#Nateglinide (Starlix)
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Nateglinide (Starlix)
Nateglinide, commonly known by the brand name Starlix, is an oral medication used to control blood sugar levels in people with Type 2 Diabetes. It belongs to the drug class known as meglitinides, which stimulate the pancreas to produce insulin in response to meals. Nateglinide helps prevent post-meal spikes in blood sugar, making it particularly useful for people who struggle to control their blood sugar after eating.
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How Does Nateglinide (Starlix) Work?
Nateglinide works by stimulating the pancreas to produce insulin quickly after a meal. It acts on the beta cells in the pancreas, helping to reduce blood sugar levels after eating. Its rapid onset and short duration of action make it ideal for managing blood sugar right after meals, especially when combined with other diabetes medications or lifestyle changes like diet and exercise.
Unlike some other diabetes medications, Nateglinide is taken before meals and specifically targets postprandial glucose levels (blood sugar levels after eating). For patients seeking an affordable solution to their diabetes management, DiRx offers Nateglinide at competitive prices with no insurance required. Visit DiRx to find out more.
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When it comes to affordable access to medications, DiRx offers the following advantages:
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Diabetes
Diabetes mellitus, generally known as diabetes, is a metabolic illness that causes high glucose. The chemical insulin moves sugar from the blood into your cells to be put away or utilized for energy. With diabetes, your body either doesn’t make sufficient insulin or can’t viably utilize the insulin it makes.
Untreated high glucose from diabetes can harm your nerves, eyes, kidneys, and different organs.
There are a couple of various kinds of Diabetes :
Type 1 diabetes is an immune system sickness. The invulnerable framework assaults and annihilates cells in the pancreas, where insulin is made. It’s hazy what causes this assault. Around 10% of individuals with diabetes have this sort.
Type 2 diabetes happens when your body gets impervious to insulin, and sugar develops in your blood.
Prediabetes happens when your glucose is higher than ordinary, yet it’s anything but sufficiently high for a conclusion of type 2 diabetes.
Gestational diabetes is high glucose during pregnancy. Insulin-hindering chemicals created by the placenta cause this kind of Diabetes .
An uncommon condition called diabetes insipidus isn’t identified with diabetes mellitus, in spite of the fact that it’s anything but a comparative name. It’s an alternate condition where your kidneys eliminate an excess of liquid from your body.
Each kind of diabetes has extraordinary manifestations, causes, and medicines. Get familiar with how these sorts contrast from each other.
Manifestations of diabetes
Diabetes manifestations are brought about by rising glucose.
General indications
The overall indications of diabetes include:
expanded yearning
expanded thirst
weight reduction
successive pee
foggy vision
outrageous weakness
injuries that don’t recuperate
Manifestations in men
Notwithstanding the overall manifestations of Diabetes , men with diabetes may have a diminished sex drive, erectile brokenness (ED), and helpless muscle strength.
Side effects in ladies
Ladies with diabetes can likewise have side effects like urinary parcel contaminations, yeast diseases, and dry, irritated skin.
Type 1 diabetes
Indications of type 1 diabetes can include:
outrageous craving
expanded thirst
unexpected weight reduction
incessant pee
hazy vision
sluggishness
It might likewise bring about disposition changes.
Type 2 diabetes
Manifestations of type 2 diabetes can include:
expanded craving
expanded thirst
expanded pee
foggy vision
sleepiness
bruises that are delayed to mend
It might likewise cause repeating diseases. This is on the grounds that raised glucose levels make it harder for the body to recuperate.
Gestational Diabetes
Most ladies with gestational diabetes don’t have any manifestations. The condition is regularly recognized during a normal glucose test or oral glucose resilience test that is generally performed between the 24th and 28th long stretches of development.
In uncommon cases, a lady with gestational diabetes will likewise encounter expanded thirst or pee.
The main concern
Diabetes indications can be gentle to such an extent that they’re difficult to spot from the outset. Realize which signs should incite an outing to the specialist.
Reasons for diabetes
Various causes are related with each sort of diabetes.
Type 1 diabetes
Specialists don’t know precisely what causes type 1 diabetes. For reasons unknown, the insusceptible framework erroneously assaults and obliterates insulin-delivering beta cells in the pancreas.
Qualities may assume a part in certain individuals. It’s likewise conceivable that an infection sets off the insusceptible framework assault.
