Marjoram, which has given me really good results with my back problems in the past. The problem then was that poor Saturn’s blend now smelled like delicious Greek food rather than something anyone would want to wear as a cologne. I wasn’t anywhere remotely near done!
So in went the Juniper Berry (the key ingredient in gin) for a cooling effect, paired with woodsy Blue Cypress and medicinally floral Blue Tansy.
The end result was a “hot cup of tea on a cold rainy day” sensation for my muscles and nose. I could feel the oils soaking in through my skin and the water turned a dramatic sapphire blue.
I got the support I needed from this blend. My back (my biggest pain area) felt spry and healthy the following morning. My dreams were pleasant. I didn’t wake up seven to eight times in the night due to pain or bad dreams. It was a soothing, calming experience from start to finish.
Now it’s time to talk about the pros and cons of these oils from a safety perspective…
Aromatherapy isn’t just about pretty smells and scented bath water. Essential oils are in such a high concentration that even absorbing them through your skin can leave you with the therapeutic (and potentially toxic) benefits.
If you are allergic to a plant, you are 100% without question going to be super allergic to the essential oil.
There’s also such a thing as contraindications: where some oils may affect you in weird ways if you have a certain medical condition or take certain medications.
The information below is for your safety if you want to attempt to make this blend at home (as a bath bomb, a body spray, or even scented bath salts). And do be sure to wear gloves. Some of these oils have recommended dilution rates as small as 0.4%. You don’t want that to slide on bare skin!
Roman Chamomile
There are actually two true chamomile Essential Oils on the market: German and Roman. Roman is the more potent of the two, so I mixed it into this blend. It worked. That bath bomb had me in bed by 8:00 PM because I was so sleepy afterwards!
Pros:
It’s one of the safest Essential Oils to diffuse around your kitty! While no Essential Oil is truly safe for a cat and you should always leave the door open so your kitty can escape if you’re using Essential Oils, Roman and German Chamomile are two of the least harmful for your feline friend. My kitty Gaius loves the smell, so I’m saving up to get it in Hydrosol form.
Fight off insomnia! If you’ve ever had a good calming cup of Chamomile or Sleepytime tea (Celestial Seasonings), then you are already familiar with the relaxing properties of Roman Chamomile. This Essential Oil (especially when mixed with other soothing scents like Lavender or Lily of the Valley) promotes a calm, peaceful atmosphere which makes it so much easier to sleep. It works for me, and I’m sure it’ll work for you!
Feeling nauseous due to stress? Fix it with Roman Chamomile! Roman Chamomile can be used for various stress-induced digestive disorders including indigestion, upset stomach, nausea, vomiting, loss of appetite, and bloating from gas.
Chamomile can be a girl’s best friend! A lot of women use Roman Chamomile (especially in tea form) for morning sickness and really painful menstrual cramps. It’s considered to be a “blood purifier” and general female tonic, reducing menstrual pain and better regulating periods.
Relieve pain and swelling! Roman Chamomile is great for reducing pain and swelling of the mucus membranes, sinuses, and joints. It can also be mixed into lotion and applied to the skin for swollen, inflamed areas. It can also be used on wounds, burns, eczema, frostbite, bedsores, hemorrhoids, and diaper rash.
Diffuse it to help your sinuses! Roman Chamomile can be diffused and inhaled for sinus inflammation, hay fever, sore throat (something I’m battling right now), and ear inflammations.
Cons:
Since Roman Chamomile can stimulate a period, pregnant women should avoid this oil to reduce their chances of a miscarriage.
Since Roman Chamomile’s effects on newborns has not been studied, it is best to consider it unsafe for nursing mothers to use.
Roman Chamomile Essential Oil has powerful sedative properties and should not be applied or diffused if you plan to drive, operate machinery, or perform a task that requires your full, complete concentration.
Although Roman Chamomile is good for relieving nausea, too much of it will actually make you more nauseous.
If you have an allergy to ragweed, marigolds, daisies, or similar plants, avoid Roman Chamomile and German Chamomile.
Sweet Marjoram
Sweet Marjoram Essential Oil (much like its cousin, Oregano Essential Oil) has a calming effect on your body, and the smell is lovely...just kind of “foody” by itself.
If you’ve eaten Mediterranean cuisine before or ever taken a good whiff of a gyro, Marjoram is one of the main spices you’ll smell. It has a very strong “seasoning” scent, but pairs well with a lot of gentler fragrances.
Pros:
It’s good for your circulatory system! Sweet Marjoram Essential Oil can increase your blood flow and lower blood pressure.
It’s good for aches and pains, especially on overused and exhausted muscles. This is my go-to massage oil after a workout. It’s also great for flu and fibromyalgia pain, sore muscle strain, and a queasy stomach. I originally bought it for menstrual cramps, but it’s worked best on my overexerted muscles.
Cons:
If you’re pregnant or breast-feeding, don’t use Sweet Marjoram Essential Oil and stick to only using marjoram in food amounts. This is also true for young children, as Marjoram Essential Oil isn’t a kid-friendly oil. Do not use this bath bomb for anyone under the age of 10.
If you have any of the below health concerns, I recommend talking to your doctor before using Sweet Marjoram Essential Oil in any capacity:
Bleeding disorders
Diabetes
Gastrointestinal or urinary tract obstructions
Lung conditions such as asthma
Ulcers
Slow heart rate or low blood pressure
Seizures or epilepsy
Juniper Berry
If you’re a weirdo like me and love the way a gin and tonic smells, you’ll fall in love with Juniper Berry Essential Oil the first time you sniff it. It’s got that cool, crisp, biting aroma along with a slight medicinal after-scent...all in a good way.
I love blending it with Grapefruit, Balsam Fir, Pine, Cedarwood, Camphor, or anything in the mint family. But Saturnalia is a special blend: truly therapeutic and relaxing. I can’t think of what could possibly be more relaxing than a Gin and Tonic...aside from a Basil Flower Gimlet--which also has gin!
Pros:
It’s a helpful digestive aid! Diffuse Juniper Berry for half an hour to an hour. The antispasmodic, tonic, and stomachic properties of this oil can help put that fussy tummy back into working order. Your twisted guts will unravel, you’ll build up more gastric juices, and be able to push whatever made you feel miserable out a little bit faster. Some people even use this oil to get some relief from constipation.
Carrying some extra water weight? Maybe Juniper Berry can help! I’m not gonna lie. I use it for this exact same reason, though I pair it with my Cardamom oil for a workout. I tend to bloat when I eat salty foods or my time of the month arrives. This flushes all that excess water right out! Juniper Berry makes your body sweat more, but also stimulates your kidneys. Just be sure to drink a lot of water if you use it for this purpose!
It’s good for arthritis, spasms, and cramps! Try a 1-3% dilution of Juniper Berry Essential Oil with a carrier (like jojoba, coconut, or sweet almond oil) and rub it into the sore area. It works quickly and should leave you feeling at least a little better in a few minutes.
It’s good for your skin and promotes a pretty complexion! Some people will use a 1-3% dilution ratio to treat eczema and psoriasis trouble spots. Try mixing it with jojoba oil (a carrier) for maximum effect. I’ll a drop of this (and Palmarosa Essential Oil) to my nightly astringent. I only get a zit or two during my cycle and that’s it.
Calm down, get a good night’s sleep, and banish all those stressful thoughts! Dilute the oil and apply it to the back of your neck or chest right before going to bed. I like to add a drop to my lotion and massage my temples after work, especially if it’s one of those days where I’m stuck in back to back development meetings and I think my head’s going to explode. Even a few drops in your bathtub should do the trick!
Cons:
Never apply this essential oil neat (undiluted) on the skin. Some people have reported irritation, redness, swelling, and a burning sensation when applied neat.
Prolonged use of this essential oil may result in kidney problems, seizures, and other severe side effects. Occasional use should be fine.
Juniper Berry is not an oil you should use if you are pregnant or trying to become pregnant. Juniper is a known abortifacent and can interfere with a uterus’s fertility.
If you are diabetic, you may want to avoid Juniper Berry Essential Oil. There have been reports of this oil lowering people’s blood sugar to unsafe levels.
Never take this oil internally, as it may irritate your gastrointestinal tract.
If you are on any blood pressure medications, contact your physician before using this essential oil in any large capacity, as Juniper Berry Essential Oil may make blood pressure harder to control.
Juniper Berry Essential Oil may make it more difficult to control your blood sugar before and after surgery. If you’re scheduled for surgery, ere on the side of caution and don’t use this essential oil (and therefore the Saturnalia bath bomb) at least 2 weeks before the scheduled surgery.
Juniper Berry Essential Oil is not a kid-safe oil. Don’t use this oil (or bath bomb) with any kid under the age of 10.
Blue Tansy
Ah…one of my favorite Essential Oils!
Blue Tansy comes from (believe it or not) a yellow flower. It gets its name because its oil is a dark navy blue. It’s a seasonal plant and one of my more expensive oils (about $60 USD for a 10ml bottle), but definitely one I plan to replenish once I run out.
The smell is reminiscent of German Chamomile, but so much stronger. I call it “Chamomile on Steroids” and is a very useful, versatile oil. It’s a cousin to the daisy flower.
Pros:
Treat fungal infections on your scalp, hair, nail, and skin! Blue Tansy has an antimicrobial and antifungal property. While you can apply it to bruised skin (safely diluted with a carrier oil), it’s never a good idea to put an essential oil neat (undiluted) on a cut, scrape, or wound. Still, if you’re prone to fungal infections, Blue Tansy may be your new best friend!
Treat seasonal allergies (without the grogginess)! Blue Tansy can be diffused to reduce seasonal or other allergies, as it is an asthma-safe oil. It has natural antihistamine properties, but isn’t a sedative. It’s cleared me right up and I’ve had wonderful results with this oil.
Fight aches and pains! Blue Tansy can be massaged into the muscles with a carrier oil to fight tired muscles after a strenuous workout or even the effects of rheumatism or gout. This oil has remarkable anti-inflammatory properties and can dramatically reduce swelling. I’ve even been able to kill a headache with this super-oil before.
Calm your jittery nerves! While Blue Tansy isn’t a sedative oil (like Roman Chamomile), it does have several calming properties. It promotes peace of mind, relaxation, and a more easygoing atmosphere.
Alleviate gastrointestinal discomfort! When applied (with a carrier oil) to the abdomen, Blue Tansy can help you with stomachaches, constipation, abdominal gas, and even menstrual cramps.
Get the perfect skin you always wanted! So long as it’s diluted first, Blue Tansy can be applied to the skin to moisturize the skin as well as kill many of the bacteria and fungi responsible for acne outbreaks.
Cons:
If you plan to purchase this oil, be sure you’re buying Blue Tansy Essential Oil, as opposed to Tansy Essential Oil. Tansy (not Blue Tansy) has a high concentration of the chemical thujone in it. Thujone is a dangerous neurotoxin and will really, really, REALLY mess you up.
Due to Blue Tansy Essential Oil’s high camphor content, people with Parkinson’s or epilepsy should avoid this oil. This also means it is absolutely NOT safe to diffuse around a cat or dog.
There are a whole slew of fake Blue Tansy Essential Oils on the market, so be sure you buy this one from a reputable source. I recommend Plant Therapy.
If you are allergic to daisies, avoid this essential oil.
Blue Tansy Essential Oil should not be used neat (undiluted on the skin) or ingested. Never ingest essential oils without first contacting your physician.
While Blue Tansy Essential Oil is considered safe for use during pregnancy, consult your doctor beforehand just to be on the safe side.
Exercise caution if you are using certain medications (antibiotics, antihistamines, antipsychotics, and antidepressants), as Blue Tansy Essential Oil may interfere with these medications.
Blue Cypress
There are multiple Cypress Essential Oils on the market (I have 3 in my collection), but Blue Cypress is my favorite. Alone, it is faintly woodsy and you have to use a lot of it to get its smell, but it makes up for its delicate smell by providing a whole slew of therapeutic benefits.
Pros:
Quickly heal cuts and scrapes! If you’ve scratched yourself, popped a pimple, or damaged your skin in any other capacity, you may want to consider adding a drop of Blue Cypress Essential Oil to your lotion or astringent. For some people, it’s been known to speed up the healing process. The oil contains an antimicrobial chemical (camphene) that helps keep some strains of bacteria and fungi from infecting a wound.
Cramping up or have a pulled muscle? Blue Cypress can help! This essential oil has antispasmodic properties, meaning it can help your muscles relax and ease up, even when all they want to do is seize tightly and make your life difficult. I’m not a physician, nor do I claim to be one, but studies have been conducted to determine Blue Cypress’s effectiveness on conditions like Restless Leg Syndrome and Carpal Tunnel. The results look promising.
Soothe aches and pains. Most aches and pains are caused by a buildup of lactic acid. Due to Blue Cypress’s diuretic properties, it can help your body flush that acid out faster, leaving you feeling better much, much sooner. Some people claim the diuretic effects of this oil can also help flush out several toxins.
This is an asthma-safe oil and can soothe a sore respiratory tract. You can breathe easy with a little Blue Cypress in your diffuser!
This oil promotes blood clotting. Another reason people like to use Blue Cypress on scratches and cuts is because it speeds up the clotting process. Blood vessels contract, blood flows more easily, and tissues can tighten up.
It’s a natural deodorizer! Although Blue Cypress doesn’t have a strong smell, it’s really good at neutralizing other odors. Try adding a few drops to your laundry detergent!
Had a stressful day? Calm down with Blue Cypress! Blue Cypress has sedative properties, which can make it easier for you to fall asleep after a long and trying day. As little as 5 drops in your bathtub can make all the difference.
Cons:
Due to the sedative properties of this oil, do not diffuse or apply this oil if you intend to drive or operate heavy machinery. It’s also ill-advised to diffuse this oil at work if your job requires your full concentration and alertness.
Since Blue Cypress promotes blood clotting, exercise caution if you are using a blood thinner or a clotting medication, as contraindications may occur.
Do not use this oil if you have an allergy to cypress or peaches. If you are allergic to a plant, I can guarantee you that you’ll be allergic to its essential oil.
Prolonged use of this essential oil may result in some kidney irritation.
There is not enough information available online to determine whether or not this oil is safe for breastfeeding or pregnant persons. Ere on the side of caution if you are nursing, pregnant, or intend to become pregnant.
#Saturn#Commander Saturn#Team Galactic#Galactic Bombs#Saturnalia#Professor Palmarosa#professorpalmarosa#Skye makes bath bombs
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What Should You Not Feed Squirrels?
Regulating Squirrels
Do squirrels carry disease?
What does it mean if a squirrel keeps staring at you? - Quora. The squirrel is tame (unafraid around humans). The squirrel is trying to obtain information about you, probably one of these. The hope is that the squirrel will chase you.
The Indian giant squirrel is the globe's largest recognized squirrel. It grows to 36 inches (1 meter) lengthy and Lansing wildlife removal evaluates up to 4 pounds (1.8 kilos). Squirrels are nimble, bushy-tailed rodents located all over the world. They come from the Sciuridae family, that includes prairie chipmunks, pet dogs as well as marmots.
Secure Plant Kingdom And Residential Property From Squirrels
What happens if a squirrel bites you?
Baby squirrels Babies are called kits or kittens and are born blind. They depend on their mothers for around two or three months.
Return in a day or 2 and also you'll likely locate that you've captured the squirrel( s) or omitted them. You'll recognize that you have actually resolved your squirrel issue if you no much longer listen to scooting noises up above in the attic. Secure them shut with steel mesh as soon as you have actually discovered all of the attic's entry holes.
Can I kill squirrels in my yard?
Diseases Squirrels Carry Squirrels are known to carry numerous diseases, though only a few are dangerous to humans. Some of the more common include tularemia, typhus, plague, and ringworm. While all mammals are capable of getting rabies, squirrels are very rarely rabid.
Heaps of big rocks as well as brush cover bring in serpents that treat on squirrels as well as gophers. When they stand at attention, ground squirrels-- Ground squirrels have long fuzzy tails that curl up. They have round, plump bodies and choose to consume fruits, acorns or tree nuts, plant leaves, as well as various other eye-catching plant that expands over ground. In your lawn, they can develop large, easy-to-see openings that result in a network of burrows in a colony.
They are energetic throughout the day and also eat nuts, seeds, conifer cones, however will likewise eat fruits, birds' eggs, as well as nestling birds. They will defend their regions more so than other squirrels.
Their http://www.usnetads.com paws are precise as well as so sharp that they are usually utilized to come down trees head-first.
I do not recognize exactly how else you will get them out of the house.
To lure a vermin trap, make use of the food that the four-legged bug appreciates, such as fruit for ground squirrels and alfalfa or hay for sly gophers.
The individual that traps them needs an authorization from the New York State Division of Environmental Conservation.
You can find wild animals control operators (individuals with permits to trap them) with this web page.
Hello there Barbara, if you have squirrels harming your home, they would be thought about a nuisance pet.
What does it mean when a squirrel stares at you?
It is very rare for a squirrel to transmit rabies to a human, but it is worth mentioning due to the dangers of being exposed. If bitten by a rabid animal, initial symptoms include fever, headaches, and weakness. If left untreated, symptoms can progress to insomnia, confusion, paralysis, and eventually death.
Instead, these are fish-flavored nuggets that have a vast broadcasting array, indicating they can draw in squirrels from really far. The Ramik diphacinone-based rodenticide is available in the kind of half-inch nuggets.
What are squirrel babies called?
Marmots, called woodchucks or groundhogs in the U.S., are much larger than their squirrel cousins. Marmots average about 2 feet long.
There are less squirrels to breed, as well as those that do produce less and smaller litters. Each female in the trash can generate one trash of young, occasionally 2, during her initial year and two trashes during yearly afterwards. For that reason, squirrel numbers https://ezlocal.com/mi/northville/pest-control/0916290277 can promptly escalate when food supplies are great. Gray squirrels and also fox squirrels occur throughout much of the UNITED STATE
The strength versus durable squirrels and rats is impressive as well as in my point of view worth the premium cost. An additional Bell special is the Bell Final Blocks Rodenticide. These lure chunks were established to attend to larger rats such as grown-up squirrels. The lures are larger, longer, and have superior moisture resistance in addition to good mold resistance.
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Because their numbers far exceed the number of killers, squirrels are plentiful in the wild. The large populace as well as decreasing all-natural habitat as a result of construction in several areas create them to seek sanctuary in houses. The freezing months of autumn as well as winter season create squirrels to look for the heat that is located in attics.
My squirrels like yellow squash, broccoli, grapes, watermelon, carrots, cantelope, peas as well as apples. We go easy on the fruit, because many of them will obstruct calcium absorption. Yet, a bit each day "rounds-out" their nutritional needs. If you take pleasure in feeding squirrels whether in your yard or the general public, make sure you do not feed them any sweet of any kind of type, particularly delicious chocolate.
The gray squirrel is one of the most typical structure-infesting squirrel species. Individuals food is not good for wild animals consisting of squirrels. These have little or no dietary value to the wildlife and also can result in lack of nutrition, conditions and also defects. If you enjoy pets however it is not always the best idea, Feeding squirrels might come normally.
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New from Kiehl's Powerful-Strength Line Reducing & Dark Circle Diminishing Vitamin C Eye Serum . . . 🌱 Tri-peptides,improves uneven texture and the look of fine lines and also helps reverse a dehydrated appearance. 🍊Vitamin C-lightens, brighten, tightens the skin, fantastic ingredient for skincare and a great strength to see visible results quickly! 💧Hyaluronic Acid-holds 3x times its weight in water,making it great for moisture retention and wrinkle reduction . . . Social distancing and staying at home hasn't been exactly kind to my skin. My skin has been so dry and sensitive lately, especially around my eyes, and yes my dark circles are now a permanent guest on my face thanks of too much screen time, insomnia and hay fever 🙈 So, easy to understand that now more than ever I am on the hunt for good eye products! And im happy to report Kiehl's did not disappoint me with this one!It promises to deliver powerful results with fine line reducing and dark pigmentation dimenishing and it indeed improved so much my under eye area in terms of hydration and fine line reduction and I did notice I looked more awake each morning. . . . 10/10 would recommend . . . #selfcare #kiehlsbel #kiehlsnl https://www.instagram.com/p/B_7gTMjgAJC/?igshid=1k33mofvpz7e5
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ReliSlim Original
You can find so many dietary supplements and pills to boost weight loss and ReliSlim Original is yet another option you can try in this regard. Made by Loock Pharmaceuticals, it is supposed to work by suppressing your appetite. It is not really a dietary supplement because you can get it only after your doctor’s prescription, and that is mainly because its main ingredient is pseudoephedrine, a stimulant usually found in OTC decongestants. It helps reduce your appetite, so you could follow you diet plan more effectively and lose weight in return.
Made by a South African company called Look Pharmaceuticals, ReliSlim Original provides you with d-Norpseudoephedrine HCL to helps suppress your appetite and make it easier to stick to your low-calorie diet. The idea looks good, but the question is, “Should you really be trying something that includes a banned ingredient?” Is it really effective?” Here is our review to help you decide.
ReliSlim Original Pros
May help reduce appetite
Sometimes effective for women
Does not contain additives
ReliSlim Original Cons
No complete list of ingredients
Rarely effective in men
Expensive
Causes several side effects
Not a proper fat burner
Watchdog Rejected Diet Pills
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What You Need To Know About ReliSlim Original
ReliSlim Original is supposed to work better as compared to its sibling, ReliSlim Herbal, which provides you with some natural ingredients, like green tea extract, caffeine, and more. It contains pseudoephedrine, which is supposed suppress appetite and increase fat oxidation in the body. It is a schedule-6 medicine, so you cannot get it without a script. To get good results, you still need to follow a good diet plan and stick to a suitable exercise program.
What Are The Side Effects Of ReliSlim Original?
ReliSlim Original can cause several side effects, even when taken as direction, and that is mainly due to pseudoephedrine. Some of the most common side effects are insomnia, headache, nausea, and nervousness. You may also experience increased heartbeat and elevated blood pressure. Check out “Side Effects” section for further details.
How Much Does ReliSlim Original Cost?
You will end up spending £95 to get one bottle of ReliSlim Original. You can get 30 tablets or 90 tablets per bottle.
Our Verdict On ReliSlim Original
ReliSlim Original is supposed to work because it contains pseudoephedrine. It is true that pseudoephedrine is quite like its chemical relative ephedrine when it comes to stimulating central nervous system and suppressing appetite as a result. It works by narrowing blood vessels and increasing your heart rate. It is supposed to burn fat when your heart rate and blood pressure is up, but that is certainly not a highly recommended way to lower weight. Moreover, appetite suppressants can only serve as a short-term weight loss solution and lose their effectiveness over time; in fact, many people say that their appetite comes back strongly once they stop taking ReliSlim Original. You require a doctor’s prescription to get it, which can be an issue, and it costs you some good money (£95). So, avoid it and look for a weight loss supplement with true fat burners and scientifically proven ingredients.
The most popular consumer choice in 2017 is Phentaslim.
With a combination of proven ingredients, superb customer service and a 60-day money-back guarantee, Phentaslim is making big waves in the diet world.
Find out why thousands of people are choosing Phentaslim to achieve their weight loss goals, and why it's also the editor's top selection.
Read the Watchdog Phentaslim review here.
Key Features
Ingredients
Side Effects
Testimonials
Guarantee
Where to Buy
ReliSlim Original Review
ReliSlim Original is designed for people struggling to deal with obesity. This weight loss pill contains d-Norpseudoephedrine HCL, which is a chemical version of ephedrine or ephedra. Though banned in many countries, pseudoephedrine is supposed to work by suppressing your appetite. It is essentially an appetite suppressants and does nothing to boost your metabolism or burn fat directly. Should you really be putting your money on ReliSlim Original that relies only on pseudoephedrine to produce results? Let’s find out.
ReliSlim Original Facts
Appetite suppressant
30 tablets and 90 tablets
ReliSlim Original contains pseudoephedrine, which is a purified form of ephedra, an herb widely used in Traditional Chinese Medicine. Some studies show that ephedra may help treat bronchitis, asthma, and hay fever, and relieve symptoms of flu and cold, including cough, nasal congestion, chills, fever, and cough. Many OTC remedies now include synthetic ephedrine compounds, such as pseudoephedrine. You can also find this ingredient in weight loss supplements, such as ReliSlim Original, but it is important to understand that the information regarding the effectiveness of pseudoephedrine for energy, weight loss, or athletic performance is controversial and inconclusive. In fact, the FDA has banned dietary supplements that may contain ephedrine, ephedra, ma huang, norephedrine, pinelllia, or Sida cordifolia.
It is a fact that pseudoephedrine is not as potent as ephedrine, but it can still affect your central nervous system. As it is a stimulant, you may notice some effects in the beginning, but you may develop a tolerance against it, which makes it less effective over time. Moreover, there is not enough scientific evidence to confirm that regular intake of pseudoephedrine can help suppress appetite and trigger fat loss. Some studies show that ephedrine does not work when used without caffeine. For example:
For example, in a double-blind, placebo-controlled trial, 180 overweight individuals were placed on a weight-loss diet and given either ephedrine/caffeine (20 mg/200 mg), ephedrine alone (20 mg), caffeine alone (200 mg), or placebo, 3 times daily for 24 weeks. The results showed that the ephedrine/caffeine treatment significantly enhanced weight loss, resulting in a loss of more than 36 pounds as compared to only 29 pounds in the placebo group, a 7-pound difference. Neither ephedrine nor caffeine alone produced any benefit.
It is worth mentioning that even if pseudoephedrine offers some benefits, you may not get any from ReliSlim Original mainly because it does not provide you with enough of this stimulant in the first place. You get 20mg of pseudoephedrine from each tablet of ReliSlim, but many studies have found that you should start with at least 120mg of pseudoephedrine to get any results.
The company states that ReliSlim Original helps lower the levels of cortisol, but studies show that the purified versions of ephedra (pseudoephedrine and ephedrine) works by raising cortisol levels. You feel less hungry when your cortisol levels are up, but taking ephedra-based weight-loss supplements would lead to chronically high cortisol levels, which is going to cause several complications. You may actually experience severe consequences if you do not pay attention to maintaining a balanced diet at the same time.
How to Take ReliSlim Original
Each tablet of ReliSlim contains 20mg of pseudoephedrine. You should talk to your doctor before using ReliSlim. However, here is what the official site states in terms of use:
Take one capsule with a full glass of water, three times per day: morning, mid day and early evening. You may take ReliSlim with or without food. Do not exceed 3 capsules per day.
Even if ReliSlim works to suppress appetite, it is not going to make any significant change in your weight in a short time. By suppressing your appetite, you may be able to follow a low-calorie diet more efficiently, but you are going to see results if you limit your caloric intake for long enough. That may not be a great idea though, as using ReliSlim Original for long can lead to several side effects, mainly due to its pseudoephedrine content.
ReliSlim Original Concerns:
Proprietary blend
Several side effects
No money-back guarantee
Very expensive
Another issue is that even if you continue to use it for a while and end up losing weight by eating less, you may not be able to maintain that weight. Supplement manufacturers state that apptite suppressants help you feel less hungry, so you can consume less simple carbs, less fat, and fewer calories. Overtime, it will become a habit, and you will continue to eat less even after eliminating the appetite suppressant. That does not happen in the real world though. Many customer reviews have mentioned that your appetite returns strongly once you have stopped taking ReliSlim Original, and that means you may put on all the weight back along with some more after you discontinue the use of these weight loss pills.
It is also important to keep in mind that you are not going to get any results just by suppressing your appetite. You need to pay special attention to following a balanced diet and sticking to a good exercise program. You may not feel hungry after you start taking ReliSlim Original, and if you do not know what to eat, you will end up experience several health complications because your body would not be getting enough nutrients. Cutting calories is certainly helpful, but that can be dangerous if you also cut the amount of essential nutrients that your body need to function properly. Therefore, ReliSlim Original is never a good choice for anyone not already aware of how to follow a healthy diet plan.
The side effects associated with the use of pseudoephedrine make it difficult to use it on a long term basis. Considering the customer reviews, it becomes clear that increase heartbeat and headaches are some of the most common side effects associated with ReliSlim Original. Not everyone is going to experience these effects, but many people just cannot tolerate ephedrine in this form and end up experience side effects. The company suggests that you should drink plenty of water while taking ReliSlim Original or else you may end up dealing with a dry mouth or dry mucus membranes. It can also interfere with your sleep if you take it late in the day.
Even if you assume that ReliSlim Original reduces your appetite and helps lower your caloric intake, it is never a good idea to spend so much money just to get an appetite suppressant. You have to pay £95 to get ReliSlim Original, but you can easily get other appetite suppressants with scientifically proven fat burners and appetite suppressants at a much lower price. You can save that money as well and spend more time in the gym and follow a healthy diet plan to lose weight in a healthy way without having to worry about any side effects, which are usually associated with products like ReliSlim Original.
