#neuroscienc

[foster-the-world]

Anti-Dopamine Parenting

I'm curious what the research says about this premise and kids with ADHD/autism. My daughters were terrors when I let them watch too much TV when they were little. My son watches a lot more then they ever did partially because 1. He's a lot more difficult to handle so we feel like we need breaks more often 2. He's baby #3 and 3. He's a Covid baby and covid lockdowns brought forth a lot of relaxation in parenting stuff.

Unlike the girls I feel like TV calms him down. In fact, it seems to be the only thing that does. He strongly prefers shows with nonstop action.

I think I'm going to let all three kids turn on the TV as soon as they get home tonight. They are so over tired from the constant stimulation of Christmas stuff. I want their brains to have a break. Luckily, the girls have outgrown the acting terrible when they watch TV thing. Now they are annoying when they fight over what to watch but otherwise fine. They don't watch too much. Baby boy watches too much by my standards but again I think it helps him in some ways??

[warningsine]

TODAY, AN INTERNATIONAL team of researchers shared an extraordinarily detailed atlas of human brain cells, mapping its staggering diversity of neurons. The atlas was published as part of a massive package of 21 papers in the journal Science, each taking complementary approaches to the same overarching questions: What cell types exist in the brain? And what makes human brains different from those of other animals?

With hundreds of billions of cells tangled together, mapping the whole brain is like trying to plot every star in the Milky Way. (The inner workings of each cell are mini worlds of their own.) But just as better telescopes make the universe clearer to astronomers, the analytical tools presented here give neuroscientists “unprecedented resolution looking at brain cells, which will open up new windows for understanding brain function,” says Andrea Beckel-Mitchener, deputy director of the US National Institutes of Health’s BRAIN Initiative, which funded the cell atlas projects.

With a comprehensive map of cell types, understanding how neurons work—and how brain disorders cause them to malfunction—is within reach. “This is a first step towards defining the cellular complexity of the brain,” says Bing Ren, a professor of cellular and molecular medicine at UC San Diego, and a lead investigator on the atlas project. “The results have been nothing but astonishing.”

This isn’t the first brain cell atlas, and it won’t be the last. But it is incredibly detailed. The 21-study collection reports the findings of the BRAIN Initiative’s last five-year funding program, BICCN (BRAIN Initiative Cell Census Network). The NIH allocated $100 million for this endeavor, aiming to catalog brain cell types in more depth than ever before. “The only other large-scale biology problem that we have thought about of this scope is the Human Genome Project,” says Beckel-Mitchener. “The cell atlas project is the biggest team science effort in neuroscience.” 

Historically, it’s been nearly impossible to get a handle on the complexity of the human brain. With so many interconnected pieces, “it’s not really a single organ—it’s like a thousand organs,” says Ed Lein, a senior investigator at the Allen Institute for Brain Science who helped lead the atlas project.

“Prior to this data set, it was just a hypothesis that the brain was really complicated,” adds Amy Bernard, the director of life sciences at the Kavli Foundation, who was not involved in this project. “Now, we can see the cellular diversity and wrap our arms around the problem.”  Neuroscientists often think about the brain in terms of connections between cells, like a wiring diagram. But the brain’s wiring doesn’t say anything about what its individual units are made of. To understand what makes brain cells diverse, Lein says that neuroscientists are borrowing tricks from the genomics world.

All cells within a given brain share the same DNA, but different cells use different sets of genes, which determine what proteins each one makes. This, Lein says, “relates very strongly to all the other properties of the cell,” shaping what it looks like, how it develops, and what other cells it will connect with. 

In an earlier phase of the BRAIN Initiative, scientists developed methods to create a cellular map of the mouse brain. But bringing these tools to human brains is no small feat. Our brains are about 15 times the size of a mouse’s, with a thousand times as many neurons. One major goal of this work was to expand methods used in mice to “create an atlas that tackles the problem of scale,” Lein says.

