#meglitinides

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Mechanism of Action(MOA)- Meglitinides

In this article we will discuss about the Mechanism of Action (MOA)- Meglitinides. So let’s get started.

Mechanism of Action

Meglitinides bind to the ATP dependent K+ channels on the cell membrane of beta cells of the pancreas in a similar manner to sulphonylureas but have a weaker affinity and faster disassociation from SUR1 binding site. It leads to increase intracellular K+ which causes…