Type 2 diabetes
Type 2 diabetes comes from a mix of hereditary qualities and way of life factors. Being overweight or large expands your danger as well. Conveying additional weight, particularly in your midsection, makes your cells more impervious with the impacts of insulin on your glucose.
This condition runs in families. Relatives share qualities that make them bound to get type 2 diabetes and to be overweight.
Gestational Diabetes
Gestational diabetes is the aftereffect of hormonal changes during pregnancy. The placenta produces chemicals that make a pregnant lady’s cells less delicate with the impacts of insulin. This can cause high glucose during pregnancy.
Ladies who are overweight when they get pregnant or who acquire an excessive amount of weight during their pregnancy are bound to get gestational diabetes.
The main concern
The two qualities and ecological variables assume a part in setting off diabetes. Get more data here on the reasons for diabetes.
Diabetes hazard factors
Certain variables increment your danger for diabetes.
Type 1 Diabetes
You’re bound to get type 1 diabetes in case you’re a kid or teen, you have a parent or kin with the condition, or you convey certain qualities that are connected to the infection.
Type 2 diabetes
Your danger for type 2 diabetes increments in the event that you:
are overweight
are age 45 or more established
have a parent or kin with the condition
aren’t actually dynamic
have had gestational diabetes
have prediabetes
have hypertension, elevated cholesterol, or high fatty substances
have African American, Hispanic or Latino American, Alaska Native, Pacific Islander, American Indian, or Asian American parentage
Gestational diabetes
Your danger for gestational diabetes increments on the off chance that you:
are overweight
are over age 25
had gestational diabetes during a past pregnancy
have brought forth a child gauging in excess of 9 pounds
have a family background of type 2 diabetes
have polycystic ovary condition (PCOS)
The main concern
Your family, climate, and prior ailments would all be able to influence your chances of creating diabetes. Discover which hazards you can handle and which ones you can’t.
Diabetes complexities
High glucose harms organs and tissues all through your body. The higher your glucose is and the more you live with it, the more noteworthy your danger for confusions.
Confusions related with Diabetes include:
coronary illness, cardiovascular failure, and stroke
neuropathy
nephropathy
retinopathy and vision misfortune
hearing misfortune
foot harm, for example, diseases and bruises that don’t recuperate
skin conditions like bacterial and contagious contaminations
melancholy
dementia
Gestational Diabetes
Uncontrolled gestational diabetes can prompt issues that influence both the mother and child. Complexities influencing the child can include:
untimely birth
higher-than-ordinary load upon entering the world
expanded danger for type 2 diabetes sometime down the road
low glucose
jaundice
stillbirth
The mother can foster complexities, for example, hypertension (toxemia) or type 2 diabetes. She may likewise require cesarean conveyance, generally alluded to as a C-segment.
The mother’s danger of gestational diabetes in future pregnancies likewise increments.
The main concern
Diabetes can prompt genuine unexpected problems, yet you can deal with the condition with drugs and way of life changes. Keep away from the most widely recognized diabetes confusions with these supportive tips.
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Treatment of diabetes
Specialists treat diabetes with a couple of various prescriptions. A portion of these medications are taken by mouth, while others are accessible as infusions.
Type 1 Diabetes
Insulin is the fundamental treatment for type 1 diabetes. It replaces the chemical your body can’t deliver.
There are four kinds of insulin that are most normally utilized. They’re separated by how rapidly they begin to function, and how long their belongings last:
Quick acting insulin begins to work inside 15 minutes and its belongings keep going for 3 to 4 hours.
Short-acting insulin begins to work inside 30 minutes and endures 6 to 8 hours.
Transitional acting insulin begins to work inside 1 to 2 hours and keeps going 12 to 18 hours.
Long-acting insulin begins to work a couple of hours after infusion and endures 24 hours or more.
Type 2 Diabetes
Diet and exercise can assist a few group with overseeing type 2 diabetes. In the event that way of life changes aren’t sufficient to bring down your glucose, you’ll need to take drug.