What Does ReliSlim Original Claim To Do?
ReliSlim Original is a weight loss tablet that works by suppressing appetite. You can get good results only when you combine it with a healthy diet plan and appropriate exercise program. Here are some of the claimed benefits of ReliSlim Original
It helps suppress your appetite to prevent overeating.
It helps lower stress in a short time.
It helps improve your mood.
It helps get rid of abdominal fat.
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It helps lose weight in a short time.
Does ReliSlim Original Work?
It may work for some people, especially in the beginning, but it can lead to some serious side effects over time. ReliSlim Original contains pseudoephedrine, a substance banned in many countries. It works by suppressing your appetite, but unfortunately, appetite suppressants work for a short time only and your appetite is likely to come back strongly once you stop taking them. The same is the case with ReliSlim Original. There is also no reliable scientific data to confirm that taking as little pseudoephedrine as found in ReliSlim can lead to a significant reduction in your weight. Therefore, we believe that you will be better off trying a weight loss supplement with some natural fat burners, such as caffeine, green tea extract, yohimbe, carnitine, ALA, etc., to help burn fat efficiently.
What Are The Ingredients of ReliSlim Original?
There is not enough information about the ingredients found in ReliSlim Original, but the main active ingredient is D-Norpseudoephedrine HCL.
Pseudoephedrine is a synthetic form of ephedrine and is a sympathominetic compound that my help suppress appetite. It may aid in weight reduction when you use it in combination with a low-calorie diet and exercise program. The stimulant actually works by affecting hypothalamic appetite centers in your brain – the use of anorectic agents helps manipulate the system. ephedrine, pseudoephedrine, and phenylpropanolamine increase the concentrations of norepinephrine adrenergic neurotransmitter, which may result in decreased food intake.
Unfortunately, there is no reliable scientific research to confirm that pseudoephedrine can suppress appetite to an extent that it results in weight loss. Moreover, there may be certain side effects associated with the use of pseudoephedrine and any ephedra-based weight loss supplement.
Does ReliSlim Original Have Any Side Effects?
ReliSlim Original works by suppressing appetite, but it contains pseudoephedrine, which is banned in many countries because of certain side effects.
You may end up experiencing serious consequences when you take pseudoephedrine on a long-term basis. The effects can be serious when you combine it with caffeine. The combination is not safe for individuals with heart disease – it can also affect people with no existing heart conditions. You should be very careful when taking ephedra-based weight loss supplements, as they are associated with inflammation of the liver and the heart. It can actually trigger an autoimmune reaction and lead to serious problems.
As it serves as a stimulant, it can produce side effects such as anxiety, restlessness, irritability, nausea, headaches, and vomiting. Pseudoephedrine may sometimes lead to urinary problems. Other serious side effects include rapid heartbeat, high blood pressure, seizures, stroke, and even death.
It is important to avoid ReliSlim if you have cardiovascular disease, such as high cholesterol, hypertension, angina, intermittent claudication, or abnormalities of heart rhythm. People with hepatitis, diabetes, glaucoma, vasculitis, hyperthyroidism, and diseases of the nervous system should also avoid it.
Caution: Not suitable for individuals under 18 years of age. If you are pregnant or breastfeeding consult a doctor before using this product. If you are taking any medication, or have any type of medical issue, consult with a doctor before using this product.
Are There Any Customer Reviews For ReliSlim Original?
You cannot find many customer reviews for ReliSlim Original, but whatever we could find was not impressive either. For instance:
I have been using it for a few weeks but it seems to have no effect on my weight.
I stopped using it after a few days because it gave me some serious headaches with nausea.
How long does ReliSlim take to work? It’s been six weeks and no results yet!
I do not think it really works, and it is very expensive too.
Does ReliSlim Original Offer a Money-Back Guarantee?
No, it does not come with a money-back guarantee, which may serve as a deal-breaker for many.
Where Can I Buy ReliSlim Original?
ReliSlim Original is manufactured by a South African company but is shipped anywhere in the UK. Several third-party retailers also stock ReliSlim.
The post ReliSlim Original appeared first on Diet Pills Watchdog.
http://ift.tt/20dXvcA
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A question and a prompt for you! Have you noticed that Gladio's always sneezing, even if you dress him up in the shirt + jacket casual outfit, and do you think there's any deeper interpretation to be had from that character animation? As for the prompt, the first time Noct encounters (or gets hit by) the stasis-inducing attacks of the MTs, how would you write him and the bros handling it? Lastly, thank you so much for writing RDD, it's one of the few things giving me life these days.
Yes! I’ve noticed his sneezing habit! And it cracks me up, tbh. Especially when he does it after calling Prompto a wuss. I know in Japan sneezing is usually supposed to mean that someone is talking about you (someone must be talking about Gladio a LOT) and I wonder if that’s why it’s there? Personally, I think it’s great that here’s this big badass dude who loves camping and woods and probably anything involving the word ‘hewn,’ and he is laid low by hay fever on the regular. Seriously. Someone put that man on some Nasacort.
PS: You are very welcome
(Those are the harpoon attacks, right? That put him in Stasis? TBH it’s been so long since I’ve fought MTs as any kind of serious combat I don’t remember! These days I just blow ‘em up in a pack with one spell as soon as they fall out of the carrier. And then Noct laughs about it a lot. I’m not sure it’s healthy. But the guy’s level 102, what can you do?)
The first time it happened, he honestly thought he was dying. He’d pushed the limits of his energy before, in training or in some long combat, but always it was a gradual drain, and he knew the cause. Ignis was fond of telling him, “You’re only meant to do that so many times, Noct,” and Noct would wave it off with a grimace. Yeah. I overdid it. Time to limp behind a rock, take ten deep breaths, and wait for the hollow ringing in his ears to subside. Unpleasant, not unfamiliar. He knew how it came, what it was, and how it would pass.
Not this time. He was in mid-warp when he was struck by the MT’s attack and he fell from the sky like a hammer, landing in a heap at Ignis’ feet. The fall took the air from his lungs, and in the split-second as he tried to finish warping, tried to keep breathing, tried to sort out where he’d been hit and how bad it was bleeding and was he missing any limbs–he thought it was over. Over on some dusty hillside whose name he didn’t even know, over before it had even had a chance to begin.
“It’s not like training,” Gladio had warned him, before they left Insomnia. “You get in trouble, and whatever got you there ain’t gonna back off while you take a breather. Monsters don’t fight fair. MTs don’t wait for you to get back on your feet. They’ll gore you from behind and not give a damn. This is war, not a dance class. You can die out there.”
No. Not like this. It wasn’t possible. It was too stupid. But Noct couldn’t breathe. His vision was a rapidly collapsing tunnel of light, and very far away, through a buzz of pink noise, someone was shouting. Distant explosions, like depth charges, rocked him without reaching him. The last one was small, bright. Something glittered in his vision.
Then the Elixir Ignis broke in his hand hit Noct like a dozen doubleshot espressos, pulling his brain from stasis to stability with such speed that he was dizzy all over again.
“If I might suggest,” Ignis said, pulling Noct to his feet, “try not to let that happen again.”
“Don’t worry,” Noct said, sword bursting into solidity in his hand, magic propelling him towards the last magitek troopers left standing, his voice lingering like his own afterimage behind him. “Once was enough.”
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Hair Restoration Project | Dr William Clearfield Reno
Hair Restoration Project | Dr William Clearfield Reno
The Hair Restoration Project PRP technique can treat male and female pattern hair loss, alopecia areata, and eyebrow hypotrichosis
Below there is a lot about thinning hair in Reno…I mean a lot of information. More than you need but it is important that you have the option of knowing everything there is to know about male and female pattern baldness and hair loss treatments in Reno NV. This article is about understanding hair loss and how and why your thinning hair and baldness pattern can be replaced without surgery.
Contact Dr. William Clearfield at the Clearfield Medical Group to schedule your consultation to see if the Hair Restoration Project is right for your male or female pattern baldness. 1-775-359-1222 and go to your website www.drclearfield.net
More information on the “Hair Restoration Project” go to http://ift.tt/2yHJH3y
Who doesn’t admire a fine head of hair? We covet, envy, and even worship a great head of hair..My late great mother, (lung cancer, not from cigarettes, bad but too much casino air, Atlantic CIty, New Jersey) in hospice, on the day before she passed, woke from her morphine induced “sleep”, looked around at us sitting by her bedside, and asked, “How’s my hair?” Her final words. (True, story. To be fair, Mom was always a Jackie Kennedy, never Onassis, wannabe.) Millions aren’t so lucky. In the United States, by age 60, 65% of men, and 80% of women have noticeable hair loss. In total 56 million men and women experience hair loss.(2)
To understand hair loss and what can be done to correct it, we must understand the natural growth, and demise, of a single hair follicle. Hair growth takes place in four phases:(4)
1. ACTIVE GROWTH (ANAGEN) PHASE The active growth phase lasting two to six years. Hair grows 18 to 24 inches before entering into the transitional phase. 80-90% of all hair follicles are in this growth phase on a healthy head. 2. TRANSITIONAL (CATAGEN) PHASE The shortest of the hair cycles lasting one to two weeks occurs when the lower third of the hair follicle is cut off from its blood supply. The hair itself shrinks to 1/6 its expected length. Catagen hair accounts for 2-3% of all follicles at any one time. 3. RESTING PHASE (TELOGEN) PHASE The dormant stage lasting one to four months. 10-15% of all hairs are in the Telogen phase. Telogen hair sheds or is pushed out by new hair follicles as the cycle renews. Ideally only 10-15% of hairs are telogenic. When more than 20% of hair are in this “resting” phase, noticeable thinning occurs. 4. SHEDDING PHASE (EXOGEN) PHASE Hairs in this phase shed easily as the follicles are preparing to return to the Anagen phase.
Types of Hair Loss (5) 1. TELOGEN EFFLUVIUM An abnormally high percentage of hair in the Telogen phase results in an overall thinning of hair. Common causes of this type of hair loss include chronic stress, toxins, fungal infections, nutritional deficiencies, and hormonal imbalances. 2. ANDROGENETIC ALOPECIA “Male-pattern” baldness is not limited to men. In women, the hair thins at the crown or widens in the part. The hair thins revealing a bare scalp. 3. ALOPECIA AREATA Presents as patches of lost hair. Alopecia Areata is usually an autoimmun condition with an association of nail issues also. 4. MISCELLANEOUS TYPES a. Traction from braids, weaves or wigs b. Chemotherapy-Related Hair Loss c. Frontal Fibrosing Alopecia (FFA) d. Lichen Planopilaris (LPP) Etiology of Hair Loss (6) 1. Sub-Optimal Thyroid Function The thyroid is the body’s “gas pedal,” determining how fast, or slow all bodily functions operate. When slowed due to inadequate “fuel,” namely usable thyroid substrate, the oils, fluids and tissues, especially the hair follicles function inadequately. The hair follicles spend an abnormal amount of time, and hence an abnormal number of hair follicles are in the Telogen or resting phase, resulting in a form of Telogen Effluvium. 2. Nutritional Deficiencies Nutritional deficiencies, specifically silica and zinc leads to hair loss. Micronutrient testing is indicated when this is suspected. 3. Stress In 1881, George Miller Beard, M.D., a neurologist and graduate from the New York College of Physicians and Surgeons, described a condition based on excess “nervous energy.” Constant over stimulation of the nervous system from the fast paced American lifestyle resulted in “neurasthenia,” burnout, or nervous exhaustion.
Symptoms of neurasthenia included nervous dyspepsia, insomnia, hysteria, hypochondria, asthma, sick-headache, skin rashes, hay fever, premature baldness, inebriety, hot and cold flashes, nervous exhaustion, brain-collapse, and forms of ‘elementary insanity. The best educated and most sophisticated Americans were the most afflicted. Theodore Roosevelt and Frederic Remington were two prominent figures of their day suffering from “neurasthenia.”
The “cure” was a withdrawal from the modern life, rest and a less hectic lifestyle. Critics countered that urban life in the late nineteenth century had produced a “pathetic, pampered, physically and morally enfeebled 97 pound weaklings, unworthy successors to the stalwart Americans who had fought the Civil War and tamed a continent.”.(7)
Physicians pigeonholed patients into this “nervous energy” category, relieving themselves of more vigilant diagnosis. Early signs of tuberculosis, heart failure and epilepsy were chalked up to neurasthenia and when later discovered to be in error, gave fuel to those who saw this “malady,” as a sham. The term neurasthenia is no longer used to describe any medical condition, but the conditions that lead to its “discovery,” diagnosis and its’ symptoms are remarkably similar to a hormonal condition with distinct diagnostic criteria known as “Adrenal Fatigue.”
The adrenal glands, pea sized organs, sit on top of the kidneys. They produce hormones that regulate blood pressure, electrolytes balance, blood sugar, immune responses, digestion, and stress responses. In regards to the latter, constant unremitting stress, as experienced by nearly everyone in today’s society, hijacks normal hormonal responses, redeploying the adrenals’ resources, in the form of the hormone cortisol, to combat the “evil” of the moment. The other adrenal functions, digestion, immune response, and thyroid hormone production, are temporarily put on hold or slowed until the stress has passed.
Cortisol is our protector. It lies in wait, like the lineup of computer programs opened at startup and running in the background, ready at an instant, when needed, to spring into action. In an ideal world, the stressor passes quickly and the adrenals resume lurking behind the scene awaiting the next crisis. In our non-ideal world, one stress begets a second stress, which begets a third stress, ad infinitum, putting the adrenal gland into permanent overdrive. The body is flooded with cortisol driving the adrenals to handle the stress but eventually it cannot keep up. The result is adrenal “burnout” or fatigue.
The thyroid is exquisitely impacted by the constant flooding and eventual depletion of cortisol. High levels signal the brain to lower the production of stressor hormones. Unfortunately, thyroid hormone is produced in the same pathway and is unwittingly lowered. Recall the critical step of converting T4 to the usable thyroid hormone free T3. Stress hormones affect the enzymes that convert T4 to T3 converting T4 into an inert unusable reverse T3.
Chronically elevated cortisol levels release inflammatory cells which desensitizes thyroid receptors to thyroid hormone. Like diabetics who don’t respond to insulin, adequate thyroid hormone may exist, but the result is inadequate thyroid utilization.
Increased circulatory cortisol increases estrogen in the blood stream. Estrogen increases thyroid binding globulin, tying up T3 and T4, reducing hormone levels to achieve the conversion to free T3. Elevated cortisol levels with its’ inherent state of chronic inflammation can trigger “leaky gut syndrome,” latent infections leading and autoimmune diseases.
Hair follicles accumulate in the resting (Telogen) phase.
4. Sex Hormone Imbalances Male: Excess testosterone metabolizes into dihydrotestosterone (DHT) and estradiol. DHT attaches to hair follicles, effectively strangling them causing “organ” death. The key to preventing, slowing, or possibly reversing the effects of DHT is by inhibiting this conversion of Testosterone into DHT. (Essentially the mechanism of action of hair loss products such as Rogaine.)
Type 2 5alpha reductase is the enzyme that that converts testosterone into DHT. Type 2 5alpha reductase is primarily found in the hair follicles and the prostate gland.
The conversion of too much testosterone to DHT results in androgenetic alopecia. As a man ages he retains estrogen and converts testosterone into estrogen at a higher rate. The result is 1+1=4, the 4 being excess DHT as a result of excess estrogen.
Women: Estrogen dominance is the culprit in women. Child birth, birth control medications, stress, toxins, along with entrance into the perimenopausal arena, creates an estrogen dominant pattern. Estrogen signals the liver to produce inordinate amounts of Thyroid Binding Globulin (TBG). T4, the “storage unit” of the thyroid must convert to T3, the hormone that the “work.” Excess TBG leads to an inability to convert T4 to T3, resulting in a relative hypothyroidism and Telogen Effluvium. Estrogen dominance results in excess DHT, leading to a female version of “male pattern” baldness. (8) Miscellaneous areas to explore if estrogen dominance is ruled out: Heredity, insulin resistance, polycystic ovarian syndrome and a low antioxidant state. (9)
5. Medications Causing Hair Loss (10) Antibiotics: gentamicin, chloramphenicol Anticoagulants: warfarin, heparin Antidepressants: fluoxetine, desipramine, lithium Anticonvulsants: valproic acid, phenytoin, carbamazepine Cardiovascular meds: ACE inhibitors, beta blockers Chemotherapy drugs: doxorubicin, vincristine, etoposide Endocrine drugs: bromocriptine, clomiphene, danazol Gout medications: colchicine, allopurinol Lipid lowering drugs: gemfibrozil, fenofibrate, cholestyramine, clofibrate NSAIDS: ibuprofen, indomethacin, naproxen Reflux/ulcer medications: cimetidine, ranitidine, famotidine Antithyroid drugs: iodine, PTU Retinoids: vitamin A overdose, isotretinoin 6. Trichotillomania- Repetitive hair pulling resulting in hair loss. Considered an OCD variant. Treatment usually includes behavioral therapies, SSRI’s or other drugs to treat OCD. Metabolic therapies include NAC, inositol, L-tryptophan, niacin and vitamin B6.
7. Scarring Alopecia- Resulting from burns, radiation, or other injuries or diseases. Destroys the dermis with permanent hair loss. Rx: Vitamin A 150,000 IU qd for 6 weeks stopped disease progression. Maintenance Rx: 150,000 IU qd for three 6 week periods every year. (11)
Conventional Therapies for Hair Loss (12)
Cyproterone acetate Minoxidil Flutamide Ketoconazole Finasteride Hair Transplantation Dutasteride Light Therapy, Botulinum Toxins Holistic Resolutions to Hair Loss
1. Proper Hypothyroidism Diagnosis & Treatment (13-14)
The thyroid functions as the body’s “gas pedal.” Like Goldilocks, we need it to be just right, not too little, not too much. The gland produces two major hormones, triiodothyronine (T3), the active hormone, and thyroxine (T4), the storage hormone. The thyroid also produces calcitonin, a hormone responsible for calcium balance and bone density and magnesium.
98% of all thyroid disorders results in hypothyroidism. Common symptoms include cold intolerance, unexplained weight gain, fatigue, thinning of the hair, the outer third of the eyebrow, the skin and the nails, increased body fat, energy loss, cognitive loss, memory loss, mood disorders, lowered body temperature (never greater than 97.6 F), fluid retention, and a poor sense of well-being.
When the underlying cause of hypothyroidism is the immune system, not the thyroid per se., and it is not addressed, the treatment will not be effective. 25 percent of patients with autoimmune, Hashimoto’s thyroiditis develop polyglandular syndromes (such as pernicious anemia, diabetes, or adrenal insufficiency) or other autoimmune diseases (such as Sjogren’s syndrome).
2. Key Supplements for Healthy Hair (15)
Biotin- Water-soluble B-vitamin found in green leafy vegetables. Regulates mitochondrial enzymes in hair follicles. Depleted by cigarette smoking, aging, excess alcohol, strenuous exercise, burn victims, shortened gut syndrome (GI resections), achlorhydria, and raw egg consumption. (16-17) Use orally or in essential oil mixture. Dose is 30-100 mcg/day.
Zinc -Promotes cell reproduction, tissue growth and repair of broken tissues. Maintains the oil-secreting glands attached to hair follicles. Study showed that 15 patients with alopecia areata received 45 mg of zinc TID. All had complete return of hair growth within 6 months. (18) Maintenance dose is 15 mg per day along with 1 mg copper as a balance.
N-Acetyl-Cysteine- Precursor to glutathione the most powerful antioxidant in the body. Protects DNA from chemical damage, detoxifies heavy metals, and it keeps arteries and airways open. It activates important functions of the immune system.
B Vitamins (B6, B12)- In the form of Pyridoxal 5-Phosphate (PLP), the B Vitamins act as catalysts to activate the enzymes and chemical reactions to commence the metabolism of keratin and melanin in the hair follicles. B vitamins control hormone release., regulating androgen interaction with hair metabolism. Testosterone breaks down into dihydrotestosterone (DHT). Elevated DHT levels diminishes hair growth by decreasing the length of the anagen, hair growth phase, and the follicle size. Vitamin B6 binds to the testosterone receptors, stopping DHT formation.
Niacin- Vitamin B3 converts carbohydrates into energy, delivers the energy to cells where needed and maintains cell integrity. Niacin is a vasodilator, hence the niacin “flush” so common when taken, “washes” carbohydrates through the body, reducing visceral fat and serum cholesterol. The flush can be minimized by taking niacin with a meal or starting (with a) low dose and gradually increasing its potency. The vasodilator effect of niacin delivers increased oxygen and nutrients to the hair follicle resulting in thicker hair.
Arginine- L-arginine, a precursor to nitrogen oxide, opens the potassium channels of the cell, improving blood supply to the hair root.
Lysine- An essential amino acid, lysine stimulates collagen and is necessary for restoring damaged hair. Food sources for lysine include fish (especially salmon, sardines and cod), dairy, poultry, red meat, pork, legumes, nuts, spirulina and pulses.
Saw Palmetto (for Men)- Prevents conversion of testosterone to DHT
Acetyl-L-Carnitine- Up regulates proliferation and down regulates apoptosis in hair follicle keratinocytes. Turns fat into energy. Acetyl-L Carnitine improves the membrane potential of the hair follicle which is significantly diminished along with potassium channel function within withering hair follicles.
Iron- A lack of iron results in a decrease in hemoglobin, the ingredient that carries oxygen for growth and repair of all cells including hair follicles. Iron deficiency states move hair follicles into a premature and prolonged telogen (resting) phase. Hair growth is a “non-essential” bodily function. It is one of the first systems to shut down in a state of iron deficiency. Hence, hair loss is an early warning sign of iron deficiency anemia.
Vitamin D- Essential for calcium homeostasis, immune regulation and cell growth. A host of autoimmune diseases, including alopecia areata, exhibit low levels of Vitamin D. The severity of serum 25(OH)D deficiency is inversely related to the severity of hair loss.
Gluten- Hair loss is an early sign of gluten intolerance. In all cases of alopecia or extensive hair loss, we recommend a strict gluten free diet for 4 weeks as a trial. (19)
Vitamin A- Hair loss is a symptom of Vitamin A toxicity especially in renal failure. Usually resolves when toxicity is addressed. (20)
Emu Oil- Contains linolenic acid a potent 5-alpha reductase inhibitor. Compound with virgin coconut oil to create an antibacterial, anti-inflammatory scalp treatment to DHT.
3. Adequate Protein Insufficient protein effects on your hair growth. The CDC recommends 46 to 56 grams of protein per tain to maintain hair growth. (21) Inadequate protein results in protein rationing by shutting down less important functions.
4. Iron When iron levels fall below 30 mg/L hair growth and regeneration are decreased. Iron deficiency commonly causes hair to be brittle and dry with narrowing or splitting of the hair shaft. Iron replacement restored hair growth in those whose sole issue was iron deficiency. (22-23)
5. GI Evaluation-The 4 R’s Depleted stomach acid leads to impaired protein digestion and decreased nutrient absorption. Disturbed GI flora leads to inadequate nutrient utilization. Pancreatic enzyme deficiency leads to malabsorption of essential fatty acids and zinc.
The “4 R’s” include: (24)
“Remove” inflammatory foods such as gluten, dairy, corn, soy, eggs and sugar. Eliminate gastric irritants like alcohol, caffeine or drugs. Infections, even low grade infections need to be treated with herbs, antiparasitic and antifungal medication, anti-fungal supplements and antibiotics when appropriate.
“Replace” essential nutrients for proper utilization of foodstuffs. Digestive enzymes, hydrochloric acid and bile salts are needed for proper digestion. “Restore ” normal GI flora. Probiotics containing bifidobacteria and lactobacillus
dosed from 25 to 100 billion units a day along with prebiotics and fiber.
“Repair, ” L-glutamine along with zinc, omega 3 fish oil, vitamins A, C, E, slippery elm and aloe vera containing supplements rebuilds the damaged intestinal wall.
Addressing Stress & Adrenal Fatigue Diagnosis: The HPA AXIS Stress Index Panel . A four point saliva test performed in a single day. Normal are high upon awakening and then quickly fall and flatten out by noon.
Treatment begins with reducing stress (easier said than). Proper diet, yoga, Pilates, Qi Gong, meditation, massage and infra red sauna are a few techniques used to successfully control stress. For some a complete lifestyle change may be the only way to better health. Supplements that enhance the adrenal glands include the adaptogenic herbs Rhodiola, Ginseng, and cordyceps , Pregnenolone, DHEA (cortisol precursors), 5 HTP (for sleep, well-being and mood regulation), adrenal glandulars (to balance cortisol and replenish the catecholamines dopamine, norepinephrine, and epinephrine), and if still no relief Cortef (low dose cortisone). 6. Male Hormones and Hair Loss: Natural DHT Blockers Saw Palmetto- Inhibits 5-alpha-reductase. 240-260 mg @ bedtime minimum. (25) Progesterone- “anti-feminizing in men.” Prevents excess conversion of testosterone to estrogen in males by blocking type 2 5alpha reductase. Nettle Root- Can be used topically with Coconut or Olive Oil and Rosemary extract as a shampoo. Pygeum- Inhibits DHT. Commonly used in combination with Saw Palmetto Rosemary Oil- Inhibits DHT. Use as scalp massage Pumpkin Seed Oil- Inhibits DHT. Can mix with apple cider vinegar as salad dressing.
7. Female Hormones and Hair Loss Proper balancing of bioidentical, not synthetic, progesterone to estrogen, will in many cases resolve hair loss. Fix the cause. 8. Alkalinize the Body Maximal DHT conversion occurs when the pH of the body is between 5.0 and 5.5. This corresponds to what is achieved by following the Standard American Diet. (S.A.D.) Alkalinizing the body prevents DHT from binding to hair follicles enabling them to thrive. A liver Detox such as Dr. Clearfield’s Ultimate Paleocleanse will restore scalp pH to at least 7 in two weeks. If the alkaline environment is maintained, hair will regrow, stronger and thicker than before.. Below is a food chart comparing the relative acidity or alkalinity of different food groups to one another. It is evident that the “normal” American sets him or herself up for failure by consuming highly acidic foods.
9. Delayed Food Allergies Do’s: Bone Broth- Helps restore gut barrier (i.e. heals the “leaky gut”) Fermented Vegetables and Beverages (i.e. sauerkraut, kimchi, beet kvass, coconut water kefir, etc.). High in Probiotics Fish and Shellfish- High in omega-3 fats. Eat at least one pound of cold-water, fatty fish per week EPA and DHA needs. Organ Meats- Loaded micronutrients that promote healthy immune function. Micronutrients Vitamins A & D : Immune enhancement. Vitamin D supports proper T-regulatory cell function. Cod liver oil is the best source of A & D. Iodine & Selenium – Crucial for immune health and successful conversion of T4 to T3. Glutathione : Promotes healthy function of T regulatory cells Niacin (B3), Pyridoxine (B6), Vitamin C, Magnesium, Iron, Copper, Zinc, and Manganese . Eliminate Gluten Soy Dairy Eggs Corn Saturated and/or trans fats Processed foods Sugar Substitute For: Salt: Powdered garlic, powdered onion, lemon juice, lime juice, lemon crystals, turmeric, ground cloves, oregano, ground allspice, celery seeds, coriander seeds, ground cardamom seeds Butter/Fat: Olive oil, coconut oil, flaxseed oil, ghee Sugar: Obtain sugar primarily from fruits and vegetables, not concentrated sources. Fruit purees flavored with lemon juice and spices (cinnamon, nutmeg, mint leaves, ginger, vanilla), Stevia, Xylitol in limited quantities. Alcohol :Limited to an occasional glass of wine, beer or spirits. Red wine contains a number of health promoting phytochemicals and antioxidants. Cereals : Nut flours (almond, pecan, walnut, hazelnut, etc.) can be made in a food processor Cheese: Nut cheeses (cashew, dairy, soy free) Milk: Almond milk, coconut milk Protein: Ancient Nutrition Protein Bone Broth Goitrogens (27) In small amounts goitrogens increase the need for iodine. In large quantities they can damage the thyroid. Goitrogens should be limited to 3-6 servings per week. Steaming can reduce the danger by ⅓ and thoroughly cooking them and discarding the water in case of boiling decreases the harm by 90%.
