#mc with dcd

[tellodona]

hii, from the heat sensory issues anon (loved it btw)

may i request the brothers with an mc with dyspraxia/DCD? i’ve never seen anyone cover it before so just curious about your take on it and stuff

i'm glad you liked it !

i searched it up and it intrigued me, so let's how this would turn out

the brothers with an mc who has dyspraxia / dcd

heads up: gn!mc, spoilers for lesson 16 in belphie's additional info: dyspraxia or dcd (developmental coordination disorder) is a neurodevelopmental condition that starts in childhood that makes the person have difficult time doing motor skills (such as walking, closing your buttons on a shirt, etc.)

lucifer

informed beforehand through your files

at first, only helped you for diavolo's reputation, but now helps you willingly

your uniform is closed with a zipper, he doesn't require you to wear a necktie (but if you want to, he'll make sure he'll be help you or have one of his brothers do when you want the help)

takes you out on short walks to help you get accustomed to the newer environment that is the devildom

obviously gives you easier tasks or chores, but if you want to help out more, he'd supervise you

"mc, let me help you with that" "mc, you shouldn't carry such heavy things. please, let me" "mc, put that broom down right now or so help me-"

helicopter mom

mammon

the info about you is basically drilled into his head

he has to ask satan what dcd means though

at first, he's annoyed that he has to babysit a clumsy human, because how can you be such a klutz? are you stupid-

he absolutely pampers you the next day

he'll have your arm hooked around his whenever you walk together, insisting that you need all the help you get

would still want to include you in his shenanigans, but has been choosing the easier things whenever he's with you

"human, the floor's slippery, hold my hand" "'c- course i'm only doing this because i need to, alright?! don't go getting the wrong idea!" "mc, forget that assignment and hang out with me! me! you're only getting your back strained the longer you sit there!"

he'd purposely get lazy with his tasks just to hang out with you

leviathan

doesn't care at first

"normies and their weaknesses"

he felt like an idiot for how he acted back then

he finds you characters that you can kin

"hey, you know about-"

he ends up ranting up to 3 hours about whys and hows you and said character are the perfect mirror

doesn't know how he'd be able to help you tbh, but he'd probably serve as a crutch for you if you need one

"mc... are you supposed to carry that?" "i don't know about this one, mc..."

he would sew you easier to wear clothes though

satan

has studied that human condition before, at least

so when the human exchange student living with them had it was a surprise and a big coincidence

he really wouldn't bother with you at first, just starting with the "do you need help?" questions just to be polite with you

later on he'd help you without even asking

he'd tie your necktie, your shoelaces. heck, even your hair if it's long enough so it wouldn't get in the way of your eyesight

he's read physical therapy might help, he'd be taking you on short walks too. even letting you help out in the kitchen for little tasks like putting the onion on the stove

"oh, mc. care to help me in the kitchen? you can wash the bat wings this time" "hm, this might be too hard for you. no, don't even try to deny it"

helicopter mom 2

asmodeus

he'd coddle you too much at first tbh

he'd stop if you express distaste or that you're uncomfortable

that wouldn't stop him with helping you around, though. at some point

"oh, mc, mc! let's get beel to carry this, shall we? we're both so frail and i wouldn't want us both to get hurt!"

he'd probably have a few remedies that he thinks might help you, but would consult lucifer or satan first if they're safe for humans

"mc, dear! i found this lotion that might help you! don't worry, lucifer says it's 100% safe!"

"i didn't say it's a hundred percent safe, asmo."

"oh, hush!"

would give you massages

beelzebub

he'd think you're completely paralyzed at first

so the first thing that occurred to him was to put you on his shoulder the first time you two met

"don't worry, lucifer. i can carry them"

"beel, no-"

eventually puts you down after much convincing that you're not a fragile doll

thinks you might get stronger if you eat a lot

"mc, try this one"

absolutely hovers over you and always carry everything you have

"mc, let me do it" "mc, the door's too big for you to push open" "mc... maybe you'd be safer on my shoulder"

he's reminded of the times he used to coddle someone else in the past (that isn't belphie)

belphegor

not only are you stupid, you're stupidly fragile

^ his thought on you during his time at the attic

you were so easy to manipulate, so when he got his hands around your neck-

he wants to stop thinking about that

he avoids you for the most part, thinking he'll hurt you again

you'd have to initiate an interaction with him if you want him to talk to you

when you do, he'd keep a safe distance, but keeps an eye on you if you looked weaker as the day goes on

he'd make sure you'd have the most peaceful dreams so you'd be energized in the morning

he's the literal avatar of sloth, it'd be a miracle if he'd do anything with you

"mc, just leave that alone. let lucifer find it or something" "mc........ let's go back to bed" "mc, i want to bestow the sin of sloth on you just so you would stop moving around so much"

don't use him as a crutch, chances are you'll both fall to the floor

i love them you guys

[nhanhshopaudio]

Kế thừa thành công từ huyền thoại DL-103

Kế thừa thành công từ huyền thoại DL-103

Bên cạnh những sản phẩm đình đám như đầu CD DCD-A110, ampli tích hợp PMA-A110 hay AV Receiver AVR-A110, Denon còn mang tới cho người chơi mâm đĩa than một món quà đặc biệt nhân dịp kỷ niệm 110 năm thành lập công ty: kim MC DL-A110. Trong những năm gần đây, sự trở lại của đĩa than đã khiến thị trường mâm đĩa trở nên sôi động hơn, cải thiện doanh thu đáng kể cho những thương hiệu nổi tiếng bao gồm…

[hawkbucks]

I would love to have a comic store of my own but I know that’s a far off, near unobtainable dream for me so I have decided to live vicariously through my comic shop AU. 

[askcarla]

I think Carla used to be pure too pure he it was difficult to love and understand him because he was pure and clueless about. emotions to the point he come off as. unintentionally insensitive especially towards shin lol but was regardless loved. and admired for it he was not only the. strongest and wisest and most capable but. he had a charisma u can't help but want to. help him u could tell he was sincere and very. devoted to the well being of his clan u can't help but want to support him and. acknowledge his hard work and dedication to his clan well at least before the df .

and of course there was some that was envious of him being so loved and capable.

Df he became a sadistic vengeful bitter brute due to learning all of that from his dad that took pleasure in tormenting others to. achieving his goals especially towards yui to the point I was glad mene and his mom wasn't there to meet him .

I wonder how they and his clan members that supported and admired him would react if they saw how he changed in his df self. that he was no longer the once more pure dedicated wise and caring ruler and became. someone who will humiliate and toture people to force them to obey him instead of him formerly ruling through gaining the. support of others with his wise dedicated charisma i think they would be horrified (;_:).

Just look at how messed his relationship was with shin by df he didn't even hesitant to try and kill him when he had the chance(╥﹏╥) .

Le/cl he was like completely different person he was more like his original personality except he more sweet ,possessive ,horn*of. yui really good and wise husband and king and nice to his bro the only thing I don't like was when he tried to dominated yui into only. loving him and touching him when he. was jealous but I forgive him because he sweet and was so lonely for a unimaginable amount of time.

K: I mean—...Come on bro, if Brute Change wouldn't be a dark shit, then what's the point to call it 'Brute'!?!?

Carla Tsukinami is a character, who is Logician (INTP). Pretty sure so is Ruki?? I can understand these kind of character's approach because I personally kinda same too, struggle a lot with emotions.