These medications bring down your glucose in an assortment of ways:
Kinds of drug How they work Example(s)
Alpha-glucosidase inhibitors Slow your body’s breakdown of sugars and boring foods Acarbose (Precose) and miglitol (Glyset)
Biguanides Reduce the measure of glucose your liver makes Metformin (Glucophage)
DPP-4 inhibitors Improve your glucose without making it drop too low Linagliptin (Tradjenta), saxagliptin (Onglyza), and sitagliptin (Januvia)
Glucagon-like peptides Change the manner in which your body produces insulin Dulaglutide (Trulicity), exenatide (Byetta), and liraglutide (Victoza)
Meglitinides Stimulate your pancreas to deliver more insulin Nateglinide (Starlix) and repaglinide (Prandin)
SGLT2 inhibitors Release more glucose into the urine Canagliflozin (Invokana) and dapagliflozin (Farxiga)
Sulfonylureas Stimulate your pancreas to deliver more insulin Glyburide (DiaBeta, Glynase), glipizide (Glucotrol), and glimepiride (Amaryl)
Thiazolidinediones Help insulin work better Pioglitazone (Actos) and rosiglitazone (Avandia)
You may have to take more than one of these medications. A few group with type 2 diabetes likewise take insulin.
Gestational diabetes
You’ll have to screen your glucose level a few times each day during pregnancy. In the event that it’s high, dietary changes and exercise could conceivably be sufficient to cut it down.
As indicated by the Mayo Clinic, around 10 to 20 percent of ladies with gestational diabetes will require insulin to bring down their glucose. Insulin is alright for the developing child.
The primary concern
The medication or blend of medications that your primary care physician recommends will rely upon the kind of diabetes you have — and its motivation. Look at this rundown of the different prescriptions that are accessible to treat diabetes.
Diabetes and diet
Smart dieting is a focal piece of overseeing Diabetes . Now and again, changing your eating routine might be sufficient to control the infection.
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TYPE 2 DIABETES: DIAGNOSIS AND TREATMENT
What is Type-2 diabetes?
Type 2 diabetes is a medical disease that influences the way the body metabolizes sugar (glucose)—an essential source of food for the liver.
With type 2 diabetes , your body either resists the effects of insulin — a hormone that regulates the movement of sugar into your cells — or does not produce enough insulin to maintain normal glucose levels.
Type 2 diabetes used to be known as adult-onset diabetes, but today more children are diagnosed with this disorder, probably due to an increase in childhood obesity. There is no cure for type 2 diabetes, but losing weight, eating well and exercising well can help manage the disease.
What may be the symptoms of Type-2 diabetes?
Signs and symptoms of type 2 diabetes tend to develop slowly. In reality, you may have type 2 diabetes for years and you don't learn. Look for the:
An rise in appetite
Frequent discharge
An spike in hunger
Unintentional weight loss
Tiredness
Blurred view
Slow-curing sores
Frequent infection
Areas of darker skin, typically in the armpits and neck
What cause Type-2 diabetes
Type 2 diabetes develops when the body is resistant to insulin or when the pancreas is unable to produce enough insulin. The exact reason for this is unknown, although genetics and environmental factors, such as overweight and inactive, appear to be contributing factors.
Risk factors to the patient of Type 2 diabetes
Factors that may increase your risk of developing type 2 diabetes include:
1) Weight: Overweight is the main risk factor for type 2 diabetes. However, you don't need to be overweight to develop type 2 diabetes.
2) Fat distribution: If you store fat mainly in the abdomen, you have a higher risk of type 2 diabetes than if you store fat elsewhere, such as in your hips and thighs. Your risk of type 2 diabetes increases if you are a man with a waist circumference greater than 40 inches (101.6 cm) or a woman with a waist circumference greater than 35 inches (88.9 cm).
3) Inactivity: The less active you are, the higher your risk of type 2 diabetes. Physical activity helps you control your weight, uses glucose as energy, and makes your cells more insulin-sensitive. The history of the family. The risk of type 2 diabetes increases when your parent or sibling has type 2 diabetes.
4) Race: Although it is not clear why people of certain races — including black , Hispanic, American Indian, and Asian-American people — are more likely to develop type 2 diabetes than white people do.
5) Age: The risk of type 2 diabetes increases as you become older , especially after age 45. This is probably because people tend to exercise less, lose muscle mass, and gain weight as they age.
Diagnosis of Type 2 diabetes
Type 2 diabetes is usually diagnosed with the following:
Test for glycated hemoglobin (A1C). This blood test shows your average blood sugar level for the last two to three months. Normal levels are below 5.7% and the result is between 5.7% and 6.4% prediabetes. A1C level of 6.5 percent or higher in two separate tests means that you have diabetes.