This was a massive undertaking, relying on collaboration between 250 researchers across 45 institutions worldwide. “People are familiar with big teams like this in fields like astrophysics, but it’s new in neuroscience,” says Bernard. “We took a divide-and-conquer approach,” Ren says, divvying processed tissues from three donated human brains across labs. From there, molecular biologists sequenced DNA, then passed the results off to computational biologists for analysis.

In one study led by Ren, researchers analyzed the molecular switches turning different genes off and on—the internal configuration defining what type of cell a neuron becomes—within more than a million human brain cells. They identified over 100 distinct cell types across 42 different brain regions, far more than the team expected. With this expansive data set, the team trained deep-learning models to read long strings of genetic code and predict how noncoding sequence variants—hard-to-read chunks of DNA that don’t contain instructions for specific proteins—shape cell identity. Ren compares it to reading a book in a foreign language. “Initially, you know nothing,” Ren says. But using a dictionary built with machine-learning tools, “you can start at least making sense of words within that long string of characters.” Many of these gene sequences were indecipherable to researchers before, but their deep-learning model was able to extract hidden patterns and “learn something that our human mind hasn’t yet been able to grasp,” Ren says.  This paper brings scientists closer to being able to identify how someone’s cells work—and how they might falter—from how their genes are regulated. The researchers highlighted several cell types that appear to be strongly linked to neuropsychiatric disorders like schizophrenia and Alzheimer’s disease. They hope that by understanding the brain at this level of detail, they’ll someday be able to trace brain diseases back to their genetic roots, and find treatments that target them. This is “the holy grail for human genetics research,” says Jennifer Erwin, a molecular geneticist and neuroscientist at the Lieber Institute for Brain Development, who was not involved in this project.

While this grail is still out of reach, it’s within sight—and the BRAIN Initiative has years more research queued up and underway. This effort focused on translating methods developed for mouse brains to the brains of humans and monkeys, characterizing cell types, and figuring out what is unique to humans on a molecular level. Currently, many clinical trials fail because they can’t replicate promising results from mouse studies. With a more nuanced understanding of where the brains of mice and humans are alike, and where they’re not, scientists will be better equipped to predict whether a drug will fail in humans before getting too deep into testing.  As much as it reveals, no brain cell atlas can tell you anything about connectivity, or how neurons form networks and communicate across brain regions. Researchers first attempted to create a map of the brain’s neural fiber pathways over a decade ago with the Human Connectome Project, but much more work needs to be done to understand how these connections are formed, how they change over time, and how they generate thought and behavior.

Future BRAIN Initiative programs plan to study neural diversity across humans, but the slate of projects published today did not. Most of these studies analyzed tissue from the same three brains, all donated by neurotypical men of European ancestry. Given the time, effort, and tax dollars required to run experiments at this scale, researchers have to choose between molecular detail and human diversity. “You can either go broad or you can go deep, but you can’t do both at the same time,” Lein says.  Funding agencies like the NIH tend to prioritize the generation of new data over the reuse of existing data, but reusing this data is going to be very important. “Once data is published, it’s not dead. It’s there to be used,” says Bernard. She believes that, now that this massive atlas is online, funding should be funneled to people who want to dig into it—not just researchers who want to add to the pile. “It should be sexy to rediscover things from old data,” she says. Ren’s team made their atlas of genetic switches publicly available, hoping that scientists will mine it to fuel drug discovery, basic science, and clinical research.

These findings lay the groundwork for a new era of neuroscience, where finding personalized treatments for brain disorders is a little less impossible. “Science is somewhat incremental, but people always want to advertise it as groundbreaking,” Bernard says. “This is both.”

[lamilanomagazine]

Milleunanota - Chasing the Future: venerdì al "Sociale" Sergio Cossu, da Matia Bazar a Janacci.

