#hypogonads

[isobug]

Hyperhormonal ( Hypergonadism ) and Hypohormonal ( Hypogonadism ) general flags and symbols

These are heavily based off of the meanings and colors of my Hyperandrogenism / Hyperestrogenism and Hypoandrogenism / Hypoestrogenism flags. Though the white stripe on these is intended to represent those who have other Hypo- / Hyper- variations as well ( or a mix / combination of variations. )

The symbols are totally copyright free! Here they are isolated:

These are free to be use anywhere by anyone. I just ask that perisex people please be respectful.

Taglist - @radiomogai, @revenant-coining, @interarchive

[intersex-support]

Does hypogonadism count as interex? All I see is people talking about feminization and masculization when I got neither, so I don't really feel included.

Unlike typical intersex people, I was never given hrt, because they said I was "too young to have hormone issues", so I don't know if there's a point calling myself intersex for social/relateblity reasons.

I remember seeing a post about someone who got hypogonadism from cancer treatment, and everyone saying they don't count as intersex in the comments. I was just born like this I guess, nothing to do with any treatments, but I felt bad reading it.

It seems like no one what I have.

Sorry for being venty/negative, I don't know any other blogs.

Hi anon!

I can definitely understand how isolating that would feel to not see any representation of people who have your variation, or feel like most of the time the things that people talk about as "intersex issues" don't feel relatable to you. You deserve to feel supported and welcomed in the community, and you don't have to apologize for venting--there's always room for that here.

There are definitely a lot of intersex variations that are related to hypogonadism (Kallman Syndrome, Turner Syndrome, Klinefelter Syndrome, etc). InterACT lists hypogonadism as something that can often be an intersex variation on their glossary:

"A person with hypogonadism produces lower-than-typical levels of hormones like testosterone and estrogen, or sometimes none at all. This can affect how a person’s secondary sex characteristics develop, and can also affect their fertility. Hypogonadism can be a result of a difference in how someone’s brain signals their gonads to produce (or not produce) hormones, or it can be a feature of their gonads directly. Hypogonadism is not always caused by an intersex variation, but can be related to Klinefelter Syndrome, Turner Syndrome, or several other variations."

So yes, hypogonadism definitely can "count" as intersex and you are welcome in the intersex community. In fact, I met multiple intersex people with hypogonadism at the intersex conference I went to last summer, so you definitely are not the only one. And I think that there is a lot of room for solidarity and resource sharing between people whose hypogonadism is associated with intersex variation and people whose hypogonadism is caused by side effects of treatment, regardless of whether people personally identify with the intersex label or not.

Anyway, all this is to say that yes, hypogonadism is considered intersex and there are resources and support groups out there if you are interested in exploring.

Best wishes, anon 💜💜💜

[ipso-faculty]

I just wanted to ask for clarification on the redefinition of the term mesosex, am I correct in assuming that it no longer describes me? I'm someone who had started identifying with the term due to being part of the "group 8" that you described in your original discussion as being the intended audience:

Not seen as intersex by intersex people: PMDD, endometriosis, and other reproductive disorders, who may relate to the intersex experience anyway. Reading asks that @queercripintersex got from people in this category was what gave me the seed of the idea for mesosex.

More specifically, I have endometriosis which seems to be related to low progesterone, and now that I'm on progesterone HRT to treat my endo I'm having the weird experience of undergoing hormonal feminization (breast growth, fat redistribution, etc) for the first time at the age of 25. So I'm technically perisex, but it feels kinda weird calling myself that when I'm an afab person on feminizing HRT that's making me go through the same physical changes my transfem friends are going through 😅 I also feel that I identify with some of the experiences I've heard from intersex people about social ostracization due to not fitting in with society's ideas about sex and gender. I was treated differently as a teenager by some people due to not "looking like" a girl for one, and personally I also feel alienated when people (primarily transphobes tbh) talk about how a universal and important experience of growing up as a girl is that after you go through puberty strangers start sexualizing you, because I... never experienced that. My body just didn't develop that way (not that I'm complaining, but you know)

I just wanted to make sure like... should I stop using the term? I thought I had found something that described my experiences, but if I no longer fit the definition then I don't want to be like disrespectful or anything

Hi! Thank you for the ask! 🩵

So my first reaction on glancing at your ask was "maybe there should be a term for the group 8 people". 🤔

But then I sat down and properly read your ask, and... I'm not actually sure you're group 8? 🤔 My personal conviction is that an AFAB with chronically low progesterone to an extent that it would have had noticeable effects on pubertal development & social development is intersex in the same ways that somebody with chronically low estrogen is considered intersex.