Cruciferous Vegetables C Others Bok Choy Broccoli Brussel Sprouts Cabbage Canola Cauliflower Chinese Cabbage Collard Greens Horseradish Kale Kohlrabi Mustard Greens Radishes Rutabaga Turnips Soy Pine Nuts, Peanuts Millet Strawberries Pears, Peaches Bamboo Shoots Spinach Sweet Potatoes
10. Compounded Formulas
a. Compounded Caffeine Formula (28) i. Caffeine 0.001% to 0.005% in VersaBase shampoo #4 oz (120cc) ii. Shampoo scalp. Leave on 15 minutes and wash off. Repeat daily. b. Zinc pyrithione 1% in topical solution with or without minoxidil 10%. 4oz (29) i. Sig: apply to hair follicles qhs. Cover with shower cap and leave on all night. Wash out in the am. c. Melatonin 1m/mL in VersaBase Shampoo #4őz. (120cc) (30) i. Sig: shampoo daily. Leave on for 10 minutes and then wash off. d. Minoxidil 8.5%/Finasteride 0.1% scalp solution #2 oz. (31) i. Sig: apply to hair follicles qhs. Cover with shower cap and leave on all night. Wash out in the am. 11. New Trends Platelet Rich Plasma Platelet-rich plasma (PRP) is created by collecting blood from the patient and spinning it in a centrifuge to separate the platelets from the blood. After applying local anesthetics to the scalp, PRP is combined with an FDA approved biomatrix (Acell) and nutrients, then either injected or via a micro-needling device, or applied to localized areas such as the eyebrows or beard, or the full scalp. PRP contains many growth factors to stimulate the hair follicle restoration. It stimulates inactive or newly implanted hair follicles into an active growth phase. Following up with progesterone or a melatonin based scalp treatment enhances the process. New hair sprouts as early as 2 months. 4-8 months is the typical time frame for hair to thicken and become noticeable. Additional injections may be necessary every 2 years. Recovery time is minimal and pain is usually managed with over the counter ibuprofen or homeopathic remedies such as Arnica Montana and/or Boswellia. “Hair loss reduced and at 3 months it reached normal levels. Hair density reached a peak at 3 months. At 6 months and at 1 year, it was significantly increased, 156.25 ± 37.75 (P < 0.001) and 153.70 ± 39.92 (P < 0.001) respectively, comparing to baseline. Patients
were satisfied with a mean result rating of 7.1 on a scale of 1-10. No remarkable adverse effects were noted.” (32) “A mean increase of 33.6 hairs in the target area and a mean increase in total hair density of 45.9 hairs per cm² compared with baseline values. No side effects were noted during treatment. The data clearly highlight the positive effects of PRP injections on male pattern hair loss and absence of major side effects.” (33) “PRP was found to increase hair regrowth significantly and to decrease hair dystrophy and burning or itching sensation compared with TrA or placebo. Ki-67 levels, which served as markers for cell proliferation, were significantly higher with PRP. No side-effects were noted during treatment.” (34) No Stitch Transplant As advertised, no stitches and no staples. There is little-to-no discomfort (no scalpel involved). Patients resume normal activity after only a few days. The hair line is natural looking with no linear scar. Low Level Laser Therapy Laser light, specifically the red visible wavelengths target tissue molecules. The energy level of the molecules increases and the molecules respond by “working off” the excess energy with adaptive changes. In the case of hair follicles this adaptive change is the stimulation of new, thicker follicular growth. Conclusion Hair loss is as simple as hereditary or an early warning sign of a serious health condition. While, at present, surgical transplant is the only way to overcome Dad’s chrome dome, infections, autoimmune issues, scarring, inadequate protein and essential vitamin deficiencies, medications and stress also plays a role. Proper treatment demands we search for the underlying cause. Call us at 775-359-1222 or email [email protected] to find your answers.
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Dr. William Clearfield
Address : 9550 S McCarran Blvd b, Reno, NV 89523 Phone : 775-359-1222 Fax : 888-977-3503 Email : [email protected] Website : drclearfield.net
References 1. http://ift.tt/2xqUcsS 2. Rogers, N., et al., “Medical treatments for male and female pattern hair loss,” Jour Amer Acad Derm 2008; 59(4):547-66. 3. http://ift.tt/2xYvhZ4 wth-cycle.jpg&imgrefurl=http%3A%2F%2Fwww.oblique.co.nz%2Fhair_health%2Fhairstructure.html&docid=Qa VBvcatbRCqpM&tbnid=4BJnp5uQ83LuVM%3A&vet=10ahUKEwiqvsWW_6DVAhWm7oMKHXpgAgYQMwgqK AMwAw..i&w=400&h=178&bih=635&biw=1351&q=life%20cycle%20of%20a%20hair%20follicle&ved=0ahUKEwi qvsWW_6DVAhWm7oMKHXpgAgYQMwgqKAMwAw&iact=mrc&uact=8 4. K. S. Stenn & R. Paus (1 January 2001). “Controls of Hair Follicle Cycling”. Physiological Reviews. 81 (1): 449–494. PMID 11152763. 5. http://ift.tt/2z75wru 6. http://ift.tt/1H7sk92 7. The Birth of Modern Culture, Digital History, http://ift.tt/2z7ED6S, accessed September 7, 2015. 8. http://ift.tt/2xqUdwW 9. Murray, M., et al., Hair Loss in Women. In Pizzorno, J., and Murray, M., Textbook of Natural Medicine St. Louis: Elsevier/Churchill Livingstone, 2013, p. 1406-08 10. Mounsey., A., et al., “Diagnosing and treating hair loss,” Amer Fam Physician 2009; 80(4):356-62. 11. Kalz, F., “Cicatricial alopecia and vitamin A,” Arch Dermatol 1958; 78:740-43. 12. Mesinkovska, N., et al., “Hair: what is new in diagnosis and management? Female pattern hair loss update,” Dermatol Clin 2013; 31(1):119-27. 13. Rothenberg, Ron, Thyroid Optimization, BHRT Syllabus, A4M Lecture Series, Los Angeles, CA, February 26, 2015, p. 62. 14. Clearfield, W., Patient Mysteries; Are You Thyroid Deficient, Healthy Beginning Magazine, August 31, 2015,
Patient Mysteries: Are you thyroid deficient?
15. http://ift.tt/2yBWiWA or-healthy-hair-skin-and-nails#d89PpsjmUPybGAjQ.97 16. Krause, K., et al., “Vitamin status in patients on chronic anticonvulsant therapy,” Int Jour Vitamin Nutri Res 1982; 5294):375-85. 17. Mock, D., et al., “Biotin catabolism is accelerated in adults receiving long-term therapy with anticonvulsants,” Neurology 1997; 49:1444-47. 18. Wolowa, F., et al., “Zinc sulfate in the treatment of alopecia areata,” (Article in Polish) Przeg Derm 1978; 65:687-96. 19. Murray, M., et al., Hair Loss in Women. In Pizzorno, J., and Murray, M., Textbook of Natural Medicine. St. Louis: Elsevier/Churchill Livingstone, 2013, p. 1406-08. 20. Shmunes, E., “Hypervitaminosis A in a patient with alopecia receiving renal dialysis,” Arch Dermatol 1979; 115:882-83. 21. McKenzie, D, How Much Protein to Prevent Hair Loss, http://ift.tt/2z75y2A November 18, 2015. 22. Moeinvaziri, M., et al., “Iron status in diffuse telogen hair loss among women,” Acta Dermatovenerol Croat 2009; 17(4):279-84. 23. Hard, G., “Non-anemic iron deficiency as an etiologic factor in diffuse loss of hair of the scalp in women,” Acta Derm Venereol 1963; 43:562-69. 24. Reasoner, J., LeakyGut Syndrome in Plain English – and How to Fix It, http://ift.tt/1LYkCkQ, Accessed September 6, 2015 25. Prager, N., et al., “A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5- alpha-reductase in the treatment of androgenic alopecia,” Jour Altern Complement Med 2002;8:143-52. 26. http://ift.tt/2yHL5mT mtDWQAKVYoAl-ZwxINw 27. Kresser, C. Clinician’s Guide to Thyroid Disease, Kresser Institute;2016:5-6 28. Bussoletti, C., et al., “Use of a cosmetic caffeine lotion in the treatment of male androgenetic alopecia,” Jour of Applied Cosmetology 2011; 29(4):167-79. 29. Berger, R., et al., “The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial,” Brit Jour Dermatol 2003; 149(2):354-62. 30. Fischer, T., et al., “Melatonin increases antagen hair rate in women with androgenetic alopecia or diffuse alopecia: results of a pilot randomized controlled trial,” Brit Jour Dermatol 2004; 150:341-45. 31. A4M Module XIV; Module XXIV: The Nuts and Bolts of Writing Prescriptions for Compounded Medications:The Ultimate in Personalized Medicine: Del Ray Beach, Florida, June 24-26, 2014 32. Maria-Angeliki Gkini, Alexandros-Efstratios Kouskoukis, Gregory Tripsianis,1 Dimitris Rigopoulos,2 and Konstantinos Kouskoukis, Study of Platelet-Rich Plasma Injections in the Treatment of Androgenetic Alopecia Through an One-Year Period, J Cutan Aesthet Surg. 2014 Oct-Dec; 7(4): 213–219. doi: 10.4103/0974-2077.150743 33. Gentile P1, Garcovich S2, Bielli A3, Scioli MG3, Orlandi A3, Cervelli V4., The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial. Stem Cells Transl Med. 2015 Nov;4(11):1317-23. doi: 10.5966/sctm.2015-0107. Epub 2015 Sep 23. 34. Trink A1, Sorbellini E, Bezzola P, Rodella L, Rezzani R, Ramot Y, Rinaldi F., A randomized, double-blind, placebo- and active-controlled, half-head study to evaluate the effects of platelet-rich plasma on alopecia areata. Br J Dermatol. 2013 Sep;169(3):690-4. doi: 10.1111/bjd.12397.
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Hair Restoration Project | Dr William Clearfield Reno
Hair Restoration Project | Dr William Clearfield Reno
The Hair Restoration Project PRP technique can treat male and female pattern hair loss, alopecia areata, and eyebrow hypotrichosis
Below there is a lot about thinning hair in Reno…I mean a lot of information. More than you need but it is important that you have the option of knowing everything there is to know about male and female pattern baldness and hair loss treatments in Reno NV. This article is about understanding hair loss and how and why your thinning hair and baldness pattern can be replaced without surgery.
Contact Dr. William Clearfield at the Clearfield Medical Group to schedule your consultation to see if the Hair Restoration Project is right for your male or female pattern baldness. 1-775-359-1222 and go to your website www.drclearfield.net
More information on the “Hair Restoration Project” go to http://ift.tt/2yHJH3y
Who doesn’t admire a fine head of hair? We covet, envy, and even worship a great head of hair..My late great mother, (lung cancer, not from cigarettes, bad but too much casino air, Atlantic CIty, New Jersey) in hospice, on the day before she passed, woke from her morphine induced “sleep”, looked around at us sitting by her bedside, and asked, “How’s my hair?” Her final words. (True, story. To be fair, Mom was always a Jackie Kennedy, never Onassis, wannabe.) Millions aren’t so lucky. In the United States, by age 60, 65% of men, and 80% of women have noticeable hair loss. In total 56 million men and women experience hair loss.(2)
To understand hair loss and what can be done to correct it, we must understand the natural growth, and demise, of a single hair follicle. Hair growth takes place in four phases:(4)
1. ACTIVE GROWTH (ANAGEN) PHASE The active growth phase lasting two to six years. Hair grows 18 to 24 inches before entering into the transitional phase. 80-90% of all hair follicles are in this growth phase on a healthy head. 2. TRANSITIONAL (CATAGEN) PHASE The shortest of the hair cycles lasting one to two weeks occurs when the lower third of the hair follicle is cut off from its blood supply. The hair itself shrinks to 1/6 its expected length. Catagen hair accounts for 2-3% of all follicles at any one time. 3. RESTING PHASE (TELOGEN) PHASE The dormant stage lasting one to four months. 10-15% of all hairs are in the Telogen phase. Telogen hair sheds or is pushed out by new hair follicles as the cycle renews. Ideally only 10-15% of hairs are telogenic. When more than 20% of hair are in this “resting” phase, noticeable thinning occurs. 4. SHEDDING PHASE (EXOGEN) PHASE Hairs in this phase shed easily as the follicles are preparing to return to the Anagen phase.
Types of Hair Loss (5) 1. TELOGEN EFFLUVIUM An abnormally high percentage of hair in the Telogen phase results in an overall thinning of hair. Common causes of this type of hair loss include chronic stress, toxins, fungal infections, nutritional deficiencies, and hormonal imbalances. 2. ANDROGENETIC ALOPECIA “Male-pattern” baldness is not limited to men. In women, the hair thins at the crown or widens in the part. The hair thins revealing a bare scalp. 3. ALOPECIA AREATA Presents as patches of lost hair. Alopecia Areata is usually an autoimmun condition with an association of nail issues also. 4. MISCELLANEOUS TYPES a. Traction from braids, weaves or wigs b. Chemotherapy-Related Hair Loss c. Frontal Fibrosing Alopecia (FFA) d. Lichen Planopilaris (LPP) Etiology of Hair Loss (6) 1. Sub-Optimal Thyroid Function The thyroid is the body’s “gas pedal,” determining how fast, or slow all bodily functions operate. When slowed due to inadequate “fuel,” namely usable thyroid substrate, the oils, fluids and tissues, especially the hair follicles function inadequately. The hair follicles spend an abnormal amount of time, and hence an abnormal number of hair follicles are in the Telogen or resting phase, resulting in a form of Telogen Effluvium. 2. Nutritional Deficiencies Nutritional deficiencies, specifically silica and zinc leads to hair loss. Micronutrient testing is indicated when this is suspected. 3. Stress In 1881, George Miller Beard, M.D., a neurologist and graduate from the New York College of Physicians and Surgeons, described a condition based on excess “nervous energy.” Constant over stimulation of the nervous system from the fast paced American lifestyle resulted in “neurasthenia,” burnout, or nervous exhaustion.
Symptoms of neurasthenia included nervous dyspepsia, insomnia, hysteria, hypochondria, asthma, sick-headache, skin rashes, hay fever, premature baldness, inebriety, hot and cold flashes, nervous exhaustion, brain-collapse, and forms of ‘elementary insanity. The best educated and most sophisticated Americans were the most afflicted. Theodore Roosevelt and Frederic Remington were two prominent figures of their day suffering from “neurasthenia.”
The “cure” was a withdrawal from the modern life, rest and a less hectic lifestyle. Critics countered that urban life in the late nineteenth century had produced a “pathetic, pampered, physically and morally enfeebled 97 pound weaklings, unworthy successors to the stalwart Americans who had fought the Civil War and tamed a continent.”.(7)
Physicians pigeonholed patients into this “nervous energy” category, relieving themselves of more vigilant diagnosis. Early signs of tuberculosis, heart failure and epilepsy were chalked up to neurasthenia and when later discovered to be in error, gave fuel to those who saw this “malady,” as a sham. The term neurasthenia is no longer used to describe any medical condition, but the conditions that lead to its “discovery,” diagnosis and its’ symptoms are remarkably similar to a hormonal condition with distinct diagnostic criteria known as “Adrenal Fatigue.”
The adrenal glands, pea sized organs, sit on top of the kidneys. They produce hormones that regulate blood pressure, electrolytes balance, blood sugar, immune responses, digestion, and stress responses. In regards to the latter, constant unremitting stress, as experienced by nearly everyone in today’s society, hijacks normal hormonal responses, redeploying the adrenals’ resources, in the form of the hormone cortisol, to combat the “evil” of the moment. The other adrenal functions, digestion, immune response, and thyroid hormone production, are temporarily put on hold or slowed until the stress has passed.
Cortisol is our protector. It lies in wait, like the lineup of computer programs opened at startup and running in the background, ready at an instant, when needed, to spring into action. In an ideal world, the stressor passes quickly and the adrenals resume lurking behind the scene awaiting the next crisis. In our non-ideal world, one stress begets a second stress, which begets a third stress, ad infinitum, putting the adrenal gland into permanent overdrive. The body is flooded with cortisol driving the adrenals to handle the stress but eventually it cannot keep up. The result is adrenal “burnout” or fatigue.
The thyroid is exquisitely impacted by the constant flooding and eventual depletion of cortisol. High levels signal the brain to lower the production of stressor hormones. Unfortunately, thyroid hormone is produced in the same pathway and is unwittingly lowered. Recall the critical step of converting T4 to the usable thyroid hormone free T3. Stress hormones affect the enzymes that convert T4 to T3 converting T4 into an inert unusable reverse T3.
Chronically elevated cortisol levels release inflammatory cells which desensitizes thyroid receptors to thyroid hormone. Like diabetics who don’t respond to insulin, adequate thyroid hormone may exist, but the result is inadequate thyroid utilization.
Increased circulatory cortisol increases estrogen in the blood stream. Estrogen increases thyroid binding globulin, tying up T3 and T4, reducing hormone levels to achieve the conversion to free T3. Elevated cortisol levels with its’ inherent state of chronic inflammation can trigger “leaky gut syndrome,” latent infections leading and autoimmune diseases.
Hair follicles accumulate in the resting (Telogen) phase.
4. Sex Hormone Imbalances Male: Excess testosterone metabolizes into dihydrotestosterone (DHT) and estradiol. DHT attaches to hair follicles, effectively strangling them causing “organ” death. The key to preventing, slowing, or possibly reversing the effects of DHT is by inhibiting this conversion of Testosterone into DHT. (Essentially the mechanism of action of hair loss products such as Rogaine.)
Type 2 5alpha reductase is the enzyme that that converts testosterone into DHT. Type 2 5alpha reductase is primarily found in the hair follicles and the prostate gland.
The conversion of too much testosterone to DHT results in androgenetic alopecia. As a man ages he retains estrogen and converts testosterone into estrogen at a higher rate. The result is 1+1=4, the 4 being excess DHT as a result of excess estrogen.
Women: Estrogen dominance is the culprit in women. Child birth, birth control medications, stress, toxins, along with entrance into the perimenopausal arena, creates an estrogen dominant pattern. Estrogen signals the liver to produce inordinate amounts of Thyroid Binding Globulin (TBG). T4, the “storage unit” of the thyroid must convert to T3, the hormone that the “work.” Excess TBG leads to an inability to convert T4 to T3, resulting in a relative hypothyroidism and Telogen Effluvium. Estrogen dominance results in excess DHT, leading to a female version of “male pattern” baldness. (8) Miscellaneous areas to explore if estrogen dominance is ruled out: Heredity, insulin resistance, polycystic ovarian syndrome and a low antioxidant state. (9)
5. Medications Causing Hair Loss (10) Antibiotics: gentamicin, chloramphenicol Anticoagulants: warfarin, heparin Antidepressants: fluoxetine, desipramine, lithium Anticonvulsants: valproic acid, phenytoin, carbamazepine Cardiovascular meds: ACE inhibitors, beta blockers Chemotherapy drugs: doxorubicin, vincristine, etoposide Endocrine drugs: bromocriptine, clomiphene, danazol Gout medications: colchicine, allopurinol Lipid lowering drugs: gemfibrozil, fenofibrate, cholestyramine, clofibrate NSAIDS: ibuprofen, indomethacin, naproxen Reflux/ulcer medications: cimetidine, ranitidine, famotidine Antithyroid drugs: iodine, PTU Retinoids: vitamin A overdose, isotretinoin 6. Trichotillomania- Repetitive hair pulling resulting in hair loss. Considered an OCD variant. Treatment usually includes behavioral therapies, SSRI’s or other drugs to treat OCD. Metabolic therapies include NAC, inositol, L-tryptophan, niacin and vitamin B6.
7. Scarring Alopecia- Resulting from burns, radiation, or other injuries or diseases. Destroys the dermis with permanent hair loss. Rx: Vitamin A 150,000 IU qd for 6 weeks stopped disease progression. Maintenance Rx: 150,000 IU qd for three 6 week periods every year. (11)
Conventional Therapies for Hair Loss (12)
Cyproterone acetate Minoxidil Flutamide Ketoconazole Finasteride Hair Transplantation Dutasteride Light Therapy, Botulinum Toxins Holistic Resolutions to Hair Loss
1. Proper Hypothyroidism Diagnosis & Treatment (13-14)
The thyroid functions as the body’s “gas pedal.” Like Goldilocks, we need it to be just right, not too little, not too much. The gland produces two major hormones, triiodothyronine (T3), the active hormone, and thyroxine (T4), the storage hormone. The thyroid also produces calcitonin, a hormone responsible for calcium balance and bone density and magnesium.
98% of all thyroid disorders results in hypothyroidism. Common symptoms include cold intolerance, unexplained weight gain, fatigue, thinning of the hair, the outer third of the eyebrow, the skin and the nails, increased body fat, energy loss, cognitive loss, memory loss, mood disorders, lowered body temperature (never greater than 97.6 F), fluid retention, and a poor sense of well-being.
When the underlying cause of hypothyroidism is the immune system, not the thyroid per se., and it is not addressed, the treatment will not be effective. 25 percent of patients with autoimmune, Hashimoto’s thyroiditis develop polyglandular syndromes (such as pernicious anemia, diabetes, or adrenal insufficiency) or other autoimmune diseases (such as Sjogren’s syndrome).
2. Key Supplements for Healthy Hair (15)
Biotin- Water-soluble B-vitamin found in green leafy vegetables. Regulates mitochondrial enzymes in hair follicles. Depleted by cigarette smoking, aging, excess alcohol, strenuous exercise, burn victims, shortened gut syndrome (GI resections), achlorhydria, and raw egg consumption. (16-17) Use orally or in essential oil mixture. Dose is 30-100 mcg/day.
Zinc -Promotes cell reproduction, tissue growth and repair of broken tissues. Maintains the oil-secreting glands attached to hair follicles. Study showed that 15 patients with alopecia areata received 45 mg of zinc TID. All had complete return of hair growth within 6 months. (18) Maintenance dose is 15 mg per day along with 1 mg copper as a balance.
N-Acetyl-Cysteine- Precursor to glutathione the most powerful antioxidant in the body. Protects DNA from chemical damage, detoxifies heavy metals, and it keeps arteries and airways open. It activates important functions of the immune system.
B Vitamins (B6, B12)- In the form of Pyridoxal 5-Phosphate (PLP), the B Vitamins act as catalysts to activate the enzymes and chemical reactions to commence the metabolism of keratin and melanin in the hair follicles. B vitamins control hormone release., regulating androgen interaction with hair metabolism. Testosterone breaks down into dihydrotestosterone (DHT). Elevated DHT levels diminishes hair growth by decreasing the length of the anagen, hair growth phase, and the follicle size. Vitamin B6 binds to the testosterone receptors, stopping DHT formation.
Niacin- Vitamin B3 converts carbohydrates into energy, delivers the energy to cells where needed and maintains cell integrity. Niacin is a vasodilator, hence the niacin “flush” so common when taken, “washes” carbohydrates through the body, reducing visceral fat and serum cholesterol. The flush can be minimized by taking niacin with a meal or starting (with a) low dose and gradually increasing its potency. The vasodilator effect of niacin delivers increased oxygen and nutrients to the hair follicle resulting in thicker hair.
Arginine- L-arginine, a precursor to nitrogen oxide, opens the potassium channels of the cell, improving blood supply to the hair root.
Lysine- An essential amino acid, lysine stimulates collagen and is necessary for restoring damaged hair. Food sources for lysine include fish (especially salmon, sardines and cod), dairy, poultry, red meat, pork, legumes, nuts, spirulina and pulses.
Saw Palmetto (for Men)- Prevents conversion of testosterone to DHT
Acetyl-L-Carnitine- Up regulates proliferation and down regulates apoptosis in hair follicle keratinocytes. Turns fat into energy. Acetyl-L Carnitine improves the membrane potential of the hair follicle which is significantly diminished along with potassium channel function within withering hair follicles.
Iron- A lack of iron results in a decrease in hemoglobin, the ingredient that carries oxygen for growth and repair of all cells including hair follicles. Iron deficiency states move hair follicles into a premature and prolonged telogen (resting) phase. Hair growth is a “non-essential” bodily function. It is one of the first systems to shut down in a state of iron deficiency. Hence, hair loss is an early warning sign of iron deficiency anemia.
Vitamin D- Essential for calcium homeostasis, immune regulation and cell growth. A host of autoimmune diseases, including alopecia areata, exhibit low levels of Vitamin D. The severity of serum 25(OH)D deficiency is inversely related to the severity of hair loss.
Gluten- Hair loss is an early sign of gluten intolerance. In all cases of alopecia or extensive hair loss, we recommend a strict gluten free diet for 4 weeks as a trial. (19)
Vitamin A- Hair loss is a symptom of Vitamin A toxicity especially in renal failure. Usually resolves when toxicity is addressed. (20)
Emu Oil- Contains linolenic acid a potent 5-alpha reductase inhibitor. Compound with virgin coconut oil to create an antibacterial, anti-inflammatory scalp treatment to DHT.
3. Adequate Protein Insufficient protein effects on your hair growth. The CDC recommends 46 to 56 grams of protein per tain to maintain hair growth. (21) Inadequate protein results in protein rationing by shutting down less important functions.
4. Iron When iron levels fall below 30 mg/L hair growth and regeneration are decreased. Iron deficiency commonly causes hair to be brittle and dry with narrowing or splitting of the hair shaft. Iron replacement restored hair growth in those whose sole issue was iron deficiency. (22-23)
5. GI Evaluation-The 4 R’s Depleted stomach acid leads to impaired protein digestion and decreased nutrient absorption. Disturbed GI flora leads to inadequate nutrient utilization. Pancreatic enzyme deficiency leads to malabsorption of essential fatty acids and zinc.
The “4 R’s” include: (24)
“Remove” inflammatory foods such as gluten, dairy, corn, soy, eggs and sugar. Eliminate gastric irritants like alcohol, caffeine or drugs. Infections, even low grade infections need to be treated with herbs, antiparasitic and antifungal medication, anti-fungal supplements and antibiotics when appropriate.
“Replace” essential nutrients for proper utilization of foodstuffs. Digestive enzymes, hydrochloric acid and bile salts are needed for proper digestion. “Restore ” normal GI flora. Probiotics containing bifidobacteria and lactobacillus
dosed from 25 to 100 billion units a day along with prebiotics and fiber.
“Repair, ” L-glutamine along with zinc, omega 3 fish oil, vitamins A, C, E, slippery elm and aloe vera containing supplements rebuilds the damaged intestinal wall.
Addressing Stress & Adrenal Fatigue Diagnosis: The HPA AXIS Stress Index Panel . A four point saliva test performed in a single day. Normal are high upon awakening and then quickly fall and flatten out by noon.
Treatment begins with reducing stress (easier said than). Proper diet, yoga, Pilates, Qi Gong, meditation, massage and infra red sauna are a few techniques used to successfully control stress. For some a complete lifestyle change may be the only way to better health. Supplements that enhance the adrenal glands include the adaptogenic herbs Rhodiola, Ginseng, and cordyceps , Pregnenolone, DHEA (cortisol precursors), 5 HTP (for sleep, well-being and mood regulation), adrenal glandulars (to balance cortisol and replenish the catecholamines dopamine, norepinephrine, and epinephrine), and if still no relief Cortef (low dose cortisone). 6. Male Hormones and Hair Loss: Natural DHT Blockers Saw Palmetto- Inhibits 5-alpha-reductase. 240-260 mg @ bedtime minimum. (25) Progesterone- “anti-feminizing in men.” Prevents excess conversion of testosterone to estrogen in males by blocking type 2 5alpha reductase. Nettle Root- Can be used topically with Coconut or Olive Oil and Rosemary extract as a shampoo. Pygeum- Inhibits DHT. Commonly used in combination with Saw Palmetto Rosemary Oil- Inhibits DHT. Use as scalp massage Pumpkin Seed Oil- Inhibits DHT. Can mix with apple cider vinegar as salad dressing.
7. Female Hormones and Hair Loss Proper balancing of bioidentical, not synthetic, progesterone to estrogen, will in many cases resolve hair loss. Fix the cause. 8. Alkalinize the Body Maximal DHT conversion occurs when the pH of the body is between 5.0 and 5.5. This corresponds to what is achieved by following the Standard American Diet. (S.A.D.) Alkalinizing the body prevents DHT from binding to hair follicles enabling them to thrive. A liver Detox such as Dr. Clearfield’s Ultimate Paleocleanse will restore scalp pH to at least 7 in two weeks. If the alkaline environment is maintained, hair will regrow, stronger and thicker than before.. Below is a food chart comparing the relative acidity or alkalinity of different food groups to one another. It is evident that the “normal” American sets him or herself up for failure by consuming highly acidic foods.