Milleunanota - Chasing the Future: venerdì al "Sociale" Sergio Cossu, da Matia Bazar a Janacci. Cuneo. All’interno del calendario di eventi Chasing the Future, cofinanziati da Comune di Alba, Fondazione CRC e Banca d’Alba, tornano i consueti eventi autunnali organizzati dall’associazione Milleunanota, con due appuntamenti d’eccezione e due di Music On The Bus. Due gli appuntamenti principali. Il primo è per venerdì 20 ottobre al “Sociale”, con l’imperdibile concerto in piano solo di Sergio Cossu, dal 1984 al 1999 tastierista, autore e produttore dei Matia Bazar. Sergio Cossu è un pianista, polistrumentista, compositore, editore e produttore discografico. Ha esordito all’inizio degli anni ’80 come autore per Enzo Jannacci e Miguel Bosé (Sevilla, Amante Bandido) e scrivendo jingle e musiche per teatro, radio, televisione, performance, sonorizzazioni.
È stato componente dei Matia Bazar come tastierista, autore e produttore dal 1984 al 1999. Con la band ha partecipato a quattro Sanremo (Premio della Critica 1985), ha registrato sette album e ha tenuto concerti e apparizioni televisive in tutto il mondo. Tra le sue composizioni più conosciute Ti sento, Souvenir, Noi, Stringimi, La prima stella della sera, Piccoli giganti, Dedicato a te. Nel 2019 ha pubblicato il suo primo disco per pianoforte solo “Falsopiano” seguito da “Aprile” (2020), “Esitazioni” (2021) e “Musica dalla finestra” (2022). Il secondo con un momento innovativo intitolato Musica Scienza, che si terrà domenica 29 ottobre all’Auditorium Palazzo Mostre e Congressi: esperti, giornalisti e musicisti si confronteranno sulle nuove frontiere che le tecnologie aprono per il settore musicale, dai concerti nel metaverso con le relative importanti implicazioni (ad esempio in un’ottica di maggiore fruibilità per le persone con disabilità) alle curiosità mai dette sul mondo dei suoni e della musica. Con la partecipazione della prof.ssa Serena Bovetti del Neuroscience Institute Cavalieri Ottolenghi - NICO e Dipartimento di Scienze della Vita e Biologia dei Sistemi - DiBioS dell’Università di Torino e della LWT3 di Milano. “Anche quest'anno torna Chasing the future con tanti appuntamenti, Music on the bus, appuntamenti in teatro e l’innovativo format Musica Scienza. Quelli pensati quest'anno sono quindi eventi che mantengono le caratteristiche degli anni passati ma cercano di evolversi e offrire curiosità culturali sempre maggiori. Musica, cultura e ambiente sono tutti elementi che fanno parte del nostro percorso culturale”, commenta il direttore artistico dell’associazione Milleunanota Filippo Cosentino. "Oltre ai preziosi appuntamenti in Teatro e al Palazzo Mostre e Congressi, con Music on the bus portiamo letteralmente eventi di qualità nei quartieri per far sì che possa arrivare il clima della Fiera anche fuori dal centro. È una bella sfida che rinnoviamo insieme all’Ente Fiera e a una realtà di qualità come quella di Milleunanota”, sottolinea l’assessore al Turismo e Manifestazioni del Comune di Alba, Emanuele Bolla. Tutti gli eventi sono a ingresso gratuito. Programma Venerdì 20 ottobre h. 21 Teatro Sociale “G. Busca” di Alba Sergio Cossu, dai Matia Bazar a Jannacci: La mia musica fra pop e jazz Dal 1984 al 1999 tastierista, autore e produttore dei Matia Bazar Introduzione a cura del noto critico musicale Alceste Ayroldi e di Adriana Riccomagno, giornalista professionista, presidente Milleunanota Sabato 21 ottobre h. 17 Music On The Bus Giardini Maestri del Lavoro, corso Piave (possibilità di trovarsi in loco o di partire da Alba in piazza Garibaldi alle 16.30 con il bus elettrico di Bus Company dedicato) Lapo Vannucci, Luca Torrigiani “Ricordi di temi italiani e spagnoli per 88 tasti e 6 corde” Domenica 29 ottobre h. 17 Auditorium Palazzo Mostre e Congressi Musica Scienza Musica, ricerca, metaverso e Intelligenza Artificiale Interventi della prof.ssa Serena Bovetti del Neuroscience Institute Cavalieri Ottolenghi - NICO e Dipartimento di Scienze della Vita e Biologia dei Sistemi - DiBioS dell’Università di Torino, dell'azienda innovativa LWT3 e di Filippo Cosentino, direttore artistico Milleunanota e ideatore di Cultura Circolare, metodo di organizzazione eventi sostenibili   Partner tecnici della rassegna: Bus Company, Dragonfly Music Studio, Circolo Acli Collettivo Scaparun 1982, LWT3 Ulteriori informazioni: www.milleunanota.com; Mail: milleunanota.alba@libero.it... #notizie #news #breakingnews #cronaca #politica #eventi #sport #moda Read the full article