Hypogonadism is in InterAct's list of variations, and I don't see how hypoprogesteronism wouldn't be be a kind of hypogonadism. 🧐 Wikipedia includes low progesterone in their page on hypogonadism. Here's how InterAct defines it:

Similarly, MOGAI wiki defines hypogonadism as intersex and explicitly mentions low progesterone. But I can see somebody dismissing MOGAI wiki as being on the more radical side of things.

So for the most conservative/intermedicalist takes within the pan-intersex community I look to what ISNA has on their website. And they list hypogonadotrophic hypogonadism as an intersex variation - i.e. hypogonadism wherein you don't have a complete puberty, which it sounds like could be the case for you?

So to me I think you're actually in group 5? 😅 So the redefinition of mesosex is still scoped in a way that (as far as I'm concerned) would still include you. 🤠

But if I've misunderstood your case and you don't think hypogonadism applies, perhaps there is a need to create a word for what I had dubbed group 8 (people with reproductive disorders that identify with intersex people but whom are not generally accepted as intersex by the intersex community). Maybe juxtasex could be repurposed for this since it never really got taken up as a term for non-intersex? Or a new word entirely? 🤔

Though honestly I don't know how big the demand is. NGL: every time I've interacted with somebody with PMDD/endometriosis who identifies with intersex people, once they start explaining why, I get the distinct impression they have an intersex variation that has been underexplored. 🤷 I kinda suspect that the PMDD/endometriosis people who aren't sure if they're intersex would be served by the already existing term "extersex". 👀

IDK, let me know what you think! Happy to think about coining new terms. 🤓

[cosmotheo]

Please Help Me Get Testosterone

Hi, I'm in pretty dire need of some help. I'm a 26 year old cis male, and I have had critically low Testosterone levels for years.

Since 2020, when I started dealing with my medical issues on my own, my doctors have told me I have very, VERY low testosterone. My levels range between 80 - 90 ngdl, which is about 1/4 of the bottom of average range. They aren't sure why, and all of the tests we've done have come back inconclusive. I don't have an adenoma, I'm not sterile, so I don't know what's going on. They want me to travel weekly to a town an hour away to get my shots, since it's the closest place that will take my insurance. Thing is, I don't have a car, and public transportation doesn't get me there early enough. My insurance won't cover the at-home injections, and without insurance it's hundreds of dollars, much more than I can afford.

It has been pretty bad since 2020, but within the last few months it's gotten so much worse. Several times a week I'll get debilitating muscle pains out of nowhere. I am constantly fatigued and out of energy, I put on weight like crazy, and sometimes even standing for too long hurts my whole body. I'm constantly weak and in pain, and I don't know how much longer I can do this.

Please, if you know of anything that can be done to help my situation out, let me know. My doctor has been incredibly ineffective in fighting for me, and I don't have the resources to do this on my own. Thank you in advance for any help you're able to provide.

[mcatmemoranda]

Low testosterone

FSH and LH tell the testes and ovaries to make sex hormones and gametes. So if you're making a lot of FSH and LH, it's because your brain is trying to tell your sex organs to make what they're supposed to make. If the testes aren't responding to LH, then the pituitary will make more LH, trying to get the testes to go. So if you have low testosterone and high LH, it's primary hypogonadism, meaning the testes are just not making the testosterone. If your testosterone is low and your LH is low, then it's secondary hypogonadism because your brain isn't making enough LH to stimulate the testes to make testosterone.

From UpToDate:

Definition – Hypogonadism in a male refers to a decrease in either or both of the two major functions of the testes: sperm production and testosterone production. These abnormalities may result from disease of the testes (primary hypogonadism) or disease of the pituitary or hypothalamus (secondary hypogonadism).