9. Delayed Food Allergies Do’s: Bone Broth- Helps restore gut barrier (i.e. heals the “leaky gut”) Fermented Vegetables and Beverages (i.e. sauerkraut, kimchi, beet kvass, coconut water kefir, etc.). High in Probiotics Fish and Shellfish- High in omega-3 fats. Eat at least one pound of cold-water, fatty fish per week EPA and DHA needs. Organ Meats- Loaded micronutrients that promote healthy immune function. Micronutrients Vitamins A & D : Immune enhancement. Vitamin D supports proper T-regulatory cell function. Cod liver oil is the best source of A & D. Iodine & Selenium – Crucial for immune health and successful conversion of T4 to T3. Glutathione : Promotes healthy function of T regulatory cells Niacin (B3), Pyridoxine (B6), Vitamin C, Magnesium, Iron, Copper, Zinc, and Manganese . Eliminate Gluten Soy Dairy Eggs Corn Saturated and/or trans fats Processed foods Sugar Substitute For: Salt: Powdered garlic, powdered onion, lemon juice, lime juice, lemon crystals, turmeric, ground cloves, oregano, ground allspice, celery seeds, coriander seeds, ground cardamom seeds Butter/Fat: Olive oil, coconut oil, flaxseed oil, ghee Sugar: Obtain sugar primarily from fruits and vegetables, not concentrated sources. Fruit purees flavored with lemon juice and spices (cinnamon, nutmeg, mint leaves, ginger, vanilla), Stevia, Xylitol in limited quantities. Alcohol :Limited to an occasional glass of wine, beer or spirits. Red wine contains a number of health promoting phytochemicals and antioxidants. Cereals : Nut flours (almond, pecan, walnut, hazelnut, etc.) can be made in a food processor Cheese: Nut cheeses (cashew, dairy, soy free) Milk: Almond milk, coconut milk Protein: Ancient Nutrition Protein Bone Broth Goitrogens (27) In small amounts goitrogens increase the need for iodine. In large quantities they can damage the thyroid. Goitrogens should be limited to 3-6 servings per week. Steaming can reduce the danger by ⅓ and thoroughly cooking them and discarding the water in case of boiling decreases the harm by 90%.
Cruciferous Vegetables C Others Bok Choy Broccoli Brussel Sprouts Cabbage Canola Cauliflower Chinese Cabbage Collard Greens Horseradish Kale Kohlrabi Mustard Greens Radishes Rutabaga Turnips Soy Pine Nuts, Peanuts Millet Strawberries Pears, Peaches Bamboo Shoots Spinach Sweet Potatoes
10. Compounded Formulas
a. Compounded Caffeine Formula (28) i. Caffeine 0.001% to 0.005% in VersaBase shampoo #4 oz (120cc) ii. Shampoo scalp. Leave on 15 minutes and wash off. Repeat daily. b. Zinc pyrithione 1% in topical solution with or without minoxidil 10%. 4oz (29) i. Sig: apply to hair follicles qhs. Cover with shower cap and leave on all night. Wash out in the am. c. Melatonin 1m/mL in VersaBase Shampoo #4őz. (120cc) (30) i. Sig: shampoo daily. Leave on for 10 minutes and then wash off. d. Minoxidil 8.5%/Finasteride 0.1% scalp solution #2 oz. (31) i. Sig: apply to hair follicles qhs. Cover with shower cap and leave on all night. Wash out in the am. 11. New Trends Platelet Rich Plasma Platelet-rich plasma (PRP) is created by collecting blood from the patient and spinning it in a centrifuge to separate the platelets from the blood. After applying local anesthetics to the scalp, PRP is combined with an FDA approved biomatrix (Acell) and nutrients, then either injected or via a micro-needling device, or applied to localized areas such as the eyebrows or beard, or the full scalp. PRP contains many growth factors to stimulate the hair follicle restoration. It stimulates inactive or newly implanted hair follicles into an active growth phase. Following up with progesterone or a melatonin based scalp treatment enhances the process. New hair sprouts as early as 2 months. 4-8 months is the typical time frame for hair to thicken and become noticeable. Additional injections may be necessary every 2 years. Recovery time is minimal and pain is usually managed with over the counter ibuprofen or homeopathic remedies such as Arnica Montana and/or Boswellia. “Hair loss reduced and at 3 months it reached normal levels. Hair density reached a peak at 3 months. At 6 months and at 1 year, it was significantly increased, 156.25 ± 37.75 (P < 0.001) and 153.70 ± 39.92 (P < 0.001) respectively, comparing to baseline. Patients
were satisfied with a mean result rating of 7.1 on a scale of 1-10. No remarkable adverse effects were noted.” (32) “A mean increase of 33.6 hairs in the target area and a mean increase in total hair density of 45.9 hairs per cm² compared with baseline values. No side effects were noted during treatment. The data clearly highlight the positive effects of PRP injections on male pattern hair loss and absence of major side effects.” (33) “PRP was found to increase hair regrowth significantly and to decrease hair dystrophy and burning or itching sensation compared with TrA or placebo. Ki-67 levels, which served as markers for cell proliferation, were significantly higher with PRP. No side-effects were noted during treatment.” (34) No Stitch Transplant As advertised, no stitches and no staples. There is little-to-no discomfort (no scalpel involved). Patients resume normal activity after only a few days. The hair line is natural looking with no linear scar. Low Level Laser Therapy Laser light, specifically the red visible wavelengths target tissue molecules. The energy level of the molecules increases and the molecules respond by “working off” the excess energy with adaptive changes. In the case of hair follicles this adaptive change is the stimulation of new, thicker follicular growth. Conclusion Hair loss is as simple as hereditary or an early warning sign of a serious health condition. While, at present, surgical transplant is the only way to overcome Dad’s chrome dome, infections, autoimmune issues, scarring, inadequate protein and essential vitamin deficiencies, medications and stress also plays a role. Proper treatment demands we search for the underlying cause. Call us at 775-359-1222 or email [email protected] to find your answers.
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Dr. William Clearfield
Address : 9550 S McCarran Blvd b, Reno, NV 89523 Phone : 775-359-1222 Fax : 888-977-3503 Email : [email protected] Website : drclearfield.net
References 1. http://ift.tt/2xqUcsS 2. Rogers, N., et al., “Medical treatments for male and female pattern hair loss,” Jour Amer Acad Derm 2008; 59(4):547-66. 3. http://ift.tt/2xYvhZ4 wth-cycle.jpg&imgrefurl=http%3A%2F%2Fwww.oblique.co.nz%2Fhair_health%2Fhairstructure.html&docid=Qa VBvcatbRCqpM&tbnid=4BJnp5uQ83LuVM%3A&vet=10ahUKEwiqvsWW_6DVAhWm7oMKHXpgAgYQMwgqK AMwAw..i&w=400&h=178&bih=635&biw=1351&q=life%20cycle%20of%20a%20hair%20follicle&ved=0ahUKEwi qvsWW_6DVAhWm7oMKHXpgAgYQMwgqKAMwAw&iact=mrc&uact=8 4. K. S. Stenn & R. Paus (1 January 2001). “Controls of Hair Follicle Cycling”. Physiological Reviews. 81 (1): 449–494. PMID 11152763. 5. http://ift.tt/2z75wru 6. http://ift.tt/1H7sk92 7. The Birth of Modern Culture, Digital History, http://ift.tt/2z7ED6S, accessed September 7, 2015. 8. http://ift.tt/2xqUdwW 9. Murray, M., et al., Hair Loss in Women. In Pizzorno, J., and Murray, M., Textbook of Natural Medicine St. Louis: Elsevier/Churchill Livingstone, 2013, p. 1406-08 10. Mounsey., A., et al., “Diagnosing and treating hair loss,” Amer Fam Physician 2009; 80(4):356-62. 11. Kalz, F., “Cicatricial alopecia and vitamin A,” Arch Dermatol 1958; 78:740-43. 12. Mesinkovska, N., et al., “Hair: what is new in diagnosis and management? Female pattern hair loss update,” Dermatol Clin 2013; 31(1):119-27. 13. Rothenberg, Ron, Thyroid Optimization, BHRT Syllabus, A4M Lecture Series, Los Angeles, CA, February 26, 2015, p. 62. 14. Clearfield, W., Patient Mysteries; Are You Thyroid Deficient, Healthy Beginning Magazine, August 31, 2015,
Patient Mysteries: Are you thyroid deficient?
15. http://ift.tt/2yBWiWA or-healthy-hair-skin-and-nails#d89PpsjmUPybGAjQ.97 16. Krause, K., et al., “Vitamin status in patients on chronic anticonvulsant therapy,” Int Jour Vitamin Nutri Res 1982; 5294):375-85. 17. Mock, D., et al., “Biotin catabolism is accelerated in adults receiving long-term therapy with anticonvulsants,” Neurology 1997; 49:1444-47. 18. Wolowa, F., et al., “Zinc sulfate in the treatment of alopecia areata,” (Article in Polish) Przeg Derm 1978; 65:687-96. 19. Murray, M., et al., Hair Loss in Women. In Pizzorno, J., and Murray, M., Textbook of Natural Medicine. St. Louis: Elsevier/Churchill Livingstone, 2013, p. 1406-08. 20. Shmunes, E., “Hypervitaminosis A in a patient with alopecia receiving renal dialysis,” Arch Dermatol 1979; 115:882-83. 21. McKenzie, D, How Much Protein to Prevent Hair Loss, http://ift.tt/2z75y2A November 18, 2015. 22. Moeinvaziri, M., et al., “Iron status in diffuse telogen hair loss among women,” Acta Dermatovenerol Croat 2009; 17(4):279-84. 23. Hard, G., “Non-anemic iron deficiency as an etiologic factor in diffuse loss of hair of the scalp in women,” Acta Derm Venereol 1963; 43:562-69. 24. Reasoner, J., LeakyGut Syndrome in Plain English – and How to Fix It, http://ift.tt/1LYkCkQ, Accessed September 6, 2015 25. Prager, N., et al., “A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5- alpha-reductase in the treatment of androgenic alopecia,” Jour Altern Complement Med 2002;8:143-52. 26. http://ift.tt/2yHL5mT mtDWQAKVYoAl-ZwxINw 27. Kresser, C. Clinician’s Guide to Thyroid Disease, Kresser Institute;2016:5-6 28. Bussoletti, C., et al., “Use of a cosmetic caffeine lotion in the treatment of male androgenetic alopecia,” Jour of Applied Cosmetology 2011; 29(4):167-79. 29. Berger, R., et al., “The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial,” Brit Jour Dermatol 2003; 149(2):354-62. 30. Fischer, T., et al., “Melatonin increases antagen hair rate in women with androgenetic alopecia or diffuse alopecia: results of a pilot randomized controlled trial,” Brit Jour Dermatol 2004; 150:341-45. 31. A4M Module XIV; Module XXIV: The Nuts and Bolts of Writing Prescriptions for Compounded Medications:The Ultimate in Personalized Medicine: Del Ray Beach, Florida, June 24-26, 2014 32. Maria-Angeliki Gkini, Alexandros-Efstratios Kouskoukis, Gregory Tripsianis,1 Dimitris Rigopoulos,2 and Konstantinos Kouskoukis, Study of Platelet-Rich Plasma Injections in the Treatment of Androgenetic Alopecia Through an One-Year Period, J Cutan Aesthet Surg. 2014 Oct-Dec; 7(4): 213–219. doi: 10.4103/0974-2077.150743 33. Gentile P1, Garcovich S2, Bielli A3, Scioli MG3, Orlandi A3, Cervelli V4., The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial. Stem Cells Transl Med. 2015 Nov;4(11):1317-23. doi: 10.5966/sctm.2015-0107. Epub 2015 Sep 23. 34. Trink A1, Sorbellini E, Bezzola P, Rodella L, Rezzani R, Ramot Y, Rinaldi F., A randomized, double-blind, placebo- and active-controlled, half-head study to evaluate the effects of platelet-rich plasma on alopecia areata. Br J Dermatol. 2013 Sep;169(3):690-4. doi: 10.1111/bjd.12397.
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Hair Restoration Project | Dr William Clearfield Reno
Hair Restoration Project | Dr William Clearfield Reno
The Hair Restoration Project PRP technique can treat male and female pattern hair loss, alopecia areata, and eyebrow hypotrichosis
Below there is a lot about thinning hair in Reno…I mean a lot of information. More than you need but it is important that you have the option of knowing everything there is to know about male and female pattern baldness and hair loss treatments in Reno NV. This article is about understanding hair loss and how and why your thinning hair and baldness pattern can be replaced without surgery.
Contact Dr. William Clearfield at the Clearfield Medical Group to schedule your consultation to see if the Hair Restoration Project is right for your male or female pattern baldness. 1-775-359-1222 and go to your website www.drclearfield.net
More information on the “Hair Restoration Project” go to http://ift.tt/2yHJH3y
Who doesn’t admire a fine head of hair? We covet, envy, and even worship a great head of hair..My late great mother, (lung cancer, not from cigarettes, bad but too much casino air, Atlantic CIty, New Jersey) in hospice, on the day before she passed, woke from her morphine induced “sleep”, looked around at us sitting by her bedside, and asked, “How’s my hair?” Her final words. (True, story. To be fair, Mom was always a Jackie Kennedy, never Onassis, wannabe.) Millions aren’t so lucky. In the United States, by age 60, 65% of men, and 80% of women have noticeable hair loss. In total 56 million men and women experience hair loss.(2)
To understand hair loss and what can be done to correct it, we must understand the natural growth, and demise, of a single hair follicle. Hair growth takes place in four phases:(4)
1. ACTIVE GROWTH (ANAGEN) PHASE The active growth phase lasting two to six years. Hair grows 18 to 24 inches before entering into the transitional phase. 80-90% of all hair follicles are in this growth phase on a healthy head. 2. TRANSITIONAL (CATAGEN) PHASE The shortest of the hair cycles lasting one to two weeks occurs when the lower third of the hair follicle is cut off from its blood supply. The hair itself shrinks to 1/6 its expected length. Catagen hair accounts for 2-3% of all follicles at any one time. 3. RESTING PHASE (TELOGEN) PHASE The dormant stage lasting one to four months. 10-15% of all hairs are in the Telogen phase. Telogen hair sheds or is pushed out by new hair follicles as the cycle renews. Ideally only 10-15% of hairs are telogenic. When more than 20% of hair are in this “resting” phase, noticeable thinning occurs. 4. SHEDDING PHASE (EXOGEN) PHASE Hairs in this phase shed easily as the follicles are preparing to return to the Anagen phase.
Types of Hair Loss (5) 1. TELOGEN EFFLUVIUM An abnormally high percentage of hair in the Telogen phase results in an overall thinning of hair. Common causes of this type of hair loss include chronic stress, toxins, fungal infections, nutritional deficiencies, and hormonal imbalances. 2. ANDROGENETIC ALOPECIA “Male-pattern” baldness is not limited to men. In women, the hair thins at the crown or widens in the part. The hair thins revealing a bare scalp. 3. ALOPECIA AREATA Presents as patches of lost hair. Alopecia Areata is usually an autoimmun condition with an association of nail issues also. 4. MISCELLANEOUS TYPES a. Traction from braids, weaves or wigs b. Chemotherapy-Related Hair Loss c. Frontal Fibrosing Alopecia (FFA) d. Lichen Planopilaris (LPP) Etiology of Hair Loss (6) 1. Sub-Optimal Thyroid Function The thyroid is the body’s “gas pedal,” determining how fast, or slow all bodily functions operate. When slowed due to inadequate “fuel,” namely usable thyroid substrate, the oils, fluids and tissues, especially the hair follicles function inadequately. The hair follicles spend an abnormal amount of time, and hence an abnormal number of hair follicles are in the Telogen or resting phase, resulting in a form of Telogen Effluvium. 2. Nutritional Deficiencies Nutritional deficiencies, specifically silica and zinc leads to hair loss. Micronutrient testing is indicated when this is suspected. 3. Stress In 1881, George Miller Beard, M.D., a neurologist and graduate from the New York College of Physicians and Surgeons, described a condition based on excess “nervous energy.” Constant over stimulation of the nervous system from the fast paced American lifestyle resulted in “neurasthenia,” burnout, or nervous exhaustion.
Symptoms of neurasthenia included nervous dyspepsia, insomnia, hysteria, hypochondria, asthma, sick-headache, skin rashes, hay fever, premature baldness, inebriety, hot and cold flashes, nervous exhaustion, brain-collapse, and forms of ‘elementary insanity. The best educated and most sophisticated Americans were the most afflicted. Theodore Roosevelt and Frederic Remington were two prominent figures of their day suffering from “neurasthenia.”
The “cure” was a withdrawal from the modern life, rest and a less hectic lifestyle. Critics countered that urban life in the late nineteenth century had produced a “pathetic, pampered, physically and morally enfeebled 97 pound weaklings, unworthy successors to the stalwart Americans who had fought the Civil War and tamed a continent.”.(7)
Physicians pigeonholed patients into this “nervous energy” category, relieving themselves of more vigilant diagnosis. Early signs of tuberculosis, heart failure and epilepsy were chalked up to neurasthenia and when later discovered to be in error, gave fuel to those who saw this “malady,” as a sham. The term neurasthenia is no longer used to describe any medical condition, but the conditions that lead to its “discovery,” diagnosis and its’ symptoms are remarkably similar to a hormonal condition with distinct diagnostic criteria known as “Adrenal Fatigue.”
The adrenal glands, pea sized organs, sit on top of the kidneys. They produce hormones that regulate blood pressure, electrolytes balance, blood sugar, immune responses, digestion, and stress responses. In regards to the latter, constant unremitting stress, as experienced by nearly everyone in today’s society, hijacks normal hormonal responses, redeploying the adrenals’ resources, in the form of the hormone cortisol, to combat the “evil” of the moment. The other adrenal functions, digestion, immune response, and thyroid hormone production, are temporarily put on hold or slowed until the stress has passed.
Cortisol is our protector. It lies in wait, like the lineup of computer programs opened at startup and running in the background, ready at an instant, when needed, to spring into action. In an ideal world, the stressor passes quickly and the adrenals resume lurking behind the scene awaiting the next crisis. In our non-ideal world, one stress begets a second stress, which begets a third stress, ad infinitum, putting the adrenal gland into permanent overdrive. The body is flooded with cortisol driving the adrenals to handle the stress but eventually it cannot keep up. The result is adrenal “burnout” or fatigue.
The thyroid is exquisitely impacted by the constant flooding and eventual depletion of cortisol. High levels signal the brain to lower the production of stressor hormones. Unfortunately, thyroid hormone is produced in the same pathway and is unwittingly lowered. Recall the critical step of converting T4 to the usable thyroid hormone free T3. Stress hormones affect the enzymes that convert T4 to T3 converting T4 into an inert unusable reverse T3.
Chronically elevated cortisol levels release inflammatory cells which desensitizes thyroid receptors to thyroid hormone. Like diabetics who don’t respond to insulin, adequate thyroid hormone may exist, but the result is inadequate thyroid utilization.
Increased circulatory cortisol increases estrogen in the blood stream. Estrogen increases thyroid binding globulin, tying up T3 and T4, reducing hormone levels to achieve the conversion to free T3. Elevated cortisol levels with its’ inherent state of chronic inflammation can trigger “leaky gut syndrome,” latent infections leading and autoimmune diseases.
Hair follicles accumulate in the resting (Telogen) phase.
4. Sex Hormone Imbalances Male: Excess testosterone metabolizes into dihydrotestosterone (DHT) and estradiol. DHT attaches to hair follicles, effectively strangling them causing “organ” death. The key to preventing, slowing, or possibly reversing the effects of DHT is by inhibiting this conversion of Testosterone into DHT. (Essentially the mechanism of action of hair loss products such as Rogaine.)
Type 2 5alpha reductase is the enzyme that that converts testosterone into DHT. Type 2 5alpha reductase is primarily found in the hair follicles and the prostate gland.
The conversion of too much testosterone to DHT results in androgenetic alopecia. As a man ages he retains estrogen and converts testosterone into estrogen at a higher rate. The result is 1+1=4, the 4 being excess DHT as a result of excess estrogen.
Women: Estrogen dominance is the culprit in women. Child birth, birth control medications, stress, toxins, along with entrance into the perimenopausal arena, creates an estrogen dominant pattern. Estrogen signals the liver to produce inordinate amounts of Thyroid Binding Globulin (TBG). T4, the “storage unit” of the thyroid must convert to T3, the hormone that the “work.” Excess TBG leads to an inability to convert T4 to T3, resulting in a relative hypothyroidism and Telogen Effluvium. Estrogen dominance results in excess DHT, leading to a female version of “male pattern” baldness. (8) Miscellaneous areas to explore if estrogen dominance is ruled out: Heredity, insulin resistance, polycystic ovarian syndrome and a low antioxidant state. (9)
5. Medications Causing Hair Loss (10) Antibiotics: gentamicin, chloramphenicol Anticoagulants: warfarin, heparin Antidepressants: fluoxetine, desipramine, lithium Anticonvulsants: valproic acid, phenytoin, carbamazepine Cardiovascular meds: ACE inhibitors, beta blockers Chemotherapy drugs: doxorubicin, vincristine, etoposide Endocrine drugs: bromocriptine, clomiphene, danazol Gout medications: colchicine, allopurinol Lipid lowering drugs: gemfibrozil, fenofibrate, cholestyramine, clofibrate NSAIDS: ibuprofen, indomethacin, naproxen Reflux/ulcer medications: cimetidine, ranitidine, famotidine Antithyroid drugs: iodine, PTU Retinoids: vitamin A overdose, isotretinoin 6. Trichotillomania- Repetitive hair pulling resulting in hair loss. Considered an OCD variant. Treatment usually includes behavioral therapies, SSRI’s or other drugs to treat OCD. Metabolic therapies include NAC, inositol, L-tryptophan, niacin and vitamin B6.
7. Scarring Alopecia- Resulting from burns, radiation, or other injuries or diseases. Destroys the dermis with permanent hair loss. Rx: Vitamin A 150,000 IU qd for 6 weeks stopped disease progression. Maintenance Rx: 150,000 IU qd for three 6 week periods every year. (11)
Conventional Therapies for Hair Loss (12)
Cyproterone acetate Minoxidil Flutamide Ketoconazole Finasteride Hair Transplantation Dutasteride Light Therapy, Botulinum Toxins Holistic Resolutions to Hair Loss
1. Proper Hypothyroidism Diagnosis & Treatment (13-14)
The thyroid functions as the body’s “gas pedal.” Like Goldilocks, we need it to be just right, not too little, not too much. The gland produces two major hormones, triiodothyronine (T3), the active hormone, and thyroxine (T4), the storage hormone. The thyroid also produces calcitonin, a hormone responsible for calcium balance and bone density and magnesium.
98% of all thyroid disorders results in hypothyroidism. Common symptoms include cold intolerance, unexplained weight gain, fatigue, thinning of the hair, the outer third of the eyebrow, the skin and the nails, increased body fat, energy loss, cognitive loss, memory loss, mood disorders, lowered body temperature (never greater than 97.6 F), fluid retention, and a poor sense of well-being.
When the underlying cause of hypothyroidism is the immune system, not the thyroid per se., and it is not addressed, the treatment will not be effective. 25 percent of patients with autoimmune, Hashimoto’s thyroiditis develop polyglandular syndromes (such as pernicious anemia, diabetes, or adrenal insufficiency) or other autoimmune diseases (such as Sjogren’s syndrome).
2. Key Supplements for Healthy Hair (15)
Biotin- Water-soluble B-vitamin found in green leafy vegetables. Regulates mitochondrial enzymes in hair follicles. Depleted by cigarette smoking, aging, excess alcohol, strenuous exercise, burn victims, shortened gut syndrome (GI resections), achlorhydria, and raw egg consumption. (16-17) Use orally or in essential oil mixture. Dose is 30-100 mcg/day.
Zinc -Promotes cell reproduction, tissue growth and repair of broken tissues. Maintains the oil-secreting glands attached to hair follicles. Study showed that 15 patients with alopecia areata received 45 mg of zinc TID. All had complete return of hair growth within 6 months. (18) Maintenance dose is 15 mg per day along with 1 mg copper as a balance.
N-Acetyl-Cysteine- Precursor to glutathione the most powerful antioxidant in the body. Protects DNA from chemical damage, detoxifies heavy metals, and it keeps arteries and airways open. It activates important functions of the immune system.
B Vitamins (B6, B12)- In the form of Pyridoxal 5-Phosphate (PLP), the B Vitamins act as catalysts to activate the enzymes and chemical reactions to commence the metabolism of keratin and melanin in the hair follicles. B vitamins control hormone release., regulating androgen interaction with hair metabolism. Testosterone breaks down into dihydrotestosterone (DHT). Elevated DHT levels diminishes hair growth by decreasing the length of the anagen, hair growth phase, and the follicle size. Vitamin B6 binds to the testosterone receptors, stopping DHT formation.
Niacin- Vitamin B3 converts carbohydrates into energy, delivers the energy to cells where needed and maintains cell integrity. Niacin is a vasodilator, hence the niacin “flush” so common when taken, “washes” carbohydrates through the body, reducing visceral fat and serum cholesterol. The flush can be minimized by taking niacin with a meal or starting (with a) low dose and gradually increasing its potency. The vasodilator effect of niacin delivers increased oxygen and nutrients to the hair follicle resulting in thicker hair.
Arginine- L-arginine, a precursor to nitrogen oxide, opens the potassium channels of the cell, improving blood supply to the hair root.
Lysine- An essential amino acid, lysine stimulates collagen and is necessary for restoring damaged hair. Food sources for lysine include fish (especially salmon, sardines and cod), dairy, poultry, red meat, pork, legumes, nuts, spirulina and pulses.
Saw Palmetto (for Men)- Prevents conversion of testosterone to DHT
Acetyl-L-Carnitine- Up regulates proliferation and down regulates apoptosis in hair follicle keratinocytes. Turns fat into energy. Acetyl-L Carnitine improves the membrane potential of the hair follicle which is significantly diminished along with potassium channel function within withering hair follicles.
Iron- A lack of iron results in a decrease in hemoglobin, the ingredient that carries oxygen for growth and repair of all cells including hair follicles. Iron deficiency states move hair follicles into a premature and prolonged telogen (resting) phase. Hair growth is a “non-essential” bodily function. It is one of the first systems to shut down in a state of iron deficiency. Hence, hair loss is an early warning sign of iron deficiency anemia.
Vitamin D- Essential for calcium homeostasis, immune regulation and cell growth. A host of autoimmune diseases, including alopecia areata, exhibit low levels of Vitamin D. The severity of serum 25(OH)D deficiency is inversely related to the severity of hair loss.
Gluten- Hair loss is an early sign of gluten intolerance. In all cases of alopecia or extensive hair loss, we recommend a strict gluten free diet for 4 weeks as a trial. (19)
Vitamin A- Hair loss is a symptom of Vitamin A toxicity especially in renal failure. Usually resolves when toxicity is addressed. (20)
Emu Oil- Contains linolenic acid a potent 5-alpha reductase inhibitor. Compound with virgin coconut oil to create an antibacterial, anti-inflammatory scalp treatment to DHT.
3. Adequate Protein Insufficient protein effects on your hair growth. The CDC recommends 46 to 56 grams of protein per tain to maintain hair growth. (21) Inadequate protein results in protein rationing by shutting down less important functions.
4. Iron When iron levels fall below 30 mg/L hair growth and regeneration are decreased. Iron deficiency commonly causes hair to be brittle and dry with narrowing or splitting of the hair shaft. Iron replacement restored hair growth in those whose sole issue was iron deficiency. (22-23)
5. GI Evaluation-The 4 R’s Depleted stomach acid leads to impaired protein digestion and decreased nutrient absorption. Disturbed GI flora leads to inadequate nutrient utilization. Pancreatic enzyme deficiency leads to malabsorption of essential fatty acids and zinc.
The “4 R’s” include: (24)
“Remove” inflammatory foods such as gluten, dairy, corn, soy, eggs and sugar. Eliminate gastric irritants like alcohol, caffeine or drugs. Infections, even low grade infections need to be treated with herbs, antiparasitic and antifungal medication, anti-fungal supplements and antibiotics when appropriate.
“Replace” essential nutrients for proper utilization of foodstuffs. Digestive enzymes, hydrochloric acid and bile salts are needed for proper digestion. “Restore ” normal GI flora. Probiotics containing bifidobacteria and lactobacillus
dosed from 25 to 100 billion units a day along with prebiotics and fiber.
“Repair, ” L-glutamine along with zinc, omega 3 fish oil, vitamins A, C, E, slippery elm and aloe vera containing supplements rebuilds the damaged intestinal wall.
Addressing Stress & Adrenal Fatigue Diagnosis: The HPA AXIS Stress Index Panel . A four point saliva test performed in a single day. Normal are high upon awakening and then quickly fall and flatten out by noon.
