#esld

[phantomhealthcare]

World Hepatitis Day

Hepatitis affects millions, but it's preventable & treatable. On World Hepatitis Day, let’s raise awareness about getting tested and support those battling the virus. Together, we can eliminate hepatitis and ensure a healthier future for all!

[neck-thats-made-for-bruising]

Tragic: girl doesn't want to leave her bed to wash off her eyeliner but she has to

[gravehags]

https://www.instagram.com/reel/C5jam-ESlDE/?igsh=MzRlODBiNWFlZA==

I saw this and had to show you

Copia would absolutely have these and the rats would have free reign of the ministry

The ghouls don’t know what to make of

The siblings find it cute

-saturn

you’re the third person to share this with me and i love each and every one of you for it like copia’s rats just zooming up and down the corridors…i just know phantom goes full cat and starts chasing them on all fours

[asiya2000]

How Much Does Liver Transplant Costs in India?

The liver is our body's second-largest organ. It aids digestion by breaking down all of the nutrients in food and can withstand a lot of stress and abuse, but it can only go so far before getting into a stage of severe liver disease or cirrhosis. In recent times, the increase in demand for liver transplants has increased. If you are on this page, then you might be thinking of getting a liver transfer. Here we have discussed the procedure of getting a liver transfer along with liver transplant costs in India and many more.

What is a liver transplant?

A liver transplant is a procedure in which a diseased or unhealthy liver is replaced with one from a living or deceased donor. When a person has ESLD (End-Stage Liver Disease), a liver transplant is a last resort effort to save a dying patient's life. continue reading

[martinloren]

Exploring the Interplay Between Diseases and Liver Transplant

Understanding the Complexities and Implications

Liver transplant surgery is a life-saving procedure that offers hope to patients with end-stage liver disease and certain liver-related conditions. However, the decision to undergo a liver transplant is often influenced by the underlying disease or condition that necessitates the procedure. In this article, we delve into the intricate connection between diseases and liver transplants, exploring the complexities, implications, and considerations involved.

Liver Diseases Leading to Transplant: Liver transplant is commonly indicated for patients with end-stage liver disease (ESLD), a condition characterized by irreversible liver damage and loss of function. Chronic liver diseases such as cirrhosis, hepatitis B and C, alcoholic liver disease, non-alcoholic fatty liver disease (NAFLD), and autoimmune hepatitis are among the primary causes of ESLD. These diseases progress over time, leading to liver failure and ultimately necessitating a transplant to restore liver function and prolong survival.

Hepatobiliary Cancers: Hepatocellular carcinoma (HCC), the most common type of liver cancer, often develops in the setting of chronic liver disease or cirrhosis. In cases where the cancer is confined to the liver and has not spread beyond, liver transplant may be considered as a curative treatment option. However, stringent criteria and careful patient selection are essential to ensure favorable outcomes and prevent cancer recurrence post-transplant.

Metabolic Liver Diseases: Inherited metabolic disorders such as Wilson's disease, hemochromatosis, and alpha-1 antitrypsin deficiency can affect liver function and lead to progressive liver damage. For patients with severe and unmanageable symptoms, liver transplant may offer a chance for improved quality of life and long-term survival. However, the presence of underlying metabolic abnormalities may pose challenges during the transplant process and require specialized pre-transplant evaluation and management.

Acute Liver Failure: Acute liver failure (ALF) is a rare but life-threatening condition characterized by rapid onset of liver dysfunction and hepatic encephalopathy. Causes of ALF include viral hepatitis, drug-induced liver injury, autoimmune hepatitis, and acute fatty liver of pregnancy, among others. Liver transplant may be considered for select patients with ALF who fail to respond to medical therapy or develop complications such as hepatic coma. Timely referral and evaluation are crucial in optimizing outcomes for these patients.

Autoimmune Liver Diseases: Autoimmune liver diseases, including autoimmune hepatitis, primary biliary cholangitis (formerly known as primary biliary cirrhosis), and primary sclerosing cholangitis, are characterized by immune-mediated damage to the liver and biliary tract. While medical therapy is the mainstay of treatment for most patients, those with advanced disease and progressive liver failure may require liver transplant as a definitive treatment option. Careful management of post-transplant immunosuppression is essential to prevent disease recurrence and graft rejection.

Challenges and Considerations: Despite the potential benefits, liver transplant poses inherent challenges and considerations, particularly in the context of underlying diseases. Patient selection, pre-transplant evaluation, and post-transplant management require a multidisciplinary approach involving hepatologists, transplant surgeons, oncologists, and other specialists. Additionally, the shortage of donor organs, immunosuppression-related complications, and the risk of disease recurrence post-transplant are important factors to consider when weighing the risks and benefits of liver transplant in patients with underlying diseases.