●Signs and symptoms

•Failure to undergo or complete puberty indicates deficient testosterone secretion.

•Symptoms that could indicate hypogonadism in a man are decreases in energy, libido, muscle mass, and body hair, as well as hot flashes, gynecomastia, and infertility.

●Candidates for testing – We suggest case detection by measuring serum testosterone when hypogonadism is suspected, such as in those with sexual symptoms, osteoporosis-associated fractures, human immunodeficiency virus (HIV)-associated weight loss, those taking sustained-release opioids or high-dose glucocorticoids for prolonged periods, and those who are incompletely virilized or have small testes on examination.

Men with acute or subacute illness should not be assessed for hypogonadism, as they will have a transient functional secondary hypogonadism.

●Evaluation

•Serum total testosterone – To make the diagnosis of hypogonadism, we suggest measuring a morning serum total testosterone concentration between 8 and 10 AM on at least two days.

•Serum free testosterone – Measurement of the serum free testosterone concentration is worthwhile only when it is suspected that an abnormality in testosterone binding to sex hormone-binding globulin (SHBG) coexists with hypogonadism. The two most common situations of abnormal testosterone binding are obesity, which decreases SHBG concentrations, and aging, which increases SHBG.

•LH and FSH – If the total testosterone is subnormal, it should be repeated between 8 and 10 AM, and serum luteinizing hormone (LH) and follicle stimulating (FSH) concentrations should be measured to distinguish primary from secondary hypogonadism.

•Semen analysis – A semen analysis is also part of the evaluation of hypogonadism if the patient is pursuing fertility or has been diagnosed with infertility. If subnormal, a serum FSH concentration is measured to distinguish primary from secondary hypogonadism.

●Interpretation of results

•Primary hypogonadism – The patient has primary hypogonadism if the serum testosterone concentration and/or the sperm count are consistently below normal and the serum LH and/or FSH concentrations are above normal.

•Secondary hypogonadism – The patient has secondary hypogonadism if the serum testosterone concentration and/or the sperm count are consistently subnormal and the serum LH and/or FSH concentrations are normal or reduced.

[biology-geology-beaches-india]

The Research Diaries of S. Sunkavally, page 328.

[texanshealthandwellnesscenter]

Low testosterone: Symptoms, causes, and treatment

Learn the symptoms, causes, and treatments for low testosterone. Regain vitality with expert care at Texans Health and Wellness Center.

[suntreeendocrinology]

Osteoporosis Treatment 

Hypogonadism treatment aims to restore normal hormone levels, addressing symptoms like low libido and fatigue. Osteoporosis treatment focuses on strengthening bones and preventing fractures through medications, lifestyle changes, and supplements, improving overall bone health and quality of life.

[coachcatasha]

Low Testosterone

Low testosterone can have devastating effects on the body and the psyche. Testosterone plays a part in many functions of the body. Beyond separating the sexes during pregnancy, it also aids in managing the sex drive, muscle size, and bone growth. Testosterone is necessary for male and female bodies and is often used to treat symptoms of low libido in women. Hormones decline over time in men as…

[trash-and-trash-accessories]

Yes. That's what we're discussing here.

The tightrope black women are expected to walk is much thinner and higher than their white counterparts. They are expected to maintain a very specific aesthetic. While white women can explore different levels of femininity, black women aren't allowed to explore femininity in the same way. They have to maintain a specific standard and not stray too far in either direction. Especially women of color exploring traditional feminine dress from their own cultural backgrounds like ornate hair wraps, protective braided styles, and other forms of natural hair styles which are considered "unprofessional." Femininity is strictly controlled in black women, there were many laws surrounding black women in the US South regarding what hair styles and clothes they could wear for like a long time, way longer than you would think. Their bodies in feminine styles are hyper-sexualized and commodified more than their white counterparts. An outfit considered appropriate on a white girl would be considered problematic, explicit, unprofessional on a black girl. There's a huge disparity in dress code violations among black girls in schools. Black girls are disproportionately punished for all forms of offenses but especially dress code violations in schools. Starting extremely young.

