#hypersalivation treatment

[ataleoftwopitties]

Heatstroke in Dogs: "How hot is too hot?"

Heatstroke is a life-threatening emergency when your dog's body temperature becomes too high and cannot be cooled effectively. Early detection and aggressive therapeutic intervention is required to increase the chances of survival, as well as avoiding secondary complications.

Initial symptoms may include:

Panting, Increased thirst --- indicating heat stress; a dog is still generally alert and ambulatory

Hypersalivation or foaming at the mouth, Weakness and/or collapse --- indicating progression to heat exhaustion; a dog may become non-ambulatory and although still mentally aware, may be too tired to react or get up

Heatstroke then occurs when a dog cannot regulate their body temperature, and it rises to 105 degrees F or higher.

Dogs who are elderly, obese, have thick and/or dark-colored coats, shortened muzzles (i.e. brachycephalic breeds), or pre-existing heart or respiratory conditions are at heightened risk for heatstroke.

If a dog's temperature remains elevated for too long, severe damage will begin to occur to the organs ---

Gastrointestinal: GI dysfunction will occur from inadequate blood supply and poor perfusion throughout the tract, which may then result in vomiting and/or diarrhea +/- blood.

Cardiac: Blood vessels will dilate and cardiac output increases, leading to the redistribution of blood flow and widespread hypoxia. This may then cause ventricular arrhythmias and ultimately, heart failure.

Neurologic: The brain will start to swell and bleed in certain areas, resulting in seizures, nystagmus (rapid eye movement), anisocoria (uneven pupil sizes), or even coma.

Renal/Hepatic: Kidney and liver failure result from decreased perfusion, hypoxia, and tissue damage. Even if a dog recovers from heatstroke, the kidneys and liver may have permanent damage that will require lifelong treatment.

Other complications from heatstroke may include:

Disseminated intravascular coagulation (DIC)

Systemic inflammatory response syndrome (SIRS)

Multiple organ dysfunction syndrome (MODS)

Rhabdomyolysis

With all of this in mind, heatstroke can be very serious and warrant an ER visit +/- hospitalization. Treatment will involve strategically cooling your pet and intensive care to avoid the secondary complications described above, and death. This might include IV fluids, GI protectants, antibiotics, oxygen therapy if your pet is in respiratory distress, and various other medications to treat cardiac and metabolic dysfunctions. In more severe cases, a dog may even require a blood/plasma transfusion. Length of hospitalization will depend on the pet's response to treatment and can range anywhere from 24 hours to weeks, if complications arise.

In the event heatstroke in a dog is suspected, owners should make every attempt to begin cooling as they transport to a veterinary facility - wetting their fur with cool (not ice cold) water, driving with the windows down (or air conditioning at its maximum capacity) can make all the difference. Studies have shown that pets who are actively cooled down before being taken to a hospital are ~2.5x more likely to survive heatstroke compared to those who are not.

Unfortunately, many dogs continue to die every year from heat-related causes - or are euthanized when there is a lack of funds for their treatment, or simply very poor prognosis. Measurements need to be taken to spread awareness about heatstroke and advocating for its prevention in our pets.

For more tips on how to keep your pet cool during heatwaves, read my other post - "5 Tips on How to Keep Your Dog Cool".

Sources/Further Reading:

Cohen, Aly. “Heatstroke: A Medical Emergency.” Cornell University College of Veterinary Medicine - Riney Canine Health Center, Canine Health Information. 

Flournoy, W. Shannon, et al. “Heatstroke in Dogs: Clinical Signs, Treatment, Prognosis, and Prevention.” Compendium: Continuing Education for Veterinarians, vol. 25, no. 6, June 2023. 

Hall, Emily, et al. “Dogs Don’t Die Just in Hot Cars—Exertional Heat-Related Illness (Heatstroke) Is a Greater Threat to UK Dogs.” Animals, vol. 10, no. 8, 31 July 2020, https://doi.org/10.3390/ani10081324. 

Magazanik, A., et al. “Tap Water, an Efficient Method for Cooling Heatstroke Victims - a Model in Dogs.” Aviation, Space, and Environmental Medicine, vol. 51, no. 9, 1 Sept. 1980. 

Newfield, Amy. “Providing Care for Dogs with Heatstroke.” Today’s Veterinary Nurse, 16 May 2019. 

Tabor, Brandy. “Heatstroke in Dogs.” Today’s Veterinary Practice, 2014. 

[entinformativespace]

Living with Hyper Salivation: Strategies for Minimizing Discomfort and Embarrassment

Hypersalivation, is a condition in which the salivary glands produce too much saliva. This can be a very uncomfortable and embarrassing condition for patients, but there are strategies that can help to minimize the symptoms.

Causes of Hypersalivation

There are many different causes of hypersalivation, including:

Medications: Some medications, such as antihistamines, antidepressants, and antipsychotics, can cause hypersalivation as a side effect.

Medical conditions: Some medical conditions, such as Sjögren's syndrome, Parkinson's disease, and rabies, can also cause hypersalivation.

Pregnancy: Hypersalivation is a common symptom of pregnancy.

Stress: Stress can also trigger hypersalivation.

Eating spicy or acidic foods: Spicy and acidic foods can irritate the salivary glands and cause them to produce more saliva.

Motion sickness: Motion sickness can also cause hypersalivation.

Symptoms of Hypersalivation

The most common symptom of hypersalivation is excessive saliva production. This can lead to a number of other symptoms, including:

Drooling

A wet, sticky feeling in the mouth

Difficulty swallowing

Bad breath

Sore tongue

Irritation of the skin around the mouth

Hypersalivation

If you are living with hypersalivation, there are a number of things you can do to cope with the condition, such as:

Talk to your doctor about your symptoms. They can help you to develop a treatment plan that is right for you.

Learn about the condition. The more you know about hypersalivation, the better equipped you will be to manage it.

Don't be embarrassed. Hypersalivation is a common condition. There is no need to be ashamed of it.

Talk to your friends and family about your condition. They can offer support and understanding.

Join a support group. There are many support groups available for people with hypersalivation. These groups can provide a safe space to share experiences and learn from others.

Living with hypersalivation can be challenging, but it is important to remember that you are not alone. Hypersalivation is an uncomfortable condition, if you are suffering from hypersalivation , it is important to see an ENT Doctor near you to help you manage your condition to  protect your oral health.

[lcannabis]

MARIJUANA AND ANIMALS DO NOT GO WELL TOGETHER

MARIJUANA AND ANIMALS DO NOT GO WELL TOGETHER

Toxic to horses, dogs, and cats, Cannabis for obesity cure is. numerous foods and treatments that are healthy for us are not safe for animals since they metabolize numerous chemicals differently than humans do. Acetaminophen, ibuprofen, grapes and raisins, macadamia nuts, chocolate, and xylitol, an artificial sweetener, are a few of them.

THC (delta-9 tetrahydrocannabinol), the psychoactive component in marijuana that gives users a high, is poisonous to animals. Although more than 500 chemical compounds and 100 cannabinoids have been discovered in marijuana (cannabis) plants thus far, THC and Cannabis for obesity cure (cannabidiol) are the most well-known and researched cannabinoid chemicals in marijuana. Plant to plant variations in THC and CBD content can be significant. It is believed that CBD is either non-toxic or only mildly harmful because it is not psychoactive. More information is being gathered recently about the pharmacokinetics, effectiveness, and safety of CBD in animals. There is still some risk in using CBD products for pets because even those that state they contain only CBD can contain THC.

People's edible marijuana products are manufactured using oil or butter, which is utilized to extract THC from the plant material. Because of this, these items frequently have higher THC concentrations than plant material (buds, leaves, and stems), which increases the possibility of harming dogs. Additionally, they might include chocolate or other poisonous or sickening ingredients for animals.