[dahlbrendan]

NPR: 4 tips to outsmart dopamine if your kid is hooked on screens or sweets : Shots - Health News

[docdattamd]

Life Coach New York City: Why You Need One

Life can be a journey full of ups and downs, twists and turns, and unexpected obstacles that can throw us off track. It's no secret that life can be challenging, and sometimes we may feel stuck, lost, or overwhelmed with our goals or our current situation. This is where a life coach can be invaluable. In this blog post, we will explore why you might need a life coach in New York City and how they can help you navigate life's challenges.

What is a Life Coach?

Before we dive into why you need a life coach in New York City, it's essential to understand what a life coach is and what they do. A life coach is a trained professional who works with clients to help them achieve their personal and professional goals. They use various techniques and tools to help their clients overcome challenges, develop new skills, and achieve their desired outcomes. Life coaches are not therapists, but they offer their clients guidance, support, and accountability.

Why You Need a Life Coach in New York City

Clarify Your Goals

One of the most important reasons to work with a life coach is to clarify your goals. It's easy to get caught up in the day-to-day demands of life and lose sight of what you want to achieve. A life coach can help you define your goals and create a plan to achieve them. They can also help you identify limiting beliefs or negative self-talk that may be holding you back from reaching your full potential.

Overcome Obstacles

Life is full of obstacles, both internal and external. A life coach can help you identify and overcome these obstacles to achieve your goals. Whether it's a lack of confidence, a fear of failure, or a complicated relationship, a life coach can provide the guidance and support you need to overcome these challenges.

Develop New Skills

Another benefit of working with a life coach is the opportunity to develop new skills. A life coach can help you identify areas where you need to improve and provide you with the tools and resources you need to build those skills. This could be anything from time management to public speaking to conflict resolution. Developing new skills can help you achieve your goals and improve your overall quality of life.

Increase Accountability

Accountability is a critical component of achieving your goals. A life coach can provide the accountability you need to stay on track and make progress toward your goals. They can also help you set realistic deadlines and milestones, which can help you stay motivated and focused.

Improve Relationships

Relationships are an essential part of life, and they can significantly impact our overall well-being. A life coach can help you improve your relationships by providing the tools and resources you need to communicate effectively, set boundaries, and resolve conflicts. Whether it's a romantic, friendship, or professional relationship, a life coach can help you develop healthier and more fulfilling connections.

Enhance Self-Awareness

Self-awareness is essential for personal growth and development. A life coach can help you better understand yourself, your values, and your beliefs. They can also help you identify any negative patterns or behaviors that may be holding you back from reaching your full potential. By enhancing your self-awareness, you can make more informed decisions and create a more fulfilling life.

Why Should You Appoint Dr. Arnab Datta as Your Life Coach in New York City?

Dr. Arnab Datta is an experienced and highly skilled life coach New York City. There are several reasons why you should consider appointing him as your life coach, including:

Extensive Experience - Dr. Datta has over 15 years of experience in coaching, counseling, and therapy. He has worked with individuals from diverse backgrounds and helped them achieve their personal and professional goals.