Random test of blood sugar. Blood sugar values are expressed in milligrams per deciliter ( mg / dL) or millimoles per litre (mmol / L). No matter when you last ate, a blood sample showing that your blood sugar level is 200 mg/dL (11.1 mmol/L) or higher suggests diabetes, especially if you also have signs and symptoms of diabetes, such as frequent urination and extreme thirst.
Test of fasting blood sugar. After a night, a blood sample is taken quickly. Less than 100 mg / dL (5.6 mmol / L) is normal. Prediabetes is considered to be prediabetes at a level of 100 to 125 mg / dL (5.6 to 6.9 mmol / L).
If your fasting blood sugar is 126 mg / dL (7 mmol / L) or higher in two separate tests, you have diabetes.
For proper diagnosis of Diabetes, it is important for you to choose best healthcare service providers .
Treatment
Medicines for Type 2 diabetes:
1) Metformin (Glucophage, Glumetza, and others). Metformin is usually the first medication prescribed for type 2 diabetes mellitus. It works by lowering glucose production in the liver and improving your body's insulin sensitivity so that your body uses insulin more effectively.
Nausea and diarrhoea are possible side effects of metformin. These side effects may go away as your body is used to the medicine or if you take the medicine with a meal. If metformin and lifestyle changes are not enough to control your blood sugar level, other oral or injected medications may be added.
2) Sulfonylureas: These drugs help your body to secrete more insulin. Examples include: glyburide (DiaBeta, Glynase), glipizide (Glucotrol) and glimepiride (Amaryl). Potential side effects include low blood sugar and weight gain.
3) Meglitinides: These drugs — such as repaglinide (Prandin) and nateglinide (Starlix)—work like sulfonylureas by stimulating the pancreas to secrete more insulin, but act faster, and their effect in the body is shorter. They are also at risk of causing low blood sugar and weight gain.
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Conclusion
Type 2 diabetes is a chronic, lifelong disease in which blood sugar levels are high. Diabetes is caused by a problem with the way your body makes or uses insulin. Insulin is needed to move blood sugar to the cells where it is stored and then used for energy. People with type 2 diabetes mellitus are taking medicines to improve the body's responsiveness to insulin or to reduce the glucose produced by the liver.
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TYPE 2 DIABETES ORAL & INJECTABLE MEDICATIONS.
There's no one-size-fits-all treatment for type 2 diabetes. American Diabetes Association (ADA),says that the key to managing this increasingly common condition is piecing together a protocol that matches each individual's situation. That said, the weather of treating type 2 diabetes are well-established: lifestyle changes (diet, exercise, weight loss); medications and/or supplementary insulin for people for whom these efforts aren't enough to normalize blood glucose levels; and for a few people, bariatric surgery. This may sound sort of a lot to think about , but the great news is this: When a treatment plan is carefully implemented and followed, type 2 diabetes are often reversed. This isn't an equivalent as cured, but it does mean a lowered risk of complications, and for a few it also may mean the power to wean off medication.
Oral and injectable medications Who Needs Insulin? Lifestyle Changing (or implementing) certain lifestyle practices is almost always the first step of treating type 2 diabetes. A primary goal is to cause weight loss. According to Johns Hopkins Medicine, a loss of just 5 percent to 10 percent of total weight can have a dramatic effect on blood glucose levels in people with type 2 diabetes. Diet Diet is one among the foremost important factors in managing diabetes. It's especially important to scale back carbohydrate intake, which may lead not only to weight loss but also improved blood glucose control and lower levels of triglycerides (a fat associated with an increased risk of heart disease). Although there is no such thing as a politician "diabetes diet," there are a spread of approaches to eating and nutrition that are found to be helpful, including: The Plate Method. This is an easy way to control portions.4 It emphasizes non-starchy vegetables, whole grains, and lean protein—as well as fiber, which can help to slow increases in blood sugar levels—by dedicating specific percentages of the plate to certain foods: one half to non-starchy