Due to being so much determined on everything, and not being that much into feelings or emotions, he is quite insensitive.

It is true, and his whole DF route was a struggle for MC, helping Carla gaining that emotional feelings, out of his bounded and strict logic stuffs, like he was born to king and he needs to be perfect for that, is fact. But the feelings say he do not need to be too strict for it.

And I honestly enjoyed his whole route of DF, overall endings too. Carla himself mentioned he wasn't jealous (envy?) of Shin, he just wanted to be praised by his father. Even if once. He apparently fell in love with Yui in maniac I assume, he was not just sure about that feelings, that is why he might tried to ignore always thinking those are absurd. Like even u see, Carla did not even understand the love between Krone and Giesh! So yea, in short, his DF plot was basically these, bringing out that 'feelings' of Carla from logics.

And for Shin, all I will say—he loved his brother, he appreciated him and u can see that in Shin's route. I think the brute endings were just a misunderstanding, sadly. And i did not find that 180 degree in his characteristics changing. A friendly reminder that HEAVEN things count too. Considering that, it is ok, his typing regardless. Same for CL, since it took place before LE, so less character development. Same goes for DCDS too! Overall I'd say, it was not that 180 degree turn.

[lifeofkaze]

Happy DCD bestie 😂😂 so, we know that Director’s Cut is the best ask game. It’s your favourite, it’s my favourite… so let’s have the director’s cut on Favourites! 💛

Gotta love DCD bestie 💛

And also gotta love Favourites! So, let's talk about it.

'Favourites' was actually the first fic request I ever got. I was really surprised to find it in my inbox because I never really said I'd do requests but I had A LOT of traffic on my blog after writing 'The Easter Dragon' and I didn't mind at all - I was so flattered by it, in fact. The thought that someone loved my writing so much they wanted me to write their idea into existence? Crazy! 😱💛

Anyway, when I read the prompt I knew immediately what I wanted to happen. If there's one thing Charlie is very secure in himself over it's dragons after all, and I liked the idea of switching between a very self-conscious Charlie and a Charlie who absolutely knows his shit. Because people being passionate about something is really attractive, I thought maybe it's not even just Charlie crushing on the MC, but vice versa and decided to give them both this cutesy, shy attitude towards the other.

While the story basically wrote itself, what took longest about it was definitely all the research on the dragon species. Honestly, I spent twice as long reading about them and jotting down their characteristics than I spent writing this fic. Damn Potter Wiki wormholes...

The flashcards idea actually came from the brilliant story "The Girl Who Vanished" by @nevilles-top I was catching up on at the time, where the main character Ana uses flashcards to get a grip on her HoM class. I loved the idea and I always thought Charlie was good at sketching, so I let him build his own stack of cards with pretty pictures attached.

What will never stop amusing me is how everyone seems to love the small mention of Charlie's dimples most. I didn't even think about this, it was just a random off-hand thought I had so I wrote it in. I love that it even made it into your brilliant canon!

And now that I reread the short to better answer your ask, I have to say... I can actually see this short happening between Charlie and Ava before they became a couple. I don't have that many headcanons about their time before 'Larger Than Life' other than what is featured there (and some things you'll see in a future AoB bonus chapter), so yeah. Who knows?

[millepara]

byekatsu (friends?)

so it seems like there’s going to be some kind of big aikatsu announcement today. the DCD game twitter says to “look out for a lot of updates” today, and more tellingly, the anime twitter says that instead of the normal card mini corner at the end of the ep, there’s “something else☆”.

like everyone else, I suspect strongly that the announcement is the end of Kagayaki no Jewel at the very least (ie the start of the Wakaba Generation), or a totally new series starring the game spoiler girl. personally I really hope that it’s the former, because a new series would mean massive changes to the game, including losing all the hard work I’ve done leveling Milk up for the last year and a bit. (that might still happen with a MC switch, but at least there’s less of a chance that way...)

more than anything I’m going to be really sad about Honey Cat and Reflect Moon being casualties of whatever happens next, but I’ve been really sad about that for about the past week since I confronted this whole thing, so what’s new. neither of them were my most fav aifriends idols ever, but Honey Cat had my fav Friends dynamic and my fav Friends song (You x Me), and I really enjoyed stealing Reflect Moon’s entire aesthetic for Midnight†Fairytale, haha. mostly I don’t want to see any characters get neglected, and I’m sad they’re not going to get JLRs. (that’s not speculation--when you finish the Topaz challenge, Hibiki shows up to congratulate you on collecting all of the jewels. there’s no more. I genuinely believe there were plans for all the idols to get JLRs at some point--like, remember that opening scene of all the different rays of light spreading around the world? the one that matched the colors of all the jewels in the dcd jewel frames etc?--but they had to scrap them and cut aifriends short for whatever reason.)

I have a lot more to say, but I think wasting my time with unfounded speculation when we’re literally 3 hours out from finding out what’s up is probably not the best idea. I’ll be back later with translations of whatever the news is.

[actionfigureinsider]

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Jack Skellington Awakens as a PREVIEWS Exclusive Master Craft Statue (BALTIMORE, MD) — (October 24, 2019) — Who better to usher in the Holidays than Jack Skellington the Pumpkin King himself?!

[syupii]

2019/11/2(土) DMM VR THEATER 横浜

「アイカツ! LIVE★イリュージョン　〜3大チーム!ドリームマッチ♪ アンコールParty!2017 DMM VR THEATER Final」

ナイトタイム　チームI セットリスト

※うろ覚え

1.「START DASH SENSATION」(あかりちゃん、スミレちゃん、ひなきちゃん、ののっち、リサっぺ)

スノーイリュージョンコーデ(Team M、Team I、Team A)

2.「Signalize!」(いちごちゃん、あおい姐さん、蘭ちゃん、おとめちゃん、ユリカ様、さくらちゃん、かえでちゃん)

スノーイリュージョンコーデ(Team M、Team I、Team A)

3.「フレンド」(凛ちゃんとまどかちゃん)

まどかちゃん:パステルパレードコーデ

凛ちゃん:ネイビーパレードコーデ

4.「Sweet Sp!ce」(2wingS)

いちごちゃん:エンジェリージェミニコーデ

セイラちゃん:スイングジェミニコーデ

5.「チュチュ・バレリーナ」(ダンシングディーヴァ)

スミレちゃん:ディーヴァナイトコーデ

凛ちゃん:ダンシングナイトコーデ

☆MCでいちごちゃんとあかりちゃんと美月さんがチーム紹介。

チームA

リーダー:あかりちゃん

ルミナス、バニチリペパ、ノリノリシスターズ

チームI

リーダー:��ちごちゃん

ソレイユ、ぽわプリ、ドリアカ

チームM

リーダー:美月さん

トライスターとWM

「※投票は受け付けておりません。」のテロップで会場のみんな笑い。

6.「Chica×Chica」(バニラチリペッパー)

珠璃ちゃん:チリゴールドコーデ

まどかちゃん:バニラゴールドコーデ

凛ちゃん:ペッパーゴールドコーデ

※アクセは無し。

7.「Angel Snow」(ぽわぽわプリリン)

おとめちゃん:ドリーミーキャンディコーデ

さくらちゃん:ライムキャンディコーデ

しおんちゃん:ブルーキャンディコーデ

コメントはおとめちゃん。

8.「Take Me Higher」(トライスター)