Treatment begins with reducing stress (easier said than). Proper diet, yoga, Pilates, Qi Gong, meditation, massage and infra red sauna are a few techniques used to successfully control stress. For some a complete lifestyle change may be the only way to better health. Supplements that enhance the adrenal glands include the adaptogenic herbs Rhodiola, Ginseng, and cordyceps , Pregnenolone, DHEA (cortisol precursors), 5 HTP (for sleep, well-being and mood regulation), adrenal glandulars (to balance cortisol and replenish the catecholamines dopamine, norepinephrine, and epinephrine), and if still no relief Cortef (low dose cortisone). 6. Male Hormones and Hair Loss: Natural DHT Blockers Saw Palmetto- Inhibits 5-alpha-reductase. 240-260 mg @ bedtime minimum. (25) Progesterone- “anti-feminizing in men.” Prevents excess conversion of testosterone to estrogen in males by blocking type 2 5alpha reductase. Nettle Root- Can be used topically with Coconut or Olive Oil and Rosemary extract as a shampoo. Pygeum- Inhibits DHT. Commonly used in combination with Saw Palmetto Rosemary Oil- Inhibits DHT. Use as scalp massage Pumpkin Seed Oil- Inhibits DHT. Can mix with apple cider vinegar as salad dressing.
7. Female Hormones and Hair Loss Proper balancing of bioidentical, not synthetic, progesterone to estrogen, will in many cases resolve hair loss. Fix the cause. 8. Alkalinize the Body Maximal DHT conversion occurs when the pH of the body is between 5.0 and 5.5. This corresponds to what is achieved by following the Standard American Diet. (S.A.D.) Alkalinizing the body prevents DHT from binding to hair follicles enabling them to thrive. A liver Detox such as Dr. Clearfield’s Ultimate Paleocleanse will restore scalp pH to at least 7 in two weeks. If the alkaline environment is maintained, hair will regrow, stronger and thicker than before.. Below is a food chart comparing the relative acidity or alkalinity of different food groups to one another. It is evident that the “normal” American sets him or herself up for failure by consuming highly acidic foods.
9. Delayed Food Allergies Do’s: Bone Broth- Helps restore gut barrier (i.e. heals the “leaky gut”) Fermented Vegetables and Beverages (i.e. sauerkraut, kimchi, beet kvass, coconut water kefir, etc.). High in Probiotics Fish and Shellfish- High in omega-3 fats. Eat at least one pound of cold-water, fatty fish per week EPA and DHA needs. Organ Meats- Loaded micronutrients that promote healthy immune function. Micronutrients Vitamins A & D : Immune enhancement. Vitamin D supports proper T-regulatory cell function. Cod liver oil is the best source of A & D. Iodine & Selenium – Crucial for immune health and successful conversion of T4 to T3. Glutathione : Promotes healthy function of T regulatory cells Niacin (B3), Pyridoxine (B6), Vitamin C, Magnesium, Iron, Copper, Zinc, and Manganese . Eliminate Gluten Soy Dairy Eggs Corn Saturated and/or trans fats Processed foods Sugar Substitute For: Salt: Powdered garlic, powdered onion, lemon juice, lime juice, lemon crystals, turmeric, ground cloves, oregano, ground allspice, celery seeds, coriander seeds, ground cardamom seeds Butter/Fat: Olive oil, coconut oil, flaxseed oil, ghee Sugar: Obtain sugar primarily from fruits and vegetables, not concentrated sources. Fruit purees flavored with lemon juice and spices (cinnamon, nutmeg, mint leaves, ginger, vanilla), Stevia, Xylitol in limited quantities. Alcohol :Limited to an occasional glass of wine, beer or spirits. Red wine contains a number of health promoting phytochemicals and antioxidants. Cereals : Nut flours (almond, pecan, walnut, hazelnut, etc.) can be made in a food processor Cheese: Nut cheeses (cashew, dairy, soy free) Milk: Almond milk, coconut milk Protein: Ancient Nutrition Protein Bone Broth Goitrogens (27) In small amounts goitrogens increase the need for iodine. In large quantities they can damage the thyroid. Goitrogens should be limited to 3-6 servings per week. Steaming can reduce the danger by ⅓ and thoroughly cooking them and discarding the water in case of boiling decreases the harm by 90%.
Cruciferous Vegetables C Others Bok Choy Broccoli Brussel Sprouts Cabbage Canola Cauliflower Chinese Cabbage Collard Greens Horseradish Kale Kohlrabi Mustard Greens Radishes Rutabaga Turnips Soy Pine Nuts, Peanuts Millet Strawberries Pears, Peaches Bamboo Shoots Spinach Sweet Potatoes
10. Compounded Formulas
a. Compounded Caffeine Formula (28) i. Caffeine 0.001% to 0.005% in VersaBase shampoo #4 oz (120cc) ii. Shampoo scalp. Leave on 15 minutes and wash off. Repeat daily. b. Zinc pyrithione 1% in topical solution with or without minoxidil 10%. 4oz (29) i. Sig: apply to hair follicles qhs. Cover with shower cap and leave on all night. Wash out in the am. c. Melatonin 1m/mL in VersaBase Shampoo #4őz. (120cc) (30) i. Sig: shampoo daily. Leave on for 10 minutes and then wash off. d. Minoxidil 8.5%/Finasteride 0.1% scalp solution #2 oz. (31) i. Sig: apply to hair follicles qhs. Cover with shower cap and leave on all night. Wash out in the am. 11. New Trends Platelet Rich Plasma Platelet-rich plasma (PRP) is created by collecting blood from the patient and spinning it in a centrifuge to separate the platelets from the blood. After applying local anesthetics to the scalp, PRP is combined with an FDA approved biomatrix (Acell) and nutrients, then either injected or via a micro-needling device, or applied to localized areas such as the eyebrows or beard, or the full scalp. PRP contains many growth factors to stimulate the hair follicle restoration. It stimulates inactive or newly implanted hair follicles into an active growth phase. Following up with progesterone or a melatonin based scalp treatment enhances the process. New hair sprouts as early as 2 months. 4-8 months is the typical time frame for hair to thicken and become noticeable. Additional injections may be necessary every 2 years. Recovery time is minimal and pain is usually managed with over the counter ibuprofen or homeopathic remedies such as Arnica Montana and/or Boswellia. “Hair loss reduced and at 3 months it reached normal levels. Hair density reached a peak at 3 months. At 6 months and at 1 year, it was significantly increased, 156.25 ± 37.75 (P < 0.001) and 153.70 ± 39.92 (P < 0.001) respectively, comparing to baseline. Patients
were satisfied with a mean result rating of 7.1 on a scale of 1-10. No remarkable adverse effects were noted.” (32) “A mean increase of 33.6 hairs in the target area and a mean increase in total hair density of 45.9 hairs per cm² compared with baseline values. No side effects were noted during treatment. The data clearly highlight the positive effects of PRP injections on male pattern hair loss and absence of major side effects.” (33) “PRP was found to increase hair regrowth significantly and to decrease hair dystrophy and burning or itching sensation compared with TrA or placebo. Ki-67 levels, which served as markers for cell proliferation, were significantly higher with PRP. No side-effects were noted during treatment.” (34) No Stitch Transplant As advertised, no stitches and no staples. There is little-to-no discomfort (no scalpel involved). Patients resume normal activity after only a few days. The hair line is natural looking with no linear scar. Low Level Laser Therapy Laser light, specifically the red visible wavelengths target tissue molecules. The energy level of the molecules increases and the molecules respond by “working off” the excess energy with adaptive changes. In the case of hair follicles this adaptive change is the stimulation of new, thicker follicular growth. Conclusion Hair loss is as simple as hereditary or an early warning sign of a serious health condition. While, at present, surgical transplant is the only way to overcome Dad’s chrome dome, infections, autoimmune issues, scarring, inadequate protein and essential vitamin deficiencies, medications and stress also plays a role. Proper treatment demands we search for the underlying cause. Call us at 775-359-1222 or email [email protected] to find your answers.
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Dr. William Clearfield
Address : 9550 S McCarran Blvd b, Reno, NV 89523 Phone : 775-359-1222 Fax : 888-977-3503 Email : [email protected] Website : drclearfield.net
References 1. http://ift.tt/2xqUcsS 2. Rogers, N., et al., “Medical treatments for male and female pattern hair loss,” Jour Amer Acad Derm 2008; 59(4):547-66. 3. http://ift.tt/2xYvhZ4 wth-cycle.jpg&imgrefurl=http%3A%2F%2Fwww.oblique.co.nz%2Fhair_health%2Fhairstructure.html&docid=Qa VBvcatbRCqpM&tbnid=4BJnp5uQ83LuVM%3A&vet=10ahUKEwiqvsWW_6DVAhWm7oMKHXpgAgYQMwgqK AMwAw..i&w=400&h=178&bih=635&biw=1351&q=life%20cycle%20of%20a%20hair%20follicle&ved=0ahUKEwi qvsWW_6DVAhWm7oMKHXpgAgYQMwgqKAMwAw&iact=mrc&uact=8 4. K. S. Stenn & R. Paus (1 January 2001). “Controls of Hair Follicle Cycling”. Physiological Reviews. 81 (1): 449–494. PMID 11152763. 5. http://ift.tt/2z75wru 6. http://ift.tt/1H7sk92 7. The Birth of Modern Culture, Digital History, http://ift.tt/2z7ED6S, accessed September 7, 2015. 8. http://ift.tt/2xqUdwW 9. Murray, M., et al., Hair Loss in Women. In Pizzorno, J., and Murray, M., Textbook of Natural Medicine St. Louis: Elsevier/Churchill Livingstone, 2013, p. 1406-08 10. Mounsey., A., et al., “Diagnosing and treating hair loss,” Amer Fam Physician 2009; 80(4):356-62. 11. Kalz, F., “Cicatricial alopecia and vitamin A,” Arch Dermatol 1958; 78:740-43. 12. Mesinkovska, N., et al., “Hair: what is new in diagnosis and management? Female pattern hair loss update,” Dermatol Clin 2013; 31(1):119-27. 13. Rothenberg, Ron, Thyroid Optimization, BHRT Syllabus, A4M Lecture Series, Los Angeles, CA, February 26, 2015, p. 62. 14. Clearfield, W., Patient Mysteries; Are You Thyroid Deficient, Healthy Beginning Magazine, August 31, 2015,
Patient Mysteries: Are you thyroid deficient?
15. http://ift.tt/2yBWiWA or-healthy-hair-skin-and-nails#d89PpsjmUPybGAjQ.97 16. Krause, K., et al., “Vitamin status in patients on chronic anticonvulsant therapy,” Int Jour Vitamin Nutri Res 1982; 5294):375-85. 17. Mock, D., et al., “Biotin catabolism is accelerated in adults receiving long-term therapy with anticonvulsants,” Neurology 1997; 49:1444-47. 18. Wolowa, F., et al., “Zinc sulfate in the treatment of alopecia areata,” (Article in Polish) Przeg Derm 1978; 65:687-96. 19. Murray, M., et al., Hair Loss in Women. In Pizzorno, J., and Murray, M., Textbook of Natural Medicine. St. Louis: Elsevier/Churchill Livingstone, 2013, p. 1406-08. 20. Shmunes, E., “Hypervitaminosis A in a patient with alopecia receiving renal dialysis,” Arch Dermatol 1979; 115:882-83. 21. McKenzie, D, How Much Protein to Prevent Hair Loss, http://ift.tt/2z75y2A November 18, 2015. 22. Moeinvaziri, M., et al., “Iron status in diffuse telogen hair loss among women,” Acta Dermatovenerol Croat 2009; 17(4):279-84. 23. Hard, G., “Non-anemic iron deficiency as an etiologic factor in diffuse loss of hair of the scalp in women,” Acta Derm Venereol 1963; 43:562-69. 24. Reasoner, J., LeakyGut Syndrome in Plain English – and How to Fix It, http://ift.tt/1LYkCkQ, Accessed September 6, 2015 25. Prager, N., et al., “A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5- alpha-reductase in the treatment of androgenic alopecia,” Jour Altern Complement Med 2002;8:143-52. 26. http://ift.tt/2yHL5mT mtDWQAKVYoAl-ZwxINw 27. Kresser, C. Clinician’s Guide to Thyroid Disease, Kresser Institute;2016:5-6 28. Bussoletti, C., et al., “Use of a cosmetic caffeine lotion in the treatment of male androgenetic alopecia,” Jour of Applied Cosmetology 2011; 29(4):167-79. 29. Berger, R., et al., “The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial,” Brit Jour Dermatol 2003; 149(2):354-62. 30. Fischer, T., et al., “Melatonin increases antagen hair rate in women with androgenetic alopecia or diffuse alopecia: results of a pilot randomized controlled trial,” Brit Jour Dermatol 2004; 150:341-45. 31. A4M Module XIV; Module XXIV: The Nuts and Bolts of Writing Prescriptions for Compounded Medications:The Ultimate in Personalized Medicine: Del Ray Beach, Florida, June 24-26, 2014 32. Maria-Angeliki Gkini, Alexandros-Efstratios Kouskoukis, Gregory Tripsianis,1 Dimitris Rigopoulos,2 and Konstantinos Kouskoukis, Study of Platelet-Rich Plasma Injections in the Treatment of Androgenetic Alopecia Through an One-Year Period, J Cutan Aesthet Surg. 2014 Oct-Dec; 7(4): 213–219. doi: 10.4103/0974-2077.150743 33. Gentile P1, Garcovich S2, Bielli A3, Scioli MG3, Orlandi A3, Cervelli V4., The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial. Stem Cells Transl Med. 2015 Nov;4(11):1317-23. doi: 10.5966/sctm.2015-0107. Epub 2015 Sep 23. 34. Trink A1, Sorbellini E, Bezzola P, Rodella L, Rezzani R, Ramot Y, Rinaldi F., A randomized, double-blind, placebo- and active-controlled, half-head study to evaluate the effects of platelet-rich plasma on alopecia areata. Br J Dermatol. 2013 Sep;169(3):690-4. doi: 10.1111/bjd.12397.
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Hair Restoration Project | Dr William Clearfield Reno
Hair Restoration Project | Dr William Clearfield Reno
The Hair Restoration Project PRP technique can treat male and female pattern hair loss, alopecia areata, and eyebrow hypotrichosis
Below there is a lot about thinning hair in Reno…I mean a lot of information. More than you need but it is important that you have the option of knowing everything there is to know about male and female pattern baldness and hair loss treatments in Reno NV. This article is about understanding hair loss and how and why your thinning hair and baldness pattern can be replaced without surgery.
Contact Dr. William Clearfield at the Clearfield Medical Group to schedule your consultation to see if the Hair Restoration Project is right for your male or female pattern baldness. 1-775-359-1222 and go to your website www.drclearfield.net
More information on the “Hair Restoration Project” go to http://ift.tt/2yHJH3y
Who doesn’t admire a fine head of hair? We covet, envy, and even worship a great head of hair..My late great mother, (lung cancer, not from cigarettes, bad but too much casino air, Atlantic CIty, New Jersey) in hospice, on the day before she passed, woke from her morphine induced “sleep”, looked around at us sitting by her bedside, and asked, “How’s my hair?” Her final words. (True, story. To be fair, Mom was always a Jackie Kennedy, never Onassis, wannabe.) Millions aren’t so lucky. In the United States, by age 60, 65% of men, and 80% of women have noticeable hair loss. In total 56 million men and women experience hair loss.(2)
To understand hair loss and what can be done to correct it, we must understand the natural growth, and demise, of a single hair follicle. Hair growth takes place in four phases:(4)
1. ACTIVE GROWTH (ANAGEN) PHASE The active growth phase lasting two to six years. Hair grows 18 to 24 inches before entering into the transitional phase. 80-90% of all hair follicles are in this growth phase on a healthy head. 2. TRANSITIONAL (CATAGEN) PHASE The shortest of the hair cycles lasting one to two weeks occurs when the lower third of the hair follicle is cut off from its blood supply. The hair itself shrinks to 1/6 its expected length. Catagen hair accounts for 2-3% of all follicles at any one time. 3. RESTING PHASE (TELOGEN) PHASE The dormant stage lasting one to four months. 10-15% of all hairs are in the Telogen phase. Telogen hair sheds or is pushed out by new hair follicles as the cycle renews. Ideally only 10-15% of hairs are telogenic. When more than 20% of hair are in this “resting” phase, noticeable thinning occurs. 4. SHEDDING PHASE (EXOGEN) PHASE Hairs in this phase shed easily as the follicles are preparing to return to the Anagen phase.
Types of Hair Loss (5) 1. TELOGEN EFFLUVIUM An abnormally high percentage of hair in the Telogen phase results in an overall thinning of hair. Common causes of this type of hair loss include chronic stress, toxins, fungal infections, nutritional deficiencies, and hormonal imbalances. 2. ANDROGENETIC ALOPECIA “Male-pattern” baldness is not limited to men. In women, the hair thins at the crown or widens in the part. The hair thins revealing a bare scalp. 3. ALOPECIA AREATA Presents as patches of lost hair. Alopecia Areata is usually an autoimmun condition with an association of nail issues also. 4. MISCELLANEOUS TYPES a. Traction from braids, weaves or wigs b. Chemotherapy-Related Hair Loss c. Frontal Fibrosing Alopecia (FFA) d. Lichen Planopilaris (LPP) Etiology of Hair Loss (6) 1. Sub-Optimal Thyroid Function The thyroid is the body’s “gas pedal,” determining how fast, or slow all bodily functions operate. When slowed due to inadequate “fuel,” namely usable thyroid substrate, the oils, fluids and tissues, especially the hair follicles function inadequately. The hair follicles spend an abnormal amount of time, and hence an abnormal number of hair follicles are in the Telogen or resting phase, resulting in a form of Telogen Effluvium. 2. Nutritional Deficiencies Nutritional deficiencies, specifically silica and zinc leads to hair loss. Micronutrient testing is indicated when this is suspected. 3. Stress In 1881, George Miller Beard, M.D., a neurologist and graduate from the New York College of Physicians and Surgeons, described a condition based on excess “nervous energy.” Constant over stimulation of the nervous system from the fast paced American lifestyle resulted in “neurasthenia,” burnout, or nervous exhaustion.
Symptoms of neurasthenia included nervous dyspepsia, insomnia, hysteria, hypochondria, asthma, sick-headache, skin rashes, hay fever, premature baldness, inebriety, hot and cold flashes, nervous exhaustion, brain-collapse, and forms of ‘elementary insanity. The best educated and most sophisticated Americans were the most afflicted. Theodore Roosevelt and Frederic Remington were two prominent figures of their day suffering from “neurasthenia.”
The “cure” was a withdrawal from the modern life, rest and a less hectic lifestyle. Critics countered that urban life in the late nineteenth century had produced a “pathetic, pampered, physically and morally enfeebled 97 pound weaklings, unworthy successors to the stalwart Americans who had fought the Civil War and tamed a continent.”.(7)
Physicians pigeonholed patients into this “nervous energy” category, relieving themselves of more vigilant diagnosis. Early signs of tuberculosis, heart failure and epilepsy were chalked up to neurasthenia and when later discovered to be in error, gave fuel to those who saw this “malady,” as a sham. The term neurasthenia is no longer used to describe any medical condition, but the conditions that lead to its “discovery,” diagnosis and its’ symptoms are remarkably similar to a hormonal condition with distinct diagnostic criteria known as “Adrenal Fatigue.”
The adrenal glands, pea sized organs, sit on top of the kidneys. They produce hormones that regulate blood pressure, electrolytes balance, blood sugar, immune responses, digestion, and stress responses. In regards to the latter, constant unremitting stress, as experienced by nearly everyone in today’s society, hijacks normal hormonal responses, redeploying the adrenals’ resources, in the form of the hormone cortisol, to combat the “evil” of the moment. The other adrenal functions, digestion, immune response, and thyroid hormone production, are temporarily put on hold or slowed until the stress has passed.
Cortisol is our protector. It lies in wait, like the lineup of computer programs opened at startup and running in the background, ready at an instant, when needed, to spring into action. In an ideal world, the stressor passes quickly and the adrenals resume lurking behind the scene awaiting the next crisis. In our non-ideal world, one stress begets a second stress, which begets a third stress, ad infinitum, putting the adrenal gland into permanent overdrive. The body is flooded with cortisol driving the adrenals to handle the stress but eventually it cannot keep up. The result is adrenal “burnout” or fatigue.
The thyroid is exquisitely impacted by the constant flooding and eventual depletion of cortisol. High levels signal the brain to lower the production of stressor hormones. Unfortunately, thyroid hormone is produced in the same pathway and is unwittingly lowered. Recall the critical step of converting T4 to the usable thyroid hormone free T3. Stress hormones affect the enzymes that convert T4 to T3 converting T4 into an inert unusable reverse T3.
Chronically elevated cortisol levels release inflammatory cells which desensitizes thyroid receptors to thyroid hormone. Like diabetics who don’t respond to insulin, adequate thyroid hormone may exist, but the result is inadequate thyroid utilization.
Increased circulatory cortisol increases estrogen in the blood stream. Estrogen increases thyroid binding globulin, tying up T3 and T4, reducing hormone levels to achieve the conversion to free T3. Elevated cortisol levels with its’ inherent state of chronic inflammation can trigger “leaky gut syndrome,” latent infections leading and autoimmune diseases.
Hair follicles accumulate in the resting (Telogen) phase.
4. Sex Hormone Imbalances Male: Excess testosterone metabolizes into dihydrotestosterone (DHT) and estradiol. DHT attaches to hair follicles, effectively strangling them causing “organ” death. The key to preventing, slowing, or possibly reversing the effects of DHT is by inhibiting this conversion of Testosterone into DHT. (Essentially the mechanism of action of hair loss products such as Rogaine.)
Type 2 5alpha reductase is the enzyme that that converts testosterone into DHT. Type 2 5alpha reductase is primarily found in the hair follicles and the prostate gland.
The conversion of too much testosterone to DHT results in androgenetic alopecia. As a man ages he retains estrogen and converts testosterone into estrogen at a higher rate. The result is 1+1=4, the 4 being excess DHT as a result of excess estrogen.
Women: Estrogen dominance is the culprit in women. Child birth, birth control medications, stress, toxins, along with entrance into the perimenopausal arena, creates an estrogen dominant pattern. Estrogen signals the liver to produce inordinate amounts of Thyroid Binding Globulin (TBG). T4, the “storage unit” of the thyroid must convert to T3, the hormone that the “work.” Excess TBG leads to an inability to convert T4 to T3, resulting in a relative hypothyroidism and Telogen Effluvium. Estrogen dominance results in excess DHT, leading to a female version of “male pattern” baldness. (8) Miscellaneous areas to explore if estrogen dominance is ruled out: Heredity, insulin resistance, polycystic ovarian syndrome and a low antioxidant state. (9)
5. Medications Causing Hair Loss (10) Antibiotics: gentamicin, chloramphenicol Anticoagulants: warfarin, heparin Antidepressants: fluoxetine, desipramine, lithium Anticonvulsants: valproic acid, phenytoin, carbamazepine Cardiovascular meds: ACE inhibitors, beta blockers Chemotherapy drugs: doxorubicin, vincristine, etoposide Endocrine drugs: bromocriptine, clomiphene, danazol Gout medications: colchicine, allopurinol Lipid lowering drugs: gemfibrozil, fenofibrate, cholestyramine, clofibrate NSAIDS: ibuprofen, indomethacin, naproxen Reflux/ulcer medications: cimetidine, ranitidine, famotidine Antithyroid drugs: iodine, PTU Retinoids: vitamin A overdose, isotretinoin 6. Trichotillomania- Repetitive hair pulling resulting in hair loss. Considered an OCD variant. Treatment usually includes behavioral therapies, SSRI’s or other drugs to treat OCD. Metabolic therapies include NAC, inositol, L-tryptophan, niacin and vitamin B6.
7. Scarring Alopecia- Resulting from burns, radiation, or other injuries or diseases. Destroys the dermis with permanent hair loss. Rx: Vitamin A 150,000 IU qd for 6 weeks stopped disease progression. Maintenance Rx: 150,000 IU qd for three 6 week periods every year. (11)
Conventional Therapies for Hair Loss (12)
Cyproterone acetate Minoxidil Flutamide Ketoconazole Finasteride Hair Transplantation Dutasteride Light Therapy, Botulinum Toxins Holistic Resolutions to Hair Loss
1. Proper Hypothyroidism Diagnosis & Treatment (13-14)
The thyroid functions as the body’s “gas pedal.” Like Goldilocks, we need it to be just right, not too little, not too much. The gland produces two major hormones, triiodothyronine (T3), the active hormone, and thyroxine (T4), the storage hormone. The thyroid also produces calcitonin, a hormone responsible for calcium balance and bone density and magnesium.
98% of all thyroid disorders results in hypothyroidism. Common symptoms include cold intolerance, unexplained weight gain, fatigue, thinning of the hair, the outer third of the eyebrow, the skin and the nails, increased body fat, energy loss, cognitive loss, memory loss, mood disorders, lowered body temperature (never greater than 97.6 F), fluid retention, and a poor sense of well-being.
When the underlying cause of hypothyroidism is the immune system, not the thyroid per se., and it is not addressed, the treatment will not be effective. 25 percent of patients with autoimmune, Hashimoto’s thyroiditis develop polyglandular syndromes (such as pernicious anemia, diabetes, or adrenal insufficiency) or other autoimmune diseases (such as Sjogren’s syndrome).
2. Key Supplements for Healthy Hair (15)
Biotin- Water-soluble B-vitamin found in green leafy vegetables. Regulates mitochondrial enzymes in hair follicles. Depleted by cigarette smoking, aging, excess alcohol, strenuous exercise, burn victims, shortened gut syndrome (GI resections), achlorhydria, and raw egg consumption. (16-17) Use orally or in essential oil mixture. Dose is 30-100 mcg/day.
Zinc -Promotes cell reproduction, tissue growth and repair of broken tissues. Maintains the oil-secreting glands attached to hair follicles. Study showed that 15 patients with alopecia areata received 45 mg of zinc TID. All had complete return of hair growth within 6 months. (18) Maintenance dose is 15 mg per day along with 1 mg copper as a balance.
N-Acetyl-Cysteine- Precursor to glutathione the most powerful antioxidant in the body. Protects DNA from chemical damage, detoxifies heavy metals, and it keeps arteries and airways open. It activates important functions of the immune system.
B Vitamins (B6, B12)- In the form of Pyridoxal 5-Phosphate (PLP), the B Vitamins act as catalysts to activate the enzymes and chemical reactions to commence the metabolism of keratin and melanin in the hair follicles. B vitamins control hormone release., regulating androgen interaction with hair metabolism. Testosterone breaks down into dihydrotestosterone (DHT). Elevated DHT levels diminishes hair growth by decreasing the length of the anagen, hair growth phase, and the follicle size. Vitamin B6 binds to the testosterone receptors, stopping DHT formation.
Niacin- Vitamin B3 converts carbohydrates into energy, delivers the energy to cells where needed and maintains cell integrity. Niacin is a vasodilator, hence the niacin “flush” so common when taken, “washes” carbohydrates through the body, reducing visceral fat and serum cholesterol. The flush can be minimized by taking niacin with a meal or starting (with a) low dose and gradually increasing its potency. The vasodilator effect of niacin delivers increased oxygen and nutrients to the hair follicle resulting in thicker hair.
Arginine- L-arginine, a precursor to nitrogen oxide, opens the potassium channels of the cell, improving blood supply to the hair root.
Lysine- An essential amino acid, lysine stimulates collagen and is necessary for restoring damaged hair. Food sources for lysine include fish (especially salmon, sardines and cod), dairy, poultry, red meat, pork, legumes, nuts, spirulina and pulses.
Saw Palmetto (for Men)- Prevents conversion of testosterone to DHT
Acetyl-L-Carnitine- Up regulates proliferation and down regulates apoptosis in hair follicle keratinocytes. Turns fat into energy. Acetyl-L Carnitine improves the membrane potential of the hair follicle which is significantly diminished along with potassium channel function within withering hair follicles.
Iron- A lack of iron results in a decrease in hemoglobin, the ingredient that carries oxygen for growth and repair of all cells including hair follicles. Iron deficiency states move hair follicles into a premature and prolonged telogen (resting) phase. Hair growth is a “non-essential” bodily function. It is one of the first systems to shut down in a state of iron deficiency. Hence, hair loss is an early warning sign of iron deficiency anemia.
Vitamin D- Essential for calcium homeostasis, immune regulation and cell growth. A host of autoimmune diseases, including alopecia areata, exhibit low levels of Vitamin D. The severity of serum 25(OH)D deficiency is inversely related to the severity of hair loss.