The interplay between diseases and liver transplant is multifaceted and complex, with diverse implications for patient management and outcomes. While liver disease treatment in Bangalore, offers a lifeline to patients with end-stage liver disease, hepatobiliary cancers, metabolic disorders, acute liver failure, and autoimmune liver diseases, careful consideration of the underlying disease, patient characteristics, and transplant-related factors is essential in optimizing outcomes and ensuring long-term success. Through continued research, innovation, and collaboration, clinicians and researchers strive to advance our understanding of this intricate connection and improve the care and outcomes of patients undergoing liver transplant for various diseases.

Let’s know what are approaches taken to Liver transplant

Deceased Donor Liver Transplantation (DDLT) and Living Donor Liver Transplantation (LDLT) are two approaches to liver transplantation, each with its own distinct characteristics and considerations.

Donor Source:

Deceased Donor Liver Transplantation: Deceased Donor Liver Transplantation in Bangalore, the liver is procured from a deceased donor who has been declared brain-dead and has consented to organ donation either during their lifetime or by their family after death.

Living Donor Liver Transplantation: In Living Donor Liver Transplantation, the liver is donated by a living donor, typically a family member or close relative of the recipient. The donor undergoes a thorough evaluation process to assess their suitability for donation, including medical, psychological, and ethical considerations.

Timing of Transplantation:

Deceased Donor Liver Transplantation: The timing of Deceased Donor Liver Transplantation depends on the availability of deceased donor organs, which can vary depending on factors such as organ donation rates, waitlist prioritization, and organ allocation policies.

Living Donor Liver Transplantation: Living Donor Liver Transplantation offers the advantage of scheduling the transplant at a time that is convenient for both the recipient and the donor, minimizing the risk of disease progression and optimizing outcomes for both parties.

Graft Size and Compatibility:

Deceased Donor Liver Transplantation: The size and compatibility of the deceased donor liver may not always match the recipient's requirements, leading to potential mismatches in size or blood type. This can sometimes result in a longer wait time on the transplant waitlist or the need for additional surgical techniques to adapt the donor liver to the recipient's anatomy.

Living Donor Liver Transplantation: Living Donor Liver Transplantation allows for a more tailored approach to graft selection, as the donor liver can be selected based on size, blood type compatibility, and other factors specific to the recipient's needs. This often results in a better match and reduces the risk of graft rejection or complications post-transplant.

Waiting Time and Urgency:

Deceased Donor Liver Transplantation: Due to the limited availability of deceased donor organs, patients awaiting Deceased Donor Liver Transplantation may experience longer wait times on the transplant waitlist, particularly for those with less severe illness or lower priority status.

Living Donor Liver Transplantation: Living Donor Liver Transplantation offers the advantage of shorter waiting times, as the transplant can be scheduled based on the recipient's clinical status and urgency of need. This can be particularly beneficial for patients with rapidly progressive liver disease or acute liver failure who may not have the luxury of waiting for a deceased donor organ.

Risk to Donor:

Deceased Donor Liver Transplantation: There is no risk to the donor in Deceased Donor Liver Transplantation, as the liver is procured from a deceased donor who has already passed away.

Living Donor Liver Transplantation: Living Donor Liver Transplantation carries inherent risks to the living donor, including potential complications related to the surgical procedure, anesthesia, and recovery process. However, advances in surgical techniques and donor selection criteria have significantly reduced the risk of complications for living donors in recent years.

while both Deceased Donor Liver Transplantation and Living Donor Liver Transplantation in Bangalore,  offer life-saving options for patients with end-stage liver disease, each approach has its own unique characteristics, considerations, and advantages. The choice between Deceased Donor Liver Transplantation and Living Donor Liver Transplantation depends on various factors, including the recipient's clinical status, urgency of need, compatibility, and availability of suitable donor organs. Ultimately, the goal of liver transplantation is to provide the best possible outcome for the recipient while ensuring the safety and well-being of the donor.

For details get the specialists for the Best Liver Transplant Center in Bangalore

[bhumika-24]

Liver Transplantation- Reviving Hope

Liver transplantation is a surgical procedure that involves replacing a diseased or damaged liver with a healthy liver from a deceased or living donor. It is considered the most effective treatment for end-stage liver disease and certain liver conditions, offering a chance for survival and improved quality of life. This comprehensive article provides an overview of liver transplantation, including the procedure, common causes necessitating a transplant, treatment options, and symptoms associated with liver disease.