美月さん:マゼンタトリオコーデ

かえでちゃん:イエロートリオコーデ

ユリカ様:シアントリオコーデ

コメントはユリカ様。

⭐︎投票タイム

3チームとも同点。

9.「笑顔のSuncatcher」(WM)

美月さん:サマーデイムーンコーデ

みくるさん:サマーデイミラクルコーデ

10.「KIRA⭐︎Power」(セイラちゃん、きいちゃん、そらちゃん)

セイラちゃん:ルージュドリームコーデ

きいちゃん:ライムドリームコーデ

そらちゃん:スカイドリームコーデ

マリアちゃん:アプリコットドリームコーデ

11.「ダイヤモンドハッピー」(ソレイユ)

いちごちゃん:スターサンシャインコーデ

あおい姐さん:スターサンライズコーデ

蘭ちゃん:スターサンセットコーデ

12.「lucky train!」(ののリサ)

ののっち:ベイビーデビルコーデ

リサっぺ:シークレットデビルコーデ

13.「Pretty Pretty」(ルミナス)

あかりちゃん:グレイスフォックスコーデ

スミレちゃん: ヴァイオレットハッターコーデ

ひなきちゃん: ゼペットイノセントコーデ

※アクセ無し。

14.「恋するみたいなキャラメリゼ」(みやびちゃん、ここねちゃん、ニーナちゃん)

ここねちゃん:キャンディハウスコーデ

みやびちゃん:カラフルフォーチュンアクセ+グレーテルフラワーコーデ

ニーナちゃん:パステルパニックコーデ

15.「アイドル活動!」(いちごちゃん、あかりちゃん)

いちごちゃん:ハイピンクパレードコーデ

あかりちゃん:ピンクパレードコーデ

☆ファッションショー

司会はジョニー先生。登場アイドル全員ブランドスターコーデ。

・エンジェリーシュガー

いちごちゃん&まどかちゃん:エンジェリースターコーデ

・フューチャリングガール

あおい姐さん&しおんちゃん:フューチャリングスターコーデ

・スパイシーアゲハ

蘭ちゃん:アゲハスターコーデ

・ハッピーレインボー

おとめちゃん:ハッピースターコーデ

・ロリゴシック

ユリカ様&スミレちゃん:ゴシックスターコーデ

・オーロラファンタジー

さくらちゃん&マリアちゃん:オーロラスターコーデ

・マジカルトイ

かえでちゃん&きいちゃん:マジカルスターコーデ

・ラブクイーン&ラブムーンライズ

美月さん:ムーンライズスターコーデ

・スイングロック

セイラちゃん:スイングスターコーデ

・ボヘミアンスカイ

そらちゃん:ボヘミアンスターコーデ

・ドリーミークラウン

あかりちゃん:ドリーミースターコーデ

・ヴィヴィッドキス

みくるさん&ひなきちゃん:ヴィヴィッドスターコーデ

・サングリアロッサ

珠璃ちゃん:サングリアスターコーデ

・ダンスフュージョン

凛ちゃん:ダンススターコーデ

・桜色花伝

みやびちゃん:桜色スターコーデ

・レトロクローバー

ここねちゃん:レトロスターコーデ

・ドーリーデビル

ののっち&リサっぺ:ドーリースターコーデ

・メチャパニック

ニーナちゃん:パニックスターコーデ

☆MCはののリサ。ここからはソロライブ。

16.「輝きのエチュード」(いちごちゃん)

いちごちゃん:リラフェアリーコーデ

17.「prism spiral」(あおい姐さん)

あおい姐さん:天の川コズミックコーデ

18.「硝子ドール」(ユリカ様)

ユリカ様:ゴスマジックコーデ

19.「MY SHOW TIME!」(凛ちゃん)

凛ちゃん:ソウルマリオネットコーデ

20.「Du-Du-Wa DO IT!!」(あかりちゃん)

あかりちゃん:オデットスワンコーデ

※髪型は4年目。

21.「Let’s アイカツ!」(ルミナス)

あかりちゃん:ホワイトスカイヴェールコーデ

スミレちゃん:ブルーエンプレスコーデ

ひなきちゃん:ストリートアートコーデ

22.「オリジナルスター☆彡」(いちごちゃん、あおい姐さん、蘭ちゃん、美月さん、おとめちゃん、ユリカ様、さくらちゃん、かえでちゃん)

いちごちゃん:シュガーリボンコーデ

あおい姐さん:シュガープラネットコーデ

蘭ちゃん:シュガーバタフライコーデ

美月さん:シュガームーンコーデ

おとめちゃん:シュガーキャンディコーデ

ユリカ様:シュガーバットコーデ

さくらちゃん:シュガーフラワーコーデ

かえでちゃん:シュガーバルーンコーデ

23.「SHINING LINE*」(ルミナスとソレイユ) ※フル

あかりちゃん:アルメリアプリズムコーデ

スミレちゃん:ライラックプリズムコーデ

ひなきちゃん:マーガレットプリズムコーデ

いちごちゃん:スターサンシャインコーデ

あおい姐さん:スターサンライズコーデ

蘭ちゃん:スターサンセットコーデ

⭐︎アンコール

　スクリーンにメッセージが写し出された。アイカーツ!」と言ってほしいとお願いされ、みんなで叫んだ。

24.「Lovely Party Collection」(いちごちゃん、美月さん、ユリカ様、みくるさん、あかりちゃん、凛ちゃん、まどかちゃん、ここねちゃん)

※2014年のDCD版アイカツ8のメンバー

チアフルパステルコーデ

25.「カレンダーガール」(ソレイユ)

いちごちゃん:オーロラキスコーデ(アクセ無し)

あおい姐さん:プリズムサイバーグラフィックコーデ

蘭ちゃん:アゲハコーデ

26.「ダイヤモンドハッピー」(ソレイユ)

いちごちゃん:サンシャインコーデ

あおい姐さん:サンライズコーデ

蘭ちゃん:サンセットコーデ

27.「SHINING LINE*」(いちごちゃん、あおい姐さん、蘭ちゃん、ユリカ様、美月さん、あかりちゃん) ※曲はうろ覚え

いちごちゃん:オーロラキスコーデ

あおい姐さん:天の川コズミックコーデ

蘭ちゃん:ローズボンボンコーデ

ユリカ様:ゴスマジックコーデ

美月さん:ロイヤルムーンコーデ

あかりちゃん:ホワイトスカイヴェールコーデ

出演アイドル全員登場して挨拶。

☆この後にらきちゃんがアナウンスで登場。あいねちゃんとみおちゃんも。

28.「アイドル活動! オンパレードVer.」(いちごちゃん、あかりちゃん、ゆめちゃん、あいねちゃん、みおちゃん、らきちゃん) ※新作

いちごちゃん:ハイピンクパレードコーデ

あかりちゃん:ピンクパレードコーデ

ゆめちゃん:ピンクマーチングコーデ

あいねちゃん:ピンクリンクコーデ

みおちゃん:ブルーリンクコーデ

らきちゃん:パステルパープルラインコーデ

[tellodona]

hello hiii dcd anon (i’ll just use 🤡 anon from now on its easier) here, i hope i’m not making too many requests i’m very sorry if i am

a thought i’ve had for like a while is how demon skin works like, i feel like it’s less stretchy and soft to the touch than human skin because demons are simply just tougher, and also it heals faster. so what i am trying to get at is that demons probably don’t have like stretch marks? it rarely gets to a point their skin would do such a thing and even if it does it heals very fast so it’s not ever acknowledged.