vegetables (salad, broccoli, string beans, cauliflower, tomatoes, etc.); one quarter to lean protein (three to four ounces of roasted chicken, grilled or baked fish, or lean red meat), and one quarter to complex carbohydrates (for example, quinoa, brown rice, barley, sweet potato, chickpeas or black beans). Room are often made for a touch of healthy fat also (a third of an avocado, as an example , or a teaspoon of olive oil). Carb consistency. Because carbohydrates impact blood glucose quite the opposite macronutrients (protein and fat), taking within the same amount of carbs at each meal will help keep glucose levels steady. This might mean, as an example , sticking to 45 grams of carbs for breakfast and lunch, 15 grams of carbs for a between-meal snack, and 60 grams of carbs for dinner—every day. Limiting foods that dramatically increase blood sugar levels. These include refined, processed carbohydrates, like white bread and pasta; sugar-laden sweets such as cookies, cake, and candy; and fruit juice.1 It's typically fine to eat two or three servings of fresh whole fruit per day. An Overview of Type 2 Diabetes Meal Planning Besides these basic but important guidelines, there's preliminary evidence that dramatically reducing carbohydrates can have a profound and positive impact on type 2 diabetes. In one study, it seen that people with obesity and sort 2 diabetes who followed a really carb-restricted diet for 6 months had lower hemoglobin A1c results and lost more weight than those who followed a reduced-calorie diet.6 Both groups also exercised regularly and had the support of group meetings. This is only one study though: it is vital to consult a dietitian who focuses on diabetes before making major dietary changes. Overview of Dr. Bernstein's Diabetes Diet Exercise Regular exercise is critical for managing type 2 diabetes.1 Physical activity burns calories and therefore contributes to weight loss. But exercise also can have a direct impact on blood glucose control,7 because insulin resistance is closely linked to increased fat and decreased muscle mass: Muscle cells use insulin far more efficiently than fat, so by building muscle and burning fat, you'll help lower and better control your blood sugar levels. The ADA recommends the following exercise guidelines for adults with type 2 diabetes: 150 minutes or more of moderate-to-vigorous aerobic activity per week, cover a minimum of three days, with no quite two days during a row without activity Two to three sessions of resistance exercise on nonconsecutive days per week Two to 3 sessions per week of flexibility and balance training (yoga or t'ai chi , for example) for older adults The ADA also recommends that folks with type 2 diabetes not sit for prolonged periods of your time , and will aim to urge up and move about every half-hour approximately Important 7 Risk Factors for Type 2 Diabetes Quitting Smoking According to the U.S. Centers for Disease Control and Prevention (CDC), people who smoke are 30 percent to 40 percent more likely to develop type 2 diabetes than nonsmokers;8 even using smokeless tobacco can increase diabetes risk. What's more, smokers who have diabetes are more likely to develop serious complications. There is good news that people with diabetes, they stops smoking begin to determine improvements in their diabetes symptoms and overall health benefits soon .8 There are many approaches to smoking cessation; discussing the options with a doctor or certified diabetes educator can home in on one that is most likely to work. Some Practical Tips to chage Lifestyle of Type 2 Diabetes Prescriptions When dietary changes, exercise, and weight loss aren't enough to control blood sugar levels, there are any number of medications that have been developed in the past decade to help. Some methods are oral medications, others are delivered by injection. Most are meant to be used along side diet and exercise, not as a replacement for healthy lifestyle measures. All drugs that follow are approved by the FDA for treating type 2 diabetes. Oral Diabetes Medications Sulfonylureas Sulfonylureas are the oldest class of oral diabetic medications.9 They work by stimulating the pancreas to release more insulin into the bloodstream. tolbutamide tolazamide Diabinese (chlorpropamide) Glucotrol (glipizide) DiaBeta, Glynase (glyburide) Amaryl (glimepiride); also together with rosiglitazone (Avandaryl) and pioglitazone (Duetact) Biguanides Biguanides lower the amount of glucose being produced by the