Gluten- Hair loss is an early sign of gluten intolerance. In all cases of alopecia or extensive hair loss, we recommend a strict gluten free diet for 4 weeks as a trial. (19)
Vitamin A- Hair loss is a symptom of Vitamin A toxicity especially in renal failure. Usually resolves when toxicity is addressed. (20)
Emu Oil- Contains linolenic acid a potent 5-alpha reductase inhibitor. Compound with virgin coconut oil to create an antibacterial, anti-inflammatory scalp treatment to DHT.
3. Adequate Protein Insufficient protein effects on your hair growth. The CDC recommends 46 to 56 grams of protein per tain to maintain hair growth. (21) Inadequate protein results in protein rationing by shutting down less important functions.
4. Iron When iron levels fall below 30 mg/L hair growth and regeneration are decreased. Iron deficiency commonly causes hair to be brittle and dry with narrowing or splitting of the hair shaft. Iron replacement restored hair growth in those whose sole issue was iron deficiency. (22-23)
5. GI Evaluation-The 4 R’s Depleted stomach acid leads to impaired protein digestion and decreased nutrient absorption. Disturbed GI flora leads to inadequate nutrient utilization. Pancreatic enzyme deficiency leads to malabsorption of essential fatty acids and zinc.
The “4 R’s” include: (24)
“Remove” inflammatory foods such as gluten, dairy, corn, soy, eggs and sugar. Eliminate gastric irritants like alcohol, caffeine or drugs. Infections, even low grade infections need to be treated with herbs, antiparasitic and antifungal medication, anti-fungal supplements and antibiotics when appropriate.
“Replace” essential nutrients for proper utilization of foodstuffs. Digestive enzymes, hydrochloric acid and bile salts are needed for proper digestion. “Restore ” normal GI flora. Probiotics containing bifidobacteria and lactobacillus
dosed from 25 to 100 billion units a day along with prebiotics and fiber.
“Repair, ” L-glutamine along with zinc, omega 3 fish oil, vitamins A, C, E, slippery elm and aloe vera containing supplements rebuilds the damaged intestinal wall.
Addressing Stress & Adrenal Fatigue Diagnosis: The HPA AXIS Stress Index Panel . A four point saliva test performed in a single day. Normal are high upon awakening and then quickly fall and flatten out by noon.
Treatment begins with reducing stress (easier said than). Proper diet, yoga, Pilates, Qi Gong, meditation, massage and infra red sauna are a few techniques used to successfully control stress. For some a complete lifestyle change may be the only way to better health. Supplements that enhance the adrenal glands include the adaptogenic herbs Rhodiola, Ginseng, and cordyceps , Pregnenolone, DHEA (cortisol precursors), 5 HTP (for sleep, well-being and mood regulation), adrenal glandulars (to balance cortisol and replenish the catecholamines dopamine, norepinephrine, and epinephrine), and if still no relief Cortef (low dose cortisone). 6. Male Hormones and Hair Loss: Natural DHT Blockers Saw Palmetto- Inhibits 5-alpha-reductase. 240-260 mg @ bedtime minimum. (25) Progesterone- “anti-feminizing in men.” Prevents excess conversion of testosterone to estrogen in males by blocking type 2 5alpha reductase. Nettle Root- Can be used topically with Coconut or Olive Oil and Rosemary extract as a shampoo. Pygeum- Inhibits DHT. Commonly used in combination with Saw Palmetto Rosemary Oil- Inhibits DHT. Use as scalp massage Pumpkin Seed Oil- Inhibits DHT. Can mix with apple cider vinegar as salad dressing.
7. Female Hormones and Hair Loss Proper balancing of bioidentical, not synthetic, progesterone to estrogen, will in many cases resolve hair loss. Fix the cause. 8. Alkalinize the Body Maximal DHT conversion occurs when the pH of the body is between 5.0 and 5.5. This corresponds to what is achieved by following the Standard American Diet. (S.A.D.) Alkalinizing the body prevents DHT from binding to hair follicles enabling them to thrive. A liver Detox such as Dr. Clearfield’s Ultimate Paleocleanse will restore scalp pH to at least 7 in two weeks. If the alkaline environment is maintained, hair will regrow, stronger and thicker than before.. Below is a food chart comparing the relative acidity or alkalinity of different food groups to one another. It is evident that the “normal” American sets him or herself up for failure by consuming highly acidic foods.
9. Delayed Food Allergies Do’s: Bone Broth- Helps restore gut barrier (i.e. heals the “leaky gut”) Fermented Vegetables and Beverages (i.e. sauerkraut, kimchi, beet kvass, coconut water kefir, etc.). High in Probiotics Fish and Shellfish- High in omega-3 fats. Eat at least one pound of cold-water, fatty fish per week EPA and DHA needs. Organ Meats- Loaded micronutrients that promote healthy immune function. Micronutrients Vitamins A & D : Immune enhancement. Vitamin D supports proper T-regulatory cell function. Cod liver oil is the best source of A & D. Iodine & Selenium – Crucial for immune health and successful conversion of T4 to T3. Glutathione : Promotes healthy function of T regulatory cells Niacin (B3), Pyridoxine (B6), Vitamin C, Magnesium, Iron, Copper, Zinc, and Manganese . Eliminate Gluten Soy Dairy Eggs Corn Saturated and/or trans fats Processed foods Sugar Substitute For: Salt: Powdered garlic, powdered onion, lemon juice, lime juice, lemon crystals, turmeric, ground cloves, oregano, ground allspice, celery seeds, coriander seeds, ground cardamom seeds Butter/Fat: Olive oil, coconut oil, flaxseed oil, ghee Sugar: Obtain sugar primarily from fruits and vegetables, not concentrated sources. Fruit purees flavored with lemon juice and spices (cinnamon, nutmeg, mint leaves, ginger, vanilla), Stevia, Xylitol in limited quantities. Alcohol :Limited to an occasional glass of wine, beer or spirits. Red wine contains a number of health promoting phytochemicals and antioxidants. Cereals : Nut flours (almond, pecan, walnut, hazelnut, etc.) can be made in a food processor Cheese: Nut cheeses (cashew, dairy, soy free) Milk: Almond milk, coconut milk Protein: Ancient Nutrition Protein Bone Broth Goitrogens (27) In small amounts goitrogens increase the need for iodine. In large quantities they can damage the thyroid. Goitrogens should be limited to 3-6 servings per week. Steaming can reduce the danger by ⅓ and thoroughly cooking them and discarding the water in case of boiling decreases the harm by 90%.
Cruciferous Vegetables C Others Bok Choy Broccoli Brussel Sprouts Cabbage Canola Cauliflower Chinese Cabbage Collard Greens Horseradish Kale Kohlrabi Mustard Greens Radishes Rutabaga Turnips Soy Pine Nuts, Peanuts Millet Strawberries Pears, Peaches Bamboo Shoots Spinach Sweet Potatoes
10. Compounded Formulas
a. Compounded Caffeine Formula (28) i. Caffeine 0.001% to 0.005% in VersaBase shampoo #4 oz (120cc) ii. Shampoo scalp. Leave on 15 minutes and wash off. Repeat daily. b. Zinc pyrithione 1% in topical solution with or without minoxidil 10%. 4oz (29) i. Sig: apply to hair follicles qhs. Cover with shower cap and leave on all night. Wash out in the am. c. Melatonin 1m/mL in VersaBase Shampoo #4őz. (120cc) (30) i. Sig: shampoo daily. Leave on for 10 minutes and then wash off. d. Minoxidil 8.5%/Finasteride 0.1% scalp solution #2 oz. (31) i. Sig: apply to hair follicles qhs. Cover with shower cap and leave on all night. Wash out in the am. 11. New Trends Platelet Rich Plasma Platelet-rich plasma (PRP) is created by collecting blood from the patient and spinning it in a centrifuge to separate the platelets from the blood. After applying local anesthetics to the scalp, PRP is combined with an FDA approved biomatrix (Acell) and nutrients, then either injected or via a micro-needling device, or applied to localized areas such as the eyebrows or beard, or the full scalp. PRP contains many growth factors to stimulate the hair follicle restoration. It stimulates inactive or newly implanted hair follicles into an active growth phase. Following up with progesterone or a melatonin based scalp treatment enhances the process. New hair sprouts as early as 2 months. 4-8 months is the typical time frame for hair to thicken and become noticeable. Additional injections may be necessary every 2 years. Recovery time is minimal and pain is usually managed with over the counter ibuprofen or homeopathic remedies such as Arnica Montana and/or Boswellia. “Hair loss reduced and at 3 months it reached normal levels. Hair density reached a peak at 3 months. At 6 months and at 1 year, it was significantly increased, 156.25 ± 37.75 (P < 0.001) and 153.70 ± 39.92 (P < 0.001) respectively, comparing to baseline. Patients
were satisfied with a mean result rating of 7.1 on a scale of 1-10. No remarkable adverse effects were noted.” (32) “A mean increase of 33.6 hairs in the target area and a mean increase in total hair density of 45.9 hairs per cm² compared with baseline values. No side effects were noted during treatment. The data clearly highlight the positive effects of PRP injections on male pattern hair loss and absence of major side effects.” (33) “PRP was found to increase hair regrowth significantly and to decrease hair dystrophy and burning or itching sensation compared with TrA or placebo. Ki-67 levels, which served as markers for cell proliferation, were significantly higher with PRP. No side-effects were noted during treatment.” (34) No Stitch Transplant As advertised, no stitches and no staples. There is little-to-no discomfort (no scalpel involved). Patients resume normal activity after only a few days. The hair line is natural looking with no linear scar. Low Level Laser Therapy Laser light, specifically the red visible wavelengths target tissue molecules. The energy level of the molecules increases and the molecules respond by “working off” the excess energy with adaptive changes. In the case of hair follicles this adaptive change is the stimulation of new, thicker follicular growth. Conclusion Hair loss is as simple as hereditary or an early warning sign of a serious health condition. While, at present, surgical transplant is the only way to overcome Dad’s chrome dome, infections, autoimmune issues, scarring, inadequate protein and essential vitamin deficiencies, medications and stress also plays a role. Proper treatment demands we search for the underlying cause. Call us at 775-359-1222 or email [email protected] to find your answers.
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Dr. William Clearfield
Address : 9550 S McCarran Blvd b, Reno, NV 89523 Phone : 775-359-1222 Fax : 888-977-3503 Email : [email protected] Website : drclearfield.net
References 1. http://ift.tt/2xqUcsS 2. Rogers, N., et al., “Medical treatments for male and female pattern hair loss,” Jour Amer Acad Derm 2008; 59(4):547-66. 3. http://ift.tt/2xYvhZ4 wth-cycle.jpg&imgrefurl=http%3A%2F%2Fwww.oblique.co.nz%2Fhair_health%2Fhairstructure.html&docid=Qa VBvcatbRCqpM&tbnid=4BJnp5uQ83LuVM%3A&vet=10ahUKEwiqvsWW_6DVAhWm7oMKHXpgAgYQMwgqK AMwAw..i&w=400&h=178&bih=635&biw=1351&q=life%20cycle%20of%20a%20hair%20follicle&ved=0ahUKEwi qvsWW_6DVAhWm7oMKHXpgAgYQMwgqKAMwAw&iact=mrc&uact=8 4. K. S. Stenn & R. Paus (1 January 2001). “Controls of Hair Follicle Cycling”. Physiological Reviews. 81 (1): 449–494. PMID 11152763. 5. http://ift.tt/2z75wru 6. http://ift.tt/1H7sk92 7. The Birth of Modern Culture, Digital History, http://ift.tt/2z7ED6S, accessed September 7, 2015. 8. http://ift.tt/2xqUdwW 9. Murray, M., et al., Hair Loss in Women. In Pizzorno, J., and Murray, M., Textbook of Natural Medicine St. Louis: Elsevier/Churchill Livingstone, 2013, p. 1406-08 10. Mounsey., A., et al., “Diagnosing and treating hair loss,” Amer Fam Physician 2009; 80(4):356-62. 11. Kalz, F., “Cicatricial alopecia and vitamin A,” Arch Dermatol 1958; 78:740-43. 12. Mesinkovska, N., et al., “Hair: what is new in diagnosis and management? Female pattern hair loss update,” Dermatol Clin 2013; 31(1):119-27. 13. Rothenberg, Ron, Thyroid Optimization, BHRT Syllabus, A4M Lecture Series, Los Angeles, CA, February 26, 2015, p. 62. 14. Clearfield, W., Patient Mysteries; Are You Thyroid Deficient, Healthy Beginning Magazine, August 31, 2015,
Patient Mysteries: Are you thyroid deficient?
15. http://ift.tt/2yBWiWA or-healthy-hair-skin-and-nails#d89PpsjmUPybGAjQ.97 16. Krause, K., et al., “Vitamin status in patients on chronic anticonvulsant therapy,” Int Jour Vitamin Nutri Res 1982; 5294):375-85. 17. Mock, D., et al., “Biotin catabolism is accelerated in adults receiving long-term therapy with anticonvulsants,” Neurology 1997; 49:1444-47. 18. Wolowa, F., et al., “Zinc sulfate in the treatment of alopecia areata,” (Article in Polish) Przeg Derm 1978; 65:687-96. 19. Murray, M., et al., Hair Loss in Women. In Pizzorno, J., and Murray, M., Textbook of Natural Medicine. St. Louis: Elsevier/Churchill Livingstone, 2013, p. 1406-08. 20. Shmunes, E., “Hypervitaminosis A in a patient with alopecia receiving renal dialysis,” Arch Dermatol 1979; 115:882-83. 21. McKenzie, D, How Much Protein to Prevent Hair Loss, http://ift.tt/2z75y2A November 18, 2015. 22. Moeinvaziri, M., et al., “Iron status in diffuse telogen hair loss among women,” Acta Dermatovenerol Croat 2009; 17(4):279-84. 23. Hard, G., “Non-anemic iron deficiency as an etiologic factor in diffuse loss of hair of the scalp in women,” Acta Derm Venereol 1963; 43:562-69. 24. Reasoner, J., LeakyGut Syndrome in Plain English – and How to Fix It, http://ift.tt/1LYkCkQ, Accessed September 6, 2015 25. Prager, N., et al., “A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5- alpha-reductase in the treatment of androgenic alopecia,” Jour Altern Complement Med 2002;8:143-52. 26. http://ift.tt/2yHL5mT mtDWQAKVYoAl-ZwxINw 27. Kresser, C. Clinician’s Guide to Thyroid Disease, Kresser Institute;2016:5-6 28. Bussoletti, C., et al., “Use of a cosmetic caffeine lotion in the treatment of male androgenetic alopecia,” Jour of Applied Cosmetology 2011; 29(4):167-79. 29. Berger, R., et al., “The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial,” Brit Jour Dermatol 2003; 149(2):354-62. 30. Fischer, T., et al., “Melatonin increases antagen hair rate in women with androgenetic alopecia or diffuse alopecia: results of a pilot randomized controlled trial,” Brit Jour Dermatol 2004; 150:341-45. 31. A4M Module XIV; Module XXIV: The Nuts and Bolts of Writing Prescriptions for Compounded Medications:The Ultimate in Personalized Medicine: Del Ray Beach, Florida, June 24-26, 2014 32. Maria-Angeliki Gkini, Alexandros-Efstratios Kouskoukis, Gregory Tripsianis,1 Dimitris Rigopoulos,2 and Konstantinos Kouskoukis, Study of Platelet-Rich Plasma Injections in the Treatment of Androgenetic Alopecia Through an One-Year Period, J Cutan Aesthet Surg. 2014 Oct-Dec; 7(4): 213–219. doi: 10.4103/0974-2077.150743 33. Gentile P1, Garcovich S2, Bielli A3, Scioli MG3, Orlandi A3, Cervelli V4., The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial. Stem Cells Transl Med. 2015 Nov;4(11):1317-23. doi: 10.5966/sctm.2015-0107. Epub 2015 Sep 23. 34. Trink A1, Sorbellini E, Bezzola P, Rodella L, Rezzani R, Ramot Y, Rinaldi F., A randomized, double-blind, placebo- and active-controlled, half-head study to evaluate the effects of platelet-rich plasma on alopecia areata. Br J Dermatol. 2013 Sep;169(3):690-4. doi: 10.1111/bjd.12397.
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Hair Restoration Project | Dr William Clearfield Reno
Hair Restoration Project | Dr William Clearfield Reno
The Hair Restoration Project PRP technique can treat male and female pattern hair loss, alopecia areata, and eyebrow hypotrichosis
Below there is a lot about thinning hair in Reno…I mean a lot of information. More than you need but it is important that you have the option of knowing everything there is to know about male and female pattern baldness and hair loss treatments in Reno NV. This article is about understanding hair loss and how and why your thinning hair and baldness pattern can be replaced without surgery.
Contact Dr. William Clearfield at the Clearfield Medical Group to schedule your consultation to see if the Hair Restoration Project is right for your male or female pattern baldness. 1-775-359-1222 and go to your website www.drclearfield.net
More information on the “Hair Restoration Project” go to http://ift.tt/2yHJH3y
Who doesn’t admire a fine head of hair? We covet, envy, and even worship a great head of hair..My late great mother, (lung cancer, not from cigarettes, bad but too much casino air, Atlantic CIty, New Jersey) in hospice, on the day before she passed, woke from her morphine induced “sleep”, looked around at us sitting by her bedside, and asked, “How’s my hair?” Her final words. (True, story. To be fair, Mom was always a Jackie Kennedy, never Onassis, wannabe.) Millions aren’t so lucky. In the United States, by age 60, 65% of men, and 80% of women have noticeable hair loss. In total 56 million men and women experience hair loss.(2)
To understand hair loss and what can be done to correct it, we must understand the natural growth, and demise, of a single hair follicle. Hair growth takes place in four phases:(4)
1. ACTIVE GROWTH (ANAGEN) PHASE The active growth phase lasting two to six years. Hair grows 18 to 24 inches before entering into the transitional phase. 80-90% of all hair follicles are in this growth phase on a healthy head. 2. TRANSITIONAL (CATAGEN) PHASE The shortest of the hair cycles lasting one to two weeks occurs when the lower third of the hair follicle is cut off from its blood supply. The hair itself shrinks to 1/6 its expected length. Catagen hair accounts for 2-3% of all follicles at any one time. 3. RESTING PHASE (TELOGEN) PHASE The dormant stage lasting one to four months. 10-15% of all hairs are in the Telogen phase. Telogen hair sheds or is pushed out by new hair follicles as the cycle renews. Ideally only 10-15% of hairs are telogenic. When more than 20% of hair are in this “resting” phase, noticeable thinning occurs. 4. SHEDDING PHASE (EXOGEN) PHASE Hairs in this phase shed easily as the follicles are preparing to return to the Anagen phase.
Types of Hair Loss (5) 1. TELOGEN EFFLUVIUM An abnormally high percentage of hair in the Telogen phase results in an overall thinning of hair. Common causes of this type of hair loss include chronic stress, toxins, fungal infections, nutritional deficiencies, and hormonal imbalances. 2. ANDROGENETIC ALOPECIA “Male-pattern” baldness is not limited to men. In women, the hair thins at the crown or widens in the part. The hair thins revealing a bare scalp. 3. ALOPECIA AREATA Presents as patches of lost hair. Alopecia Areata is usually an autoimmun condition with an association of nail issues also. 4. MISCELLANEOUS TYPES a. Traction from braids, weaves or wigs b. Chemotherapy-Related Hair Loss c. Frontal Fibrosing Alopecia (FFA) d. Lichen Planopilaris (LPP) Etiology of Hair Loss (6) 1. Sub-Optimal Thyroid Function The thyroid is the body’s “gas pedal,” determining how fast, or slow all bodily functions operate. When slowed due to inadequate “fuel,” namely usable thyroid substrate, the oils, fluids and tissues, especially the hair follicles function inadequately. The hair follicles spend an abnormal amount of time, and hence an abnormal number of hair follicles are in the Telogen or resting phase, resulting in a form of Telogen Effluvium. 2. Nutritional Deficiencies Nutritional deficiencies, specifically silica and zinc leads to hair loss. Micronutrient testing is indicated when this is suspected. 3. Stress In 1881, George Miller Beard, M.D., a neurologist and graduate from the New York College of Physicians and Surgeons, described a condition based on excess “nervous energy.” Constant over stimulation of the nervous system from the fast paced American lifestyle resulted in “neurasthenia,” burnout, or nervous exhaustion.
Symptoms of neurasthenia included nervous dyspepsia, insomnia, hysteria, hypochondria, asthma, sick-headache, skin rashes, hay fever, premature baldness, inebriety, hot and cold flashes, nervous exhaustion, brain-collapse, and forms of ‘elementary insanity. The best educated and most sophisticated Americans were the most afflicted. Theodore Roosevelt and Frederic Remington were two prominent figures of their day suffering from “neurasthenia.”
The “cure” was a withdrawal from the modern life, rest and a less hectic lifestyle. Critics countered that urban life in the late nineteenth century had produced a “pathetic, pampered, physically and morally enfeebled 97 pound weaklings, unworthy successors to the stalwart Americans who had fought the Civil War and tamed a continent.”.(7)
Physicians pigeonholed patients into this “nervous energy” category, relieving themselves of more vigilant diagnosis. Early signs of tuberculosis, heart failure and epilepsy were chalked up to neurasthenia and when later discovered to be in error, gave fuel to those who saw this “malady,” as a sham. The term neurasthenia is no longer used to describe any medical condition, but the conditions that lead to its “discovery,” diagnosis and its’ symptoms are remarkably similar to a hormonal condition with distinct diagnostic criteria known as “Adrenal Fatigue.”
The adrenal glands, pea sized organs, sit on top of the kidneys. They produce hormones that regulate blood pressure, electrolytes balance, blood sugar, immune responses, digestion, and stress responses. In regards to the latter, constant unremitting stress, as experienced by nearly everyone in today’s society, hijacks normal hormonal responses, redeploying the adrenals’ resources, in the form of the hormone cortisol, to combat the “evil” of the moment. The other adrenal functions, digestion, immune response, and thyroid hormone production, are temporarily put on hold or slowed until the stress has passed.
Cortisol is our protector. It lies in wait, like the lineup of computer programs opened at startup and running in the background, ready at an instant, when needed, to spring into action. In an ideal world, the stressor passes quickly and the adrenals resume lurking behind the scene awaiting the next crisis. In our non-ideal world, one stress begets a second stress, which begets a third stress, ad infinitum, putting the adrenal gland into permanent overdrive. The body is flooded with cortisol driving the adrenals to handle the stress but eventually it cannot keep up. The result is adrenal “burnout” or fatigue.
The thyroid is exquisitely impacted by the constant flooding and eventual depletion of cortisol. High levels signal the brain to lower the production of stressor hormones. Unfortunately, thyroid hormone is produced in the same pathway and is unwittingly lowered. Recall the critical step of converting T4 to the usable thyroid hormone free T3. Stress hormones affect the enzymes that convert T4 to T3 converting T4 into an inert unusable reverse T3.
Chronically elevated cortisol levels release inflammatory cells which desensitizes thyroid receptors to thyroid hormone. Like diabetics who don’t respond to insulin, adequate thyroid hormone may exist, but the result is inadequate thyroid utilization.
Increased circulatory cortisol increases estrogen in the blood stream. Estrogen increases thyroid binding globulin, tying up T3 and T4, reducing hormone levels to achieve the conversion to free T3. Elevated cortisol levels with its’ inherent state of chronic inflammation can trigger “leaky gut syndrome,” latent infections leading and autoimmune diseases.
Hair follicles accumulate in the resting (Telogen) phase.
4. Sex Hormone Imbalances Male: Excess testosterone metabolizes into dihydrotestosterone (DHT) and estradiol. DHT attaches to hair follicles, effectively strangling them causing “organ” death. The key to preventing, slowing, or possibly reversing the effects of DHT is by inhibiting this conversion of Testosterone into DHT. (Essentially the mechanism of action of hair loss products such as Rogaine.)
Type 2 5alpha reductase is the enzyme that that converts testosterone into DHT. Type 2 5alpha reductase is primarily found in the hair follicles and the prostate gland.
The conversion of too much testosterone to DHT results in androgenetic alopecia. As a man ages he retains estrogen and converts testosterone into estrogen at a higher rate. The result is 1+1=4, the 4 being excess DHT as a result of excess estrogen.
Women: Estrogen dominance is the culprit in women. Child birth, birth control medications, stress, toxins, along with entrance into the perimenopausal arena, creates an estrogen dominant pattern. Estrogen signals the liver to produce inordinate amounts of Thyroid Binding Globulin (TBG). T4, the “storage unit” of the thyroid must convert to T3, the hormone that the “work.” Excess TBG leads to an inability to convert T4 to T3, resulting in a relative hypothyroidism and Telogen Effluvium. Estrogen dominance results in excess DHT, leading to a female version of “male pattern” baldness. (8) Miscellaneous areas to explore if estrogen dominance is ruled out: Heredity, insulin resistance, polycystic ovarian syndrome and a low antioxidant state. (9)
5. Medications Causing Hair Loss (10) Antibiotics: gentamicin, chloramphenicol Anticoagulants: warfarin, heparin Antidepressants: fluoxetine, desipramine, lithium Anticonvulsants: valproic acid, phenytoin, carbamazepine Cardiovascular meds: ACE inhibitors, beta blockers Chemotherapy drugs: doxorubicin, vincristine, etoposide Endocrine drugs: bromocriptine, clomiphene, danazol Gout medications: colchicine, allopurinol Lipid lowering drugs: gemfibrozil, fenofibrate, cholestyramine, clofibrate NSAIDS: ibuprofen, indomethacin, naproxen Reflux/ulcer medications: cimetidine, ranitidine, famotidine Antithyroid drugs: iodine, PTU Retinoids: vitamin A overdose, isotretinoin 6. Trichotillomania- Repetitive hair pulling resulting in hair loss. Considered an OCD variant. Treatment usually includes behavioral therapies, SSRI’s or other drugs to treat OCD. Metabolic therapies include NAC, inositol, L-tryptophan, niacin and vitamin B6.
7. Scarring Alopecia- Resulting from burns, radiation, or other injuries or diseases. Destroys the dermis with permanent hair loss. Rx: Vitamin A 150,000 IU qd for 6 weeks stopped disease progression. Maintenance Rx: 150,000 IU qd for three 6 week periods every year. (11)
Conventional Therapies for Hair Loss (12)
Cyproterone acetate Minoxidil Flutamide Ketoconazole Finasteride Hair Transplantation Dutasteride Light Therapy, Botulinum Toxins Holistic Resolutions to Hair Loss
1. Proper Hypothyroidism Diagnosis & Treatment (13-14)
The thyroid functions as the body’s “gas pedal.” Like Goldilocks, we need it to be just right, not too little, not too much. The gland produces two major hormones, triiodothyronine (T3), the active hormone, and thyroxine (T4), the storage hormone. The thyroid also produces calcitonin, a hormone responsible for calcium balance and bone density and magnesium.
98% of all thyroid disorders results in hypothyroidism. Common symptoms include cold intolerance, unexplained weight gain, fatigue, thinning of the hair, the outer third of the eyebrow, the skin and the nails, increased body fat, energy loss, cognitive loss, memory loss, mood disorders, lowered body temperature (never greater than 97.6 F), fluid retention, and a poor sense of well-being.
When the underlying cause of hypothyroidism is the immune system, not the thyroid per se., and it is not addressed, the treatment will not be effective. 25 percent of patients with autoimmune, Hashimoto’s thyroiditis develop polyglandular syndromes (such as pernicious anemia, diabetes, or adrenal insufficiency) or other autoimmune diseases (such as Sjogren’s syndrome).
2. Key Supplements for Healthy Hair (15)
Biotin- Water-soluble B-vitamin found in green leafy vegetables. Regulates mitochondrial enzymes in hair follicles. Depleted by cigarette smoking, aging, excess alcohol, strenuous exercise, burn victims, shortened gut syndrome (GI resections), achlorhydria, and raw egg consumption. (16-17) Use orally or in essential oil mixture. Dose is 30-100 mcg/day.
Zinc -Promotes cell reproduction, tissue growth and repair of broken tissues. Maintains the oil-secreting glands attached to hair follicles. Study showed that 15 patients with alopecia areata received 45 mg of zinc TID. All had complete return of hair growth within 6 months. (18) Maintenance dose is 15 mg per day along with 1 mg copper as a balance.
N-Acetyl-Cysteine- Precursor to glutathione the most powerful antioxidant in the body. Protects DNA from chemical damage, detoxifies heavy metals, and it keeps arteries and airways open. It activates important functions of the immune system.
B Vitamins (B6, B12)- In the form of Pyridoxal 5-Phosphate (PLP), the B Vitamins act as catalysts to activate the enzymes and chemical reactions to commence the metabolism of keratin and melanin in the hair follicles. B vitamins control hormone release., regulating androgen interaction with hair metabolism. Testosterone breaks down into dihydrotestosterone (DHT). Elevated DHT levels diminishes hair growth by decreasing the length of the anagen, hair growth phase, and the follicle size. Vitamin B6 binds to the testosterone receptors, stopping DHT formation.