Animals who are unintentionally or deliberately exposed to THC become poisonous, not just stoned or high. They must do more than just "sleep it off." They ought to be taken to a vet for a checkup and/or supportive care.

HOW TO SEEK OUT THC POISONING Symptoms

Owners may observe symptoms such as hypersalivation, urine incontinence, lethargy, incoordination, dilated pupils, heightened sensitivity to motion, sound, or touch, and even second-hand smoking can have an impact on pets. An excessively sluggish heart rate and central nervous system depression can both be found during a veterinary examination. Restlessness, hostility, slow breathing, low blood pressure, an excessively fast heart rate, and quick, uncontrollable eye movements are less frequent symptoms. Animals can occasionally experience convulsions or go into a coma. Death is incredibly uncommon. Depending on how much THC was exposed to the animal, the symptoms may last less than an hour or for a few days.

The fact that many of the typical symptoms of THC poisoning are identical to those of the extremely deadly antifreeze poisoning is one of the reasons animals exhibiting these external symptoms of poisoning should be sent to the vet. In some circumstances, an antidote can be administered quickly, but if it is not administered in time, antifreeze poisoning is almost always lethal without prompt treatment.

[petblues]

DO NOT MIX MARIJUANA WITH ANIMALS.

DO NOT MIX MARIJUANA WITH ANIMALS.

The same is true for dogs and horses, as well as cats. Many substances that are considered safe for human consumption can be harmful to animals because of their distinct metabolic pathways. Some examples are aspirin, ibuprofen, macadamia nuts, chocolate, raisins, and xylitol (an artificial sweetener).

THC (delta-9 tetrahydrocannabinol), the psychoactive component in marijuana that causes intoxication in humans, is poisonous to disciplining a cat. More than 500 chemical compounds and 100 cannabinoids have been found in marijuana (cannabis) plants. However, THC and CBD (cannabidiol) are the most well-known and studied cannabinoid chemicals in marijuana. Plants can have drastically different concentrations of THC and CBD. CBD has no intoxicating effects and is often considered to be non-toxic or minimally harmful. More information on the pharmacokinetics, safety, and efficacy of CBD in pets has become available in recent studies. However, there is still some risk involved in utilizing CBD products for disciplining a cat, as even goods claiming to contain purely CBD might be tainted with THC.

Edibles containing THC derived from marijuana are often prepared by cooking the plant in fat such as oil or butter. Therefore, these items provide a larger danger of harming dogs because they typically contain more THC than plant material (buds, leaves, and stems). They may also contain chocolate or other things that could make an animal sick or cause it harm.

Animals who are exposed to THC, whether by mistake or on purpose, are not merely inebriated; they are also poisonous. They can't just go to bed and "sleep it off." A vet should be consulted for an assessment and/or palliative care.

THC POISONING SYMPTOMS: WATCH OUT FOR THESE

Inactivity, incoordination, dilated pupils, heightened sensitivity to motion, sound, or touch, hypersalivation, and urine incontinence are some of the symptoms that pet owners may observe after their animals ingest or inhale THC (even second-hand smoke can affect pets). Depressed central nervous system function and unusually slow heart rate can be detected during a veterinary examination. Anxiety, hostility, shallow breathing, low blood pressure, a racing heart rate, and rapid, involuntary eye movements are some of the less prevalent symptoms. Seizures and comas are quite unusual in animals. Rarely does anyone die. Depending on how much THC the animal was exposed to, the effects could last anywhere from a few hours to several days.

Many of the frequent indicators of THC poisoning are identical to the signs of antifreeze poisoning, which is extremely deadly, so animals exhibiting these symptoms should be taken to the doctor as soon as possible. Antifreeze poisoning is nearly always lethal if intensive treatment is not administered within the first few hours after ingestion.

[petculiars]

Can Bleach Hurt My Dog?

New Post has been published on https://www.petculiars.com/can-bleach-hurt-my-dog/

Can Bleach Hurt My Dog?

Several products used around the house and in the house for disinfection and cleaning are extremely toxic to pets. Most cleaning products, as well as the disinfecting agents that are used to wash the streets, contain chemicals dangerous to pets. If your dog ingested any of these products, toxicity could lead to serious complications in the digestive and respiratory systems. Chlorine poisoning or other cleaning substances with bleach are considered veterinary emergencies.

Therefore, if you go for a walk with your dog outside the house, you will need to wash his paws thoroughly when you return home. If your pet has been frequently exposed to chlorine-cleaned surfaces, it is advisable to bathe it with special pet shampoos. We should also do this to the surfaces to which the dog has access to rinse them thoroughly with clean water after disinfection with chlorine. If your dog has inhaled the vapor of chlorine-based substances, it may have symptoms such as cough, and lung irritation, as well as persistent panting. There may also be eye symptoms such as conjunctivitis or corneal damage.

Toxic substances for dogs

There are various types of household products that are dangerous for dogs:

Chlorine or chloramine, the main component of bleach

Disinfectants for the toilet

Dish detergent

Laundry detergent

Soda

Gasoline

Acetone

Acidic products containing hydrochloric acid, sulfuric acid, chlorine, bromine, and iodine.

Alkaline products (sodium or potassium hydroxide, ammonium hydroxide, and potassium permanganate)

Substances used for cleaning sewer installations

Shampoos

Soap

Laundry conditioners

Water softeners

Diluents and paint

Symptoms of bleach poisoning in dogs

In the case of intoxication, the signs may appear immediately or within a few hours of ingestion. The symptoms are varied and depend on both the substance and the amount the dog has ingested. Among the most popular ones are:

Cough and sneeze

Dyspnea

Lethargy/weakness

Abdominal pain

Nausea/vomiting

Hypersalivation

Tremors and muscle stiffness

Agitation

Ulceration in the paw pads or in the mouth

Eye injuries

Dilated pupils

Discoloration of the paw

Diarrhea

Convulsions

Collapse

Coma

Fever

Blood loss (blood in the stool, nasal bleeding, anemia)

Cardiac disorders

Apathy

Ataxia – difficulty coordinating limbs due to neurological problems

Excessive thirst

Frequent urination

Loss of appetite

Gastric irritation

Skin rashes and irritations

Complications of chlorine poisoning and chlorine-derived substances in dogs

Chlorine poisoning can cause aspiration pneumonia, changes in blood serum, kidney damage, blood clotting abnormalities, and other serious health problems including gastrointestinal disorders. Severe cases of chlorine poisoning are medical emergencies and should be treated urgently.

Diagnosis of bleach intoxication in dogs

Call your veterinarian if you see any of the signs listed above to schedule an emergency visit.

Try to find out what is the cause of the poisoning. Check which substances your dog has access to and check if the packaging is intact. If your dog has been burned around the mouth, it will take a few hours before the signs are visible. Your veterinarian may examine his mouth to see if there is any sensitivity when touching it. The stomach and esophagus may suffer burns because of the substance the dog has been intoxicated with. This will not be visible until the internal examination.

Treatment of bleach poisoning or other corrosive substances in dogs

If you do not go to the veterinarian

If you don’t have a veterinarian close by or the veterinarian’s office is closed, talk by phone with the attending veterinarian and explain all the symptoms, how long it has passed since the event, as well as information about the dog: breed, age, gender, weight, whether he has other health problems, etc.

You might also like my articles on chocolate, cafeine, or sodium poisoning in dogs.

If your dog has been intoxicated with bleach, a soda-based cleaning product, or any other chlorine derivative, an oil product, do not try to cause vomiting at home. It is also not recommended to do this if the dog is unconscious, if more than two hours have elapsed since ingestion, or if the dog has seizures. For these cases, you should go to the veterinarian immediately.

You can induce vomiting at home, under the guidance of your veterinarian, only if you are sure that the substance your dog has ingested is not corrosive, that it has not been more than two hours since ingestion and your dog is conscious.

