#medical type

[thepinkheaded-doctor202]

[velvet-ymarinebloo77]

[springove-rdragon61]

Spring blossom 🌸

Sakura my beloved. 🌸 Long time no Naruto fanart.

Insta ● X

[reasonsforhope]

A new treatment combining ReCET and semaglutide could eliminate the need for insulin in type 2 diabetes, with 86% of participants in a study no longer requiring insulin therapy. The treatment was safe and well-tolerated, and further trials are planned to confirm these results.

Groundbreaking research presented at UEG Week 2024 introduces a promising new treatment approach for type 2 diabetes (T2D) that has the potential to greatly reduce or even eliminate the need for insulin therapy.

This innovative approach, which combines a novel procedure known as ReCET (Re-Cellularization via Electroporation Therapy) with semaglutide, resulted in the elimination of insulin therapy for 86% of patients.

Globally, T2D affects 422 million people... While insulin therapy is commonly used to manage blood sugar levels in T2D patients, it can result in side effects... and further complicate diabetes management. [Note: Also very importantly it's fucking bankrupting people who need it!!] A need therefore exists for alternative treatment strategies.

Study Design and Outcomes

The first-in-human study included 14 participants aged 28 to 75 years, with body mass indices ranging from 24 to 40 kg/m². Each participant underwent the ReCET procedure under deep sedation, a treatment intended to improve the body’s sensitivity to its own insulin. Following the procedure, participants adhered to a two-week isocaloric liquid diet, after which semaglutide was gradually titrated up to 1mg/week.

Remarkably, at the 6- and 12-month follow-up, 86% of participants (12 out of 14) no longer required insulin therapy, and this success continued through the 24-month follow-up. In these cases, all patients maintained glycaemic control, with HbA1c levels remaining below 7.5%.

Tolerability and Safety

The maximum dose of semaglutide was well-tolerated by 93% of participants, one individual could not increase to the maximum dose due to nausea. All patients successfully completed the ReCET procedure, and no serious adverse effects were reported.

Dr Celine Busch, lead author of the study, commented, “These findings are very encouraging, suggesting that ReCET is a safe and feasible procedure that, when combined with semaglutide, can effectively eliminate the need for insulin therapy.”

“Unlike drug therapy, which requires daily medication adherence, ReCET is compliance-free [meaning: you don't have to take it every day], addressing the critical issue of ongoing patient adherence in the management of T2D. In addition, the treatment is disease-modifying: it improves the patient’s sensitivity to their own (endogenous) insulin, tackling the root cause of the disease, as opposed to currently available drug therapies, that are at best disease-controlling.”

Looking ahead, the researchers plan to conduct larger randomized controlled trials to further validate these findings. Dr. Busch added, “We are currently conducting the EMINENT-2 trial with the same inclusion and exclusion criteria and administration of semaglutide, but with either a sham procedure or ReCET. This study will also include mechanistic assessments to evaluate the underlying mechanism of ReCET.”

-via SciTechDaily, October 17, 2024

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Note: If it works even half as well as suggested, this could free so many people from the burden of the ongoing ridiculous cost of insulin. Pharma companies that make insulin can go choke (hopefully).

[irishghosts]

thinking abt a zombie au where simon meets nurse!reader who gets mad at the task force for killing infected. they all think she's fucking crazy but she's not only been locked up in a hospital with no living to talk to since the beginning but she's immune and doesn't know the bites turn people. she's been treating several infected like sick patients the whole time thinking they just need treatement

[springove-rdragon61]

Hubby and Wifey

💋

[creekfiend]

listen i've had to read a hundred other posts with hyperbole and metaphor today and i'm not in the fucking mood

I'll have my butler show you the door

[saturnsocoolioyep]

In the same vein as "I've been taking my medication for long enough that I haven't experienced any symptoms in a while, I must not need to take it anymore! (Spoiler alert: the meds are why you haven't had symptoms)" I present to you a similarly clownish thought process- "I haven't experienced that trigger in a long time, maybe I was just exaggerating how bad it was and it'll be fine to engage with this! (Spoiler alert: take a fucking guess babes)"

[starrysharks]

🤒🩷💙💉

close ups:

+ inspo (literally my fav miku fig ever):

[boimann]

Shoutout to smart videogame men with dark hair and glasses,

I am and forever will be a slut for you <3

[thepinkheaded-doctor202]

Tsunade's will & contempt for losing in Sakura.

[velvet-ymarinebloo77]

[juvian]

“It eats dust in the atmosphere. The composition of the dust determines the color of its core.”

Do not repost!

[nibbelraz]

ive been thinking about the 'mqf finds out sqh is god' thing you said and honestly. i think the best way for it to happen is that someone completely random tells him like 'maybe you should ask sqh for a cure seeing as he made the plant to begin with'. everyone who knew kinda assumed he already did too. this is news to him. tf you mean the most pathetic little meow meow of a martial brother is god. horror violin chord. sqh is already running. adios compadre he knows that the difference between medicine and poison is the dose and believe you him he would make another cure if he could but even 'gods' gotta eat mu-shidi!!!

I AGREE Actually think everyone at An Ding Peak knows very well Shang Qinghua is a God either that he told them or they just worked with him long enough that they went "Hey he DEFINITELY isn't normal" which then spread around towards everyone else and somehow left poor Mu Qingfang out of the loop.

He's unfortunately god, and I don't blame him for what he's going to do to Shang Qinghua once he finds out.

[sierraveree-art]

[reasonsforhope]

"A 25-year-old woman in China is the first person worldwide to have type 1 diabetes reversed through stem cell therapy.

The therapy used the patient’s own cells to create personalized stem cells, which were then used to grow fresh insulin-producing islets.

This breakthrough offers hope for millions with diabetes, potentially eliminating the need for daily insulin injections and reducing complications.

In a groundbreaking medical achievement, a 25-year-old woman in Tianjin, China, has had her type 1 diabetes reversed through a novel stem cell therapy. This marks the first time such a feat has been accomplished globally, offering new hope for millions living with the chronic condition.

The patient, who had been struggling with type 1 diabetes, underwent a pioneering treatment that involved converting her own cells into personalized stem cells. These stem cells were then used to grow fresh clusters of ‘islets,’ the hormone-producing cells in the pancreas responsible for regulating blood sugar levels.

As Nature reports, this therapy’s unique approach of transplanting the newly created islets into the patient’s upper abdomen near her pancreas sets it apart from previous islet transplant methods. This strategic placement allows for easier monitoring via MRI, a significant advantage over traditional liver transplants.

“I can eat sugar now,” the woman said on a call with Nature. After over a year since the transplant, she says, “I enjoy eating everything — especially hotpot.” The woman asked to remain anonymous for privacy reasons.

Experts are astonished at the results, according to Timesnownews. “They’ve completely reversed diabetes in the patient, who was requiring substantial amounts of insulin beforehand,” said Dr. James Shapiro, a transplant surgeon and researcher at the University of Alberta in Edmonton, Canada.

The implications of this breakthrough are far-reaching, as it could potentially revolutionize the way we treat diabetes. By using a patient’s own cells to create personalized stem cells, this therapy bypasses the limitations of donor islet shortages and the need for immunosuppressive drugs, which have hindered the success of conventional transplant methods.

‘If this is applicable to other patients, it’s going to be wonderful,’ diabetes researcher Daisuke Yabe of Japan’s Kyoto University told reporters via Daily Mail.

As the world watches closely, the success of this case sparks hope for the millions of individuals living with type 1 diabetes. It represents a significant step forward in regenerative medicine and paves the way for further research and development in the field."

-via Gadget Review, September 30, 2024