so what about mc with like an abundance of stretch marks? like i can somewhat confidently say at least 15% of my body is just purple lines everywhere so i wonder how would the brothers react to that? once again sorry if i’m doing too many requests

it's alright ! all your requests are so fun to do so don't feel bad about them ! they're topics that i really like learning about

the brothers with an mc who has stretch marks

heads up: gn!mc, hc that demons and angels alike get stretch marks when overworking

lucifer

is probably curious about it

"so you're telling me humans don't smoothen out their skin easily? i see, i see"

probably doesn't even care, if you're still alive even with that abundant of stretch marks, there shouldn't be any problems

he might think it's a condition you're not telling him though

he'll try to rub pride on you if you're insecure about them

you're great just the way you are, mc. your appearance isn't going to change the person you are today

mammon

"what the hell happened to ya?????"

pretends he isn't worried, but he totally is

he'd ask a lot about how you got them because as far as he knew, demons get them when doing lotsa strenuous work

so at first he'd say you're stupid and to stop overworking

when you probably tell him it's not because of that he blanks

he'll understood soon enough

but he'll bark at people who'd look at you weirdly

leviathan

he raises an eyebrow at you

dang, what happened?

wouldn't speak it out though, afraid you're insecure and you'd dislike him

if you're self-conscious about it and see someone with "better" skin than you, he'd feel envy off of you right off the bat

he'd try to comfort you as much as he can

he likes sewing, so if you're insecure, he'd sew some clothes for you to make you feel better and look "prettier"

you're already pretty/handsome/great/awesome/good in his eyes, mc

satan

"i've read humans don't heal easily like demons, but i didn't expect this..."

he didn't mean it in a bad way, though. he'd have to assure you, he's just curious

he thinks it makes you prettier, because it's unique on you

encourages you to accept yourself, because these don't make you less beautiful

he turns demons who make fun of you into shreds behind your back

asmodeus

oh, sweetheart! those marks look so beautiful!

this man sees art in everything, so it's like seeing some intricate designs on your body, and he absolutely loves it

he offers you some soothing lotions though, because he knows they're not normal

if you're insecure about it, he'll absolutely fight you because honey, you're so beautiful!

you shouldn't think that way, it makes him sad

spa days bi-weekly to help soothe your marks

he destroys every demon's social lives when they make fun of you even just once

beelzebub

oh, you have marks, mc?

he sometimes gets them when he exercises a lot, so it's nothing new to him

but why aren't they going away for you

oh right, you're human

you look nothing different to him, anyway, it doesn't matter to him

he'd eat the people who'd look at you wrong

belphegor

this is why you should always nap with him, mc, now look, you've got marks-

oh, they've always been there on you?

he'd grimace since he sees stretch marks as a sign of lack of sloth, but he wouldn't judge you

would always use it as an excuse to cuddle with you though

demons looking at you wrong? eternal sleep, it is

IM SO SORRY THIS TOOK SO LONG I WAS SO BUSY :SOB: IM SORRY THEYRE SHORTER TOO RGAHH

[lupine-publishers-acr]

Lupine Publishers | The Current Status of Continuous Flow Left Ventricular Assist Devices

Abstract

In this review, we hope to give a perspective of the new realities of cardiac mechanical circulatory assist devices. New iterations of devices are providing greater durability and freedom of complications. Work is near to provide internal batteries and transcutaneous energy transfer systems for completely implantable systems, avoiding the need for an externalized drive line.

Keywords: Heart Failure; Transplantation; Mechanical Circulatory Support

Twine and Twine or Lose the Plug- Dislodged Left Atrial Appendage Closure Device

In patients with severe heart failure, cardiac transplantation has been shown to provide considerable benefit. Since 1967, in excess of 88,000 total heart transplants have been performed and 1-year survival is 81%, the annual mortality is 4% per year thereafter. The supply of donor hearts is incredibly limited and much research has focused on mechanical means of improving myocardial function, and several such left ventricular assist devices (LVADs) have been developed through the National Institutes of Health artificialheart program. Several devices have been previously approved by the Food and Drug Administration as bridging therapy to transplantation, though none have been studied as long-term alternatives to transplantation. The Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure (REMATCH) [1] trial explored whether a specific type of LVAD (a previous generation pulsatile device), when used in the long-term, would reduce mortality (Figure 1). The survival following severe heart failure was extremely poor in the optimally medically treated group in this trial (defined as End-stage heart failure was defined as New York Heart Association (NYHA) class IV symptoms for at least 90 days, left ventricular ejection fraction (LVEF) <25%, peak oxygen consumption <12 mL/kg/min or continued need for intravenous inotropes for symptomatic hypotension).

In the optimally medically treated control arm of the Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure (REMATCH) trial [1] which evaluated an externalized pulsation ventricular assist device, survival at one year was 28% and 6% at two years, underlying the poor prognosis of this clinical entity (Figure 1). Driving the need for mechanical circulatory support (MCS) is the relative paucity of donors and the unmet need for orthotopic heart transplantation in the general population. There has also been an increase in the number of patients who require mechanical circulatory support (MCS) as a bridge to transplantation [2]. This has been driven, particularly in the UK by limitation of the number of hearts for donation, and also to buy time on the transplant waiting list. This is due to an increase in the numbers of non-heart beating donors (DCDs), whereby retrieval takes place in a circulation arrested donor, and the increased survival of head injury patients and those with intracranial bleeds who are treated by a decompressive craniotomy, reducing the pool of donors who have raised intracranial pressure and who have coned, resulting in brain stem death. The net result is a retrieval rate for heart transplantation of around 19%. The risk of having preformed antibodies directed against the donor heart (sensitised patients) is increasingly likely and is particularly challenging as it may increase the risk of rejection and allograft vasculopathy. There has also been an increase in the number of patients requiring MCS as a bridge to transplantation [3]. This allows many severely ill adults and paediatric patients to survive until a suitable donor heart is available. Patients with MCS are at increased risk for rejection, infection, stroke, and bleeding. The need for transfusions also increases the risk of pre-sensitization [3-5]. Survival at 1 and 5 years is decreased in patients requiring MCS prior to transplantation, but still higher than 80% and 70%, respectively (ISHLT database) [2].

Figure 1:  Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure (REMATCH) trial (Rose et al N Engl J Med 2001; 345:1435-1443).

Advances in Donor Allocation and Selection

Recipient criteria for heart transplantation include, severe symptoms despite maximal medical management, the absence of reversible or surgically amenable heart disease, and where estimated 1-year survival is less than 50% [6]. An estimate of functional capacity in ambulatory patients can be best quantified by measurement of peak O2 consumption (VO2max). Patients with low VO2max (<12 ml/min/kg) have high mortality even if treated with beta blockers and transplantation should be considered for these patients. In addition, heart failure prognosis scores to estimate survival, such as the Heart Failure Severity Score may be used. This calculates a survival probability on the basis of the presence of ischaemic cardiomyopathy, resting heart rate, left ventricular ejection fraction, mean blood pressure, interventricular conduction delay, VO2max and serum sodium concentration [7].

Figure 2:  Competing outcomes for continuous flow LVADS (82% survival at 1 year, intention to treat).