liver while making the body more sensitive to insulin.10 Glucophage (metformin) Glucophage XR (extended-release metformin) Thiazolidinediones Thiazolidinediones sensitize muscle and fat cells to simply accept insulin more readily. These drugs pose certain health risks which will got to be considered before being prescribed. Avandia (rosiglitazone); also combined with metformin (Avandamet) and with glimepiride (Avandaryl) Actos (pioglitazone); also together with alogliptin (Oseni); with metformin (Actoplus Met); and with glimepiride (Duetact) In May 2007, the FDA has issued a security alert regarding the danger of heart attacks and other cardiovascular events when taking Avandia. Both Avandia and Actos have been banned in France and Germany. Alpha-Glucosidase Inhibitors Alpha-glucosidase inhibitors delay the conversion between carbohydrates and glucose during digestion. This helps to regulate blood glucose levels and prevent sugars from peaking too high. Precose, Prandase (acarbose) Glyset (miglitol) Meglitinides Meglitinides help stimulate insulin production when glucose is present within the blood; it isn't as effective if blood glucose levels are low. Prandin (repaglinide); also in combination with metformin (Prandimet) Starlix (nateglinide) DPP-4 Inhibitors Dipeptidyl peptidase-4 (DPP-4) it is an enzyme which destroys incretins—hormones that help the body produce more insulin when needed. DPP-4 inhibitors work by blocking this enzyme. Januvia (sitagliptin); also together with metformin (Janumet) and with ertugliflozin (Steglujan) Onglyza (saxagliptin); also together with metformin (Kombiglyze XR), with dapagliflozin (Qtern), and with metformin and dapagliflozin (Qternmet) Tradjenta (linagliptin); also together with metformin (Jentadueto) and with empagliflozin (Glyxambi) Nesina (alogliptin); also together with metformin (Kazano) and with pioglitazone (Oseni) FDA Warning About DPP-4 Inhibitors, The FDA added a Warning and Precaution a couple of potential side-effect of DPP-4 inhibitors—severe and potentially disabling joint pain. If you're taking a medicine that contains a DPP-4 inhibitor and develop joint pain, let your doctor know directly . You may need to switch to a different medication. Selective Sodium-Glucose Transporter-2 Inhibitors Selective sodium-glucose transporter-2 (SSGT-2) inhibitors lower blood glucose by causing the kidneys to get rid of glucose from the body through urine. Farxiga (dapagliflozin); also together with saxagliptin (Qtern), with saxagliptin and metformin (Qternmet XR), and with metformin(Xigduo XR) Jardiance (empagliflozin); also together with empagliflozin and linagliptin (Glyxami) and with empagliflozin and metformin (Synjardy) Steglatro (ertugliflozin); also together with ertugliflozin and metformin (Segluromet) and ertugliflozin and sitagliptin (Steglujan) Invokana (canagliflozin); also in combination with metformin (Invokamet) A Special Risk With Canagliflozin Canagliflozin features a special warning that taking it can increase the danger of amputation of a toe, foot, or leg thanks to infect. Read the full article
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nateglinide (Starlix) يستخدم ، الآثار الجانبية والجرعة
ما هو nateglinide ، و��يف يعمل (آلية العمل)؟
Nateglinide هو دواء عن طريق الفم يستخدم لخفض مستويات السكر في الدم (الجلوكوز) في مرض السكري من النوع 2. هو في فئة من الأدوية تسمى meglitinides والتي تشمل أيضا ريباكلينيد (براندين). حوالي 90 ٪ من مرضى السكري لديهم مرض السكري من النوع 2. يحدث داء السكري من النوع الثاني عادة في البالغين ويرتبط بالسمنة وتاريخ عائلي قوي لمرض السكري. الأنسولين هو هرمون مهم يتحكم في مستوى السكر في الدم.
مرضى السكري من النوع 2 لديهم القدرة على التحكم في مستويات السكر في الدم. يحدث هذا بسبب انخفاض إفراز الأنسولين من البنكرياس بعد الوجبات ومقاومة خلايا الجسم لتأثير الأنسولين وهو تحفيز الخلايا على إزالة الجلوكوز من الدم. هذا يؤدي إلى ارتفاع مستويات السكر في الدم. يحفز Nateglinide الخلايا الموجودة في البنكرياس لإنتاج الأنسولين بطريقة تشبه فئة العقاقير التي تدعى السلفونيل يوريا ، على سبيل المثال ، glyburide (Diabeta و Glynase و Micronase) ، والتي تستخدم أيضًا في داء السكري من النوع 2. ومع ذلك ، يبدو أن nateglinide يكون له بداية أسرع ومدة عمل أقصر من السلفونيل يوريا. قد تكون الفائدة من هذا التأثير الأسرع والأقصر هو منع الارتفاع السريع والعابر في نسبة الجلوكوز في الدم الذي يحدث عند مرضى السكر مباشرة بعد تناول الوجبة.
اسم العلامة التجارية ل netaglinide هو Starlix.
Starlix متاح في شكل عام.
تحتاج إلى وصفة طبية ل netaglinide.
تمت الموافقة على Nateglinide من قبل FDA في ديسمبر 2000.