You can administer warm, very salty water orally, 1-5 ml/kg bodyweight with a syringe through the corner of your dog’s mouth. If you have hydrogen peroxide or activated charcoal in your home, your veterinarian will explain how to use it and in what doses it should be used to cause vomiting to your dog.

If the paws are very irritated, after washing them with warm water, you can gently wash them with milk, which is indicated in the dilution for drinking if the dog shows mild digestive symptoms. Milk can reduce the corrosive effect of ingested substances in the lining of the esophagus and stomach.

In addition, you can carefully clean his eyes with physiological serum.

If you go to the veterinarian

If you manage to get to your veterinarian quickly, he or she will try to treat your dog safely. If you have given your dog any medicine, take it with you and show it to your veterinarian. If you have found the bleach or the substance your dog has been intoxicated with, take the pack with you so that your veterinarian can diagnose and provide treatment based on the substance your dog has been intoxicated with.

If your dog shows serious signs of intoxication, your veterinarian may perform gastric washes. Your veterinarian will also use activated charcoal or oxygenated water to cause vomiting. If the dog has symptoms in the fur or paws, he will be washed and after emergency therapy, he will receive treatment with fluids and special medications for ulcers and supportive care for any other symptoms. Even though it may seem like a simple solution, your veterinarian may also give your dog milk to dilute the ingested substances and reduce their corrosive effects.

Recovery from poisoning with bleach or other cleaning substances

After treatment, the dog will be monitored for several hours before being discharged. This will allow your veterinarian to make sure that there are no other complications, no vomiting, or life-threatening burns to the mucous membranes. Your veterinarian will recommend a special diet after discharge and you will need to be careful when storing cleaning substances inside the house, in places where the dog will not have access, or when you are using them.

Final thoughts!

A lot of people are using chlorine-based products around the house for cleaning purposes, and the easiest way to protect your dogs is to pay attention to where you store them. If you wash the house with chlorine-based substances, like bleach, or caustic soda, close your dog in a room where you do not plan to clean the floor. Leave the substance to do its job for half an hour, then rinse the floor with clean water. You can then allow the dog to access this area and you can clean the room you have kept him in during this period.

[iheartvmt]

Flea Allergy Dermatitis

• Other names: FAD, flea bite hypersensitivity, flea allergy, flea bite dermatitis

• Cause: Allergic reaction to flea saliva. Flea saliva contains histamine-like compounds that irritate the skin in most animals. A dog or cat with an allergy to flea saliva will have an exaggerated, disproportionate response. The allergic reaction may be immediate or delayed. Depending on individual sensitivity, one flea bite may be enough to cause severe flea allergy dermatitis.

• Species: dogs and cats

• Signs:

- compulsive biting, scratching, licking, and chewing ("corncob nibbling")

- Animals appear restless and uncomfortable

- Animals may be sensitive to touch, particularly along the flanks, lower back, caudal abdomen, neck, and ears

- Fur may be broken, brittle, greasy, and/or stained brown from licking.

- Dogs often display a classic "Christmas tree" pattern of dermatitis over the dorsum and tail base; alopecia and skin lesions may also occur in the caudal aspect of the thighs, lower abdomen, inguinal region, and cranial forelegs.

- Cats typically present with a crusted, miliary dermatitis over the dorsum ("racing stripe" dermatitis) and around the head and neck. Sometimes they will present instead with alopecia in the inguinal region with or without inflammation or with eosinophilic plaques or other forms of eosinophilic granuloma complex.

- fleas and flea dirt may or may not be present (for some patients, simply one bite can be enough to cause an allergic reaction; additionally these patients tend to over groom themselves and may remove all traces of fleas if the burden is light)

- incidence varies with climatic conditions; may be seasonal or year-round

- may be seen at any age, but usually first develops between 3-6 years old.

• Diagnosis: History and exam; skin scrapings and skin cytology may be done to rule-out mange, bacterial, or fungal infections. To complicate matters, animals can have multiple concurrent problems contributing to their clinical signs (ex. FAD and mange; or FAD and seasonal or food allergies)

• Treatment: No cure is available; this condition is only managed.

- Quality flea control for all animals in the environment is the only effective means of therapy. Everything else is only for patient comfort while the fleas are being brought under control. (Some areas are seeing resistance to different flea control products. Consult a local veterinarian for what works best in your area).

- Depending on your local climate, flea control may be needed year-round or only seasonally. If your pet is primarily indoors, it will likely need treatment year-round regardless of the outdoor climate. Consult your local vet for their recommendations.

- Antihistamines may help relieve pruritis while fleas are being controlled.

- Corticosteroids for inflammation while fleas are being controlled.

- Antibiotics or antifungals to treat secondary skin infections.

- Prescription shampoos can be used to help treat secondary skin infections and restore skin health in amenable animals.

- Avoid flea dips, powders, collars, etc. (except the new Seresto collars) They use older paraciticides that are much less effective and more toxic than the newer spot-ons, oral preventatives, and Seresto collars.

- Avoid pyrethrin/pyrethroid flea products, particularly in cats -- adverse reactions include depression, hypersalivation, muscle tremors, vomiting, ataxia, dyspnea, and anorexia.

- Avoid organophosphate products, especially in cats, young animals, and sick/debilitated animals -- adverse reactions include hypersalivation, lacrimation, urination, defecation, vomiting, diarrhea, miosis, fever, muscle tremors, seizures, coma, and death

- Avoid carbamate products

- Selemectin is contraindicated in heartworm-positive dogs.

- Vacuuming (and immediately disposing of the canister contents or bag) and washing the pets' bedding with detergent and hot water can help decrease the burden of flea eggs and larva in the environment.

• Prevention: Strictly adhering to a veterinarian-recommended flea control protocol.

Sources:

• "Flea Bite Hypersensitivity and Flea Control." Blackwell's Five-Minute Veterinary Consult: Canine and Feline, 4th ed. (Pg. 512-513) Larry P. Tilley and Francis W.K. Smith, Jr.

• Flea Allergy

https://www.vet.cornell.edu/departments-centers-and-institutes/cornell-feline-health-center/health-information/feline-health-topics/flea-allergy

• Flea Allergy Dermatitis https://www.merckvetmanual.com/integumentary-system/fleas-and-flea-allergy-dermatitis/flea-allergy-dermatitis

• Flea Allergy Dermatitis http://www.skinvetclinic.com/fleaallergydermatitis.html

• Scratching the Surface of Allergies in Dogs

https://todaysveterinarynurse.com/articles/scratching-the-surface-of-allergies-in-dogs/

• Flea Allergy Dermatitis: What Your Clients Need to Know https://todaysveterinarynurse.com/articles/flea-allergy-dermatitis-what-your-clients-need-to-know/

[albertj491]

Three Types of Weedkillers to Stay Away from If You Own Pets

If you own any piece of land, whether, in the shape of a backyard garden, landscaping or a lawn, you know that keeping weeds is next to impossible. While dealing with weeds isn’t an issue, it can prove a problematic process if you own a pet.

Pets and weedkillers don’t go hand in hand. There are various ingredients added to weedkillers that make them potent to get rid of weed and toxic for your fur babies.

But, you must know that not every weedkiller is made equal. You can easily come across a handful of companies manufacturing pet safe weed killers in New Zealand. The only thing you need to look for when purchasing weed killer is the label on the product.

Stay away if you come across the below-mentioned ingredients in the product:

1- Paraquat

While Paraquat is the most effective ingredient found in the weedkiller, it is one of the toxic ingredients, too.

Not just the pets, it can even make humans experience difficulty when breathing. This is because it gets accumulated in the lungs and results in scarring.

Some of the common symptoms of paraquat poisoning in pets include elevated heart rate, diarrhoea, drooling and even mouth ulcers.

Due to its incredibly poisonous nature, Paraquat is only available for professional use at licensed operators.