Niacin- Vitamin B3 converts carbohydrates into energy, delivers the energy to cells where needed and maintains cell integrity. Niacin is a vasodilator, hence the niacin “flush” so common when taken, “washes” carbohydrates through the body, reducing visceral fat and serum cholesterol. The flush can be minimized by taking niacin with a meal or starting (with a) low dose and gradually increasing its potency. The vasodilator effect of niacin delivers increased oxygen and nutrients to the hair follicle resulting in thicker hair.
Arginine- L-arginine, a precursor to nitrogen oxide, opens the potassium channels of the cell, improving blood supply to the hair root.
Lysine- An essential amino acid, lysine stimulates collagen and is necessary for restoring damaged hair. Food sources for lysine include fish (especially salmon, sardines and cod), dairy, poultry, red meat, pork, legumes, nuts, spirulina and pulses.
Saw Palmetto (for Men)- Prevents conversion of testosterone to DHT
Acetyl-L-Carnitine- Up regulates proliferation and down regulates apoptosis in hair follicle keratinocytes. Turns fat into energy. Acetyl-L Carnitine improves the membrane potential of the hair follicle which is significantly diminished along with potassium channel function within withering hair follicles.
Iron- A lack of iron results in a decrease in hemoglobin, the ingredient that carries oxygen for growth and repair of all cells including hair follicles. Iron deficiency states move hair follicles into a premature and prolonged telogen (resting) phase. Hair growth is a “non-essential” bodily function. It is one of the first systems to shut down in a state of iron deficiency. Hence, hair loss is an early warning sign of iron deficiency anemia.
Vitamin D- Essential for calcium homeostasis, immune regulation and cell growth. A host of autoimmune diseases, including alopecia areata, exhibit low levels of Vitamin D. The severity of serum 25(OH)D deficiency is inversely related to the severity of hair loss.
Gluten- Hair loss is an early sign of gluten intolerance. In all cases of alopecia or extensive hair loss, we recommend a strict gluten free diet for 4 weeks as a trial. (19)
Vitamin A- Hair loss is a symptom of Vitamin A toxicity especially in renal failure. Usually resolves when toxicity is addressed. (20)
Emu Oil- Contains linolenic acid a potent 5-alpha reductase inhibitor. Compound with virgin coconut oil to create an antibacterial, anti-inflammatory scalp treatment to DHT.
3. Adequate Protein Insufficient protein effects on your hair growth. The CDC recommends 46 to 56 grams of protein per tain to maintain hair growth. (21) Inadequate protein results in protein rationing by shutting down less important functions.
4. Iron When iron levels fall below 30 mg/L hair growth and regeneration are decreased. Iron deficiency commonly causes hair to be brittle and dry with narrowing or splitting of the hair shaft. Iron replacement restored hair growth in those whose sole issue was iron deficiency. (22-23)
5. GI Evaluation-The 4 R’s Depleted stomach acid leads to impaired protein digestion and decreased nutrient absorption. Disturbed GI flora leads to inadequate nutrient utilization. Pancreatic enzyme deficiency leads to malabsorption of essential fatty acids and zinc.
The “4 R’s” include: (24)
“Remove” inflammatory foods such as gluten, dairy, corn, soy, eggs and sugar. Eliminate gastric irritants like alcohol, caffeine or drugs. Infections, even low grade infections need to be treated with herbs, antiparasitic and antifungal medication, anti-fungal supplements and antibiotics when appropriate.
“Replace” essential nutrients for proper utilization of foodstuffs. Digestive enzymes, hydrochloric acid and bile salts are needed for proper digestion. “Restore ” normal GI flora. Probiotics containing bifidobacteria and lactobacillus
dosed from 25 to 100 billion units a day along with prebiotics and fiber.
“Repair, ” L-glutamine along with zinc, omega 3 fish oil, vitamins A, C, E, slippery elm and aloe vera containing supplements rebuilds the damaged intestinal wall.
Addressing Stress & Adrenal Fatigue Diagnosis: The HPA AXIS Stress Index Panel . A four point saliva test performed in a single day. Normal are high upon awakening and then quickly fall and flatten out by noon.
Treatment begins with reducing stress (easier said than). Proper diet, yoga, Pilates, Qi Gong, meditation, massage and infra red sauna are a few techniques used to successfully control stress. For some a complete lifestyle change may be the only way to better health. Supplements that enhance the adrenal glands include the adaptogenic herbs Rhodiola, Ginseng, and cordyceps , Pregnenolone, DHEA (cortisol precursors), 5 HTP (for sleep, well-being and mood regulation), adrenal glandulars (to balance cortisol and replenish the catecholamines dopamine, norepinephrine, and epinephrine), and if still no relief Cortef (low dose cortisone). 6. Male Hormones and Hair Loss: Natural DHT Blockers Saw Palmetto- Inhibits 5-alpha-reductase. 240-260 mg @ bedtime minimum. (25) Progesterone- “anti-feminizing in men.” Prevents excess conversion of testosterone to estrogen in males by blocking type 2 5alpha reductase. Nettle Root- Can be used topically with Coconut or Olive Oil and Rosemary extract as a shampoo. Pygeum- Inhibits DHT. Commonly used in combination with Saw Palmetto Rosemary Oil- Inhibits DHT. Use as scalp massage Pumpkin Seed Oil- Inhibits DHT. Can mix with apple cider vinegar as salad dressing.
7. Female Hormones and Hair Loss Proper balancing of bioidentical, not synthetic, progesterone to estrogen, will in many cases resolve hair loss. Fix the cause. 8. Alkalinize the Body Maximal DHT conversion occurs when the pH of the body is between 5.0 and 5.5. This corresponds to what is achieved by following the Standard American Diet. (S.A.D.) Alkalinizing the body prevents DHT from binding to hair follicles enabling them to thrive. A liver Detox such as Dr. Clearfield’s Ultimate Paleocleanse will restore scalp pH to at least 7 in two weeks. If the alkaline environment is maintained, hair will regrow, stronger and thicker than before.. Below is a food chart comparing the relative acidity or alkalinity of different food groups to one another. It is evident that the “normal” American sets him or herself up for failure by consuming highly acidic foods.
9. Delayed Food Allergies Do’s: Bone Broth- Helps restore gut barrier (i.e. heals the “leaky gut”) Fermented Vegetables and Beverages (i.e. sauerkraut, kimchi, beet kvass, coconut water kefir, etc.). High in Probiotics Fish and Shellfish- High in omega-3 fats. Eat at least one pound of cold-water, fatty fish per week EPA and DHA needs. Organ Meats- Loaded micronutrients that promote healthy immune function. Micronutrients Vitamins A & D : Immune enhancement. Vitamin D supports proper T-regulatory cell function. Cod liver oil is the best source of A & D. Iodine & Selenium – Crucial for immune health and successful conversion of T4 to T3. Glutathione : Promotes healthy function of T regulatory cells Niacin (B3), Pyridoxine (B6), Vitamin C, Magnesium, Iron, Copper, Zinc, and Manganese . Eliminate Gluten Soy Dairy Eggs Corn Saturated and/or trans fats Processed foods Sugar Substitute For: Salt: Powdered garlic, powdered onion, lemon juice, lime juice, lemon crystals, turmeric, ground cloves, oregano, ground allspice, celery seeds, coriander seeds, ground cardamom seeds Butter/Fat: Olive oil, coconut oil, flaxseed oil, ghee Sugar: Obtain sugar primarily from fruits and vegetables, not concentrated sources. Fruit purees flavored with lemon juice and spices (cinnamon, nutmeg, mint leaves, ginger, vanilla), Stevia, Xylitol in limited quantities. Alcohol :Limited to an occasional glass of wine, beer or spirits. Red wine contains a number of health promoting phytochemicals and antioxidants. Cereals : Nut flours (almond, pecan, walnut, hazelnut, etc.) can be made in a food processor Cheese: Nut cheeses (cashew, dairy, soy free) Milk: Almond milk, coconut milk Protein: Ancient Nutrition Protein Bone Broth Goitrogens (27) In small amounts goitrogens increase the need for iodine. In large quantities they can damage the thyroid. Goitrogens should be limited to 3-6 servings per week. Steaming can reduce the danger by ⅓ and thoroughly cooking them and discarding the water in case of boiling decreases the harm by 90%.
Cruciferous Vegetables C Others Bok Choy Broccoli Brussel Sprouts Cabbage Canola Cauliflower Chinese Cabbage Collard Greens Horseradish Kale Kohlrabi Mustard Greens Radishes Rutabaga Turnips Soy Pine Nuts, Peanuts Millet Strawberries Pears, Peaches Bamboo Shoots Spinach Sweet Potatoes
10. Compounded Formulas
a. Compounded Caffeine Formula (28) i. Caffeine 0.001% to 0.005% in VersaBase shampoo #4 oz (120cc) ii. Shampoo scalp. Leave on 15 minutes and wash off. Repeat daily. b. Zinc pyrithione 1% in topical solution with or without minoxidil 10%. 4oz (29) i. Sig: apply to hair follicles qhs. Cover with shower cap and leave on all night. Wash out in the am. c. Melatonin 1m/mL in VersaBase Shampoo #4őz. (120cc) (30) i. Sig: shampoo daily. Leave on for 10 minutes and then wash off. d. Minoxidil 8.5%/Finasteride 0.1% scalp solution #2 oz. (31) i. Sig: apply to hair follicles qhs. Cover with shower cap and leave on all night. Wash out in the am. 11. New Trends Platelet Rich Plasma Platelet-rich plasma (PRP) is created by collecting blood from the patient and spinning it in a centrifuge to separate the platelets from the blood. After applying local anesthetics to the scalp, PRP is combined with an FDA approved biomatrix (Acell) and nutrients, then either injected or via a micro-needling device, or applied to localized areas such as the eyebrows or beard, or the full scalp. PRP contains many growth factors to stimulate the hair follicle restoration. It stimulates inactive or newly implanted hair follicles into an active growth phase. Following up with progesterone or a melatonin based scalp treatment enhances the process. New hair sprouts as early as 2 months. 4-8 months is the typical time frame for hair to thicken and become noticeable. Additional injections may be necessary every 2 years. Recovery time is minimal and pain is usually managed with over the counter ibuprofen or homeopathic remedies such as Arnica Montana and/or Boswellia. “Hair loss reduced and at 3 months it reached normal levels. Hair density reached a peak at 3 months. At 6 months and at 1 year, it was significantly increased, 156.25 ± 37.75 (P < 0.001) and 153.70 ± 39.92 (P < 0.001) respectively, comparing to baseline. Patients
were satisfied with a mean result rating of 7.1 on a scale of 1-10. No remarkable adverse effects were noted.” (32) “A mean increase of 33.6 hairs in the target area and a mean increase in total hair density of 45.9 hairs per cm² compared with baseline values. No side effects were noted during treatment. The data clearly highlight the positive effects of PRP injections on male pattern hair loss and absence of major side effects.” (33) “PRP was found to increase hair regrowth significantly and to decrease hair dystrophy and burning or itching sensation compared with TrA or placebo. Ki-67 levels, which served as markers for cell proliferation, were significantly higher with PRP. No side-effects were noted during treatment.” (34) No Stitch Transplant As advertised, no stitches and no staples. There is little-to-no discomfort (no scalpel involved). Patients resume normal activity after only a few days. The hair line is natural looking with no linear scar. Low Level Laser Therapy Laser light, specifically the red visible wavelengths target tissue molecules. The energy level of the molecules increases and the molecules respond by “working off” the excess energy with adaptive changes. In the case of hair follicles this adaptive change is the stimulation of new, thicker follicular growth. Conclusion Hair loss is as simple as hereditary or an early warning sign of a serious health condition. While, at present, surgical transplant is the only way to overcome Dad’s chrome dome, infections, autoimmune issues, scarring, inadequate protein and essential vitamin deficiencies, medications and stress also plays a role. Proper treatment demands we search for the underlying cause. Call us at 775-359-1222 or email [email protected] to find your answers.
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Dr. William Clearfield
Address : 9550 S McCarran Blvd b, Reno, NV 89523 Phone : 775-359-1222 Fax : 888-977-3503 Email : [email protected] Website : drclearfield.net
References 1. http://ift.tt/2xqUcsS 2. Rogers, N., et al., “Medical treatments for male and female pattern hair loss,” Jour Amer Acad Derm 2008; 59(4):547-66. 3. http://ift.tt/2xYvhZ4 wth-cycle.jpg&imgrefurl=http%3A%2F%2Fwww.oblique.co.nz%2Fhair_health%2Fhairstructure.html&docid=Qa VBvcatbRCqpM&tbnid=4BJnp5uQ83LuVM%3A&vet=10ahUKEwiqvsWW_6DVAhWm7oMKHXpgAgYQMwgqK AMwAw..i&w=400&h=178&bih=635&biw=1351&q=life%20cycle%20of%20a%20hair%20follicle&ved=0ahUKEwi qvsWW_6DVAhWm7oMKHXpgAgYQMwgqKAMwAw&iact=mrc&uact=8 4. K. S. Stenn & R. Paus (1 January 2001). “Controls of Hair Follicle Cycling”. Physiological Reviews. 81 (1): 449–494. PMID 11152763. 5. http://ift.tt/2z75wru 6. http://ift.tt/1H7sk92 7. The Birth of Modern Culture, Digital History, http://ift.tt/2z7ED6S, accessed September 7, 2015. 8. http://ift.tt/2xqUdwW 9. Murray, M., et al., Hair Loss in Women. In Pizzorno, J., and Murray, M., Textbook of Natural Medicine St. Louis: Elsevier/Churchill Livingstone, 2013, p. 1406-08 10. Mounsey., A., et al., “Diagnosing and treating hair loss,” Amer Fam Physician 2009; 80(4):356-62. 11. Kalz, F., “Cicatricial alopecia and vitamin A,” Arch Dermatol 1958; 78:740-43. 12. Mesinkovska, N., et al., “Hair: what is new in diagnosis and management? Female pattern hair loss update,” Dermatol Clin 2013; 31(1):119-27. 13. Rothenberg, Ron, Thyroid Optimization, BHRT Syllabus, A4M Lecture Series, Los Angeles, CA, February 26, 2015, p. 62. 14. Clearfield, W., Patient Mysteries; Are You Thyroid Deficient, Healthy Beginning Magazine, August 31, 2015,
Patient Mysteries: Are you thyroid deficient?
15. http://ift.tt/2yBWiWA or-healthy-hair-skin-and-nails#d89PpsjmUPybGAjQ.97 16. Krause, K., et al., “Vitamin status in patients on chronic anticonvulsant therapy,” Int Jour Vitamin Nutri Res 1982; 5294):375-85. 17. Mock, D., et al., “Biotin catabolism is accelerated in adults receiving long-term therapy with anticonvulsants,” Neurology 1997; 49:1444-47. 18. Wolowa, F., et al., “Zinc sulfate in the treatment of alopecia areata,” (Article in Polish) Przeg Derm 1978; 65:687-96. 19. Murray, M., et al., Hair Loss in Women. In Pizzorno, J., and Murray, M., Textbook of Natural Medicine. St. Louis: Elsevier/Churchill Livingstone, 2013, p. 1406-08. 20. Shmunes, E., “Hypervitaminosis A in a patient with alopecia receiving renal dialysis,” Arch Dermatol 1979; 115:882-83. 21. McKenzie, D, How Much Protein to Prevent Hair Loss, http://ift.tt/2z75y2A November 18, 2015. 22. Moeinvaziri, M., et al., “Iron status in diffuse telogen hair loss among women,” Acta Dermatovenerol Croat 2009; 17(4):279-84. 23. Hard, G., “Non-anemic iron deficiency as an etiologic factor in diffuse loss of hair of the scalp in women,” Acta Derm Venereol 1963; 43:562-69. 24. Reasoner, J., LeakyGut Syndrome in Plain English – and How to Fix It, http://ift.tt/1LYkCkQ, Accessed September 6, 2015 25. Prager, N., et al., “A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5- alpha-reductase in the treatment of androgenic alopecia,” Jour Altern Complement Med 2002;8:143-52. 26. http://ift.tt/2yHL5mT mtDWQAKVYoAl-ZwxINw 27. Kresser, C. Clinician’s Guide to Thyroid Disease, Kresser Institute;2016:5-6 28. Bussoletti, C., et al., “Use of a cosmetic caffeine lotion in the treatment of male androgenetic alopecia,” Jour of Applied Cosmetology 2011; 29(4):167-79. 29. Berger, R., et al., “The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial,” Brit Jour Dermatol 2003; 149(2):354-62. 30. Fischer, T., et al., “Melatonin increases antagen hair rate in women with androgenetic alopecia or diffuse alopecia: results of a pilot randomized controlled trial,” Brit Jour Dermatol 2004; 150:341-45. 31. A4M Module XIV; Module XXIV: The Nuts and Bolts of Writing Prescriptions for Compounded Medications:The Ultimate in Personalized Medicine: Del Ray Beach, Florida, June 24-26, 2014 32. Maria-Angeliki Gkini, Alexandros-Efstratios Kouskoukis, Gregory Tripsianis,1 Dimitris Rigopoulos,2 and Konstantinos Kouskoukis, Study of Platelet-Rich Plasma Injections in the Treatment of Androgenetic Alopecia Through an One-Year Period, J Cutan Aesthet Surg. 2014 Oct-Dec; 7(4): 213–219. doi: 10.4103/0974-2077.150743 33. Gentile P1, Garcovich S2, Bielli A3, Scioli MG3, Orlandi A3, Cervelli V4., The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial. Stem Cells Transl Med. 2015 Nov;4(11):1317-23. doi: 10.5966/sctm.2015-0107. Epub 2015 Sep 23. 34. Trink A1, Sorbellini E, Bezzola P, Rodella L, Rezzani R, Ramot Y, Rinaldi F., A randomized, double-blind, placebo- and active-controlled, half-head study to evaluate the effects of platelet-rich plasma on alopecia areata. Br J Dermatol. 2013 Sep;169(3):690-4. doi: 10.1111/bjd.12397.
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Hair Restoration Project | Dr William Clearfield Reno
Hair Restoration Project | Dr William Clearfield Reno
The Hair Restoration Project PRP technique can treat male and female pattern hair loss, alopecia areata, and eyebrow hypotrichosis
Below there is a lot about thinning hair in Reno…I mean a lot of information. More than you need but it is important that you have the option of knowing everything there is to know about male and female pattern baldness and hair loss treatments in Reno NV. This article is about understanding hair loss and how and why your thinning hair and baldness pattern can be replaced without surgery.
Contact Dr. William Clearfield at the Clearfield Medical Group to schedule your consultation to see if the Hair Restoration Project is right for your male or female pattern baldness. 1-775-359-1222 and go to your website www.drclearfield.net
More information on the “Hair Restoration Project” go to http://ift.tt/2yHJH3y
Who doesn’t admire a fine head of hair? We covet, envy, and even worship a great head of hair..My late great mother, (lung cancer, not from cigarettes, bad but too much casino air, Atlantic CIty, New Jersey) in hospice, on the day before she passed, woke from her morphine induced “sleep”, looked around at us sitting by her bedside, and asked, “How’s my hair?” Her final words. (True, story. To be fair, Mom was always a Jackie Kennedy, never Onassis, wannabe.) Millions aren’t so lucky. In the United States, by age 60, 65% of men, and 80% of women have noticeable hair loss. In total 56 million men and women experience hair loss.(2)
To understand hair loss and what can be done to correct it, we must understand the natural growth, and demise, of a single hair follicle. Hair growth takes place in four phases:(4)
1. ACTIVE GROWTH (ANAGEN) PHASE The active growth phase lasting two to six years. Hair grows 18 to 24 inches before entering into the transitional phase. 80-90% of all hair follicles are in this growth phase on a healthy head. 2. TRANSITIONAL (CATAGEN) PHASE The shortest of the hair cycles lasting one to two weeks occurs when the lower third of the hair follicle is cut off from its blood supply. The hair itself shrinks to 1/6 its expected length. Catagen hair accounts for 2-3% of all follicles at any one time. 3. RESTING PHASE (TELOGEN) PHASE The dormant stage lasting one to four months. 10-15% of all hairs are in the Telogen phase. Telogen hair sheds or is pushed out by new hair follicles as the cycle renews. Ideally only 10-15% of hairs are telogenic. When more than 20% of hair are in this “resting” phase, noticeable thinning occurs. 4. SHEDDING PHASE (EXOGEN) PHASE Hairs in this phase shed easily as the follicles are preparing to return to the Anagen phase.
Types of Hair Loss (5) 1. TELOGEN EFFLUVIUM An abnormally high percentage of hair in the Telogen phase results in an overall thinning of hair. Common causes of this type of hair loss include chronic stress, toxins, fungal infections, nutritional deficiencies, and hormonal imbalances. 2. ANDROGENETIC ALOPECIA “Male-pattern” baldness is not limited to men. In women, the hair thins at the crown or widens in the part. The hair thins revealing a bare scalp. 3. ALOPECIA AREATA Presents as patches of lost hair. Alopecia Areata is usually an autoimmun condition with an association of nail issues also. 4. MISCELLANEOUS TYPES a. Traction from braids, weaves or wigs b. Chemotherapy-Related Hair Loss c. Frontal Fibrosing Alopecia (FFA) d. Lichen Planopilaris (LPP) Etiology of Hair Loss (6) 1. Sub-Optimal Thyroid Function The thyroid is the body’s “gas pedal,” determining how fast, or slow all bodily functions operate. When slowed due to inadequate “fuel,” namely usable thyroid substrate, the oils, fluids and tissues, especially the hair follicles function inadequately. The hair follicles spend an abnormal amount of time, and hence an abnormal number of hair follicles are in the Telogen or resting phase, resulting in a form of Telogen Effluvium. 2. Nutritional Deficiencies Nutritional deficiencies, specifically silica and zinc leads to hair loss. Micronutrient testing is indicated when this is suspected. 3. Stress In 1881, George Miller Beard, M.D., a neurologist and graduate from the New York College of Physicians and Surgeons, described a condition based on excess “nervous energy.” Constant over stimulation of the nervous system from the fast paced American lifestyle resulted in “neurasthenia,” burnout, or nervous exhaustion.
Symptoms of neurasthenia included nervous dyspepsia, insomnia, hysteria, hypochondria, asthma, sick-headache, skin rashes, hay fever, premature baldness, inebriety, hot and cold flashes, nervous exhaustion, brain-collapse, and forms of ‘elementary insanity. The best educated and most sophisticated Americans were the most afflicted. Theodore Roosevelt and Frederic Remington were two prominent figures of their day suffering from “neurasthenia.”
The “cure” was a withdrawal from the modern life, rest and a less hectic lifestyle. Critics countered that urban life in the late nineteenth century had produced a “pathetic, pampered, physically and morally enfeebled 97 pound weaklings, unworthy successors to the stalwart Americans who had fought the Civil War and tamed a continent.”.(7)
Physicians pigeonholed patients into this “nervous energy” category, relieving themselves of more vigilant diagnosis. Early signs of tuberculosis, heart failure and epilepsy were chalked up to neurasthenia and when later discovered to be in error, gave fuel to those who saw this “malady,” as a sham. The term neurasthenia is no longer used to describe any medical condition, but the conditions that lead to its “discovery,” diagnosis and its’ symptoms are remarkably similar to a hormonal condition with distinct diagnostic criteria known as “Adrenal Fatigue.”
The adrenal glands, pea sized organs, sit on top of the kidneys. They produce hormones that regulate blood pressure, electrolytes balance, blood sugar, immune responses, digestion, and stress responses. In regards to the latter, constant unremitting stress, as experienced by nearly everyone in today’s society, hijacks normal hormonal responses, redeploying the adrenals’ resources, in the form of the hormone cortisol, to combat the “evil” of the moment. The other adrenal functions, digestion, immune response, and thyroid hormone production, are temporarily put on hold or slowed until the stress has passed.
Cortisol is our protector. It lies in wait, like the lineup of computer programs opened at startup and running in the background, ready at an instant, when needed, to spring into action. In an ideal world, the stressor passes quickly and the adrenals resume lurking behind the scene awaiting the next crisis. In our non-ideal world, one stress begets a second stress, which begets a third stress, ad infinitum, putting the adrenal gland into permanent overdrive. The body is flooded with cortisol driving the adrenals to handle the stress but eventually it cannot keep up. The result is adrenal “burnout” or fatigue.
The thyroid is exquisitely impacted by the constant flooding and eventual depletion of cortisol. High levels signal the brain to lower the production of stressor hormones. Unfortunately, thyroid hormone is produced in the same pathway and is unwittingly lowered. Recall the critical step of converting T4 to the usable thyroid hormone free T3. Stress hormones affect the enzymes that convert T4 to T3 converting T4 into an inert unusable reverse T3.
Chronically elevated cortisol levels release inflammatory cells which desensitizes thyroid receptors to thyroid hormone. Like diabetics who don’t respond to insulin, adequate thyroid hormone may exist, but the result is inadequate thyroid utilization.
Increased circulatory cortisol increases estrogen in the blood stream. Estrogen increases thyroid binding globulin, tying up T3 and T4, reducing hormone levels to achieve the conversion to free T3. Elevated cortisol levels with its’ inherent state of chronic inflammation can trigger “leaky gut syndrome,” latent infections leading and autoimmune diseases.
Hair follicles accumulate in the resting (Telogen) phase.
4. Sex Hormone Imbalances Male: Excess testosterone metabolizes into dihydrotestosterone (DHT) and estradiol. DHT attaches to hair follicles, effectively strangling them causing “organ” death. The key to preventing, slowing, or possibly reversing the effects of DHT is by inhibiting this conversion of Testosterone into DHT. (Essentially the mechanism of action of hair loss products such as Rogaine.)
Type 2 5alpha reductase is the enzyme that that converts testosterone into DHT. Type 2 5alpha reductase is primarily found in the hair follicles and the prostate gland.
The conversion of too much testosterone to DHT results in androgenetic alopecia. As a man ages he retains estrogen and converts testosterone into estrogen at a higher rate. The result is 1+1=4, the 4 being excess DHT as a result of excess estrogen.
Women: Estrogen dominance is the culprit in women. Child birth, birth control medications, stress, toxins, along with entrance into the perimenopausal arena, creates an estrogen dominant pattern. Estrogen signals the liver to produce inordinate amounts of Thyroid Binding Globulin (TBG). T4, the “storage unit” of the thyroid must convert to T3, the hormone that the “work.” Excess TBG leads to an inability to convert T4 to T3, resulting in a relative hypothyroidism and Telogen Effluvium. Estrogen dominance results in excess DHT, leading to a female version of “male pattern” baldness. (8) Miscellaneous areas to explore if estrogen dominance is ruled out: Heredity, insulin resistance, polycystic ovarian syndrome and a low antioxidant state. (9)
5. Medications Causing Hair Loss (10) Antibiotics: gentamicin, chloramphenicol Anticoagulants: warfarin, heparin Antidepressants: fluoxetine, desipramine, lithium Anticonvulsants: valproic acid, phenytoin, carbamazepine Cardiovascular meds: ACE inhibitors, beta blockers Chemotherapy drugs: doxorubicin, vincristine, etoposide Endocrine drugs: bromocriptine, clomiphene, danazol Gout medications: colchicine, allopurinol Lipid lowering drugs: gemfibrozil, fenofibrate, cholestyramine, clofibrate NSAIDS: ibuprofen, indomethacin, naproxen Reflux/ulcer medications: cimetidine, ranitidine, famotidine Antithyroid drugs: iodine, PTU Retinoids: vitamin A overdose, isotretinoin 6. Trichotillomania- Repetitive hair pulling resulting in hair loss. Considered an OCD variant. Treatment usually includes behavioral therapies, SSRI’s or other drugs to treat OCD. Metabolic therapies include NAC, inositol, L-tryptophan, niacin and vitamin B6.
7. Scarring Alopecia- Resulting from burns, radiation, or other injuries or diseases. Destroys the dermis with permanent hair loss. Rx: Vitamin A 150,000 IU qd for 6 weeks stopped disease progression. Maintenance Rx: 150,000 IU qd for three 6 week periods every year. (11)
Conventional Therapies for Hair Loss (12)
Cyproterone acetate Minoxidil Flutamide Ketoconazole Finasteride Hair Transplantation Dutasteride Light Therapy, Botulinum Toxins Holistic Resolutions to Hair Loss
1. Proper Hypothyroidism Diagnosis & Treatment (13-14)
The thyroid functions as the body’s “gas pedal.” Like Goldilocks, we need it to be just right, not too little, not too much. The gland produces two major hormones, triiodothyronine (T3), the active hormone, and thyroxine (T4), the storage hormone. The thyroid also produces calcitonin, a hormone responsible for calcium balance and bone density and magnesium.