Causes Necessitating a Liver Transplant

Several conditions may require a liver transplant:

1. End-Stage Liver Disease (ESLD): ESLD refers to the final stage of liver disease, where the liver's function is severely compromised. Common causes include chronic hepatitis B or C, alcoholic liver disease, non-alcoholic fatty liver disease (NAFLD), cirrhosis, primary biliary cholangitis (PBC), primary sclerosing cholangitis (PSC), and genetic disorders such as hemochromatosis and Wilson disease.

 2. Acute Liver Failure (ALF): ALF is a sudden and severe deterioration of liver function. Causes of ALF can include viral hepatitis, drug-induced liver injury, autoimmune hepatitis, Wilson disease, and acetaminophen overdose.

 3. Liver Cancer: Liver transplantation may be considered for patients with hepatocellular carcinoma (HCC) within specific criteria, as the transplant provides an opportunity for tumor removal and improved long-term survival.

Symptoms of Liver Disease

Liver disease can present a variety of symptoms, which may include:

1. Jaundice: Yellowing of the skin and eyes due to the accumulation of bilirubin, a yellow pigment produced by the liver.

 2. Fatigue and Weakness: Persistent tiredness, weakness, and reduced energy levels.

 3. Ascites: Accumulation of fluid in the abdomen, causing abdominal swelling and discomfort.

 4. Weight Loss: Unintentional weight loss, often accompanied by a loss of appetite and malnutrition.

 5. Itching: Intense itching of the skin, resulting from the buildup of bile acids.

 6. Nausea and Vomiting: Persistent nausea, occasional vomiting, and loss of appetite.

 7. Changes in Stool and Urine: Pale, bloody, or tar-colored stool, and dark-colored urine.

 8. Abdominal Pain: Pain or discomfort in the upper right abdomen, often accompanied by swelling or tenderness.

Liver Transplant Procedure

1. Pre-Transplant Evaluation:

  Patients undergo a comprehensive evaluation to determine their eligibility for a liver transplant. This includes medical history review, physical examination, blood tests, imaging studies, and various assessments to evaluate overall health and the severity of liver disease. Psychological and social evaluations are also conducted.

 2. Donor Selection:

  Donor selection is a critical step in liver transplantation. Donors can be deceased or living (usually a family member or close friend). Compatibility is determined based on blood type, size compatibility, and overall health of the donor. Cadaveric liver transplantation relies on organ donation from deceased individuals.

 3. Surgical Procedure:

  The liver transplantation surgery typically takes several hours and is performed under general anesthesia. The diseased liver is removed, and the healthy donor liver is implanted. The blood vessels of the new liver are connected to the recipient's blood vessels, and the bile ducts are attached to ensure proper bile flow. Surgical techniques may vary, including whole liver transplantation or living-donor liver transplantation (LDLT), which involves using a portion of a healthy liver from a living donor.

 4. Post-Operative Care:

  Post-transplant care is crucial for successful recovery. Close monitoring is performed to ensure proper graft function, early detection of complications, and management of immunosuppression medications to prevent organ rejection. Regular follow-up visits, laboratory tests, and imaging studies are conducted to monitor liver function and overall health.

Treatment of Liver Disease

1. Medications:

  Medications play a crucial role in managing liver disease and post-transplant care. They may include antiviral medications for viral hepatitis, immunosuppressants to prevent organ rejection, diuretics to manage fluid retention, and medications to control symptoms and complications such as jaundice, itching, and portal hypertension.

 2. Lifestyle Changes:

  Lifestyle modifications can significantly impact liver health. These may include abstaining from alcohol consumption, maintaining a healthy weight, adopting a balanced diet, exercising regularly, and avoiding exposure to hepatotoxic substances.

 3. Hepatitis Treatment:

  Specific antiviral medications are used to manage hepatitis B and C infections, aiming to suppress viral replication and prevent further liver damage. In some cases,successful treatment of hepatitis may eliminate the need for a liver transplant.

 4. Palliative Care:

  In cases where a liver transplant is not feasible or when the disease is advanced, palliative care focuses on providing relief from symptoms, improving quality of life, and addressing the patient's physical, emotional, and psychological needs.

Liver Transplant Cost in India

The cost of a liver transplant in India is significantly lower compared to many other countries, making it an appealing choice for patients seeking cost-effective treatment options. The average cost of a liver transplant in India is around USD 12000–25000 which includes the surgery, hospital stay, medications, and follow-up care.