Transplantation eligibility is always considered with regard to risk factors, especially, pulmonary hypertension (Figure 2). Right heart catheterization must be performed in all potential candidates for heart transplantation in order to quantify pulmonary vascular resistance [7]. Right heart failure is a substantial cause of mortality. Right ventricular failure is likely when post implant pulmonary artery pressures exceed 50 mmHg. Patients with chronic heart failure may develop pulmonary hypertension due to elevated left ventricular end diastolic pressure with elevated left atrial and pulmonary venous pressures. This is a reactive form of pulmonary hypertension and may fall when the cardiac output is increased with inotropes or unloaded with nitrate infusions [7]. The transpulmonary gradient is calculated by subtracting the left atrial filling pressure from the mean pulmonary artery pressure. A fixed transpulmonary gradient in excess of 14 mmHg is associated with greatly elevated risk, and thus this cut off is used in the UK [8]. In such patients a destination therapy strategy may be used with continuous flow LVADS.

Mechanical Circulatory Assist Devices

In recent years, the use of MCS device in treating patients with end-stage heart disease has increased significantly, as bridge to transplantation and as destination therapy for transplant ineligible candidates. This increase is based on the accumulated experience with new second-generation continuous-flow devices which show significant improvements in survival, functional capacity and quality of life [9,10]. On the basis of the Heart Mate II Registry experience (1300 patients), guidelines for the clinical management of patients treated with continuous-flow devices have been published [11]. Risk scoring systems, such as the Seattle Heart Failure Model [12] and the Cumulative Risk Score for 90-Day in-Hospital Mortality [13] and the Destination Therapy Risk Score have been investigated to stratify patients who might benefit from LVAD support [14].

Right ventricle failure is a leading cause of morbidity and death after LVAD implant (incidence of about 35%), and can be very difficult to predict [15,16]. Various means to assess right ventricle function both pre- and postoperatively have been assessed (10). Right ventricular failure risk scores have been created that stratify the risk of right ventricular failure (RVFRS) and death after LVAD implantation (Figure 3). One such RVFRS found independent predictors of right ventricular failure to include vasopressor requirement, aspartate aminotransferase >80 IU/L, bilirubin >2.0mg/dL and creatinine >2.3mg/dL [15]. Another study developed a score to predict RVAD need after LVAD placement, which included factors of cardiac index, right ventricular stroke work index, severe preoperative right ventricular dysfunction, creatinine, previous cardiac surgery and systolic blood pressure [16]. More recently the presence of severe TR and a tricuspid annulus of >43mm and right ventricular sphericity have been proposed as predictive of occult RV failure and need for biventricular support. The Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) registry, which follows all long-term MCS systems in the United States, has defined patient profiles that can help identify risks associated with the timing of implant [17]. In the future, the INTERMACS patient profile would be a useful tool to improve management and outcomes of patients who need VAD implant and unify criteria for future clinical trials and devices (Figure 4). As more LVAD patients are listed for heart transplant, a competition has occurred for organs between stable LVAD supported registrants and less stable registrants listed UNOS status 1A or 1B (the highest categories and most at risk if not urgently transplanted). A recent study found that stable LVAD patients had significantly less 30-day risk of events compared to other status 1A patients concluding that allowance of 30 days of elective status 1A time should not be allocated to stable registrants with implanted LVADs [18]. As VAD technology improves, further revisions to the allocation system will need to be recommended.

Figure 3:  Heartmate 3, the latest centrifugal blood pump in comparison to Heartmate II an axial flow pump. Superior event free survival is seen with HM 3.

Figure 4:  Heart-mate 3 vs Heartmate II comparison of event free survival.

INTERMACS Profile and Description and Timescale to MCS

a) “Crashing and burning”—critical cardiogenic shock. Within hours b) “Progressive decline”—inotrope dependence with continuing deterioration. Within a few days c) “Stable but inotrope dependent”—describes clinical stability on mild-to-moderate doses of intravenous inotropes (patients stable on temporary circulatory support without inotropes are within this profile). Within a few weeks d) “Recurrent advanced heart failure”—“recurrent” rather than “refractory” decompensation. Within weeks to months e) “Exertion intolerant”—describes patients who are comfortable at rest but are exercise intolerant. Variable f) “Exertion limited”—describes a patient who is able to do some mild activity but fatigue results within a few minutes of any meaningful physical exertion. Variable g) “Advanced NYHA III”—describes patients who are clinically stable with a reasonable level of comfortable activity, despite history of previous decompensation that is not recent. Not a candidate for MCS

INTERMACS = Interagency Registry for Mechanically Assisted

Circulatory Support; MCS = mechanical circulatory support;

NYHA = New York Heart Association.

Figure 5:  Durability of HM 3 vs HM II, freedom from pump replacement due to pump thrombosis or haemolysis.

Temporary MCS are available that can be implanted quickly and simply to normalise cardiac output in patients with severe acutely decompensated heart failure. The CentriMag [19], Tandem Heart [20], Impella [21] and Circulite [22]. Clinical trials suggest that treatment of temporary VADs does not necessarily correlate with better survival, but merely comprise a component of treatment leading to recovery, upgrade to fully implantable systems as a bridge to transplant or destination therapy, or transplantation [23,24]. Device miniaturisation, without externalized drive-lines connecting the device to a console and longer endurance will be the future trend of mechanical design for long term support. Blood pumps with magnetically levitated rotors has shown satisfactory 1-year survival [25]. The smaller size and weight of the continuousflow devices has allowed an extension of the new VADs into smaller patients. Fully wireless resonant coupling power sources are currently undergoing evaluation, which if successful will greatly reduce the incidence of drive line infections (Figure 5), which is the weakest point of the technology of current fully implantable systems. There is some evidence that fully implantable systems will be available in the near future to greatly improve the quality of life and to reduce the frequency of severe infections with continuous flow LVADS.

Many recent studies have focused on the reversed molecular and cellular alterations, such as improved β-adrenergic responses and decreased calcium-regulating gene expression (Figure 6), in patients using LVAD as a bridge to recovery therapy [26]. Functional recovery has been observed in a subset of heart failure patients [26,27]. Recently, a clinical trial using clenbuterol (β-2 agonist and anabolic agent) and LVAD in refractory non-ischemic heart failure patients, reported recovery of heart function in 60% of patients (n=20) with non-ischemic cardiomyopathy that allows the pump to be explanted (Harefield Recovery Protocol Study for Patients with Refractory Chronic Heart Failure, HARPS) [28]. LVAD therapy is associated with decreased collagen turnover and crosslinking and increased tissue angiotensin II. LVAD combined with angiotensinconverting enzyme inhibition results in decreased tissue angiotensin II and collagen cross-linking, normalizes left ventricular end-diastolic pressure volume relationships and is associated with modestly higher rates of bridge to recovery [29]. Other adjunctive treatments including other medications, cell or gene therapy with over expression of SERCA2a might in conjunction with VAD support provide a meaningful alternative therapy in patients with severe heart disease [30].

Figure 6.  