Their bodies are up for public comment and debate. This happens to women of color, disabled women, and any other bodies considered "outside the norm." As a little person it is constantly happening to me, though to a lesser and different extent than women of color experience.

A black woman doing a hyperfemme style like EGL, Barbiecore, etc will be hypersexualized more than her white peers just by virtue of her blackness. It's part of what's called misogynoir. And failure to maintain a highly specific level of femininity will be punished either through this hypersexualization or through masculinization and transphobia (accusing black women of being men or "practically men" is a form of transphobia that affects a lot of cis women).

This affects all women to a degree but the intersection of blackness really ramps that up.

This same exact mechanism also occurs with indigenous women and causes extreme violence and danger for Native American women specifically in their communities which are often near what are called "Man Camps" which are temporary labor camps of often white laborers building pipelines and mines. And near military bases. These soldiers and laborers only stay in that location for a short while and aren't subject to local or tribal law enforcement so it's very easy for them to get away with the rape and murder of these women who are hypersexualized and offered less protection from society, are seen as less innocent and less needing of protection due to their masculinization.

I recommend White Tears/Brown Scars by Ruby Hamad, which is a very good book on misogynoir that is very readable despite the painful subject matter.

And also Feminism Is For Everybody by bell hooks which a very good piece of intersectional feminist literature.

Someone recommended a book called Hood Feminism by Mikki Kendall but I haven't read it yet.

“reclaiming femininity” SHUT UP SHUT UP you can’t reclaim something that is expected of you and that you are actively punished for not engaging in shut up shut up shut up pink capitalism has won im going to chew glass a

[urosaketnarnoli]

Delve into the intricacies of low testosterone in men, covering its causes, symptoms, diagnosis, and treatment options such as testosterone replacement therapy. Learn about potential risks, prevention strategies, and how it can affect fertility and overall well-being. Consult urologist for personalized guidance on managing this condition and optimizing men's health.

[intersex-support]

Hello!

I saw the previous ask about Hypogonadism and I was wondering if Hypogonadism could occur without being related to other intersex variations (Chromosome related) BUT also not be cause by other outside factors (Like cancer, medicine, diet, stress I guess?)

Like is it possible for the gonads to just have formed wrong? (I'm referring to Primary Hypogonadism in this case)

Hi anon!

So there are a variety of factors that can cause primary hypogonadism outside of some of the intersex variations we've been discussing on the blog today (such as Klinefelters, Turners, Kallmanns), and also aren't things like environmental risk factors, diet, etc. This article mentions that undescended testicles that are never treated could cause primary hypogonadism. This article explains that fragile X syndrome and galactosaemia are two examples of other conditions that can cause hypogonadism. (There are also a lot of factors that can sometimes cause primary hypogonadism such as cancer treatment, hemochromatosis, mumps, and also normal aging, as well as factors that can sometimes cause secondary hypogonadism, such as HIV, Pituitary disorders, certain medications, malnutrition, and stress).

Beyond that, what I think you might be curious about is gonadal dysgenesis, which is essentially a term for when gonads develop atypically or don't develop at all, and is associated with a wide variety of presentations of symptoms, including chromosomal variations, hypogonadism, and various reproductive structures. There are many different intersex variations associated with gonadal dysgenesis, and there are a lot of different ways that gonadal dysgenesis shows up, but it can potentially cause disruptions in ovarian or testicular or ovotestes function. There's some case studies out there exploring different intersex people's experiences with hypogonadism with gonadal dysgenesis.

So basically, long answer is yes, atypical gonadal development is potentially a cause of hypogonadism for some people!

Hope that helped, anon!

[liom-archive]

[PT: Compiling some terms/posts useful for those questioning if intersex Highly relevant terms Subtypes of intersex people More intersex terminology /End PT.]

Compiling some terms/posts useful for people questioning if intersex

Note: If a definition in is in quotes, the source material it is quoted from is linked to by the relevant term.