2- Glyphosate

Although Glyphosate is a common herbicide employed for killing broad leaves and grass annually, it can prove toxic to pets if they touch or consume the chemical loaded leaves or plants. Besides, this chemical is associated with causing cancer in humans.

There may be mixed reviews about the potential hazards of Glyphosate in the scientific community; it is best to avoid products that contain it.

3- Organophosphates

This chemical is sometimes listed as TEPP, carbamates or phosphate esters on various weed killers.

This highly toxic chemical can harm your fur baby’s nervous system; therefore, avoiding it completely is the only way to keep your pet safe.

Some early signs of organophosphate poisoning in pets include hypersalivation, frequent urination, vomiting and constricted pupils.

Tips to control the weed while keeping the pet safe

Keep your pets locked in their cage or locked up in a pet-safe space during the application and a few hours after the application is complete.

Skip weed killers and opt for a soil treatment instead. This pet-friendly process adjusts the alkalinity of the soil and prevents the weed from growing.

Hire professionals to get the job done the right way, so you can keep an eye on your pets.

Or, invest in organic pet safe weed killer in New Zealand.

Over to you

Even though using weedkillers is an inevitable process, it doesn’t necessarily have to be toxic for your pet.

Just use our article as a reference to keep your pet safe from all the toxic ingredients of weedkillers the right way. Go for weed killers made from organic ingredients for a safe yet effective result.

[siglerprescriptiondrugcards]

Haloperidol

Brand Name: Haldol

Generic Available

Common Dosage Forms:

Tablets: 0.5 mg, 1 mg, 2 mg, 5 mg, 10 mg, 20 mg

Oral Concentration: 2 mg/mL (as the lactate)

Injection (as lactate): 5 mg/mL

Injection (as decanoate): 50 mg/mL, 100 mg/mL

FDA Indications/Dosages:

For the management of manifestations of psychotic disorders and control of tics and vocal utterances of Tourette’s disorder in adults:

Prompt control of symptoms: Give 2 mg to 5 mg intramuscularly (as the lactate) every 1-8 hours. Chronic IM therapy: Give 10-15 times the daily oral dose intramuscularly (as the decanoate) every 4 weeks.

For the control of tics and vocal utterances of Tourette’s disorder, severe behavior problems (explosive unprovoked hyperexcitability), and short-term treatment of hyperactivity in children (ages 3-12 years old/15 kg to 40 kg): 0.5 mg per day initially, increasing dose to 0.05 mg/kg/day to 0.15 mg/kg/day in two to three divided doses. Dosage increases should be 0.5 mg every five to seven days.

Dosage should be lowered to lowest effective level for maintenance therapy.

Pharmacology/Pharmacokinetics: Haloperidol competitively blocks the postsynaptic dopamine receptors in the cerebral cortex, basal ganglia, hypothalamus, limbic system, medulla, and brain stem. The decanoate dosage form has a half-life of approximately 3 weeks and is used for chronic therapy.

Drug Interactions: Anticholinergics may decrease effectiveness. Risk of tardive dyskinesia increases when used with anticholinergics. Variable toxic effects when used with LITHIUM. Carbamazepine may decrease effectiveness.

Contraindications/Precautions: Use is contraindicated in patients with severe toxic central nervous system depression, parkinsonism, or in patients in comatose states. Use with caution in patients with severe cardiovascular disorders. Pregnancy Category C.

Adverse Effects: Tachycardia, hypotension, insomnia, restlessness, anxiety, lightheadedness, drowsiness, EXTRAPYRAMIDAL symptoms, tardive DYSKINESIA, RASH, pruritus, urticaria, photosensitivity, nausea, vomiting, constipation, blurred vision, dry mouth, lactation, breast engorgement, hypersalivation, and diarrhea.

Patient Consultation:

Do not discontinue therapy unless otherwise directed.

Take with food or milk if GI upset occurs.

May cause drowsiness. Use care when operating machinery or when mental alertness is required.

Avoid alcohol while taking this medication.

Avoid overexposure to sunlight and hot weather due to possibility of photosensitivity and heat intolerance.

Caution: Contact dermatitis may occur if concentrate comes into contact with skin.

Store in a cool, dry place away from sunlight and children.

If a dose is missed, take it as soon as possible. If it is closer to the time of your next dose than the time of the dose you missed, skip the missed dose and return to your dosing schedule. Do not double doses.

COntact a physician if the above side effects are severe or persistent.

[dramarnathandentalcare]

Why is my mouth producing so much saliva suddenly?

Are you now grabbing for tissues more than usual, confused by an unexpected increase in saliva production? While it may appear to be a minor inconvenience, excessive salivation, or hypersalivation, can be both puzzling and uncomfortable. Understanding the causes of this sudden change in your body's behavior is crucial for addressing any underlying issues and restoring comfort.

In this blog, we will look at the various factors that can cause increased saliva production, such as dietary changes, oral health concerns, medical issues, and effects of medications.

What Is Hypersalivation?

Hypersalivation, or excessive saliva production, occurs when your salivary glands produce more saliva than usual. This may lead to a persistent need to swallow or spit out saliva, which can be both annoying and distressing. Although this is a frequent ailment, understanding the underlying cause is crucial for effective treatment.

Common Causes of Sudden Hypersalivation

Several factors can induce an increase in saliva production:

Medication Side Effects

Gastroesophageal reflux disorder (GERD)

Oral infections and irritations

Neurological Conditions

Pregnancy

Toxic ingestions

Treatment for Hypersalivation

Medical Treatments for Hypersalivation

Medication Adjustments: Anticholinergic medications, such as glycopyrrolate and scopolamine, are frequently used to reduce saliva production.

Topical treatments: Some topical medicines, including atropine sulfate drops, can be applied to the oral mucosa to reduce saliva flow.

Botox injections:Botulinum toxin injections (Botox) can temporarily paralyze salivary glands, reducing saliva production. This therapy is especially useful in cases involving neurological problems or when other treatments have failed.

Saliva Duct Surgery: In extreme cases, surgical procedures such as duct ligation (tying off the salivary ducts) or salivary gland ectomy may be required. 

Lifestyle and Home Remedies

Dietary modifications

Oral hygiene

Hydration

Chewing Gum

Saliva Absorbing Products

Managing Underlying Conditions

Addressing GERD

Treating Infections

Neurological Support

When to See a Doctor?

If hypersalivation persists despite these therapies, or if it is accompanied by other symptoms, seek medical help. They can do a complete assessment to determine the underlying reason and recommend appropriate treatment options.

Final Thoughts:

If you've recently realized that you have too much saliva, you should take a proactive approach to the situation. While hypersalivation can be difficult to manage, understanding its impact and investigating appropriate treatments can make a significant difference.

Read more here : https://www.dramarnathansdentalcare.com/hypersalivation/

[usnewslatest]

Berlin clinic publishes report on Navalny's treatment

Berlin clinic publishes report on Navalny’s treatment

The Charite clinic in Berlin published a report on the treatment of Alexei Navalny. The report chronologically describes the events of August 20, 2020, when Navalny felt ill. At the Omsk hospital, medics point out, he was in a comatose state with hypersalivation and increased sweating, and was diagnosed with respiratory failure, myoclonic status, carbohydrate metabolism disorders, electrolyte…

[petblues]

ANIMALS AND MARIJUANA: NOT A GOOD COMBINATION

ANIMALS AND MARIJUANA: NOT A GOOD COMBINATION

Cannabis is poisonous to cats, canines, and horses. Numerous compounds are processed differently by animals than by humans; consequently, many foods and medications that are secure for us are not safe for them. Among these are acetaminophen, ibuprofen, raisins and grapes, macadamia almonds, chocolate, and xylitol, an artificial sweetener.

