#crisis prepping

[shadesofdigital]

🌍 The World is Changing: Are You Ready? 🌍

Right now, we are living in unprecedented times. Political tensions are rising, racial divisions are deepening, the migrant crisis is overwhelming our cities, and violence seems to be at every corner. Inflation is making it harder to get by, the Israel/Palestine conflict continues to escalate, and homelessness is becoming a growing crisis. As Black people, we have always been resilient, but now is the time to prepare and protect what matters most—our families.

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[reasonsforhope]

"A large clinical trial in South Africa and Uganda has shown that a twice-yearly injection of a new pre-exposure prophylaxis drug gives young women total protection from HIV infection.

The trial tested whether the six-month injection of lenacapavir would provide better protection against HIV infection than two other drugs, both daily pills. All three medications are pre-exposure prophylaxis (or PrEP) drugs.

Physician-scientist Linda-Gail Bekker, principal investigator for the South African part of the study, tells Nadine Dreyer what makes this breakthough so significant and what to expect next.

Tell us about the trial and what it set out to achieve

The Purpose 1 trial with 5,000 participants took place at three sites in Uganda and 25 sites in South Africa to test the efficacy of lenacapavir and two other drugs.

Lenacapavir (Len LA) is a fusion capside inhibitor. It interferes with the HIV capsid, a protein shell that protects HIV’s genetic material and enzymes needed for replication. It is administered just under the skin, once every six months.

The randomised controlled trial, sponsored by the drug developers Gilead Sciences, tested several things.

The first was whether a six-monthly injection of lenacapavir was safe and would provide better protection against HIV infection as PrEP for women between the ages of 16 and 25 years than Truvada F/TDF, a daily PrEP pill in wide use that has been available for more than a decade.

Secondly, the trial also tested whether Descovy F/TAF, a newer daily pill, was as effective as F/TDF...

The trial had three arms. Young women were randomly assigned to one of the arms in a 2:2:1 ratio (Len LA: F/TAF oral: F/TDF oral) in a double blinded fashion. This means neither the participants nor the researchers knew which treatment participants were receiving until the clinical trial was over.

In eastern and southern Africa, young women are the population who bear the brunt of new HIV infections. They also find a daily PrEP regimen challenging to maintain, for a number of social and structural reasons.

During the randomised phase of the trial none of the 2,134 women who received lenacapavir contracted HIV. There was 100 percent efficiency.

By comparison, 16 of the 1,068 women (or 1.5%) who took Truvada (F/TDF) and 39 of 2,136 (1.8%) who received Descovy (F/TAF) contracted the HIV virus...

What is the significance of these trials?

This breakthrough gives great hope that we have a proven, highly effective prevention tool to protect people from HIV.

There were 1.3 million new HIV infections globally in the past year. Although that’s fewer than the 2 million infections seen in 2010, it is clear that at this rate we are not going to meet the HIV new infection target that UNAIDS set for 2025 (fewer than 500,000 globally) or potentially even the goal to end Aids by 2030...

For young people, the daily decision to take a pill or use a condom or take a pill at the time of sexual intercourse can be very challenging.

HIV scientists and activists hope that young people may find that having to make this “prevention decision” only twice a year may reduce unpredictability and barriers.

For a young woman who struggles to get to an appointment at a clinic in a town or who can’t keep pills without facing stigma or violence, an injection just twice a year is the option that could keep her free of HIV.

What happens now?

The plan is that the Purpose 1 trial will go on but now in an “open label” phase. This means that study participants will be “unblinded”: they will be told whether they have been in the “injectable” or oral TDF or oral TAF groups.

They will be offered the choice of PrEP they would prefer as the trial continues.

A sister trial is also under way: Purpose 2 is being conducted in a number of regions including some sites in Africa among cisgender men, and transgender and nonbinary people who have sex with men.

It’s important to conduct trials among different groups because we have seen differences in effectiveness. Whether the sex is anal or vaginal is important and may have an impact on effectiveness.

How long until the drug is rolled out?

We have read in a Gilead Sciences press statement that within the next couple of months [from July 2024] the company will submit the dossier with all the results to a number of country regulators, particularly the Ugandan and South African regulators.

The World Health Organization will also review the data and may issue recommendations.

We hope then that this new drug will be adopted into WHO and country guidelines.

We also hope we may begin to see the drug being tested in more studies to understand better how to incorporate it into real world settings.

Price is a critical factor to ensure access and distribution in the public sector where it is badly needed.

Gilead Sciences has said it will offer licences to companies that make generic drugs, which is another critical way to get prices down.

In an ideal world, governments will be able to purchase this affordably and it will be offered to all who want it and need protection against HIV."