Highly relevant terms

Extersex - "[A] term for those who do not know whether they are dyadic or intersex. It could be because one feels as though they might be some form of intersex, but are unable to medically confirm it, or cannot confirm what intersex variation it is. It may also be for those who have a variation that may be considered intersex, but are uncertain if they want to identify as intersex." - @themogaidragon

Inter-Questioning - "a term for anyone who is questioning if they’re intersex, for any reason. (Whether it’s due to one’s physical body, familial experiences that imply one is, or possibly simply a mental feeling that one is intersex.)" - @eldorr

Quoisex - "[An] umbrella term for anyone who doesn't quite understand their sex or doesn't want to define their sex." - LGBTQIA+ Wiki Note: I understand this as more general than extersex, and would include people questioning if altersex. See the wiki entry for subtypes (quoigonadal, quoichest, etc)

Altersex - "An umbrella term to describe having or wanting primary or secondary sex traits/characteristics that do not align with the binary sex model that a significant portion of society has adopted. It is primarily used by those who are not intersex and are trans+ and wish to or transition specifically to have a body that does not fit the aforementioned sex model." -@intersex-questions Note: Being altersex does not make somebody intersex. I include it because many people questioning their intersex status realize this is what they're looking for.

Anisohormonal - "Aniso (unequal/uneven) + hormonal (relating to hormones). An individual who has an imbalance of hormones for any number of reasons. Such individuals may or may not also be intersex." - @sproutflags Note: includes non-intersex variations such as diabetes.

Subtypes of intersex people

Note: In my experience most people questioning if they're intersex have a hormonal intersex variation like PCOS, so I'm skewing towards this accordingly.

Dysgonadal - "[having] dysfunctional gonads. This includes agonadal (no gonads) and hypogonadal. Also known as gonadal agenesis/dysgenesis, dyssex and nullogonadal/asexed (null sex or avaginal/aphallia)." - @arco-pluris Note: contrasted with eugonadal - "people with functional gonads (reproductive cells). Includes hypergonadal (hyperfunctional gonads)"

Interhormonal - "Someone who is intersex and anisohormonal and/or feels that being intersex has impacted their identity as anisohormonal in some way and/or that their identity as anisohormonal has impacted their identity as intersex in some way." - @sproutflags

Intermeer - "a term used to describe all intersex variations that are caused by an overproduction of horomones (testosterone, estrogen, or both.)" - LGBTQIA+ Wiki Variations include: AES, FMPP, PCOS. Part of The Autre System for categorizing intersex variations.

Intermindre - "a term used to describe all intersex variations that are caused by a lack of horomones (testosterone, estrogen, or both.)" Note: The wiki lists AIS and EIS as examples although they are not due to a lack of hormones, but rather a lack of sensitivity to them. Part of The Autre System for categorizing intersex variations. See the wiki for more subtypes. Thank you to anon asker who pointed out the AIS/EIS issue.

Mesosex - "[A] person who has an intersex variation, but one which does not conform to perisex (non-intersex) ideas of what intersex is. For example, people who have intersex traits that are considered "mild", or who have variations such as PCOS Hyperandrogenism and Poland Syndrome." - @ipso-faculty

More intersex terminology

Intersex Terminology Masterpost by @intersexfairy

Edits: - 2023-12-13: corrected AIS mischaracterized as lack of hormones, ty to anon for correction - 2023-12-13: added interdynamic - 2023-12-20: added inter-questioning, thank you @fazbears-horror-attraction for sharing it! - 2023-12-21: removed interdynamic. Apparently "secondary sex" means something entirely different in omegaverse. Ty to anon for correction.

[healthcareruhi]

Hypogonadism Drug Market Trend, Size and Growth Opportunity, Forecast till 2030.

Global Hypogonadism Drug Market 

Global Hypogonadism Drug Market was valued at USD 9.15 billion in 2022 and is slated to reach USD 12.7 billion by 2030 at a CAGR of 4.5% from 2022-2030. An insufficient number of hormones are produced by the glands (gonads and ovaries), which results in hypogonadism, a hormonal condition. This hormone is necessary for the operation of several sexual traits. Loss of libido, weakness, infertility, and osteoporosis are all possible symptoms of hypogonadism. The most frequent factor causing hypogonadism is menopause. It often starts around the age of 50 and is normal in all women. 