Conclusion

Heart transplantation is associated with excellent long-term outcomes and is the gold standard solution for intractable end stage heart failure in eligible patients. What limits its impact, overall, is the limited availability of donor organs. The development of ventricular assist devices has mitigated against this, to some extent. Subsequent device iterations with further miniaturisation and continuous flow have resulted in effective bridge to transplant solutions. The presence of an externalized drive line exposes the VAD recipient to infections, however, which may precipitate urgent listing for heart transplant in the bridge to transplant candidate and may limit the life span of the destination therapy candidate. Fully implantable driveline free systems will definitely enhance the utility of these systems in these settings. As our knowledge of molecular medicine increases, manipulation of key proteins implicated in the pathophysiology of heart failure such as SERCA2a may allow some recovery of the myocardium in patients with heart failure to the extent that transplantation may be deferred or the LVAD explanted [31-35].

https://lupinepublishers.com/cardiology-journal/pdf/ACR.MS.ID.000125.pdf

For more Cardiovascular Research go through the below link

https://lupinepublishers.com/cardiology-journal/index.php

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[dnblines]

LIQUID GIRAFFE LIVE W MC DCD on THE BPM DNB JUNGLE FREQ PRE-CINCO

160kbps, 44mins

LIQUID GIRAFFE LIVE W MC DCD on THE BPM DNB JUNGLE FREQ PRE-CINCO was originally published on Drum and Basslines

[me-radio]

Good morning ME-RADIO FAMILY & FRIENDS, Start Booking one of the Best Dj/Dancer/Mc/Radio Host for your next Holday Party, Baby shower, Comic-Con, Festival etc. Plus we can have you event Live on our Radio Broadcasting Station me-radio.com SHARE/SPREAD/SUPPORT GREAT MUSIC & INTERVIEWS "RADIO FOR ME, RADIO FOR YOU" #NOWPLAYING #MUSICISMYLIFE #MERADIO1 #THEPHENOMENALDJ #FAMLEEFIRST #INSTAFOLLOWERS #DCD #DIGITALCRATEDIGGERS #ncredible_audio #instashare #instalikes https://www.instagram.com/p/BrXuOO8AYuJ/?utm_source=ig_tumblr_share&igshid=xj4688z8yfu0

[magicsoundblog]

Denon PMA-1600NE - Black Denon PMA-1600NE - Black - State-of-the-art Denon Solutions Uscita 2 x 140 W (4 ohm) - Potenza sufficiente anche per grandi ambienti Stadio di amplificazione Advanced Ultra High Current (UHC)-MOS Single Push-Pull con diodi a barriera Schottky - Ampia larghezza di banda, da bassi profondi ad alti dettagliati DAC Master Clock Design - Riproduzione audio Jitter-free Ingresso posteriore USB-B - Riproduzione Audio alta risoluzione fino a 384 kHz / 32 bit e DSD 11.2 MHz Isolatore digitale per eliminare il rumore di computer ad alta frequenza su USB-B - Godetevi le vostre sorgenti preferite senza disturbi indesiderati Display fluorescente per l'indicazione della sorgente e della frequenza di campionamento- Informazioni più importanti sempre in vista Modalità analogica AMP per la pura riproduzione audio spegnendo il circuito audio digitale e la visualizzazione - Riproduzione Pure analogue audio Advanced AL32 Processing Plus - Registrazioni Digitali fedeli al suono originale Costruzione Direct Mechanical Ground Construction - Minimizzazione delle vibrazioni indesiderate Chassis con 6 blocchi indipendenti - Eliminaione disturbi tra i circuiti Trasformatore principale con alimentazioni separate per i circuiti analogico e digitale - Preserva l'integrità del segnale audio 2 ingressi digitali ottici e 1 ingresso digitale coassiale; Equalizzatore Phono MM & MC ad alte prestazioni - Pronto per musica da tutte le sorgenti Disponibile in Premium Silver e Nero - Abbinamento perfetto con il Super Audio CD Player DCD-1600NE https://www.magicsound.it/?p=12107

[canchinhamthanh]

Ampli Denon PMA-1600NE: Chiều Lòng Cả Người Chơi Nhạc Số Lẫn Analogue

Ampli Denon PMA-1600NE có công suất 140 watt/kênh 4ohms được trang bị hàng loạt công nghệ chống rung nhiễu, kèm theo bộ xử lý tín hiệu số qua công USB tới chuẩn 11.2MHz DSD và ngõ xử lý tín hiệu phono MM/MC.

Ampli Denon luôn được tiếng là dễ “xài” trong các hệ thống hi-fi dành cho những người mới làm quen với audio với khả năng phối ghép tương đối tốt. Tuy nhiên, với sản phẩm PMA-1600NE, dường như các kỹ sư của Denon có tham vọng xa hơn thế.

Chiếc ampli tích hợp này không chỉ có công suất khá lớn (140 watt/kênh 4ohms) mà còn sở hữu hàng loạt chuẩn kết nối cho phép người dùng tận dụng tối đa hệ thống phần mềm của mình, từ những chiếc đĩa nhựa cổ điển cho tới các file nhạc số chuẩn PCM hay DSD. 

Có thể nói đây là thiết bị all-in-one (tất cả trong một), tiện ích, đẹp mắt, đáng lưu tâm đối với những người muốn làm quen với âm thanh hi-fi. Điểm đặc biệt, tuy có giá bán chỉ 31 triệu đồng/sản phẩm, nhưng thiết bị được chế tạo hoàn toàn tại Nhật Bản. 

Dưới đây là một số điểm nhất trong thiết kế và tính năng của ampli tích hợp Denon PMA-1600NE.

Mạch đẩy kéo đơn MOS sử dụng dòng siêu cao

Ampli được trang bị công nghệ khuếch đại MOS tiên tiến UHC (Ultra High Curren – Dòng siêu cao) cho phép tận dụng tối đa dòng khuếch đại để duy trì hoạt động kiểm soát loa cũng như chất lượng âm thanh.

Khuếch đại tiên tiến UHC-MOS khai thác tối đa hiệu suất của biến áp nguồn với các transitor lưỡng cực để có được âm thanh tốt nhất từ sò MOS-FET. Mạch UHC-MOS còn có khả năng hạn chế độ sai lệch giữa tầng khuếch đại và cân bằng lại dòng cao nhằm tái hiện được âm nhạc với độ chi tiết đáng kể.

Chống rung/nhiễu động tối đa

Ampli được chia thành 6 khoang độc lập chứa các mạch xử lý khác nhau gồm bộ điều khiển phono và hệ thống tín hiệu đầu vào, mạch điều khiển âm lượng, mạch USB-DAC, mạch khuếch đại, phần nguồn điện và phần điều khiển.

Bộ khung máy được làm từ thép dày 1.0mm bảo vệ các mạch tín hiệu khỏi rung động từ bên ngoài và can nhiễu giữa các mạch điện bên trong. Phần cấp nguồn được bố trí ở giữa, cánh tản nhiệt được lắp đều hai bên máy. Cấu trúc này tạo nên độ cân bằng cao cho máy, giảm thiểu rung lắc gây ảnh hưởng xấu đến âm thanh.

Thuật toán xử lý AL32

Để xử lý nguồn tín hiệu digital, PMA-1600NE được trang bị thuật toán xử lý tiên tiến AL32. Đây là công nghệ tái tạo sóng analogue mới nhất của Denon với khả năng tận dụng tối đa các dữ liệu được nội suy, đồng thời hỗ trợ tốt cho việc tái tạo nguồn nhạc chất lượng cao PCM 384kHz/32bit.

Thông qua việc hoàn trả một cách thận trọng đối với những tín hiệu bị suy hao trong quá trình số hoá tín hiệu, âm thanh tái tạo có độ chi tiết cao, không can nhiễu, chính xác và giàu năng lượng ở dải tần thấp.