Multidisciplinary Approach - Dr. Datta's unique interdisciplinary approach to coaching draws from various fields such as psychology, neuroscience, and spirituality. This approach helps his clients better understand themselves and create lasting change.

Customized Coaching - Dr. Datta provides customized coaching to each client based on their individual needs and goals. He understands that everyone has different challenges and works closely with his clients to develop personalized strategies that work for them.

Results-Driven - Dr. Datta is focused on helping his clients achieve tangible results. He provides his clients with the accountability, guidance, and support they need to stay on track and progress toward their goals.

Positive Feedback - Dr. Datta has received numerous positive reviews and feedback from his clients, who have praised his professionalism, expertise, and commitment to their success.

Conclusion

In conclusion, a life coach New York City can be an invaluable resource for anyone seeking personal or professional goals. Whether you're feeling stuck, lost, or overwhelmed, a life coach can provide the guidance, support, and accountability you need to move forward by clarifying your goals, overcoming obstacles, developing new skills, increasing accountability, improving relationships, and enhancing your self-confidence.

[whats-ai]

Towards more general and trustworthy AI + 10 Important Questions for the AI Community. Watch the video: https://youtu.be/3nvAaVSQxs4 With research from Francesca Rossi (IBM Data and AI), Luis Lamb, Daniel Kahneman, Yoshua Bengio, Gary Marcus... IBM posted on Instagram - https://instagr.am/p/CKJcIlqA9HX/

[psychology-job-bank]

Lab Manager for Control and Decision Making Lab at Washington University in St. Louis

We are soliciting applications a lab manager / research technician in our lab. The lab manager will work closely with Dr. Kool to start up a lab studying cognitive control, decision making, and learning. They will be responsible for the general administration of the lab as well as conducting experiments in collaboration with the PI and other lab members. Daily activities will include managing IRB submissions, purchasing, managing finances, programming studies, collecting and analyzing data, revising and editing manuscripts, and supervising undergraduate research assistants. This will be a full-time position that will start in the summer or fall of 2021. The minimum commitment for this job is one year, with the possibility to extend for additional years based on performance and continued funding.

Please see our lab website for more details about the job and how to apply: http://cdmlab.wustl.edu/opportunities

[collageofartsandsciences-blog]

A bi flag neuron for Pride!

[id: an acrylic painting of a neuron on a black background. the neuron is colored like the bi flag: pink, purple, and blue]

[emerysnotebook]

2018.11.19

I’ve gone through more emotional stress this past month than I’ve ever experienced before.  Right now, I’m just trying to regain some control over my life by reestablishing a routine again.  A huge part of my life has disappeared, and I’m trying to find motivation and purpose again.  .__.

[neurosciencenews]

High Intensity Exercise Boosts Memory

The health advantages of high-intensity exercise are widely known but new research from McMaster University points to another major benefit: better memory.

The research is in Journal of Cognitive Neuroscience. (full access paywall)

[bugliest]

purging/repurposing this blog, feel free to unfollow xxx

[irispublisherscancerresearch]

Depression from Sadness to Melancolia - Journal of Neurology & Neuroscience- Iris Publishers

Iris Publishers - Academia.edu | Depression from Sadness to Melancolia - Journal of Neurology & Neuroscience- Iris Publishers 

Sometimes we have felt so sad and so disappointed for a few hours or days, situation that leads us to sleep badly, have awakenings consists before, decreased appetite, easy crying,tiredness, attention deficit, grumpy, even wanting to “swallow the Earth” which is a small thought to “want to die”; These situations are norm-in the mood swings we experience throughout the L day or in a few weeks, and that is recovering with the passage of time, thanks to the adjustment in your brain neurotransmitters experience, we have already commented that they are chemicals in the brain that allow to carry out the different phases of thought.