Market Drivers

Hypogonadism may occur more frequently as a result of the rising prevalence of postmenopausal illnesses, fueling market expansion. For instance, the United Nations Economic and Social Commission for Asia-Pacific, a regional agency with offices in Thailand, estimates that in 2021, more than 9% of the population would be women, or more than half of those over 65. This proportion of old women is projected to increase to more than 18% by 2050, or roughly by a factor of two. As postmenopausal disorders are becoming more common, there is an increase in the need for medications to treat hypogonadism because they lower testosterone levels. This element contributes to market expansion. The market is expanding as a result of several government efforts and product approvals. For instance, in 2019, the FDA approved Clarus Therapeutics' Jatenzo testosterone, an oral testosterone replacement treatment used to treat males with primary hypogonadism and hypogonadotropic hypogonadism. In addition, the FDA granted Antares Pharma permission to market Xyosted (testosterone enanthate) Injection in 2018. This contributes to the market's expansion.

Request A Sample@ https://qualiketresearch.com/request-sample/Hypogonadism-Drug-Market/request-sample

Market Restraints

Drugs for hypogonadism have a wide range of side effects. When women use hormone replacement treatment, they may experience local side effects such erratic heartbeat, breast swelling, dryness in the vagina, osteoporosis (weakening of the bones), and other problems. This constraint prevents market growth.  

Impact of COVID-19 The pandemic has caused a large number of hypogonadism patients to delay diagnosis and treatment, which has decreased the demand for hypogonadism medications. Demand for hypogonadism medications has decreased as a result of the pandemic's impact on many hypogonadism patients' delays in receiving a diagnosis and treatment. The pandemic's economic effects have caused several nations to cut back on healthcare spending, which has hurt the market for medications treating hypogonadism. Telemedicine has become more widely used as a result of the epidemic, which has decreased the necessity for in-person doctor appointments. The prescription and sales of hypogonadism medications have been impacted by this change.

 Market Segmentation

Global Hypogonadism Drug Market is segmented into Therapy, Drug Delivery, Type, Mechanism of Action, Route of Administration, and End User. By Therapy such as Testosterone Replacement Therapy, Gonadotropin, Gonadotropin-Releasing Hormones Therapy. By Drug Delivery such as Topical Gels, Injectable, Transdermal Patches, Others. By Type such as Hypergonadotropic Hypogonadism, Hypogonadotropic Hypogonadism. By Mechanism of Action such as Steroidal Androgens, Gonadotropins. By Route of Administration such as Oral, Injectable, Tropical. By End User such as Hospitals, Homecare, Specialty Clinics, Others.

Read More@ https://qualiketresearch.com/reports-details/Hypogonadism-Drug-Market

Regional Analysis       

Global Hypogonadism Drug Market is segmented five region Americas, Europe, Asia-Pacific, and the Middle East & Africa. Owing to the rising number of hypogonadism cases and increased public awareness of the hormonal illness, Asia-Pacific is anticipated to experience growth in the hypogonadism medicine market over the forecast period. Furthermore, in the coming years, it is anticipated that the region's market for hypogonadism medications will grow more rapidly due to the increase in the patient population. Due to the rising use of superior, highly advanced products, North America will continue to rule the market during the projection period. The expanding healthcare infrastructure and rising awareness of the hormonal illness with a wide range of treatment choices will both contribute to the growth of the hypogonadism drug market in the region over the course of the forecast period. 

Key Players

This report includes a list of numerous Key Players, namely AbbVie Inc. (U.S.), Bausch Health Companies Inc. (Canada), Sun Pharmaceuticals Industries Ltd. (India), Hikma Pharmaceuticals PLC (Japan), Amneal Pharmaceuticals LLC. (U.S.), Alvogen (U.S), Teva Pharmaceutical Industries Ltd (Israel), Endo Pharmaceuticals plc (Ireland), Perrigo Company plc (U.S.), Johnson & Johnson Services, Inc (U.S.).

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[trustedtablets911]

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