Cách ly phần xử lý tín hiệu digital và analog

PMA-1600NE được trang bị máy cách ly digital tốc độ cao nhằm giảm thiểu những tác động tiêu cực đến âm thanh gây nên bởi nhiễu cao tần giữa kết nối với máy tính thông qua cổng USB cũng như các ngõ vào digital khác.

Với chế độ này, dữ liệu được truyền dẫn chính xác theo thuật toán được mã hóa trong một IC gắn trên máy. Dữ liệu vào và ra của quá trình này được cách ly bằng điện. Thông qua việc cách ly mạch xử lý tín hiệu số với bộ chuyển đổi tín hiệu D/A, nhiễu cao tần đã bị loại bỏ khỏi mạch analogue.

PMA-1600NE cũng bố trí thêm một vòng thứ cấp trong biến áp nguồn cho mạch digital nhằm triệt nhiễu từ nguồn cấp điện. Trong suốt quá trình xử lý tín hiệu analogue, máy cho phép người dùng sử dụng chức năng Analog Mode. Chức năng này tắt toàn bộ các mạch cấp nguồn xử lý tín hiệu digital để loại bỏ nhi���u cao tần tới bộ phận khuếch đại analogue.

Analog Mode cũng ngắt luôn cả mạch hiển thị, cho phép PMA-1600NE hoạt động như một tăng âm analogue thuần túy. Với chế độ này thì các ngõ vào cho tín hiệu số đều ngừng hoạt động.

USB-DAC với nhạc chuẩn DSD 11.2MHz và PCM 384kHz/32bit

Với PMA-1600NE, người dùng có thể khai thác được kho nhạc số của mình thông qua cổng USB với một bộ DAC gắn trong cho phép xử lý âm thanh chuẩn DSD 11.2MHz và PCM 384kHz/32bit.

Giao thức truyền dẫn và xử lý tín hiệu DSD của máy hỗ trợ cả ASIO (native) lẫn DSD Audio, và PCM. Đặc biệt, tín hiệu dẫn truyền không đồng bộ được máy tạo xung chủ của PMA-1600NE xử lý chứ không cho phép bộ đếm của máy tính can thiệp nên hệ thống không có nhiễu jitter.

Bộ chuyển đổi tín hiệu D/A trong ampli PMA-1600NE cũng chính là chi tiết được trang bị trên đầu đọc DCD-1600NE, cho phép tái tạo âm thanh sạch sẽ, giàu chi tiết.

  Mạch phono MM/MC

Không nhiều ampli hiện tại được trang bị cùng lúc cả mạch xử lý tín hiệu phono MM lẫn MC như PMA-1600NE. Để lựa chọn tín hiệu MM hoặc MC nhằm chơi với đầu kim cùng loại, thay vì nút nhấn như các thế hệ trước, PMA-1600NE sử dụng nút gạt. Thiết kế tưởng đơn giản này hóa ra lại có thể giản lược được bo mạch khiến vòng lặp tín hiệu nhỏ hơn, cho phép khuếch đại tín hiệu analogue với độ trung thực cao hơn.

Điểm nhấn của PMA-1600NE

Công suất 140 watt/kênh 4Ohm có thể chơi nhạc trong không gian lớn.

Sử dụng mạch khuếch đại công suất đẩy kéo đơn (UHC)-MOS dòng siêu cao với dioes chặn của Schottky tái tạo dải tần rộng từ tiếng trầm sâu tới âm cao chi tiết.

Bộ chuyển đổi tín hiệu DAC được trang bị máy tạo xung chủ không nhiễu jitter.

Mạch xử lý tín hiệu USB và các ngõ nhận tín hiệu digital được bố trí độc lập nhằm hạn chế nhiễu cao tần từ máy tính.

Có chế độ Analog AMP – ngắt toàn bộ mạch ditigal cũng như các trình hiển thị khiến tín hiệu analog được tái tạo thuần khiết.

Bộ khung máy được xây dựng theo cấu trúc cơ khí có độ bám trụ cao, giảm thiểu rung lắc không mong muốn.

Máy được chia thành 6 khối độc lập, hạn chế tối đa can nhiễu giữa các mạch tín hiệu.

Biến áp nguồn với hai khối cấp nguồn riêng rẽ cho mạch analog và mạch digital bảo toàn quá trình xử lý tín hiệu trung thực.

Máy sở hữu hàng loạt kết nối linh hoạt với 2 ngõ vào quang học và một ngõ vào đồng trục cho tín hiệu số; có ngõ tín hiệu MM/MC để kết nối với đầu đọc đĩa nhựa.

Nhà phân phối: ANH DUY AUDIO

Một số hình ảnh chi tiết của ampli Denon PMA-1600NE:

      Nguồn: https://stereo.vn

Bài viết Ampli Denon PMA-1600NE: Chiều Lòng Cả Người Chơi Nhạc Số Lẫn Analogue có nguồn tại Thiết B��� Karaoke, Xem Phim, Nghe Nhạc Số 1 Tại TPHCM.

[vidiashopnet]

Ampli Denon PMA-1600NE: Chiều Lòng Cả Người Chơi Nhạc Số Lẫn Analogue

Ampli Denon PMA-1600NE có công suất 140 watt/kênh 4ohms được trang bị hàng loạt công nghệ chống rung nhiễu, kèm theo bộ xử lý tín hiệu số qua công USB tới chuẩn 11.2MHz DSD và ngõ xử lý tín hiệu phono MM/MC.

Ampli Denon luôn được tiếng là dễ “xài” trong các hệ thống hi-fi dành cho những người mới làm quen với audio với khả năng phối ghép tương đối tốt. Tuy nhiên, với sản phẩm PMA-1600NE, dường như các kỹ sư của Denon có tham vọng xa hơn thế.

Chiếc ampli tích hợp này không chỉ có công suất khá lớn (140 watt/kênh 4ohms) mà còn sở hữu hàng loạt chuẩn kết nối cho phép người dùng tận dụng tối đa hệ thống phần mềm của mình, từ những chiếc đĩa nhựa cổ điển cho tới các file nhạc số chuẩn PCM hay DSD. 

Có thể nói đây là thiết bị all-in-one (tất cả trong một), tiện ích, đẹp mắt, đáng lưu tâm đối với những người muốn làm quen với âm thanh hi-fi. Điểm đặc biệt, tuy có giá bán chỉ 31 triệu đồng/sản phẩm, nhưng thiết bị được chế tạo hoàn toàn tại Nhật Bản. 

Dưới đây là một số điểm nhất trong thiết kế và tính năng của ampli tích hợp Denon PMA-1600NE.

Mạch đẩy kéo đơn MOS sử dụng dòng siêu cao

Ampli được trang bị công nghệ khuếch đại MOS tiên tiến UHC (Ultra High Curren – Dòng siêu cao) cho phép tận dụng tối đa dòng khuếch đại để duy trì hoạt động kiểm soát loa cũng như chất lượng âm thanh.

Khuếch đại tiên tiến UHC-MOS khai thác tối đa hiệu suất của biến áp nguồn với các transitor lưỡng cực để có được âm thanh tốt nhất từ sò MOS-FET. Mạch UHC-MOS còn có khả năng hạn chế độ sai lệch giữa tầng khuếch đại và cân bằng lại dòng cao nhằm tái hiện được âm nhạc với độ chi tiết đáng kể.