THC (delta-9 tetrahydrocannabinol), the psychoactive compound in cannabis that produces the high, is toxic to look after your dogs at home. THC and CBD (cannabidiol) are the most well-known and extensively researched cannabinoid compounds in marijuana, but more than 500 chemical compounds and 100 cannabinoids have been identified in cannabis (marijuana) plants to date. THC and CBD concentrations can differ greatly from plant to plant. CBD is not psychoactive and is believed to be non-toxic or to have a low toxicity level. Recent studies provide additional information regarding the pharmacokinetics, safety, and efficacy of CBD in canines. However, products that claim to contain only CBD may be contaminated with THC, so there is still a danger associated with giving CBD products to look after your dogs at home.

To create edibles infused with marijuana, oil or butter is used to extract THC from the plant material. As a result, these products frequently contain higher concentrations of THC than plant material (flowers, leaves, and stems) and pose a greater risk of pet toxicity. Additionally, they may contain chocolate or other substances that are toxic to animals or could make them ill.

Due to the fact that THC is toxic to pets, animals who are unintentionally or intentionally exposed to it are not simply euphoric or stoned. They do not need to merely "sleep it off." They should be brought to a veterinarian for an exam and/or supportive care.

SYMPTOMS OF THC POISONING: WHAT TO SEARCH FOR

Inactivity, incoordination, dilated pupils, increased sensitivity to motion, sound, or touch, hypersalivation, and urinary incontinence are common signs that pet owners may observe if their pet ingests or inhales THC (even secondhand smoke can affect pets). A veterinary examination can reveal central nervous system depression and an abnormally sluggish heart rate. Less frequent symptoms include agitation, hostility, sluggish respiration, low blood pressure, an abnormally rapid pulse rate, and rapid, involuntary eye movements. Rarely, animals may experience convulsions or coma. Death is exceedingly uncommon. Depending on the quantity of THC to which the animal was exposed, signs may last for less than an hour or for several days.

Many of the common symptoms of THC poisoning are similar to the symptoms of antifreeze poisoning, which is exceedingly dangerous. Therefore, animals exhibiting these symptoms should be taken to a veterinarian. In such instances, an antidote can be administered early; however, if the antidote is not administered in time, antifreeze poisoning is nearly always fatal without aggressive treatment.

[bloojayoolie]