ما هي الآثار الجانبية لل nateglinide؟
الآثار الجانبية الأكثر شيوعا للعلاج nateglinide هي:
آخر الآثار الجانبية الهامة للعلاج nateglinide هو نقص السكر في الدم (انخفاض مستويات السكر في الدم مع أو بدون أعراض) يمكن أن يحدث.
بعض أعراض نقص السكر في الدم ما يلي:
جوع،
غثيان،
التعب،
عرق،
صداع الراس،
خفقان القلب ،
خدر حول الفم ،
وخز في الأصابع ،
الارتعاش،
ضعف العضلات ،
عدم وضوح الرؤية ،
درجة الحرارة الباردة،
التثاؤب المفرط ،
التهيج،
الارتباك ، أو
فقدان الوعي.
سؤال
______________ مصطلح آخر لمرض السكري من النوع 2. انظر للاجابة
ما هي جرعة ل nateglinide؟
الجرعة الموصى بها من nateglinide وحدها أو بالاشتراك مع الميتفورمين أو الثيازيدونيد هي 120 ملغ ثلاث مرات يوميًا مع الوجبات. تي
يستخدم 60 ملغ جرعة للمرضى الذين هم على مقربة من هدفهم HbA1c عند بدء العلاج.
يجب أن تؤخذ Nateglinide قبل 30 دقيقة أو أقل من وجبة الطعام ولكن لا ينبغي أن تؤخذ إذا تخطيت وجبة.
Nateglinide متاح في أقراص 60 و 120 ملغ.
يجب تخزين Nateglinide في درجة حرارة الغرفة ، من 15 إلى 30 درجة مئوية (من 59 إلى 86 درجة فهرنهايت) ، في حاوية محكمة الغلق.
ما هي الأدوية أو المكملات الغذائية التي تتفاعل مع nateglinide؟
بدء أو إيقاف الأدوية التالية قد زيادة الاستجابة ل nateglinide وقد تتطلب جرعة من nateglinide ل يتم تخفيض: العوامل المضادة للالتهابات غير الستيرويدية (مضادات الالتهاب غير الستيروئيدية) مثل ايبوبروفين (Motrin ، وما إلى ذلك) ، والأسبرين ومركبات تشبه الأسبرين ، ومثبطات أوكسيديز أحادي الأمين مثل فينيلزين (Nardil) ، والأدوية التي تحجب بيتا مثل بروبرانولول (Inderal). بدء أو إيقاف الأدوية التالية قد يقلل من الاستجابة ل nateglinide وقد تتطلب جرعة من nateglinide لزيادة: الثيازيد مدرات البول مثل هيدروكلوروثيازيد ، المنشطات مثل بريدنيزون ، الغدة الدرقية هرمون مثل ليفوثيروكسين ، والعقاقير المستخدمة في حالات الطوارئ لتنظيم نبضات أو استعادة التنفس عندما يتم حظر الشعب الهوائية. أمثلة على هذه الأدوية الأخيرة هي الإيبينيفرين والألبوتيرول (فينتولين).
هل من الآمن تناول nateglinide إذا كنت حاملاً أو مرضعة؟
لم تجر أي دراسات للسلامة والفعالية عند النساء الحوامل اللائي يتناولن نيتللايند. لا ينبغي أن تستخدم Nateglinide أثناء الحمل.
لم تجر أي دراسات للسلامة والفعالية عند النساء الحوامل اللائي يتناولن نيتللايند. نظرًا لأن العديد من الأدوية تفرز في حليب الأم ، توصي الشركة المصنعة بعدم إعطاء nateglinide للأمهات المرضعات.
عرض الشرائح
مرض السكري من النوع 2 التشخيص والعلاج والدواء انظر عرض الشرائح
استعرض طبيا على 2019/11/08
المراجع
ادارة الاغذية والعقاقير وصف المعلومات.
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Nateglinide belongs to the meglitinide class of blood glucose-lowering drugs
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Starlix 120mg 10pcs
Indications Nateglinide is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. Therapeutic Class Meglitinide Analogues Pharmacology Nateglinide, a nonsulfonylurea hypoglycaemic agent which stimulates insulin release from the pancreatic β-cells by blocking ATP-dependent K channels, depolarising the membrane and facilitating Ca entry…
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nateglinide (Starlix) يستخدم ، الآثار الجانبية والجرعةhttps://t.co/7QS8BcjqlI https://t.co/2QZj1kkbtT
http://twitter.com/ArabmedicalP/status/1194230029548285952
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