Chống rung/nhiễu động tối đa

Ampli được chia thành 6 khoang độc lập chứa các mạch xử lý khác nhau gồm bộ điều khiển phono và hệ thống tín hiệu đầu vào, mạch điều khiển âm lượng, mạch USB-DAC, mạch khuếch đại, phần nguồn điện và phần điều khiển.

Bộ khung máy được làm từ thép dày 1.0mm bảo vệ các mạch tín hiệu khỏi rung động từ bên ngoài và can nhiễu giữa các mạch điện bên trong. Phần cấp nguồn được bố trí ở giữa, cánh tản nhiệt được lắp đều hai bên máy. Cấu trúc này tạo nên độ cân bằng cao cho máy, giảm thiểu rung lắc gây ảnh hưởng xấu đến âm thanh.

Thuật toán xử lý AL32

Để xử lý nguồn tín hiệu digital, PMA-1600NE được trang bị thuật toán xử lý tiên tiến AL32. Đây là công nghệ tái tạo sóng analogue mới nhất của Denon với khả năng tận dụng tối đa các dữ liệu được nội suy, đồng thời hỗ trợ tốt cho việc tái tạo nguồn nhạc chất lượng cao PCM 384kHz/32bit.

Thông qua việc hoàn trả một cách thận trọng đối với những tín hiệu bị suy hao trong quá trình số hoá tín hiệu, âm thanh tái tạo có độ chi tiết cao, không can nhiễu, chính xác và giàu năng lượng ở dải tần thấp.

Cách ly phần xử lý tín hiệu digital và analog

PMA-1600NE được trang bị máy cách ly digital tốc độ cao nhằm giảm thiểu những tác động tiêu cực đến âm thanh gây nên bởi nhiễu cao tần giữa kết nối với máy tính thông qua cổng USB cũng như các ngõ vào digital khác.

Với chế độ này, dữ liệu được truyền dẫn chính xác theo thuật toán được mã hóa trong một IC gắn trên máy. Dữ liệu vào và ra của quá trình này được cách ly bằng điện. Thông qua việc cách ly mạch xử lý tín hiệu số với bộ chuyển đổi tín hiệu D/A, nhiễu cao tần đã bị loại bỏ khỏi mạch analogue.

PMA-1600NE cũng bố trí thêm một vòng thứ cấp trong biến áp nguồn cho mạch digital nhằm triệt nhiễu từ nguồn cấp điện. Trong suốt quá trình xử lý tín hiệu analogue, máy cho phép người dùng sử dụng chức năng Analog Mode. Chức năng này tắt toàn bộ các mạch cấp nguồn xử lý tín hiệu digital để loại bỏ nhiễu cao tần tới bộ phận khuếch đại analogue.

Analog Mode cũng ngắt luôn cả mạch hiển thị, cho phép PMA-1600NE hoạt động như một tăng âm analogue thuần túy. Với chế độ này thì các ngõ vào cho tín hiệu số đều ngừng hoạt động.

USB-DAC với nhạc chuẩn DSD 11.2MHz và PCM 384kHz/32bit

Với PMA-1600NE, người dùng có thể khai thác được kho nhạc số của mình thông qua cổng USB với một bộ DAC gắn trong cho phép xử lý âm thanh chuẩn DSD 11.2MHz và PCM 384kHz/32bit.

Giao thức truyền dẫn và xử lý tín hiệu DSD của máy hỗ trợ cả ASIO (native) lẫn DSD Audio, và PCM. Đặc biệt, tín hiệu dẫn truyền không đồng bộ được máy tạo xung chủ của PMA-1600NE xử lý chứ không cho phép bộ đếm của máy tính can thiệp nên hệ thống không có nhiễu jitter.

Bộ chuyển đổi tín hiệu D/A trong ampli PMA-1600NE cũng chính là chi tiết được trang bị trên đầu đọc DCD-1600NE, cho phép tái tạo âm thanh sạch sẽ, giàu chi tiết.

  Mạch phono MM/MC

Không nhiều ampli hiện tại được trang bị cùng lúc cả mạch xử lý tín hiệu phono MM lẫn MC như PMA-1600NE. Để lựa chọn tín hiệu MM hoặc MC nhằm chơi với đầu kim cùng loại, thay vì nút nhấn như các thế hệ trước, PMA-1600NE sử dụng nút gạt. Thiết kế tưởng đơn giản này hóa ra lại có thể giản lược được bo mạch khiến vòng lặp tín hiệu nhỏ hơn, cho phép khuếch đại tín hiệu analogue với độ trung thực cao hơn.

Điểm nhấn của PMA-1600NE

Công suất 140 watt/kênh 4Ohm có thể chơi nhạc trong không gian lớn.

Sử dụng mạch khuếch đại công suất đẩy kéo đơn (UHC)-MOS dòng siêu cao với dioes chặn của Schottky tái tạo dải tần rộng từ tiếng trầm sâu tới âm cao chi tiết.

Bộ chuyển đổi tín hiệu DAC được trang bị máy tạo xung chủ không nhiễu jitter.

Mạch xử lý tín hiệu USB và các ngõ nhận tín hiệu digital được bố trí độc lập nhằm hạn chế nhiễu cao tần từ máy tính.

Có chế độ Analog AMP – ngắt toàn bộ mạch ditigal cũng như các trình hiển thị khiến tín hiệu analog được tái tạo thuần khiết.

Bộ khung máy được xây dựng theo cấu trúc cơ khí có độ bám trụ cao, giảm thiểu rung lắc không mong muốn.

Máy được chia thành 6 khối độc lập, hạn chế tối đa can nhiễu giữa các mạch tín hiệu.

Biến áp nguồn với hai khối cấp nguồn riêng rẽ cho mạch analog và mạch digital bảo toàn quá trình xử lý tín hiệu trung thực.

Máy sở hữu hàng loạt kết nối linh hoạt với 2 ngõ vào quang học và một ngõ vào đồng trục cho tín hiệu số; có ngõ tín hiệu MM/MC để kết nối với đầu đọc đĩa nhựa.

Nhà phân phối: ANH DUY AUDIO

Một số hình ảnh chi tiết của ampli Denon PMA-1600NE:

      Nguồn: https://stereo.vn

Bài viết Ampli Denon PMA-1600NE: Chiều Lòng Cả Người Chơi Nhạc Số Lẫn Analogue có nguồn tại Thiết Bị Karaoke, Xem Phim, Nghe Nhạc Số 1 Tại TPHCM.

[tellodona]

masterlist !

obey me

the brothers

obey me headcanons (just because)

the brothers + side characters with an mc whose first language isn't english

the brothers with an mc who has heat sensory issues

the brothers seeing mc use sfx makeup

the brothers with an mc who has dyspraxia / dcd

the brothers when mc sits in a bone-cracking (for them) position

the brothers with an mc who has stretch marks

lucifer

The Shepherd and His Lamb

side characters

obey me headcanons (just because)

the brothers + side characters with an mc whose first language isn't english

the angels with an obsessive mc who has borderline personality disorder

simeon

birthday special 2024: simeon headcanons

birthday special 2024: simeon's views on the cast

solomon

if gojo satoru and solomon ever met (a short thought)

luke

mc as luke's parental figure headcanons

thirteen

thirteen fluff headcanons

jujutsu kaisen

gojo satoru

if gojo satoru and solomon ever met (a short thought)