 Liver transplantation is a life-saving procedure for individuals with end-stage liver disease or other liver conditions. The procedure, combined with appropriate medical management, offers a chance for improved quality of life and long-term survival. Early diagnosis, prompt treatment, and close monitoring of liver disease symptoms are essential for timely intervention and consideration of a liver transplant when necessary. Ongoing research and advancements in transplantation techniques continue to improve outcomes and provide hope for patients with liver disease.

[drforambhuta]

Liver failure is a condition in which liver damage occurs to such an extent that the liver fails to work well. The various stages that cause liver failure include:

Inflammation: This is the early stage of liver inflammation or enlargement. If the liver inflammation continues, it may cause permanent liver damage.

Fibrosis: This condition develops when an inflamed liver begins scarring. The scar tissue formed at this stage takes the place of the healthy liver tissue and begins to affect the ability of the liver to function properly.

Cirrhosis: This stage involves severe scarring in the liver. More and more healthy liver tissue gets replaced by scars, which makes it difficult for the liver to function properly.

End-stage liver disease (ESLD): This stage involves liver cirrhosis in which the function of the liver dramatically reduces.

Liver cancer: The development and multiplication of unhealthy cells in the liver cause primary liver cancer.

There are many hospitals in Bangalore where liver transplant is done with great success.

[drpriya]

Liver failure is a condition in which liver damage occurs to such an extent that the liver fails to work well. The various stages that lead to liver failure include:

Inflammation: This is the early stage of liver inflammation or enlargement. If the liver inflammation continues, it may lead to permanent liver damage.

Fibrosis: This condition develops when an inflamed liver begins scarring. The scar tissue that is formed at this stage takes the place of the healthy liver tissue and begins to affect the ability of the liver to function properly.

Cirrhosis: This stage involves severe scarring in the liver. More and more healthy liver tissue is replaced by scars, which makes it difficult for the liver to function properly.

End-stage liver disease (ESLD): This stage involves liver cirrhosis in which the function of the liver has dramatically reduced.

Liver cancer: The development and multiplication of unhealthy cells in the liver lead to primary liver cancer.

In cases of liver failure, liver transplant is done.

There are many hospitals in Chennai where liver transplant is done with great success.

[thegraymethod]

When the doc's progress note says "continue Q2h lactulose overnight"

[weirdgurlvermil]

So over this crap. #insomnia #esld #sleep #painsomnia #melatonin #circadianrhythm #sickofthis (at Doncaster)

[www99909]

Natural language processing helps evaluate electronic messages from ESLD patients

http://news.healthtipsblog.net/2019/11/natural-language-processing-helps.html

[doctorfoxtor]

Me brain no work

100 days of productivity

Day 2

RS/CVS:

Flecainide is highly arrhythmogenic in structural/ischaemic heart disease. Also like verapakill it's a strong negative inotrope and hence should not be used in HFrEF

Non-provoked DVT-PTE: 6 months of anticoagulation. Provoked, temporary cause of DVT-PTE (recent surgery, immobility, etc): 3 months anticoagulation. Provoked, sustained cause of DVT-PTE: depends on the cause but usu. lifelong.

Dipyridamole can be given lifelong in those who can't tolerate P2Y12 inhibitors

Endocrine/Repro:

Incretinoids (GLP-1as/DPP-4is) can trigger severe pancreatitis and also have to be renally dosed

Riedel thyroidits assoc. with retroperitoneal fibrosis. Also it mimics cancer (hard fixed lump in neck)

MODY: HNF-1a mutation

Renal/Biochem:

Thiazides induce the most pronounced hyponatraemia of most medications, and on top of that they can also cause SIADH

Gastro:

Urea breath test is the investigation of choice to confirm H pylori eradication after therapy

Liver detoxification: phase 1/redox reactions are impaired in early liver disease, but phase 2/conjugation reactions are only impaired in ESLD

Haem/Onc:

Anaemia with disproportionately low MCV for Hb: think spherocytosis and thalassaemia! Can differentiate with MCHC (high in sphero, normal/low in thal) or peripheral smear.