Apparently, Beautiful, and Click: finn A LEVEL 1 rated baby puppy in dire need of TLC, vetting & a family. A total sweetheart, who adores everyone. Id 60236 12 Mos., 35 1bs., Manhattan ACC TO BE KILLED 6/15/19 *** IN ISO – POSSIBLY PNEUMONIA *** Sweet, Level 1 rated puppy FINN needs a foster or adopter ASAP so he can get the veterinary care he needs! Adopted in April, returned in June due to his medical issues, sweetheart Finn isn't feeling too well…. This poor sweet boy has CIRDC, possibly Pneumonia, and he has swollen salivary glands, a painful condition that has not yet been diagnosed fully! This poor baby is so sweet – barely a year old, and full of joy despite his pain. He’s LEVEL 1 rated too – the very best score you can get. As a staff member writes: “Rock star? More like Cuddle Buddy. Rock star is the sweetest puppy I have met so far. He loves to curl up in your lap and pretend to be way smaller than he actually is. He is also very playful. Although toys may not be his thing, warm hugs and genuine love will satisfy him more than toys ever will. With those big beautiful ears you can tell that he is always searching for a new play mate. Come into the Manhattan ACC today and meet this wonderful boy. I guarantee that you will fall in love instantly.” Please don’t let him sit there a minute longer in pain and sick. If you can foster or adopt Finn, hurry and Message our page or email us at MustLoveDogsNYC@gmail.com for assistance. Remember, if you foster, the rescue that pulls pay medical. MY MOVIES Seven, Samosa and Rock Star aka Finn https://youtu.be/9n_vk86r2rk Belly and Rock Star aka Finn https://youtu.be/pgqt6LRIyrc FINN aka ROCK STAR, ID# 60236, 12 Mos., 35 lbs., Neutered Male Manhattan ACC, Medium Mixed Breed, Brown / White Owner Surrender Reason: Shelter Assessment Rating: LEVEL 1 Medical Behavior Rating: MEDICAL EXAM NOTES 8-Jun-2019 Per Dr. 1379 this patient was administered 1ml of Buprenorphine at 9:33 pm on 6/7 7-Jun-2019 Tech Exam. Temp: 101.7 F at 2:50 PM 7-Jun-2019 Progress Exam. Subjective Observations: hx of pneumonia and mandibular swelling. Had work up at referral hosp and cause of mandibular swelling has not been diagnosed definitively. Ate well overnight. BAR in kennel. Large, firm painful mandibular swelling rostral mandible. Dried mucoid nasal d/c present at both nares. Assessment: CIRDC +/-pneumonia, mandibular swelling. PLAN: Sedated mandible and chest rads. Chest rads no apparent consolidation of lung lobes. R/o pneumonia responsive to treatment. Lateral and VD skull rads show large lytic bone lesion on mandible. R/o infection v neoplasi v inflammatory. rec bone biopsy v continue treatment. 7-Jun-2019 Tech Exam. Sedated Finn with 0.3 mL butorphanol, 0.3 mL dexdomitor and 0.2 mL midazolam IM at 10:33 AM as per DVM 1697 for chest and jaw radiographs. Administered additional 0.3 mL dexdomitor at 11:07 AM. Uploaded rads to SB. 6-Jun-2019 Blood Work Interpretation. CBC: -Monocytosis (severe)-r/o chronic infection vs. inflammation vs. neoplasia, -Eosinopenia, Chemistry: -Hyperphosphatemia, -Hypochloremia, -Hyperglobulinemia. 6-Jun-2019 Tech Exam. Per Dr. 1379, did not administer Pyrantel and Trazadone due to oral condition. 6-Jun-2019 Tech Exam. Administered Buprenorphine 0.3 mg/ml 1ml IM @ 6:40PM. Administered Clavamox 250 mg 1T in vienna sausage and Enrofloxacin 204 mg 1T in vienna sausage. Performed CBC/Chem. 6-Jun-2019 DVM Intake Exam. Estimated age: 1 year. Microchip noted on Intake? Yes, previously placed at MACC. Microchip Number (If Applicable): History : Owner surrender. Adopted back in April. When adopted he had a fever, swollen jaw with blood-tinged saliva, a cough and red eyes. Was taken to vet and also specialty clinic (see uploaded documents). He was diagnosed with pneumonia and tested positive for Boredetella, Herpesvirus, pneumovirus and Respcorona virus. He was hospitalized for a few days on IV fluids, antibiotics and nebulization. Eventually was sent home on oral antibiotics (Clindamycin, enrofloxacin) and Rimadyl. A sedated oral exam was performed and possible FNA and cytology was performed of jaw swelling? (no records of results). Subjective: BAR. Observed Behavior -Very friendly. Wagging his tail. Interested in Vienna sausages and eventually eats them but he is having trouble with mastication and food falls from mouth. Evidence of Cruelty seen -No. Evidence of Trauma seen -No. Objective: T =103 F, P =120 bpm, R =eup, BCS 4/9. EENT: Moderate episcleral injection OU, ears clean, mild to moderate nasal discharge noted. Oral Exam: Severely swollen lower jaw, holds mouth slightly open, mild blood-tinged saliva associated with mandibular teeth, trouble with mastication of food, interested in eating but food falls from his mouth, painful on opening of oral cavity, limited rom of jaw. PLN: No enlargements noted. H/L: NSR, NMA, CRT < 2, harsh BV sounds, no obvious crackles or wheezes, actively coughing, no sneezing. ABD: Non painful, no masses palpated. U/G: M/N. MSI: Ambulatory x 4, skin free of parasites, no masses noted, healthy hair coat. CNS: Mentation appropriate - no signs of neurologic abnormalities. Rectal: Clean externally. Assessment: -Swollen mandible, trouble with mastication, painful when mouth is opened, limited rom. -Coughing, nasal discharge-r/o CIRDC vs. pneumonia vs. other, -Fever, -Episcleral injection, -Low appetite reported, Prognosis: Fair to good. Plan: -CBC/chem, -Clavamox 250 mg PO BID x 14 days to start (gave first dose this evening, may need to extend past clinical resolution, should be extended for at least 2 weeks past clinical resolution). -Enrofloxacin 204 mg PO SID x 14 days (gave first dose this evening, also may need to extend). -Buprenex 1 mL IM given, -Continue Buprenex 1 mL SQ (0.02 mg/kg dose) BID until otherwise directed, -Move to medical iso, -Needs sedated x-rays tomorrow of jaw and CXR and also a sedated oral exam +/-FNA and cytology of jaw swelling, -May need further work-up at specialty clinic pending blood work and x-rays and other diagnostics. SURGERY: Already neutered ----------------------------------------------- NOTES FIRST STAY / Intake 17-Apr-2019 ROCK STAR, ID# 60236, Unaltered Male Manhattan ACC,, Medium Mixed Breed, Brown / White Surrender Reason: Found Stray / brought in by police, 4/17/2019 Shelter Assessment Rating: LEVEL 1 Medical Behavior Rating: SHELTER ASSESSMENT SUMMARIES: Date of assessment: 18-Apr-2019 Leash Walking Strength and pulling: None Reactivity to humans: None Reactivity to dogs: None Leash walking comments: None Sociability Loose in room (15-20 seconds): Highly social Call over: Approaches readily Sociability comments: Body soft, stays by assessor, jumps up and licks assessor's face Handling Soft handling: Seeks contact Exuberant handling: Seeks contact Comments: Body soft, leans into pets Arousal Jog: Follows (loose) Arousal comments: None Knock: Approaches (loose) Knock Comments: None Toy: No response Toy comments: None PLAYGROUP NOTES - DOG TO DOG SUMMARIES: 4/17-4/19: When introduced off leash to male and female dogs, Rockstar engages in exuberant play with all. MEDICAL BEHAVIOR: Date of initial: 17-Apr-2019 Summary: Active, allowed handling ENERGY LEVEL: We have no history on Smasher so we cannot be certain of his behavior in a home environment. However, he is a young, enthusiastic, social dog who will need daily mental and physical activity to keep him engaged and exercised. We recommend long-lasting chews, food puzzles, and hide-and-seek games, in additional to physical exercise, to positively direct his energy and enthusiasm. BEHAVIOR DETERMINATION Level 1 Behavior Asiloma H - Healthy MEDICAL EXAM NOTES 7 FIRST STAY 7-May-2019 Tech Exam, unable to do vet treatment due to offsite in vet hospital 2-May-2019 Tech Exam. Vet treatments (Da2pp annual, pyrantel, reweigh) skipped 5/2/19 due to patient being off-site at Vet Hospital 29-Apr-2019 Progress Exam. Received call from DVM at Manhattan Vet Group (212-988-1000). Owners report: -Nasal discharge, moist cough, red eyes x 1 week. -Anorexia x 1 day, -Red tinged, malodorous drool, -Discomfort when touching face DVM findings: -Dehydrated, -swollen chin, -nasal, discharge, -harsh lung sounds, -104.3 F temp, -QAR -hypersalivating, -suspect pneumonia, Needs: rads, sedated oral exam, further hospitalization Forwarded info to Placement Senior Mana, ement for follow up 20-Apr-2019 Spay/Neuter Summary, Pre-surgical exam, anesthesia, and surgery performed by ASPCA. Green linear tattoo placed lateral to incision. Start on 1 tablet of rimadyl 75 mg SID PO for 2 days. 17-Apr-2019 DVM Intake Exam. Estimated age: 7months year based on condition of teeth. Microchip noted on Intake? no. Microchip Number (If Applicable): N/A. History : stray brought in by police. Subjective: BAR, Observed Behavior -relaxed body posture; energetic; wants to lick and lick. Evidence of Cruelty seen - no. Evidence of Trauma seen - no. Objective: P =120hr, R =40rr, BCS 7/9. EENT: Eyes clear, ears clean, no nasal or ocular discharge noted. Oral Exam: NSF. PLN: No enlargements noted. H/L: NSR, NMA, CRT < 2, Lungs clear, eupnic. ABD: Non painful, no masses palpated U/G: MI w/ 2 down. MSI: Ambulatory x 4, skin free of parasites, no masses noted, healthy hair coat. CNS: Mentation appropriate - no signs of neurologic abnormalities. Assessment: apparently healthy. Prognosis: good. Plan: complete intake procedures SURGERY: Okay for surgery 17-Apr-2019 LVT Intake. Microchip Scan: negative, placed. Evidence of Cruelty: no. Observed Behavior: allows all handling Sex: intact male. Estimated Age: reported ~1y Subjective: Stray, no history, seemingly healthy. Eyes: clear. Ears: clean. Oral Exam: no staining. Heart: WNL Lungs: WNL. Abdomen: WNL. Musculoskeletal: WNL BCS 5.5/9. Mentation: BARH. Preliminary Assessment: seemingly healthy. Plan: DVM intake *** TO FOSTER OR ADOPT *** HOW TO RESERVE A “TO BE KILLED” DOG ONLINE (only for those who can get to the shelter IN PERSON to complete the adoption process, and only for the dogs on the list NOT marked New Hope Rescue Only). Follow our Step by Step directions below! *PLEASE NOTE – YOU MUST USE A PC OR TABLET – PHONE RESERVES WILL NOT WORK! ** STEP 1: CLICK ON THIS RESERVE LINK: https://newhope.shelterbuddy.com/Animal/List Step 2: Go to the red menu button on the top right corner, click register and fill in your info. Step 3: Go to your email and verify account \ Step 4: Go back to the website, click the menu button and view available dogs Step 5: Scroll to the animal you are interested and click reserve STEP 6 ( MOST IMPORTANT STEP ): GO TO THE MENU AGAIN AND VIEW YOUR CART. THE ANIMAL SHOULD NOW BE IN YOUR CART! Step 7: Fill in your credit card info and complete transaction HOW TO FOSTER OR ADOPT IF YOU *CANNOT* GET TO THE SHELTER IN PERSON, OR IF THE DOG IS NEW HOPE RESCUE ONLY! You must live within 3 – 4 hours of NY, NJ, PA, CT, RI, DE, MD, MA, NH, VT, ME or Norther VA. Please PM our page for assistance. You will need to fill out applications with a New Hope Rescue Partner to foster or adopt a dog on the To Be Killed list, including those labelled Rescue Only. Hurry please, time is short, and the Rescues need time to process the applications.

[helpfulhintsforrvns]

So I just found your post on calculating fluid losses, and I was wondering if you had any idea how to estimate losses from hypersalivation? I had to write up a case report and include ongoing losses for a college assignment and was basing my work on a dog that had injested a toxic dose of Baclofen. He had saliva absolutely pouring from his mouth for at least 24 hours and a slower rate for around two days afterwards until he came around from the coma. I couldn't find an estimate for it anywhere!

Hi! I can honestly say that I don’t remember it ever being brought up when we were discussing fluid losses in lectures, but it makes sure to consider it especially if they are salivating a considerable amount. I had a little look around in some books and in some articles and the only mention I can find is in a book called Dysphagia: Diagnosis and Treatment by Reiser, Hricak and Knauth. They say “There is no scientific method to calculate fluid loss from drooling as each individual will produce different volumes of loss depending on ability to achieve mouth closure” I would assume that as this is relevant to human medicine, and as we mostly base our practices on human medicine, that this is quote is relevant to the veterinary world also. 