98% of all thyroid disorders results in hypothyroidism. Common symptoms include cold intolerance, unexplained weight gain, fatigue, thinning of the hair, the outer third of the eyebrow, the skin and the nails, increased body fat, energy loss, cognitive loss, memory loss, mood disorders, lowered body temperature (never greater than 97.6 F), fluid retention, and a poor sense of well-being.
When the underlying cause of hypothyroidism is the immune system, not the thyroid per se., and it is not addressed, the treatment will not be effective. 25 percent of patients with autoimmune, Hashimoto’s thyroiditis develop polyglandular syndromes (such as pernicious anemia, diabetes, or adrenal insufficiency) or other autoimmune diseases (such as Sjogren’s syndrome).
2. Key Supplements for Healthy Hair (15)
Biotin- Water-soluble B-vitamin found in green leafy vegetables. Regulates mitochondrial enzymes in hair follicles. Depleted by cigarette smoking, aging, excess alcohol, strenuous exercise, burn victims, shortened gut syndrome (GI resections), achlorhydria, and raw egg consumption. (16-17) Use orally or in essential oil mixture. Dose is 30-100 mcg/day.
Zinc -Promotes cell reproduction, tissue growth and repair of broken tissues. Maintains the oil-secreting glands attached to hair follicles. Study showed that 15 patients with alopecia areata received 45 mg of zinc TID. All had complete return of hair growth within 6 months. (18) Maintenance dose is 15 mg per day along with 1 mg copper as a balance.
N-Acetyl-Cysteine- Precursor to glutathione the most powerful antioxidant in the body. Protects DNA from chemical damage, detoxifies heavy metals, and it keeps arteries and airways open. It activates important functions of the immune system.
B Vitamins (B6, B12)- In the form of Pyridoxal 5-Phosphate (PLP), the B Vitamins act as catalysts to activate the enzymes and chemical reactions to commence the metabolism of keratin and melanin in the hair follicles. B vitamins control hormone release., regulating androgen interaction with hair metabolism. Testosterone breaks down into dihydrotestosterone (DHT). Elevated DHT levels diminishes hair growth by decreasing the length of the anagen, hair growth phase, and the follicle size. Vitamin B6 binds to the testosterone receptors, stopping DHT formation.
Niacin- Vitamin B3 converts carbohydrates into energy, delivers the energy to cells where needed and maintains cell integrity. Niacin is a vasodilator, hence the niacin “flush” so common when taken, “washes” carbohydrates through the body, reducing visceral fat and serum cholesterol. The flush can be minimized by taking niacin with a meal or starting (with a) low dose and gradually increasing its potency. The vasodilator effect of niacin delivers increased oxygen and nutrients to the hair follicle resulting in thicker hair.
Arginine- L-arginine, a precursor to nitrogen oxide, opens the potassium channels of the cell, improving blood supply to the hair root.
Lysine- An essential amino acid, lysine stimulates collagen and is necessary for restoring damaged hair. Food sources for lysine include fish (especially salmon, sardines and cod), dairy, poultry, red meat, pork, legumes, nuts, spirulina and pulses.
Saw Palmetto (for Men)- Prevents conversion of testosterone to DHT
Acetyl-L-Carnitine- Up regulates proliferation and down regulates apoptosis in hair follicle keratinocytes. Turns fat into energy. Acetyl-L Carnitine improves the membrane potential of the hair follicle which is significantly diminished along with potassium channel function within withering hair follicles.
Iron- A lack of iron results in a decrease in hemoglobin, the ingredient that carries oxygen for growth and repair of all cells including hair follicles. Iron deficiency states move hair follicles into a premature and prolonged telogen (resting) phase. Hair growth is a “non-essential” bodily function. It is one of the first systems to shut down in a state of iron deficiency. Hence, hair loss is an early warning sign of iron deficiency anemia.
Vitamin D- Essential for calcium homeostasis, immune regulation and cell growth. A host of autoimmune diseases, including alopecia areata, exhibit low levels of Vitamin D. The severity of serum 25(OH)D deficiency is inversely related to the severity of hair loss.
Gluten- Hair loss is an early sign of gluten intolerance. In all cases of alopecia or extensive hair loss, we recommend a strict gluten free diet for 4 weeks as a trial. (19)
Vitamin A- Hair loss is a symptom of Vitamin A toxicity especially in renal failure. Usually resolves when toxicity is addressed. (20)
Emu Oil- Contains linolenic acid a potent 5-alpha reductase inhibitor. Compound with virgin coconut oil to create an antibacterial, anti-inflammatory scalp treatment to DHT.
3. Adequate Protein Insufficient protein effects on your hair growth. The CDC recommends 46 to 56 grams of protein per tain to maintain hair growth. (21) Inadequate protein results in protein rationing by shutting down less important functions.
4. Iron When iron levels fall below 30 mg/L hair growth and regeneration are decreased. Iron deficiency commonly causes hair to be brittle and dry with narrowing or splitting of the hair shaft. Iron replacement restored hair growth in those whose sole issue was iron deficiency. (22-23)
5. GI Evaluation-The 4 R’s Depleted stomach acid leads to impaired protein digestion and decreased nutrient absorption. Disturbed GI flora leads to inadequate nutrient utilization. Pancreatic enzyme deficiency leads to malabsorption of essential fatty acids and zinc.
The “4 R’s” include: (24)
“Remove” inflammatory foods such as gluten, dairy, corn, soy, eggs and sugar. Eliminate gastric irritants like alcohol, caffeine or drugs. Infections, even low grade infections need to be treated with herbs, antiparasitic and antifungal medication, anti-fungal supplements and antibiotics when appropriate.
“Replace” essential nutrients for proper utilization of foodstuffs. Digestive enzymes, hydrochloric acid and bile salts are needed for proper digestion. “Restore ” normal GI flora. Probiotics containing bifidobacteria and lactobacillus
dosed from 25 to 100 billion units a day along with prebiotics and fiber.
“Repair, ” L-glutamine along with zinc, omega 3 fish oil, vitamins A, C, E, slippery elm and aloe vera containing supplements rebuilds the damaged intestinal wall.
Addressing Stress & Adrenal Fatigue Diagnosis: The HPA AXIS Stress Index Panel . A four point saliva test performed in a single day. Normal are high upon awakening and then quickly fall and flatten out by noon.
Treatment begins with reducing stress (easier said than). Proper diet, yoga, Pilates, Qi Gong, meditation, massage and infra red sauna are a few techniques used to successfully control stress. For some a complete lifestyle change may be the only way to better health. Supplements that enhance the adrenal glands include the adaptogenic herbs Rhodiola, Ginseng, and cordyceps , Pregnenolone, DHEA (cortisol precursors), 5 HTP (for sleep, well-being and mood regulation), adrenal glandulars (to balance cortisol and replenish the catecholamines dopamine, norepinephrine, and epinephrine), and if still no relief Cortef (low dose cortisone). 6. Male Hormones and Hair Loss: Natural DHT Blockers Saw Palmetto- Inhibits 5-alpha-reductase. 240-260 mg @ bedtime minimum. (25) Progesterone- “anti-feminizing in men.” Prevents excess conversion of testosterone to estrogen in males by blocking type 2 5alpha reductase. Nettle Root- Can be used topically with Coconut or Olive Oil and Rosemary extract as a shampoo. Pygeum- Inhibits DHT. Commonly used in combination with Saw Palmetto Rosemary Oil- Inhibits DHT. Use as scalp massage Pumpkin Seed Oil- Inhibits DHT. Can mix with apple cider vinegar as salad dressing.
7. Female Hormones and Hair Loss Proper balancing of bioidentical, not synthetic, progesterone to estrogen, will in many cases resolve hair loss. Fix the cause. 8. Alkalinize the Body Maximal DHT conversion occurs when the pH of the body is between 5.0 and 5.5. This corresponds to what is achieved by following the Standard American Diet. (S.A.D.) Alkalinizing the body prevents DHT from binding to hair follicles enabling them to thrive. A liver Detox such as Dr. Clearfield’s Ultimate Paleocleanse will restore scalp pH to at least 7 in two weeks. If the alkaline environment is maintained, hair will regrow, stronger and thicker than before.. Below is a food chart comparing the relative acidity or alkalinity of different food groups to one another. It is evident that the “normal” American sets him or herself up for failure by consuming highly acidic foods.
9. Delayed Food Allergies Do’s: Bone Broth- Helps restore gut barrier (i.e. heals the “leaky gut”) Fermented Vegetables and Beverages (i.e. sauerkraut, kimchi, beet kvass, coconut water kefir, etc.). High in Probiotics Fish and Shellfish- High in omega-3 fats. Eat at least one pound of cold-water, fatty fish per week EPA and DHA needs. Organ Meats- Loaded micronutrients that promote healthy immune function. Micronutrients Vitamins A & D : Immune enhancement. Vitamin D supports proper T-regulatory cell function. Cod liver oil is the best source of A & D. Iodine & Selenium – Crucial for immune health and successful conversion of T4 to T3. Glutathione : Promotes healthy function of T regulatory cells Niacin (B3), Pyridoxine (B6), Vitamin C, Magnesium, Iron, Copper, Zinc, and Manganese . Eliminate Gluten Soy Dairy Eggs Corn Saturated and/or trans fats Processed foods Sugar Substitute For: Salt: Powdered garlic, powdered onion, lemon juice, lime juice, lemon crystals, turmeric, ground cloves, oregano, ground allspice, celery seeds, coriander seeds, ground cardamom seeds Butter/Fat: Olive oil, coconut oil, flaxseed oil, ghee Sugar: Obtain sugar primarily from fruits and vegetables, not concentrated sources. Fruit purees flavored with lemon juice and spices (cinnamon, nutmeg, mint leaves, ginger, vanilla), Stevia, Xylitol in limited quantities. Alcohol :Limited to an occasional glass of wine, beer or spirits. Red wine contains a number of health promoting phytochemicals and antioxidants. Cereals : Nut flours (almond, pecan, walnut, hazelnut, etc.) can be made in a food processor Cheese: Nut cheeses (cashew, dairy, soy free) Milk: Almond milk, coconut milk Protein: Ancient Nutrition Protein Bone Broth Goitrogens (27) In small amounts goitrogens increase the need for iodine. In large quantities they can damage the thyroid. Goitrogens should be limited to 3-6 servings per week. Steaming can reduce the danger by ⅓ and thoroughly cooking them and discarding the water in case of boiling decreases the harm by 90%.
Cruciferous Vegetables C Others Bok Choy Broccoli Brussel Sprouts Cabbage Canola Cauliflower Chinese Cabbage Collard Greens Horseradish Kale Kohlrabi Mustard Greens Radishes Rutabaga Turnips Soy Pine Nuts, Peanuts Millet Strawberries Pears, Peaches Bamboo Shoots Spinach Sweet Potatoes
10. Compounded Formulas
a. Compounded Caffeine Formula (28) i. Caffeine 0.001% to 0.005% in VersaBase shampoo #4 oz (120cc) ii. Shampoo scalp. Leave on 15 minutes and wash off. Repeat daily. b. Zinc pyrithione 1% in topical solution with or without minoxidil 10%. 4oz (29) i. Sig: apply to hair follicles qhs. Cover with shower cap and leave on all night. Wash out in the am. c. Melatonin 1m/mL in VersaBase Shampoo #4őz. (120cc) (30) i. Sig: shampoo daily. Leave on for 10 minutes and then wash off. d. Minoxidil 8.5%/Finasteride 0.1% scalp solution #2 oz. (31) i. Sig: apply to hair follicles qhs. Cover with shower cap and leave on all night. Wash out in the am. 11. New Trends Platelet Rich Plasma Platelet-rich plasma (PRP) is created by collecting blood from the patient and spinning it in a centrifuge to separate the platelets from the blood. After applying local anesthetics to the scalp, PRP is combined with an FDA approved biomatrix (Acell) and nutrients, then either injected or via a micro-needling device, or applied to localized areas such as the eyebrows or beard, or the full scalp. PRP contains many growth factors to stimulate the hair follicle restoration. It stimulates inactive or newly implanted hair follicles into an active growth phase. Following up with progesterone or a melatonin based scalp treatment enhances the process. New hair sprouts as early as 2 months. 4-8 months is the typical time frame for hair to thicken and become noticeable. Additional injections may be necessary every 2 years. Recovery time is minimal and pain is usually managed with over the counter ibuprofen or homeopathic remedies such as Arnica Montana and/or Boswellia. “Hair loss reduced and at 3 months it reached normal levels. Hair density reached a peak at 3 months. At 6 months and at 1 year, it was significantly increased, 156.25 ± 37.75 (P < 0.001) and 153.70 ± 39.92 (P < 0.001) respectively, comparing to baseline. Patients
were satisfied with a mean result rating of 7.1 on a scale of 1-10. No remarkable adverse effects were noted.” (32) “A mean increase of 33.6 hairs in the target area and a mean increase in total hair density of 45.9 hairs per cm² compared with baseline values. No side effects were noted during treatment. The data clearly highlight the positive effects of PRP injections on male pattern hair loss and absence of major side effects.” (33) “PRP was found to increase hair regrowth significantly and to decrease hair dystrophy and burning or itching sensation compared with TrA or placebo. Ki-67 levels, which served as markers for cell proliferation, were significantly higher with PRP. No side-effects were noted during treatment.” (34) No Stitch Transplant As advertised, no stitches and no staples. There is little-to-no discomfort (no scalpel involved). Patients resume normal activity after only a few days. The hair line is natural looking with no linear scar. Low Level Laser Therapy Laser light, specifically the red visible wavelengths target tissue molecules. The energy level of the molecules increases and the molecules respond by “working off” the excess energy with adaptive changes. In the case of hair follicles this adaptive change is the stimulation of new, thicker follicular growth. Conclusion Hair loss is as simple as hereditary or an early warning sign of a serious health condition. While, at present, surgical transplant is the only way to overcome Dad’s chrome dome, infections, autoimmune issues, scarring, inadequate protein and essential vitamin deficiencies, medications and stress also plays a role. Proper treatment demands we search for the underlying cause. Call us at 775-359-1222 or email [email protected] to find your answers.
I hope you liked the article on Male and female pattern hair loss, alopecia areata, and eyebrow hypotrichosis in Reno.
Call Dr. William Clearfield for a consultation appointment and be sure to watch our weekly Reno acupuncture tips at https://goo.gl/HcK7Gt
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Dr. William Clearfield
Address : 9550 S McCarran Blvd b, Reno, NV 89523 Phone : 775-359-1222 Fax : 888-977-3503 Email : [email protected] Website : drclearfield.net
References 1. http://ift.tt/2xqUcsS 2. Rogers, N., et al., “Medical treatments for male and female pattern hair loss,” Jour Amer Acad Derm 2008; 59(4):547-66. 3. http://ift.tt/2xYvhZ4 wth-cycle.jpg&imgrefurl=http%3A%2F%2Fwww.oblique.co.nz%2Fhair_health%2Fhairstructure.html&docid=Qa VBvcatbRCqpM&tbnid=4BJnp5uQ83LuVM%3A&vet=10ahUKEwiqvsWW_6DVAhWm7oMKHXpgAgYQMwgqK AMwAw..i&w=400&h=178&bih=635&biw=1351&q=life%20cycle%20of%20a%20hair%20follicle&ved=0ahUKEwi qvsWW_6DVAhWm7oMKHXpgAgYQMwgqKAMwAw&iact=mrc&uact=8 4. K. S. Stenn & R. Paus (1 January 2001). “Controls of Hair Follicle Cycling”. Physiological Reviews. 81 (1): 449–494. PMID 11152763. 5. http://ift.tt/2z75wru 6. http://ift.tt/1H7sk92 7. The Birth of Modern Culture, Digital History, http://ift.tt/2z7ED6S, accessed September 7, 2015. 8. http://ift.tt/2xqUdwW 9. Murray, M., et al., Hair Loss in Women. In Pizzorno, J., and Murray, M., Textbook of Natural Medicine St. Louis: Elsevier/Churchill Livingstone, 2013, p. 1406-08 10. Mounsey., A., et al., “Diagnosing and treating hair loss,” Amer Fam Physician 2009; 80(4):356-62. 11. Kalz, F., “Cicatricial alopecia and vitamin A,” Arch Dermatol 1958; 78:740-43. 12. Mesinkovska, N., et al., “Hair: what is new in diagnosis and management? Female pattern hair loss update,” Dermatol Clin 2013; 31(1):119-27. 13. Rothenberg, Ron, Thyroid Optimization, BHRT Syllabus, A4M Lecture Series, Los Angeles, CA, February 26, 2015, p. 62. 14. Clearfield, W., Patient Mysteries; Are You Thyroid Deficient, Healthy Beginning Magazine, August 31, 2015,
Patient Mysteries: Are you thyroid deficient?
15. http://ift.tt/2yBWiWA or-healthy-hair-skin-and-nails#d89PpsjmUPybGAjQ.97 16. Krause, K., et al., “Vitamin status in patients on chronic anticonvulsant therapy,” Int Jour Vitamin Nutri Res 1982; 5294):375-85. 17. Mock, D., et al., “Biotin catabolism is accelerated in adults receiving long-term therapy with anticonvulsants,” Neurology 1997; 49:1444-47. 18. Wolowa, F., et al., “Zinc sulfate in the treatment of alopecia areata,” (Article in Polish) Przeg Derm 1978; 65:687-96. 19. Murray, M., et al., Hair Loss in Women. In Pizzorno, J., and Murray, M., Textbook of Natural Medicine. St. Louis: Elsevier/Churchill Livingstone, 2013, p. 1406-08. 20. Shmunes, E., “Hypervitaminosis A in a patient with alopecia receiving renal dialysis,” Arch Dermatol 1979; 115:882-83. 21. McKenzie, D, How Much Protein to Prevent Hair Loss, http://ift.tt/2z75y2A November 18, 2015. 22. Moeinvaziri, M., et al., “Iron status in diffuse telogen hair loss among women,” Acta Dermatovenerol Croat 2009; 17(4):279-84. 23. Hard, G., “Non-anemic iron deficiency as an etiologic factor in diffuse loss of hair of the scalp in women,” Acta Derm Venereol 1963; 43:562-69. 24. Reasoner, J., LeakyGut Syndrome in Plain English – and How to Fix It, http://ift.tt/1LYkCkQ, Accessed September 6, 2015 25. Prager, N., et al., “A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5- alpha-reductase in the treatment of androgenic alopecia,” Jour Altern Complement Med 2002;8:143-52. 26. http://ift.tt/2yHL5mT mtDWQAKVYoAl-ZwxINw 27. Kresser, C. Clinician’s Guide to Thyroid Disease, Kresser Institute;2016:5-6 28. Bussoletti, C., et al., “Use of a cosmetic caffeine lotion in the treatment of male androgenetic alopecia,” Jour of Applied Cosmetology 2011; 29(4):167-79. 29. Berger, R., et al., “The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial,” Brit Jour Dermatol 2003; 149(2):354-62. 30. Fischer, T., et al., “Melatonin increases antagen hair rate in women with androgenetic alopecia or diffuse alopecia: results of a pilot randomized controlled trial,” Brit Jour Dermatol 2004; 150:341-45. 31. A4M Module XIV; Module XXIV: The Nuts and Bolts of Writing Prescriptions for Compounded Medications:The Ultimate in Personalized Medicine: Del Ray Beach, Florida, June 24-26, 2014 32. Maria-Angeliki Gkini, Alexandros-Efstratios Kouskoukis, Gregory Tripsianis,1 Dimitris Rigopoulos,2 and Konstantinos Kouskoukis, Study of Platelet-Rich Plasma Injections in the Treatment of Androgenetic Alopecia Through an One-Year Period, J Cutan Aesthet Surg. 2014 Oct-Dec; 7(4): 213–219. doi: 10.4103/0974-2077.150743 33. Gentile P1, Garcovich S2, Bielli A3, Scioli MG3, Orlandi A3, Cervelli V4., The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial. Stem Cells Transl Med. 2015 Nov;4(11):1317-23. doi: 10.5966/sctm.2015-0107. Epub 2015 Sep 23. 34. Trink A1, Sorbellini E, Bezzola P, Rodella L, Rezzani R, Ramot Y, Rinaldi F., A randomized, double-blind, placebo- and active-controlled, half-head study to evaluate the effects of platelet-rich plasma on alopecia areata. Br J Dermatol. 2013 Sep;169(3):690-4. doi: 10.1111/bjd.12397.
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Silent But Deadly (Shriek - Batman Beyond)
NOTE: Since no colorant was used on this bath bomb (the slightly blue hue comes from the Blue Tansy Essential Oil), it ended up being more fragile than the others and fell apart. Aside from sample sizes, this bomb is currently unavailable.
It also only occurred to me later that I could have used an olive oil carrier and mixed it with garlic, oregano, and thyme essential oils to make a bath bomb that smells like pizza...but who the hell would actually bathe in that?
Yes, I know the connotation for this is a fart, but the bath bomb couldn’t possibly smell any further from the truth!
That said, poor Walter Shreeve was the butt of so many jokes in Terry McGinnis’s rogues gallery and got off to a rough start from his first episode onward. Here’s what we know about him:
He was a very talented, very creative sound engineer with a bright future once.
His ideas seemed so interesting and helpful that he was able to start his own company (Shreeve Sound). This probably means he took out a business loan.
Shreeve Sound was great at designing things, but not so great at selling them. In the end, the company folded and was bought out by Wayne-Powers.
All this, of course, led up to the events of his first episode. In the end, his equipment is used for evil rather than good, his first altercation with Batman results in the loss of his most beloved sense (sound), and he dives deeper into his anger and depression from that point onward.
Walter’s one of my favorite Batman Beyond rogues, since you can watch his descent into villainy bit by bit. With each presence, he gets a little bit worse...but he isn’t as bad of a person as the others.
He treats his assistant Ollie very well and never appears to abandon him. And Ollie apparently thinks highly enough of Walter that he comes back to stick around with him in Where’s Terry.
In prison, Walter continues to invent things that could be used not only for himself, but other people suffering from debilitating hearing disorders. There’s still a large part of him that wants to give back with his talents, not just use them for personal gain.
In a tie-in children’s book, we even see him invent a device to restore a little boy’s hearing after the kid got in the way of a fight between Batman and himself.
All babbling about Walter aside, let’s get into what’s in his bath bomb blend!
Blue Tansy Essential Oil
Ah…one of my favorite Essential Oils!
Blue Tansy comes from (believe it or not) a yellow flower. It gets its name because its oil is a dark navy blue: and even blue enough to color this bath bomb without any additional colorants!
It’s a seasonal plant and one of my more expensive oils (about $60 USD for a 10ml bottle), but definitely one I plan to replenish once I run out.
The smell is reminiscent of German Chamomile, but so much stronger. I call it “Chamomile on Steroids” and is a very useful, versatile oil. It’s a cousin to the daisy flower.
Pros:
Treat fungal infections on your scalp, hair, nail, and skin! Blue Tansy has an antimicrobial and antifungal property. While you can apply it to bruised skin (safely diluted with a carrier oil), it’s never a good idea to put an essential oil neat on a cut, scrape, or wound. Still, if you’re prone to fungal infections, Blue Tansy may be your new best friend!
Treat seasonal allergies (without the grogginess)! Blue Tansy can be diffused to reduce seasonal or other allergies, as it is an asthma-safe oil. It has natural antihistamine properties, but isn’t a sedative. It’s cleared me right up and I’ve had wonderful results with this oil.
Fight aches and pains! Blue Tansy can be massaged into the muscles with a carrier oil to fight tired muscles after a strenuous workout or even the effects of rheumatism or gout. This oil has remarkable anti-inflammatory properties and can dramatically reduce swelling. I’ve even been able to kill a headache with this super-oil before.
Calm your jittery nerves! While Blue Tansy isn’t a sedative oil (like Roman Chamomile), it does have several calming properties. It promotes peace of mind, relaxation, and a more easygoing atmosphere.
Alleviate gastrointestinal discomfort! When applied (with a carrier oil) to the abdomen, Blue Tansy can help you with stomachaches, constipation, abdominal gas, and even menstrual cramps.
Get the perfect skin you always wanted! So long as it’s diluted first, Blue Tansy can be applied to the skin to moisturize the skin as well as kill many of the bacteria and fungi responsible for acne outbreaks.
Cons:
If you plan to purchase this oil, buying Blue Tansy Essential Oil, as opposed to Tansy Essential Oil. Tansy (not Blue Tansy) has a high concentration of the chemical thujone in it. Thujone is a dangerous neurotoxin and will really, really, really mess you up.
Due to Blue Tansy Essential Oil’s high camphor content, people with Parkinson’s or epilepsy should avoid this oil. This also means it is absolutely NOT safe to diffuse around a cat or dog.
There are a whole slew of fake Blue Tansy Essential Oils on the market, so be sure you buy this one from a reputable source. I recommend Plant Therapy.
If you are allergic to daisies, avoid this essential oil.
Blue Tansy Essential Oil should not be used neat (undiluted on the skin) or ingested. Never ingest essential oils without first contacting your physician.
While Blue Tansy Essential Oil is considered safe for use during pregnancy, consult your doctor beforehand just to be on the safe side.
Exercise caution if you are using certain medications (antibiotics, antihistamines, antipsychotics, and antidepressants), as Blue Tansy Essential Oil may interfere with these medications.
Roman Chamomile Essential Oil
There’s actually two true chamomile Essential Oils on the market: German and Roman. Roman is the more potent of the two, so I mixed it into this blend. It worked. I had a pleasant night’s sleep and felt wonderful.
Pros:
It’s one of the safest Essential Oils to diffuse around your kitty! While no Essential Oil is truly safe for a cat and you should always leave the door open so your kitty can escape if you’re using Essential Oils, Roman and German Chamomile are two of the least harmful for your feline friend. Mine loves the smell, so I’m saving up to get it in Hydrosol form.
Fight off insomnia! If you’ve ever had a good calming cup of Chamomile or Sleepytime tea, then you are already familiar with the relaxing properties of Roman Chamomile. This Essential Oil (especially when mixed with other soothing scents like Lavender or Lily of the Valley) promotes a calm, peaceful atmosphere which makes it so much easier to sleep. It works for me, and I’m sure it’ll work for you!
Feeling nauseous due to stress? Fix it with Roman Chamomile! Roman Chamomile can be used for various stress-induced digestive disorders including indigestion, upset stomach, nausea, vomiting, loss of appetite, and bloating from gas.
Chamomile can be a girl’s best friend! A lot of women use Roman Chamomile (especially in tea form) for morning sickness and really painful menstrual periods. It’s considered to be a “blood purifier” and general female tonic, reducing menstrual cramps and better regulating periods.
Relieve pain and swelling! Roman Chamomile is great for reducing pain and swelling of the mucus membranes, sinuses, and joints. It can also be mixed into lotion and applied to the skin for swollen, inflamed areas. It can also be used on wounds, burns, eczema, frostbite, bedsores, hemorrhoids, and diaper rash.
Diffuse it to help your sinuses! Roman Chamomile can be diffused and inhaled for sinus inflammation, hay fever, sore throat (something I’m battling right now), and ear inflammations.
Cons:
Since Roman Chamomile can stimulate a period, pregnant women should avoid this oil to reduce their chances of a miscarriage.
Since Roman Chamomile’s effects on newborns has not been studied, it is best to consider it unsafe for nursing mothers to use.
Roman Chamomile Essential Oil has powerful sedative properties and should not be applied or diffused if you plan to drive, operate machinery, or perform a task that requires your full, complete concentration.
Although Roman Chamomile is good for relieving nausea, too much of it will actually make you more nauseous.
If you have an allergy to ragweed, marigolds, daisies, or similar plants, avoid Roman Chamomile and German Chamomile.
Cedarwood Essential Oil
Cedarwood is one of the oldest essential oils around. The ancient Egyptians and Phoenicians once used it for pigments and medicinal purposes. One whiff of it and it’s really easy to understand why! Cedar is one of the most fragrant woods out there and very calming to the airways.
Pros: Cedarwood is one of the oils considered safer for cats (though hydrosols are still your best bet). As for people, cedarwood can be used to tone the muscles, skin, kidneys, liver, and brain to keep everything in healthy, working shape. It can also be mixed in an astringent and used to remove unwanted microbes from your skin.
Cons: Cedarwood Essential Oil is generally considered to be universally safe.
#Silent but Deadly#Walter Shreeve#Shriek#Batman Beyond Bath Bomb#Bathman Beyond#Batman Beyond#DIY#my stuff#bath bomb#Professor Palmarosa
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