This series of symptoms or sensations We come from a series of external stimuli or characteristic experiences that all, absolutely everyone must go through once in our lives, as are the heartbreaks,both marital separation and the various breakups of courtship,The loss of A loved one, an economic bankruptcy, A robbery, a job dismissal, anyway. The big problem lies in The Times, that is to say, when this series of situations are presented to the passage of a month, and that they become incapacitated for their work, for their family, for the life in general, this is when it goes from being a moment of sadness to the moment of using the word sounding Depression.

And it is that depression does not respect age, sex, religion,social position or other variant of the human being; It has different presentations because in children we can see it with attention deficit, irritability, unsocial personality or avoids meetings, or kicker or let them hit in school; In adolescents with difficulties sleeping, either with lack or excess, sadness, easy crying, loss of daily habits; Or in elderly people with severe forgetfulness that simulates Alzheimer’s disease.

Read More About This Article  :https://www.academia.edu/38512713/Depression_from_Sadness_to_Melancolia_-_Journal_of_Neurology_and_Neuroscience-_Iris_Publishers

[ozkamal]

New trending GIF tagged animation, gif, loop, illustration, science, pink, blue, lightning, brain, neuroscience, impulse, neuron, electrical, neurons, pink and blue, tom morris, palerlotus via Giphy http://ift.tt/2sYqbge

[divigner-blog]

View this post on Instagram

A post shared by Divigner Group (@divignerweb)

Get your goals game up! #urgentcarecenter #urgentcarecenters #newjerseydoctors #newjerseyphysicians #newyorkphysicians #hospitals #hospital #medicalpractice #physicians #physician #surgery #surgeons #newyorkcitydoctors #newyorkdoctors #specialist #medicine #medical #urgentcare #neurosurgeons #neurology #neuroscienc (at Bloomfield, New Jersey)

[krakenator]

I feel like y’all would appreciate the time a bunch of kids were asking me various brain questions because they found out I'm a neurosciencer. I’m having fun answering some real gems such as “does it go splat when dropped” and “what happens if you store one in whiskey after it was in a car crash three days ago” when one asks “can you eat a brain”

I open my mouth all excited to tell these guys about fucking Kuru disease and my boyfriend at the time beats me to the punch. Gives these kids the full beatdown on this neurodegenerative disease that fucks up your prions

Nighttime comes and I. I gotta know. This question has been preying on my mind for hours now. “hey babe? I know why you might get kuru from eating human brains, but why do you that??”

Turns out he picked it up from me

from pillow talk

[linastudying]

This is a studyblr intro post!

Hi! My name is Lina, I’m 17 and about to be a senior in high school. I have had a studyblr for a while but haven’t posted much, so I changed the name to @linastudying and plan to post more in the future! I’m starting off my blog with a 9 Days of Productivity challenge and hope to post everyday.

What I study:

I’m taking 5 AP classes next year: AP Physics, AP Calculus, AP Literature and Composition, AP Biology, and AP Computer Science. Feel free to message me to rant about these classes :)

I play the harp! I’ll post updates on what I’m practicing now and then.

I spend a lot of time programming and learning new programming languages, so I will probably post about that

I am also learning french

I am taking the ACT and SAT one more time each so I have to study for those

College applications coming up! Expect lots of reblogged masterposts

My interests:

Studying ;)

Harp

Reading

Programming/CS

Robotics

CAD and 3D printing

Bullet Journaling

Cooking and baking

Other fun facts:

My favorite color is purple!

I speak German and English fluently

I love animals

I’m a vegetarian

I plan to be a Computer Science/ Software Engineering major

So there you go, info dump about me! Feel free to message me or send asks. Also I am definitely accepting constructive criticism about how to studyblr (because idk how to studyblr trust me). 

Last but not least, some studyblrs I follow:

@annetellectual, @etudiance, @avocadontstudy, @studyplants , @writtenrain, @unlikelyangel, @neuroscienc, @sootudying, @studylustre