-via The Conversation, July 3, 2024

[uncanny-tranny]

I won't rest until we start dispensing PrEP in every vending machine and people all over regardless of if they're in a straight relationship or a normal one or are single or whatever else are taking it. It shouldn't be seen as "the drug the queers take" because (spoilers!) Everyone Can Get HIV and It Does Not Discriminate.

[allwitnobrevity]

Just a little comic I drew while I was stuck inside with approximately the 907th severe weather alert of the year

[prep4tomoro]

Survival Clothing What to Wear:

It would be great to know where we will be and what the temperature will be like when the SHTF. But that ain't a gonna happen and you can't carry everything for every little situation. Here are some things to consider as a general rule for the unexpected and the planned outing:

Wool vs Cotton: Wool is best for cold weather while cotton is best for warmer weather. Wool is a powerful insulator. In fact, it's the second-best natural insulator next to goose down. It also repels water and wicks moisture. The lanolin, with its antibacterial, antimicrobial and water repellant properties, can irritate skin and can't be removed simply through washing. It's more durable and more wrinkle-resistant than cotton and it hardly retains odors and stains. Cotton, on the other hand, is a warm-weather fabric. Like wool, cotton has moisture-wicking properties. But the difference between wool vs. cotton is that cotton is a light, breathable fabric that helps you stay cool in the summer. It also provides excellent protection against the ultraviolet rays of the sun. It's hypoallergenic, easy to care for, and affordable.

Survival Clothing Principles:

Your body helps regulate body temperature. Clothing should work WITH your body. Exercise can help keep you warm in the winter and hydration (water intake) will help keep you cool in the summer.

Bulky or tight clothing is bad for survival. Synthetic [lighter/thinner] "fabrics" may be better options.

What you have with you when SHTF will be your survival clothes. Keep your "survival" clothing near you at all times (in a bug-out bag that is WITH YOU).

Dress for the function, not the fashion/form; the proper clothing for the situation.

Dress to blend in with the environment (gray man).

Related Resources: Choosing the Correct BugOut Clothes Clothing for Survival and BugOut Situations The Survival Clothing - Must-Haves for Any Situation Stretch Shoes/Boots With Ice Know How to Make Primitive Footwear Making Wilderness/Survival Snowshoes Winterizing Toes and Fingers Primitive Needle and Thread Clothes When You Are Living Off Grid Clothing to Protect from Sun and Insects Insect Protection:    [Link 1]    [Link 2] Clothing Repair Kit (and What to Do if You Don't Sew) Learn to Make Your Own Clothes From Scratch How to Dry Wet Clothes in the Wilderness Emergency Insulation Materials to Stay Warm or Cool

[11-Cs Basic Emergency Kit] [14-Point Emergency Preps Checklist] [Immediate Steps to Take When Disaster Strikes] [Learn to be More Self-Sufficient] [The Ultimate Preparation] [P4T Main Menu]

This blog is partially funded by Affiliate Program Links and Private Donations. Thank you for your support.

[flythesail]

Every time Osha meets with Darth Plagueis it's like how badly can I twist her perspective and everything she believes so she doubts everything and especially herself again

[pocketramblr]

... hey guys does infinite crisis uh. start on father's day

[tifa-simp]

The real tragedy of Rebirth is what keeps happening to Tifa and her scalp actually.

[siphisket]

It’s been a little while since I’ve posted about Banesbrook, so I wanna provide a brief update for the lovely folks who have shown interest in our little game.

First of all, Banesbrook is still happening! Since it’s an un-funded hobby project, timelines are a bit tricky to nail down, but all of the art, music, dialogue, and everything are prepped and ready for the Level 1 Demo, and even quite a bit beyond that!

The only thing that’s kept us from publishing the demo for nearly a year now is coding. We’ve hit a ton of road bumps along the way, ranging from irl scheduling conflicts to full-scale data loss, and even a legal scare when a former team member's age came to light. That last obstacle is the latest, and unfortunately, it means that for the second time, we’ll to have to start over the coding from scratch. While this will put us significantly behind schedule, it's important to us that we do not violate child labor law (especially while working on a game containing themes of childhood mistreatment).

Due to irl complications from before this issue came to light, I’ve had to indefinitely step away from the administrative duties involved in running a dev team, but despite everything, our coders have remained dedicated to rebuilding the demo so it doesn’t get fully shelved. It will be very slow going, but it’s going!

And some other good news! Since before we started working together, one of our coders has been working on his own game called Roswell’s Journey, and while I’ve wanted to keep Banesbrook in hobby territory, he went and started his own indie game studio called BitRate Games! Roswell’s Journey is currently in pre-alpha, and folks, this game looks so cool, I seriously can’t wait!

If you’re looking for an upcoming indie game to sink your teeth into, check it out here! (Or wishlist it on Steam!)