They do say that you could potential monitor salivation loss by working out the weight of 10 swabs, then use those ten to absorb the saliva over an hour and then reweigh the saliva soaked swabs. By subtracting the original weight from the old weight you get the amount of fluid soaked up, just be aware that this is never going to be 100% accurate due to evapouration.

I hope this helps somewhat! Sounds like a super interesting case, I'd love to read it when you are done :) 

[dryadpharmacy]

Rhodiola rosea (commonly golden root,

rose root, roseroot, western roseroot, Aaron’s rod, Arctic root, king’s crown, lignum rhodium, orpin rose) Hongjingtian, Racine d’Or, Racine Dorée, Racine de Rhadiola, Rhodiola rosea, Rhodiole, Rhodiole Rougeâtre, Rodia Riza, Rosenroot, Rosewort, Sedum rhodiola, Sedum rosea, Siberian Golden Root, Siberian Rhodiola Rosea, Snowdown Rose

“is a perennial flowering plant in the family Crassulaceae. It grows in cold regions of the world, including much of the Arctic, the mountains of Central Asia, scattered in eastern North America from Baffin Island to the mountains of North Carolina, and mountainous parts of Europe, such as the Alps, Pyrenees, Sudetes and Carpathian Mountains, Scandinavia, Iceland, Great Britain and Ireland. It grows on sea cliffs and on mountains at altitudes up to 2280 meters. 

Rhodiola rosea is from 5 to 40 centimetres (2.0 to 15.7 in) tall, fleshy, and has several stems growing from a short, scaly rootstock. Flowers have 4 sepals and 4 petals, yellow to greenish yellow in color sometimes tipped with red, about 1 to 3.5 millimetres (0.039 to 0.138 in) long, and blooming in summer.

The first time that R. rosea is described was from Dioscorides in De Materia Medica”

Note of caution:

Adverse reactions:   Two subjects on 200 mg of R. rosea over a 4-week period each experienced a minor and serious headache,  one subject on placebo over a 2-day treatment period experienced a minor headache and another had insomnia. Another subject on placebo experienced hypersalivation . There appear to be few side effects associated with R. rosea supplementation; those identified are of a mild nature.  *see research link  PMC3541197/

Do not use in addition to normal anti-depressants or MAO inhibitors. It might cause interactions. *see research link 25413939

Having no addictive potential, Rhodiola rosea is a mild stimulant, so should be taken in the morning to avoid sleep problems. It may induce temporary vivid dreams and mild nausea. It also binds with the estrogen receptor, so women with a personal or family history of estrogen-sensitive breast cancer should exercise caution in using Rhodiola rosea  *see research link  PMC3660126/

Anti-inflammatory *see research link  PMC3652169/

Antioxidant  * see link 19705137

Stops nicotine withdrawal symptoms and prevents relapse (Excerpt from research:” Results show that both affective and somatic signs induced by nicotine withdrawal are abolished by administration of Rhodiola rosea L. extract.  “) *see research link 19939867 &  22921986  &  24264566

Anti- Cocaine craving properties.. (Excerpt from research:” The results obtained in this study demonstrate that RHO is capable of decreasing the rewarding effects of cocaine, since both acquisition and expression of a cocaine-induced CPP were impaired by RHO ( Rhodiola rosea L), though only with specific doses of this compound  “) *see research link PMC3794542/

Reduces morphine dependence (Excerpt from research:”  Results showed that Rhodiola rosea L. extract significantly reduced the expression of morphine tolerance   “) *see research link 20142299/

Improves endurance capacity and/or physical performance (Excerpt from research:” Three out of six parameters of endurance capacity (time to exhaustion, O2 uptake and CO2 output) significantly improved (p 

Reduces mental fatigue ( excerpt from research:”  Subjects were randomized into 2 groups to receive either 100 mg R. rosea once per day or identical placebo for 20 days. Significant improvements were observed in hand-eye coordination (p 

Improves overall mood , reduces anxiety & stress  (excerpt from research:” Relative to the controls, the experimental group demonstrated a significant reduction in self-reported, anxiety, stress, anger, confusion and depression at 14 days and a significant improvements in total mood “)  *see research link 26502953 , 18307390

Moderate anti-depressive action compared to normal anti-depressiva, but a lot less side effects (excerpt from research:”  present findings suggest that R. rosea may possess modest antidepressant effects in some patients with mild to moderate MDD  “major depressive disorder “.  “)  *see research link  PMC4385215/ ,     PMC4297663/  , /27013349 , 17990195

Anticancer against colon cancer, breast cancer &  some bladder cancer cell lines  (Excerpt from research:” The present study investigated the anticancer effects of salidroside on colon cancer cells, indicating a novel strategy for colon cancer treatment. In conclusion, salidroside can inhibit proliferation, arrest cell cycle, decrease the migration and invasion of the colon cancer SW1116 cells.     “)  *see research link  PMC4348934/, 25814002, PMC3144985/

Improves sensitive skin, topically applied  (excerpt from research:” Clinical effectiveness was measured by reduction of transepidermal water loss, positive perceptions of improvements in skin dryness and skin comfort sensation, and reduction of discomfort sensation after stinging test.  “)  *see research link  /18482014

Neuro-protective *see research link  PMC4117113/ , PMC3652169/

Cardio-protective (Except from research:” . Rhodiola rosea was found to prevent stress-induced cardiac damage. “) *see research link 7756969

Improves premature ejaculation in men  * see research link PMC5038509/

Anti-diabetes (Excerpt:” Rhodiola-water extract at 75 mg/kg significantly lowered the plasma glucose concentration “)   *see link PMC3897963/

Extends lifespan of  Drosophila fruitflies *see research link /PMC3660385/

Research on Rhodiola rosea:

http://www.webmd.com/vitamins-supplements/ingredientmono-883-rhodiola.aspx?activeingredientid=883

https://www.ncbi.nlm.nih.gov/pubmed/19939867

https://www.ncbi.nlm.nih.gov/pubmed/22921986

https://www.ncbi.nlm.nih.gov/pubmed/24264566

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794542/

https://www.ncbi.nlm.nih.gov/labs/articles/20142299/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541197/

https://www.ncbi.nlm.nih.gov/pubmed/26502953

https://www.ncbi.nlm.nih.gov/pubmed/23443221

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297663/

https://www.ncbi.nlm.nih.gov/pubmed/25413939

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385215/

https://www.ncbi.nlm.nih.gov/pubmed/27013349

http://accurateclinic.com/accurate-education-rhodiola-rosea/

https://www.ncbi.nlm.nih.gov/pubmed/17990195

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660126/

https://www.ncbi.nlm.nih.gov/pubmed/18307390

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391539/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117113/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652169/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313157/

https://www.ncbi.nlm.nih.gov/pubmed/7756969

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348934/

https://www.ncbi.nlm.nih.gov/pubmed/25814002

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144985/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038509/

https://www.ncbi.nlm.nih.gov/pubmed/19705137

https://www.ncbi.nlm.nih.gov/pubmed/18482014

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897963/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660385/

[nature420world]

Weed Related Questions Answered

Weed related questions-What’s up everyone, we are going to attempt to answer some of google top weed related questions. So grab your joints, spark up and enjoy.

Is smoking weed bad for your heart?

Are you about to get high but your wondering how does weed affect your heart rate? Then we got you covered. Have you ever gotten high and felt your heart starting to beat faster and faster? This is usually caused by marijuana itself, marijuana increases your heart rate by 20-50 beats per minute.

The reason for this spike in your heart rate is due to your body trying to compensate for the reduction in blood pressure caused by THC. Which could cause an abnormal heart rhythm, new research has found. Currently, there is not enough research to give a definitive answer to how does smoking weed affects your hearts.

Hopefully, once marijuana is declassified researchers and scientists will be able to fully study marijuana, concerning the human body.  

Source: NGUWeedShirts

How to lower heart rate when high on weed?