Macrocytic anaemia + normal haematinic parameters = myelodysplastic syndrome

Philadelphia chromosome is a poor prognostic marker in acute leukaemias

Methotrexate's anticancer activity is through inhibition of pyrimidine synthesis (specifically thymidylate: dUMP → dTMP) whereas its DMARD activity is through inhibition of purine synthesis

Alkylating agents are the only chemotherapeutics that can target cells in the G0 phase

When switching oral morphine to subcutaneous morphine, use 1/2 the total daily oral dose; when switching oral morphine to subcutaneous diamorphine, use 1/3rd the total daily oral dose (eg, 60 mg q12h oral MSO4 = 60 mg qDay subQ MSO4 = 40 mg qDay subQ diamorphine)

[thesoftwarereview]

Life After Sms Logger Android Free

The Basic Facts of Sms Logger Android Free

The repair center needs to have the capacity to seek out any keylogger on your PC. You may naturally check above their multimedia directory. You are likely to get a whole package of free cell phone traveler system! Without stealth mode, that might never be generally known as a traveler. In regards to picking the ideal Android Keylogger there are many characteristics that ought to be considered.

Ok, I Think I Understand Sms Logger, Now Tell Me About Sms Logger Android Free !

The dimension also differs with respect to the capacity combined with the support offered the unique sort of PBX used. This logger records at multiple bitrates, does not have any storage restrictions, and is not hard to utilize. For benefit of different unit known as a GPS data logger, then you have to upload its coordinates onto your computer later.

It will do the job even though you get the voice mail. Consequently, if you should be considering an exas telephone log without their agreement, it is illegal. It looks to copy not merely your SMS messages, and also your MMS people, and also the phone record.

The mobile phone tracker is. Cell phone tracking application can help in locating a loved one with the use of the GPS on the cellular phone. Send an SMS to the telephone and it’ll call you back.

Top Choices of Sms Logger Android Free

Like how it’s real time on each of the issues this app gives! To stop this chaos, the software lets you avoid these uncomfortable cases till they cause actual difficulty. Beware, the way you use these programs.

The pieces of these things will also be available on the market. This also aids the little business properties in archiving their business stereo stations. Should you not should make cost reports but must locate a handle on cutting back on private charges, Dollarbird is for you.

The Hidden Treasure of Sms Logger Android Free

At this time, you never must be concerned about missing anything as PhoneSheriff is there to search for all of your spying requirements. It is possible to almost certainly think of more ways too. You can’t record the real calls but I am aware they’re trying to do that.

These sorts of applications contain a number of the most recent and most dubious varieties of Android spy programs. You’re ready to test the totally free presentations easily obtainable on Copy9 website. Reducing it nor produce you shake!

The Debate Over Sms Logger Android Free

This is planning to be the most effective instrument you have whenever you want employed to learn the hidden truth. In truth which you do not wish to do anything, merely utilize completely free desktop plan on the internet to turn your computer data logger is coordinates right into a post to the map. If you have started the monitoring it’ll continue being productive from that moment.

It also provides zero cost customer care in case you want it. The App permits you to begin looking for contact registry along side everything plus you could also change look-up the contacts to learn more. When you address the product, you’ve the chance to create an account where it is possible to join safely to gain access to bill - related facts.

What the In-Crowd Won’t Tell You About Sms Logger Android Free

Cybercriminals might also get to. Well, UIAutomation enables you to bargain with that. And this is fairly difficult to say. It is fully hidden rather than shown whatsoever.

Eat with cellular great teenagers couldn’t mean. Alternatively it targets assisting you to find out where your hard-earned cash is certainly going so that you can quickly scale back on expenditures. Nobody will quickly realize that, so people have the ability to obtain the many real side of kids, partner and employees.

You can commonly prevent the programs that are not age appropriate. Male is esld you’re planning to have represented. The Toddler Tag Child Locator is a system that’ll let you truly discover your son or daughter in virtually any crowded area or in just a large open site.

No complicated tracking application is important. It also contains a data system, and is both self- closed and self- operated. It offers ways to build the CDR data.

[pusware]

Autumn

Summertime is hiking and golf season in the Great Pacific Northwest, so much of last week was spent in those activities at the Oregon Coast. I am fortunate that two of my favorite pastimes are safe in the time of COVID 45. I disconnect from the world when I am not working, and I am always amazed at the US approach to COVID when I return to life.

We are so doomed.

But this blog could be considered the ID equivalent of the band on the Titanic, playing while the ship went under. And a one and a two.

The patient has ESLD and is admitted with abdominal pain, fevers, and rigors.

The exam has ascites, rebound and guarding, and parameters from a paracentesis are consistent with SBP.

The ascites cultures are negative, but the blood grows a small gram-negative rod:

Continue reading at http://boards.medscape.com/forums/?128@@.2a8460a6!comment=1

[iamtheamster-blog]

5

That’s all, just 5.