TL;DR — Banesbrook will be on the back burner for a while, but one of our amazing coders has an upcoming indie game coming soon, so keep an eye out for Roswell’s Journey!

[shadesofdigital]

Are you ready for the unexpected?

Life throws curveballs. Natural disasters, power outages, and unforeseen emergencies can disrupt our lives at any moment.

Are you prepared to face the unknown?

The Urban Survival Playbook will equip you with the knowledge and skills to navigate through challenging situations with confidence.

Learn how to:

Build a robust emergency kit

Develop a family emergency plan

Acquire essential survival skills

Enhance your self-reliance

Find peace of mind knowing you're prepared

Download your Urban Survival Playbook today and take the first step towards a more secure future.

[mens-reas]

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[natinalpartisan]

Choosing the Right Survival Prepping Option: A Guide to Find Your Best Fit

In uncertain times, being prepared for emergencies is crucial. But with numerous survival prepping options available, finding the right one for you can be overwhelming. Fear not, as this comprehensive guide is here to help. Whether you're a city dweller or a wilderness enthusiast, this resource will navigate you through various prepping options, from bug-out bags to homesteading, self-sufficiency to tactical prepping. Discover the essentials of food storage, water purification, emergency shelter, and first aid. Uncover the secrets of outdoor survival and wilderness skills. Explore the realms of self-defense, alternative energy, and crisis management. Equip yourself with the knowledge to make informed decisions and ensure your readiness for any situation.

[prep4tomoro]

Learn how to Use Manual and Electric/Battery Hand Tools:

Learn how to use manual and electric/battery hand tools for all sorts of repair jobs, DIY projects, and general upkeep. Half the fun of embarking on a DIY project or maintaining your home is choosing the best tools for the job. As the years go by and your projects get more ambitious, you'll likely accumulate hundreds of tools. But these are the essential tools you can't live without, and will turn to them time and again for general upkeep and specialized jobs like a saw, jig saw, drill, wrench, pliers, needle-nose pliers, socket wrench, allen wrench, different types of screwdrivers, claw hammer, chainsaw, clamps, vise, tire guage, wire cutters, tin snips, pocket knife or multi-tool, ladder, soldering iron, sander, and others.

Related Resources: 10 Tools Everyone Should Learn to Use 50 Tools Everyone Should Own Videos Benefits of Non-Power Hand Tools Survival Tools Crafted from Ordinary Items DIY Woodworking [Viking] Clamps and Vise Learn to Properly Use Log-Cutting Tools [Author's Reference Link]

[11-Cs Basic Emergency Kit] [14-Point Emergency Preps Checklist] [Immediate Steps to Take When Disaster Strikes] [Learn to be More Self-Sufficient] [The Ultimate Preparation] [P4T Main Menu]

This blog is partially funded by Affiliate Program Links and Private Donations. Thank you for your support.

[theskydoesgreatthingsnow]

‼️ATTENTION Faggots! Sex Workers! People With Bodies‼️

Your rights to PrEP, Cancer Screenings, and other preventive care are at risk!

A Texas Judge (who previously failed to overturn ACA) invalidated the preventative care statute, which required insurance to fully cover vital preventative certain cancer screenings and PrEP. Your right to life saving HIV protection is at risk!

This is super fucking important for our community. It is also a directly motivated, violent homophobic attack. Not in a internet “homophobic in effect ergo one could say” way—

‼️The stated motivation of the man who brought the suit is to use AIDS to punish homosexuality and sex work. ‼️

Conservative mega donor Dr Steven Hotze, a anti gay hate group founder, election denier, Covid conspiracy theorist, and person who filled the suit that led to this decision has stated that HIV Pre exposure drugs “facilitate behaviors such as homosexual sodomy, prostitution, and intravenous drug use” which conflicts with his religious beliefs. I repeat THE POINT IS FOR AIDS TO PUNISH HOMOSEXUALITY.

(The Hotze is now charged in connection with an agrivated assault of a repairman by a PI hired by the mega-donor to “confirm” election fraud. We might live in hell.)

This may come down to a legal fight, this may be out of the hands of protesters. BUT WATCH THIS DEVELOPMENT AND PREPARE FOR COMMUNITY ACTION.

It is possible that you are not at immediate risk. Most employers and insurers will keep these kinds of care fully covered for the same reason it was mandated: it is the ethical choice, and it saves them way more than it costs. But roughly one in five may try to save money by asking at risk groups to pay out of pocket.

And the problem will only grow more acute and widespread. Things like anxiety screenings, contraception, and many interventions for the chronically ill are also at risk of returning to pre ACA levels of financially burden, at the whims of corporate interests.

[mellow-killjoy]

I think making out to 'Violence' and 'Fever Dream' by Frank iero and the future violents would solve like 90% of my problems

The other 10% by fucking to pencey prep

It's better then therapy