A few things you can do to help lower your heart rate when high

First, you should drink some water to make sure you’re not dehydrated

You could also try to eat something to help your body calm down

Taking a cold shower or running your hand under cold water will shock your body helping to bring down your heart rate.

You could try to do a few breathing exercises to help calm down your body

Meditating or doing yoga will also help to decrease your heart rate

Drinking milk will help to bring down your high and decrease your heart rate

Go outside and get some fresh air and take a walk.

Is smoking weed addictive?

Turns out a recent study on marijuana addiction shows that 30% of users may have some degree of marijuana use disorder. This study also showed that people who began using marijuana before age 18 could be 4-7 times more likely to develop a marijuana use disorder or addiction.

A marijuana use disorder is classified as a dependence that a person has for marijuana and their body’s reaction to stopping marijuana. This is represented through withdrawal symptoms when stopping use.

Such as irritability, mood swings, sleep difficulties, decreased appetite, restlessness & physical discomfort. These symptoms last on average a week or two, after quitting marijuana.

Marijuana dependence happens when your brain adapts to smoking large amounts of weed by reducing the production of and sensitivity to its endocannabinoid neurotransmitters.

In 2015 around 4.0 million Americans met the criteria to be diagnosed with a marijuana use disorder. Out of those 4.0 million Americans, 138,000 sought some form of treatment.  

For me, I think marijuana can be addictive for some people. There are a lot of marijuana users that have to or at least want to smoke weed every day. Then you got people who just smoke a few times a month.

I never really understood, how someone could just smoke like a few times a week. I think that these people have not developed a dependency or an addiction to weed. Making it easier for them to just casually smoke. I think there are a lot of contributing factors that help determine if a person will develop a weed dependency.

One factor could be your personality do you have an addictive personality? If so then you might be more likely to develop a dependency. Environmental factors also play a role. Are you in an environment where weed is always available? Then this might also cause you to consume more marijuana. Both factors can help to increase your overall consumption, which could lead to dependency.

If you’re afraid of becoming addicted to weed, moderation is the key. Take a break a few days a week. This will help to ensure that you won’t become addicted or dependent.

Source: Drug Abuse

Is smoking weed bad for cats?

Ever wonder how does marijuana smoke affects your cat. You might be thinking they eat catnip that’s almost the same thing. Turns out catnip does not work on all cats. Only a small percentage of cats who ingest catnip feel euphoric or high. Marijuana on the other hand can give your pets an intense high.

That could cause a variety of unwanted symptoms including extreme sleepiness, hypersalivation, dilated pupils, seizures, vomiting, low blood pressure, or even death. Your cat body is not equipped to handle large amounts of THC.  

You may be thinking but I have seen medical marijuana products for cats. This is true but usually, those products are low in THC & high in CBD. There is currently no study that shows the safest amounts of THC & CBD a cat can safely ingest. Pet owners usually have to go with a trial and error approach. A lot of cat owners have used CBD based product to help relieve their cats of joint pain and various illnesses.

If you feel as though your cat has ingested too much marijuana or smoke the safest thing to do is take them to the vet. Also, give them water to help push out the THC and to keep them hydrated.

On a side note, every animal is different, I am sure there are cat owners out there that probably blow smoke in their cat’s faces every day, without any lasting problems or issues. So just be safe…

Is smoking weed a felony?

Currently, marijuana is the most used illegal drug in the United States. Marijuana is currently decriminalized in numerous states across America but does that make weed legal? The answer is no even though some places have chosen to decriminalize marijuana, it’s still illegal across America on a federal level.

Federal law currently classifies marijuana as a Schedule 1 drug, first offenders can receive up to one year in jail and a minimum of $1000 fine. Your second marijuana arrest then becomes a felony. If you intended to sell it, then you’re looking at further actions as well being taken against you.

Some states across America have decided not to follow federal laws and just support state-enforced laws when it comes to marijuana.

Why does weed make you laugh?

Are you high and trying to figure out, why everything Is so funny. First of all, you probably have a good strain of weed, lol. So what’s the scientific reason why you laugh more while high? One reason is smoking weed gives you a detached perspective, which gives you the ability to see the world from an altered view.

This helps your brain to interpret your surrounding differently than you would normally. Marijuana also causes divergent thinking, this gives you the ability to make connections out of unrelated things and concepts. This happens in the right hemisphere of your brain. Where cognitive processes are interpreted like humor or sarcasm. An increase in blood flow to this part of the brain can cause everything to suddenly be funny or even improve creativity.

Another reason for laughing while high. Could also be the fact that Marijuana, naturally lifts your mood and perspective. Marijuana helps to release dopamine, which helps your body to feel good and relax making it easier to laugh.

Source: Pot Guide

Can smoking weed make you angry?

When you think of smoking weed, you might be thinking of someone happy or laughing. But what about the people who have negative experiences while smoking pot. Certain people’s bodies just don’t react well to marijuana. Marijuana is usually not the cause but a contributing factor. This could be caused by marijuana exasperating underline mental or emotional conditions. Which could make users irritated, stressed, or paranoid.

A study from the Alcohol and Drug Institute at Washington University shows a link between cannabis and aggressive behaviors in users during withdrawal periods.

Source: Lead Desk

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  Answering Weed Related Questions, Enter Now

Weed Related Questions Answered Weed related questions-What’s up everyone, we are going to attempt to answer some of google top weed related questions.

Answering Weed Related Questions, Enter Now Weed Related Questions Answered Weed related questions-What's up everyone, we are going to attempt to answer some of google top weed related questions.

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ORDER ALZHEIMERS AND PARKINSONS MEDICATIONS IN WORLDWIDE PHARMACIES

Alzheimers & Parkinsons is a category where you can find different medical agents against these two sicknesses and some conditions accompanied these ones. Alzheimer’s illness is an unrecoverable degenerative disease of the central nervous system characterized by gradual or progressive loss of mental capacities (memory, speech, logical thinking). The risk of this illness’s development heightens after the age of 65 years. It is one of the main reasons of feeble-mindedness beginning by aged patients. The specialists often tie together this sickness with destruction of nervous cells’ large quantity, some matters deficiency which are necessary for transfer of some nervous impulses, heredity (genetic predisposition), poisoning by toxic metals, heard trauma, brain’s tumour or hypothyroidism.

The last one’s treatment is a whole science and it is possible under the high-quality specialist’s participation only.

You have to know how to apply Alzheimers & Parkinsons pills and preparations

·         Nowadays there are different medical remedies which can support your health in tone under Alzheimer’s or Parkinson’s illnesses. You may apply these preparations under:

·         shaking palsy;

·         Parkinson’s disease;

·         symptomatic parkinsonism;

·         parkinsonian chorea;

·         secondary parkinsonism;

·         Alzheimer’s illness;

·         dementia of the Alzheimer’s type with light or moderate degree (including with accompanied insufficiency of cerebral blood circulation) and so on.

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Some of these drugs are also taken in quality of monotherapy in early stage of this sickness or in combination with levodopa’s medical agents. Some remedies are employed for diminishing of tremor, rigidity, hypokinesia, salivary discharge, dysphagy or muscles spasms under the Parkinson’s sickness. They are also very effective under the medical cure of several muscles spasms called by different narcotic drugs and other medical remedies (Thorazine, Prolixin, Trilafon and others). Some medicaments improve patients’ mood, normalize the facial expression and bring down the hypersalivation and face fattiness.

Parkinson’s sickness is a disease tied together with gradual death of motive nervous cells (neurons), produced the dopamine mediator. Due to this way it is broken the regulation and control of movements and muscular tonus that becomes apparent by typical tremor (tremble), general constraint and derangements of pose and motions.

 Before ordering and buying (Brand and Generic) each of Alzheimers & Parkinsons remedies online you get to read all side effects which can appear under the preparation’s applying in detailed instructions.

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